[Hub]/) : Traits : Standing height :

chr2:22,911,727-26,262,948

Best TWAS P=1.92e-65 · Best GWAS P=1.78e-66 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADCY3 0.16 0.12 lasso 10 0.14 3.2e-17 -15.20 12.5 7.5e-36 0.26 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex CENPO 0.07 0.03 bslmm 322 0.03 7.0e-05 -7.12 15.3 4.5e-53 0.23 0.63 0.01 TRUE
3 CommonMind Brain Pre-frontal Cortex DNAJC27 0.14 0.14 lasso 5 0.14 2.0e-16 -5.20 5.2 2.0e-07 0.15 1.00 0.00 FALSE
4 CommonMind Brain Pre-frontal Cortex UBXN2A 0.22 0.18 enet 28 0.24 3.0e-28 -7.75 6.5 6.0e-11 0.03 1.00 0.00 FALSE
5 GTEx Adipose Subcutaneous TP53I3 0.11 0.03 enet 48 0.04 3.8e-04 -2.82 8.0 1.6e-15 0.05 0.18 0.48 FALSE
6 GTEx Adipose Subcutaneous ADCY3 0.07 0.04 lasso 6 0.01 3.2e-02 -14.89 -14.7 5.7e-49 -0.31 0.82 0.02 FALSE
7 GTEx Adipose Subcutaneous UBXN2A 0.06 0.04 lasso 5 0.04 5.2e-04 -9.79 -8.2 2.1e-16 -0.06 0.28 0.69 FALSE
8 GTEx Adipose Subcutaneous RP11-443B20.1 0.04 0.00 enet 10 0.00 1.2e-01 -6.54 -11.5 8.3e-31 -0.28 0.35 0.08 FALSE
9 GTEx Adipose Visceral Omentum NCOA1 0.11 0.02 enet 17 0.02 2.1e-02 -7.62 -7.2 4.0e-13 -0.12 0.18 0.04 FALSE
10 GTEx Adipose Visceral Omentum UBXN2A 0.10 0.08 enet 29 0.03 9.8e-03 -10.71 -8.0 1.9e-15 -0.05 0.09 0.89 FALSE
11 GTEx Adrenal Gland UBXN2A 0.42 0.08 enet 35 0.22 2.6e-08 -4.12 -5.7 1.6e-08 -0.05 0.05 0.95 FALSE
12 GTEx Adrenal Gland PFN4 0.20 0.15 lasso 2 0.18 3.9e-07 -6.41 -5.3 1.3e-07 -0.02 0.22 0.05 FALSE
13 GTEx Adrenal Gland PTRHD1 0.32 0.28 lasso 3 0.26 8.3e-10 13.67 -13.9 8.7e-44 -0.21 0.98 0.00 FALSE
14 GTEx Artery Aorta NCOA1 0.15 0.00 enet 15 0.01 1.4e-01 -12.25 -12.4 3.1e-35 -0.21 0.07 0.04 FALSE
15 GTEx Artery Aorta UBXN2A 0.20 0.09 lasso 6 0.08 4.1e-05 -3.77 -5.6 1.8e-08 -0.04 0.85 0.15 FALSE
16 GTEx Artery Coronary DNAJC27 0.12 0.03 lasso 7 0.00 2.4e-01 -5.30 -8.2 1.7e-16 -0.25 0.16 0.07 FALSE
17 GTEx Artery Tibial ADCY3 0.21 0.14 lasso 6 0.15 4.3e-12 -12.89 -14.2 4.7e-46 -0.25 1.00 0.00 FALSE
18 GTEx Artery Tibial UBXN2A 0.12 0.06 enet 24 0.09 1.5e-07 -3.77 -8.4 2.9e-17 -0.06 0.86 0.14 TRUE
19 GTEx Artery Tibial RP11-443B20.1 0.17 0.08 enet 40 0.09 8.2e-08 -12.89 -13.7 1.8e-42 -0.32 0.90 0.02 FALSE
20 GTEx Brain Putamen basal ganglia PFN4 0.32 0.17 lasso 5 0.12 1.1e-03 -6.41 -5.7 1.1e-08 -0.01 0.07 0.06 FALSE
21 GTEx Breast Mammary Tissue (Male) NCOA1 0.13 -0.01 lasso 3 0.04 4.8e-02 -3.86 -7.5 7.2e-14 -0.23 0.05 0.06 TRUE
22 GTEx Cells EBV-transformed lymphocytes ADCY3 0.25 0.23 enet 10 0.12 9.2e-05 -14.89 17.1 1.9e-65 0.36 0.79 0.02 TRUE
23 GTEx Cells EBV-transformed lymphocytes PFN4 0.18 0.13 lasso 12 0.12 8.9e-05 -6.50 -7.3 2.0e-13 -0.01 0.34 0.04 FALSE
24 GTEx Cells EBV-transformed lymphocytes RP11-443B20.1 0.13 0.13 enet 9 0.05 9.2e-03 -14.89 16.5 4.4e-61 0.37 0.35 0.05 FALSE
25 GTEx Cells Transformed fibroblasts UBXN2A 0.12 0.07 enet 12 0.12 4.7e-09 -9.19 -6.6 5.3e-11 -0.04 0.46 0.53 FALSE
26 GTEx Colon Sigmoid DNMT3A 0.19 -0.01 lasso 8 0.00 4.5e-01 -6.50 -11.8 2.2e-32 -0.41 0.05 0.40 TRUE
27 GTEx Colon Transverse SF3B14 0.09 0.05 lasso 9 0.02 4.9e-02 -2.75 -5.8 5.8e-09 0.01 0.35 0.38 FALSE
28 GTEx Colon Transverse UBXN2A 0.11 0.01 enet 8 0.03 8.7e-03 -9.75 -11.3 1.7e-29 -0.09 0.08 0.69 FALSE
29 GTEx Colon Transverse PFN4 0.14 0.07 lasso 2 0.04 3.3e-03 -6.51 -6.6 4.5e-11 -0.02 0.09 0.25 FALSE
30 GTEx Esophagus Gastroesophageal Junction SF3B14 0.10 0.01 lasso 8 0.00 3.5e-01 -4.71 -7.7 1.8e-14 -0.03 0.10 0.18 FALSE
31 GTEx Esophagus Mucosa TP53I3 0.16 0.03 enet 23 0.06 8.2e-05 -0.65 -8.2 2.0e-16 -0.04 0.12 0.06 TRUE
32 GTEx Esophagus Mucosa ADCY3 0.06 0.05 lasso 3 0.03 6.8e-03 -5.30 -5.3 9.9e-08 -0.15 0.59 0.04 FALSE
33 GTEx Esophagus Mucosa PFN4 0.16 0.15 lasso 4 0.15 3.6e-10 -6.50 -6.7 2.0e-11 -0.01 1.00 0.00 TRUE
34 GTEx Esophagus Muscularis NCOA1 0.11 0.01 enet 9 0.01 5.8e-02 -9.90 -15.1 2.5e-51 -0.17 0.08 0.04 FALSE
35 GTEx Heart Atrial Appendage UBXN2A 0.08 0.02 lasso 3 0.02 5.2e-02 -5.97 -7.6 2.8e-14 -0.03 0.23 0.28 FALSE
36 GTEx Heart Left Ventricle PFN4 0.23 0.28 lasso 6 0.28 4.1e-15 -6.51 -7.5 5.3e-14 -0.03 1.00 0.00 FALSE
37 GTEx Lung NCOA1 0.12 0.04 lasso 7 0.06 1.9e-05 -2.53 -11.1 1.2e-28 -0.10 0.52 0.02 TRUE
38 GTEx Lung UBXN2A 0.09 0.06 enet 7 0.07 6.1e-06 -4.14 -8.7 2.5e-18 -0.06 0.36 0.63 FALSE
39 GTEx Lung PFN4 0.14 0.12 enet 8 0.15 7.6e-12 -6.50 -5.4 6.3e-08 -0.02 1.00 0.00 FALSE
40 GTEx Muscle Skeletal POMC 0.38 0.10 lasso 9 0.09 2.9e-09 2.80 8.4 3.1e-17 0.26 1.00 0.00 FALSE
41 GTEx Muscle Skeletal UBXN2A 0.10 0.04 lasso 7 0.03 5.5e-04 -4.16 -7.1 1.2e-12 -0.05 0.25 0.74 FALSE
42 GTEx Muscle Skeletal PFN4 0.12 0.09 lasso 4 0.09 5.6e-09 -6.50 -6.2 6.1e-10 -0.02 1.00 0.00 FALSE
43 GTEx Nerve Tibial ADCY3 0.09 0.05 enet 6 0.03 2.2e-03 -12.89 15.9 3.3e-57 0.34 0.97 0.00 FALSE
44 GTEx Nerve Tibial PFN4 0.25 0.16 lasso 5 0.20 3.8e-14 -6.50 -5.5 5.1e-08 -0.02 1.00 0.00 FALSE
45 GTEx Nerve Tibial RP11-443B20.1 0.07 0.03 enet 6 0.02 1.1e-02 -12.89 13.8 3.7e-43 0.28 0.74 0.02 FALSE
46 GTEx Pituitary PFN4 0.34 0.03 lasso 14 0.02 1.1e-01 -6.41 -5.3 1.4e-07 0.00 0.04 0.06 FALSE
47 GTEx Prostate FAM228B 0.16 0.02 enet 31 0.07 9.6e-03 -10.62 5.4 5.9e-08 0.03 0.16 0.06 TRUE
48 GTEx Skin Sun Exposed Lower leg UBXN2A 0.08 0.04 enet 17 0.03 1.3e-03 -9.73 -7.7 1.6e-14 -0.07 0.56 0.35 FALSE
49 GTEx Small Intestine Terminal Ileum UBXN2A 0.18 0.08 enet 33 0.16 2.5e-04 -10.62 -10.3 1.1e-24 -0.05 0.03 0.89 TRUE
50 GTEx Spleen UBXN2A 0.31 0.11 enet 19 0.17 4.1e-05 11.03 -12.2 2.4e-34 -0.07 0.04 0.92 TRUE
51 GTEx Stomach UBXN2A 0.13 0.14 enet 5 0.14 3.6e-07 -3.77 -6.4 1.2e-10 -0.07 0.59 0.31 FALSE
52 GTEx Testis FAM228B 0.14 0.09 enet 11 0.10 3.3e-05 8.14 7.5 8.4e-14 0.03 0.64 0.02 FALSE
53 GTEx Whole Blood DNAJC27 0.08 0.10 lasso 1 0.10 2.2e-09 -14.39 -14.4 5.7e-47 -0.31 1.00 0.00 FALSE
54 GTEx Whole Blood ADCY3 0.23 0.24 enet 24 0.27 5.5e-25 -14.60 -14.9 3.8e-50 -0.31 1.00 0.00 FALSE
55 GTEx Whole Blood UBXN2A 0.17 0.07 lasso 8 0.09 2.1e-08 -4.16 -9.7 3.5e-22 -0.05 0.04 0.96 FALSE
56 GTEx Whole Blood RP11-443B20.1 0.21 0.17 enet 32 0.20 1.8e-18 -14.39 -14.2 1.2e-45 -0.31 1.00 0.00 TRUE
57 METSIM Adipose EFR3B 0.04 0.00 bslmm 357 0.00 9.7e-02 5.12 6.9 7.0e-12 -0.06 0.06 0.03 FALSE
58 METSIM Adipose POMC 0.18 0.06 lasso 9 0.09 5.5e-13 6.24 7.1 1.0e-12 0.13 1.00 0.00 FALSE
59 METSIM Adipose UBXN2A 0.07 0.03 bslmm 403 0.06 5.3e-10 -9.73 -7.0 2.2e-12 -0.03 0.91 0.09 FALSE
60 NTR Blood ITSN2 0.02 0.00 bslmm 345 0.01 2.9e-03 -8.56 9.2 3.3e-20 0.07 0.05 0.04 TRUE
61 ROSMAP Brain Pre-frontal Cortex DNAJC27 0.10 0.06 blup 330 0.06 3.7e-08 -5.27 6.6 4.6e-11 0.29 0.99 0.01 FALSE
62 ROSMAP Brain Pre-frontal Cortex KLHL29 0.08 0.03 enet 27 0.02 1.1e-03 -1.05 -6.7 2.2e-11 -0.04 0.75 0.19 TRUE
63 ROSMAP Brain Pre-frontal Cortex ADCY3 0.17 0.26 enet 32 0.26 6.8e-33 -14.60 16.5 8.0e-61 0.36 1.00 0.00 FALSE
64 ROSMAP Brain Pre-frontal Cortex CENPO 0.08 0.04 enet 5 0.05 2.6e-07 8.18 10.0 1.0e-23 0.16 1.00 0.00 FALSE
65 ROSMAP Brain Pre-frontal Cortex UBXN2A 0.03 0.01 lasso 4 0.02 2.2e-03 -5.93 5.6 2.0e-08 -0.01 0.35 0.02 TRUE
66 ROSMAP Brain Pre-frontal Cortex PFN4 0.05 0.03 lasso 1 0.03 1.7e-04 -6.41 -6.4 1.4e-10 -0.02 0.41 0.02 FALSE
67 YFS Blood ADCY3 0.07 0.02 bslmm 343 0.04 7.3e-14 -15.16 7.1 9.3e-13 0.11 1.00 0.00 FALSE
68 YFS Blood CENPO 0.09 0.06 lasso 6 0.07 6.7e-21 -7.88 8.3 9.9e-17 0.10 1.00 0.00 FALSE
69 YFS Blood DNMT3A 0.04 0.00 bslmm 369 0.01 4.2e-05 3.33 -5.2 2.5e-07 -0.29 0.26 0.10 FALSE
70 YFS Blood POMC 0.35 0.05 enet 71 0.19 5.7e-59 13.91 10.7 7.9e-27 0.24 1.00 0.00 FALSE
71 The Cancer Genome Atlas Bladder Urothelial Carcinoma PFN4 0.11 0.00 enet 8 0.03 9.2e-04 -6.50 -5.2 1.5e-07 -0.02 0.55 0.04 FALSE
72 The Cancer Genome Atlas Breast Invasive Carcinoma ADCY3 0.05 0.03 blup 81 0.03 5.0e-07 -8.63 11.2 2.6e-29 0.17 0.82 0.11 FALSE
73 The Cancer Genome Atlas Breast Invasive Carcinoma FKBP1B 0.04 0.02 blup 41 0.02 3.6e-05 -6.50 7.0 3.1e-12 0.03 0.44 0.04 FALSE
74 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PFN4 0.19 0.16 lasso 2 0.15 5.5e-08 -6.50 -6.5 7.8e-11 -0.02 0.98 0.00 FALSE
75 The Cancer Genome Atlas Glioblastoma Multiforme ADCY3 0.36 0.14 enet 7 0.13 8.9e-05 -10.43 10.6 2.0e-26 0.11 0.04 0.06 FALSE
76 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PFN4 0.13 0.07 lasso 4 0.06 4.4e-07 -6.50 -6.1 1.1e-09 -0.02 1.00 0.00 FALSE
77 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma POMC 0.06 0.00 enet 12 0.03 9.3e-05 -1.06 5.7 1.5e-08 0.13 0.02 0.07 FALSE
78 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADCY3 0.08 0.03 enet 16 0.03 1.5e-04 -8.65 10.5 1.3e-25 0.04 0.03 0.03 FALSE
79 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EFR3B 0.03 0.05 lasso 1 0.04 1.9e-05 12.08 12.1 1.4e-33 0.33 0.55 0.06 FALSE
80 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PFN4 0.10 0.07 lasso 2 0.06 1.1e-07 -6.50 -6.5 9.3e-11 -0.02 0.98 0.00 FALSE
81 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma POMC 0.16 0.05 blup 39 0.11 2.4e-12 13.91 6.8 8.3e-12 0.16 0.92 0.08 TRUE
82 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma NCOA1 0.08 0.07 blup 77 0.05 5.8e-04 1.09 -7.4 1.7e-13 -0.05 0.14 0.51 FALSE
83 The Cancer Genome Atlas Brain Lower Grade Glioma ADCY3 0.03 0.02 blup 81 0.02 7.1e-04 -12.15 14.9 3.5e-50 0.32 0.17 0.68 FALSE
84 The Cancer Genome Atlas Brain Lower Grade Glioma PFN4 0.09 0.07 blup 43 0.08 5.3e-09 -6.41 -5.7 9.7e-09 -0.02 0.99 0.00 FALSE
85 The Cancer Genome Atlas Brain Lower Grade Glioma UBXN2A 0.04 0.04 lasso 1 0.03 1.4e-04 -5.94 5.9 2.9e-09 0.01 0.36 0.14 FALSE
86 The Cancer Genome Atlas Lung Adenocarcinoma DNAJC27 0.05 0.01 blup 46 0.04 3.2e-05 -5.27 10.6 4.9e-26 0.25 0.56 0.34 FALSE
87 The Cancer Genome Atlas Lung Adenocarcinoma NCOA1 0.02 0.01 blup 77 0.01 1.2e-02 4.08 8.2 2.1e-16 0.15 0.08 0.28 FALSE
88 The Cancer Genome Atlas Lung Adenocarcinoma PFN4 0.15 0.09 lasso 3 0.09 7.3e-11 -6.41 -6.4 1.4e-10 -0.02 1.00 0.00 FALSE
89 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ADCY3 0.06 0.01 enet 9 0.02 1.0e-03 -8.56 7.6 2.2e-14 0.05 0.06 0.04 FALSE
90 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PFN4 0.10 0.07 enet 5 0.08 5.5e-09 -6.41 -5.6 2.3e-08 -0.02 1.00 0.00 FALSE
91 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TP53I3 0.03 0.01 enet 12 0.03 3.2e-04 -5.93 5.3 1.0e-07 -0.01 0.06 0.24 FALSE
92 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UBXN2A 0.03 0.02 blup 46 0.03 5.7e-04 -4.12 -6.7 2.1e-11 -0.05 0.26 0.40 FALSE
93 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma DNAJC27 0.04 0.04 lasso 1 0.02 1.2e-02 -5.27 5.3 1.4e-07 0.15 0.09 0.05 FALSE
94 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma POMC 0.19 0.01 blup 38 0.05 1.5e-04 13.91 9.3 9.2e-21 0.26 0.02 0.20 TRUE
95 The Cancer Genome Atlas Pancreatic Adenocarcinoma DNAJC27 0.12 0.12 lasso 2 0.09 1.7e-04 -5.27 5.3 1.4e-07 0.15 0.59 0.10 FALSE
96 The Cancer Genome Atlas Pancreatic Adenocarcinoma EFR3B 0.26 0.01 lasso 4 0.05 3.8e-03 -9.90 -10.0 2.1e-23 -0.22 0.03 0.16 FALSE
97 The Cancer Genome Atlas Pancreatic Adenocarcinoma PFN4 0.20 0.18 lasso 1 0.16 4.3e-07 -6.51 -6.5 7.5e-11 -0.02 0.84 0.05 FALSE
98 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma DNAJC27 0.07 0.09 lasso 2 0.10 8.2e-05 -5.27 5.3 1.4e-07 0.15 0.21 0.13 FALSE
99 The Cancer Genome Atlas Prostate Adenocarcinoma PFN4 0.12 0.08 lasso 6 0.07 6.3e-08 -6.50 -6.2 5.1e-10 -0.02 0.99 0.00 FALSE
100 The Cancer Genome Atlas Prostate Adenocarcinoma POMC 0.11 0.08 enet 7 0.09 1.6e-09 -1.06 5.2 1.9e-07 0.10 0.97 0.02 FALSE
101 The Cancer Genome Atlas Rectum Adenocarcinoma PFN4 0.38 0.11 lasso 5 0.05 2.8e-02 -6.50 -6.6 3.2e-11 -0.02 0.02 0.06 FALSE