TWAS hub - RNPS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1080	0.0340	1.3e-04	0.053	0.038	0.052	0.048	0.051	4.5e-07	1.8e-05	5.3e-07	1.7e-06	6.6e-07
2	GTEx	Adipose Subcutaneous	0.1060	0.0420	3.6e-03	0.079	NA	0.065	NA	0.073	5.4e-07	NA	5.1e-06	NA	1.5e-06
3	GTEx	Brain Cerebellar Hemisphere	0.4640	0.0920	4.4e-05	0.317	NA	0.318	NA	0.326	6.9e-09	NA	6.3e-09	NA	3.7e-09
4	GTEx	Brain Cerebellum	0.3740	0.1050	5.2e-04	0.249	NA	0.240	NA	0.256	5.5e-08	NA	1.0e-07	NA	3.5e-08
5	GTEx	Esophagus Gastroesophageal Junction	0.2390	0.0940	8.8e-03	-0.008	NA	0.006	NA	-0.001	8.8e-01	NA	1.9e-01	NA	3.4e-01
6	GTEx	Nerve Tibial	0.1164	0.0459	7.2e-03	0.052	NA	0.021	NA	0.033	1.4e-04	NA	1.2e-02	NA	2.1e-03
7	GTEx	Skin Sun Exposed Lower leg	0.1040	0.0380	1.6e-03	0.011	NA	0.035	NA	0.035	3.9e-02	NA	6.6e-04	NA	6.3e-04
8	METSIM	Adipose	0.1169	0.0319	2.1e-07	0.058	0.050	0.038	0.048	0.039	3.9e-09	4.9e-08	1.7e-06	1.1e-07	1.2e-06
9	ROSMAP	Brain Pre-frontal Cortex	0.0829	0.0262	1.0e-04	0.052	0.034	0.031	0.035	0.040	3.0e-07	2.7e-05	6.5e-05	2.5e-05	6.5e-06
10	TCGA	Glioblastoma Multiforme	0.1040	0.0600	9.2e-03	0.007	0.004	-0.002	NA	0.023	1.9e-01	2.4e-01	3.7e-01	NA	6.7e-02
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0616	0.0313	1.0e-04	0.046	0.035	0.031	NA	0.039	6.1e-06	6.8e-05	1.7e-04	NA	3.1e-05
12	TCGA	Thyroid Carcinoma	0.0270	0.0160	6.5e-03	0.025	0.029	0.030	NA	0.030	1.6e-03	7.7e-04	6.5e-04	NA	5.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Migraine (self-reported)	7.4	9.2	16.9	3.4	2.9	3.1	3.4	4.1	2.7	2.3	1.2	3.3	3.2	3.2	2.7
Birth weight	6.9	15.0	27.0	-2.9	-4.3	-4.0	-3.2	-1.8	-4.2	-3.6	-5.2	-3.8	-4.3	-3.8	-4.3
Heel bone mineral density (BMD) T-score, automated (right)	5.2	12.0	18.1	2.7	3.8	3.6	3.0	2.0	3.9	4.3	3.0	3.4	3.7	3.5	4.0
Comparative height size at age 10	5.1	28.1	56.7	-2.0	-5.5	-4.5	-4.6	-0.7	-5.7	-7.5	-6.9	-4.8	-7.4	-4.8	-5.0
Number of children fathered	4.6	5.2	8.8	1.6	2.5	2.4	2.2	0.0	2.3	2.6	2.2	2.4	3.0	2.3	2.4
Systolic Blood Pressure	4.5	22.6	54.0	6.1	4.6	4.0	4.3	7.3	4.8	4.8	1.8	4.6	4.0	4.2	4.5
Depression (self-reported)	4.4	5.2	8.6	1.8	2.5	2.1	2.8	2.4	2.9	2.5	0.8	2.4	2.1	2.1	2.5
Commuting to job workplace: Public transport	4.3	5.1	6.3	-2.2	-2.5	-2.4	-2.2	-2.5	-2.5	-1.6	-2.0	-2.2	-2.4	-2.5	-2.1
Heel bone mineral density (BMD) T-score, automated (left)	4.2	9.6	15.7	1.9	3.4	3.2	2.7	1.5	3.7	4.0	2.7	3.0	3.5	3.0	3.7
Asthma	4.2	8.2	13.0	-3.2	-3.2	-2.7	-3.2	-3.2	-3.6	-2.5	-0.6	-3.1	-2.0	-2.8	-3.0
Waist circumference	4.1	15.2	30.4	-2.3	-4.1	-3.1	-3.8	-1.8	-4.0	-5.5	-4.6	-3.8	-4.8	-3.8	-3.5
Bipolar Disorder (2018)	3.9	6.1	10.7	2.1	2.6	2.0	2.6	1.5	3.3	3.0	2.8	2.5	2.0	2.1	2.8
Weight	3.8	18.7	37.6	-1.7	-4.5	-3.5	-3.9	-0.6	-4.2	-6.0	-5.8	-3.9	-6.1	-4.2	-4.0
Hair/balding pattern: Pattern 3	3.8	5.6	10.5	2.8	2.4	2.1	2.6	2.0	2.6	3.2	1.1	2.4	1.6	2.1	2.7
Age when periods started (menarche)	3.6	8.7	12.3	2.7	3.1	2.9	3.3	1.0	3.5	3.0	3.5	3.2	2.6	2.8	3.0
Basal metabolic rate	3.6	19.9	45.2	-0.9	-4.7	-3.7	-3.8	1.0	-4.2	-5.9	-6.2	-3.9	-6.7	-4.2	-4.2
Trunk fat-free mass	3.5	20.0	48.9	-0.6	-4.6	-3.7	-3.8	1.5	-4.2	-5.7	-6.2	-3.8	-7.0	-4.1	-4.2
Asthma (self-reported)	3.5	7.0	11.4	-3.0	-3.0	-2.6	-3.0	-3.0	-3.4	-2.1	-0.2	-2.9	-1.7	-2.5	-2.7
LDL Cholesterol	3.4	5.3	8.4	-2.6	-2.4	-2.4	-2.5	-1.9	-2.0	-2.2	-1.2	-2.5	-2.9	-2.4	-2.2
Stomach or abdominal pain in last month	3.4	4.2	6.1	1.7	2.2	1.8	2.1	1.8	2.4	2.1	2.5	1.8	1.8	1.9	2.3
Trunk predicted mass	3.4	19.6	47.9	-0.7	-4.6	-3.7	-3.7	1.5	-4.2	-5.6	-6.3	-3.8	-6.9	-4.0	-4.2
Deep venous thrombosis (DVT) (self-reported)	3.4	4.3	6.6	-2.4	-2.2	-2.0	-2.5	-1.8	-2.3	-1.6	-1.1	-2.3	-1.7	-2.1	-2.6
Heel T-Score	3.3	26.2	65.1	1.9	5.4	4.6	3.9	0.7	5.7	8.1	6.1	4.4	6.2	4.8	5.5
Standing height	3.3	32.5	72.1	-1.8	-5.8	-4.8	-4.1	0.2	-5.7	-8.2	-8.0	-4.9	-8.5	-5.0	-5.3
Whole body fat-free mass	3.3	18.8	44.6	-0.6	-4.5	-3.6	-3.7	1.4	-4.1	-5.5	-6.1	-3.7	-6.7	-4.0	-4.1
Whole body water mass	3.3	18.9	44.9	-0.6	-4.5	-3.6	-3.6	1.4	-4.1	-5.6	-6.2	-3.7	-6.7	-4.0	-4.1
Ulcerative Colitis	3.1	4.6	6.9	2.0	2.2	2.2	1.9	0.0	2.2	1.9	2.5	2.3	2.6	2.2	2.2
Lung FEV1/FVC ratio	3.1	15.7	25.7	-3.2	-4.5	-3.9	-3.2	-2.7	-4.0	-4.4	-2.9	-3.8	-4.7	-4.4	-5.1
Leg fat-free mass (left)	3.1	16.7	35.0	-1.2	-4.4	-3.5	-3.6	0.8	-4.0	-5.1	-5.7	-3.7	-5.9	-3.9	-4.0
Leg predicted mass (left)	3.1	16.5	34.8	-1.1	-4.3	-3.4	-3.5	0.9	-3.9	-5.1	-5.7	-3.6	-5.9	-3.9	-4.0
Allergy	3.1	7.0	12.1	3.5	2.8	2.5	2.9	3.2	3.0	2.1	0.7	2.9	2.1	2.5	2.7
Whole body fat mass	3.1	12.9	28.8	-2.1	-3.7	-2.8	-3.3	-1.7	-3.5	-5.4	-4.3	-3.3	-4.7	-3.5	-3.2
Ulcerative Colitis (UC)	3.0	5.7	10.2	2.3	2.5	2.1	1.6	2.4	2.5	1.9	3.2	2.2	2.3	2.3	2.9
Average weekly spirits intake	3.0	3.8	9.2	-1.6	-1.8	-2.2	-2.7	-0.2	-1.2	-1.5	-1.4	-2.0	-3.0	-2.2	-1.8
Systolic blood pressure, automated reading	3.0	8.6	24.0	3.8	2.7	2.5	2.7	4.9	2.8	2.8	0.6	2.9	2.2	2.4	2.8
Trunk fat mass	3.0	13.0	31.2	-2.0	-3.7	-2.7	-3.1	-1.9	-3.5	-5.6	-4.4	-3.2	-4.7	-3.4	-3.3
Arm fat mass (right)	3.0	12.5	21.2	-2.3	-3.8	-3.0	-3.3	-2.0	-3.5	-4.6	-4.2	-3.4	-4.5	-3.6	-3.4
Knee pain experienced in last month	3.0	4.6	7.9	-2.2	-2.3	-1.9	-2.4	-2.8	-2.8	-2.1	-0.7	-1.9	-1.5	-1.9	-2.4
Arm predicted mass (left)	3.0	15.2	37.2	-0.1	-4.0	-2.9	-3.1	1.7	-3.5	-5.4	-5.6	-3.2	-6.1	-3.5	-3.5
Height	2.9	55.2	134.6	-2.3	-7.2	-6.4	-5.5	1.0	-6.3	-9.8	-11.5	-6.9	-11.6	-6.9	-6.2
Health satisfaction	2.9	3.8	6.9	1.4	2.1	1.8	1.5	2.6	2.0	2.4	1.5	1.9	1.9	1.8	2.1
Medication: Blood pressure	2.9	5.0	8.6	2.9	2.3	2.4	2.2	1.9	2.2	2.7	1.1	2.4	2.0	2.4	2.1
Arm fat-free mass (left)	2.9	14.5	35.8	0.1	-3.8	-2.8	-3.1	1.9	-3.4	-5.3	-5.6	-3.0	-6.0	-3.4	-3.4
Arm fat-free mass (right)	2.8	14.5	37.1	0.1	-3.8	-2.9	-3.0	2.2	-3.3	-5.2	-5.5	-3.0	-6.1	-3.4	-3.4
Shortness of breath walking on level ground	2.8	3.4	10.0	1.8	1.8	1.9	0.9	3.2	1.7	2.0	0.4	1.4	1.5	1.8	2.2
Leg fat-free mass (right)	2.8	15.2	32.6	-0.9	-4.1	-3.3	-3.4	0.9	-3.6	-5.0	-5.6	-3.5	-5.7	-3.7	-3.8
Leg predicted mass (right)	2.8	14.8	31.8	-0.8	-4.1	-3.2	-3.3	0.9	-3.6	-4.9	-5.5	-3.4	-5.6	-3.7	-3.7
Arm fat mass (left)	2.8	11.3	20.0	-2.1	-3.5	-2.8	-3.3	-1.6	-3.2	-4.5	-4.1	-3.2	-4.4	-3.4	-3.2
Frequency of depressed mood in last 2 weeks	2.6	3.6	12.9	1.4	2.0	1.3	1.2	3.6	2.4	1.3	0.4	1.6	1.3	1.5	2.7
Arm predicted mass (right)	2.6	13.2	33.5	0.2	-3.5	-2.6	-2.8	2.4	-3.1	-5.2	-5.3	-2.7	-5.8	-3.1	-3.1
Blood clot in the leg (DVT)	2.5	3.2	5.3	-2.1	-1.9	-1.8	-2.2	-1.3	-1.9	-1.2	-0.9	-2.0	-1.4	-1.8	-2.3
Maternal smoking around birth	2.4	3.5	8.3	-2.0	-1.6	-2.3	-2.9	-1.0	-0.9	-1.1	-1.3	-2.3	-2.5	-2.3	-0.8
Osteoarthritis (self-reported)	2.4	3.1	4.8	-1.6	-2.0	-2.0	-1.8	-1.4	-1.8	-1.8	-1.0	-1.6	-1.7	-2.0	-2.2
Guilty feelings	2.4	3.5	9.7	2.0	1.8	1.5	1.5	3.1	1.8	2.3	-0.6	1.8	1.5	1.7	2.0
Alcohol usually taken with meals	2.3	3.8	6.1	-1.6	-2.3	-1.9	-1.5	-1.9	-2.4	-2.5	-1.7	-1.7	-1.4	-1.9	-2.2
Hip circumference	2.3	10.1	23.0	-1.4	-3.1	-2.4	-3.2	-0.8	-2.7	-4.4	-4.0	-3.1	-4.8	-3.2	-2.7
Medication: Ventolin 100micrograms inhaler	2.2	2.8	4.5	-2.1	-2.0	-1.7	-1.7	-1.5	-2.1	-1.6	-0.8	-1.8	-0.8	-1.6	-1.7
Leg fat mass (right)	2.2	8.4	20.8	-1.5	-3.0	-2.1	-2.7	-0.7	-2.9	-4.6	-3.6	-2.6	-3.9	-2.8	-2.6
Forced expiratory volume in 1-second (FEV1), predicted	2.2	4.5	9.3	-0.4	-2.2	-1.7	-1.8	0.6	-2.2	-2.8	-3.0	-1.9	-3.0	-1.8	-2.3
Ever taken oral contraceptive pill	2.2	2.4	3.6	1.7	1.5	1.2	1.6	0.4	1.8	1.8	1.9	1.8	1.4	1.3	1.6
Leg fat mass (left)	2.2	8.5	21.6	-1.4	-2.9	-2.1	-2.7	-0.8	-2.8	-4.7	-3.6	-2.6	-4.0	-2.8	-2.5
Respiratory disease	2.1	4.6	8.4	-2.7	-2.4	-1.9	-2.5	-2.5	-2.9	-1.8	0.1	-2.5	-1.2	-1.9	-1.9
Falls in the last year	2.0	2.7	6.4	-1.6	-1.3	-1.3	-1.5	-1.4	-1.2	-1.9	-2.5	-1.9	-2.3	-1.3	-1.0
Trunk fat percentage	1.9	7.5	19.7	-2.0	-2.7	-2.0	-2.4	-2.4	-2.6	-4.4	-2.9	-2.4	-3.1	-2.6	-2.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.0	11.7	-0.8	-2.7	-2.5	-1.8	0.3	-2.5	-3.4	-3.1	-2.3	-3.2	-2.4	-2.3
Chronic bronchitis/emphysema (mother)	1.9	2.2	4.0	-1.6	-1.6	-1.8	-2.0	-1.2	-1.3	-1.1	-0.9	-1.8	-1.3	-1.7	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	4.6	-1.8	-1.5	-1.9	-2.1	-1.1	-1.2	-0.0	-0.3	-1.7	-1.8	-1.6	-1.0
Osteoporosis (self-reported)	1.9	2.4	6.1	-2.2	-1.5	-1.5	-1.4	-2.5	-1.2	-1.5	0.3	-1.5	-0.6	-1.6	-1.5
Supplements: Zinc	1.8	1.9	3.2	1.8	1.1	1.4	1.5	1.8	0.8	1.6	0.8	1.3	1.2	1.5	1.5
Illnesses of siblings	1.8	2.5	4.7	-2.2	-1.3	-1.4	-1.8	-1.6	-1.0	-2.0	-1.5	-1.5	-1.4	-1.6	-1.2
Arm fat percentage (right)	1.8	6.9	10.0	-2.5	-2.7	-2.1	-2.5	-3.1	-2.6	-3.2	-2.4	-2.5	-2.6	-2.6	-2.4
Worrier / anxious feelings	1.8	3.4	8.8	2.0	1.6	1.1	1.5	2.4	1.9	3.0	0.9	1.7	1.7	1.4	2.0
Number of incorrect matches in round	1.7	2.9	5.4	-1.8	-2.0	-1.8	-1.4	-1.2	-2.3	-1.4	-1.0	-1.7	-1.6	-1.7	-2.0
Friendships satisfaction	1.7	2.1	6.3	1.7	1.3	1.1	1.3	2.5	1.2	1.8	1.3	1.4	1.3	1.1	1.0
Blood White Count	1.6	12.0	29.7	-2.2	-3.4	-3.2	-2.8	-0.1	-3.3	-5.5	-4.5	-3.3	-4.3	-3.4	-2.9
BMI	1.6	9.3	16.6	-2.1	-3.3	-2.7	-3.2	-1.4	-2.9	-4.1	-2.8	-3.1	-3.7	-3.4	-2.9
Hayfever, allergic rhinitis or eczema	1.6	3.4	8.4	-2.9	-1.8	-1.6	-1.8	-2.4	-1.7	-1.6	-1.0	-1.9	-1.6	-1.6	-1.5
Body fat percentage	1.6	6.4	16.4	-1.9	-2.5	-1.8	-2.3	-2.3	-2.5	-4.0	-2.5	-2.3	-2.8	-2.5	-2.2
Medication: Aspirin	1.6	2.1	3.2	1.4	1.4	1.8	1.2	1.1	1.1	1.3	1.6	1.7	1.5	1.8	1.2
Mother’s age at death	1.6	1.9	4.4	0.8	1.2	1.1	1.3	0.1	1.0	2.1	2.0	1.3	1.9	1.3	1.3
Bipolar Disorder or Schizophrenia	1.5	3.7	6.1	1.6	2.2	1.8	2.3	0.6	2.1	2.5	0.9	2.2	1.9	2.0	2.3
Blood Eosinophil Count	1.5	11.7	19.3	-3.6	-3.5	-3.5	-4.4	-2.5	-3.4	-3.9	-1.5	-3.5	-3.7	-3.4	-3.3
Waist Hip Ratio (WHR)	1.5	6.7	18.4	-1.7	-2.9	-2.2	-2.4	-1.4	-3.3	-4.3	-1.8	-2.6	-2.1	-2.3	-2.9
Nervous feelings	1.5	2.7	6.5	1.5	1.6	1.2	0.9	2.3	1.8	1.7	1.4	1.0	1.6	1.4	2.6
Length of working week for main job	1.5	1.7	2.7	-1.0	-1.4	-1.1	-1.3	-1.2	-1.6	-1.4	-1.1	-1.3	-1.4	-1.1	-1.6
Suffer from ‘nerves’	1.5	2.4	4.8	1.4	1.5	0.9	0.9	1.9	2.1	1.6	2.2	1.0	1.0	1.0	2.0
Had major operations	1.5	1.7	4.7	-1.4	-1.2	-1.2	-2.2	-1.6	-0.8	-0.8	-1.1	-1.2	-1.4	-1.4	-0.9
Arm fat percentage (left)	1.5	6.0	9.1	-2.4	-2.5	-1.9	-2.5	-2.8	-2.4	-3.0	-2.2	-2.4	-2.5	-2.5	-2.2
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	3.5	-1.9	-1.5	-1.6	-1.7	-1.7	-1.3	-0.9	0.7	-1.3	-0.9	-1.5	-0.9
Irritable Bowel Disease (IBD)	1.4	3.3	10.6	2.1	1.9	1.7	1.1	3.3	2.0	1.1	1.1	1.6	1.0	1.7	2.1
Breast cancer (self-reported)	1.4	1.6	3.2	-1.7	-1.3	-1.4	-0.9	-0.9	-1.1	-1.2	-0.7	-1.3	-1.3	-1.3	-1.8
Depression (Nagel 2018)	1.3	1.9	8.1	0.3	1.5	0.8	0.4	2.9	1.9	0.9	0.3	1.0	0.9	0.9	2.1
Loud music exposure frequency	1.3	1.4	4.7	0.8	1.2	0.7	0.5	2.0	1.8	0.5	0.4	1.0	0.4	0.7	2.2
Diastolic blood pressure, automated reading	1.3	4.1	25.5	2.6	1.2	0.9	1.4	5.1	1.4	1.8	0.5	1.5	1.2	1.0	1.4
Breast Cancer	1.2	2.8	5.8	2.2	1.8	1.4	1.7	2.4	1.9	1.1	0.7	1.4	1.3	1.5	1.9
Hypothyroidism (self reported)	1.2	2.8	7.6	-1.0	-1.7	-1.6	-1.1	0.8	-1.9	-0.9	-2.8	-1.8	-1.8	-1.5	-2.2
Type 2 Diabetes (T2D) (2018)	1.2	2.2	3.5	1.3	1.7	1.6	0.9	1.3	1.6	1.9	1.4	1.2	1.5	1.6	1.4
High blood pressure	1.2	3.5	13.8	1.5	1.6	0.9	1.2	3.7	2.2	2.8	1.0	1.3	1.3	1.2	1.6
Medication: Ramipril	1.2	1.5	3.2	1.1	1.4	1.0	1.1	1.8	1.7	1.6	0.3	1.1	0.7	1.2	1.0
Forced vital capacity (FVC), Best measure	1.2	4.3	9.3	-0.4	-2.1	-2.1	-1.6	0.7	-2.1	-3.0	-2.9	-1.9	-2.7	-1.9	-1.7
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	2.8	1.5	1.0	1.0	1.4	0.4	0.9	1.2	1.7	1.3	0.9	1.1	1.0
Happiness	1.1	1.3	2.7	-0.7	-1.2	-1.7	-1.3	0.9	-0.9	-0.4	-1.1	-1.2	-1.3	-1.6	-1.1
Tense / ‘highly strung’	1.1	1.8	4.9	0.3	1.3	1.0	0.5	2.2	1.3	1.4	1.4	0.9	1.3	1.3	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	2.7	1.6	1.4	1.3	1.1	1.3	1.2	1.7	-0.1	1.3	1.0	1.4	1.7
Birth weight of first child	1.1	1.9	7.2	-0.2	-1.3	-1.4	-0.7	-0.4	-1.4	-0.8	-2.7	-1.2	-1.6	-1.4	-1.7
Medication: Amlodipine	1.1	1.6	2.2	-1.4	-1.3	-1.4	-1.5	-0.2	-1.0	-1.2	-1.2	-1.5	-1.5	-1.4	-1.0
Hypertension (Self-reported)	1.1	3.2	12.7	1.6	1.5	0.8	1.0	3.6	2.0	2.9	1.0	1.2	1.1	1.1	1.5
Financial situation satisfaction	1.1	1.4	6.2	0.9	1.1	0.8	0.5	2.5	1.3	1.4	-0.0	0.5	0.9	0.7	1.6
Pain type(s) experienced in last month: Hip pain	1.1	1.4	2.9	-0.8	-1.2	-0.9	-1.3	-1.2	-1.3	-1.7	-1.4	-1.0	-0.7	-1.1	-1.1
Irritability	1.1	1.8	4.2	-0.9	-1.3	-1.7	-1.6	-0.5	-1.0	-0.4	-1.7	-1.4	-2.1	-1.6	-0.8
Ovarian Cancer	1.0	1.3	3.3	-1.8	-1.1	-1.3	-0.8	-1.7	-0.8	-0.3	-0.8	-1.1	-0.9	-1.2	-1.1
Blood Platelet Count	1.0	11.4	20.6	-4.5	-3.0	-3.2	-3.4	-4.5	-3.0	-3.3	-1.7	-3.5	-3.3	-3.6	-2.5
Cardiovascular Disease	1.0	3.3	18.7	1.9	1.3	0.5	0.6	4.3	1.8	2.7	0.4	0.9	0.8	0.8	1.4
Body mass index (BMI)	1.0	4.1	6.8	-1.1	-2.2	-1.6	-2.3	-0.7	-1.9	-2.6	-2.4	-1.9	-2.6	-2.2	-1.9
Diabetes (self-reported)	1.0	1.5	2.5	0.7	1.4	1.5	0.7	0.5	1.1	1.5	1.3	1.2	1.6	1.5	1.3
Number of live births	1.0	1.4	4.7	0.1	1.2	1.2	1.0	-1.0	0.7	0.7	1.2	1.2	2.2	1.5	1.1
Noisy workplace	1.0	1.3	3.1	1.5	1.1	0.9	1.2	1.8	1.5	0.9	-0.8	1.1	-0.0	0.8	1.1
Worry too long after embarrassment	1.0	1.6	9.1	0.2	1.0	0.7	0.3	3.0	1.1	0.8	1.2	0.6	1.5	0.8	1.5
Family relationship satisfaction	1.0	1.2	2.6	1.3	1.3	0.8	1.1	1.1	1.3	1.6	0.2	1.1	0.6	0.9	1.2
Average weekly champagne plus white wine intake	1.0	1.3	2.4	-1.6	-1.5	-1.3	-0.7	-1.5	-1.3	-0.8	-0.2	-0.9	-1.4	-1.1	-0.9
High cholesterol (Self-reported)	1.0	1.7	3.2	-1.1	-1.3	-1.2	-1.5	-1.8	-1.3	-0.4	-0.9	-1.3	-1.4	-1.2	-1.8
Worry (Nagel 2018)	0.9	1.9	8.3	1.2	1.2	0.8	0.6	2.9	1.3	2.0	0.7	0.9	0.7	1.0	1.6
Crohns Disease (2012)	0.9	1.5	7.3	1.5	0.8	0.9	0.9	2.7	0.8	0.7	-1.5	1.2	0.7	0.9	0.2
Mean Putamen Volume	0.9	1.0	2.5	0.7	0.9	1.5	1.0	1.1	0.2	0.2	-0.3	1.2	1.6	1.3	0.7
Rheumatoid Arthritis	0.9	1.2	2.4	-1.4	-1.2	-1.2	-0.7	-0.7	-1.1	-0.6	-1.1	-1.2	-1.6	-1.3	-0.8
Pain all over the body in last month	0.9	0.9	2.0	1.2	1.0	0.7	0.5	1.4	1.3	0.9	0.8	1.0	0.5	0.6	1.2
Medication: Omeprazole	0.9	1.1	1.9	-1.3	-1.1	-1.4	-1.4	-1.0	-0.8	-0.4	1.2	-0.9	-1.0	-1.2	-0.6
Medication: Seretide 50 evohaler	0.9	1.1	2.1	-1.4	-1.1	-0.8	-1.1	-1.2	-1.4	-1.0	-0.0	-0.9	0.0	-0.8	-1.5
Qualifications: nursing, teaching	0.9	1.4	3.0	0.9	1.1	1.1	1.3	1.3	1.0	1.7	1.1	1.0	1.2	1.0	1.1
Wears glasses or contact lenses	0.9	1.0	3.6	-1.5	-0.8	-0.6	-0.6	-1.9	-1.2	-0.7	-0.7	-0.4	-0.2	-0.5	-1.5
Medication: Atorvastatin	0.9	1.1	3.4	1.1	0.9	1.3	1.2	-0.3	0.7	0.4	1.0	1.2	1.9	1.2	0.7
Vascular/heart problems diagnosed by doctor	0.9	2.4	12.9	-1.2	-1.2	-0.5	-0.8	-3.6	-1.8	-2.2	-0.4	-0.9	-0.8	-0.8	-1.3
Neuroticism (Nagel 2018)	0.8	1.9	13.4	0.6	0.7	0.1	0.1	3.7	1.0	1.4	-1.7	0.4	-0.3	0.3	1.4
Neuroticism	0.8	1.8	13.1	1.0	0.6	0.2	0.5	3.6	0.7	1.2	-1.9	0.6	0.2	0.5	0.9
Sensitivity / hurt feelings	0.8	1.4	5.3	-1.1	-1.1	-1.5	-1.0	0.8	-0.8	0.3	-2.3	-1.4	-1.1	-1.2	-0.4
Ever used hormone-replacement therapy (HRT)	0.8	1.0	2.7	0.8	0.8	0.8	0.7	0.7	1.0	1.3	1.7	0.9	1.2	0.9	0.9
Ever had hysterectomy (womb removed)	0.8	0.9	2.0	-0.2	-1.1	-0.8	-1.4	0.2	-1.4	-0.6	-1.1	-1.3	-0.6	-0.8	-0.9
Medication: Levothyroxine sodium	0.8	1.4	2.7	-0.7	-1.2	-1.1	-0.7	0.8	-1.4	-1.0	-1.6	-1.5	-1.0	-1.0	-1.6
Chronic bronchitis/emphysema (father)	0.8	1.0	2.5	0.7	1.0	1.1	0.2	-0.1	0.7	1.3	1.6	0.7	1.4	1.0	0.9
High blood pressure (siblings)	0.8	1.2	3.1	1.2	0.7	0.9	1.2	0.7	0.6	1.8	1.3	1.1	1.0	1.2	0.8
Leg fat percentage (right)	0.8	2.8	10.2	-1.1	-1.6	-0.9	-1.6	-1.1	-1.7	-3.2	-1.6	-1.4	-1.9	-1.6	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	3.7	0.4	0.9	0.7	1.0	0.1	0.8	1.9	1.0	0.8	1.0	1.0	1.0
Supplements: Vitamin C	0.8	1.0	3.5	-0.8	-1.2	-1.2	-0.5	-0.7	-1.4	-0.1	-0.8	-0.7	-0.5	-1.0	-1.9
Illnesses of father: Heart disease	0.8	1.1	4.1	-0.4	-1.1	-1.1	-0.7	0.1	-0.9	-2.0	-1.1	-1.0	-0.8	-1.2	-1.1
Mood swings	0.8	1.5	10.6	1.3	0.2	0.1	0.5	3.3	0.3	0.9	-1.6	0.6	-0.3	0.4	0.8
Eye problems/disorders: Cataract	0.8	0.9	2.3	0.5	1.2	0.8	1.0	0.2	1.5	1.3	0.8	0.8	0.8	0.9	1.0
Tinnitus: Yes, now most or all of the time	0.8	1.0	2.7	-0.3	-0.7	-1.3	-1.3	-0.6	-0.2	-0.7	-1.3	-0.8	-1.7	-1.3	-0.8
Number of operations (self-reported)	0.8	1.1	2.5	-1.0	-1.1	-1.2	-1.6	-1.5	-0.7	0.0	-0.6	-0.8	-1.0	-1.1	-1.0
Depressed Affect (Nagel 2018)	0.7	1.6	10.4	0.7	0.3	-0.0	0.1	3.2	0.4	0.4	-2.5	0.4	-0.8	0.1	0.5
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.6	0.5	0.7	0.9	0.5	-0.2	0.7	0.3	1.6	0.8	1.0	0.9	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.9	-0.1	1.0	0.2	-0.0	2.0	1.4	0.6	-0.0	0.5	0.2	0.3	1.7
Serious illness, injury or assault to yourself	0.7	0.8	2.0	-0.8	-0.8	-0.7	-0.9	-0.5	-0.9	-1.4	-0.6	-0.9	-1.2	-0.6	-1.0
Sitting height	0.7	5.0	14.7	1.8	-1.4	-0.8	-0.9	2.6	-1.6	-3.8	-3.5	-0.7	-3.7	-0.9	-1.5
Hair/balding pattern: Pattern 2	0.7	0.9	1.3	-0.9	-1.0	-0.8	-1.1	-0.4	-1.0	-1.1	-0.3	-1.0	-1.1	-0.8	-1.1
Medication: Simvastatin	0.7	1.1	2.4	-0.7	-0.7	-0.8	-1.6	-1.3	-1.0	0.0	-1.3	-1.0	-1.3	-0.8	-1.1
Hair/balding pattern: Pattern 4	0.7	1.8	3.5	1.6	1.3	1.2	1.5	1.9	1.5	0.8	0.7	1.3	1.2	1.2	1.4
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	5.2	-0.7	-1.0	-0.9	-0.5	1.1	-1.3	-0.3	-2.3	-1.3	-1.2	-0.7	-1.6
Pulse wave peak to peak time	0.7	0.8	2.8	-1.1	-0.6	-0.5	-0.6	-0.6	-0.7	-1.7	-0.8	-0.9	-0.4	-0.7	-1.1
Alcohol intake frequency.	0.7	1.6	3.9	1.6	1.3	1.3	1.1	2.0	1.2	0.3	1.2	0.8	1.1	1.2	1.3
Age at last live birth	0.7	1.0	2.0	-0.0	1.0	0.9	1.3	-0.6	0.8	0.9	1.4	0.9	1.2	1.0	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.4	-1.0	-0.7	-0.9	-0.6	-1.8	-0.4	-0.0	-0.6	-0.8	-1.2	-0.9	-0.7
Handedness (chirality/laterality): Left-handed	0.7	0.9	4.0	-1.2	-0.8	-0.6	-0.5	-2.0	-0.8	-1.1	-0.4	-0.7	-0.8	-0.7	-0.7
Leg fat percentage (left)	0.7	2.4	9.9	-0.9	-1.4	-0.7	-1.4	-1.1	-1.4	-3.1	-1.4	-1.3	-1.9	-1.4	-1.0
Basal cell carcinoma (self-reported)	0.7	0.9	2.2	-0.4	-0.9	-0.5	-1.0	-1.5	-1.4	-1.2	-0.8	-0.3	-0.1	-0.5	-1.4
Crohns Disease (2017)	0.6	1.4	9.1	1.5	0.5	0.6	0.2	3.0	0.5	-0.0	-1.8	0.6	-0.5	0.4	0.4
Allergy or Eczema	0.6	1.7	4.7	-2.2	-1.3	-0.8	-1.2	-1.9	-1.4	-1.0	-0.9	-1.3	-1.2	-0.8	-0.9
Hand grip strength (left)	0.6	1.7	11.0	1.3	-0.7	0.0	-0.3	1.6	-0.8	-3.3	-0.8	-0.1	-1.6	-0.4	-0.5
Hand grip strength (right)	0.6	1.5	8.8	1.4	-0.1	0.3	0.1	2.4	0.0	-3.0	0.0	0.2	-1.2	-0.1	-0.2
Average weekly fortified wine intake	0.6	0.7	1.9	-1.1	-0.9	-0.9	-1.0	-1.4	-0.8	-0.5	0.1	-0.6	-0.3	-0.8	-0.7
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	5.8	0.5	-0.2	-0.3	-0.3	2.4	-0.1	-0.3	-1.3	-0.4	-0.8	-0.4	-0.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	6.3	-0.8	-0.6	-0.4	-0.4	-2.5	-0.8	-0.2	-0.5	-0.9	-0.4	-0.5	-0.3
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	5.3	0.1	-1.5	-1.4	-0.8	0.9	-1.5	-2.3	-2.0	-1.2	-2.0	-1.3	-1.4
Pulse wave reflection index	0.6	0.8	1.9	1.3	0.6	0.6	0.9	0.9	0.6	0.9	1.4	0.8	0.4	0.6	1.2
Leg pain on walking	0.6	0.7	2.0	0.9	0.9	0.9	0.6	1.4	0.7	0.8	0.0	1.0	0.8	0.9	0.7
Ever had bowel cancer screening	0.6	0.7	1.4	0.2	0.9	0.9	0.9	-0.6	0.7	1.2	0.8	0.8	1.2	0.8	0.2
Medication: Gliclazide	0.6	0.6	1.4	-1.0	-0.7	-0.3	-0.6	-1.0	-0.8	-1.2	-0.9	-0.8	-0.8	-0.6	-0.5
Eye problems/disorders: Glaucoma	0.6	0.8	2.7	0.5	0.8	0.4	0.6	0.6	1.2	1.7	-0.0	0.8	0.7	0.6	1.3
Fractured/broken bones in last 5 years	0.6	0.7	2.2	-0.5	-0.7	-1.2	-0.8	0.8	-0.2	-0.3	-0.9	-0.8	-1.5	-1.1	-0.5
Age at First Birth	0.5	0.7	1.9	0.5	0.8	1.1	1.0	0.3	0.3	-0.0	0.6	1.0	1.4	1.2	0.8
Relative age of first facial hair	0.5	1.1	3.5	-1.9	-0.9	-1.2	-1.1	-0.9	-0.5	-0.4	-1.1	-1.2	-0.7	-1.1	-1.0
Townsend deprivation index at recruitment	0.5	0.8	2.7	-0.8	-0.7	-0.7	-1.0	-1.6	-0.7	-0.7	-0.9	-0.8	-0.7	-0.8	-0.5
Current tobacco smoking	0.5	0.8	1.5	-0.9	-0.7	-0.9	-1.2	-0.4	-0.5	-0.8	-1.1	-1.1	-1.2	-1.0	-0.5
Fed-up feelings	0.5	1.0	7.0	0.3	-0.2	-0.5	-0.6	2.6	0.0	-0.1	-1.7	-0.1	-0.8	-0.4	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.9	-0.1	0.4	-0.3	-0.5	1.7	1.0	1.5	0.6	0.2	-0.2	-0.1	1.4
Forced vital capacity (FVC)	0.5	1.9	5.9	0.5	-1.1	-1.2	-0.7	1.3	-1.3	-2.2	-2.4	-1.0	-1.7	-0.9	-0.9
Financial difficulties in last 2 years	0.5	0.6	3.2	-1.0	-0.7	-0.7	-0.7	-0.2	-0.7	-0.6	-1.8	-0.6	-0.5	-0.6	-0.5
Neuroticism score	0.5	1.1	7.6	0.8	0.6	0.1	0.3	2.8	0.8	1.4	-0.3	0.5	0.5	0.4	1.2
Medication: Lansoprazole	0.5	0.6	1.2	-0.2	1.0	0.9	0.7	-0.5	0.7	0.7	-0.2	0.6	1.0	1.0	1.1
Peak expiratory flow (PEF)	0.5	1.2	6.5	0.6	-1.0	-0.5	-1.0	0.3	-1.3	-2.5	-0.2	-0.7	-0.8	-0.7	-1.5
Medication: Paracetamol	0.5	0.8	4.3	-0.9	-0.8	-0.9	-0.5	-0.3	-0.7	-0.5	-2.1	-0.3	-0.7	-0.7	-1.0
Gout (self-reported)	0.5	0.7	2.1	-1.4	-0.5	-0.8	-1.3	-0.8	-0.2	0.1	0.0	-0.6	-1.2	-0.8	-0.4
Eye problems/disorders: None of the above	0.5	0.5	1.2	-0.4	-0.6	-0.5	-0.8	-0.1	-1.0	-0.7	-0.9	-0.7	-1.1	-0.5	-0.8
Mean time to correctly identify matches	0.5	1.0	7.5	-0.9	-0.7	-0.9	0.1	0.6	-0.4	-0.2	-2.7	-0.6	-1.0	-0.7	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.0	0.9	0.6	0.7	1.0	-0.6	0.4	0.7	0.5	1.0	0.9	0.8	0.4
Commuting to job workplace: Walk	0.5	0.5	4.2	0.0	-0.3	-0.4	-0.2	0.1	-0.5	0.3	-2.0	-0.4	-0.5	-0.3	-0.8
Medication: Aspirin	0.5	0.7	1.4	0.9	0.7	1.1	0.6	0.7	0.5	0.5	1.0	1.2	0.8	1.0	0.5
Number of self-reported non-cancer illnesses	0.5	0.9	1.6	-1.0	-1.0	-1.1	-1.3	0.0	-0.7	0.6	-0.9	-1.0	-0.9	-1.0	-1.0
Unable to work because of sickness or disability	0.5	0.7	2.1	-0.6	0.1	-0.5	-0.9	1.4	0.7	0.5	-1.5	-0.6	-1.1	-0.5	0.6
Pain experienced in last month	0.5	0.9	3.7	-0.4	-0.8	-0.4	0.0	-0.3	-1.1	-1.0	-1.9	-0.8	-1.3	-0.5	-1.0
Triglycerides	0.4	0.7	2.7	-0.9	-0.1	-0.7	-0.7	-1.0	0.1	1.6	1.0	-0.7	-0.7	-0.6	-0.1
Smoking Status	0.4	0.9	5.0	0.1	-0.1	-0.6	-0.4	1.1	0.4	0.5	-2.2	-0.4	-1.8	-0.5	0.3
Chronotype (morning person)	0.4	0.9	2.9	0.5	0.9	1.2	0.9	0.2	0.5	0.9	0.5	1.1	1.7	1.1	1.1
Hearing difficulty/problems: Yes	0.4	0.6	2.0	0.7	0.9	0.5	0.7	0.5	1.4	0.7	-0.1	0.7	0.8	0.6	0.9
Qualifications: CSEs or equivalent	0.4	0.5	3.3	1.0	0.4	0.5	0.9	1.8	0.1	-0.4	-0.2	0.2	0.1	0.6	0.6
Medication: Atenolol	0.4	0.5	1.4	0.9	0.3	0.0	0.6	1.2	0.5	0.5	-1.2	0.5	-0.7	0.3	0.3
Impedance of leg (left)	0.4	1.7	4.9	0.3	1.5	1.2	1.3	-0.9	1.1	-0.3	2.2	1.2	1.6	1.2	1.5
Had menopause	0.4	0.5	1.1	0.4	0.7	0.8	1.1	0.7	0.8	0.7	0.2	0.8	0.8	0.5	0.5
Heart attack	0.4	0.5	2.0	0.6	0.7	0.6	0.4	0.8	0.7	1.4	0.4	0.8	0.6	0.6	0.6
Impedance of arm (right)	0.4	2.0	14.1	-2.6	-0.3	-0.7	-0.0	-3.8	-0.7	-0.1	0.8	-0.8	0.9	-0.4	-0.4
Time employed in main current job	0.4	0.4	1.2	0.8	0.2	1.1	0.7	0.3	-0.6	0.0	0.4	0.7	0.8	1.0	0.0
Alcohol intake versus 10 years previously	0.4	0.5	1.9	0.6	-0.5	-0.3	-0.5	-0.3	-0.7	-1.4	-0.5	-0.6	-1.2	-0.3	-0.9
Mouth/teeth dental problems: Dentures	0.4	0.7	2.7	-0.9	-0.5	-0.5	-0.5	-1.3	-0.3	-0.7	-1.7	-0.5	-0.6	-0.5	-0.8
Medication: Cholesterol lowering	0.4	0.6	1.5	-0.6	-0.7	-0.5	-0.9	-0.7	-1.0	-0.0	-1.2	-0.5	-1.0	-0.5	-1.0
Pulse wave Arterial Stiffness index	0.4	0.5	2.0	1.1	0.4	0.3	0.6	0.7	0.4	1.4	0.2	0.7	-0.0	0.5	0.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.7	-1.1	-0.7	-0.8	-0.8	-1.0	-0.5	-1.3	0.9	-0.9	-0.2	-0.8	-0.5
Age at first live birth	0.4	0.8	3.5	0.2	0.6	0.6	0.9	-0.4	0.7	0.8	1.9	0.8	1.0	0.5	1.0
Emphysema/chronic bronchitis	0.4	0.5	1.1	-1.1	-0.6	-0.6	-0.8	0.0	-0.9	-0.2	-1.0	-0.9	-0.4	-0.6	-0.5
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.8	-0.0	0.3	0.5	-0.1	-0.7	-0.0	0.7	1.4	0.1	1.3	0.5	-0.1
Smoking status: Previous	0.4	0.7	1.5	1.2	0.6	0.3	0.9	0.6	0.9	1.0	-0.6	0.9	-0.8	0.6	0.9
Smoking status: Current	0.4	0.7	1.5	-0.9	-0.7	-0.8	-1.0	-0.4	-0.5	-0.9	-0.8	-1.0	-1.2	-1.0	-0.5
Miserableness	0.4	0.7	4.7	0.6	0.4	0.1	0.5	2.2	0.6	0.6	-0.7	0.4	0.1	0.3	1.2
Alcohol drinker status: Never	0.4	0.5	1.9	1.4	0.5	0.5	0.6	-0.0	0.7	0.4	1.4	0.8	-0.1	0.5	0.2
Average weekly beer plus cider intake	0.4	0.6	1.2	1.1	0.9	0.9	0.7	0.2	0.7	0.8	-0.2	0.9	0.7	1.0	0.8
Ever had prostate specific antigen (PSA) test	0.4	0.5	4.5	-0.2	-0.5	0.0	0.1	-2.1	-0.5	-0.3	0.7	0.1	-0.2	-0.0	-0.6
Ever depressed for a whole week	0.4	0.5	4.6	0.4	0.3	0.4	-0.0	2.2	0.5	0.2	-0.4	0.0	0.0	0.1	0.6
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.8	0.6	0.7	0.6	0.3	0.7	0.8	1.3	0.4	0.7	0.5	0.6	0.6
Schizophrenia vs Biploar Disorder	0.3	0.4	1.3	-0.1	-0.5	0.0	0.0	0.0	-1.0	-0.8	-1.1	-0.6	-0.5	-0.1	-1.1
Reaction Time	0.3	0.6	4.2	-0.8	-0.6	-0.7	0.1	0.6	-0.2	-0.2	-2.0	-0.4	-0.5	-0.5	-0.2
HbA1C	0.3	0.3	1.2	-0.1	0.7	0.4	0.6	1.0	1.1	0.8	0.0	0.4	-0.1	0.2	0.4
Schizophrenia (2014)	0.3	0.7	1.4	1.0	0.8	1.0	1.2	0.0	0.5	0.4	-1.1	0.9	0.6	0.9	1.0
Tanning	0.3	3.1	5.1	1.3	2.0	1.9	1.5	-0.7	2.2	1.6	2.1	1.6	1.9	1.8	1.9
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.9	-0.5	-0.5	-0.4	-1.0	-0.6	-0.3	-0.7	0.0	-0.6	-0.8	-0.5	-0.9
Angina	0.3	0.4	1.1	0.3	0.8	0.6	0.3	0.6	1.1	0.6	0.3	0.5	0.2	0.5	0.8
Medication: Metformin	0.3	0.5	1.8	-0.8	-0.5	-0.2	-0.7	-1.4	-0.6	-0.9	0.5	-0.5	-0.0	-0.4	-0.4
Pack years adult smoking proportion	0.3	0.4	1.4	-0.2	-0.0	-0.2	-0.8	1.2	0.2	-0.9	-1.1	-0.2	-0.7	-0.2	0.1
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.1	0.2	-0.8	-0.6	-0.4	-0.0	-0.8	0.1	-0.7	-0.4	-0.1	-0.4	-1.0
Multivitamins +/- minerals	0.3	0.4	1.2	0.8	0.4	0.4	0.7	1.1	0.4	0.6	-0.2	0.9	0.5	0.6	-0.1
High blood pressure (mother)	0.3	0.4	2.4	0.5	0.5	0.4	0.4	-0.1	0.4	1.6	-0.5	0.6	0.6	0.6	0.4
Hearing difficulty/problems with background noise	0.3	0.4	2.3	0.5	0.7	0.0	0.2	1.0	1.5	0.6	0.3	0.2	0.2	0.1	0.8
Pulse rate	0.3	0.5	1.8	-0.7	-0.3	-0.7	-1.3	-1.3	-0.3	0.1	0.5	-0.4	-0.4	-0.5	-0.6
Prospective memory result	0.3	0.3	2.8	-0.1	-0.2	0.2	0.6	-0.1	-0.5	0.4	-1.7	0.2	0.1	0.4	0.2
Lung cancer (father)	0.3	0.3	0.8	0.1	0.3	0.7	0.7	-0.7	-0.2	0.3	0.9	0.6	0.7	0.6	0.2
Impedance of arm (left)	0.3	1.6	11.4	-2.1	0.0	-0.3	0.3	-3.4	-0.2	0.2	1.1	-0.2	1.1	-0.1	-0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	1.4	0.3	0.4	0.5	0.6	-0.0	0.1	0.4	1.1	0.1	1.2	0.5	0.5
Comparative body size at age 10	0.3	0.8	2.1	-1.2	-0.9	-0.5	-1.0	0.2	-0.9	-1.2	-1.0	-0.6	-1.5	-0.7	-0.5
Angina (self-reported)	0.3	0.4	1.2	0.2	0.9	0.6	0.2	0.6	1.1	0.7	0.5	0.5	0.4	0.6	0.8
Number of full sisters	0.3	0.3	1.7	0.2	-0.3	0.1	0.2	-0.0	-0.7	-0.5	-1.3	-0.2	0.0	0.2	-1.0
Diabetes diagnosed by doctor	0.3	0.5	1.2	0.5	0.8	1.1	0.5	0.0	0.6	0.8	0.5	0.7	0.8	1.1	0.9
Back pain experienced in last month	0.3	0.4	0.9	-0.9	0.1	-0.3	-0.9	-0.7	0.8	0.4	0.9	0.0	0.1	-0.2	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.5	-0.0	-1.1	-0.8	-0.5	-0.2	-1.6	-0.8	-0.3	-0.6	-0.0	-0.7	-1.4
Hearing aid user	0.3	0.3	1.5	0.4	0.2	0.3	0.4	1.2	-0.2	-0.4	-1.2	0.2	0.1	0.5	-0.1
Supplements: Calcium	0.3	0.3	1.3	-0.7	-0.4	-0.6	-0.5	-1.1	0.1	-0.3	0.1	-0.2	-0.5	-0.6	-0.4
Heart disease (siblings)	0.3	0.4	1.2	1.1	0.4	0.1	0.8	1.0	0.5	0.9	0.1	0.2	-0.4	0.3	0.1
Pack years of smoking	0.3	0.4	1.8	0.0	0.2	0.1	-0.5	1.2	0.3	-0.9	-1.3	0.1	-0.6	0.1	0.3
Impedance of whole body	0.3	1.7	5.2	-0.9	1.1	0.7	1.2	-2.3	0.8	0.1	2.0	0.8	2.0	0.9	1.1
Schizophrenia (2018)	0.2	0.5	1.2	0.4	0.7	0.7	0.9	-0.3	0.1	0.6	-1.1	0.8	0.9	0.9	0.6
Alzheimer’s Disease (in father)	0.2	0.3	1.6	-0.0	-0.3	-0.5	-0.5	-1.3	-0.0	0.5	-0.1	-0.5	-0.2	-0.4	-0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.6	4.6	1.0	0.4	0.0	0.1	2.2	0.6	-0.0	0.1	0.6	0.5	0.2	0.1
Body Mass Index (BMI) (2010)	0.2	0.2	0.9	0.6	-0.3	0.2	0.1	1.0	-0.8	-0.1	-0.2	0.1	0.0	0.0	-0.6
HDL Cholesterol	0.2	0.4	1.8	-0.9	-0.7	-0.2	-0.3	-0.7	-0.7	-1.3	-0.5	-0.3	0.0	-0.4	-0.6
Lupus	0.2	0.2	2.2	0.2	-0.1	-0.1	0.1	0.5	-0.1	-0.2	-1.5	0.2	-0.4	-0.1	-0.3
Neuroticism (2016)	0.2	0.2	1.1	0.1	0.1	0.1	-0.1	0.9	-0.0	0.5	-1.1	-0.0	-0.0	0.2	0.6
Lung FVC	0.2	0.9	2.3	0.6	0.9	0.4	0.8	1.3	0.8	1.0	0.6	1.0	1.5	0.8	1.1
Hair Pigment	0.2	4.7	9.5	-1.5	-2.6	-2.1	-1.4	-1.8	-3.0	-2.4	-1.9	-1.9	-1.5	-2.0	-3.1
Vitamin and mineral supplements	0.2	0.2	1.1	-0.0	0.3	0.4	-0.3	-0.3	0.3	-0.8	0.7	-0.1	0.4	0.2	1.1
Impedance of leg (right)	0.2	1.0	3.2	-0.1	1.1	0.9	1.1	-0.8	0.6	-0.3	1.8	0.9	1.4	1.0	1.0
Supplements: Glucosamine	0.2	0.3	0.8	-0.6	-0.7	-0.6	-0.2	-0.3	-0.9	0.0	-0.8	-0.3	0.5	-0.2	-0.9
Past tobacco smoking	0.2	0.4	1.5	-0.6	-0.4	-0.0	-0.5	0.0	-0.8	-0.9	1.0	-0.5	1.2	-0.2	-0.7
Mouth/teeth dental problems	0.2	0.4	0.9	-0.4	-0.7	-0.6	-0.5	-0.4	-0.7	-0.6	-0.2	-0.4	-1.0	-0.7	-0.7
Fluid intelligence score	0.2	0.4	1.3	0.6	0.6	0.3	0.2	1.1	0.7	0.6	0.7	0.7	1.1	0.4	0.4
Father’s age at death	0.2	0.2	1.5	-0.1	0.1	0.1	-0.1	0.2	0.3	0.6	1.2	0.2	0.4	-0.0	0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	2.3	0.5	0.3	-0.2	0.1	1.5	0.5	0.3	1.0	0.2	0.7	0.0	0.4
Headache pain in last month	0.2	0.3	2.9	0.1	0.1	-0.1	-0.1	0.4	0.4	0.2	1.7	0.3	0.5	-0.2	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	2.2	0.5	0.4	0.0	-0.1	-0.1	0.6	1.5	-0.1	0.3	-0.3	0.1	0.7
Wheeze or whistling in the chest in last year	0.2	0.3	1.0	-0.9	-0.5	-0.6	-1.0	-0.1	-0.4	-0.1	0.3	-0.6	-0.1	-0.6	-0.3
Qualifications: College or University degree	0.2	0.5	2.2	-0.1	0.2	0.3	0.2	1.5	0.1	0.5	1.5	0.8	0.9	0.4	0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	2.0	0.1	0.1	-0.1	0.5	0.3	0.2	0.0	-1.4	0.1	-0.0	-0.1	0.1
Heart disease (mother)	0.2	0.3	1.9	0.1	-0.3	0.0	-0.1	-0.4	-0.4	-0.3	-1.4	-0.1	-0.2	-0.2	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.1	0.1	-0.2	0.6	0.1	-0.4	-1.0	-1.0	-0.5	-0.0	0.1	0.4	0.1
Pulse rate, automated reading	0.2	0.7	2.4	-1.5	-0.8	-1.0	-1.5	-0.5	-0.6	0.0	0.6	-0.6	-0.6	-0.9	-0.3
Chest pain or discomfort	0.2	0.2	1.5	0.9	0.2	0.3	0.2	-0.1	0.3	-0.0	1.2	0.1	0.3	0.2	0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.3	0.0	0.2	-0.1	0.9	0.1	0.5	1.1	0.1	0.3	0.3	-0.1	0.1
Illnesses of siblings: Diabetes	0.2	0.3	0.9	-0.5	-0.5	-0.3	-0.5	0.2	-0.8	-0.6	-0.2	-1.0	-0.4	-0.4	-0.4
Loneliness, isolation	0.2	0.3	1.1	-0.1	0.7	0.3	-0.1	0.7	0.6	0.8	-0.4	0.3	0.3	0.4	1.1
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.5	0.6	-0.0	0.3	-0.0	1.2	-0.4	0.0	0.5	0.3	1.1	0.4	-0.1
Medication: Blood pressure	0.2	0.5	1.0	-0.5	-0.3	-1.0	-0.9	0.7	0.2	0.7	-0.7	-0.8	-0.8	-0.9	-0.2
Medication: Bendroflumethiazide	0.2	0.2	1.0	1.0	0.4	0.1	0.2	0.3	0.5	0.8	0.1	0.3	-0.4	0.2	0.4
Ever smoked	0.2	0.3	1.1	0.5	0.3	0.0	0.5	0.3	0.6	0.8	-1.0	0.4	-1.1	0.1	0.3
Age started oral contraceptive pill	0.2	0.2	0.6	0.1	0.5	0.6	0.7	0.3	0.5	-0.1	-0.8	0.5	0.2	0.5	0.3
Commuting to job workplace: Cycle	0.2	0.2	0.7	-0.2	0.3	0.3	0.6	0.8	0.6	0.4	0.3	0.3	0.3	0.3	0.8
Myopia	0.2	0.2	0.7	0.4	0.5	0.6	0.4	0.8	0.1	0.4	-0.1	0.4	0.5	0.7	0.1
Intelligence (Savage-Jansen 2018)	0.1	0.2	1.1	0.2	-0.3	-0.3	-1.0	0.8	-0.1	-0.0	0.5	-0.4	0.2	-0.3	-0.5
Alzheimer’s Disease (in mother)	0.1	0.1	0.4	-0.5	-0.3	-0.1	0.1	0.1	-0.6	-0.3	-0.6	-0.1	-0.2	-0.2	-0.7
Alzheimer’s Disease (including proxy)	0.1	0.1	0.2	-0.3	-0.2	-0.2	-0.3	-0.1	-0.3	0.2	-0.3	-0.4	0.0	-0.3	-0.5
Prostate Cancer	0.1	0.2	0.4	-0.4	0.0	-0.7	-0.4	-0.3	0.3	0.6	-0.2	-0.4	-0.2	-0.5	-0.1
Fasting Glucose	0.1	0.1	0.2	0.1	0.4	0.3	0.0	0.0	0.4	0.2	0.4	0.1	0.2	0.2	0.2
Primary Biliary Cirrhosis	0.1	0.2	0.7	-0.1	-0.4	-0.2	-0.8	0.1	-0.3	-0.2	-0.5	-0.2	-0.4	-0.3	-0.4
Type 2 Diabetes (T2D) (2012)	0.1	0.2	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.7	0.5	0.6	0.7
Blood Red Count	0.1	1.1	5.8	1.5	0.1	0.4	-0.9	2.4	-0.1	-0.2	1.8	0.2	0.9	0.2	0.2
Number of treatments/medications taken	0.1	0.2	1.6	0.3	0.0	-0.1	-0.2	0.6	0.1	1.2	-0.7	0.2	0.2	-0.0	-0.0
Medication for hormone replacement therapy	0.1	0.1	1.1	0.0	-0.3	0.0	0.1	0.3	-0.2	0.0	1.0	-0.3	0.2	0.0	0.0
Diabetes (father)	0.1	0.1	0.5	0.3	-0.1	0.1	0.1	0.4	0.1	0.1	0.6	0.1	0.7	0.0	-0.2
Diabetes (mother)	0.1	0.1	0.3	0.3	-0.1	0.1	0.1	0.0	-0.4	0.6	-0.4	0.1	0.2	0.2	-0.3
Severe depression (siblings)	0.1	0.1	0.4	0.1	-0.0	-0.3	-0.0	-0.6	0.2	0.3	-0.4	-0.1	-0.7	-0.2	-0.2
Relative age voice broke	0.1	0.2	0.5	-0.5	0.6	0.2	0.3	0.1	0.7	0.4	-0.1	0.2	0.6	0.3	0.5
Taking other prescription medications	0.1	0.1	0.7	-0.0	-0.0	-0.2	-0.3	0.1	0.1	0.9	0.5	0.1	0.1	-0.0	0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.6	0.1	0.1	-0.0	-0.4	0.4	0.1	0.6	0.8	-0.1	-0.0	-0.1	-0.1
Had other major operations	0.1	0.1	0.5	-0.6	0.1	0.0	0.0	0.7	0.1	0.4	-0.3	-0.1	0.1	0.2	0.3
Qualifications: None of the above	0.1	0.3	2.3	0.3	-0.1	0.1	0.3	-0.5	-0.2	-0.4	-1.5	0.0	-0.3	-0.0	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.6	0.0	0.2	-0.3	-0.4	1.2	0.4	0.3	-0.1	-0.1	-0.0	-0.1	0.6
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.4	0.1	0.1	-0.2	-0.2	0.9	0.1	0.1	1.2	-0.2	0.4	-0.2	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.3	0.2	0.3	0.4	-0.2	0.1	0.0	-0.2	0.2	0.3	0.5	0.4	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.3	-0.2	-0.4	0.1	-0.1	0.6	-0.5	-0.3	0.1	0.4	0.4	-0.0	-0.3
Illnesses of mother	0.1	0.1	0.6	-0.4	0.0	-0.1	-0.3	0.5	0.2	-0.8	0.1	-0.4	-0.2	-0.2	0.4
Exposure to tobacco smoke at home	0.1	0.1	0.8	0.0	-0.1	0.1	-0.0	0.9	-0.2	-0.5	0.2	0.1	0.1	0.1	0.2
Breastfed as a baby	0.1	0.1	0.3	-0.1	-0.1	-0.4	0.1	-0.0	0.1	0.5	0.6	-0.0	0.2	-0.1	-0.4
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.6	-0.2	-0.2	-0.4	-0.3	0.8	0.3	-0.2	-0.2	-0.3	-0.3	-0.4	0.4
Glaucoma (self-reported)	0.1	0.1	0.6	-0.1	0.0	-0.3	-0.1	0.3	0.4	0.8	-0.8	-0.0	-0.0	-0.1	0.3
Exposure to tobacco smoke outside home	0.1	0.1	1.0	0.3	0.1	-0.0	0.1	1.0	-0.1	-0.5	0.4	0.1	-0.2	-0.1	-0.2
Number of full brothers	0.1	0.2	0.7	0.5	0.1	0.0	0.0	-0.8	-0.0	0.4	0.8	-0.3	0.3	0.0	-0.3
Medication for pain relief, constipation, heartburn	0.1	0.1	0.3	0.3	0.5	0.3	0.5	0.5	0.4	-0.2	0.3	-0.3	0.3	0.1	0.5
Neck or shoulder pain in last month	0.1	0.1	0.6	0.3	0.0	-0.2	-0.3	0.1	0.1	0.3	0.8	-0.1	0.3	-0.1	-0.1
Medication: Ibuprofen	0.1	0.1	0.3	-0.2	-0.5	-0.0	-0.2	0.3	-0.6	-0.3	-0.2	0.1	-0.1	-0.1	-0.4
Medication: Allopurinol	0.1	0.2	0.7	-0.8	0.0	0.2	-0.4	-0.8	-0.2	0.4	0.3	0.3	0.4	0.3	-0.2
Overall health rating	0.1	0.2	0.8	-0.2	0.4	0.4	-0.3	0.9	0.4	0.7	-0.2	0.2	-0.1	0.3	0.5
Long-standing illness, disability or infirmity	0.1	0.2	0.9	-0.6	-0.0	-0.1	-0.4	0.8	0.1	0.5	-1.0	-0.1	-0.1	-0.0	-0.1
Medication for cholesterol	0.1	0.1	0.4	0.0	0.3	0.4	0.7	0.2	0.1	-0.4	-0.2	0.5	0.1	0.3	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.4	0.1	-0.4	-0.3	-0.3	0.6	-0.3	-0.4	0.3	-0.3	-0.5	-0.4	-0.6
Mineral and other dietary supplements	0.1	0.2	0.7	-0.4	-0.4	-0.1	-0.5	-0.2	-0.6	-0.8	-0.1	-0.4	-0.3	-0.4	-0.1
Illnesses of father: None of the above (group 1)	0.1	0.1	0.5	-0.1	-0.1	0.1	0.3	-0.7	-0.2	-0.6	0.4	0.1	-0.2	0.1	-0.3
Medication: Paracetamol	0.1	0.2	2.1	-0.4	-0.3	-0.3	0.1	0.1	-0.0	-0.4	-1.5	0.2	-0.1	-0.1	-0.3
Medication: Lisinopril	0.1	0.2	1.2	0.1	0.2	-0.0	-0.5	1.1	0.4	0.3	0.1	-0.2	0.1	-0.1	0.1
Illnesses of father: High blood pressure	0.1	0.2	1.1	-0.5	-0.2	-0.2	-0.2	0.5	-0.4	0.4	-1.1	-0.1	0.1	-0.1	0.2
Risk taking	0.1	0.1	0.3	-0.3	-0.4	-0.0	-0.1	-0.3	-0.6	0.0	-0.3	-0.0	-0.2	-0.1	-0.5
Cholesterol lowering medication	0.1	0.1	0.9	-0.0	0.1	0.1	-0.3	-0.9	0.1	0.3	0.5	0.0	0.2	0.1	-0.4
Alcohol drinker status: Previous	0.1	0.1	0.4	-0.6	0.1	-0.0	-0.1	0.4	0.2	-0.4	-0.6	-0.2	0.1	0.1	0.4
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Medication: Co-codamol	0.0	0.0	0.2	-0.3	0.0	0.1	0.2	0.4	-0.1	-0.2	-0.2	0.2	0.2	0.1	-0.2
Average weekly red wine intake	0.0	0.1	0.3	0.1	-0.2	-0.3	0.2	-0.2	0.2	-0.2	-0.5	0.0	0.0	-0.2	0.1
Supplements: Fish oil (including cod liver oil)	0.0	0.1	0.3	0.0	-0.0	-0.4	-0.2	-0.0	0.1	0.6	0.3	-0.1	0.0	-0.0	-0.2

Hub : Genes

RNPS1

Models

Trait associations