TWAS hub - PIP5K1A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Caudate basal ganglia	0.3980	0.0970	1.6e-04	0.181	NA	0.059	NA	0.174	7.0e-06	NA	8.8e-03	NA	1.0e-05
2	TCGA	Breast Invasive Carcinoma	0.0388	0.0209	8.1e-09	0.051	0.037	0.045	NA	0.046	1.2e-10	4.3e-08	1.3e-09	NA	8.8e-10
3	TCGA	Colon Adenocarcinoma	0.0520	0.0300	7.6e-04	0.027	0.035	0.024	NA	0.017	1.0e-02	4.0e-03	1.5e-02	NA	3.3e-02
4	TCGA	Esophageal Carcinoma	0.1000	0.0680	8.4e-03	0.061	0.014	0.035	NA	0.040	5.3e-03	1.1e-01	2.8e-02	NA	2.1e-02
5	TCGA	Brain Lower Grade Glioma	0.0171	0.0111	4.9e-03	0.017	0.014	0.009	NA	0.015	4.5e-03	9.3e-03	2.6e-02	NA	6.2e-03
6	TCGA	Lung Adenocarcinoma	0.0307	0.0256	2.6e-03	0.012	0.016	0.011	NA	0.012	1.3e-02	5.1e-03	1.7e-02	NA	1.2e-02
7	TCGA	Stomach Adenocarcinoma	0.0900	0.0560	3.6e-04	0.026	0.043	0.040	NA	0.060	5.1e-03	4.6e-04	6.5e-04	NA	3.7e-05
8	TCGA	Thyroid Carcinoma	0.0360	0.0200	5.5e-05	0.055	0.044	0.038	NA	0.051	4.4e-06	3.8e-05	1.3e-04	NA	9.7e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Qualifications: CSEs or equivalent	10.2	13.4	24.8	-2.8	-3.8	-2.3	-4.1	-3.2	-3.7	-5.0	-3.8
Basal cell carcinoma (self-reported)	7.5	8.9	10.6	-3.2	-2.9	-2.5	-3.0	-2.9	-3.3	-3.2	-2.8
Impedance of arm (right)	7.4	34.4	47.3	-3.9	-6.3	-6.7	-6.0	-6.9	-6.1	-4.1	-6.2
Impedance of arm (left)	5.7	26.5	35.3	-3.9	-5.5	-5.9	-5.0	-5.8	-5.5	-3.8	-5.3
Schizophrenia vs Biploar Disorder	4.9	6.5	7.5	-2.4	-2.5	-2.7	-2.7	-2.7	-2.7	-2.1	-2.5
Reason for reducing amount of alcohol drunk: Health precaution	4.8	5.6	7.6	2.0	2.3	2.8	2.5	2.7	2.5	1.7	2.3
Alzheimer’s Disease (in father)	4.5	4.9	6.8	-2.3	-2.3	-2.6	-2.4	-2.3	-2.1	-1.5	-2.2
Medication: Bendroflumethiazide	4.4	6.7	11.0	3.3	2.6	3.1	2.3	3.1	2.2	0.8	2.4
Pain experienced in last month	4.4	7.4	10.6	-1.4	-3.1	-2.9	-3.0	-3.2	-2.9	-1.1	-3.3
Comparative height size at age 10	4.3	23.9	34.3	-4.5	-5.3	-5.9	-5.4	-5.5	-4.6	-1.2	-5.2
Impedance of whole body	4.1	20.7	25.9	-3.4	-4.8	-4.8	-4.2	-5.0	-5.1	-4.3	-4.6
Blood Platelet Count	4.0	46.8	67.4	5.5	7.0	8.2	6.3	7.6	7.8	4.8	6.8
Breast Cancer	3.8	9.1	13.0	1.9	3.2	3.2	3.2	3.6	3.3	2.0	3.2
Height	3.8	73.1	89.7	-9.5	-9.3	-9.3	-8.9	-8.6	-8.5	-3.7	-9.1
Type 2 Diabetes (T2D) (2012)	3.7	4.3	8.0	2.8	2.1	1.8	2.1	1.7	2.0	1.8	2.0
Allergy or Eczema	3.6	9.4	18.7	-2.2	-2.8	-2.7	-2.4	-2.9	-3.9	-4.3	-2.7
Medication: Atorvastatin	3.6	4.4	7.2	-1.5	-2.4	-1.3	-2.6	-1.4	-1.8	-2.7	-2.5
Falls in the last year	3.4	4.6	5.8	-1.6	-2.3	-1.9	-2.2	-2.2	-2.3	-2.4	-2.2
Standing height	3.4	33.3	45.4	-6.7	-6.3	-6.4	-5.8	-5.6	-5.8	-1.9	-6.1
Heart attack/myocardial infarction (self-reported)	3.4	4.4	5.6	-1.0	-2.2	-1.9	-2.4	-2.2	-2.2	-2.3	-2.2
Depression (self-reported)	3.3	3.9	5.9	-2.4	-2.3	-1.9	-2.4	-1.7	-1.3	-1.2	-2.2
Illnesses of father: None of the above (group 1)	3.3	4.1	6.1	0.8	2.4	2.1	2.4	1.8	2.0	1.8	2.5
Heart attack	3.2	4.1	5.6	-1.1	-2.1	-1.8	-2.3	-2.1	-2.2	-2.4	-2.1
Supplements: Calcium	3.1	3.4	5.4	-1.0	-1.9	-2.0	-1.8	-1.9	-2.3	-1.7	-1.9
Impedance of leg (right)	3.0	14.4	22.7	-2.8	-3.9	-3.1	-3.5	-3.9	-4.3	-4.8	-3.8
Number of incorrect matches in round	3.0	5.0	12.8	2.3	2.0	1.6	2.0	1.4	2.4	3.6	2.0
Illnesses of father: Heart disease	3.0	4.2	6.0	-0.9	-2.4	-2.1	-2.3	-2.3	-2.2	-1.2	-2.4
Eye problems/disorders: Cataract	3.0	3.5	5.7	-2.1	-1.9	-2.4	-1.9	-2.1	-1.6	-0.1	-1.9
Current tobacco smoking	2.9	4.8	6.4	-2.0	-2.1	-2.5	-1.9	-2.5	-2.4	-1.9	-2.0
Forced expiratory volume in 1-second (FEV1), predicted	2.9	6.0	9.9	-3.1	-2.7	-1.8	-2.3	-1.5	-2.4	-2.7	-2.6
Back pain experienced in last month	2.9	4.2	5.2	1.8	2.2	2.2	2.0	2.2	2.3	1.2	2.2
Myopia	2.9	4.2	9.0	1.4	1.9	1.6	2.0	1.9	2.4	3.0	1.9
High blood pressure (siblings)	2.8	4.1	5.7	2.1	2.0	2.4	1.8	2.4	2.0	1.3	1.9
Angina (self-reported)	2.8	3.6	6.0	-0.8	-2.2	-2.3	-2.2	-2.4	-1.5	-0.6	-2.2
Medication: Omeprazole (e.g. Zanprol)	2.8	3.4	4.4	-1.4	-2.1	-1.6	-2.1	-1.8	-1.9	-1.7	-2.1
Vitamin and mineral supplements	2.7	3.7	5.6	0.4	2.1	2.4	2.2	2.2	2.0	1.0	2.1
Intelligence (Savage-Jansen 2018)	2.6	8.0	11.3	-2.6	-2.8	-2.9	-2.6	-2.9	-3.4	-2.6	-2.7
Supplements: Zinc	2.6	2.8	4.3	-2.0	-1.7	-2.1	-1.4	-2.0	-1.6	-0.1	-1.6
Illness, injury, bereavement, stress in last 2 years	2.6	3.2	7.5	0.7	1.9	1.1	2.0	1.3	1.8	2.7	2.0
Impedance of leg (left)	2.5	12.1	21.0	-2.5	-3.5	-2.7	-3.1	-3.6	-4.0	-4.6	-3.4
Qualifications: O levels/GCSEs or equivalent	2.4	3.8	5.9	-1.4	-2.1	-2.4	-2.3	-2.2	-2.0	-0.2	-2.1
Blood Eosinophil Count	2.3	17.8	31.1	2.5	4.8	4.9	5.6	4.3	3.3	2.3	4.8
Average weekly champagne plus white wine intake	2.3	3.2	4.7	1.6	1.8	2.2	1.8	2.2	1.8	0.9	1.7
Ever depressed for a whole week	2.3	2.8	4.7	-0.7	-2.1	-1.2	-2.2	-1.6	-1.4	-1.6	-2.1
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.5	4.4	-1.3	-2.1	-0.7	-1.7	-1.0	-1.2	-1.9	-2.1
Angina	2.1	2.8	4.7	-0.5	-1.9	-2.0	-2.0	-2.2	-1.3	-0.5	-1.9
Commuting to job workplace: Walk	2.1	2.2	3.1	-1.1	-1.7	-1.2	-1.6	-1.4	-1.5	-1.8	-1.6
Hayfever, allergic rhinitis or eczema	2.0	4.3	12.3	-0.9	-1.7	-1.6	-1.5	-1.9	-2.7	-3.5	-1.7
Sitting height	2.0	13.9	18.1	-4.2	-4.0	-4.0	-3.8	-3.5	-4.0	-1.9	-3.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.0	5.1	-0.2	-2.1	-1.6	-2.2	-1.9	-1.7	-1.1	-2.1
Commuting to job workplace: Cycle	2.0	2.4	4.1	2.0	1.3	1.8	1.5	1.7	1.7	1.0	1.2
Trunk fat percentage	1.9	7.5	9.0	-2.4	-2.9	-2.8	-2.8	-2.9	-3.0	-2.2	-2.8
Hand grip strength (right)	1.9	5.1	15.8	-4.0	-1.9	-2.4	-1.9	-1.8	-1.9	-1.1	-1.8
Pain type(s) experienced in last month: Hip pain	1.9	2.4	4.5	-2.1	-1.5	-1.8	-1.4	-1.4	-1.5	-1.1	-1.4
Primary Biliary Cirrhosis	1.8	2.6	4.6	1.3	1.7	1.1	1.8	1.4	1.6	2.1	1.7
Relative age of first facial hair	1.8	3.7	8.8	-1.7	-2.0	-1.3	-1.7	-1.2	-2.0	-3.0	-2.0
Mean Putamen Volume	1.7	1.9	2.4	-0.7	-1.5	-1.2	-1.4	-1.2	-1.6	-1.6	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	4.8	-0.7	-1.4	-0.9	-1.6	-1.8	-1.5	-2.2	-1.4
Medication: Lansoprazole	1.7	1.9	3.3	-1.5	-1.6	-0.3	-1.6	-0.6	-1.2	-1.8	-1.6
Commuting to job workplace: Car/motor vehicle	1.7	1.9	2.9	-0.4	-1.3	-1.6	-1.7	-1.7	-1.5	-1.1	-1.4
Smoking status: Current	1.7	2.7	3.8	-1.6	-1.6	-2.0	-1.3	-1.9	-1.8	-1.3	-1.5
Townsend deprivation index at recruitment	1.6	2.2	3.3	-0.1	-1.5	-1.5	-1.5	-1.8	-1.8	-1.4	-1.5
Average weekly fortified wine intake	1.6	1.8	3.5	-1.3	-1.4	-1.9	-1.2	-1.6	-1.3	-0.3	-1.4
Serious illness, injury or assault to yourself	1.6	1.9	4.7	-0.4	-1.3	-1.1	-1.3	-1.0	-1.7	-2.2	-1.4
Medication: Levothyroxine sodium	1.6	2.8	6.2	2.0	1.6	0.6	1.4	1.2	1.9	2.5	1.6
Qualifications: A levels/AS levels or equivalent	1.6	3.5	5.8	-1.9	-1.8	-2.4	-1.9	-2.2	-2.0	0.2	-1.8
Prospective memory result	1.6	1.9	2.7	1.3	1.5	1.0	1.4	1.3	1.5	1.6	1.4
Hypothyroidism/myxoedema (self-reported)	1.6	3.0	6.8	2.6	1.6	0.7	1.5	1.1	1.8	2.3	1.6
Exposure to tobacco smoke outside home	1.6	2.1	4.2	0.0	-1.3	-1.5	-1.7	-2.0	-1.4	-1.3	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	3.1	-0.8	-1.5	-1.5	-1.8	-1.7	-1.8	-0.5	-1.5
Neck or shoulder pain in last month	1.6	2.3	4.2	1.1	1.4	2.1	1.3	1.9	1.9	0.7	1.4
Mineral and other dietary supplements	1.6	2.2	4.5	1.2	1.5	2.1	1.4	1.4	1.6	0.8	1.4
High cholesterol (Self-reported)	1.6	2.8	4.8	-1.4	-2.0	-1.1	-2.2	-0.9	-1.1	-2.1	-1.9
Cholesterol lowering medication	1.6	2.3	4.6	-0.8	-1.8	-1.5	-2.1	-1.3	-1.1	-1.5	-1.7
Hand grip strength (left)	1.5	4.0	16.6	-4.1	-1.5	-2.2	-1.3	-1.6	-1.7	-0.2	-1.3
Trunk fat mass	1.5	6.3	7.4	-2.5	-2.7	-2.5	-2.6	-2.5	-2.7	-1.7	-2.6
Handedness (chirality/laterality): Left-handed	1.5	1.8	6.2	1.1	1.1	0.6	1.2	0.6	1.4	2.5	1.1
Supplements: Fish oil (including cod liver oil)	1.5	1.9	3.5	-1.9	-1.4	-1.9	-1.1	-1.1	-1.4	-0.7	-1.2
Verbal and Numeric Reasoning (VNR)	1.4	3.5	5.3	-1.8	-1.7	-1.6	-1.7	-1.9	-2.3	-2.1	-1.7
Severe depression (siblings)	1.4	1.5	3.6	0.1	-1.0	-1.9	-1.0	-1.5	-0.6	1.6	-1.0
Hair/balding pattern: Pattern 3	1.4	2.1	3.2	0.4	1.6	1.3	1.8	1.6	1.5	1.3	1.7
Medication: Paracetamol	1.4	2.3	4.3	1.3	1.9	1.4	1.7	1.6	1.1	0.1	2.1
Eye problems/disorders: None of the above	1.4	1.6	3.7	1.1	1.1	1.7	1.2	1.9	1.0	-0.2	1.1
Supplements: Vitamin C	1.4	1.6	3.7	-0.6	-1.3	-1.9	-1.2	-1.6	-1.3	0.2	-1.3
Long-standing illness, disability or infirmity	1.4	2.1	3.1	-0.2	-1.5	-1.5	-1.6	-1.2	-1.7	-1.8	-1.5
Bipolar Disorder (2018)	1.3	2.0	3.6	0.8	1.3	0.8	1.6	1.5	1.7	1.9	1.5
Crohns Disease (2012)	1.3	2.2	4.0	0.8	-1.4	-1.4	-1.9	-2.0	-1.3	-1.0	-1.6
Fasting Glucose	1.3	1.6	5.5	0.5	1.2	-0.3	1.4	0.4	1.4	2.3	1.2
Supplements: Glucosamine	1.3	1.8	4.7	-2.2	-1.3	-1.3	-1.2	-0.7	-1.4	-0.9	-1.1
Fluid intelligence score	1.3	2.6	3.8	-1.8	-1.5	-1.3	-1.5	-1.5	-1.9	-1.8	-1.5
Mood swings	1.3	2.4	5.3	2.3	1.6	1.7	1.4	1.2	1.5	0.7	1.5
Medication: Paracetamol	1.3	2.0	3.8	1.2	1.9	1.4	1.7	1.4	0.9	0.1	1.9
Medication: Lisinopril	1.3	1.6	2.8	0.5	1.2	1.5	1.0	1.5	1.7	1.3	1.2
Lung FVC	1.2	6.1	17.3	0.3	2.3	1.1	2.4	2.1	2.9	4.2	2.5
Illnesses of siblings	1.2	1.7	3.5	-1.9	-1.0	-1.3	-1.0	-1.3	-1.3	-1.5	-1.0
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.3	-1.1	-1.0	-1.1	-1.2	-1.5	-1.2	-1.1	-1.0
Body fat percentage	1.2	4.8	5.9	-1.9	-2.3	-2.0	-2.3	-2.3	-2.4	-2.1	-2.2
Health satisfaction	1.2	1.6	4.1	2.0	1.5	1.0	1.2	1.2	0.8	0.2	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.0	-1.0	-1.4	-1.1	-1.4	-1.0	-1.0	-0.8	-1.4
Ever had prostate specific antigen (PSA) test	1.2	1.4	2.5	0.3	1.4	1.2	1.2	1.1	1.6	0.7	1.5
Blood White Count	1.1	8.3	14.1	1.2	2.6	3.6	2.9	3.2	3.8	2.1	2.7
Hypothyroidism (self reported)	1.1	2.5	8.4	2.9	1.0	0.1	0.7	0.6	1.5	2.6	0.9
Loud music exposure frequency	1.1	1.2	1.4	-1.1	-1.1	-1.1	-1.0	-1.0	-1.0	-1.2	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	5.5	-0.4	-1.0	0.1	-1.1	-0.4	-0.9	-2.3	-1.0
Hearing aid user	1.1	1.2	4.0	-2.0	-0.9	-0.8	-0.7	-0.7	-1.2	-1.2	-0.7
Number of operations (self-reported)	1.1	1.6	2.2	0.5	1.4	1.4	1.3	1.0	1.2	1.3	1.5
Crohns Disease (2017)	1.0	2.2	5.1	1.7	-0.9	-1.4	-1.6	-2.3	-1.0	-1.2	-1.2
Ulcerative Colitis	1.0	1.5	7.1	2.7	0.9	0.5	0.3	0.2	1.1	1.3	0.8
Hearing difficulty/problems: Yes	1.0	1.5	2.5	0.6	1.3	1.3	1.1	1.2	1.6	1.1	1.4
Relative age voice broke	1.0	1.5	6.9	-1.3	-1.0	0.0	-0.8	0.2	-1.1	-2.6	-0.9
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	2.2	-0.5	-0.9	-0.8	-1.1	-1.5	-1.0	-1.5	-0.9
Qualifications: None of the above	1.0	2.2	3.6	0.6	1.6	1.5	1.7	1.1	1.9	1.3	1.7
Medication: Cholesterol lowering	1.0	1.5	2.5	-0.9	-1.5	-0.6	-1.6	-0.8	-1.0	-1.6	-1.4
Birth weight of first child	1.0	1.8	3.0	1.2	1.2	1.6	1.1	1.6	1.7	0.9	1.2
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.2	1.5	1.4	0.8	1.1	0.9	0.8	0.4	1.5
Number of full brothers	1.0	1.3	2.7	0.5	-1.0	-1.4	-1.0	-1.6	-1.3	-0.6	-1.1
Emphysema/chronic bronchitis	1.0	1.1	1.8	1.1	1.2	0.2	1.3	0.5	0.8	1.3	1.3
Osteoporosis (self-reported)	1.0	1.3	2.2	-1.5	-1.2	-1.3	-0.9	-1.2	-1.1	0.1	-1.1
Reaction Time	0.9	1.7	5.4	2.3	1.2	1.1	1.3	1.0	1.1	0.7	1.1
HbA1C	0.9	1.0	1.8	0.7	1.0	0.4	1.1	1.3	0.8	1.3	1.0
Multivitamins +/- minerals	0.9	1.1	1.5	-0.0	-1.1	-1.2	-1.2	-1.1	-1.2	-0.9	-1.1
Nervous feelings	0.9	1.7	9.7	3.1	0.9	1.4	0.5	0.6	0.7	-0.0	0.7
Forced vital capacity (FVC)	0.9	3.3	12.6	-3.5	-1.8	-1.9	-1.2	-1.1	-1.2	0.8	-1.5
Number of live births	0.9	1.3	3.9	2.0	1.0	1.0	0.8	0.8	1.3	0.7	0.9
Lung cancer (father)	0.9	1.1	4.1	-0.5	-1.1	-0.1	-1.1	-0.4	-0.7	-2.0	-1.2
Exposure to tobacco smoke at home	0.9	1.0	2.4	-0.5	-0.8	-1.4	-1.0	-1.5	-1.0	-0.2	-0.8
Pulse wave peak to peak time	0.9	1.1	2.1	-0.0	-1.1	-0.7	-1.0	-0.9	-1.4	-1.2	-1.1
Mean time to correctly identify matches	0.9	1.7	7.4	2.7	1.1	0.7	1.0	0.3	0.9	1.2	0.9
Whole body fat mass	0.9	3.8	4.8	-2.2	-2.1	-1.7	-2.1	-1.8	-2.1	-1.4	-2.0
Medication: Aspirin	0.9	1.1	1.6	-0.7	-1.2	-1.1	-1.2	-1.3	-1.0	-0.7	-1.1
Unable to work because of sickness or disability	0.9	1.2	2.1	0.7	-1.0	-0.9	-1.0	-1.2	-1.2	-1.5	-1.1
Alcohol drinker status: Previous	0.9	1.0	5.9	-0.4	-0.6	0.1	-0.7	0.0	-1.1	-2.4	-0.6
Average weekly spirits intake	0.8	1.0	1.8	-0.3	1.2	0.9	1.4	1.1	1.0	0.3	1.3
Chronic bronchitis/emphysema (father)	0.8	0.9	1.9	-1.4	-0.8	-1.0	-0.8	-0.9	-0.8	-1.1	-0.7
High blood pressure (mother)	0.8	1.1	3.5	1.9	0.6	1.5	0.7	1.1	0.8	-0.2	0.5
Hearing difficulty/problems with background noise	0.8	1.2	2.4	0.7	1.2	1.6	1.1	1.2	1.1	0.1	1.2
Allergy	0.8	1.9	5.8	-0.8	0.9	1.2	0.8	1.2	1.8	2.4	1.0
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	4.0	-0.8	-1.0	-0.1	-0.9	-0.1	-0.9	-2.0	-1.1
Medication: Ramipril	0.8	1.1	2.4	-0.4	-0.9	-1.0	-0.7	-1.0	-1.4	-1.6	-0.8
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	10.6	-3.3	-1.8	-1.6	-1.1	-0.8	-1.2	0.3	-1.5
Happiness	0.8	0.9	1.2	0.5	1.1	1.0	1.0	0.8	1.1	1.1	1.1
Illnesses of mother	0.8	1.0	3.1	-1.8	-0.8	-1.0	-0.7	-0.7	-0.9	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	8.0	-2.8	-1.8	-1.7	-1.3	-0.8	-1.1	0.2	-1.5
Headache pain in last month	0.8	1.4	2.6	1.0	1.5	1.1	1.4	0.9	0.6	-1.1	1.6
Medication: Aspirin	0.8	1.1	1.7	-0.4	-1.0	-1.0	-1.0	-1.3	-1.2	-1.0	-1.0
Osteoarthritis (self-reported)	0.8	1.0	1.9	-0.1	1.1	1.4	1.4	1.2	0.5	0.1	1.2
Wears glasses or contact lenses	0.8	1.0	1.6	-1.2	-1.1	-0.4	-0.8	-0.7	-1.1	-1.3	-1.1
Commuting to job workplace: Public transport	0.8	1.0	1.8	-0.7	1.0	0.4	1.2	1.0	0.6	1.4	1.2
Alzheimer’s Disease (including proxy)	0.7	1.0	2.9	-1.7	-1.1	-1.0	-0.8	-0.5	-0.9	-0.4	-0.9
Body Mass Index (BMI) (2010)	0.7	0.9	5.5	0.8	0.1	0.9	0.0	0.3	-0.7	-2.4	0.0
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.1	0.1	-0.7	0.1	-1.1	-0.8	-1.0	-1.8	-0.8
Medication: Co-codamol	0.7	0.9	5.2	-0.5	-0.5	0.4	-0.6	0.4	-0.5	-2.3	-0.4
Diabetes (father)	0.7	0.8	1.4	0.7	1.1	0.2	1.1	0.6	0.9	1.0	1.2
Maternal smoking around birth	0.7	1.1	2.0	-0.2	-1.2	-0.8	-1.1	-0.8	-1.1	-1.4	-1.2
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	2.0	1.4	0.2	1.4	-0.0	0.6	0.4	-1.1	0.1
Had other major operations	0.7	0.9	1.5	0.5	1.0	0.9	1.2	0.8	0.6	1.2	1.0
Worrier / anxious feelings	0.7	1.3	8.6	2.9	0.6	0.6	0.2	0.3	0.7	0.2	0.4
Forced vital capacity (FVC), Best measure	0.7	2.7	11.1	-3.3	-1.6	-1.7	-1.1	-0.7	-0.9	1.0	-1.3
Wheeze or whistling in the chest in last year	0.7	1.2	3.1	1.8	1.1	1.1	1.0	0.9	1.0	0.3	1.1
Age at first live birth	0.7	1.2	2.4	-0.2	-1.1	-1.5	-1.3	-1.3	-1.1	-0.3	-1.1
Risk taking	0.7	1.1	3.6	1.9	1.1	1.0	1.0	0.6	0.7	0.3	0.9
Bipolar Disorder or Schizophrenia	0.6	1.6	6.3	1.6	0.7	-0.3	0.7	0.5	1.4	2.5	0.7
HDL Cholesterol	0.6	1.1	2.8	1.4	0.8	1.7	0.6	1.0	1.1	0.4	0.7
Lupus	0.6	0.9	2.2	-0.4	0.7	0.4	1.1	1.1	0.8	1.5	0.8
Waist Hip Ratio (WHR)	0.6	2.8	7.0	2.6	1.1	2.6	0.8	1.7	1.8	0.0	0.9
Tanning	0.6	6.7	9.5	1.0	2.6	2.9	2.8	2.8	3.1	2.4	2.7
Length of working week for main job	0.6	0.6	0.8	0.9	0.9	0.9	0.9	0.8	-0.1	-0.9	0.8
Worry too long after embarrassment	0.6	1.0	3.4	1.8	0.8	1.3	0.9	0.6	0.6	-0.6	0.8
Medication: Omeprazole	0.6	0.8	1.2	-0.6	-1.1	-0.6	-1.1	-0.6	-0.9	-1.0	-1.1
Worry (Nagel 2018)	0.5	1.0	5.8	2.4	0.6	1.0	0.4	0.5	0.7	0.3	0.5
Irritable Bowel Disease (IBD)	0.5	1.2	3.6	1.9	-0.5	-1.1	-1.2	-1.6	-0.3	-0.4	-0.7
Age at First Birth	0.5	0.7	1.6	-0.6	-0.8	-1.3	-1.0	-0.7	-0.8	-0.2	-0.8
LDL Cholesterol	0.5	0.8	4.0	-0.9	-0.2	0.5	0.1	0.6	-0.8	-2.0	-0.1
Neuroticism (2016)	0.5	0.7	1.3	1.0	-0.6	-0.7	-0.6	-1.1	-0.3	1.0	-0.7
Triglycerides	0.5	0.8	1.1	-0.0	0.9	0.7	1.0	1.0	1.1	1.0	0.9
Neuroticism	0.5	1.1	4.9	2.2	0.7	1.2	0.6	0.6	1.0	0.5	0.6
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.9	0.6	-0.7	-0.7	-1.0	-1.4	-0.7	-0.7	-0.9
Medication for hormone replacement therapy	0.5	0.6	1.1	0.0	1.0	0.9	1.0	0.7	0.4	0.7	1.1
Diabetes (mother)	0.5	0.7	2.1	0.5	1.0	0.6	1.4	0.6	0.3	0.4	1.1
Pack years adult smoking proportion	0.5	0.7	1.3	-1.1	-0.6	-0.4	-0.8	-0.6	-1.1	-1.1	-0.6
Had menopause	0.5	0.6	3.3	1.8	0.2	-0.8	-0.3	-0.7	0.0	0.6	0.1
Neuroticism score	0.5	1.1	6.3	2.5	0.5	1.3	0.2	0.3	0.5	-0.5	0.3
Weight	0.5	2.2	4.8	-2.2	-1.6	-1.3	-1.6	-1.1	-1.4	-0.3	-1.6
Noisy workplace	0.5	0.7	3.8	0.7	0.3	0.6	-0.1	0.6	-0.2	-1.9	0.2
Pulse wave Arterial Stiffness index	0.5	0.6	1.4	-0.4	0.7	0.4	0.7	0.6	1.2	1.1	0.8
Alcohol intake frequency.	0.5	1.1	3.6	-0.1	-0.9	-0.5	-1.3	-0.6	-1.1	-1.9	-1.0
Family relationship satisfaction	0.5	0.6	2.5	1.6	0.5	0.9	0.3	0.4	0.8	0.5	0.4
Illnesses of siblings: Diabetes	0.5	0.6	2.9	1.7	0.0	0.2	-0.1	-0.3	0.5	1.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	3.9	-1.3	-0.3	-1.5	0.2	-0.5	0.0	2.0	-0.1
Guilty feelings	0.5	0.8	4.5	2.1	0.4	1.0	0.2	0.2	0.7	-0.2	0.3
Ever taken oral contraceptive pill	0.5	0.6	1.4	0.8	0.5	0.8	0.8	1.2	1.0	-0.1	0.6
Financial situation satisfaction	0.5	0.6	1.5	1.2	0.6	1.2	0.6	0.5	0.7	0.1	0.5
Irritability	0.5	0.8	3.8	2.0	0.7	0.9	0.3	0.4	0.7	0.2	0.6
Age started oral contraceptive pill	0.5	0.7	1.4	-0.3	1.1	0.2	1.1	0.7	0.6	0.8	1.2
Schizophrenia (2018)	0.4	0.7	2.9	1.1	-0.2	-1.0	-0.4	-0.6	0.5	1.7	-0.2
Ulcerative Colitis (UC)	0.4	0.7	3.6	1.9	0.6	0.0	0.1	0.0	0.9	0.6	0.6
Schizophrenia (2014)	0.4	0.8	3.6	1.2	0.2	-0.6	0.2	0.2	0.9	1.9	0.2
Systolic Blood Pressure	0.4	2.0	8.7	3.0	1.0	1.8	0.7	1.0	1.2	0.1	0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.1	0.5	-0.5	-0.4	-0.9	-0.7	-0.4	-1.1	-0.5
Body mass index (BMI)	0.4	1.6	2.9	0.9	1.3	1.7	1.1	1.5	1.3	0.7	1.3
Leg predicted mass (left)	0.4	2.0	4.4	-2.1	-1.5	-1.5	-1.5	-0.8	-0.9	0.9	-1.5
Alcohol usually taken with meals	0.4	0.6	1.1	-0.5	0.7	0.3	1.0	1.1	0.7	0.9	0.8
Diabetes (self-reported)	0.4	0.7	4.2	2.0	-0.2	0.1	-0.9	-0.5	0.2	0.2	-0.5
Arm fat percentage (right)	0.4	1.4	2.0	-0.5	-1.2	-1.1	-1.4	-1.4	-1.2	-1.1	-1.2
Hip circumference	0.4	1.8	3.4	-1.9	-1.3	-1.4	-1.3	-1.3	-1.4	-0.4	-1.2
Breastfed as a baby	0.4	0.5	1.9	-0.1	0.5	0.6	0.7	0.6	0.8	1.4	0.5
Tense / ‘highly strung’	0.4	0.6	2.0	1.4	0.7	0.6	0.6	0.1	0.6	1.0	0.6
Peak expiratory flow (PEF)	0.4	0.9	5.0	-2.2	-0.8	-0.8	-0.4	0.0	-0.6	-0.0	-0.6
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.5	-1.2	0.4	-1.0	0.5	-0.5	-0.1	1.0	0.6
Medication: Allopurinol	0.4	0.6	1.2	-0.0	-0.8	-0.1	-0.9	-0.7	-0.9	-1.1	-0.8
Suffer from ‘nerves’	0.4	0.6	3.1	1.8	0.4	0.2	0.2	-0.4	0.6	1.1	0.3
Leg pain on walking	0.4	0.5	1.0	-0.1	0.7	0.9	0.7	1.0	0.6	-0.0	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.6	-1.3	-0.7	0.3	-0.2	0.2	-0.3	-0.8	-0.7
Average weekly red wine intake	0.4	0.5	0.9	-0.7	-0.7	-1.0	-0.4	-0.3	-0.9	-0.9	-0.6
Qualifications: nursing, teaching	0.4	0.6	1.0	-0.7	-0.9	-1.0	-0.7	-0.9	-0.7	0.2	-0.8
Miserableness	0.4	0.7	3.8	0.4	-0.3	0.2	-0.5	-0.5	-0.9	-1.9	-0.3
Fractured/broken bones in last 5 years	0.4	0.6	1.6	-0.8	-0.7	-1.3	-0.6	-0.8	-0.2	0.5	-0.6
Major Depression (MDD)	0.3	0.3	1.2	0.5	0.2	1.1	0.0	0.6	0.6	-0.4	0.1
Coronary Artery Disease (CAD)	0.3	0.4	1.0	0.5	-0.6	-0.5	-0.6	-0.4	-0.6	-1.0	-0.6
BMI	0.3	1.9	2.8	1.5	1.2	1.7	1.0	1.6	1.6	1.1	1.1
Leg fat-free mass (left)	0.3	1.8	4.2	-2.0	-1.4	-1.4	-1.5	-0.7	-0.8	0.9	-1.4
Taking other prescription medications	0.3	0.4	1.0	-0.3	-0.6	-0.7	-0.6	-0.4	-0.6	-1.0	-0.6
Medication: Simvastatin	0.3	0.4	1.0	-0.1	-0.8	-0.2	-1.0	-0.1	-0.2	-0.8	-0.8
Father’s age at death	0.3	0.4	0.8	0.7	0.6	0.2	0.6	0.5	0.6	0.9	0.6
Glaucoma (self-reported)	0.3	0.3	1.0	0.4	-0.1	-0.9	0.2	-1.0	-0.5	0.7	-0.1
Medication: Amlodipine	0.3	0.4	1.1	-0.0	-0.9	-0.2	-1.0	-0.3	0.0	0.0	-1.0
Medication: Seretide 50 evohaler	0.3	0.3	0.9	-0.4	0.0	-0.6	-0.1	-0.8	-0.7	-1.0	0.1
Leg fat mass (right)	0.3	1.0	1.9	-1.1	-1.0	-0.3	-1.2	-0.6	-1.1	-1.4	-1.0
Smoking status: Previous	0.3	0.4	0.9	0.9	0.6	0.3	0.7	0.5	0.6	0.9	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.8	0.1	0.4	-0.4	0.8	0.3	0.4	1.3	0.5
Average weekly beer plus cider intake	0.3	0.4	1.9	1.4	-0.3	0.4	-0.8	-0.5	0.1	-0.4	-0.5
Depressed Affect (Nagel 2018)	0.2	0.4	1.1	1.0	0.5	1.1	0.2	0.3	0.3	-0.6	0.3
Neuroticism (Nagel 2018)	0.2	0.6	3.6	1.9	0.1	0.7	-0.3	-0.2	0.1	-0.5	-0.1
Ovarian Cancer	0.2	0.3	0.9	-0.4	-0.5	-0.2	-0.9	-0.1	-0.3	-0.8	-0.5
Prostate Cancer	0.2	0.3	0.8	-0.5	-0.2	0.9	0.0	0.8	0.2	-0.5	-0.2
Bipolar Disorder (2011)	0.2	0.2	1.2	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cardiovascular Disease	0.2	0.5	1.1	1.0	-0.2	0.9	-0.5	1.1	0.6	-0.9	-0.3
Respiratory disease	0.2	0.4	1.0	0.1	-0.2	-1.0	-0.0	-0.6	-1.0	-0.8	-0.2
Lung FEV1/FVC ratio	0.2	1.2	1.6	-1.1	-1.2	-1.0	-1.1	-0.7	-1.2	-1.3	-1.1
Chronotype (morning person)	0.2	0.6	3.8	1.9	0.1	0.5	-0.2	-0.3	0.2	-0.4	-0.0
Number of treatments/medications taken	0.2	0.4	0.8	0.9	0.7	0.4	0.5	0.7	0.6	0.3	0.7
Sensitivity / hurt feelings	0.2	0.3	0.7	0.8	-0.4	0.1	-0.4	-0.8	-0.1	-0.7	-0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.9	0.9	-0.2	-0.1	-0.3	-0.2	-0.4	-0.6	-0.2
Medication: Metformin	0.2	0.3	0.8	0.9	-0.5	-0.1	-0.9	0.1	0.4	0.3	-0.6
Age when periods started (menarche)	0.2	0.4	1.1	-1.0	0.5	-0.1	0.8	0.5	0.3	-0.3	0.7
Stomach or abdominal pain in last month	0.2	0.2	0.5	0.3	0.5	0.4	0.4	0.5	0.4	-0.7	0.6
Medication: Atenolol	0.2	0.2	0.4	0.4	0.4	0.7	0.6	0.5	0.4	-0.3	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	2.0	1.4	-0.3	0.1	-0.4	-0.3	0.1	-0.7	-0.5
Hair/balding pattern: Pattern 2	0.2	0.2	0.7	0.8	-0.4	-0.7	-0.5	-0.5	-0.1	0.1	-0.4
Financial difficulties in last 2 years	0.2	0.2	1.1	0.1	-0.2	0.8	-0.3	0.0	-0.2	-1.1	-0.3
Time employed in main current job	0.2	0.2	0.6	-0.6	0.4	-0.4	0.8	0.2	-0.5	0.2	0.5
Pulse rate	0.2	0.4	1.0	-0.7	0.4	-1.0	0.3	-0.1	-0.2	1.0	0.5
Arm fat mass (right)	0.2	1.0	1.6	-1.1	-1.1	-0.8	-1.3	-0.9	-1.0	-0.7	-1.1
Pulse wave reflection index	0.2	0.2	0.6	-0.1	-0.7	0.1	-0.5	-0.2	-0.1	-0.8	-0.7
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.8	0.9	0.5	0.7	0.2	0.4	0.4	-0.0	0.5
Birth weight	0.2	0.4	1.8	-0.6	-0.1	1.4	-0.2	0.9	0.0	-0.7	-0.1
Leg fat percentage (right)	0.2	0.6	3.0	-0.4	-0.5	0.4	-0.7	-0.3	-0.7	-1.7	-0.5
Number of children fathered	0.2	0.2	1.3	-0.3	0.1	-0.1	0.4	0.4	-0.3	-1.1	0.2
Qualifications: College or University degree	0.2	0.5	1.7	-0.1	-0.4	-1.3	-0.5	-0.8	-0.8	0.5	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	0.3	0.6	0.5	0.7	0.5	0.3	0.2	0.6
Pulse rate, automated reading	0.2	0.5	1.4	0.7	1.1	-0.1	0.8	0.4	0.2	0.3	1.2
Number of full sisters	0.2	0.2	0.9	0.4	0.4	0.1	0.3	0.4	0.1	-1.0	0.4
Chest pain or discomfort	0.2	0.2	0.9	-0.3	-0.3	-0.3	-0.3	-0.2	-0.7	-0.9	-0.3
Age at last live birth	0.2	0.3	0.6	0.5	-0.6	-0.7	-0.8	-0.6	-0.5	-0.4	-0.6
Leg fat-free mass (right)	0.2	1.2	2.9	-1.7	-1.1	-1.1	-1.1	-0.3	-0.5	1.2	-1.1
Arm fat percentage (left)	0.2	0.9	1.2	-0.6	-0.9	-0.7	-1.1	-1.0	-1.0	-1.1	-0.9
Diabetes diagnosed by doctor	0.2	0.4	2.2	1.5	-0.1	0.2	-0.6	-0.2	0.3	-0.1	-0.3
Breast cancer (self-reported)	0.2	0.2	0.6	-0.1	-0.5	-0.4	-0.2	-0.2	-0.8	-0.6	-0.5
Medication: Gliclazide	0.2	0.2	0.7	0.7	0.1	0.3	0.1	0.2	0.7	0.8	0.0
Leg predicted mass (right)	0.2	1.2	3.0	-1.7	-1.1	-1.2	-1.2	-0.4	-0.5	1.3	-1.1
Arm fat mass (left)	0.2	0.7	1.1	-1.0	-0.9	-0.6	-1.0	-0.7	-0.9	-0.6	-0.9
Number of self-reported non-cancer illnesses	0.2	0.3	0.8	0.4	0.4	0.5	0.3	0.9	0.6	-0.1	0.5
Mother’s age at death	0.2	0.2	0.8	-0.4	0.0	-0.8	-0.1	-0.3	0.3	0.9	0.1
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	0.7	0.4	0.0	0.8	-0.0	0.0	0.7	0.4
Medication: Blood pressure	0.2	0.4	2.1	1.4	0.3	0.6	0.2	0.5	0.5	0.1	0.2
Illnesses of father: High blood pressure	0.2	0.3	1.3	1.2	-0.0	0.2	-0.3	0.5	0.2	-0.8	-0.1
Alcohol drinker status: Never	0.2	0.2	0.9	0.3	0.4	-0.4	0.2	-0.5	0.2	1.0	0.3
Ever smoked	0.2	0.3	1.0	1.0	0.4	-0.2	0.6	0.2	0.3	0.7	0.4
Basal metabolic rate	0.2	1.0	3.5	-1.9	-1.0	-0.7	-1.1	-0.3	-0.5	0.8	-1.0
Diastolic blood pressure, automated reading	0.2	0.5	0.8	0.9	0.8	0.6	0.8	0.7	0.5	-0.1	0.8
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.1	-0.5	0.7	0.4	1.1	0.6	0.5	0.6	0.8
Heart disease (siblings)	0.2	0.2	0.9	1.0	-0.4	0.1	-0.5	-0.3	-0.2	-0.4	-0.5
Pack years of smoking	0.2	0.3	0.6	-0.8	-0.3	-0.1	-0.5	-0.4	-0.7	-0.8	-0.3
Leg fat mass (left)	0.2	0.8	1.5	-1.0	-0.9	-0.2	-1.1	-0.5	-0.9	-1.2	-0.9
Depression (Nagel 2018)	0.1	0.2	1.1	0.4	-0.1	-0.4	-0.3	-1.0	-0.4	-0.3	-0.2
Alzheimer’s Disease (in mother)	0.1	0.1	0.6	-0.8	-0.2	0.1	-0.1	0.3	0.0	0.4	-0.1
Rheumatoid Arthritis	0.1	0.1	0.6	-0.1	-0.1	-0.2	-0.3	-0.3	0.2	0.8	-0.1
Heel T-Score	0.1	1.1	5.3	0.1	0.6	-0.8	0.7	-0.1	1.0	2.3	0.8
Smoking Status	0.1	0.2	0.6	0.5	0.1	-0.8	0.4	-0.6	-0.1	0.4	0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	0.5	-0.3	0.1	-0.8	0.1	0.3	-0.4	-0.4
Systolic blood pressure, automated reading	0.1	0.4	1.7	1.3	0.5	0.5	0.4	0.2	0.4	-0.0	0.5
Fed-up feelings	0.1	0.2	1.3	0.4	0.1	0.5	0.0	0.0	-0.4	-1.1	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.5	0.6	0.1	-0.1	0.1	-0.1	-0.2	-0.7	0.1
High blood pressure	0.1	0.2	1.0	1.0	-0.1	0.4	-0.3	0.3	0.1	-0.3	-0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.4	-0.0	0.0	-0.0	0.0	0.3	0.2	-0.7	0.1
Waist circumference	0.1	0.4	1.2	0.5	0.5	1.1	0.3	0.7	0.6	0.3	0.4
Past tobacco smoking	0.1	0.3	0.7	-0.8	-0.5	-0.2	-0.8	-0.4	-0.3	-0.3	-0.5
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.6	-0.0	-0.1	0.4	-0.4	0.2	0.2	-0.8	-0.2
Pain all over the body in last month	0.1	0.2	0.6	0.8	0.2	0.4	0.0	0.2	0.5	0.4	0.1
Trunk fat-free mass	0.1	0.6	2.0	-1.4	-0.5	-0.2	-0.6	0.2	0.1	1.4	-0.5
Alcohol intake versus 10 years previously	0.1	0.1	0.3	0.6	-0.1	0.1	-0.2	-0.0	-0.1	0.5	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.0	1.0	0.0	0.3	-0.1	-0.0	-0.2	-0.7	-0.1
Mouth/teeth dental problems: Dentures	0.1	0.2	0.9	-0.5	-0.3	-0.1	-0.4	-0.3	0.2	1.0	-0.3
Asthma	0.1	0.2	0.6	0.8	0.0	-0.6	0.1	-0.4	-0.5	-0.3	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.4	0.6	0.3	0.3	0.1	0.3	0.4	-0.1	0.3
Trunk predicted mass	0.1	0.6	2.0	-1.4	-0.5	-0.1	-0.6	0.2	0.1	1.4	-0.5
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.4	-0.5	0.1	-0.6	0.4	-0.1	-0.2	0.5	0.1
Gout (self-reported)	0.1	0.1	0.6	0.8	0.1	0.3	-0.1	-0.2	-0.1	-0.2	0.1
Arm fat-free mass (right)	0.1	0.4	1.6	-1.2	-0.1	0.5	-0.2	0.7	0.1	0.8	-0.1
Medication for pain relief, constipation, heartburn	0.1	0.1	0.4	-0.2	0.0	0.6	0.2	0.5	0.3	0.6	-0.1
Medication: Blood pressure	0.1	0.2	0.7	0.4	-0.0	0.8	-0.3	0.1	-0.1	-0.8	-0.1
Migraine (self-reported)	0.1	0.2	0.4	-0.6	0.5	0.2	0.1	0.3	0.1	-0.5	0.5
Medication: Ibuprofen	0.1	0.1	0.4	0.6	-0.2	-0.3	-0.3	-0.0	0.1	-0.0	-0.3
Heart disease (mother)	0.1	0.1	0.4	0.4	0.1	0.6	0.3	0.7	0.2	-0.3	0.1
Arm predicted mass (right)	0.1	0.5	2.3	-1.5	-0.1	0.3	-0.2	0.6	0.1	1.0	-0.1
Overall health rating	0.1	0.1	0.3	0.6	-0.2	-0.4	-0.4	0.2	-0.0	-0.3	-0.2
Had major operations	0.1	0.2	0.7	-0.1	0.3	-0.1	0.2	-0.5	0.1	0.9	0.3
Knee pain experienced in last month	0.1	0.2	0.4	0.1	0.5	0.3	0.6	0.6	0.2	0.0	0.7
Hypertension (Self-reported)	0.1	0.3	1.4	1.2	0.3	0.8	0.1	0.6	0.4	-0.3	0.2
Whole body fat-free mass	0.1	0.8	2.8	-1.7	-0.7	-0.6	-0.8	-0.1	-0.2	1.3	-0.7
Loneliness, isolation	0.1	0.1	0.5	-0.1	-0.2	0.6	-0.2	-0.0	0.1	-0.7	-0.3
Ever had bowel cancer screening	0.1	0.1	0.5	0.2	0.3	0.1	0.1	0.0	0.5	0.7	0.3
Friendships satisfaction	0.1	0.1	0.4	0.4	0.1	0.6	0.1	0.1	0.2	0.0	0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.3	-0.5	-0.1	0.5	-0.1	0.5	0.1	-0.5	0.0
Asthma (self-reported)	0.1	0.1	0.5	0.7	0.2	-0.4	0.3	-0.1	-0.3	-0.2	0.2
Whole body water mass	0.1	0.8	2.9	-1.7	-0.7	-0.5	-0.8	-0.1	-0.1	1.3	-0.7
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.3	-0.6	0.0	-0.6	0.0	-0.1	-0.2	-0.2	0.1
Leg fat percentage (left)	0.1	0.4	2.4	-0.2	-0.3	0.6	-0.4	-0.0	-0.5	-1.5	-0.3
Arm fat-free mass (left)	0.1	0.5	2.3	-1.5	-0.4	-0.1	-0.6	0.3	-0.1	0.7	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.4	0.1	-0.5	-0.6	-0.4	-0.2	-0.5	0.0	-0.5
Arm predicted mass (left)	0.1	0.5	2.2	-1.5	-0.5	-0.1	-0.7	0.2	-0.2	0.8	-0.5
Blood Red Count	0.0	0.3	1.3	0.6	0.4	0.2	0.1	0.6	1.1	0.5	0.4
Hair Pigment	0.0	0.8	3.2	-0.3	0.3	1.4	0.4	0.8	-0.4	-1.8	0.3
Ever had hysterectomy (womb removed)	0.0	0.1	0.2	-0.3	0.1	-0.1	-0.2	-0.2	-0.1	-0.5	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.4	0.4	0.0	-0.2	0.1	-0.3	-0.2	-0.6	0.1
Mouth/teeth dental problems	0.0	0.0	0.0	0.1	0.1	-0.1	0.2	0.2	0.1	0.0	0.1
Hair/balding pattern: Pattern 4	0.0	0.1	0.3	0.4	-0.1	-0.1	-0.4	-0.5	0.3	0.2	-0.2
Blood clot in the leg (DVT)	0.0	0.1	0.1	0.3	-0.2	-0.4	-0.1	-0.0	-0.3	0.3	-0.2
Comparative body size at age 10	0.0	0.1	0.2	0.2	-0.4	-0.3	-0.2	-0.2	-0.3	0.3	-0.5
Shortness of breath walking on level ground	0.0	0.0	0.3	0.6	0.1	-0.2	0.0	0.1	0.1	-0.1	0.0
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.1	0.2	0.2	-0.0	0.3	0.0	0.1	0.1	0.2
Medication for cholesterol	0.0	0.1	0.2	-0.5	-0.0	0.1	0.3	0.1	0.3	0.1	0.0

Hub : Genes

PIP5K1A

Models

Trait associations