[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr2:231,628,878-234,434,621

Best TWAS P=2.81e-15 · Best GWAS P=4.29e-13 conditioned to 0.1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	EIF4E2	0.09	0.06	lasso	1	0.05	1.7e-04	5.6	-5.5	2.8e-08	0.02	0.78	0.02	FALSE
2	GTEx	Brain Cerebellar Hemisphere	PTMA	0.28	0.12	enet	19	0.06	1.5e-02	-5.7	5.5	3.9e-08	-0.52	0.05	0.53	FALSE
3	GTEx	Brain Frontal Cortex BA9	C2orf82	0.24	0.16	lasso	10	0.12	3.9e-04	-4.4	5.1	2.9e-07	0.01	0.04	0.93	FALSE
4	GTEx	Brain Putamen basal ganglia	C2orf82	0.28	0.22	lasso	3	0.18	5.3e-05	-4.5	5.3	1.4e-07	0.00	0.04	0.77	FALSE
5	GTEx	Heart Atrial Appendage	COPS7B	0.22	0.01	lasso	6	0.01	1.3e-01	-5.7	-6.4	1.3e-10	0.76	0.05	0.24	FALSE
6	GTEx	Liver	PDE6D	0.21	0.10	lasso	4	0.09	1.8e-03	-7.0	-7.5	6.4e-14	0.81	0.01	0.90	TRUE
7	GTEx	Thyroid	GIGYF2	0.08	0.02	lasso	3	0.01	6.7e-02	-5.7	-5.4	8.2e-08	-0.01	0.10	0.16	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	NCL	0.16	0.05	lasso	6	0.08	6.1e-10	4.3	6.1	8.5e-10	0.06	0.07	0.93	TRUE
9	YFS	Blood	EIF4E2	0.06	0.04	enet	27	0.04	2.8e-13	5.6	6.0	2.2e-09	-0.02	0.99	0.01	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C2orf52	0.15	0.14	enet	8	0.13	3.7e-11	-5.4	5.4	6.8e-08	0.00	0.18	0.82	FALSE
11	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C2orf52	0.28	0.12	lasso	6	0.12	2.0e-06	-5.8	6.0	1.7e-09	-0.01	0.03	0.97	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	C2orf52	0.21	0.16	blup	42	0.24	7.1e-14	-5.2	5.4	5.8e-08	0.02	0.08	0.92	FALSE
13	The Cancer Genome Atlas	Glioblastoma Multiforme	C2orf52	0.28	0.12	enet	12	0.18	5.0e-06	-5.2	5.7	1.5e-08	0.00	0.03	0.86	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C2orf52	0.23	0.25	enet	12	0.28	2.9e-32	-5.5	5.2	1.5e-07	0.00	0.12	0.88	FALSE
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C2orf52	0.18	0.20	lasso	3	0.19	3.4e-11	-5.2	5.2	1.6e-07	0.01	0.12	0.88	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EFHD1	0.11	0.01	blup	70	0.03	1.0e-02	5.3	7.9	2.8e-15	-0.01	0.02	0.70	TRUE
17	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	KCNJ13	0.07	0.06	enet	13	0.05	4.7e-04	-6.2	5.4	6.7e-08	-0.01	0.02	0.91	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	GIGYF2	0.02	0.01	lasso	3	0.01	5.3e-02	-6.2	-6.3	2.8e-10	0.00	0.03	0.87	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	NGEF	0.03	0.01	blup	130	0.01	2.0e-02	-6.2	5.2	2.1e-07	0.00	0.02	0.90	FALSE
20	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C2orf52	0.13	0.06	lasso	4	0.05	2.1e-03	-5.4	5.3	1.1e-07	0.00	0.04	0.45	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	CHRNG	0.04	0.00	blup	58	0.00	1.3e-01	3.4	-6.3	2.4e-10	0.12	0.01	0.33	TRUE
22	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C2orf52	0.28	0.18	lasso	4	0.20	3.7e-22	-5.8	5.6	2.2e-08	0.00	0.03	0.97	FALSE
23	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C2orf52	0.24	0.20	lasso	3	0.20	1.4e-13	-5.2	5.2	1.9e-07	0.00	0.16	0.84	FALSE
24	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C2orf52	0.32	0.21	lasso	7	0.21	3.6e-09	-5.2	5.3	1.4e-07	-0.03	0.08	0.92	FALSE
25	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	KCNJ13	0.07	0.07	blup	36	0.06	2.4e-03	-6.2	5.9	3.0e-09	0.00	0.01	0.88	FALSE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C2orf52	0.27	0.27	lasso	5	0.28	1.7e-11	-5.4	5.4	5.3e-08	0.00	0.12	0.88	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	GIGYF2	0.04	0.00	blup	103	0.02	2.1e-03	-4.5	-5.8	7.4e-09	0.02	0.04	0.80	FALSE
28	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C2orf52	0.21	0.20	lasso	1	0.18	1.4e-05	-5.8	5.8	7.0e-09	0.02	0.02	0.75	FALSE
29	The Cancer Genome Atlas	Stomach Adenocarcinoma	C2orf52	0.12	0.10	enet	11	0.12	5.6e-09	-5.2	5.1	3.0e-07	0.03	0.07	0.93	FALSE
30	The Cancer Genome Atlas	Stomach Adenocarcinoma	KCNJ13	0.09	0.06	blup	36	0.08	3.8e-06	-6.2	5.2	2.3e-07	0.00	0.01	0.98	FALSE
31	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C2orf52	0.29	0.17	enet	10	0.19	3.2e-07	-5.4	5.6	2.2e-08	-0.02	0.07	0.89	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	EIF4E2	0.03	0.01	blup	63	0.02	4.7e-03	5.6	-5.2	2.1e-07	0.08	0.01	0.84	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	KCNJ13	0.03	0.00	blup	35	0.01	4.3e-02	5.2	-6.9	6.9e-12	0.00	0.01	0.56	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	NGEF	0.04	0.03	enet	7	0.03	5.6e-04	5.3	-6.4	1.6e-10	0.01	0.04	0.93	FALSE