[Hub]/) : Traits : Trunk fat-free mass : ← →

chr11:46,010,847-48,783,497

Best TWAS P=7.93e-16 · Best GWAS P=1.38e-14 conditioned to 0.0777

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
41	ROSMAP	Brain Pre-frontal Cortex	CELF1	0.03	0.01	bslmm	289	0.01	2.9e-02	6.5	8.1	7.9e-16	0.83	0.02	0.87	TRUE
21	GTEx	Skin Not Sun Exposed Suprapubic	LRP4	0.13	0.00	lasso	7	0.02	3.5e-02	6.0	7.6	3.8e-14	0.53	0.07	0.50	FALSE
43	ROSMAP	Brain Pre-frontal Cortex	C1QTNF4	0.05	0.06	blup	281	0.06	1.7e-08	-4.8	7.3	2.6e-13	0.65	0.98	0.02	FALSE
20	GTEx	Prostate	PSMC3	0.21	0.10	lasso	6	0.20	7.9e-06	5.5	-7.2	7.0e-13	-0.56	0.10	0.40	FALSE
27	GTEx	Skin Sun Exposed Lower leg	PSMC3	0.20	0.05	lasso	7	0.10	1.2e-08	6.3	-6.8	8.5e-12	-0.68	0.08	0.92	FALSE
2	GTEx	Adipose Subcutaneous	PTPRJ	0.05	0.05	lasso	2	0.04	3.9e-04	6.9	6.8	1.3e-11	0.59	0.01	0.97	FALSE
4	GTEx	Brain Cortex	MTCH2	0.21	0.19	lasso	6	0.16	4.0e-05	-6.3	-6.7	1.6e-11	-0.62	0.17	0.60	FALSE
35	METSIM	Adipose	RAPSN	0.11	0.01	enet	21	0.06	7.9e-09	3.5	6.7	1.7e-11	0.41	0.94	0.04	FALSE
42	ROSMAP	Brain Pre-frontal Cortex	PSMC3	0.15	0.08	bslmm	285	0.10	5.1e-13	5.5	-6.7	1.7e-11	-0.54	0.09	0.91	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MTCH2	0.03	0.00	bslmm	299	0.00	1.1e-01	5.7	-6.6	3.1e-11	-0.44	0.13	0.10	FALSE
17	GTEx	Nerve Tibial	SLC39A13	0.07	0.01	enet	14	0.02	7.6e-03	-4.8	-6.6	4.5e-11	-0.58	0.09	0.53	FALSE
63	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC39A13	0.06	0.01	blup	58	0.04	9.3e-04	5.1	-6.5	7.8e-11	-0.56	0.02	0.56	FALSE
32	METSIM	Adipose	C1QTNF4	0.24	0.31	lasso	7	0.31	1.2e-46	-6.2	6.3	2.5e-10	0.55	0.98	0.02	FALSE
45	YFS	Blood	PSMC3	0.02	0.01	blup	289	0.01	2.8e-05	-4.0	-6.3	2.7e-10	-0.48	0.19	0.72	FALSE
31	GTEx	Whole Blood	C1QTNF4	0.09	0.05	lasso	3	0.03	1.4e-03	-6.3	6.3	2.9e-10	0.54	0.27	0.58	FALSE
5	GTEx	Breast Mammary Tissue (Female)	PSMC3	0.02	0.01	lasso	1	0.04	2.5e-02	6.3	-6.3	3.0e-10	-0.72	0.02	0.24	FALSE
64	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMC3	0.02	0.02	blup	39	0.02	5.7e-03	-4.8	-6.3	3.6e-10	-0.69	0.02	0.38	FALSE
3	GTEx	Artery Aorta	PACSIN3	0.10	0.04	lasso	4	0.03	1.1e-02	3.5	6.3	3.9e-10	0.45	0.17	0.56	FALSE
14	GTEx	Muscle Skeletal	SLC39A13	0.05	0.01	lasso	3	0.01	8.5e-02	5.6	-6.2	5.3e-10	-0.59	0.06	0.47	FALSE
59	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTCH2	0.11	0.11	lasso	2	0.10	6.4e-12	-6.2	-6.2	6.7e-10	-0.53	0.00	1.00	FALSE
62	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1QTNF4	0.19	0.19	lasso	3	0.19	3.2e-09	-6.2	6.2	6.7e-10	0.53	0.00	1.00	FALSE
50	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1QTNF4	0.06	0.08	lasso	3	0.08	7.5e-09	-6.2	6.2	7.1e-10	0.52	0.00	1.00	FALSE
48	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUP160	0.03	0.01	blup	44	0.01	1.9e-03	-6.4	-6.1	1.3e-09	-0.63	0.01	0.73	FALSE
57	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1QTNF4	0.13	0.16	lasso	1	0.16	3.1e-09	-6.0	6.0	1.6e-09	0.51	0.00	1.00	FALSE
37	NTR	Blood	MTCH2	0.02	0.04	lasso	1	0.04	1.3e-11	-6.0	6.0	1.7e-09	0.51	0.97	0.03	FALSE
38	ROSMAP	Brain Pre-frontal Cortex	MTCH2	0.35	0.40	enet	9	0.40	4.7e-56	-6.2	-5.9	3.0e-09	-0.50	0.98	0.02	FALSE
16	GTEx	Nerve Tibial	PTPRJ	0.05	0.03	enet	13	0.03	2.7e-03	4.0	5.9	3.3e-09	0.51	0.13	0.40	FALSE
34	METSIM	Adipose	PSMC3	0.06	0.03	enet	28	0.04	2.3e-06	-5.3	-5.9	3.6e-09	-0.63	0.06	0.94	FALSE
61	The Cancer Genome Atlas	Brain Lower Grade Glioma	PSMC3	0.10	0.05	blup	39	0.08	3.7e-09	-4.8	-5.9	4.0e-09	-0.52	0.01	0.99	FALSE
60	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYBPC3	0.03	0.01	blup	43	0.02	3.2e-03	-4.8	5.8	5.5e-09	0.47	0.02	0.57	FALSE
28	GTEx	Skin Sun Exposed Lower leg	ARHGAP1	0.08	0.01	lasso	5	0.02	1.4e-02	5.1	-5.8	5.9e-09	-0.29	0.02	0.93	FALSE
25	GTEx	Skin Sun Exposed Lower leg	ACP2	0.16	0.14	enet	15	0.15	1.8e-12	4.9	-5.8	6.1e-09	-0.46	0.78	0.22	FALSE
49	The Cancer Genome Atlas	Colon Adenocarcinoma	KBTBD4	0.14	0.01	blup	13	0.02	1.6e-02	2.2	-5.8	6.8e-09	-0.56	0.00	0.50	FALSE
65	The Cancer Genome Atlas	Stomach Adenocarcinoma	C1QTNF4	0.06	0.04	lasso	4	0.03	4.3e-03	-6.1	5.8	7.3e-09	0.50	0.00	0.93	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	CKAP5	0.11	0.04	lasso	3	0.03	2.1e-02	5.7	5.8	7.8e-09	0.38	0.04	0.85	FALSE
30	GTEx	Testis	NR1H3	0.10	0.10	lasso	6	0.08	2.9e-04	6.1	-5.8	8.8e-09	-0.45	0.23	0.63	FALSE
53	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PSMC3	0.05	0.01	lasso	3	0.02	9.4e-04	4.0	-5.7	9.5e-09	-0.52	0.04	0.08	FALSE
6	GTEx	Cells Transformed fibroblasts	PSMC3	0.07	0.00	enet	13	0.02	2.3e-02	6.3	-5.7	1.0e-08	-0.59	0.04	0.72	FALSE
46	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1QTNF4	0.06	0.07	lasso	2	0.06	4.9e-06	-6.1	5.7	1.2e-08	0.48	0.00	1.00	FALSE
51	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FNBP4	0.10	0.03	blup	45	0.05	7.7e-06	-6.3	-5.7	1.4e-08	-0.53	0.00	0.99	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	PACSIN3	0.11	0.05	lasso	3	0.10	3.4e-06	4.1	5.6	1.8e-08	0.36	0.52	0.20	FALSE
13	GTEx	Muscle Skeletal	MTCH2	0.05	0.03	enet	15	0.04	1.5e-04	-6.4	-5.6	1.9e-08	-0.54	0.27	0.68	FALSE
22	GTEx	Skin Not Sun Exposed Suprapubic	DDB2	0.07	0.02	enet	13	0.04	3.5e-03	4.7	5.6	2.0e-08	0.40	0.13	0.15	FALSE
55	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1QTNF4	0.12	0.14	enet	4	0.16	6.5e-18	-6.2	5.6	2.1e-08	0.46	0.00	1.00	FALSE
11	GTEx	Lung	PSMC3	0.07	0.02	lasso	2	0.03	3.6e-03	5.6	-5.6	2.3e-08	-0.46	0.16	0.20	FALSE
8	GTEx	Esophagus Mucosa	ARFGAP2	0.05	0.06	lasso	4	0.05	4.4e-04	5.7	5.6	2.6e-08	0.31	0.24	0.29	FALSE
44	YFS	Blood	NUP160	0.02	0.01	blup	290	0.01	1.7e-04	-6.3	-5.5	4.2e-08	-0.63	0.57	0.08	FALSE
26	GTEx	Skin Sun Exposed Lower leg	PACSIN3	0.17	0.11	lasso	4	0.12	5.5e-10	4.1	5.5	4.8e-08	0.35	0.99	0.01	FALSE
56	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMC3	0.05	0.04	lasso	3	0.05	3.8e-06	-5.3	-5.4	5.2e-08	-0.57	0.67	0.22	FALSE
9	GTEx	Esophagus Mucosa	PACSIN3	0.24	0.19	lasso	8	0.21	7.5e-14	4.1	5.3	8.9e-08	0.38	1.00	0.00	FALSE
36	NTR	Blood	MADD	0.01	0.01	enet	8	0.01	4.7e-03	5.4	5.3	9.7e-08	0.31	0.16	0.08	FALSE
52	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NUP160	0.08	0.03	blup	42	0.04	6.7e-05	-6.5	-5.3	1.0e-07	-0.49	0.01	0.97	FALSE
10	GTEx	Esophagus Muscularis	C1QTNF4	0.10	0.05	enet	23	0.06	1.4e-04	-4.0	5.3	1.1e-07	0.42	0.68	0.20	FALSE
47	The Cancer Genome Atlas	Breast Invasive Carcinoma	C11orf49	0.05	0.00	blup	90	0.02	3.0e-04	2.9	5.3	1.2e-07	0.30	0.13	0.49	FALSE
12	GTEx	Lung	C1QTNF4	0.18	0.15	lasso	6	0.13	3.2e-10	-4.9	5.3	1.3e-07	0.47	0.58	0.42	FALSE
33	METSIM	Adipose	MYBPC3	0.11	0.10	enet	26	0.11	1.0e-15	-4.8	5.2	1.6e-07	0.44	0.30	0.70	FALSE
18	GTEx	Pancreas	LRP4	0.11	0.10	enet	16	0.14	1.8e-06	5.7	-5.2	1.8e-07	-0.34	0.16	0.83	FALSE
29	GTEx	Spleen	C1QTNF4	0.31	0.28	enet	29	0.34	1.8e-09	-6.3	5.2	1.8e-07	0.34	0.38	0.60	FALSE
39	ROSMAP	Brain Pre-frontal Cortex	ACP2	0.03	0.00	blup	295	0.02	1.5e-03	-4.8	-5.2	2.0e-07	-0.48	0.25	0.42	FALSE
40	ROSMAP	Brain Pre-frontal Cortex	C11orf49	0.02	0.02	blup	322	0.02	3.3e-04	5.4	5.2	2.4e-07	0.35	0.42	0.55	FALSE
19	GTEx	Pancreas	LRP4-AS1	0.10	0.08	lasso	6	0.12	1.4e-05	5.7	-5.2	2.5e-07	-0.31	0.21	0.73	FALSE
24	GTEx	Skin Sun Exposed Lower leg	DDB2	0.08	0.10	lasso	4	0.10	5.8e-09	6.0	5.1	2.9e-07	0.27	0.14	0.86	FALSE
58	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	NUP160	0.13	0.05	lasso	4	0.04	2.6e-03	5.1	-5.1	2.9e-07	-0.66	0.09	0.04	FALSE
15	GTEx	Muscle Skeletal	ARHGAP1	0.03	0.05	lasso	2	0.04	1.2e-04	5.1	-5.1	3.0e-07	-0.24	0.06	0.91	FALSE
54	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ACP2	0.03	0.03	blup	44	0.04	3.5e-05	6.1	-5.1	3.1e-07	-0.44	0.02	0.98	FALSE