Hub : Genes

FCRLB

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2400 0.0430 7.6e-12 0.077 0.126 0.187 0.189 0.178 1.1e-09 4.1e-15 2.7e-22 1.7e-22 4.2e-21
2 GTEx Adipose Subcutaneous 0.1630 0.0480 5.3e-04 0.007 NA 0.020 NA 0.028 7.7e-02 NA 8.1e-03 NA 2.2e-03
3 GTEx Brain Hippocampus 0.2628 0.1047 7.3e-03 0.061 NA 0.033 NA 0.064 1.6e-02 NA 5.8e-02 NA 1.3e-02
4 GTEx Cells Transformed fibroblasts 0.1950 0.0480 1.3e-07 0.028 NA 0.107 NA 0.098 3.4e-03 NA 2.3e-08 NA 8.2e-08
5 GTEx Skin Not Sun Exposed Suprapubic 0.0880 0.0360 4.3e-03 0.056 NA 0.058 NA 0.038 4.9e-04 NA 3.9e-04 NA 3.8e-03
6 METSIM Adipose 0.1134 0.0334 3.0e-06 0.028 0.048 0.043 0.049 0.042 3.7e-05 8.5e-08 4.9e-07 7.5e-08 5.0e-07
7 YFS Blood 0.1548 0.0277 0.0e+00 0.037 0.088 0.091 0.086 0.070 4.1e-12 2.5e-27 2.9e-28 1.0e-26 8.6e-22
8 TCGA Breast Invasive Carcinoma 0.0331 0.0143 4.6e-03 -0.001 0.010 0.001 NA -0.001 8.3e-01 2.6e-03 1.9e-01 NA 9.1e-01
9 TCGA Kidney Renal Papillary Cell Carcinoma 0.2110 0.0730 4.0e-04 -0.005 0.079 0.083 NA 0.008 8.9e-01 2.9e-05 1.8e-05 NA 1.1e-01
10 TCGA Brain Lower Grade Glioma 0.0894 0.0349 9.9e-05 0.000 0.030 0.025 NA 0.006 3.1e-01 2.0e-04 7.1e-04 NA 5.7e-02
11 TCGA Liver Hepatocellular Carcinoma 0.0880 0.0440 6.3e-03 0.033 0.042 0.033 NA 0.026 1.1e-02 4.5e-03 1.1e-02 NA 2.1e-02
12 TCGA Lung Squamous Cell Carcinoma 0.0620 0.0286 3.3e-03 0.015 0.018 0.015 NA 0.012 6.1e-03 3.5e-03 7.3e-03 NA 1.5e-02
13 TCGA Prostate Adenocarcinoma 0.0413 0.0216 5.1e-03 0.011 0.020 0.018 NA 0.024 2.2e-02 3.1e-03 5.3e-03 NA 1.2e-03
14 TCGA Soft Tissue Sarcoma 0.0690 0.0330 4.1e-03 0.020 0.024 0.009 NA 0.020 2.4e-02 1.3e-02 8.5e-02 NA 2.3e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 1.0 1.5 5.3 0.5 -1.1 1.2 0.8 -2.3 1.4 -0.3 -0.2 0.2 0.4 -2.3 0.0 1.1 2.0
Bipolar Disorder or Schizophrenia 0.5 1.1 3.1 0.1 -0.5 1.4 0.6 -1.5 1.8 -0.9 0.6 1.1 0.1 -1.5 0.8 1.4 0.7
Depressed Affect (Nagel 2018) 0.3 0.6 2.2 -1.2 1.5 -0.2 0.9 -0.1 0.8 -1.0 0.4 0.1 -0.7 -0.2 -0.3 1.0 0.7
Depression (Nagel 2018) 0.6 0.9 3.8 -1.5 1.2 -0.1 0.8 0.1 0.1 -0.2 -0.9 -1.9 -0.6 -0.8 -0.9 -0.0 1.3
Intelligence (Savage-Jansen 2018) 0.5 1.5 4.7 1.3 -1.5 1.3 0.9 -0.0 2.2 1.3 1.8 0.6 1.0 -0.7 -0.1 0.9 1.5
Neuroticism (Nagel 2018) 0.5 1.1 3.9 -0.3 0.9 1.1 1.7 -0.2 1.3 -1.6 1.2 0.2 -0.1 -0.8 0.2 2.0 0.8
Schizophrenia (2018) 0.3 0.5 1.4 -0.3 0.2 0.8 0.1 -0.0 1.2 -0.9 0.8 1.1 -0.2 -0.1 1.1 0.9 -0.7
Schizophrenia vs Biploar Disorder 1.0 1.3 6.2 0.2 0.9 0.6 0.4 1.0 0.4 -0.8 1.4 1.6 -0.0 1.3 2.5 0.5 -1.7
Worry (Nagel 2018) 0.2 0.3 2.7 0.1 0.3 0.2 0.6 -0.2 0.1 -1.6 0.6 0.3 -0.4 -0.3 0.5 0.4 -0.3
Alzheimer’s Disease (in mother) 0.9 1.0 3.1 -0.6 0.8 -1.2 -1.8 1.0 0.1 1.5 -1.1 -0.3 -1.0 0.9 0.5 0.3 -1.5
Alzheimer’s Disease (in father) 0.9 1.0 3.5 -0.2 1.0 0.8 1.9 -1.1 0.7 -1.6 0.3 0.6 -0.3 -1.6 0.4 -0.1 1.0
Alzheimer’s Disease (including proxy) 0.4 0.6 2.2 -0.9 1.5 -0.6 -0.6 0.1 0.5 0.2 -1.4 0.1 -1.0 -0.2 0.8 0.0 -0.7
Crohns Disease (2017) 1.0 2.2 8.3 2.3 -2.4 1.8 1.9 -0.8 -0.3 -1.1 0.6 -0.3 2.9 -1.0 0.0 1.1 1.0
Irritable Bowel Disease (IBD) 1.1 2.6 13.2 2.1 -2.8 1.3 1.5 0.1 -0.2 -0.3 -0.2 -1.5 3.6 -0.7 -0.2 0.4 2.1
Ulcerative Colitis (UC) 1.0 1.9 10.9 1.5 -1.9 0.3 0.4 0.9 -0.2 0.9 -0.2 -2.0 3.3 0.0 0.1 -0.1 2.1
Major Depression (MDD) 0.2 0.2 1.2 -0.5 0.3 -0.0 0.3 0.2 0.6 1.1 -0.3 0.6 -0.5 -0.1 0.6 -0.1 0.6
Reaction Time 0.4 0.8 3.7 -0.4 1.9 0.9 0.5 0.1 -0.0 -1.5 -0.0 -0.4 0.2 -0.7 0.5 1.8 0.2
Verbal and Numeric Reasoning (VNR) 0.5 1.1 4.2 1.2 -0.6 0.6 -0.5 0.6 2.0 1.3 1.8 1.5 0.9 0.4 0.7 0.5 0.3
Breast Cancer 0.2 0.5 2.4 0.0 -1.6 0.1 -0.6 -0.4 1.2 0.7 0.4 0.2 -0.1 -0.6 0.6 0.2 1.1
Ovarian Cancer 1.4 1.9 7.1 1.1 -0.4 2.2 1.0 0.2 0.8 -0.8 2.7 2.3 0.3 -0.7 1.5 1.8 -0.0
Prostate Cancer 0.6 0.8 2.8 0.6 -1.7 -0.9 -0.4 0.1 -0.7 1.4 -0.0 -0.2 0.5 1.1 -0.6 -1.6 -0.9
Age at First Birth 0.3 0.5 1.5 0.7 0.1 -0.1 -0.7 1.2 -0.2 -0.9 0.3 0.7 0.0 0.9 -0.2 0.6 -1.2
Bipolar Disorder (2011) 1.4 1.4 4.0 0.9 -2.0 1.4 1.2 -0.9 0.1 -1.4 0.6 1.1 0.7 -1.7 0.7 1.5 0.9
Body Mass Index (BMI) (2010) 0.3 0.4 1.4 0.4 -0.1 -0.3 -0.8 1.2 -0.9 0.1 -0.4 -0.3 0.3 0.6 -0.7 -0.7 -0.3
Coronary Artery Disease (CAD) 0.5 0.6 3.5 -0.6 0.9 -0.8 -0.7 0.7 -0.6 0.2 -0.5 0.7 -1.1 0.0 -0.2 -1.9 0.1
Crohns Disease (2012) 0.4 0.7 2.5 0.3 -1.6 0.3 1.3 -0.5 -0.8 -0.7 0.4 0.6 0.9 -0.6 -1.1 0.1 1.2
Mean Putamen Volume 1.3 1.5 6.1 0.3 1.6 0.1 0.6 2.5 -1.2 -0.6 2.0 0.3 1.3 0.8 0.8 1.8 -0.2
Fasting Glucose 2.5 3.0 10.0 -0.5 1.5 -2.1 -2.1 0.4 0.7 -1.9 -0.1 2.2 -1.9 2.7 0.2 -0.8 -3.2
HbA1C 1.3 1.5 6.4 0.9 -0.4 1.7 1.6 -0.7 0.6 -1.9 2.5 0.4 0.6 -0.5 0.5 1.4 0.5
HDL Cholesterol 0.3 0.5 1.8 -0.5 0.7 -1.2 0.1 -0.2 0.5 0.9 -0.4 -0.1 -0.9 0.5 -0.6 -1.3 -0.2
LDL Cholesterol 2.6 4.2 15.4 -1.9 1.4 -3.6 -1.4 2.1 0.4 -0.8 -0.3 0.8 -2.6 2.5 -1.3 -3.9 -1.5
Lupus 1.6 2.4 8.9 -1.4 1.2 2.0 1.0 -3.0 0.2 -1.2 -1.6 -0.8 -1.0 -2.5 -0.2 1.5 1.4
Neuroticism (2016) 1.1 1.6 5.1 0.8 0.0 1.6 2.2 -0.8 0.2 0.2 1.2 0.2 1.5 -1.4 1.2 2.2 1.4
Primary Biliary Cirrhosis 0.3 0.4 1.3 -0.0 0.1 0.1 0.2 1.1 0.7 -1.1 0.9 -0.7 0.1 0.3 0.6 -0.1 -0.5
Rheumatoid Arthritis 1.1 1.5 6.8 1.2 0.6 -0.3 -0.5 2.6 0.8 0.5 1.9 0.6 1.1 1.5 1.1 0.7 -1.5
Schizophrenia (2014) 0.1 0.3 0.8 0.2 -0.2 0.9 -0.4 -0.8 0.8 -0.3 0.5 0.7 0.1 -0.3 0.5 0.5 -0.6
Triglycerides 0.4 0.6 3.6 0.2 0.7 -1.0 -0.7 1.9 -0.9 0.0 0.3 0.4 0.3 1.1 -0.9 -0.5 -0.4
Type 2 Diabetes (T2D) (2012) 2.0 2.3 8.9 -1.5 3.0 -1.8 -1.0 1.7 1.8 -1.4 0.6 -0.5 -1.3 1.9 -1.3 0.3 -0.6
Ulcerative Colitis 0.9 1.2 4.6 1.2 -2.1 0.7 0.5 0.5 -0.9 0.1 0.3 -0.7 2.1 -0.7 1.1 0.1 1.7
Blood Eosinophil Count 0.1 0.6 2.2 -0.5 0.5 -0.6 0.1 1.5 0.5 0.4 0.5 0.5 -0.3 1.4 -1.1 -0.9 -0.5
Blood Platelet Count 0.7 8.5 18.1 1.1 -0.6 4.0 4.3 -4.0 -0.5 -4.1 -0.3 -2.1 3.5 -3.4 -1.9 1.2 4.2
Blood Red Count 0.7 7.0 19.3 -2.3 0.5 -4.4 -3.2 4.0 2.0 1.1 1.1 1.9 -3.0 3.2 -1.9 -2.9 -2.2
Blood White Count 1.9 14.1 52.0 6.8 -4.4 6.2 3.3 -1.7 -1.7 0.7 3.1 -0.2 7.2 -0.7 -0.8 2.6 2.2
Heel T-Score 0.2 1.3 5.3 -0.8 -1.1 -1.7 -1.2 -0.9 -0.8 1.3 -1.0 0.9 -0.5 0.9 0.2 -2.3 -1.1
BMI 0.1 0.5 3.8 -0.3 0.3 0.6 0.2 0.1 1.0 -0.1 0.2 -0.3 0.3 -0.4 -1.9 -0.4 1.3
Height 0.1 1.5 3.6 1.4 -1.9 -0.1 -1.9 -0.3 -1.1 1.1 -0.6 -1.3 1.0 1.5 0.0 1.0 -1.6
Waist Hip Ratio (WHR) 0.2 1.1 3.5 1.9 0.3 1.1 -1.1 1.1 -1.1 0.4 1.2 -0.1 1.4 0.0 -0.4 1.6 -0.7
Systolic Blood Pressure 0.2 0.9 2.3 0.7 -1.5 1.2 1.0 0.5 -1.3 -0.9 0.2 0.7 0.6 -1.1 0.3 1.5 0.7
Smoking Status 0.6 1.5 7.3 0.4 -0.9 1.0 1.0 -1.0 -1.0 0.2 -1.4 -2.7 1.1 -1.4 -0.7 0.3 1.7
Allergy or Eczema 1.1 2.8 10.4 -2.3 1.8 -1.7 0.2 0.2 2.9 -1.1 0.1 1.8 -3.2 1.4 -0.8 -0.7 -1.5
Cardiovascular Disease 0.5 1.6 4.0 -1.1 1.8 -1.1 -0.8 0.8 -0.0 -1.2 0.4 2.0 -1.9 0.5 1.6 -0.1 -1.9
Hypothyroidism (self reported) 1.4 3.1 8.6 0.8 0.4 2.9 2.6 -2.4 1.7 -0.6 0.0 -1.4 1.9 -1.7 -1.1 1.3 2.7
Respiratory disease 0.6 1.4 4.0 -2.0 1.8 -1.1 0.3 1.1 1.5 -0.6 -1.2 0.3 -1.2 1.0 -1.7 -0.4 0.0
Type 2 Diabetes (T2D) (2018) 0.5 0.9 4.2 -1.7 2.0 0.3 0.3 -0.4 1.4 0.5 0.4 -0.2 -0.5 -0.4 -0.5 1.0 1.3
Lung FEV1/FVC ratio 1.1 5.6 10.6 2.7 -2.0 3.2 3.0 -1.6 -0.8 -0.3 2.4 1.1 2.5 -3.2 1.9 3.3 2.7
Lung FVC 0.8 4.0 12.4 0.2 -1.1 -2.1 -2.5 0.5 -2.2 1.7 -3.1 -0.7 -1.9 0.8 1.1 -3.5 -2.7
Neuroticism 0.3 0.6 4.0 -0.2 0.0 0.2 0.9 -0.7 0.7 -2.0 0.6 0.8 -0.7 -0.6 0.5 0.9 -0.1
Chronotype (morning person) 1.0 2.4 6.1 -1.7 1.6 -2.0 -0.7 -0.3 1.4 -2.5 -0.8 0.9 -2.4 0.6 -2.0 -2.0 -0.1
Hair Pigment 0.0 0.8 2.6 0.7 0.6 1.0 0.6 1.5 0.0 -1.6 -0.1 -1.2 1.1 -0.2 0.7 0.8 0.4
Tanning 0.2 2.6 5.9 -0.2 0.2 -1.8 -2.4 1.6 -0.9 2.4 0.6 0.8 -0.7 2.3 0.4 -2.4 -2.4
Hand grip strength (left) 0.3 0.8 7.0 -0.4 -0.4 0.5 0.4 -1.1 0.1 -0.9 -0.1 -0.6 0.0 0.1 -2.6 0.5 1.0
Number of treatments/medications taken 1.2 2.2 6.6 0.3 1.0 2.5 1.9 -0.7 1.3 -1.4 1.1 0.1 0.1 -1.6 2.4 2.6 -0.1
Average weekly spirits intake 0.2 0.3 0.9 0.5 -0.9 0.4 -0.1 0.5 0.2 1.0 0.8 -0.2 0.7 -0.1 -0.0 0.4 0.6
Sensitivity / hurt feelings 0.2 0.3 1.6 -0.6 -0.0 -0.6 -0.2 0.8 0.2 1.3 0.3 0.3 0.1 0.5 -0.4 -0.0 0.6
Frequency of depressed mood in last 2 weeks 1.0 1.4 7.1 -0.8 0.6 0.7 0.8 -0.6 -0.1 0.3 -1.1 -2.7 0.6 -0.7 -2.2 0.2 1.8
Hearing difficulty/problems: Yes 0.2 0.4 1.3 0.6 -0.9 0.4 0.7 0.8 -0.8 0.2 -0.2 -0.4 1.1 0.4 -0.0 -0.4 0.2
Relative age of first facial hair 0.2 0.4 1.4 -0.4 0.4 -0.7 0.4 -0.3 0.2 1.2 0.5 -0.7 0.7 0.2 -0.9 -0.4 0.8
Other serious medical condition/disability diagnosed by doctor 0.5 0.6 2.7 0.7 0.7 1.6 0.7 -0.5 0.2 -1.1 0.8 -0.4 0.8 -0.6 0.6 0.9 0.1
Ever used hormone-replacement therapy (HRT) 0.6 0.7 2.3 -0.3 0.3 0.4 1.2 -0.6 1.0 -0.2 0.2 0.9 0.4 -1.0 1.4 0.9 1.5
Ever had hysterectomy (womb removed) 0.6 0.6 2.2 -0.7 -0.4 0.0 -0.5 -1.5 0.5 0.5 -1.3 -0.6 -0.2 -1.1 -1.1 0.0 0.9
Systolic blood pressure, automated reading 0.9 2.6 10.4 0.9 -0.8 2.5 2.3 -0.5 0.0 -1.9 0.7 0.5 1.1 -2.0 -0.0 3.2 1.9
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 3.1 -1.2 0.6 -0.9 -0.4 -0.3 0.0 0.5 -1.7 -1.8 0.0 0.7 -0.5 -1.6 -0.3
Angina 0.5 0.7 2.2 -0.3 -0.3 0.5 0.8 -0.1 -0.7 -1.5 0.2 1.0 -0.8 -0.2 1.4 0.6 -1.3
Medication for hormone replacement therapy 0.5 0.6 2.1 -0.4 0.7 -0.1 0.8 -0.8 1.5 1.1 0.6 0.1 -0.3 -0.3 1.2 0.9 0.7
Vitamin and mineral supplements 1.1 1.5 3.7 -1.9 1.7 -1.3 -1.4 1.8 -0.4 1.6 -0.6 0.2 -1.2 1.0 -0.8 -1.3 -0.5
Supplements: Zinc 0.5 0.6 3.6 -0.4 0.9 0.1 0.5 -0.5 1.9 -0.2 0.5 -0.9 0.5 0.5 0.0 1.1 0.4
Medication: Co-codamol 1.6 1.9 6.3 -1.2 1.4 0.8 0.1 0.0 2.3 -1.5 0.7 2.5 -1.0 0.9 -1.1 2.1 -0.3
Medication: Metformin 0.6 0.8 2.7 -0.5 1.0 1.3 0.8 -1.4 0.2 -0.2 -0.5 -0.4 0.0 -1.6 -0.3 1.3 1.1
Diabetes (father) 0.9 1.2 3.9 -1.3 -0.2 0.3 0.7 -1.3 -0.1 0.9 -2.0 -1.8 0.0 -1.6 0.3 -0.1 1.4
Diabetes (mother) 0.5 0.7 3.8 0.9 -0.1 0.1 0.1 0.4 -1.9 0.2 0.3 0.0 1.2 -1.0 0.8 0.2 1.1
Severe depression (siblings) 1.3 1.5 4.1 1.9 -1.3 2.0 0.2 -1.0 0.8 -1.9 1.0 0.4 0.3 -0.8 1.9 -0.1 -1.0
Pack years adult smoking proportion 0.9 1.4 6.7 -1.0 0.5 -0.3 0.5 -0.7 -1.3 -2.6 -1.9 1.4 -1.6 -0.4 0.0 -0.0 -0.8
Impedance of leg (right) 0.2 1.0 5.5 1.2 -1.6 0.9 -0.2 -0.1 -2.3 -0.2 -0.7 -0.8 1.1 -0.1 0.5 0.7 -0.8
Leg fat-free mass (left) 0.0 0.2 0.6 -0.2 0.5 -0.1 -0.8 -0.0 0.6 0.2 0.5 -0.2 -0.2 0.2 -0.5 0.5 0.3
Trunk fat percentage 0.4 1.6 4.8 0.8 -0.4 2.2 1.3 -1.6 1.4 -0.8 0.0 -1.6 1.3 -1.5 0.4 1.2 1.0
Hand grip strength (right) 0.2 0.6 2.7 0.2 -0.4 -0.1 -1.1 -0.2 -1.6 -0.3 -0.7 -0.1 0.1 0.5 -1.6 0.3 -0.2
Townsend deprivation index at recruitment 1.2 1.6 8.7 -1.3 1.5 -0.0 -0.2 -0.0 1.2 -0.7 -0.9 -3.0 -0.4 1.2 -2.4 -0.2 -0.1
Current tobacco smoking 0.5 0.8 3.0 -0.4 0.6 -0.8 -0.3 0.2 -1.4 -0.1 -1.7 -1.1 -0.3 0.8 -1.3 -0.9 -0.2
Average weekly fortified wine intake 1.2 1.4 4.3 0.9 -0.8 1.6 1.5 -0.5 -1.4 -0.5 -0.0 -0.9 1.3 -2.1 0.3 1.3 1.5
Maternal smoking around birth 0.8 1.2 4.0 1.0 0.4 1.5 2.0 0.1 1.5 -1.2 1.6 -0.6 1.0 -0.2 0.4 0.6 0.7
Fed-up feelings 0.7 1.3 4.7 -2.2 1.1 -1.1 -1.1 0.5 -0.2 -0.0 -1.6 -0.8 -1.1 0.5 -2.1 0.1 0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 2.6 -0.2 0.6 0.5 1.2 0.2 -1.6 0.3 -0.7 -1.1 1.0 -0.4 -1.0 0.5 1.1
Relative age voice broke 0.2 0.3 1.6 -0.4 0.3 -0.2 -0.0 -0.4 0.7 0.5 0.5 -0.4 0.3 -0.3 -0.4 0.1 1.3
Taking other prescription medications 0.8 1.2 5.1 0.7 0.1 2.3 1.5 -0.7 0.4 -1.3 0.4 -0.4 0.7 -1.3 0.8 1.9 0.2
Age when periods started (menarche) 0.3 0.7 2.7 -0.3 1.6 -0.2 0.5 0.4 -0.4 -1.4 0.3 -0.0 -0.1 1.4 -0.6 -0.2 -1.5
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 4.1 -1.0 0.5 -0.3 0.7 -2.0 2.0 1.1 -1.6 -0.8 -0.5 -1.3 -0.3 -0.2 1.7
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 3.2 0.4 -0.3 -0.6 -1.8 0.7 0.5 1.1 1.1 -0.7 -0.1 1.1 0.7 -1.0 -1.2
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 2.2 1.2 -0.1 0.4 0.5 0.0 -0.3 0.3 0.7 0.1 1.5 -0.2 1.3 0.0 0.5
Qualifications: CSEs or equivalent 0.6 0.9 3.1 -0.9 1.7 0.1 0.6 -1.1 0.7 -1.4 -0.7 -1.4 -1.1 -0.5 -0.1 -0.2 0.6
Serious illness, injury or assault to yourself 1.2 1.4 7.9 -1.7 0.8 -1.4 -0.2 0.2 0.4 -0.7 -0.2 0.6 -2.8 -0.7 1.6 -0.8 -1.5
High blood pressure 0.3 0.7 2.1 -0.5 1.4 -0.2 -1.0 1.5 -1.1 0.0 0.3 0.2 -0.2 0.6 0.2 1.3 -1.1
Hayfever, allergic rhinitis or eczema 0.9 1.9 5.6 -1.8 1.7 -1.1 0.7 -0.4 2.3 -1.1 0.1 1.7 -2.4 0.8 -1.2 -0.8 -0.8
Multivitamins +/- minerals 0.6 0.7 3.4 1.9 -1.1 0.1 -0.7 -0.5 0.9 0.7 1.0 0.1 0.3 0.4 0.3 0.4 -1.2
Stomach or abdominal pain in last month 0.9 1.2 3.7 -1.2 1.3 -0.6 1.2 -1.0 -0.6 0.9 -1.5 -0.9 -0.6 -0.7 -0.7 -1.9 1.0
Supplements: Glucosamine 0.9 1.2 3.3 1.2 -0.7 1.2 1.8 -1.8 0.0 -0.2 -0.6 -0.6 1.2 -1.4 1.4 0.3 0.5
Diverticular disease/diverticulitis (self-reported) 0.9 1.1 4.2 -1.5 2.0 -0.4 0.1 0.4 1.9 1.4 0.1 -0.4 -1.5 0.4 -0.3 -0.1 0.1
Medication: Atenolol 0.5 0.6 2.5 0.3 -0.6 0.9 0.8 1.0 -0.0 -0.2 0.8 -0.1 0.4 -0.4 1.6 1.2 0.3
Medication: Levothyroxine sodium 1.3 2.3 7.3 0.3 -0.1 2.7 1.7 -1.3 0.9 0.8 -0.4 -1.9 1.9 -1.3 -0.8 1.3 2.7
Sitting height 0.1 0.7 2.9 0.4 -0.6 -0.7 -1.7 0.7 -0.7 -0.1 0.6 0.6 -0.2 1.2 0.3 0.3 -1.4
Chronic bronchitis/emphysema (father) 0.5 0.6 2.4 -0.1 1.5 0.1 -0.1 1.0 0.3 -1.4 -0.3 -0.3 0.9 0.8 0.5 0.6 -0.9
High blood pressure (mother) 0.2 0.3 1.2 -0.4 0.9 0.1 -0.5 0.2 -0.4 0.5 0.0 0.9 -1.1 -0.6 0.5 -0.1 -0.6
Body mass index (BMI) 0.3 1.3 5.2 -0.4 1.0 1.4 1.4 -0.9 2.3 -0.9 0.9 -0.6 0.2 -1.2 -0.6 0.9 1.7
Impedance of leg (left) 0.2 1.2 6.2 1.4 -1.7 0.5 -0.3 0.1 -2.5 -0.1 -1.0 -0.9 1.1 -0.2 0.9 0.4 -1.1
Leg predicted mass (left) 0.0 0.2 0.6 -0.1 0.5 0.0 -0.8 -0.1 0.6 0.2 0.6 -0.2 -0.2 0.1 -0.6 0.5 0.3
Trunk fat mass 0.3 1.3 4.4 1.0 -0.4 2.1 1.0 -1.3 1.2 -0.5 0.4 -1.4 1.4 -1.2 0.3 1.4 1.0
Waist circumference 0.1 0.4 1.2 -0.1 1.1 1.0 -0.0 -0.4 0.6 -0.4 0.3 -0.5 0.1 -0.6 -0.9 1.1 0.7
Number of incorrect matches in round 0.3 0.5 2.6 0.9 -0.2 0.3 0.4 -0.2 -0.9 -0.4 -0.2 -0.1 0.3 -0.7 1.6 -1.1 -0.6
Past tobacco smoking 0.3 0.5 1.1 0.5 -0.3 -0.7 -0.8 1.0 0.1 1.0 1.0 0.9 -0.0 1.0 0.1 -0.5 -0.6
Alcohol usually taken with meals 0.5 0.8 3.9 0.6 0.7 0.3 0.4 0.4 1.1 0.1 1.5 2.0 0.3 0.5 1.2 0.4 0.1
Nervous feelings 0.4 0.8 5.1 -0.3 0.3 1.3 0.4 -0.1 1.6 -0.2 0.8 0.2 0.2 -0.2 -0.0 2.3 0.8
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 2.8 -0.8 0.7 1.0 1.1 0.3 -0.9 -0.1 -0.6 -1.7 0.8 -0.5 -0.9 1.4 1.3
Hearing difficulty/problems with background noise 0.2 0.4 1.1 0.1 -0.6 0.3 1.1 0.2 -1.0 0.1 -0.6 -1.0 0.8 -0.4 0.4 0.2 0.2
Hair/balding pattern: Pattern 2 0.4 0.5 2.2 -0.7 0.4 0.4 1.0 -0.1 0.6 -0.9 0.3 0.4 -0.6 -0.9 1.5 -0.1 0.6
Had menopause 0.4 0.5 1.9 -0.2 0.3 -1.4 -1.0 0.7 0.5 0.8 0.1 0.6 -0.2 1.2 0.4 -0.4 -1.0
Had other major operations 0.8 1.0 3.6 0.3 0.0 1.9 0.6 -0.7 -0.9 -0.8 -0.7 -0.4 0.4 -1.5 1.3 1.8 0.4
Forced vital capacity (FVC) 0.8 3.1 10.8 -1.2 -1.0 -1.7 -3.3 0.6 -0.7 0.9 -2.4 -0.6 -2.2 1.9 -0.8 -2.4 -2.2
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.9 6.2 -0.6 0.2 -2.0 -2.5 1.1 0.4 1.1 0.3 -0.2 -0.9 1.9 0.6 -2.2 -1.9
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 2.6 1.1 -0.7 1.4 0.9 -0.4 0.9 -0.5 0.2 -1.1 1.6 -0.8 0.8 1.0 0.8
Qualifications: None of the above 0.4 1.0 4.2 0.3 1.2 1.1 0.9 0.3 1.2 0.0 1.7 0.3 0.7 0.6 -0.3 2.0 0.4
Financial difficulties in last 2 years 1.3 1.7 5.3 -1.2 1.2 0.7 0.1 -1.6 1.0 -1.9 -2.3 -0.8 -2.1 -0.9 -0.9 -1.0 -0.3
Mouth/teeth dental problems 1.6 2.4 8.5 0.2 -0.2 -2.2 -2.9 1.5 -0.2 2.2 -0.1 0.4 -0.6 2.2 -0.4 -2.1 -2.0
Heart attack 0.7 0.9 3.2 -0.5 0.4 0.3 0.0 0.8 -0.6 0.2 -0.3 1.5 -1.1 0.3 1.8 1.0 -1.5
Allergy 1.1 2.5 6.1 1.9 -2.4 1.6 0.4 -1.0 -2.3 1.2 -0.3 -1.8 2.5 -1.5 1.0 0.5 1.5
Pain all over the body in last month 0.6 0.7 1.8 0.6 0.4 1.4 0.7 -0.9 -1.0 -1.0 0.1 -0.7 0.1 -1.0 1.0 1.1 -0.4
Diabetes (self-reported) 0.1 0.2 0.8 -0.9 0.7 -0.5 -0.0 -0.1 -0.1 0.4 -0.5 -0.5 -0.3 0.1 0.4 -0.8 -0.0
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 2.5 0.5 -0.5 0.5 1.4 -1.3 1.6 -0.9 1.5 1.3 -0.5 -0.0 -0.5 -0.2 -0.3
Medication: Ramipril 0.4 0.6 3.5 -0.6 0.7 0.8 0.5 0.6 -0.3 -0.1 0.8 0.9 -0.3 -0.6 0.3 1.9 0.4
Medication: Simvastatin 1.6 2.4 7.1 -1.5 1.8 -1.2 -0.7 1.7 0.9 0.3 1.9 2.7 -1.6 1.9 0.3 -0.1 -2.2
Fluid intelligence score 0.6 1.3 4.0 1.1 -1.8 0.5 0.0 -0.1 1.9 2.0 1.5 1.2 0.9 0.2 1.1 -0.0 0.3
Illnesses of siblings 0.5 0.7 2.4 -0.9 -1.2 -1.3 0.0 -0.3 -1.0 0.4 -0.6 -0.4 -0.4 -0.3 -1.6 -1.2 0.9
Neuroticism score 0.2 0.4 2.2 0.0 0.4 0.6 1.5 -0.1 -0.2 -1.0 0.3 -0.2 0.7 -0.3 -0.2 0.8 0.8
Weight 0.1 0.4 1.5 0.1 0.4 1.0 0.1 -0.5 1.2 -0.3 0.7 -0.6 0.4 -0.4 -0.5 1.1 0.7
Impedance of arm (right) 0.1 0.7 3.8 0.5 -0.2 0.7 -0.7 0.3 -0.5 -0.2 -0.0 0.2 0.1 0.9 1.5 1.1 -2.0
Arm fat percentage (right) 0.5 2.0 5.6 0.3 0.7 2.4 1.8 -1.6 2.4 -1.5 0.8 -0.9 0.7 -1.6 0.5 1.4 1.2
Trunk fat-free mass 0.1 0.4 2.0 0.3 0.0 -0.5 -1.4 0.7 0.0 0.8 0.7 0.3 -0.2 0.7 -0.5 0.3 -0.1
Hip circumference 0.1 0.5 2.0 -1.1 0.4 0.8 0.4 -0.8 1.0 -0.5 -0.4 -0.9 -0.1 -0.6 -0.4 0.4 1.4
Time employed in main current job 0.4 0.5 1.9 0.9 -0.3 -0.1 -1.4 0.3 -0.2 0.7 0.7 -0.5 0.6 0.8 0.5 0.4 -0.8
Alcohol intake versus 10 years previously 0.8 1.2 3.8 -1.8 1.9 -1.1 -0.2 -0.1 0.4 -0.9 -0.7 1.3 -2.0 -0.2 -1.0 -0.6 -0.1
Father’s age at death 0.9 1.3 7.7 1.3 -1.6 0.5 -0.2 0.1 -0.2 2.8 -0.5 -1.1 1.8 -0.6 -0.1 -0.3 0.6
Worrier / anxious feelings 0.3 0.5 2.3 0.3 0.4 -0.1 1.1 -0.2 -0.5 -0.5 0.3 1.5 -0.3 -0.3 0.9 1.1 -0.2
Frequency of tiredness / lethargy in last 2 weeks 1.2 1.9 7.8 -1.1 1.6 1.2 1.3 -0.4 -1.0 0.2 -2.0 -2.8 0.3 -1.5 -0.3 1.1 1.6
Falls in the last year 2.1 2.9 9.0 0.8 -0.1 2.2 3.0 -3.0 0.5 -1.5 -1.5 -1.4 0.8 -2.7 0.2 0.5 1.5
Hair/balding pattern: Pattern 3 0.4 0.6 3.8 -1.3 0.2 -0.7 -0.3 0.5 0.4 0.6 0.1 1.9 -1.1 0.3 -0.4 0.3 -0.2
Number of live births 0.2 0.3 1.5 0.0 1.0 -0.1 -0.6 1.2 0.1 -0.0 0.3 0.4 0.2 0.9 -0.0 -0.0 -0.1
Forced expiratory volume in 1-second (FEV1) 0.4 1.3 5.7 -0.1 -2.2 -0.8 -2.4 0.3 -1.0 1.3 -1.2 -0.7 -0.8 0.8 0.3 -1.0 -1.0
Pulse rate 0.3 0.4 2.8 0.3 -0.2 0.0 -0.4 0.9 -0.5 0.8 1.7 0.1 0.7 0.7 -0.4 0.2 0.4
Happiness 1.1 1.3 6.6 0.4 -0.5 -0.7 -1.4 0.9 -2.6 1.7 -1.4 -0.4 0.9 1.1 -1.1 -0.7 -0.3
Noisy workplace 1.8 2.2 6.6 -2.5 1.9 -2.2 -0.8 0.7 0.2 -0.3 -1.1 -0.5 -2.6 1.3 -0.2 -1.9 -1.1
Qualifications: A levels/AS levels or equivalent 0.5 1.1 7.7 1.5 -2.8 0.6 -0.6 -0.8 0.3 1.7 0.1 0.1 0.3 -1.1 0.2 0.6 0.3
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 2.1 0.0 0.0 -0.2 -0.9 0.9 -0.8 0.2 0.3 0.9 -0.4 -0.1 1.4 1.4 -0.9
Mouth/teeth dental problems: Dentures 1.2 2.0 6.0 -1.7 1.2 0.8 2.5 -1.6 1.6 -2.2 0.0 0.7 -0.8 -0.9 -0.8 1.2 1.6
Asthma 0.5 1.0 3.1 -1.3 1.8 -0.9 -0.4 1.4 1.5 -0.7 -0.2 1.0 -1.1 0.9 -1.1 -0.2 -0.3
Medication: Ibuprofen (e.g. Nurofen) 3.1 3.9 12.9 3.1 -0.8 3.6 1.8 0.1 -0.2 -0.5 2.0 -0.6 2.6 -1.9 3.2 1.4 0.9
Medication: Cholesterol lowering 0.9 1.3 2.7 -1.5 1.6 -0.1 0.6 0.9 -0.1 -1.6 0.3 1.6 -1.6 0.2 1.4 0.7 -1.5
Depression (self-reported) 0.5 0.6 2.2 -0.4 1.5 -0.3 -0.5 0.8 -0.5 -1.2 0.3 -0.1 -0.6 0.7 -0.9 0.2 -0.9
Medication: Lansoprazole 0.6 0.7 2.1 -1.1 0.9 -0.5 0.1 -0.8 -0.7 0.3 -1.2 -1.4 -0.8 -0.9 -0.7 -0.2 0.7
Prospective memory result 0.6 0.8 2.4 -0.3 0.4 -0.6 -1.3 1.5 -0.1 0.8 1.2 0.7 -0.2 1.2 -1.1 0.6 -0.2
Lung cancer (father) 0.2 0.2 1.5 -0.2 -0.0 0.4 0.6 -0.5 -0.2 -1.2 0.3 0.2 0.1 0.1 -0.3 0.0 0.7
Illnesses of mother 0.7 0.8 3.0 0.1 -1.0 1.0 0.6 -0.9 0.9 -1.2 0.2 -0.7 0.4 0.2 -1.7 1.2 0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.4 7.4 0.5 -2.7 0.0 -1.9 -0.1 -1.6 1.2 -1.3 -1.6 0.0 0.1 0.2 -0.6 -0.4
Pulse wave Arterial Stiffness index 0.7 0.8 2.7 -1.6 -0.1 -0.9 -0.1 -0.1 -0.9 -0.5 -1.7 -0.4 -0.9 -0.5 -0.7 -1.0 0.6
Impedance of arm (left) 0.1 0.5 2.9 0.6 -0.4 0.6 -0.4 0.0 -0.5 -0.3 -0.1 0.3 0.2 0.7 1.3 1.1 -1.7
Arm fat mass (right) 0.4 1.5 4.5 0.4 0.4 2.1 1.3 -1.2 1.9 -0.6 0.9 -0.9 0.9 -1.3 0.2 1.6 1.4
Trunk predicted mass 0.1 0.4 2.0 0.4 0.0 -0.4 -1.4 0.7 -0.0 0.8 0.7 0.3 -0.2 0.7 -0.5 0.3 -0.1
Standing height 0.1 1.4 5.2 1.1 -1.4 -0.2 -2.3 0.6 -1.9 1.2 -0.1 -0.1 0.6 1.4 0.1 1.1 -1.6
Length of working week for main job 0.4 0.4 3.1 0.5 -0.8 0.6 0.1 0.3 0.9 -0.1 0.4 -0.4 0.2 -0.1 0.4 1.8 -0.2
Exposure to tobacco smoke at home 0.4 0.4 1.6 -0.2 1.3 -0.2 -0.5 -0.2 0.1 -0.5 -0.8 -1.1 0.3 0.3 0.7 -0.1 -1.0
Breastfed as a baby 0.6 0.8 2.6 -1.4 0.5 -0.2 -0.4 1.2 1.1 0.2 0.5 0.0 -1.1 -0.4 -1.6 0.1 1.2
Tense / ‘highly strung’ 1.0 1.7 5.6 0.7 -0.4 2.4 2.3 -0.9 -1.2 -0.5 -0.8 -0.5 1.5 -1.9 0.1 1.1 1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 0.9 3.5 1.9 -0.9 1.3 0.4 -0.2 -0.5 -0.7 0.0 -1.1 0.8 -0.3 1.7 0.7 -1.0
Hair/balding pattern: Pattern 4 0.2 0.4 2.1 -0.2 -0.2 -0.6 -0.2 0.9 -0.7 1.4 -0.7 0.0 0.0 0.2 -0.8 -0.3 0.3
Birth weight of first child 0.6 1.0 3.8 0.8 0.1 0.6 0.3 0.6 -1.9 1.1 0.2 0.1 1.8 -0.6 0.3 1.4 1.5
Peak expiratory flow (PEF) 0.4 0.9 3.0 0.6 -1.5 -0.3 -1.4 1.4 -0.2 1.7 0.7 -0.1 0.8 1.2 0.5 0.4 -0.4
Pulse wave reflection index 1.3 1.6 8.4 -1.8 -0.4 -0.4 -0.1 -1.7 0.4 -1.4 -2.9 -0.5 -1.4 -1.5 -0.5 -0.5 0.9
Ever highly irritable/argumentative for 2 days 1.1 1.3 3.0 0.8 -0.6 1.5 1.7 -1.2 -0.3 -0.5 -0.8 -1.6 1.6 -1.4 -0.4 -0.3 1.7
Loud music exposure frequency 1.4 1.5 5.1 0.4 -1.2 0.8 1.3 -2.1 -0.7 -1.2 -2.2 -1.1 0.2 -1.8 -0.5 -1.0 0.8
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 2.3 -0.6 -0.4 0.3 -0.8 -0.5 -0.8 1.3 -0.8 -0.8 0.2 -0.4 -1.5 -0.2 1.3
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 3.5 0.2 -0.5 1.0 1.4 -0.4 -0.6 -1.0 -0.4 -0.9 0.2 -1.9 1.6 -0.0 0.5
Blood clot in the leg (DVT) 0.5 0.6 5.4 0.3 0.3 0.3 -0.3 -0.1 2.3 -0.8 1.0 0.4 -0.2 0.1 0.4 0.8 -0.1
Medication: Paracetamol 0.9 1.5 5.2 -0.5 1.9 0.7 1.3 -1.8 0.0 -2.3 -1.2 -1.5 -0.8 -1.2 -0.4 -0.5 0.1
Headache pain in last month 0.6 1.0 3.9 0.4 1.0 2.0 1.1 -0.3 0.3 -0.2 -0.2 -0.7 0.6 -1.3 -0.6 1.6 1.2
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 4.3 1.9 -1.6 0.5 0.3 -1.3 1.2 1.1 0.5 -1.0 2.1 -0.4 -1.3 -0.6 2.0
Glaucoma (self-reported) 1.4 1.7 5.7 -0.9 0.3 1.6 1.6 -2.4 0.2 -1.2 -1.2 -0.1 -0.4 -2.1 -0.0 1.2 1.5
Gout (self-reported) 0.4 0.6 4.6 0.1 0.5 0.1 1.1 -0.2 -0.2 -0.3 0.7 2.1 -0.2 0.4 0.9 0.3 -0.6
Hypothyroidism/myxoedema (self-reported) 1.4 2.7 8.1 0.3 0.1 2.8 2.3 -2.1 1.2 0.0 -0.7 -1.3 1.6 -1.9 -0.8 1.3 2.9
Medication: Amlodipine 0.2 0.3 1.6 0.5 0.3 0.8 0.3 -0.1 -0.3 0.4 0.3 0.0 0.1 -0.8 1.3 0.1 -0.1
Medication: Ventolin 100micrograms inhaler 2.8 3.6 10.0 0.1 1.3 2.5 3.2 -0.4 2.9 -1.9 1.7 0.8 1.1 -1.2 -1.1 2.8 2.3
Birth weight 2.4 5.2 14.4 2.5 -2.0 3.8 2.3 -1.8 -2.1 -0.5 -0.6 -2.2 3.4 -2.2 -0.1 2.6 2.5
Chronic bronchitis/emphysema (mother) 0.2 0.2 0.9 0.1 -0.4 -0.1 0.0 0.6 -0.2 0.3 0.3 -1.0 -0.2 -0.1 -0.4 -0.9 0.1
High blood pressure (siblings) 0.8 1.2 4.2 0.6 1.3 1.7 0.8 -0.7 2.0 -1.1 0.7 0.7 0.1 -0.1 1.3 1.4 -0.8
Forced vital capacity (FVC), Best measure 0.6 2.1 9.0 -0.3 -1.9 -0.8 -3.0 0.3 -1.5 0.7 -2.1 -1.5 -1.0 1.1 -0.5 -1.4 -1.6
Body fat percentage 0.4 1.8 5.0 0.6 -0.1 2.2 1.6 -1.8 1.5 -1.2 0.1 -1.6 1.2 -1.7 0.1 1.3 1.3
Leg fat percentage (right) 0.5 1.9 6.0 0.5 0.1 2.4 1.7 -1.5 1.3 -1.2 0.4 -1.7 1.3 -1.7 -0.4 1.6 1.6
Arm fat-free mass (right) 0.0 0.2 1.1 0.3 -0.4 -0.3 -1.0 -0.1 0.0 0.7 0.1 -0.3 0.1 -0.1 -1.0 -0.1 0.6
Exposure to tobacco smoke outside home 0.2 0.3 1.0 -0.7 -0.4 -0.3 -0.7 -0.2 -0.2 -0.1 -0.6 -0.8 -0.1 0.5 -1.0 0.5 0.3
Comparative body size at age 10 0.3 0.8 2.7 -0.4 0.3 -0.5 -1.3 -0.2 -0.4 1.5 -0.6 -0.7 -0.6 1.0 -1.6 -0.9 0.1
Number of full brothers 0.4 0.5 2.1 0.1 -0.6 0.9 0.1 -0.9 0.1 -0.7 -1.3 0.5 -0.0 -0.2 -1.4 -0.0 -0.1
Worry too long after embarrassment 0.7 1.1 5.4 0.8 0.2 1.5 1.1 0.6 -0.6 -0.1 1.2 -0.4 1.5 -0.6 0.7 2.3 1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 2.2 2.9 7.9 1.8 -2.0 1.9 1.6 -1.8 -1.5 -2.4 -0.5 -1.9 1.5 -2.8 1.0 0.2 1.0
Wheeze or whistling in the chest in last year 0.6 1.1 2.7 -0.6 1.4 1.6 1.6 -0.0 0.7 -1.4 -0.3 -0.1 0.5 -0.4 -1.2 1.3 1.3
Number of children fathered 1.1 1.3 4.5 -1.4 0.9 -1.4 -0.7 -0.2 1.6 0.2 -0.1 1.5 -1.2 1.5 -2.1 -0.5 -0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 2.2 -0.9 -0.3 -1.0 0.2 1.5 -1.1 1.4 -0.6 -0.2 -0.1 0.1 -0.6 -1.3 0.8
Age at first live birth 2.2 3.8 13.6 -0.3 -1.3 -2.7 -3.7 1.0 -2.7 1.6 -2.3 0.8 -1.4 1.6 -2.0 -1.8 -1.8
Pulse wave peak to peak time 0.8 0.9 3.6 1.9 -0.2 1.1 0.0 0.2 0.6 0.8 1.5 0.4 1.2 0.5 0.9 1.2 -0.7
Health satisfaction 1.0 1.3 5.1 -1.2 2.2 -0.1 -0.3 1.4 0.4 -0.9 -0.8 -0.9 -0.9 0.4 1.9 -0.9 -1.0
Shortness of breath walking on level ground 1.1 1.3 4.0 -1.1 1.7 -0.9 -0.3 0.3 -0.8 -1.4 -2.0 -1.7 -0.7 0.3 -0.4 -1.4 -0.8
Qualifications: College or University degree 1.0 3.1 13.2 3.6 -3.0 0.1 -0.2 1.7 -1.7 1.4 1.8 0.5 2.0 0.8 1.8 -0.3 -1.6
Eye problems/disorders: None of the above 0.7 0.8 2.7 0.9 -0.0 -1.0 -0.6 0.8 0.2 -0.7 1.3 1.7 -0.1 1.4 0.5 -0.6 -1.2
Mouth/teeth dental problems: Loose teeth 1.0 1.1 2.8 0.7 -0.3 1.7 1.7 -1.2 1.1 -0.7 1.5 0.2 0.9 -0.3 -0.4 1.6 0.9
Emphysema/chronic bronchitis 0.6 0.6 3.5 -1.2 1.1 -0.2 -0.2 0.5 0.6 -0.8 -0.2 -0.9 -0.2 0.8 -1.9 0.4 0.2
Medication for pain relief, constipation, heartburn 1.5 2.6 8.4 -1.2 -1.5 -2.4 -2.9 1.4 0.4 1.9 0.1 1.4 -1.2 2.0 -2.0 -1.1 -0.3
Neck or shoulder pain in last month 0.5 0.7 3.8 1.4 0.1 0.8 0.8 -1.9 0.7 -0.4 0.7 -0.4 0.9 -0.7 0.0 -0.1 0.5
Medication: Blood pressure 1.4 2.4 7.9 -1.8 1.3 -0.6 -1.1 2.8 -1.0 0.3 0.4 1.9 -1.9 1.3 1.8 0.8 -2.2
Angina (self-reported) 0.6 0.8 2.8 -0.3 -0.3 0.7 0.8 -0.1 -0.7 -1.5 0.4 1.0 -0.8 -0.3 1.7 0.9 -1.3
Migraine (self-reported) 1.7 2.1 5.0 0.8 -2.2 1.7 1.5 -0.9 -1.5 -0.3 -1.8 -0.6 1.6 -2.2 1.2 0.5 1.6
Medication: Ibuprofen 2.7 3.2 13.5 2.5 -0.5 3.2 1.0 0.7 0.3 -0.6 2.4 -0.2 1.8 -1.4 3.7 1.3 0.2
Medication: Allopurinol 0.6 0.8 3.2 -0.2 0.6 -0.7 0.4 0.9 -1.8 -0.7 0.8 1.2 -0.6 0.8 0.6 -0.8 -1.2
Medication: Omeprazole 0.6 0.7 2.8 -1.2 1.0 0.0 1.7 0.5 0.1 0.3 0.4 -0.1 0.1 -1.0 1.4 0.2 1.2
Medication: Seretide 50 evohaler 1.6 1.9 8.8 -1.5 2.1 -0.4 -1.2 0.6 0.5 -0.4 -1.1 2.0 -3.0 0.5 -1.0 -0.0 -1.4
Mean time to correctly identify matches 0.7 1.2 6.7 -0.0 1.5 1.4 1.1 0.0 0.2 -1.1 0.6 -0.3 1.2 -0.8 0.3 2.6 1.2
Heart disease (mother) 0.2 0.2 1.0 0.1 -0.0 -0.5 0.4 0.6 0.1 0.2 0.0 0.6 0.3 -0.4 0.6 -1.0 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 3.3 -0.5 0.0 -0.3 -1.0 1.5 0.4 1.0 1.6 0.8 -0.1 1.8 -0.3 1.5 -0.2
Whole body fat mass 0.3 1.3 3.8 0.7 -0.3 1.9 1.1 -1.4 1.1 -0.9 0.2 -1.5 1.2 -1.5 0.1 1.2 1.2
Leg fat mass (right) 0.3 1.3 3.9 0.6 0.0 2.0 1.1 -1.1 0.9 -0.9 0.5 -1.5 1.2 -1.3 -0.2 1.4 1.3
Arm predicted mass (right) 0.1 0.3 1.1 0.4 -0.6 -0.3 -1.1 -0.2 0.2 0.8 0.2 -0.4 0.2 -0.2 -0.9 0.1 0.7
Pulse rate, automated reading 0.2 0.6 2.3 -0.2 1.2 0.3 -0.2 0.1 -1.5 0.5 -0.2 -1.1 0.4 -0.4 -1.0 0.9 0.8
Alcohol intake frequency. 1.2 2.9 10.5 -2.0 3.2 -1.4 -1.0 0.1 2.7 -0.6 -0.4 0.3 -2.2 1.9 -1.8 -0.5 -1.5
Comparative height size at age 10 0.1 0.7 3.3 -0.1 -0.1 -0.8 -1.8 1.0 -1.0 0.7 -0.1 -0.1 -0.8 1.1 -0.2 -0.4 -1.0
Number of full sisters 1.4 1.7 6.7 0.4 -0.3 2.0 1.3 -0.7 -1.5 -2.6 -1.1 -1.7 0.6 -1.6 -0.6 0.9 0.8
Suffer from ‘nerves’ 0.8 1.2 4.8 1.2 0.2 1.6 1.0 -0.9 0.8 -2.2 1.4 -0.2 1.4 -0.3 0.6 0.9 -0.1
Overall health rating 0.8 1.7 10.2 -1.9 3.2 0.7 1.7 -0.6 -0.0 -1.5 -1.0 -0.6 -1.4 -0.8 0.8 0.1 0.1
Chest pain or discomfort 1.2 1.8 5.1 -1.2 1.8 1.2 1.6 -1.1 -0.7 -2.3 -1.0 -0.4 -1.5 -2.1 0.7 1.0 0.3
Had major operations 3.5 4.1 11.0 1.6 -1.8 3.3 2.9 -1.3 0.7 -1.9 2.5 1.1 2.1 -1.5 0.5 3.2 1.7
Age at last live birth 1.6 2.3 7.7 -1.1 -0.2 -2.0 -2.8 1.6 -2.2 1.1 -1.8 0.2 -0.8 1.6 -2.1 -0.5 -0.4
Family relationship satisfaction 0.7 0.9 2.9 0.6 -0.8 0.4 -0.1 -0.9 -1.2 1.3 -1.7 -1.0 0.4 -1.1 0.4 -1.4 0.5
Leg pain on walking 1.0 1.2 6.8 0.2 -0.2 0.7 0.9 -1.6 0.0 -2.6 -1.2 -1.0 0.9 -1.1 1.2 0.1 -0.1
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.5 5.2 -1.1 1.1 -1.5 -1.3 0.1 -0.3 -2.3 -1.7 -0.3 -1.3 0.8 -0.8 -1.0 -1.4
Commuting to job workplace: Car/motor vehicle 0.9 1.1 6.3 1.8 -1.1 0.5 0.1 0.6 -1.5 0.1 0.6 0.2 0.9 -0.1 2.5 0.3 -0.6
Illness, injury, bereavement, stress in last 2 years 1.4 1.7 5.9 1.3 -1.5 -0.5 0.2 -0.3 -2.4 1.3 -0.8 -1.1 2.2 0.1 -0.5 -2.3 0.6
Medication: Aspirin 0.9 1.2 5.8 -0.1 1.1 0.7 1.1 0.3 -0.7 -1.3 -0.0 0.6 -0.4 -0.4 2.4 1.5 -1.9
Supplements: Vitamin C 1.2 1.4 3.2 0.9 0.2 1.7 1.7 -1.3 0.8 -1.8 1.0 -0.2 1.1 -0.8 -0.2 1.8 1.3
Knee pain experienced in last month 0.9 1.4 4.0 1.4 -0.4 1.8 1.3 -0.6 -0.2 -0.2 0.9 0.1 2.0 -1.4 1.5 1.3 1.0
Hypertension (Self-reported) 0.3 0.7 1.8 -0.9 1.3 -0.3 -0.9 1.4 -0.9 -0.1 0.3 0.8 -0.8 0.5 0.5 0.9 -1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.3 5.4 -1.1 -0.3 0.5 0.9 -0.7 -0.8 -0.0 -1.4 -2.3 0.7 -1.3 -0.5 0.3 2.3
Illnesses of father: Heart disease 0.4 0.5 1.5 0.6 -0.9 0.1 -0.3 1.1 -0.6 -1.2 0.4 -0.7 -0.1 -0.1 0.9 0.8 -0.8
Illnesses of siblings: Diabetes 0.3 0.4 1.7 -1.0 0.8 -0.6 -0.5 0.3 0.4 1.3 -0.7 0.6 -0.6 0.3 -0.0 0.2 0.1
Smoking status: Previous 0.4 0.6 1.5 -0.1 -0.3 1.1 1.1 -0.9 0.4 -1.1 -0.2 -0.1 0.1 -1.2 0.5 0.7 0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 4.4 1.7 -2.1 0.6 -1.0 0.2 -2.0 0.1 0.4 -0.5 0.6 -0.2 2.0 0.1 -0.7
Whole body fat-free mass 0.0 0.2 1.3 0.2 0.2 -0.4 -1.1 0.5 0.2 0.8 0.6 -0.0 -0.1 0.5 -0.6 0.2 0.1
Leg fat-free mass (right) 0.0 0.1 0.6 -0.2 0.5 -0.3 -0.8 0.0 0.5 0.4 0.4 -0.0 -0.3 0.2 -0.4 0.2 0.2
Arm fat percentage (left) 0.5 1.8 5.1 0.1 0.6 2.2 1.8 -1.8 2.3 -1.4 0.6 -0.8 0.6 -1.6 0.1 1.2 1.4
Average weekly red wine intake 0.5 0.7 2.1 -1.1 -0.2 -0.7 -0.5 0.4 1.1 1.3 -0.1 1.5 -1.1 0.5 -0.7 -0.7 0.1
Handedness (chirality/laterality): Left-handed 0.5 0.5 2.0 -1.1 -0.1 -0.5 1.4 -0.0 0.3 0.9 -0.2 0.1 0.0 -0.2 -0.4 -1.3 1.1
Mood swings 0.3 0.5 1.8 -0.2 1.3 0.5 0.8 0.9 -0.2 -1.2 0.1 -0.6 0.3 0.3 0.3 1.1 0.3
Loneliness, isolation 1.0 1.4 6.7 -1.7 1.5 -0.8 -0.7 -0.1 -1.7 -0.0 -1.3 -0.2 -0.7 0.1 -2.6 -1.0 1.1
Long-standing illness, disability or infirmity 1.0 1.6 3.6 -0.3 1.9 1.9 1.6 -0.7 -0.8 -1.9 0.2 0.1 -0.2 -1.3 1.6 1.8 -0.3
Ever had bowel cancer screening 1.4 1.6 6.9 -0.2 -0.4 1.7 2.6 -0.9 -0.2 0.8 -0.5 -0.1 0.8 -1.8 1.5 0.7 2.0
Diabetes diagnosed by doctor 0.1 0.2 0.5 -0.6 0.4 -0.0 0.3 0.0 -0.1 0.6 -0.2 -0.6 0.4 -0.2 0.7 0.0 0.7
Ever had stillbirth, spontaneous miscarriage or termination 2.5 2.7 7.2 -2.3 1.5 -1.7 -1.6 -0.2 0.8 -0.4 -1.7 -0.2 -2.4 1.0 -2.7 -2.6 -0.5
Friendships satisfaction 2.1 2.6 8.5 0.0 -0.9 -1.4 -2.9 -0.1 -2.6 1.6 -2.4 -0.4 -0.4 0.4 -0.8 -2.7 -0.9
Qualifications: nursing, teaching 0.3 0.4 1.7 1.3 -0.5 0.4 -0.8 -0.4 0.1 0.2 1.1 -0.4 0.6 -0.0 0.8 0.4 -0.6
Commuting to job workplace: Walk 0.9 1.0 4.6 -1.5 -0.4 -0.5 -0.2 -0.8 0.8 1.3 -0.5 -0.2 -1.0 -0.6 -2.1 -0.2 1.4
Eye problems/disorders: Cataract 0.4 0.4 2.0 -0.5 -0.2 0.4 0.3 0.2 0.0 1.4 0.2 -0.8 0.4 -0.8 0.0 1.1 0.7
Mouth/teeth dental problems: Mouth ulcers 1.5 2.4 6.6 -0.2 0.4 1.0 2.6 -2.5 0.9 -1.8 -1.7 -2.1 0.4 -2.2 -0.9 0.9 1.4
Medication for cholesterol 0.3 0.5 1.8 0.3 -0.5 0.4 -0.4 0.6 -0.8 -1.2 -1.4 -0.1 0.4 0.4 -0.9 -0.8 -0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 5.7 -1.2 1.3 0.3 2.4 -0.6 1.3 -0.2 -0.8 -0.6 0.0 -0.9 -0.5 0.6 1.6
Back pain experienced in last month 0.6 0.9 4.3 -0.0 0.5 0.6 1.5 -2.1 1.2 -0.7 -1.0 -0.9 0.6 -0.9 0.1 -0.3 0.7
Mineral and other dietary supplements 0.6 0.8 3.8 -0.2 0.7 -0.5 -1.7 1.9 0.3 1.6 -0.4 -0.5 -0.3 0.6 -0.3 -0.6 -0.7
Breast cancer (self-reported) 1.2 1.5 5.9 -1.4 1.0 -1.1 -1.0 0.9 -1.1 0.6 -2.2 -0.9 -0.8 0.9 -2.4 -0.1 0.1
Asthma (self-reported) 0.5 1.0 2.5 -1.3 1.6 -0.9 -0.3 1.1 1.5 -0.8 -0.4 0.7 -1.1 0.8 -1.3 -0.4 -0.4
Osteoporosis (self-reported) 0.6 0.8 3.2 0.9 -0.2 1.8 1.0 -0.9 0.2 -0.3 0.1 0.1 1.2 -0.4 0.3 1.8 0.6
Osteoarthritis (self-reported) 1.2 1.6 6.7 0.2 -1.5 1.8 1.2 -2.6 -0.3 -0.5 -1.5 0.6 -0.5 -2.2 -0.2 -0.2 0.6
Medication: Aspirin 1.3 1.7 10.1 0.9 0.5 0.9 1.1 0.5 -1.1 -1.2 0.7 0.9 0.0 -0.7 3.2 1.6 -1.9
Medication: Gliclazide 0.5 0.6 2.7 -1.6 1.4 -0.6 -0.8 0.3 -0.3 -0.6 -0.5 0.5 -1.1 0.2 -0.1 0.2 -0.6
Illnesses of father: None of the above (group 1) 0.7 0.9 3.4 -0.5 0.1 -0.8 -0.6 -1.0 1.6 0.2 1.3 1.8 -1.1 0.3 -0.7 -0.6 0.3
Smoking status: Current 0.5 0.8 2.8 -0.2 0.3 -0.6 0.1 -0.2 -1.3 0.2 -1.7 -1.6 0.1 0.3 -1.4 -1.2 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 2.2 1.5 -1.2 1.1 0.0 -0.3 -0.1 -0.1 0.6 -1.3 0.1 -0.6 0.5 -0.3 -0.6
Whole body water mass 0.0 0.2 1.4 0.1 0.3 -0.4 -1.2 0.3 0.3 0.6 0.5 -0.0 -0.2 0.5 -0.8 0.2 0.1
Leg predicted mass (right) 0.0 0.2 0.6 -0.2 0.5 -0.3 -0.8 0.0 0.6 0.4 0.5 -0.1 -0.3 0.2 -0.5 0.2 0.3
Arm fat mass (left) 0.3 1.2 3.4 0.2 0.2 1.8 1.2 -1.2 1.7 -0.7 0.7 -0.7 0.6 -1.3 -0.1 1.3 1.4
Number of self-reported non-cancer illnesses 1.2 2.0 8.7 0.2 -0.1 1.7 1.4 0.5 -0.2 -0.9 1.4 1.9 0.2 -1.0 2.6 3.0 -0.3
Average weekly champagne plus white wine intake 1.1 1.5 7.5 0.4 -0.1 0.0 1.0 0.7 2.7 0.7 1.7 2.2 -0.0 -0.4 1.2 0.8 1.0
Miserableness 0.6 1.0 4.3 -0.1 1.1 0.4 2.1 -1.2 -0.8 -0.0 -0.6 -1.1 0.5 -1.4 0.0 0.3 1.5
Guilty feelings 0.8 1.2 4.3 -0.6 0.8 1.1 2.1 -0.6 1.6 -0.3 0.9 -0.0 0.8 -0.7 -0.7 1.3 1.8
Wears glasses or contact lenses 0.7 0.8 3.1 0.6 -0.8 -0.1 0.6 1.6 0.0 1.1 1.0 -1.0 1.8 0.4 0.3 0.9 0.4
Ever taken oral contraceptive pill 0.6 0.6 2.0 -1.4 -0.3 -0.5 -1.2 -0.2 1.4 0.1 -0.3 -0.5 -1.4 -0.2 0.8 0.3 -0.3
Hearing aid user 1.8 2.0 6.1 0.2 -0.0 1.7 1.5 -2.4 0.9 -2.5 -1.6 -1.3 0.3 -1.9 0.2 1.1 0.9
Mother’s age at death 0.4 0.5 2.2 -1.1 0.9 -0.8 -0.1 -0.2 -0.3 0.2 0.1 -1.1 -0.0 0.5 -1.5 -0.1 0.2
Financial situation satisfaction 0.5 0.6 2.2 -1.5 1.2 0.2 0.3 0.5 0.1 -0.0 -0.7 -1.1 -0.9 -0.2 -0.5 -0.7 1.0
Tinnitus: Yes, now most or all of the time 0.8 1.0 3.3 -1.1 -0.2 0.4 1.5 -1.8 0.0 -0.5 -1.4 -0.3 -0.8 -1.4 0.8 -1.0 0.6
Commuting to job workplace: Public transport 0.6 0.7 3.1 0.7 -0.6 0.9 0.6 -0.5 1.0 0.1 1.8 1.4 0.8 -0.2 0.1 1.1 0.1
Eye problems/disorders: Glaucoma 1.4 1.7 4.3 -0.9 0.1 1.2 2.0 -1.7 1.3 -1.4 -0.5 -1.5 0.2 -1.9 -0.2 0.7 2.1
Medication: Blood pressure 0.3 0.5 1.5 0.4 0.2 0.2 0.2 -1.2 1.0 0.2 1.2 0.3 -0.1 -1.2 0.8 0.5 0.6
Pain type(s) experienced in last month: Hip pain 0.5 0.7 3.0 -0.6 0.4 -0.1 0.6 -1.1 1.2 -1.7 -0.4 -0.8 0.1 -0.2 -1.0 0.3 0.9
Supplements: Fish oil (including cod liver oil) 1.0 1.4 5.3 -1.1 0.1 -0.8 1.0 -2.3 -1.0 -2.1 -0.5 1.1 -1.4 -0.5 -1.3 -0.2 0.5
High cholesterol (Self-reported) 1.8 3.2 9.9 -2.3 3.1 -0.8 -0.5 0.6 1.6 -1.4 1.6 3.0 -3.1 0.4 0.3 1.0 -1.4
Medication: Bendroflumethiazide 0.7 1.1 3.4 0.4 0.2 -0.4 -1.2 -0.0 1.8 -0.6 0.9 0.7 -0.0 1.7 0.2 1.4 -1.7
Medication: Paracetamol 0.7 1.1 3.9 -0.5 2.0 1.0 1.1 -1.4 0.1 -1.8 -0.8 -1.3 -0.9 -0.9 0.0 -0.2 -0.1
Medication: Lisinopril 0.3 0.4 2.4 -0.8 1.6 0.0 -0.1 0.5 -0.5 0.4 -0.8 0.6 -0.9 -0.0 -0.2 0.3 -0.3
Medication: Atorvastatin 0.8 0.9 3.5 -0.6 0.8 0.2 -0.1 0.4 0.2 -1.7 -0.2 0.8 -1.7 -0.5 1.9 0.7 -1.0
Illnesses of father: High blood pressure 0.8 1.0 4.4 -0.3 -0.4 -0.2 -0.7 0.2 -1.2 2.1 -1.5 -1.3 -0.8 0.5 0.4 -0.9 -1.1
Alcohol drinker status: Never 0.7 0.8 2.8 0.2 0.8 0.0 -1.5 1.4 1.0 -0.7 -0.5 0.4 -0.4 1.3 -0.0 0.5 -1.7
Ever smoked 0.4 0.8 3.5 -1.1 0.5 -0.0 0.5 -1.1 -0.7 -1.3 -1.9 -1.0 -0.5 -0.6 -0.4 -0.3 0.5
Basal metabolic rate 0.0 0.2 0.7 0.1 0.3 -0.1 -0.8 0.1 0.5 0.5 0.6 -0.2 -0.1 0.2 -0.6 0.4 0.2
Leg fat percentage (left) 0.5 1.8 5.1 0.6 -0.3 2.3 1.7 -1.4 1.0 -1.0 0.0 -1.6 1.4 -1.9 -0.3 1.3 1.6
Arm fat-free mass (left) 0.0 0.2 0.8 0.3 -0.2 -0.1 -0.9 -0.1 -0.1 0.6 -0.1 -0.6 0.2 -0.2 -0.8 0.2 0.6
Number of operations (self-reported) 2.1 3.1 6.8 2.2 -2.1 2.6 2.1 -1.6 -1.1 -0.4 -0.0 0.4 2.4 -1.6 2.1 2.4 0.9
Average weekly beer plus cider intake 0.5 0.7 2.2 0.8 -0.5 0.6 0.6 -0.3 -1.2 -0.7 -1.1 -0.9 0.4 -1.5 1.1 -0.2 -0.1
Irritability 1.0 1.6 4.3 0.4 -1.4 1.4 2.1 -1.5 -1.3 -1.6 -0.1 0.7 0.4 -2.0 0.2 0.3 1.6
Risk taking 0.4 0.6 2.4 -1.3 -0.5 -0.8 0.3 -1.1 0.2 0.1 -0.6 -0.3 -1.1 -0.3 -0.6 -1.5 0.4
Ever had prostate specific antigen (PSA) test 0.7 0.8 4.2 -1.3 0.6 -1.0 -0.1 1.0 0.2 2.1 -0.0 -1.3 0.1 0.8 -0.5 -0.6 0.2
Fractured/broken bones in last 5 years 0.5 0.6 3.7 -0.9 -0.3 -0.1 0.1 -0.2 -0.3 0.0 -1.9 -0.8 -1.5 -0.4 0.4 -1.0 -0.2
Age started oral contraceptive pill 0.3 0.4 2.0 -0.1 -0.2 -0.5 -0.2 1.4 -0.5 0.9 0.3 0.2 -0.0 0.2 0.9 0.8 -0.3
Diastolic blood pressure, automated reading 0.3 0.9 4.2 0.5 -0.6 1.2 0.8 0.7 -0.1 -1.6 0.5 0.1 0.7 -0.8 -0.4 2.1 1.1
Ever depressed for a whole week 1.1 1.3 2.9 0.9 -0.6 1.7 1.4 -1.5 1.1 -1.6 -0.5 -0.7 1.4 -1.2 0.8 1.0 1.0
Unable to work because of sickness or disability 0.7 0.9 4.3 -1.0 1.5 0.1 -0.2 -0.1 0.3 -2.1 -0.5 0.3 -1.7 -0.4 -0.1 -0.0 -1.0
Commuting to job workplace: Cycle 0.3 0.4 1.9 0.4 -0.7 0.2 -0.9 0.2 0.8 -0.2 0.2 0.1 -0.1 0.5 -0.7 1.4 -0.9
Myopia 1.0 1.4 7.2 -0.3 -0.5 0.2 0.2 0.5 1.5 -1.0 1.1 2.7 -0.6 0.7 0.8 2.3 -0.8
Vascular/heart problems diagnosed by doctor 0.3 0.9 2.7 0.4 -1.3 0.2 0.8 -1.6 1.2 0.1 -0.4 -0.5 0.4 -0.3 -1.1 -1.4 1.4
Cholesterol lowering medication 0.8 1.2 3.8 -1.6 1.8 -1.0 -0.2 0.6 1.1 -0.4 1.1 1.8 -1.9 0.3 -0.2 -0.1 -0.6
Medication: Omeprazole (e.g. Zanprol) 1.3 1.5 4.6 -1.4 0.8 0.2 2.0 -0.5 -1.0 -0.2 -1.1 -2.2 0.3 -1.8 0.8 -0.6 1.8
Pain experienced in last month 0.9 1.6 4.0 -1.0 -0.7 -1.8 -2.0 1.3 0.6 -0.6 -0.7 0.2 -1.9 1.5 -0.0 -1.0 -2.0
Supplements: Calcium 0.2 0.3 1.1 -0.9 0.0 -0.3 1.0 -0.4 -0.3 -0.3 -0.3 -0.2 0.0 0.2 -0.1 -1.0 0.5
Basal cell carcinoma (self-reported) 0.9 1.1 3.0 0.7 -0.3 -0.9 -1.4 0.7 -0.6 0.6 0.3 1.7 0.1 1.7 0.2 -1.1 -1.7
Heart attack/myocardial infarction (self-reported) 0.7 0.9 3.8 -0.3 0.4 0.4 -0.1 1.1 -0.6 0.4 -0.1 1.5 -0.8 0.2 1.9 1.3 -1.5
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 4.1 0.3 0.4 0.1 -0.7 0.1 2.0 -0.5 1.0 -0.0 -0.1 0.6 0.1 0.8 -0.3
Heart disease (siblings) 0.9 1.1 4.2 1.2 -0.8 -0.1 -1.2 2.1 -0.7 1.5 1.2 0.2 0.3 0.6 1.6 -0.2 -1.1
Alcohol drinker status: Previous 1.4 1.6 4.8 -0.5 1.2 -1.6 -1.6 0.1 1.4 1.4 -0.3 -0.5 -0.5 2.1 -2.2 -0.8 -1.0
Pack years of smoking 0.8 1.2 5.0 -1.2 0.6 -0.5 0.4 -0.4 -1.2 -2.2 -1.6 1.5 -1.6 0.1 -0.2 0.1 -1.0
Impedance of whole body 0.1 0.7 2.4 1.1 -1.3 0.7 -0.3 -0.2 -1.6 0.1 -0.8 -0.6 0.9 0.1 0.9 0.6 -1.2
Leg fat mass (left) 0.3 1.3 3.6 0.6 -0.2 1.9 1.2 -1.2 0.8 -0.9 0.4 -1.3 1.2 -1.5 -0.1 1.4 1.3
Arm predicted mass (left) 0.0 0.2 0.8 0.3 -0.1 -0.0 -0.9 0.1 0.2 0.5 0.1 -0.4 0.3 -0.1 -0.7 0.3 0.5