TWAS hub - UBAP2L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.2753	0.0376	0.0000	0.135	0.144	0.163	0.17	0.163	9.9e-42	1.2e-44	5.4e-51	2.3e-53	5.4e-51
2	TCGA	Lung Adenocarcinoma	0.0548	0.0289	0.0021	0.004	0.007	0.011	NA	0.000	9.7e-02	4.0e-02	1.6e-02	NA	3.6e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Smoking Status	11.6	27.8	38.1	-6.2	4.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	7.8	9.3	15.4	-1.8	3.9
Past tobacco smoking	6.9	12.7	14.3	3.8	-3.3
Migraine (self-reported)	6.2	7.7	13.1	-3.6	1.5
Smoking status: Previous	6.2	9.3	9.7	-3.1	3.0
Major Depression (MDD)	5.7	6.9	13.5	-0.6	3.7
Alcohol drinker status: Never	5.1	6.2	8.1	-2.1	2.8
Crohns Disease (2017)	5.0	11.0	21.5	-0.7	-4.6
Ever smoked	5.0	8.8	9.2	-3.0	2.9
Illnesses of father: Heart disease	4.9	6.8	10.9	1.6	-3.3
Age at First Birth	4.7	6.9	12.8	1.0	-3.6
Bipolar Disorder or Schizophrenia	4.4	10.6	18.4	4.3	1.7
Supplements: Calcium	4.0	4.5	5.6	1.8	-2.4
Medication for cholesterol, blood pressure or diabetes	3.9	6.4	8.9	2.0	3.0
Hayfever, allergic rhinitis or eczema	3.7	8.0	15.5	0.7	3.9
Age at first live birth	3.7	6.6	7.2	2.7	-2.4
Schizophrenia (2014)	3.6	8.0	15.6	3.9	0.7
Current tobacco smoking	3.6	5.9	10.4	-3.2	1.2
Osteoporosis (self-reported)	3.6	4.4	5.3	-2.3	-1.9
Schizophrenia (2018)	3.4	7.0	9.4	3.1	2.1
Schizophrenia vs Biploar Disorder	3.3	4.4	7.6	-1.1	2.8
Smoking status: Current	3.2	5.1	8.9	-3.0	1.1
Medication: Levothyroxine sodium	3.0	5.2	9.5	-3.1	-0.9
Medication: Cholesterol lowering	3.0	4.6	6.9	-2.6	-1.5
Bipolar Disorder (2018)	2.9	4.6	9.3	3.0	0.1
Number of live births	2.9	4.1	7.3	-0.9	2.7
Hypothyroidism/myxoedema (self-reported)	2.9	5.6	10.8	-3.3	-0.7
Medication: Ventolin 100micrograms inhaler	2.9	3.7	7.2	0.4	2.7
Age started oral contraceptive pill	2.9	3.7	7.2	0.3	-2.7
Allergy or Eczema	2.8	7.4	11.8	1.7	3.4
Hypothyroidism (self reported)	2.8	6.4	12.8	-3.6	-0.2
Allergy	2.8	6.6	8.8	-2.1	-3.0
Maternal smoking around birth	2.7	3.9	4.7	-2.2	1.8
Exposure to tobacco smoke at home	2.7	3.1	3.1	-1.8	1.7
Alzheimer’s Disease (in father)	2.6	2.8	4.3	-2.1	1.2
Angina	2.6	3.4	4.8	-1.4	-2.2
Medication: Ibuprofen	2.6	3.1	3.6	1.9	1.6
Average weekly red wine intake	2.5	3.7	7.1	2.7	-0.6
Intelligence (Savage-Jansen 2018)	2.4	7.4	14.0	3.7	-1.0
Rheumatoid Arthritis	2.3	3.2	5.1	-2.3	-1.1
Multivitamins +/- minerals	2.3	2.9	5.1	2.3	0.9
Medication: Ibuprofen (e.g. Nurofen)	2.3	2.9	4.1	2.0	1.3
Qualifications: College or University degree	2.3	7.3	14.7	3.8	0.1
Angina (self-reported)	2.3	3.0	3.5	-1.6	-1.9
Tinnitus: Yes, now most or all of the time	2.3	2.6	5.1	-2.2	0.5
Crohns Disease (2012)	2.2	3.5	7.0	-0.3	-2.6
Eye problems/disorders: Diabetes related eye disease	2.2	2.5	3.5	1.2	-1.9
Average weekly fortified wine intake	2.2	2.6	3.5	1.9	-1.3
Wheeze or whistling in the chest in last year	2.2	3.9	5.7	2.4	1.4
Triglycerides	2.1	3.4	4.1	-1.6	2.0
Falls in the last year	2.1	2.8	3.3	1.8	-1.5
Blood Red Count	2.0	19.1	35.5	-6.0	1.6
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	4.5	-0.6	2.1
Comparative height size at age 10	2.0	11.0	20.1	-1.4	4.5
Commuting to job workplace: Walk	2.0	2.1	4.2	-2.0	0.2
Medication: Blood pressure	1.9	3.3	6.3	-0.6	-2.5
Age at last live birth	1.8	2.6	4.6	2.1	-0.8
Knee pain experienced in last month	1.8	2.8	5.3	2.3	-0.5
Illnesses of father: None of the above (group 1)	1.8	2.2	2.9	-1.2	1.7
Hearing aid user	1.8	2.1	4.1	-2.0	0.2
Irritability	1.8	3.0	4.0	2.0	-1.4
Hair/balding pattern: Pattern 2	1.7	2.2	4.1	0.5	2.0
Number of full brothers	1.7	2.2	2.4	1.4	1.5
Eye problems/disorders: Cataract	1.7	2.0	4.0	0.2	-2.0
High cholesterol (Self-reported)	1.7	3.0	5.9	-2.4	-0.2
Medication: Paracetamol	1.7	2.6	4.5	0.8	2.1
HDL Cholesterol	1.6	2.8	3.9	2.0	-1.3
Chronotype (morning person)	1.6	3.7	5.8	2.4	1.3
Hair/balding pattern: Pattern 3	1.6	2.3	4.6	-0.1	-2.1
Forced vital capacity (FVC), Best measure	1.6	5.7	8.9	-3.0	1.6
Emphysema/chronic bronchitis	1.6	1.8	2.7	1.6	-0.9
Medication: Bendroflumethiazide	1.6	2.5	4.9	-0.0	-2.2
Lung FVC	1.5	7.9	15.5	-3.9	-0.5
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	1.8	-1.4	1.3
Forced vital capacity (FVC)	1.5	5.8	10.0	-3.2	1.3
Headache pain in last month	1.5	2.5	5.0	-0.3	2.2
Risk taking	1.5	2.2	3.6	1.9	0.9
Supplements: Zinc	1.4	1.6	2.2	1.5	0.9
Townsend deprivation index at recruitment	1.4	1.9	3.5	-0.6	1.9
Hair/balding pattern: Pattern 4	1.4	3.4	6.8	-0.1	-2.6
Chronic bronchitis/emphysema (mother)	1.4	1.6	2.0	1.4	1.1
Ever taken oral contraceptive pill	1.4	1.5	2.2	0.9	-1.5
Pain type(s) experienced in last month: Hip pain	1.4	1.7	2.9	0.8	1.7
Age when periods started (menarche)	1.3	3.2	3.7	-1.7	-1.9
Had other major operations	1.3	1.6	1.6	-1.3	1.2
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	2.6	-1.2	1.6
Noisy workplace	1.3	1.6	3.1	1.8	0.3
Medication: Paracetamol	1.3	2.1	3.1	1.0	1.8
Comparative body size at age 10	1.3	3.7	7.3	0.1	-2.7
Overall health rating	1.3	2.7	4.2	-2.0	1.1
Supplements: Fish oil (including cod liver oil)	1.3	1.7	3.3	-0.0	1.8
Number of operations (self-reported)	1.3	1.9	3.6	-1.9	0.3
Respiratory disease	1.2	2.7	3.3	1.8	1.4
Lung FEV1/FVC ratio	1.2	6.0	7.9	2.8	-2.0
Vitamin and mineral supplements	1.2	1.6	2.1	-1.1	-1.4
Severe depression (siblings)	1.2	1.3	1.9	-0.9	1.4
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.8	-1.7	0.0
Alcohol usually taken with meals	1.2	1.9	3.8	1.9	0.2
Diabetes (self-reported)	1.2	1.9	3.8	0.1	-2.0
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.7	0.1	-1.6
Exposure to tobacco smoke outside home	1.2	1.6	2.2	1.0	1.5
Mood swings	1.2	2.1	2.2	1.4	-1.5
Friendships satisfaction	1.2	1.5	2.3	0.9	-1.5
Asthma (self-reported)	1.2	2.3	2.4	1.6	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	4.0	-2.0	-1.1
Ever had prostate specific antigen (PSA) test	1.2	1.4	1.8	1.3	1.0
Neuroticism (Nagel 2018)	1.1	2.5	4.7	2.2	-0.6
Mean Putamen Volume	1.1	1.2	2.2	-0.5	1.5
Neuroticism	1.1	2.6	3.1	1.5	-1.8
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	1.8	-0.8	1.3
Time employed in main current job	1.1	1.2	1.7	-1.3	-0.9
Prospective memory result	1.1	1.3	2.6	1.6	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	1.3	1.1	1.2
Breast cancer (self-reported)	1.1	1.3	1.9	-0.8	1.4
Illnesses of father: High blood pressure	1.1	1.4	1.4	1.1	1.2
Fractured/broken bones in last 5 years	1.1	1.4	2.5	0.5	-1.6
Irritable Bowel Disease (IBD)	1.0	2.4	4.5	-0.6	-2.1
Type 2 Diabetes (T2D) (2012)	1.0	1.2	2.1	-1.4	-0.6
Hand grip strength (left)	1.0	2.5	3.4	-1.3	1.8
Ever used hormone-replacement therapy (HRT)	1.0	1.3	2.5	-1.6	-0.2
Mouth/teeth dental problems	1.0	1.6	2.9	0.6	1.7
Neuroticism score	1.0	2.2	2.2	1.5	-1.5
Worrier / anxious feelings	1.0	1.8	3.4	0.5	-1.8
Asthma	1.0	1.9	2.2	1.5	1.3
Mouth/teeth dental problems: Bleeding gums	1.0	1.4	2.0	-0.9	-1.4
Blood clot in the leg (DVT)	1.0	1.3	2.6	1.6	0.1
Miserableness	1.0	1.6	3.0	0.6	-1.7
Alcohol drinker status: Previous	1.0	1.1	1.3	-1.1	0.9
Pack years of smoking	1.0	1.5	2.3	-1.5	0.8
Medication: Co-codamol	0.9	1.0	1.3	0.8	1.2
Impedance of leg (left)	0.9	4.6	6.5	-2.5	1.6
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	1.9	0.7	1.4
Medication: Lansoprazole	0.9	1.0	2.1	-1.4	0.1
Breastfed as a baby	0.9	1.1	2.2	1.5	-0.1
Loud music exposure frequency	0.9	0.9	1.6	-0.5	1.3
Medication: Seretide 50 evohaler	0.9	1.0	1.7	0.5	-1.3
Cholesterol lowering medication	0.9	1.3	1.5	-1.2	1.0
Basal cell carcinoma (self-reported)	0.9	1.0	1.8	-1.4	0.5
Breast Cancer	0.8	2.0	2.2	1.5	-1.4
Cardiovascular Disease	0.8	2.6	5.0	-2.2	-0.4
Relative age of first facial hair	0.8	1.6	3.3	-1.8	-0.0
Systolic blood pressure, automated reading	0.8	2.2	2.4	1.6	-1.4
Diabetes (father)	0.8	0.9	1.6	1.3	-0.5
Pack years adult smoking proportion	0.8	1.2	2.0	-1.4	0.7
Medication: Atenolol	0.8	1.0	1.1	-0.9	-1.1
Had menopause	0.8	1.0	1.1	-0.9	-1.1
Medication: Simvastatin	0.8	1.1	1.8	-1.3	-0.7
Qualifications: A levels/AS levels or equivalent	0.8	1.8	3.4	1.8	0.4
Illnesses of mother	0.8	1.0	2.0	0.1	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	3.5	-1.9	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	1.5	-0.7	1.2
Eye problems/disorders: None of the above	0.8	0.9	1.6	-0.5	1.2
Medication for pain relief, constipation, heartburn	0.8	1.4	2.3	-0.6	-1.5
Neck or shoulder pain in last month	0.8	1.2	1.9	0.7	1.4
Mineral and other dietary supplements	0.8	1.1	2.0	-1.4	-0.4
Osteoarthritis (self-reported)	0.8	1.0	2.0	0.2	1.4
Medication: Atorvastatin	0.8	1.0	2.0	-0.0	-1.4
Commuting to job workplace: Cycle	0.8	1.0	1.2	0.9	-1.1
Alzheimer’s Disease (including proxy)	0.7	1.0	1.1	-1.1	1.0
Reaction Time	0.7	1.3	2.5	1.6	0.2
Prostate Cancer	0.7	0.9	1.1	1.1	-0.9
Average weekly spirits intake	0.7	0.9	1.1	-1.0	-0.9
Sensitivity / hurt feelings	0.7	1.3	2.4	1.6	-0.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.5	-0.5	-1.2
High blood pressure (mother)	0.7	0.9	1.3	1.1	0.7
Pain all over the body in last month	0.7	0.8	1.5	0.2	-1.2
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.0	0.8	1.0
Commuting to job workplace: Car/motor vehicle	0.7	0.9	1.6	1.3	-0.2
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.6	-0.1	-1.3
Loneliness, isolation	0.7	1.0	1.8	1.4	0.4
Guilty feelings	0.7	1.0	1.1	1.0	1.0
Medication: Blood pressure	0.7	1.4	1.7	-1.3	1.0
Pain experienced in last month	0.7	1.2	1.9	-0.8	-1.4
Depression (Nagel 2018)	0.6	0.9	1.0	-1.0	0.9
Alzheimer’s Disease (in mother)	0.6	0.7	1.1	-0.4	1.1
LDL Cholesterol	0.6	1.0	1.9	0.2	1.4
Primary Biliary Cirrhosis	0.6	0.8	1.0	1.0	-0.8
Medication: Metformin	0.6	0.8	1.4	0.5	-1.2
Hand grip strength (right)	0.6	1.8	2.6	-1.6	1.0
Qualifications: None of the above	0.6	1.2	2.3	-1.5	0.2
Mouth/teeth dental problems: Dentures	0.6	1.0	1.5	-0.7	-1.2
Gout (self-reported)	0.6	0.9	0.9	1.0	0.9
Worry too long after embarrassment	0.6	1.1	1.4	1.2	-0.9
Long-standing illness, disability or infirmity	0.6	0.9	1.9	0.1	-1.4
Medication for cholesterol	0.6	0.9	1.5	1.2	-0.5
Commuting to job workplace: Public transport	0.6	0.7	1.3	-1.2	0.1
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.6	1.3	-0.2
Ovarian Cancer	0.5	0.6	0.9	0.6	0.9
Bipolar Disorder (2011)	0.5	0.4	0.8	-0.2	-0.9
Blood Eosinophil Count	0.5	3.7	7.2	-0.3	2.7
Type 2 Diabetes (T2D) (2018)	0.5	1.0	1.6	-0.6	-1.2
Impedance of leg (right)	0.5	2.3	3.8	-1.9	0.9
Chronic bronchitis/emphysema (father)	0.5	0.6	0.7	-0.7	0.8
Heart attack	0.5	0.6	0.7	0.8	-0.8
Standing height	0.5	4.6	9.1	-0.2	3.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.4	1.2	0.2
Health satisfaction	0.5	0.6	1.2	-0.1	1.1
Medication: Allopurinol	0.5	0.6	0.7	0.8	0.7
Alcohol intake frequency.	0.5	1.1	1.6	0.7	1.3
Back pain experienced in last month	0.5	0.7	1.1	-0.5	1.0
Number of self-reported non-cancer illnesses	0.5	0.9	1.2	-0.8	1.1
Diastolic blood pressure, automated reading	0.5	1.5	2.8	-1.7	-0.3
Depressed Affect (Nagel 2018)	0.4	0.9	1.3	0.8	-1.1
Systolic Blood Pressure	0.4	1.9	2.7	1.6	-1.1
Number of treatments/medications taken	0.4	0.8	1.2	-1.1	-0.6
Medication for hormone replacement therapy	0.4	0.4	0.5	-0.6	0.7
Serious illness, injury or assault to yourself	0.4	0.4	0.9	0.9	0.0
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	2.6	-1.6	0.5
Pulse rate	0.4	0.6	1.2	0.2	-1.1
Tense / ‘highly strung’	0.4	0.6	1.2	1.1	0.2
Birth weight	0.4	0.9	1.0	1.0	-0.9
Pulse wave peak to peak time	0.4	0.4	0.9	-0.2	0.9
Heart disease (mother)	0.4	0.5	0.9	-0.1	0.9
Number of full sisters	0.4	0.5	0.9	0.3	1.0
Family relationship satisfaction	0.4	0.5	0.8	0.9	-0.4
Medication: Aspirin	0.4	0.5	1.0	-1.0	-0.1
Medication: Gliclazide	0.4	0.4	0.7	-0.9	0.4
Unable to work because of sickness or disability	0.4	0.5	0.9	-1.0	0.2
Vascular/heart problems diagnosed by doctor	0.4	1.2	1.3	1.1	1.1
Worry (Nagel 2018)	0.3	0.6	1.3	1.1	0.0
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.6	1.3	-0.1
Coronary Artery Disease (CAD)	0.3	0.3	0.6	0.8	0.1
Neuroticism (2016)	0.3	0.4	0.6	0.5	0.8
Blood White Count	0.3	2.5	4.9	-2.2	0.3
Height	0.3	5.8	11.2	0.6	3.4
Ever had hysterectomy (womb removed)	0.3	0.4	0.7	-0.8	0.3
Fed-up feelings	0.3	0.6	0.6	-0.8	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	0.7	-0.8	0.5
Taking other prescription medications	0.3	0.5	0.5	-0.7	-0.7
Stomach or abdominal pain in last month	0.3	0.4	0.7	-0.2	0.8
Sitting height	0.3	2.2	4.0	-0.6	2.0
Number of incorrect matches in round	0.3	0.4	0.6	0.8	0.5
Medication: Ramipril	0.3	0.4	0.8	-0.9	0.0
Alcohol intake versus 10 years previously	0.3	0.4	0.7	0.8	-0.4
Leg fat percentage (right)	0.3	1.2	1.3	-1.2	-1.0
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.6	-0.8	-0.5
Chest pain or discomfort	0.3	0.5	1.0	1.0	-0.1
Illnesses of siblings: Diabetes	0.3	0.3	0.6	-0.7	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	1.3	0.2	1.1
Average weekly champagne plus white wine intake	0.3	0.4	0.7	-0.8	0.3
Mother’s age at death	0.3	0.4	0.7	-0.2	-0.8
Eye problems/disorders: Glaucoma	0.3	0.3	0.4	0.5	0.7
Leg fat percentage (left)	0.3	1.2	2.1	-1.4	-0.6
Ever depressed for a whole week	0.3	0.3	0.5	-0.3	0.7
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.6	0.5	-0.8
Ulcerative Colitis	0.2	0.3	0.5	-0.7	0.5
Blood Platelet Count	0.2	1.9	3.4	1.9	-0.7
Waist Hip Ratio (WHR)	0.2	1.1	2.2	-1.5	-0.0
Hair Pigment	0.2	5.1	10.0	-3.2	-0.5
Hearing difficulty/problems: Yes	0.2	0.4	0.7	0.8	0.2
Leg fat-free mass (left)	0.2	1.0	1.7	1.3	0.5
High blood pressure	0.2	0.6	0.8	-0.9	-0.7
Supplements: Glucosamine	0.2	0.2	0.3	0.6	0.3
Leg predicted mass (left)	0.2	0.9	1.6	1.3	0.4
Hearing difficulty/problems with background noise	0.2	0.4	0.5	-0.5	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.7	-0.8	0.3
Financial difficulties in last 2 years	0.2	0.2	0.4	-0.2	0.6
Impedance of arm (right)	0.2	0.8	1.3	1.1	0.6
Arm fat percentage (right)	0.2	0.6	1.0	0.5	-1.0
Happiness	0.2	0.3	0.3	-0.4	-0.6
Depression (self-reported)	0.2	0.2	0.3	0.6	-0.4
Pulse wave Arterial Stiffness index	0.2	0.2	0.4	0.1	-0.7
Impedance of arm (left)	0.2	0.9	1.6	1.2	0.4
Length of working week for main job	0.2	0.2	0.4	0.2	0.6
Peak expiratory flow (PEF)	0.2	0.4	0.5	-0.5	0.7
Medication: Amlodipine	0.2	0.3	0.4	-0.7	0.3
Shortness of breath walking on level ground	0.2	0.2	0.2	0.4	0.4
Suffer from ‘nerves’	0.2	0.3	0.3	-0.5	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	-0.7	0.2
Hypertension (Self-reported)	0.2	0.5	0.5	-0.7	-0.6
Leg fat-free mass (right)	0.2	1.0	1.3	1.1	0.9
Arm fat percentage (left)	0.2	0.9	1.5	0.5	-1.2
Diabetes diagnosed by doctor	0.2	0.3	0.6	-0.2	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.3	-0.1	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.6	0.0	-0.8
Leg predicted mass (right)	0.2	1.0	1.5	1.2	0.8
Arm fat-free mass (left)	0.2	0.8	1.2	-1.1	0.7
Average weekly beer plus cider intake	0.2	0.3	0.3	0.6	0.5
Myopia	0.2	0.2	0.4	-0.2	0.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.4	-0.6	-0.1
Heart disease (siblings)	0.2	0.3	0.4	0.5	-0.6
Impedance of whole body	0.2	1.0	1.4	-0.7	1.2
Ulcerative Colitis (UC)	0.1	0.2	0.2	-0.4	0.5
Fasting Glucose	0.1	0.1	0.1	-0.3	0.3
Heel T-Score	0.1	0.7	1.0	1.0	-0.7
Tanning	0.1	1.2	2.4	0.0	1.6
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.3	-0.5	0.1
Relative age voice broke	0.1	0.1	0.2	-0.1	0.4
Qualifications: CSEs or equivalent	0.1	0.1	0.1	0.3	0.2
Body mass index (BMI)	0.1	0.3	0.7	0.1	-0.8
Nervous feelings	0.1	0.1	0.2	-0.4	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.2	-0.4	0.5
Illnesses of siblings	0.1	0.1	0.1	0.2	0.4
Father’s age at death	0.1	0.1	0.2	0.1	-0.4
Lung cancer (father)	0.1	0.1	0.2	-0.4	0.0
Birth weight of first child	0.1	0.2	0.4	-0.6	0.1
Pulse wave reflection index	0.1	0.1	0.1	-0.2	0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.1	0.3	-0.3
High blood pressure (siblings)	0.1	0.1	0.1	0.3	0.4
Body fat percentage	0.1	0.5	0.5	-0.7	-0.7
Arm fat-free mass (right)	0.1	0.4	0.8	-0.9	0.4
Mean time to correctly identify matches	0.1	0.2	0.4	0.6	-0.3
Arm predicted mass (right)	0.1	0.6	0.8	-0.9	0.6
Pulse rate, automated reading	0.1	0.2	0.4	0.1	-0.6
Had major operations	0.1	0.1	0.2	-0.1	0.4
Leg pain on walking	0.1	0.1	0.1	-0.4	0.4
Supplements: Vitamin C	0.1	0.1	0.1	0.3	0.3
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.2	0.5	-0.3
Ever had bowel cancer screening	0.1	0.1	0.2	0.4	-0.3
Qualifications: nursing, teaching	0.1	0.2	0.3	0.6	0.0
Medication: Aspirin	0.1	0.2	0.4	-0.6	-0.1
Financial situation satisfaction	0.1	0.1	0.2	0.1	0.4
Basal metabolic rate	0.1	0.4	0.7	0.2	0.8
Arm predicted mass (left)	0.1	0.6	0.7	-0.8	0.7
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	-0.2	0.1
HbA1C	0.0	0.1	0.1	0.3	-0.1
Lupus	0.0	0.1	0.1	0.2	-0.3
BMI	0.0	0.0	0.0	-0.2	0.2
Diabetes (mother)	0.0	0.1	0.1	-0.1	0.3
Trunk fat percentage	0.0	0.1	0.1	-0.3	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.1	-0.4	0.0
Trunk fat mass	0.0	0.1	0.1	-0.4	-0.0
Waist circumference	0.0	0.1	0.2	-0.5	0.2
Fluid intelligence score	0.0	0.0	0.0	0.2	0.2
Weight	0.0	0.1	0.2	-0.1	0.5
Trunk fat-free mass	0.0	0.3	0.5	-0.0	0.7
Hip circumference	0.0	0.2	0.4	-0.1	0.6
Arm fat mass (right)	0.0	0.0	0.1	-0.1	-0.2
Trunk predicted mass	0.0	0.3	0.5	0.0	0.7
Glaucoma (self-reported)	0.0	0.0	0.1	0.0	0.3
Number of children fathered	0.0	0.1	0.1	0.2	0.3
Medication: Omeprazole	0.0	0.1	0.1	0.3	0.2
Whole body fat mass	0.0	0.2	0.3	-0.5	-0.2
Leg fat mass (right)	0.0	0.1	0.2	-0.4	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.0	0.2	-0.1
Whole body fat-free mass	0.0	0.3	0.4	0.3	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.1	0.1	-0.3	-0.0
Whole body water mass	0.0	0.2	0.4	0.2	0.6
Arm fat mass (left)	0.0	0.2	0.3	0.2	-0.6
Wears glasses or contact lenses	0.0	0.0	0.0	-0.1	0.1
Medication: Lisinopril	0.0	0.0	0.1	-0.1	-0.3
Leg fat mass (left)	0.0	0.2	0.4	-0.6	-0.1

Hub : Genes

UBAP2L

Models

Trait associations