[Hub]/) : Traits : Blood Red Count :

chr1:153,496,711-156,838,141

Best TWAS P=1.43e-42 · Best GWAS P=7.66e-25 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GBAP1 0.04 0.03 blup 337 0.03 8.6e-05 -4.22 -6.9 4.9e-12 0.81 0.15 0.83 TRUE
2 CommonMind Brain Pre-frontal Cortex THBS3 0.12 0.01 enet 23 0.07 5.6e-09 -10.25 12.2 4.3e-34 -0.58 0.01 0.98 FALSE
3 GTEx Adipose Subcutaneous GBAP1 0.10 0.10 lasso 3 0.08 6.1e-07 -9.51 -9.8 7.5e-23 0.97 0.00 1.00 FALSE
4 GTEx Adipose Subcutaneous GBA 0.08 0.03 lasso 3 0.02 8.9e-03 -9.51 -8.6 5.4e-18 0.94 0.02 0.92 FALSE
5 GTEx Adipose Visceral Omentum GBAP1 0.07 0.11 enet 5 0.10 5.0e-06 -10.29 -10.0 1.7e-23 0.99 0.00 0.99 FALSE
6 GTEx Artery Aorta GBAP1 0.31 0.36 enet 22 0.39 1.0e-22 -10.29 -10.2 2.5e-24 0.94 0.00 1.00 FALSE
7 GTEx Artery Coronary MTX1 0.24 -0.01 lasso 10 0.00 3.3e-01 -2.48 -7.9 3.3e-15 -0.03 0.06 0.22 FALSE
8 GTEx Artery Tibial GBAP1 0.21 0.26 lasso 7 0.26 1.3e-20 -10.29 -9.5 2.0e-21 0.97 0.00 1.00 FALSE
9 GTEx Brain Cerebellar Hemisphere THBS3 0.19 0.26 lasso 2 0.24 8.6e-07 -10.25 10.3 9.0e-25 -0.99 0.00 0.99 FALSE
10 GTEx Brain Cerebellar Hemisphere EFNA1 0.33 0.04 enet 7 0.08 4.5e-03 -8.99 -8.8 9.3e-19 0.90 0.02 0.67 FALSE
11 GTEx Brain Cerebellum MSTO1 0.15 0.06 enet 13 0.07 4.0e-03 8.57 6.5 1.1e-10 -0.80 0.07 0.76 FALSE
12 GTEx Brain Cerebellum THBS3 0.17 0.15 enet 6 0.16 2.0e-05 -10.25 9.2 4.4e-20 -0.90 0.01 0.98 FALSE
13 GTEx Brain Cerebellum EFNA1 0.20 0.09 enet 13 0.06 9.2e-03 8.56 -9.0 2.0e-19 0.90 0.02 0.96 FALSE
14 GTEx Brain Cortex GBAP1 0.25 0.14 enet 25 0.23 4.7e-07 -9.51 8.3 1.3e-16 -0.88 0.02 0.98 FALSE
15 GTEx Brain Frontal Cortex BA9 MTX1P1 0.20 0.05 enet 21 0.01 1.5e-01 7.35 7.5 6.4e-14 -0.73 0.04 0.56 FALSE
16 GTEx Breast Mammary Tissue GBAP1 0.15 0.17 lasso 2 0.15 5.2e-08 -10.29 -10.3 7.3e-25 1.00 0.00 1.00 FALSE
17 GTEx Breast Mammary Tissue SEMA4A 0.20 0.17 lasso 3 0.16 9.4e-09 5.39 5.2 1.9e-07 -0.19 0.02 0.98 FALSE
18 GTEx Breast Mammary Tissue (Male) GBAP1 0.28 0.11 enet 18 0.08 7.3e-03 -10.25 -7.6 3.1e-14 0.77 0.01 0.84 FALSE
19 GTEx Breast Mammary Tissue (Female) GBAP1 0.12 0.02 enet 6 0.02 1.0e-01 -4.22 -5.9 4.7e-09 0.71 0.04 0.52 FALSE
20 GTEx Breast Mammary Tissue (Female) FAM189B 0.05 -0.01 lasso 2 0.00 4.8e-01 8.52 -8.6 1.2e-17 0.66 0.03 0.25 FALSE
21 GTEx Cells EBV-transformed lymphocytes GBAP1 0.21 0.05 lasso 3 0.06 4.5e-03 -9.51 -6.3 2.2e-10 0.86 0.02 0.97 FALSE
22 GTEx Cells Transformed fibroblasts GBAP1 0.18 0.16 lasso 6 0.15 1.6e-11 -10.29 -9.2 3.9e-20 0.99 0.00 1.00 FALSE
23 GTEx Cells Transformed fibroblasts SLC50A1 0.08 0.07 lasso 6 0.07 3.9e-06 8.56 8.4 4.5e-17 -0.76 0.37 0.61 FALSE
24 GTEx Colon Sigmoid GBAP1 0.16 0.13 enet 8 0.14 8.4e-06 -10.29 -10.7 6.9e-27 0.97 0.01 0.99 FALSE
25 GTEx Colon Transverse GBAP1 0.13 0.15 lasso 5 0.11 6.4e-06 -10.29 -9.7 4.7e-22 0.99 0.00 1.00 FALSE
26 GTEx Colon Transverse THBS3 0.11 0.09 lasso 4 0.09 5.9e-05 -10.29 9.3 1.5e-20 -0.95 0.01 0.99 FALSE
27 GTEx Colon Transverse GBA 0.06 0.09 enet 8 0.08 7.9e-05 2.54 -6.5 8.0e-11 0.87 0.01 0.98 FALSE
28 GTEx Colon Transverse RP11-263K19.4 0.14 0.09 enet 10 0.10 1.2e-05 -10.25 6.5 1.0e-10 -0.73 0.01 0.98 FALSE
29 GTEx Esophagus Gastroesophageal Junction GBAP1 0.22 0.19 enet 6 0.17 6.8e-07 -9.51 -9.7 3.4e-22 0.97 0.01 0.99 FALSE
30 GTEx Esophagus Mucosa ADAM15 0.11 0.02 enet 16 0.04 1.5e-03 8.58 6.5 9.1e-11 0.13 0.58 0.03 TRUE
31 GTEx Esophagus Mucosa GBAP1 0.12 0.12 enet 22 0.09 1.7e-06 -10.29 -8.0 1.1e-15 0.93 0.00 1.00 FALSE
32 GTEx Esophagus Mucosa THBS3 0.15 0.15 lasso 2 0.13 6.8e-09 -10.29 10.3 7.0e-25 -1.00 0.00 1.00 FALSE
33 GTEx Esophagus Mucosa MUC1 0.17 0.20 lasso 4 0.18 5.6e-12 9.75 10.1 9.0e-24 -0.81 0.29 0.71 FALSE
34 GTEx Esophagus Mucosa SEMA4A 0.37 0.30 lasso 4 0.33 1.1e-22 4.97 5.2 2.1e-07 -0.20 0.03 0.97 FALSE
35 GTEx Esophagus Mucosa RP11-263K19.4 0.14 0.14 lasso 4 0.12 1.5e-08 -10.29 10.3 8.4e-25 -1.00 0.00 1.00 FALSE
36 GTEx Esophagus Muscularis GBAP1 0.09 0.13 enet 4 0.12 8.9e-08 -8.99 -9.9 5.1e-23 0.99 0.00 1.00 FALSE
37 GTEx Heart Left Ventricle GBAP1 0.18 0.22 enet 13 0.18 1.1e-09 -8.99 -8.1 4.2e-16 0.94 0.02 0.98 FALSE
38 GTEx Lung GBAP1 0.16 0.16 lasso 5 0.15 1.6e-11 -8.99 -9.3 2.0e-20 0.96 0.02 0.98 FALSE
39 GTEx Lung THBS3 0.11 0.07 lasso 4 0.04 1.0e-03 -10.29 10.1 4.6e-24 -0.99 0.00 1.00 FALSE
40 GTEx Nerve Tibial GBAP1 0.12 0.14 lasso 1 0.14 8.9e-10 -10.29 -10.3 7.9e-25 1.00 0.00 1.00 FALSE
41 GTEx Nerve Tibial GBA 0.14 0.02 lasso 5 0.01 3.3e-02 -10.29 -8.5 1.4e-17 0.96 0.01 0.98 FALSE
42 GTEx Pancreas GBAP1 0.12 0.17 enet 10 0.14 2.4e-06 -8.99 -8.5 1.8e-17 0.92 0.01 0.99 FALSE
43 GTEx Pancreas THBS3 0.36 0.14 lasso 6 0.12 1.0e-05 -10.25 10.3 4.5e-25 -0.90 0.01 0.98 FALSE
44 GTEx Pancreas GBA 0.12 0.05 enet 10 0.02 4.2e-02 -10.29 -8.1 4.4e-16 0.90 0.02 0.95 FALSE
45 GTEx Pancreas RP11-263K19.4 0.22 0.06 enet 23 0.05 3.1e-03 -10.25 10.8 2.2e-27 -0.68 0.02 0.78 FALSE
46 GTEx Prostate GBAP1 0.47 0.30 lasso 7 0.32 1.1e-08 -10.29 -10.2 1.3e-24 0.96 0.01 0.99 FALSE
47 GTEx Skin Not Sun Exposed Suprapubic GBAP1 0.15 0.06 lasso 4 0.06 3.6e-04 9.82 -10.6 1.9e-26 0.91 0.01 0.98 TRUE
48 GTEx Skin Not Sun Exposed Suprapubic SEMA4A 0.34 0.31 lasso 2 0.34 3.9e-19 5.37 5.3 1.3e-07 -0.19 0.02 0.98 TRUE
49 GTEx Skin Sun Exposed Lower leg ADAM15 0.14 0.09 lasso 4 0.08 6.1e-07 -4.93 5.5 4.4e-08 -0.09 0.96 0.00 FALSE
50 GTEx Skin Sun Exposed Lower leg SEMA4A 0.51 0.36 enet 3 0.39 3.7e-34 5.39 5.3 1.3e-07 -0.19 0.02 0.98 FALSE
51 GTEx Skin Sun Exposed Lower leg RP11-263K19.4 0.04 0.01 enet 9 0.01 3.3e-02 -10.29 9.2 2.4e-20 -0.98 0.01 0.97 FALSE
52 GTEx Small Intestine Terminal Ileum GBAP1 0.20 0.13 lasso 10 0.11 1.8e-03 8.57 -10.1 4.4e-24 0.93 0.02 0.89 FALSE
53 GTEx Spleen SHC1 0.22 0.14 lasso 2 0.08 4.0e-03 6.46 6.4 1.4e-10 -0.61 0.06 0.61 TRUE
54 GTEx Spleen GBAP1 0.33 0.23 enet 20 0.28 7.9e-08 -9.51 -8.1 4.8e-16 0.87 0.01 0.98 FALSE
55 GTEx Spleen THBS3 0.23 0.10 enet 17 0.08 4.6e-03 6.46 9.5 1.9e-21 -0.80 0.03 0.86 FALSE
56 GTEx Stomach GBAP1 0.09 0.12 lasso 3 0.13 1.2e-06 -8.99 -6.6 3.8e-11 0.88 0.08 0.92 FALSE
57 GTEx Testis THBS3 0.11 0.11 lasso 2 0.09 1.2e-04 -8.99 9.3 1.3e-20 -0.96 0.01 0.99 FALSE
58 GTEx Testis MUC1 0.20 0.02 lasso 7 0.07 7.5e-04 9.82 8.3 8.5e-17 -0.58 0.03 0.91 FALSE
59 GTEx Testis RP11-263K19.4 0.08 0.12 lasso 2 0.10 2.4e-05 -8.99 9.1 9.0e-20 -0.95 0.01 0.98 FALSE
60 GTEx Thyroid FLAD1 0.14 0.09 lasso 7 0.07 9.1e-06 -9.82 -10.4 2.4e-25 0.09 0.19 0.78 TRUE
61 GTEx Thyroid GBAP1 0.23 0.28 lasso 10 0.27 4.6e-21 -10.25 -9.9 2.8e-23 0.99 0.00 1.00 FALSE
62 GTEx Thyroid THBS3 0.12 0.09 enet 8 0.09 3.6e-07 -9.51 7.8 9.3e-15 -0.87 0.01 0.99 FALSE
63 GTEx Thyroid MUC1 0.11 0.02 enet 15 0.09 1.5e-07 -1.48 -6.3 2.9e-10 0.62 0.29 0.71 FALSE
64 GTEx Thyroid SEMA4A 0.48 0.31 lasso 5 0.30 5.8e-23 5.39 5.6 2.3e-08 -0.20 0.02 0.98 FALSE
65 GTEx Vagina GBAP1 0.27 0.08 lasso 7 0.17 1.3e-04 6.46 -7.6 2.2e-14 0.86 0.03 0.89 FALSE
66 GTEx Whole Blood SHC1 0.15 0.08 lasso 4 0.05 8.3e-06 -10.13 -10.3 7.3e-25 -0.01 0.03 0.97 TRUE
67 GTEx Whole Blood THBS3 0.17 0.20 enet 5 0.21 1.0e-18 -10.29 10.1 8.0e-24 -0.99 0.00 1.00 FALSE
68 GTEx Whole Blood SEMA4A 0.10 0.13 enet 3 0.13 3.7e-12 5.37 5.3 1.1e-07 -0.19 0.02 0.98 FALSE
69 GTEx Whole Blood RP11-263K19.4 0.15 0.17 lasso 4 0.17 9.5e-16 -10.29 10.0 2.1e-23 -0.99 0.00 1.00 FALSE
70 METSIM Adipose DCST2 0.04 0.04 enet 12 0.04 4.3e-07 5.88 -6.0 2.7e-09 0.12 0.90 0.06 FALSE
71 METSIM Adipose SEMA4A 0.18 0.13 bslmm 363 0.13 1.8e-18 5.39 5.2 2.0e-07 -0.22 0.02 0.98 FALSE
72 METSIM Adipose THBS3 0.09 0.10 lasso 7 0.12 4.7e-17 -10.29 7.4 1.4e-13 -0.92 0.00 1.00 FALSE
73 NTR Blood THBS3 0.03 0.02 blup 341 0.02 2.8e-08 -10.25 7.7 1.6e-14 -0.77 0.01 0.99 FALSE
74 ROSMAP Brain Pre-frontal Cortex SLC50A1 0.06 0.02 bslmm 331 0.03 4.3e-05 9.75 10.3 1.2e-24 -0.52 0.06 0.90 FALSE
75 YFS Blood MTX1 0.06 0.02 blup 331 0.03 1.9e-10 -10.29 12.0 4.8e-33 -0.66 0.00 1.00 TRUE
76 YFS Blood THBS3 0.29 0.22 enet 38 0.31 6.4e-105 -10.29 13.0 2.0e-38 -0.85 0.00 1.00 FALSE
77 YFS Blood UBAP2L 0.28 0.14 bslmm 364 0.17 2.3e-53 5.41 -6.0 2.5e-09 0.00 0.00 1.00 TRUE
78 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM46 0.03 0.00 blup 33 0.02 3.6e-03 9.75 10.9 1.0e-27 -0.85 0.02 0.47 TRUE
79 The Cancer Genome Atlas Breast Invasive Carcinoma GBA 0.03 0.00 blup 26 0.02 3.1e-04 1.68 -6.3 3.0e-10 0.80 0.01 0.87 FALSE
80 The Cancer Genome Atlas Breast Invasive Carcinoma GBAP1 0.02 0.03 lasso 4 0.03 1.3e-07 -10.29 -7.8 4.3e-15 0.91 0.00 1.00 FALSE
81 The Cancer Genome Atlas Breast Invasive Carcinoma LENEP 0.01 0.00 blup 37 0.01 1.6e-03 0.54 -7.6 3.5e-14 0.00 0.01 0.53 FALSE
82 The Cancer Genome Atlas Breast Invasive Carcinoma THBS3 0.02 0.02 blup 26 0.02 4.0e-05 -10.25 11.7 2.0e-31 -0.93 0.00 0.99 FALSE
83 The Cancer Genome Atlas Breast Invasive Carcinoma TRIM46 0.03 0.01 blup 32 0.01 4.9e-03 9.64 13.7 1.4e-42 -0.61 0.01 0.40 TRUE
84 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma GBAP1 0.10 0.06 enet 9 0.04 5.1e-03 -10.29 -8.0 1.4e-15 0.89 0.00 0.84 FALSE
85 The Cancer Genome Atlas Esophageal Carcinoma FAM189B 0.36 0.05 lasso 3 0.02 6.1e-02 -10.29 -10.1 4.6e-24 1.00 0.00 0.67 FALSE
86 The Cancer Genome Atlas Glioblastoma Multiforme PBXIP1 0.12 0.01 blup 31 0.05 1.5e-02 -2.43 8.1 3.8e-16 0.03 0.02 0.31 TRUE
87 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DCST2 0.04 0.01 blup 50 0.03 2.0e-04 0.67 6.2 5.3e-10 -0.03 0.05 0.80 FALSE
88 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MUC1 0.04 0.01 enet 4 0.02 1.3e-03 9.75 12.8 2.4e-37 -0.78 0.01 0.78 FALSE
89 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma THBS3 0.04 0.01 blup 25 0.03 3.1e-04 7.15 8.1 4.1e-16 -0.80 0.02 0.80 FALSE
90 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GBAP1 0.04 0.04 blup 26 0.04 2.5e-05 8.56 -7.2 8.3e-13 0.85 0.06 0.89 FALSE
91 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma THBS3 0.02 0.03 lasso 4 0.03 2.1e-04 -10.29 10.4 2.4e-25 -0.99 0.00 0.99 FALSE
92 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma THBS3 0.04 0.02 enet 8 0.01 4.5e-02 8.56 5.8 8.0e-09 -0.74 0.02 0.43 FALSE
93 The Cancer Genome Atlas Brain Lower Grade Glioma GBAP1 0.03 0.01 blup 26 0.02 1.9e-03 8.56 -10.7 1.1e-26 0.91 0.02 0.91 FALSE
94 The Cancer Genome Atlas Brain Lower Grade Glioma RAG1AP1 0.07 0.05 blup 77 0.05 3.8e-06 7.90 8.3 7.9e-17 -0.82 0.33 0.66 FALSE
95 The Cancer Genome Atlas Lung Adenocarcinoma GBAP1 0.02 0.03 enet 2 0.02 2.3e-03 -10.29 -10.3 7.3e-25 1.00 0.00 0.95 FALSE
96 The Cancer Genome Atlas Lung Squamous Cell Carcinoma GBAP1 0.04 0.02 blup 27 0.03 4.7e-04 -10.29 -8.1 7.7e-16 0.86 0.00 0.93 FALSE
97 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GBAP1 0.05 0.04 blup 26 0.04 1.6e-03 -10.29 -10.1 8.2e-24 0.91 0.00 0.94 TRUE
98 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TRIM46 0.08 0.08 lasso 2 0.07 2.1e-05 -10.29 10.3 7.9e-25 -1.00 0.00 0.99 FALSE
99 The Cancer Genome Atlas Prostate Adenocarcinoma GBAP1 0.06 0.06 lasso 9 0.06 3.5e-07 8.56 -7.2 5.0e-13 0.80 0.18 0.82 FALSE
100 The Cancer Genome Atlas Prostate Adenocarcinoma SEMA4A 0.11 0.08 blup 51 0.08 7.1e-09 5.39 5.7 1.5e-08 -0.28 0.00 1.00 FALSE
101 The Cancer Genome Atlas Prostate Adenocarcinoma THBS3 0.10 0.12 enet 11 0.10 4.4e-11 -10.25 11.8 2.4e-32 -0.98 0.00 1.00 FALSE
102 The Cancer Genome Atlas Rectum Adenocarcinoma UBQLN4 0.25 0.06 blup 33 0.14 3.6e-04 5.80 -5.2 1.8e-07 0.10 0.00 0.68 TRUE
103 The Cancer Genome Atlas Thyroid Carcinoma GBAP1 0.02 0.01 blup 24 0.02 3.0e-03 -10.29 -8.4 5.8e-17 0.88 0.01 0.79 FALSE
104 The Cancer Genome Atlas Thyroid Carcinoma THBS3 0.14 0.03 enet 16 0.08 3.8e-08 -10.25 9.8 1.8e-22 -0.72 0.00 0.99 FALSE