Hub : Genes

NIT1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0860 0.0290 9.6e-04 0.066 0.011 0.054 0.057 0.074 1.7e-08 0.0130 3.2e-07 1.7e-07 2.5e-09
2 GTEx Adipose Subcutaneous 0.1600 0.0480 1.7e-05 0.056 NA 0.072 NA 0.060 2.4e-05 NA 1.7e-06 NA 1.1e-05
3 GTEx Colon Transverse 0.1710 0.0530 2.4e-04 0.098 NA 0.128 NA 0.115 2.2e-05 NA 1.1e-06 NA 4.3e-06
4 GTEx Muscle Skeletal 0.0808 0.0312 1.6e-03 0.016 NA 0.012 NA 0.014 9.5e-03 NA 2.2e-02 NA 1.5e-02
5 GTEx Nerve Tibial 0.0864 0.0351 3.8e-03 0.023 NA 0.031 NA 0.042 8.6e-03 NA 2.7e-03 NA 5.7e-04
6 GTEx Skin Not Sun Exposed Suprapubic 0.1190 0.0540 5.4e-03 -0.001 NA 0.012 NA 0.000 3.8e-01 NA 6.9e-02 NA 3.3e-01
7 GTEx Thyroid 0.1290 0.0530 1.4e-03 0.015 NA -0.002 NA 0.011 2.4e-02 NA 4.9e-01 NA 4.4e-02
8 METSIM Adipose 0.0532 0.0213 7.9e-04 0.001 0.014 0.014 0.015 0.003 2.6e-01 0.0026 3.3e-03 2.4e-03 1.1e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.8 1.2 5.1 0.4 -0.7 -2.3 1.2 -1.1 -0.3 -0.9 -0.8
Bipolar Disorder or Schizophrenia 0.4 0.9 5.2 0.2 0.1 -2.3 0.9 -1.1 -0.1 0.3 -0.4
Depressed Affect (Nagel 2018) 0.2 0.4 1.0 -1.0 -0.8 0.0 -0.8 0.2 -0.7 0.7 0.1
Depression (Nagel 2018) 0.5 0.8 1.4 -1.0 -0.3 1.1 -0.8 0.7 -1.2 0.9 0.9
Intelligence (Savage-Jansen 2018) 0.9 2.7 5.4 2.1 -1.2 -1.3 2.3 -2.0 -1.3 -1.2 -1.3
Neuroticism (Nagel 2018) 0.3 0.6 1.4 -0.2 -0.7 -1.0 0.3 -0.7 -1.2 0.3 -1.1
Schizophrenia (2018) 0.2 0.4 1.3 -0.1 0.6 -1.1 0.2 -0.5 0.1 1.1 0.1
Schizophrenia vs Biploar Disorder 4.0 5.2 8.6 -1.6 2.2 2.6 -2.4 2.7 0.2 2.9 2.3
Worry (Nagel 2018) 0.3 0.7 1.9 0.2 -0.7 -1.4 0.5 -0.9 -1.2 0.5 -0.6
Alzheimer’s Disease (in mother) 1.0 1.2 5.4 -0.4 -0.9 -2.3 0.2 -1.2 -0.5 0.6 -1.1
Alzheimer’s Disease (in father) 1.7 1.9 5.1 1.2 -1.9 -2.3 0.6 -1.3 -0.9 -0.3 -1.3
Alzheimer’s Disease (including proxy) 2.4 3.5 12.5 0.6 -2.2 -3.5 0.5 -2.0 -1.3 0.3 -1.9
Crohns Disease (2017) 4.1 9.0 16.6 -2.6 3.0 1.9 -3.3 3.1 3.5 4.1 1.9
Irritable Bowel Disease (IBD) 4.2 10.1 20.7 -2.4 3.6 1.2 -3.0 2.9 3.8 4.5 2.8
Ulcerative Colitis (UC) 2.5 4.6 10.8 -1.1 2.8 -0.1 -1.3 1.4 2.9 3.3 2.4
Major Depression (MDD) 0.3 0.4 0.9 0.7 -0.1 -0.8 0.8 -0.5 -1.0 0.3 0.4
Reaction Time 1.5 2.8 4.4 2.1 -1.4 -2.1 2.1 -1.9 -1.2 -1.4 -0.5
Verbal and Numeric Reasoning (VNR) 3.1 7.3 10.4 3.2 -2.6 -2.5 3.1 -3.0 -2.2 -2.8 -2.0
Breast Cancer 0.2 0.6 2.6 1.6 0.2 0.0 0.7 -0.5 0.4 0.2 -1.0
Ovarian Cancer 1.9 2.5 4.6 -1.0 1.1 2.1 -1.9 1.9 1.7 1.2 1.1
Prostate Cancer 0.5 0.7 2.6 -0.5 -0.7 0.5 -0.8 0.4 -1.6 1.0 -0.3
Age at First Birth 0.4 0.6 2.1 0.3 -1.4 -1.2 0.2 -0.6 0.9 -0.5 0.3
Bipolar Disorder (2011) 0.9 0.8 3.8 -0.6 -1.9 -1.0 -0.3 -0.9 0.0 -0.2 -0.7
Body Mass Index (BMI) (2010) 0.3 0.3 1.3 -0.1 0.5 1.0 -0.1 0.5 0.4 -0.0 1.1
Coronary Artery Disease (CAD) 2.7 3.2 5.7 1.2 -1.9 -1.8 2.1 -2.0 -0.1 -2.4 -1.7
Crohns Disease (2012) 2.9 4.7 7.5 -2.3 1.8 1.6 -2.7 2.1 2.6 2.6 0.9
Mean Putamen Volume 1.3 1.5 7.7 0.2 1.5 0.8 -0.3 0.8 2.8 0.5 0.4
Fasting Glucose 0.1 0.1 0.3 -0.1 0.3 0.1 0.2 -0.2 0.1 0.2 0.6
HbA1C 1.4 1.6 6.0 -0.5 2.4 1.2 -1.0 1.6 0.8 0.9 0.3
HDL Cholesterol 1.7 2.8 4.2 1.6 -2.0 -2.1 2.1 -1.9 -0.6 -1.8 -0.5
LDL Cholesterol 0.2 0.3 1.1 -1.1 -0.0 0.1 -0.6 0.6 0.5 0.6 -0.5
Lupus 0.5 0.7 1.7 -1.3 -0.1 -1.3 -0.6 -0.8 0.7 0.1 -0.7
Neuroticism (2016) 0.4 0.6 1.7 -1.1 0.5 -0.7 -0.7 0.3 -1.3 0.8 -0.2
Primary Biliary Cirrhosis 0.6 0.9 1.7 1.1 0.9 -0.5 1.3 -0.5 -1.1 -1.3 0.2
Rheumatoid Arthritis 1.2 1.7 3.8 -1.2 1.4 0.7 -1.1 1.4 0.7 1.9 1.3
Schizophrenia (2014) 0.1 0.3 1.8 0.2 1.3 -0.6 0.3 0.0 -0.4 0.4 -0.2
Triglycerides 1.9 3.1 5.4 -1.8 1.5 1.9 -2.2 2.3 0.8 1.8 1.1
Type 2 Diabetes (T2D) (2012) 1.0 1.1 1.9 -1.4 1.2 0.4 -0.8 0.9 1.2 1.0 1.3
Ulcerative Colitis 2.4 3.4 10.8 -0.3 3.3 0.4 -0.9 1.4 2.8 2.2 0.9
Blood Eosinophil Count 0.1 1.0 2.7 -0.2 1.5 1.6 0.7 1.6 0.3 -0.2 0.2
Blood Platelet Count 0.1 1.6 5.0 -1.6 -0.1 -0.1 -2.1 0.3 2.2 -0.1 0.9
Blood Red Count 0.8 7.8 14.1 -1.0 2.8 3.4 -1.9 3.5 3.8 2.4 2.8
Blood White Count 2.2 16.5 38.8 -1.5 6.2 5.3 -2.4 4.6 3.1 2.8 4.3
Heel T-Score 0.2 1.5 4.5 -0.9 0.2 -1.0 -0.8 0.3 1.7 1.4 2.1
BMI 0.5 2.7 6.0 -0.6 2.1 2.3 -0.8 1.8 1.2 0.2 2.4
Height 0.0 0.8 2.2 -1.4 -1.0 0.3 -0.4 0.3 1.5 -0.3 -0.7
Waist Hip Ratio (WHR) 1.9 8.4 20.0 1.7 -3.1 -4.5 2.5 -3.8 -2.1 -1.9 -2.7
Systolic Blood Pressure 0.2 0.8 2.4 -0.6 1.4 1.6 -0.5 0.5 0.5 0.4 0.6
Smoking Status 0.5 1.2 4.0 0.1 -1.4 -1.1 1.0 -0.9 -2.0 -0.9 -0.4
Allergy or Eczema 0.5 1.3 3.7 -0.3 1.1 1.5 -0.3 1.9 1.3 0.9 -0.8
Cardiovascular Disease 0.1 0.3 0.7 -0.5 0.2 0.9 -0.6 0.7 -0.6 0.2 0.6
Hypothyroidism (self reported) 0.7 1.6 7.7 0.8 1.5 0.5 -0.9 0.2 2.8 1.1 0.1
Respiratory disease 2.7 6.0 10.8 -2.4 3.3 2.6 -2.2 3.0 2.6 2.0 -0.2
Type 2 Diabetes (T2D) (2018) 1.6 2.9 4.6 -1.5 1.6 1.3 -2.1 1.7 0.8 2.1 2.0
Lung FEV1/FVC ratio 0.5 2.6 7.0 -0.0 -2.6 -0.9 1.1 -1.1 -2.5 -0.4 1.9
Lung FVC 0.9 4.4 13.1 2.1 -1.7 -1.4 2.2 -2.1 -3.6 -1.5 -0.9
Neuroticism 0.4 0.9 3.1 -1.8 0.6 -0.2 -1.1 0.8 -0.1 1.2 -0.1
Chronotype (morning person) 0.2 0.6 3.6 -0.4 -0.5 0.2 0.1 -0.2 1.9 -0.5 -0.4
Hair Pigment 0.1 1.5 3.6 -1.9 0.9 0.2 -1.3 0.7 1.3 1.8 -0.5
Tanning 0.1 0.8 2.2 1.5 -0.1 0.9 1.1 -0.2 -0.5 -1.3 0.1
Hand grip strength (left) 0.6 1.6 6.3 0.1 1.7 2.5 -0.3 1.6 0.5 0.4 0.7
Number of treatments/medications taken 0.8 1.5 2.8 -0.9 1.6 1.4 -1.0 1.5 1.7 0.4 -0.5
Average weekly spirits intake 0.5 0.6 1.8 -0.0 -0.9 -0.9 0.6 -0.7 -0.6 -1.4 -0.7
Sensitivity / hurt feelings 0.5 0.8 3.3 0.3 -0.3 -0.9 1.0 -0.8 -0.0 -0.7 -1.8
Frequency of depressed mood in last 2 weeks 1.4 1.9 3.4 -1.7 0.4 1.3 -1.9 1.5 -0.3 1.7 1.4
Hearing difficulty/problems: Yes 0.3 0.5 1.6 -0.2 0.2 1.2 -0.3 0.3 1.3 0.6 0.4
Relative age of first facial hair 0.3 0.5 1.1 -0.7 1.0 0.6 -1.0 1.0 -0.4 0.1 -0.4
Other serious medical condition/disability diagnosed by doctor 1.7 2.2 3.9 -2.0 1.7 1.5 -1.8 1.5 0.9 1.6 0.2
Ever used hormone-replacement therapy (HRT) 1.2 1.5 2.1 -1.1 1.4 1.2 -1.1 1.2 1.4 1.3 1.0
Ever had hysterectomy (womb removed) 0.7 0.8 1.5 1.0 0.0 -0.7 1.2 -1.2 0.6 -0.7 -1.1
Systolic blood pressure, automated reading 0.3 0.8 3.6 -0.6 1.9 0.9 -0.2 0.3 1.2 0.2 0.1
Eye problems/disorders: Diabetes related eye disease 1.5 1.6 5.0 -1.4 0.6 1.2 -1.0 1.2 0.4 1.2 2.2
Angina 1.0 1.3 4.7 -1.1 2.2 0.2 -0.6 1.0 1.7 0.1 0.2
Medication for hormone replacement therapy 1.1 1.2 2.7 -1.6 1.5 0.8 -1.1 1.5 -0.1 1.1 0.3
Vitamin and mineral supplements 3.4 4.6 7.8 1.7 -2.0 -2.4 1.8 -2.5 -2.2 -1.5 -2.8
Supplements: Zinc 1.9 2.1 3.3 -1.7 0.7 1.2 -1.8 1.7 1.6 1.2 1.3
Medication: Co-codamol 2.7 3.1 5.2 -1.9 2.0 1.4 -2.0 2.0 1.4 2.3 0.8
Medication: Metformin 1.1 1.5 4.0 -1.2 0.7 0.8 -1.8 1.1 -0.1 2.0 1.0
Diabetes (father) 0.2 0.3 0.7 0.3 -0.4 -0.7 0.1 -0.2 -0.3 0.8 -0.8
Diabetes (mother) 0.8 1.0 2.8 0.2 -1.7 -1.4 0.5 -1.4 -0.9 -0.5 0.1
Severe depression (siblings) 0.5 0.5 2.1 0.0 0.3 -1.5 1.0 -0.6 0.0 -0.5 0.3
Pack years adult smoking proportion 0.8 1.2 5.4 -0.9 0.1 -0.5 -0.9 0.1 2.3 1.3 0.6
Impedance of leg (right) 0.3 1.6 5.3 2.3 1.3 -0.8 1.4 -0.6 1.6 -0.4 -0.3
Leg fat-free mass (left) 0.4 1.9 5.9 -2.4 -0.3 1.1 -1.8 1.3 0.5 1.0 1.3
Trunk fat percentage 1.2 4.8 11.9 -0.7 3.5 2.3 -1.6 2.5 2.8 1.2 1.5
Hand grip strength (right) 0.9 2.5 7.0 -0.3 2.1 2.6 -0.5 1.9 1.3 0.9 1.2
Townsend deprivation index at recruitment 1.0 1.5 2.8 -1.1 0.8 1.1 -1.4 1.4 -0.6 1.2 1.7
Current tobacco smoking 0.2 0.3 1.3 -0.3 -1.1 -0.7 -0.2 -0.1 -0.2 0.2 0.7
Average weekly fortified wine intake 0.7 0.8 4.8 -0.3 0.0 -1.0 0.2 0.1 2.2 0.2 0.6
Maternal smoking around birth 0.4 0.6 2.0 -0.4 1.4 -0.2 0.1 0.0 -0.1 -1.0 -1.2
Fed-up feelings 0.2 0.5 0.9 -0.9 -0.9 -0.4 -0.7 -0.2 -0.7 0.8 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.7 2.2 5.1 -1.4 0.7 1.9 -1.5 1.6 -0.4 1.4 2.2
Relative age voice broke 0.2 0.3 1.1 -1.1 0.1 -0.2 -0.8 0.4 -0.1 -0.1 0.4
Taking other prescription medications 0.9 1.5 6.0 0.2 1.6 1.3 -0.2 1.0 2.5 0.7 0.1
Age when periods started (menarche) 0.9 2.3 4.1 -1.1 2.0 0.4 -1.8 1.5 1.3 1.8 1.4
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 1.4 -0.1 0.0 -0.2 0.1 -0.3 0.3 0.0 -1.2
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 3.2 -1.2 1.1 0.7 -0.9 1.2 0.9 0.6 1.8
Tinnitus: Yes, but not now, but have in the past 2.3 2.4 4.5 1.5 -2.1 -1.5 1.3 -1.9 -1.3 -1.7 -0.6
Qualifications: CSEs or equivalent 2.2 2.9 5.1 -1.3 2.1 1.0 -1.9 1.7 1.7 2.3 1.3
Serious illness, injury or assault to yourself 0.5 0.6 2.8 -0.3 -0.4 0.9 -0.5 0.5 -1.7 0.1 0.5
High blood pressure 0.4 1.0 2.1 -1.3 1.3 0.8 -1.4 0.7 0.6 1.2 0.3
Hayfever, allergic rhinitis or eczema 0.8 1.7 4.0 -0.5 1.4 1.6 -0.9 2.0 1.4 1.5 -0.1
Multivitamins +/- minerals 1.8 2.3 5.0 -0.7 1.3 2.0 -1.1 2.2 0.8 0.9 2.1
Stomach or abdominal pain in last month 1.5 1.9 2.9 -1.2 1.5 1.6 -1.3 1.7 0.9 1.4 1.3
Supplements: Glucosamine 0.8 1.0 5.8 0.1 0.6 0.3 0.4 0.4 2.4 -1.1 0.4
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 1.4 -0.5 1.2 0.4 -0.5 0.9 0.7 0.5 -0.1
Medication: Atenolol 3.6 4.5 6.8 -2.6 1.5 2.3 -2.6 2.1 1.7 2.5 1.1
Medication: Levothyroxine sodium 4.3 7.2 14.1 -2.0 3.1 2.4 -3.2 2.4 3.8 2.4 1.5
Sitting height 0.0 0.3 1.2 -0.0 0.1 -0.4 0.3 -0.3 0.9 -0.3 -1.1
Chronic bronchitis/emphysema (father) 1.4 1.7 3.4 1.6 -0.4 -1.1 1.9 -1.2 0.3 -1.7 -1.4
High blood pressure (mother) 0.6 0.9 5.0 0.2 -0.5 0.1 0.3 -0.5 -1.1 -0.5 -2.2
Body mass index (BMI) 0.6 2.6 3.6 -1.4 1.8 1.9 -1.6 1.9 1.3 1.1 1.8
Impedance of leg (left) 0.4 1.8 6.4 2.5 1.2 -1.1 1.7 -0.9 1.0 -0.5 -0.6
Leg predicted mass (left) 0.4 2.0 6.2 -2.5 -0.3 1.1 -1.9 1.4 0.5 1.0 1.4
Trunk fat mass 1.2 5.3 9.4 -1.4 3.1 2.5 -2.0 2.7 2.9 1.4 1.8
Waist circumference 0.2 0.7 1.3 -1.1 0.6 0.5 -1.0 0.8 0.9 0.5 1.0
Number of incorrect matches in round 0.7 1.1 4.0 -0.4 -0.2 2.0 -1.1 1.1 -1.2 0.6 0.9
Past tobacco smoking 0.3 0.6 1.9 1.4 -0.7 -0.5 0.5 -0.6 0.4 -0.7 -1.0
Alcohol usually taken with meals 1.1 1.8 5.5 0.7 -1.1 -1.3 1.2 -1.1 2.4 -1.3 -1.0
Nervous feelings 0.5 0.9 4.1 -0.4 0.7 -0.9 -0.7 0.3 0.8 2.0 0.1
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.3 2.2 -0.7 0.6 1.4 -1.5 1.2 -0.5 1.4 1.4
Hearing difficulty/problems with background noise 0.6 0.9 2.0 -1.3 0.3 0.4 -0.9 0.3 1.1 1.2 1.4
Hair/balding pattern: Pattern 2 0.2 0.3 0.6 -0.5 -0.2 0.7 -0.5 0.1 0.3 0.7 0.8
Had menopause 0.3 0.3 1.8 -0.5 -0.1 -0.5 0.1 -0.1 1.4 -0.2 0.5
Had other major operations 4.3 5.2 8.1 -2.4 2.5 1.8 -2.4 2.1 2.8 2.5 1.3
Forced vital capacity (FVC) 0.2 0.6 3.0 -0.4 -0.1 0.7 -0.4 0.3 -1.7 0.9 0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.2 2.3 -1.2 1.5 1.1 -0.9 1.5 0.8 0.2 1.1
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 1.7 -1.3 1.0 0.9 -1.1 1.1 0.7 1.3 0.6
Qualifications: None of the above 0.1 0.2 0.8 0.3 -0.1 0.6 0.1 -0.3 -0.9 -0.5 -0.3
Financial difficulties in last 2 years 1.4 1.9 6.2 -0.8 0.4 0.4 -1.9 0.8 0.5 2.5 1.8
Mouth/teeth dental problems 0.4 0.7 2.5 0.1 -0.2 1.6 -0.6 0.6 -0.8 -0.2 1.2
Heart attack 0.5 0.7 1.6 -0.9 1.3 1.0 -0.4 1.1 0.7 0.4 -0.1
Allergy 1.3 2.9 5.3 1.1 -2.2 -1.7 1.1 -2.3 -2.2 -1.7 0.1
Pain all over the body in last month 1.8 1.9 5.2 -1.1 2.3 1.6 -1.6 1.2 0.5 1.3 0.5
Diabetes (self-reported) 2.5 3.8 6.4 -1.9 1.4 1.8 -2.3 2.1 0.0 2.4 2.5
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.6 -0.6 0.1 0.7 -0.6 1.3 0.4 0.8 -0.2
Medication: Ramipril 0.4 0.5 1.2 0.9 1.0 0.5 0.6 0.1 0.1 -1.1 0.1
Medication: Simvastatin 1.7 2.5 5.1 -1.4 1.6 1.7 -1.6 2.2 0.4 1.7 1.3
Fluid intelligence score 4.6 9.5 13.1 3.3 -2.9 -2.8 3.6 -3.5 -2.0 -3.4 -2.8
Illnesses of siblings 1.9 2.6 7.1 1.7 -2.7 -1.7 1.5 -1.6 -1.4 -1.1 -0.7
Neuroticism score 0.2 0.4 1.4 -0.5 -0.4 -0.5 0.0 -0.3 -1.0 0.1 -1.2
Weight 0.7 3.4 4.8 -2.1 1.5 2.1 -2.0 2.2 1.7 1.2 1.8
Impedance of arm (right) 0.2 0.7 3.1 1.0 1.8 -0.0 -0.1 0.4 0.4 0.4 -1.0
Arm fat percentage (right) 1.1 4.2 8.2 -1.1 2.9 2.4 -1.8 2.5 1.9 1.5 1.7
Trunk fat-free mass 0.2 1.4 5.8 -2.4 -1.3 0.7 -1.3 0.9 0.0 0.5 0.9
Hip circumference 1.4 6.1 8.7 -2.4 2.0 2.9 -2.7 3.0 2.3 1.8 2.6
Time employed in main current job 0.5 0.6 1.4 -0.2 1.1 0.7 -0.5 0.9 -0.3 1.2 -0.0
Alcohol intake versus 10 years previously 1.2 1.7 4.1 -0.9 2.0 1.3 -0.7 1.4 1.1 1.1 1.6
Father’s age at death 0.7 1.0 2.8 1.2 -0.7 -1.7 1.1 -1.0 -0.3 -0.6 -0.6
Worrier / anxious feelings 1.1 2.1 6.0 1.6 -0.4 -0.9 1.6 -1.1 -1.7 -0.9 -2.4
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.9 3.1 -0.0 0.6 1.8 -1.2 1.0 -0.3 0.8 0.5
Falls in the last year 0.1 0.2 0.5 -0.6 -0.0 -0.0 -0.5 0.2 -0.7 0.5 -0.3
Hair/balding pattern: Pattern 3 0.6 0.9 3.5 -0.9 -0.9 -0.6 -0.4 -0.1 -1.9 0.2 1.4
Number of live births 0.4 0.6 2.6 -0.1 -1.2 -0.7 0.4 -0.6 -1.6 0.2 0.3
Forced expiratory volume in 1-second (FEV1) 0.4 1.3 5.7 -0.7 -1.3 0.5 -0.4 -0.0 -2.4 0.9 1.3
Pulse rate 0.2 0.3 0.6 -0.2 0.3 0.3 -0.8 0.4 -0.7 0.5 0.6
Happiness 0.6 0.8 3.6 -0.5 -0.9 0.5 -0.6 0.4 -1.9 0.2 0.9
Noisy workplace 1.3 1.5 4.2 -0.0 1.8 2.0 -1.2 1.3 0.1 1.2 0.5
Qualifications: A levels/AS levels or equivalent 1.5 3.3 7.0 1.1 -2.3 -2.6 1.5 -1.9 -1.7 -1.3 -1.6
Serious illness, injury or assault of a close relative in last 2 years 1.5 1.7 4.2 0.7 -1.4 -0.8 0.4 -0.5 -1.9 -1.6 -2.0
Mouth/teeth dental problems: Dentures 0.5 0.9 2.5 -0.8 0.8 1.6 -0.4 1.1 1.4 0.3 0.4
Asthma 3.3 6.5 10.9 -2.5 3.3 2.9 -2.0 3.1 2.8 2.1 0.8
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 1.8 0.2 1.1 1.4 -0.2 0.9 0.8 -0.3 0.2
Medication: Cholesterol lowering 0.4 0.6 1.1 -0.8 0.8 1.0 -0.5 1.0 -0.8 0.4 -0.3
Depression (self-reported) 0.1 0.1 0.4 0.7 0.0 0.2 0.1 0.1 0.1 0.2 -0.5
Medication: Lansoprazole 0.8 0.9 2.0 1.4 -1.0 -0.7 0.6 -0.8 -1.0 -0.3 -1.4
Prospective memory result 3.3 4.1 5.9 -1.6 2.3 1.8 -2.0 2.3 0.9 2.4 2.4
Lung cancer (father) 0.8 0.9 2.5 1.4 -0.1 -0.4 1.2 -0.9 0.6 -1.6 -0.3
Illnesses of mother 0.6 0.7 3.1 0.3 -0.0 1.0 -0.1 0.7 -0.9 0.0 1.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 6.5 -0.0 -1.3 0.0 -0.2 -0.3 -2.5 0.8 0.7
Pulse wave Arterial Stiffness index 0.8 0.9 2.3 -1.3 1.5 0.2 -0.8 0.6 1.1 0.8 0.3
Impedance of arm (left) 0.2 0.9 4.0 0.8 2.0 0.1 -0.2 0.5 1.2 0.7 -0.7
Arm fat mass (right) 0.7 3.0 4.6 -1.3 2.0 2.1 -1.7 2.1 1.6 1.1 1.6
Trunk predicted mass 0.3 1.4 5.7 -2.4 -1.3 0.7 -1.4 0.9 -0.0 0.5 0.8
Standing height 0.0 0.5 1.7 -1.3 -0.5 0.2 -0.6 0.5 1.1 0.1 -0.3
Length of working week for main job 0.5 0.6 2.0 0.6 -0.1 0.8 -0.5 0.6 -1.4 -0.1 -0.9
Exposure to tobacco smoke at home 0.8 0.9 3.0 -0.0 1.7 1.6 -0.1 0.7 -0.9 0.1 -0.7
Breastfed as a baby 0.2 0.3 0.7 -0.4 0.5 0.2 -0.3 -0.0 -0.8 -0.8 -0.6
Tense / ‘highly strung’ 0.2 0.3 0.7 -0.8 0.8 -0.2 -0.5 0.2 0.2 0.9 0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 1.8 1.1 -0.7 -0.9 1.3 -0.8 -0.0 -0.9 -0.4
Hair/balding pattern: Pattern 4 0.6 1.5 4.9 1.8 0.5 -0.1 1.2 -0.3 2.2 -0.6 -1.2
Birth weight of first child 1.3 2.3 4.0 1.0 -1.9 -2.0 1.1 -2.0 0.9 -1.6 -1.3
Peak expiratory flow (PEF) 0.4 1.0 5.1 -0.1 -1.3 0.2 0.8 -0.6 -2.2 -0.4 0.4
Pulse wave reflection index 0.3 0.3 1.1 -0.1 1.0 -0.2 0.3 -0.3 0.1 -0.4 -1.1
Ever highly irritable/argumentative for 2 days 0.2 0.2 0.6 -0.4 0.2 0.3 -0.1 0.3 0.8 0.8 -0.3
Loud music exposure frequency 0.3 0.4 0.8 -0.5 -0.7 -0.6 0.6 -0.8 -0.9 -0.3 -0.1
Qualifications: O levels/GCSEs or equivalent 0.5 0.7 1.3 0.8 -1.1 -0.9 0.1 -1.0 0.8 -0.1 -1.1
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 3.0 0.1 -0.5 -1.7 0.6 -1.0 -1.5 -0.3 -1.3
Blood clot in the leg (DVT) 1.1 1.4 2.8 1.6 -0.5 -1.7 1.6 -1.3 -1.1 0.0 -0.5
Medication: Paracetamol 3.0 4.9 7.5 -1.8 2.5 2.5 -2.5 2.7 1.2 2.5 1.6
Headache pain in last month 3.9 6.7 11.7 -2.5 2.0 3.0 -3.4 2.8 1.4 3.4 1.3
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 1.3 1.1 -0.4 -1.1 1.1 -0.9 0.1 -0.8 -0.6
Glaucoma (self-reported) 0.5 0.6 3.0 -0.4 1.7 0.1 -0.5 0.6 0.6 0.6 0.1
Gout (self-reported) 1.0 1.3 2.5 -1.5 0.8 0.7 -1.1 1.3 1.6 0.9 1.0
Hypothyroidism/myxoedema (self-reported) 1.1 2.1 8.1 0.4 2.2 1.0 -1.3 0.6 2.8 0.8 0.1
Medication: Amlodipine 1.6 2.2 3.8 -1.9 1.7 1.8 -2.0 1.8 -0.4 0.8 0.6
Medication: Ventolin 100micrograms inhaler 3.6 4.6 7.1 -1.9 1.8 2.7 -2.4 2.7 1.8 2.3 1.2
Birth weight 0.8 1.8 5.8 -1.0 1.5 2.4 -1.5 1.6 0.3 0.3 0.7
Chronic bronchitis/emphysema (mother) 0.2 0.3 1.6 -0.4 1.3 0.2 -0.2 0.3 0.5 -0.1 -0.3
High blood pressure (siblings) 3.0 4.3 6.1 -1.9 2.5 2.1 -2.1 2.1 1.7 2.2 1.9
Forced vital capacity (FVC), Best measure 0.1 0.5 3.0 0.2 -0.4 0.4 -0.1 -0.1 -1.7 0.7 0.2
Body fat percentage 1.5 5.9 13.3 -0.9 3.6 2.5 -1.8 2.7 3.1 1.4 2.1
Leg fat percentage (right) 1.4 5.0 11.8 -0.8 3.4 2.2 -1.5 2.4 3.1 1.1 2.1
Arm fat-free mass (right) 0.2 1.1 4.2 -2.0 -0.7 0.6 -1.1 0.8 0.4 0.5 1.2
Exposure to tobacco smoke outside home 0.4 0.6 1.3 1.1 -0.2 -0.3 0.7 -0.9 -1.0 -0.5 -0.7
Comparative body size at age 10 0.3 0.9 2.2 0.6 -1.4 1.5 -0.1 -0.2 -0.6 -0.6 1.4
Number of full brothers 0.4 0.5 1.2 1.1 0.6 -0.6 0.3 -0.2 -1.1 0.5 -0.6
Worry too long after embarrassment 1.8 3.0 6.1 1.0 -1.1 -2.1 1.8 -1.9 -1.1 -1.7 -2.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.4 1.8 4.7 1.0 -1.4 -2.2 1.6 -1.5 -0.0 -1.1 -1.0
Wheeze or whistling in the chest in last year 1.0 1.8 3.3 -1.4 1.2 1.8 -1.8 1.8 -0.2 0.8 0.8
Number of children fathered 4.1 4.6 8.8 -2.1 2.3 3.0 -2.1 2.6 2.3 1.4 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 1.2 -0.8 -0.1 0.3 -0.7 0.3 -1.1 0.8 0.1
Age at first live birth 3.2 5.7 10.5 2.3 -3.2 -2.5 2.7 -2.5 -0.6 -2.6 -1.7
Pulse wave peak to peak time 0.9 1.0 2.9 1.2 -1.7 -0.3 0.8 -0.7 -1.2 -0.9 -0.4
Health satisfaction 2.7 3.6 7.6 -2.4 0.4 1.9 -2.8 1.9 -0.0 2.5 1.5
Shortness of breath walking on level ground 3.0 3.6 8.2 -1.6 0.7 1.9 -2.9 2.2 1.4 2.1 1.6
Qualifications: College or University degree 0.5 1.7 4.2 0.8 -1.6 -1.3 1.4 -1.0 -0.5 -2.1 -1.1
Eye problems/disorders: None of the above 1.3 1.4 4.0 1.2 -2.0 -1.0 1.2 -1.4 -1.1 -0.7 -0.5
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.6 -0.3 0.5 1.3 -0.2 1.2 -0.9 0.2 -0.8
Emphysema/chronic bronchitis 0.3 0.4 0.9 -0.3 0.8 -0.6 -0.3 -0.5 0.7 1.0 0.1
Medication for pain relief, constipation, heartburn 2.0 3.4 5.5 1.1 -2.3 -2.3 1.8 -2.2 -2.1 -1.3 -1.0
Neck or shoulder pain in last month 0.6 0.9 1.7 -1.1 0.7 1.2 -1.0 1.2 0.1 1.3 -0.0
Medication: Blood pressure 1.6 2.9 4.3 -2.1 1.3 1.9 -2.1 1.7 1.0 1.7 1.6
Angina (self-reported) 0.8 1.0 3.5 -1.1 1.9 0.2 -0.6 0.8 1.6 -0.1 0.1
Migraine (self-reported) 0.1 0.1 0.3 -0.6 -0.4 0.1 -0.1 -0.2 0.1 -0.1 0.1
Medication: Ibuprofen 0.3 0.3 1.4 0.0 0.7 1.2 -0.4 0.7 0.5 0.2 0.2
Medication: Allopurinol 0.2 0.2 1.7 0.3 -0.1 0.2 0.0 0.3 1.3 0.2 -0.0
Medication: Omeprazole 0.9 1.1 2.4 -1.5 1.1 0.6 -1.4 0.8 1.6 -0.0 -0.4
Medication: Seretide 50 evohaler 1.6 1.9 4.3 -0.9 1.0 2.1 -1.3 1.9 -1.4 1.2 0.4
Mean time to correctly identify matches 1.4 2.6 4.9 2.0 -0.6 -2.0 2.2 -1.8 -0.1 -1.8 -1.0
Heart disease (mother) 0.2 0.3 0.9 -0.1 -1.0 -0.5 0.2 -0.7 0.4 -0.3 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.2 1.4 5.3 -1.4 0.3 0.7 -0.9 0.7 0.8 1.3 2.3
Whole body fat mass 1.2 5.0 7.3 -1.6 2.7 2.3 -2.0 2.6 2.7 1.5 2.1
Leg fat mass (right) 1.2 4.6 7.5 -1.5 2.5 2.1 -1.9 2.3 2.7 1.4 2.5
Arm predicted mass (right) 0.3 1.3 4.5 -2.1 -0.6 0.7 -1.3 0.9 0.5 0.8 1.4
Pulse rate, automated reading 0.1 0.5 1.4 0.9 -0.1 -0.3 0.4 -0.6 -0.8 -0.5 -1.2
Alcohol intake frequency. 0.4 0.8 1.7 -0.6 1.0 0.9 -0.9 0.9 -0.1 1.3 1.2
Comparative height size at age 10 0.1 0.6 3.8 -0.6 0.2 0.6 0.2 0.2 2.0 0.0 0.6
Number of full sisters 2.6 3.2 5.0 -1.8 2.2 1.7 -1.9 2.0 0.9 1.2 2.0
Suffer from ‘nerves’ 0.2 0.4 0.9 0.7 0.7 -0.7 -0.1 -0.4 1.0 0.5 0.5
Overall health rating 3.6 7.7 11.7 -2.6 3.4 3.3 -3.2 2.8 2.2 2.8 1.3
Chest pain or discomfort 0.7 1.0 2.9 -1.7 1.2 0.0 -1.0 0.5 1.1 0.6 1.0
Had major operations 0.7 0.9 1.9 -1.0 0.4 0.9 -0.9 1.0 1.4 0.5 1.0
Age at last live birth 3.0 4.4 7.4 1.9 -2.7 -2.4 2.3 -2.2 -0.9 -2.4 -1.4
Family relationship satisfaction 0.5 0.7 2.6 1.6 -0.4 -0.0 0.2 -0.3 -0.8 -0.5 -1.2
Leg pain on walking 0.5 0.6 2.3 0.0 0.1 -0.7 -0.5 -0.0 1.5 0.5 1.1
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.6 -0.7 0.2 0.2 -0.0 0.0 0.5 0.8 0.5
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.6 0.1 0.2 0.8 -0.3 0.2 0.4 0.7 0.5
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.1 0.6 -0.4 -1.0 1.1 -1.0 0.8 -0.7 -0.4
Medication: Aspirin 1.0 1.4 2.8 -0.7 1.5 1.7 -0.9 1.5 0.9 0.1 1.2
Supplements: Vitamin C 3.9 4.6 9.1 -1.9 2.6 2.0 -2.1 2.0 3.0 1.6 1.2
Knee pain experienced in last month 1.0 1.5 3.6 -1.9 -0.0 0.8 -1.5 0.8 1.8 1.1 0.7
Hypertension (Self-reported) 0.2 0.6 1.3 -1.1 1.1 0.6 -1.1 0.5 0.3 0.9 0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.5 1.7 3.6 -1.2 1.1 1.9 -1.5 1.3 1.3 1.1 0.7
Illnesses of father: Heart disease 1.7 2.4 4.0 -1.3 1.7 0.9 -2.0 1.8 1.6 1.8 0.7
Illnesses of siblings: Diabetes 0.2 0.3 0.7 -0.7 0.0 0.5 -0.8 0.3 -0.3 0.7 0.5
Smoking status: Previous 0.5 0.8 2.5 -1.6 1.0 0.5 -0.6 0.8 0.0 0.9 0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 0.8 -0.6 -0.0 0.8 -0.3 0.9 0.5 0.1 0.6
Whole body fat-free mass 0.3 1.6 6.1 -2.5 -0.9 0.8 -1.5 1.1 0.1 0.7 1.0
Leg fat-free mass (right) 0.3 1.7 5.8 -2.4 -0.5 1.0 -1.7 1.2 -0.0 1.0 1.0
Arm fat percentage (left) 1.2 4.9 9.7 -1.2 3.1 2.4 -1.9 2.6 2.3 1.7 2.0
Average weekly red wine intake 0.1 0.2 0.5 -0.7 0.1 0.2 -0.6 0.7 0.2 0.2 0.6
Handedness (chirality/laterality): Left-handed 0.7 0.8 2.3 0.8 -1.5 -0.5 0.6 -1.0 -1.0 -0.7 0.7
Mood swings 0.6 1.1 2.2 -1.4 -1.1 0.8 -1.3 0.9 -0.4 1.5 0.4
Loneliness, isolation 1.2 1.7 4.2 -2.1 -0.3 1.1 -2.0 0.5 0.4 1.1 1.6
Long-standing illness, disability or infirmity 3.1 4.8 9.3 -1.6 3.0 2.3 -2.0 2.2 1.9 2.2 1.9
Ever had bowel cancer screening 0.5 0.5 1.2 1.1 0.7 -0.6 0.8 -0.8 0.3 0.2 -0.9
Diabetes diagnosed by doctor 1.1 1.9 3.1 -1.2 1.1 1.1 -1.7 1.4 -0.1 1.8 1.8
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 2.1 -1.5 0.5 0.8 -0.8 1.0 -0.4 0.8 0.9
Friendships satisfaction 0.3 0.4 1.1 0.4 -0.7 0.3 -0.2 -0.4 -1.1 -0.8 0.2
Qualifications: nursing, teaching 0.8 1.2 3.5 0.6 -0.2 -1.0 1.2 -1.0 -0.9 -1.3 -1.9
Commuting to job workplace: Walk 0.2 0.2 0.8 -0.6 -0.9 -0.2 -0.0 0.3 0.1 0.2 0.3
Eye problems/disorders: Cataract 0.5 0.6 1.7 -0.9 1.3 0.5 -1.0 0.7 0.1 0.3 -0.8
Mouth/teeth dental problems: Mouth ulcers 1.0 1.6 10.1 -0.3 -0.6 -3.2 0.3 -1.1 0.3 0.3 -0.8
Medication for cholesterol 0.4 0.6 3.2 0.5 -1.8 -0.7 0.5 -0.6 0.1 -0.0 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.5 1.7 3.4 -1.0 1.8 1.6 -0.7 1.5 1.8 0.7 0.5
Back pain experienced in last month 0.4 0.6 2.8 -0.9 0.7 -0.2 -0.3 0.2 -0.1 1.7 0.9
Mineral and other dietary supplements 2.5 3.4 6.7 0.9 -1.6 -2.1 1.0 -2.2 -2.6 0.5 -2.5
Breast cancer (self-reported) 2.5 3.0 5.2 1.4 -2.0 -0.8 1.4 -1.3 -1.8 -2.3 -2.2
Asthma (self-reported) 3.4 6.7 12.4 -2.4 3.5 3.0 -2.1 3.2 2.7 2.2 0.6
Osteoporosis (self-reported) 1.1 1.3 2.5 -0.9 0.5 1.2 -1.6 0.8 1.2 1.1 1.6
Osteoarthritis (self-reported) 3.7 4.8 10.8 -3.3 1.2 2.0 -2.7 2.1 1.6 2.0 1.9
Medication: Aspirin 0.5 0.7 1.5 -0.4 1.2 1.0 -0.5 1.0 0.8 -0.5 0.8
Medication: Gliclazide 0.5 0.5 3.8 0.4 0.1 0.1 0.3 -0.1 -1.9 -0.5 0.2
Illnesses of father: None of the above (group 1) 2.6 3.2 5.8 1.5 -2.4 -1.4 1.7 -2.1 -1.9 -1.8 -1.1
Smoking status: Current 0.2 0.3 1.0 -0.4 -0.9 -0.4 -0.1 0.1 -0.3 0.2 1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.8 0.0 1.0 0.6 0.0 0.3 -1.3 1.1 -0.0
Whole body water mass 0.3 1.7 6.6 -2.6 -0.9 0.9 -1.6 1.1 0.1 0.7 1.1
Leg predicted mass (right) 0.3 1.5 5.3 -2.3 -0.6 0.9 -1.6 1.1 -0.0 0.9 1.0
Arm fat mass (left) 0.9 3.5 5.0 -1.4 2.2 2.2 -1.8 2.2 1.9 1.1 1.9
Number of self-reported non-cancer illnesses 0.2 0.3 0.7 -0.6 0.8 0.0 0.1 0.1 0.8 0.6 -0.7
Average weekly champagne plus white wine intake 0.5 0.6 1.1 0.4 -1.0 -1.1 0.7 -0.7 -0.7 -0.5 -0.9
Miserableness 0.7 1.2 2.2 0.6 -1.5 -1.3 0.9 -1.3 -1.5 -0.7 -0.5
Guilty feelings 0.5 0.8 3.6 -0.6 -0.4 -0.5 0.6 -0.0 -1.9 -0.1 -1.3
Wears glasses or contact lenses 0.8 1.0 3.4 -0.9 0.0 -0.8 -0.7 -0.0 1.9 1.0 -1.1
Ever taken oral contraceptive pill 0.2 0.2 0.5 0.2 0.7 0.4 0.5 0.7 0.1 -0.1 -0.1
Hearing aid user 0.9 1.0 2.4 0.2 -1.2 -1.6 0.2 -1.3 1.3 0.2 0.5
Mother’s age at death 0.4 0.5 1.5 -0.5 0.2 0.4 -1.1 0.8 1.2 -0.1 0.0
Financial situation satisfaction 0.9 1.1 3.1 -0.8 -0.5 0.7 -1.7 0.8 0.1 1.8 1.1
Tinnitus: Yes, now most or all of the time 1.2 1.4 5.1 -0.1 1.8 2.3 -0.2 1.3 0.6 -0.7 -0.3
Commuting to job workplace: Public transport 0.1 0.2 0.5 0.1 0.6 -0.5 0.0 0.3 -0.3 -0.7 -0.0
Eye problems/disorders: Glaucoma 0.7 0.8 2.8 -0.9 1.7 0.1 -0.9 0.9 0.3 1.1 0.1
Medication: Blood pressure 0.1 0.1 0.6 -0.0 0.8 0.3 -0.1 -0.4 -0.0 -0.3 -0.5
Pain type(s) experienced in last month: Hip pain 0.5 0.6 2.0 -0.5 0.7 -0.3 -0.6 0.7 1.4 0.9 0.7
Supplements: Fish oil (including cod liver oil) 1.8 2.4 5.5 -1.0 1.3 1.9 -1.1 1.8 2.3 -0.3 1.7
High cholesterol (Self-reported) 0.5 1.0 2.1 -1.2 0.5 1.2 -0.7 1.3 -0.4 0.4 1.4
Medication: Bendroflumethiazide 0.7 1.0 1.9 -0.4 1.3 1.4 -1.1 1.2 0.7 0.4 1.2
Medication: Paracetamol 2.1 3.2 5.6 -1.7 1.7 2.4 -2.0 2.4 0.1 1.6 1.2
Medication: Lisinopril 0.3 0.4 1.3 0.4 -1.0 -1.1 0.2 -0.8 -0.1 0.2 -0.4
Medication: Atorvastatin 0.4 0.6 1.9 -0.2 1.4 0.5 0.2 0.7 0.6 0.3 1.1
Illnesses of father: High blood pressure 0.5 0.6 2.2 -0.3 0.3 0.8 -0.7 0.5 -0.0 1.5 1.1
Alcohol drinker status: Never 0.2 0.2 0.9 -0.1 0.4 -0.3 -0.4 -0.4 -0.1 -0.1 1.0
Ever smoked 0.1 0.2 1.3 -0.4 -0.3 -0.1 0.2 -0.0 -0.1 0.3 1.2
Basal metabolic rate 0.4 2.0 6.2 -2.5 -0.2 1.3 -1.8 1.5 0.6 0.9 1.4
Leg fat percentage (left) 1.2 4.3 10.8 -0.7 3.3 1.9 -1.3 2.1 2.8 1.0 2.0
Arm fat-free mass (left) 0.2 1.0 3.3 -1.8 -0.6 1.1 -1.0 0.9 0.2 0.3 1.2
Number of operations (self-reported) 0.7 1.1 1.8 -1.1 0.2 1.2 -1.2 1.0 1.4 1.1 0.5
Average weekly beer plus cider intake 0.3 0.5 2.9 0.4 0.4 -0.4 0.3 -0.4 -1.7 -0.3 -0.4
Irritability 1.6 2.7 4.6 -1.5 2.1 1.9 -1.5 1.7 1.9 1.4 0.4
Risk taking 0.2 0.3 1.6 -0.1 0.1 -0.5 -0.3 0.1 -1.3 -0.3 0.6
Ever had prostate specific antigen (PSA) test 0.5 0.6 2.0 0.5 1.4 0.1 0.7 0.0 -0.5 -0.5 -1.2
Fractured/broken bones in last 5 years 3.6 4.6 8.2 -2.9 2.0 2.4 -2.7 2.5 0.1 2.1 1.0
Age started oral contraceptive pill 0.9 1.2 2.8 0.5 -1.4 -1.7 0.8 -1.5 -0.4 -0.6 -0.9
Diastolic blood pressure, automated reading 0.2 0.5 1.4 0.7 1.2 0.4 0.1 -0.1 1.1 0.2 -0.6
Ever depressed for a whole week 0.4 0.5 1.0 -0.8 1.0 0.4 -0.7 0.6 0.5 1.0 0.1
Unable to work because of sickness or disability 1.0 1.3 3.0 -1.1 0.8 0.2 -1.1 0.8 1.0 1.7 1.6
Commuting to job workplace: Cycle 0.8 0.9 1.9 1.1 -0.8 -0.4 1.2 -1.2 -0.9 -1.4 -0.3
Myopia 0.7 1.0 2.8 0.8 -1.6 0.0 0.5 -0.7 -1.7 -1.2 -0.2
Vascular/heart problems diagnosed by doctor 0.4 1.0 2.0 1.4 -1.4 -0.5 1.2 -0.6 -1.0 -1.0 -0.0
Cholesterol lowering medication 2.8 4.1 6.8 -1.4 2.6 1.9 -1.5 2.5 2.0 1.4 2.5
Medication: Omeprazole (e.g. Zanprol) 1.4 1.7 2.8 -1.6 1.7 1.0 -1.6 1.2 1.5 0.3 -0.6
Pain experienced in last month 0.3 0.5 1.6 0.8 -0.9 -0.4 0.6 -0.3 -0.5 -1.3 -0.6
Supplements: Calcium 0.3 0.3 1.0 -0.5 -1.0 -0.7 0.4 -0.3 -0.0 0.2 0.6
Basal cell carcinoma (self-reported) 0.2 0.2 0.8 0.4 -0.5 0.4 0.4 -0.2 -0.9 -0.5 -0.0
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.2 -0.7 1.1 0.6 -0.1 0.7 0.5 0.2 -0.5
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 2.3 1.5 -0.1 -1.5 1.4 -1.1 -0.7 0.1 -0.1
Heart disease (siblings) 0.0 0.1 0.1 0.0 0.4 0.3 -0.0 -0.0 0.2 -0.4 0.1
Alcohol drinker status: Previous 1.6 1.8 8.0 0.7 -1.3 -1.2 0.8 -1.3 -2.8 -0.3 -0.7
Pack years of smoking 0.9 1.3 5.9 -1.0 0.2 -0.2 -1.1 0.2 2.4 1.2 0.7
Impedance of whole body 0.3 1.3 4.1 2.0 1.9 -0.4 0.9 -0.2 0.9 -0.0 -0.8
Leg fat mass (left) 1.1 4.1 7.0 -1.4 2.3 1.9 -1.7 2.1 2.6 1.3 2.4
Arm predicted mass (left) 0.2 1.1 4.0 -2.0 -0.8 1.0 -1.1 0.9 0.0 0.2 1.1