Hub : Genes

UBAP2L

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 YFS Blood 0.2753 0.0376 0.0000 0.135 0.144 0.163 0.17 0.163 9.9e-42 1.2e-44 5.4e-51 2.3e-53 5.4e-51
2 TCGA Lung Adenocarcinoma 0.0548 0.0289 0.0021 0.004 0.007 0.011 NA 0.000 9.7e-02 4.0e-02 1.6e-02 NA 3.6e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 2.9 4.6 9.3 3.0 0.1
Bipolar Disorder or Schizophrenia 4.4 10.6 18.4 4.3 1.7
Depressed Affect (Nagel 2018) 0.4 0.9 1.3 0.8 -1.1
Depression (Nagel 2018) 0.6 0.9 1.0 -1.0 0.9
Intelligence (Savage-Jansen 2018) 2.4 7.4 14.0 3.7 -1.0
Neuroticism (Nagel 2018) 1.1 2.5 4.7 2.2 -0.6
Schizophrenia (2018) 3.4 7.0 9.4 3.1 2.1
Schizophrenia vs Biploar Disorder 3.3 4.4 7.6 -1.1 2.8
Worry (Nagel 2018) 0.3 0.6 1.3 1.1 0.0
Alzheimer’s Disease (in mother) 0.6 0.7 1.1 -0.4 1.1
Alzheimer’s Disease (in father) 2.6 2.8 4.3 -2.1 1.2
Alzheimer’s Disease (including proxy) 0.7 1.0 1.1 -1.1 1.0
Crohns Disease (2017) 5.0 11.0 21.5 -0.7 -4.6
Irritable Bowel Disease (IBD) 1.0 2.4 4.5 -0.6 -2.1
Ulcerative Colitis (UC) 0.1 0.2 0.2 -0.4 0.5
Major Depression (MDD) 5.7 6.9 13.5 -0.6 3.7
Reaction Time 0.7 1.3 2.5 1.6 0.2
Verbal and Numeric Reasoning (VNR) 0.3 0.8 1.6 1.3 -0.1
Breast Cancer 0.8 2.0 2.2 1.5 -1.4
Ovarian Cancer 0.5 0.6 0.9 0.6 0.9
Prostate Cancer 0.7 0.9 1.1 1.1 -0.9
Age at First Birth 4.7 6.9 12.8 1.0 -3.6
Bipolar Disorder (2011) 0.5 0.4 0.8 -0.2 -0.9
Body Mass Index (BMI) (2010) 0.0 0.0 0.0 -0.2 0.1
Coronary Artery Disease (CAD) 0.3 0.3 0.6 0.8 0.1
Crohns Disease (2012) 2.2 3.5 7.0 -0.3 -2.6
Mean Putamen Volume 1.1 1.2 2.2 -0.5 1.5
Fasting Glucose 0.1 0.1 0.1 -0.3 0.3
HbA1C 0.0 0.1 0.1 0.3 -0.1
HDL Cholesterol 1.6 2.8 3.9 2.0 -1.3
LDL Cholesterol 0.6 1.0 1.9 0.2 1.4
Lupus 0.0 0.1 0.1 0.2 -0.3
Neuroticism (2016) 0.3 0.4 0.6 0.5 0.8
Primary Biliary Cirrhosis 0.6 0.8 1.0 1.0 -0.8
Rheumatoid Arthritis 2.3 3.2 5.1 -2.3 -1.1
Schizophrenia (2014) 3.6 8.0 15.6 3.9 0.7
Triglycerides 2.1 3.4 4.1 -1.6 2.0
Type 2 Diabetes (T2D) (2012) 1.0 1.2 2.1 -1.4 -0.6
Ulcerative Colitis 0.2 0.3 0.5 -0.7 0.5
Blood Eosinophil Count 0.5 3.7 7.2 -0.3 2.7
Blood Platelet Count 0.2 1.9 3.4 1.9 -0.7
Blood Red Count 2.0 19.1 35.5 -6.0 1.6
Blood White Count 0.3 2.5 4.9 -2.2 0.3
Heel T-Score 0.1 0.7 1.0 1.0 -0.7
BMI 0.0 0.0 0.0 -0.2 0.2
Height 0.3 5.8 11.2 0.6 3.4
Waist Hip Ratio (WHR) 0.2 1.1 2.2 -1.5 -0.0
Systolic Blood Pressure 0.4 1.9 2.7 1.6 -1.1
Smoking Status 11.6 27.8 38.1 -6.2 4.2
Allergy or Eczema 2.8 7.4 11.8 1.7 3.4
Cardiovascular Disease 0.8 2.6 5.0 -2.2 -0.4
Hypothyroidism (self reported) 2.8 6.4 12.8 -3.6 -0.2
Respiratory disease 1.2 2.7 3.3 1.8 1.4
Type 2 Diabetes (T2D) (2018) 0.5 1.0 1.6 -0.6 -1.2
Lung FEV1/FVC ratio 1.2 6.0 7.9 2.8 -2.0
Lung FVC 1.5 7.9 15.5 -3.9 -0.5
Neuroticism 1.1 2.6 3.1 1.5 -1.8
Chronotype (morning person) 1.6 3.7 5.8 2.4 1.3
Hair Pigment 0.2 5.1 10.0 -3.2 -0.5
Tanning 0.1 1.2 2.4 0.0 1.6
Hand grip strength (left) 1.0 2.5 3.4 -1.3 1.8
Number of treatments/medications taken 0.4 0.8 1.2 -1.1 -0.6
Average weekly spirits intake 0.7 0.9 1.1 -1.0 -0.9
Sensitivity / hurt feelings 0.7 1.3 2.4 1.6 -0.4
Frequency of depressed mood in last 2 weeks 0.1 0.1 0.3 -0.5 0.1
Hearing difficulty/problems: Yes 0.2 0.4 0.7 0.8 0.2
Relative age of first facial hair 0.8 1.6 3.3 -1.8 -0.0
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 1.5 -0.5 -1.2
Ever used hormone-replacement therapy (HRT) 1.0 1.3 2.5 -1.6 -0.2
Ever had hysterectomy (womb removed) 0.3 0.4 0.7 -0.8 0.3
Systolic blood pressure, automated reading 0.8 2.2 2.4 1.6 -1.4
Eye problems/disorders: Diabetes related eye disease 2.2 2.5 3.5 1.2 -1.9
Angina 2.6 3.4 4.8 -1.4 -2.2
Medication for hormone replacement therapy 0.4 0.4 0.5 -0.6 0.7
Vitamin and mineral supplements 1.2 1.6 2.1 -1.1 -1.4
Supplements: Zinc 1.4 1.6 2.2 1.5 0.9
Medication: Co-codamol 0.9 1.0 1.3 0.8 1.2
Medication: Metformin 0.6 0.8 1.4 0.5 -1.2
Diabetes (father) 0.8 0.9 1.6 1.3 -0.5
Diabetes (mother) 0.0 0.1 0.1 -0.1 0.3
Severe depression (siblings) 1.2 1.3 1.9 -0.9 1.4
Pack years adult smoking proportion 0.8 1.2 2.0 -1.4 0.7
Impedance of leg (right) 0.5 2.3 3.8 -1.9 0.9
Leg fat-free mass (left) 0.2 1.0 1.7 1.3 0.5
Trunk fat percentage 0.0 0.1 0.1 -0.3 -0.3
Hand grip strength (right) 0.6 1.8 2.6 -1.6 1.0
Townsend deprivation index at recruitment 1.4 1.9 3.5 -0.6 1.9
Current tobacco smoking 3.6 5.9 10.4 -3.2 1.2
Average weekly fortified wine intake 2.2 2.6 3.5 1.9 -1.3
Maternal smoking around birth 2.7 3.9 4.7 -2.2 1.8
Fed-up feelings 0.3 0.6 0.6 -0.8 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.5 0.7 -0.8 0.5
Relative age voice broke 0.1 0.1 0.2 -0.1 0.4
Taking other prescription medications 0.3 0.5 0.5 -0.7 -0.7
Age when periods started (menarche) 1.3 3.2 3.7 -1.7 -1.9
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 2.8 -1.7 0.0
Heel bone mineral density (BMD) T-score, automated (left) 0.0 0.1 0.1 -0.4 0.0
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 1.8 -0.8 1.3
Qualifications: CSEs or equivalent 0.1 0.1 0.1 0.3 0.2
Serious illness, injury or assault to yourself 0.4 0.4 0.9 0.9 0.0
High blood pressure 0.2 0.6 0.8 -0.9 -0.7
Hayfever, allergic rhinitis or eczema 3.7 8.0 15.5 0.7 3.9
Multivitamins +/- minerals 2.3 2.9 5.1 2.3 0.9
Stomach or abdominal pain in last month 0.3 0.4 0.7 -0.2 0.8
Supplements: Glucosamine 0.2 0.2 0.3 0.6 0.3
Diverticular disease/diverticulitis (self-reported) 1.5 1.7 1.8 -1.4 1.3
Medication: Atenolol 0.8 1.0 1.1 -0.9 -1.1
Medication: Levothyroxine sodium 3.0 5.2 9.5 -3.1 -0.9
Sitting height 0.3 2.2 4.0 -0.6 2.0
Chronic bronchitis/emphysema (father) 0.5 0.6 0.7 -0.7 0.8
High blood pressure (mother) 0.7 0.9 1.3 1.1 0.7
Body mass index (BMI) 0.1 0.3 0.7 0.1 -0.8
Impedance of leg (left) 0.9 4.6 6.5 -2.5 1.6
Leg predicted mass (left) 0.2 0.9 1.6 1.3 0.4
Trunk fat mass 0.0 0.1 0.1 -0.4 -0.0
Waist circumference 0.0 0.1 0.2 -0.5 0.2
Number of incorrect matches in round 0.3 0.4 0.6 0.8 0.5
Past tobacco smoking 6.9 12.7 14.3 3.8 -3.3
Alcohol usually taken with meals 1.2 1.9 3.8 1.9 0.2
Nervous feelings 0.1 0.1 0.2 -0.4 0.0
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 0.2 -0.4 0.5
Hearing difficulty/problems with background noise 0.2 0.4 0.5 -0.5 0.7
Hair/balding pattern: Pattern 2 1.7 2.2 4.1 0.5 2.0
Had menopause 0.8 1.0 1.1 -0.9 -1.1
Had other major operations 1.3 1.6 1.6 -1.3 1.2
Forced vital capacity (FVC) 1.5 5.8 10.0 -3.2 1.3
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 0.7 -0.8 0.3
Ever unenthusiastic/disinterested for a whole week 2.0 2.4 4.5 -0.6 2.1
Qualifications: None of the above 0.6 1.2 2.3 -1.5 0.2
Financial difficulties in last 2 years 0.2 0.2 0.4 -0.2 0.6
Mouth/teeth dental problems 1.0 1.6 2.9 0.6 1.7
Heart attack 0.5 0.6 0.7 0.8 -0.8
Allergy 2.8 6.6 8.8 -2.1 -3.0
Pain all over the body in last month 0.7 0.8 1.5 0.2 -1.2
Diabetes (self-reported) 1.2 1.9 3.8 0.1 -2.0
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 1.9 0.7 1.4
Medication: Ramipril 0.3 0.4 0.8 -0.9 0.0
Medication: Simvastatin 0.8 1.1 1.8 -1.3 -0.7
Fluid intelligence score 0.0 0.0 0.0 0.2 0.2
Illnesses of siblings 0.1 0.1 0.1 0.2 0.4
Neuroticism score 1.0 2.2 2.2 1.5 -1.5
Weight 0.0 0.1 0.2 -0.1 0.5
Impedance of arm (right) 0.2 0.8 1.3 1.1 0.6
Arm fat percentage (right) 0.2 0.6 1.0 0.5 -1.0
Trunk fat-free mass 0.0 0.3 0.5 -0.0 0.7
Hip circumference 0.0 0.2 0.4 -0.1 0.6
Time employed in main current job 1.1 1.2 1.7 -1.3 -0.9
Alcohol intake versus 10 years previously 0.3 0.4 0.7 0.8 -0.4
Father’s age at death 0.1 0.1 0.2 0.1 -0.4
Worrier / anxious feelings 1.0 1.8 3.4 0.5 -1.8
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.1 2.6 -1.2 1.6
Falls in the last year 2.1 2.8 3.3 1.8 -1.5
Hair/balding pattern: Pattern 3 1.6 2.3 4.6 -0.1 -2.1
Number of live births 2.9 4.1 7.3 -0.9 2.7
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 2.6 -1.6 0.5
Pulse rate 0.4 0.6 1.2 0.2 -1.1
Happiness 0.2 0.3 0.3 -0.4 -0.6
Noisy workplace 1.3 1.6 3.1 1.8 0.3
Qualifications: A levels/AS levels or equivalent 0.8 1.8 3.4 1.8 0.4
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 2.7 0.1 -1.6
Mouth/teeth dental problems: Dentures 0.6 1.0 1.5 -0.7 -1.2
Asthma 1.0 1.9 2.2 1.5 1.3
Medication: Ibuprofen (e.g. Nurofen) 2.3 2.9 4.1 2.0 1.3
Medication: Cholesterol lowering 3.0 4.6 6.9 -2.6 -1.5
Depression (self-reported) 0.2 0.2 0.3 0.6 -0.4
Medication: Lansoprazole 0.9 1.0 2.1 -1.4 0.1
Prospective memory result 1.1 1.3 2.6 1.6 -0.0
Lung cancer (father) 0.1 0.1 0.2 -0.4 0.0
Illnesses of mother 0.8 1.0 2.0 0.1 -1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.6 3.5 -1.9 1.3
Pulse wave Arterial Stiffness index 0.2 0.2 0.4 0.1 -0.7
Impedance of arm (left) 0.2 0.9 1.6 1.2 0.4
Arm fat mass (right) 0.0 0.0 0.1 -0.1 -0.2
Trunk predicted mass 0.0 0.3 0.5 0.0 0.7
Standing height 0.5 4.6 9.1 -0.2 3.0
Length of working week for main job 0.2 0.2 0.4 0.2 0.6
Exposure to tobacco smoke at home 2.7 3.1 3.1 -1.8 1.7
Breastfed as a baby 0.9 1.1 2.2 1.5 -0.1
Tense / ‘highly strung’ 0.4 0.6 1.2 1.1 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.7 1.4 1.2 0.2
Hair/balding pattern: Pattern 4 1.4 3.4 6.8 -0.1 -2.6
Birth weight of first child 0.1 0.2 0.4 -0.6 0.1
Peak expiratory flow (PEF) 0.2 0.4 0.5 -0.5 0.7
Pulse wave reflection index 0.1 0.1 0.1 -0.2 0.3
Ever highly irritable/argumentative for 2 days 0.7 0.8 1.0 0.8 1.0
Loud music exposure frequency 0.9 0.9 1.6 -0.5 1.3
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.1 0.3 -0.3
Mouth/teeth dental problems: Bleeding gums 1.0 1.4 2.0 -0.9 -1.4
Blood clot in the leg (DVT) 1.0 1.3 2.6 1.6 0.1
Medication: Paracetamol 1.3 2.1 3.1 1.0 1.8
Headache pain in last month 1.5 2.5 5.0 -0.3 2.2
Medication for cholesterol, blood pressure or diabetes 3.9 6.4 8.9 2.0 3.0
Glaucoma (self-reported) 0.0 0.0 0.1 0.0 0.3
Gout (self-reported) 0.6 0.9 0.9 1.0 0.9
Hypothyroidism/myxoedema (self-reported) 2.9 5.6 10.8 -3.3 -0.7
Medication: Amlodipine 0.2 0.3 0.4 -0.7 0.3
Medication: Ventolin 100micrograms inhaler 2.9 3.7 7.2 0.4 2.7
Birth weight 0.4 0.9 1.0 1.0 -0.9
Chronic bronchitis/emphysema (mother) 1.4 1.6 2.0 1.4 1.1
High blood pressure (siblings) 0.1 0.1 0.1 0.3 0.4
Forced vital capacity (FVC), Best measure 1.6 5.7 8.9 -3.0 1.6
Body fat percentage 0.1 0.5 0.5 -0.7 -0.7
Leg fat percentage (right) 0.3 1.2 1.3 -1.2 -1.0
Arm fat-free mass (right) 0.1 0.4 0.8 -0.9 0.4
Exposure to tobacco smoke outside home 1.2 1.6 2.2 1.0 1.5
Comparative body size at age 10 1.3 3.7 7.3 0.1 -2.7
Number of full brothers 1.7 2.2 2.4 1.4 1.5
Worry too long after embarrassment 0.6 1.1 1.4 1.2 -0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 1.5 -0.7 1.2
Wheeze or whistling in the chest in last year 2.2 3.9 5.7 2.4 1.4
Number of children fathered 0.0 0.1 0.1 0.2 0.3
Reason for reducing amount of alcohol drunk: Health precaution 1.1 1.3 1.3 1.1 1.2
Age at first live birth 3.7 6.6 7.2 2.7 -2.4
Pulse wave peak to peak time 0.4 0.4 0.9 -0.2 0.9
Health satisfaction 0.5 0.6 1.2 -0.1 1.1
Shortness of breath walking on level ground 0.2 0.2 0.2 0.4 0.4
Qualifications: College or University degree 2.3 7.3 14.7 3.8 0.1
Eye problems/disorders: None of the above 0.8 0.9 1.6 -0.5 1.2
Mouth/teeth dental problems: Loose teeth 0.3 0.4 0.6 -0.8 -0.5
Emphysema/chronic bronchitis 1.6 1.8 2.7 1.6 -0.9
Medication for pain relief, constipation, heartburn 0.8 1.4 2.3 -0.6 -1.5
Neck or shoulder pain in last month 0.8 1.2 1.9 0.7 1.4
Medication: Blood pressure 1.9 3.3 6.3 -0.6 -2.5
Angina (self-reported) 2.3 3.0 3.5 -1.6 -1.9
Migraine (self-reported) 6.2 7.7 13.1 -3.6 1.5
Medication: Ibuprofen 2.6 3.1 3.6 1.9 1.6
Medication: Allopurinol 0.5 0.6 0.7 0.8 0.7
Medication: Omeprazole 0.0 0.1 0.1 0.3 0.2
Medication: Seretide 50 evohaler 0.9 1.0 1.7 0.5 -1.3
Mean time to correctly identify matches 0.1 0.2 0.4 0.6 -0.3
Heart disease (mother) 0.4 0.5 0.9 -0.1 0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 7.8 9.3 15.4 -1.8 3.9
Whole body fat mass 0.0 0.2 0.3 -0.5 -0.2
Leg fat mass (right) 0.0 0.1 0.2 -0.4 -0.3
Arm predicted mass (right) 0.1 0.6 0.8 -0.9 0.6
Pulse rate, automated reading 0.1 0.2 0.4 0.1 -0.6
Alcohol intake frequency. 0.5 1.1 1.6 0.7 1.3
Comparative height size at age 10 2.0 11.0 20.1 -1.4 4.5
Number of full sisters 0.4 0.5 0.9 0.3 1.0
Suffer from ‘nerves’ 0.2 0.3 0.3 -0.5 0.5
Overall health rating 1.3 2.7 4.2 -2.0 1.1
Chest pain or discomfort 0.3 0.5 1.0 1.0 -0.1
Had major operations 0.1 0.1 0.2 -0.1 0.4
Age at last live birth 1.8 2.6 4.6 2.1 -0.8
Family relationship satisfaction 0.4 0.5 0.8 0.9 -0.4
Leg pain on walking 0.1 0.1 0.1 -0.4 0.4
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.4 -0.7 0.2
Commuting to job workplace: Car/motor vehicle 0.7 0.9 1.6 1.3 -0.2
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 1.6 -0.1 -1.3
Medication: Aspirin 0.4 0.5 1.0 -1.0 -0.1
Supplements: Vitamin C 0.1 0.1 0.1 0.3 0.3
Knee pain experienced in last month 1.8 2.8 5.3 2.3 -0.5
Hypertension (Self-reported) 0.2 0.5 0.5 -0.7 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.0 0.0 0.0 0.2 -0.1
Illnesses of father: Heart disease 4.9 6.8 10.9 1.6 -3.3
Illnesses of siblings: Diabetes 0.3 0.3 0.6 -0.7 -0.4
Smoking status: Previous 6.2 9.3 9.7 -3.1 3.0
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 1.3 0.2 1.1
Whole body fat-free mass 0.0 0.3 0.4 0.3 0.6
Leg fat-free mass (right) 0.2 1.0 1.3 1.1 0.9
Arm fat percentage (left) 0.2 0.9 1.5 0.5 -1.2
Average weekly red wine intake 2.5 3.7 7.1 2.7 -0.6
Handedness (chirality/laterality): Left-handed 0.1 0.2 0.2 0.5 -0.3
Mood swings 1.2 2.1 2.2 1.4 -1.5
Loneliness, isolation 0.7 1.0 1.8 1.4 0.4
Long-standing illness, disability or infirmity 0.6 0.9 1.9 0.1 -1.4
Ever had bowel cancer screening 0.1 0.1 0.2 0.4 -0.3
Diabetes diagnosed by doctor 0.2 0.3 0.6 -0.2 -0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.3 -0.1 -0.6
Friendships satisfaction 1.2 1.5 2.3 0.9 -1.5
Qualifications: nursing, teaching 0.1 0.2 0.3 0.6 0.0
Commuting to job workplace: Walk 2.0 2.1 4.2 -2.0 0.2
Eye problems/disorders: Cataract 1.7 2.0 4.0 0.2 -2.0
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 0.6 0.0 -0.8
Medication for cholesterol 0.6 0.9 1.5 1.2 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.0 0.1 0.1 -0.3 -0.0
Back pain experienced in last month 0.5 0.7 1.1 -0.5 1.0
Mineral and other dietary supplements 0.8 1.1 2.0 -1.4 -0.4
Breast cancer (self-reported) 1.1 1.3 1.9 -0.8 1.4
Asthma (self-reported) 1.2 2.3 2.4 1.6 1.5
Osteoporosis (self-reported) 3.6 4.4 5.3 -2.3 -1.9
Osteoarthritis (self-reported) 0.8 1.0 2.0 0.2 1.4
Medication: Aspirin 0.1 0.2 0.4 -0.6 -0.1
Medication: Gliclazide 0.4 0.4 0.7 -0.9 0.4
Illnesses of father: None of the above (group 1) 1.8 2.2 2.9 -1.2 1.7
Smoking status: Current 3.2 5.1 8.9 -3.0 1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.6 4.0 -2.0 -1.1
Whole body water mass 0.0 0.2 0.4 0.2 0.6
Leg predicted mass (right) 0.2 1.0 1.5 1.2 0.8
Arm fat mass (left) 0.0 0.2 0.3 0.2 -0.6
Number of self-reported non-cancer illnesses 0.5 0.9 1.2 -0.8 1.1
Average weekly champagne plus white wine intake 0.3 0.4 0.7 -0.8 0.3
Miserableness 1.0 1.6 3.0 0.6 -1.7
Guilty feelings 0.7 1.0 1.1 1.0 1.0
Wears glasses or contact lenses 0.0 0.0 0.0 -0.1 0.1
Ever taken oral contraceptive pill 1.4 1.5 2.2 0.9 -1.5
Hearing aid user 1.8 2.1 4.1 -2.0 0.2
Mother’s age at death 0.3 0.4 0.7 -0.2 -0.8
Financial situation satisfaction 0.1 0.1 0.2 0.1 0.4
Tinnitus: Yes, now most or all of the time 2.3 2.6 5.1 -2.2 0.5
Commuting to job workplace: Public transport 0.6 0.7 1.3 -1.2 0.1
Eye problems/disorders: Glaucoma 0.3 0.3 0.4 0.5 0.7
Medication: Blood pressure 0.7 1.4 1.7 -1.3 1.0
Pain type(s) experienced in last month: Hip pain 1.4 1.7 2.9 0.8 1.7
Supplements: Fish oil (including cod liver oil) 1.3 1.7 3.3 -0.0 1.8
High cholesterol (Self-reported) 1.7 3.0 5.9 -2.4 -0.2
Medication: Bendroflumethiazide 1.6 2.5 4.9 -0.0 -2.2
Medication: Paracetamol 1.7 2.6 4.5 0.8 2.1
Medication: Lisinopril 0.0 0.0 0.1 -0.1 -0.3
Medication: Atorvastatin 0.8 1.0 2.0 -0.0 -1.4
Illnesses of father: High blood pressure 1.1 1.4 1.4 1.1 1.2
Alcohol drinker status: Never 5.1 6.2 8.1 -2.1 2.8
Ever smoked 5.0 8.8 9.2 -3.0 2.9
Basal metabolic rate 0.1 0.4 0.7 0.2 0.8
Leg fat percentage (left) 0.3 1.2 2.1 -1.4 -0.6
Arm fat-free mass (left) 0.2 0.8 1.2 -1.1 0.7
Number of operations (self-reported) 1.3 1.9 3.6 -1.9 0.3
Average weekly beer plus cider intake 0.2 0.3 0.3 0.6 0.5
Irritability 1.8 3.0 4.0 2.0 -1.4
Risk taking 1.5 2.2 3.6 1.9 0.9
Ever had prostate specific antigen (PSA) test 1.2 1.4 1.8 1.3 1.0
Fractured/broken bones in last 5 years 1.1 1.4 2.5 0.5 -1.6
Age started oral contraceptive pill 2.9 3.7 7.2 0.3 -2.7
Diastolic blood pressure, automated reading 0.5 1.5 2.8 -1.7 -0.3
Ever depressed for a whole week 0.3 0.3 0.5 -0.3 0.7
Unable to work because of sickness or disability 0.4 0.5 0.9 -1.0 0.2
Commuting to job workplace: Cycle 0.8 1.0 1.2 0.9 -1.1
Myopia 0.2 0.2 0.4 -0.2 0.7
Vascular/heart problems diagnosed by doctor 0.4 1.2 1.3 1.1 1.1
Cholesterol lowering medication 0.9 1.3 1.5 -1.2 1.0
Medication: Omeprazole (e.g. Zanprol) 0.2 0.2 0.4 -0.6 -0.1
Pain experienced in last month 0.7 1.2 1.9 -0.8 -1.4
Supplements: Calcium 4.0 4.5 5.6 1.8 -2.4
Basal cell carcinoma (self-reported) 0.9 1.0 1.8 -1.4 0.5
Heart attack/myocardial infarction (self-reported) 0.3 0.4 0.6 0.5 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 1.6 1.3 -0.2
Heart disease (siblings) 0.2 0.3 0.4 0.5 -0.6
Alcohol drinker status: Previous 1.0 1.1 1.3 -1.1 0.9
Pack years of smoking 1.0 1.5 2.3 -1.5 0.8
Impedance of whole body 0.2 1.0 1.4 -0.7 1.2
Leg fat mass (left) 0.0 0.2 0.4 -0.6 -0.1
Arm predicted mass (left) 0.1 0.6 0.7 -0.8 0.7