[Hub]/) : Traits : Height : ← →

chr1:5,887,140-12,054,911

Best TWAS P=7.38e-46 · Best GWAS P=1.85e-31 conditioned to 8.54e-10

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	EXOSC10	0.06	0.08	lasso	2	0.07	6.8e-09	10.65	10.8	2.2e-27	0.01	0.02	0.98	TRUE
2	CommonMind	Brain Pre-frontal Cortex	H6PD	0.22	0.18	lasso	3	0.18	1.9e-21	6.62	-5.9	3.0e-09	-0.17	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	MTOR	0.13	0.15	lasso	4	0.15	5.6e-18	10.70	10.3	1.1e-24	-0.03	0.01	0.99	FALSE
4	CommonMind	Brain Pre-frontal Cortex	NMNAT1	0.05	0.01	blup	314	0.02	9.7e-04	4.20	-6.5	6.1e-11	0.06	0.31	0.13	FALSE
5	GTEx	Adipose Subcutaneous	MASP2	0.10	0.06	lasso	2	0.03	8.8e-04	7.02	7.1	1.5e-12	0.04	0.59	0.17	FALSE
6	GTEx	Adipose Subcutaneous	H6PD	0.28	0.07	enet	20	0.15	3.3e-12	8.91	5.5	5.0e-08	-0.37	0.88	0.01	TRUE
7	GTEx	Adipose Subcutaneous	PEX14	0.15	0.09	enet	16	0.10	1.6e-08	6.88	-6.4	1.9e-10	-0.06	1.00	0.00	FALSE
8	GTEx	Adipose Subcutaneous	DFFA	0.11	0.08	enet	8	0.06	1.3e-05	6.88	-8.0	1.6e-15	-0.06	0.69	0.18	FALSE
9	GTEx	Adipose Subcutaneous	EXOSC10	0.17	0.00	lasso	3	0.00	1.8e-01	10.48	10.6	2.3e-26	0.01	0.03	0.33	FALSE
10	GTEx	Adipose Visceral Omentum	PEX14	0.11	0.08	lasso	2	0.07	2.2e-04	-6.74	-6.8	1.2e-11	-0.03	0.72	0.12	FALSE
11	GTEx	Adipose Visceral Omentum	EXOSC10	0.26	0.00	lasso	7	0.03	1.3e-02	1.05	6.3	3.5e-10	-0.02	0.02	0.75	FALSE
12	GTEx	Adipose Visceral Omentum	RP4-635E18.7	0.19	0.08	lasso	6	0.05	9.0e-04	10.66	10.2	3.2e-24	0.00	0.01	0.97	FALSE
13	GTEx	Adrenal Gland	PGD	0.15	0.10	lasso	2	0.02	4.3e-02	9.14	9.1	6.4e-20	0.09	0.13	0.38	FALSE
14	GTEx	Artery Tibial	VAMP3	0.20	0.05	enet	22	0.11	5.8e-09	-4.81	-6.4	1.2e-10	0.03	0.92	0.02	FALSE
15	GTEx	Artery Tibial	PGD	0.07	0.00	enet	17	0.00	2.6e-01	9.12	5.9	3.2e-09	0.06	0.07	0.35	FALSE
16	GTEx	Brain Cerebellar Hemisphere	EXOSC10	0.23	0.10	lasso	3	0.12	6.4e-04	9.96	9.9	5.9e-23	0.01	0.07	0.64	FALSE
17	GTEx	Brain Cerebellum	H6PD	0.69	0.40	lasso	9	0.42	6.8e-14	6.62	-7.2	4.5e-13	-0.12	0.99	0.00	FALSE
18	GTEx	Brain Cerebellum	EXOSC10	0.33	0.16	lasso	6	0.18	3.8e-06	10.38	10.3	6.3e-25	-0.02	0.06	0.93	FALSE
19	GTEx	Brain Cerebellum	RP4-635E18.7	0.17	0.17	lasso	5	0.09	1.3e-03	10.38	10.2	2.9e-24	0.03	0.05	0.88	FALSE
20	GTEx	Brain Cortex	RP4-635E18.7	0.17	0.05	lasso	4	0.07	6.4e-03	10.69	10.7	1.7e-26	0.00	0.02	0.89	FALSE
21	GTEx	Breast Mammary Tissue (Male)	RP5-1115A15.1	0.18	0.07	lasso	3	0.06	1.7e-02	6.04	-6.2	7.8e-10	-0.13	0.05	0.08	FALSE
22	GTEx	Cells EBV-transformed lymphocytes	H6PD	0.43	0.16	enet	48	0.10	3.5e-04	6.42	-6.7	2.0e-11	-0.15	0.34	0.05	FALSE
23	GTEx	Cells EBV-transformed lymphocytes	PGD	0.17	0.14	lasso	6	0.08	1.7e-03	9.85	11.3	9.1e-30	0.04	0.14	0.63	TRUE
24	GTEx	Cells Transformed fibroblasts	UBE4B	0.09	0.00	enet	21	0.00	1.4e-01	0.62	-6.3	3.9e-10	0.07	0.05	0.05	FALSE
25	GTEx	Cells Transformed fibroblasts	PGD	0.47	0.56	enet	15	0.55	7.5e-49	9.12	9.3	1.5e-20	0.09	1.00	0.00	FALSE
26	GTEx	Cells Transformed fibroblasts	NOL9	0.09	0.09	lasso	2	0.09	5.7e-07	-6.06	6.1	8.4e-10	0.03	0.01	0.99	TRUE
27	GTEx	Colon Transverse	DFFA	0.13	0.01	enet	7	0.01	9.0e-02	7.90	-7.9	2.2e-15	0.08	0.11	0.22	FALSE
28	GTEx	Esophagus Mucosa	RERE	0.13	0.16	lasso	3	0.16	7.2e-11	6.01	-6.0	1.9e-09	-0.10	1.00	0.00	FALSE
29	GTEx	Esophagus Mucosa	DFFA	0.11	0.00	lasso	2	0.00	1.6e-01	6.62	-7.4	1.0e-13	-0.01	0.07	0.47	FALSE
30	GTEx	Esophagus Mucosa	RP5-1115A15.1	0.06	0.06	lasso	4	0.05	3.0e-04	6.01	-6.7	1.7e-11	-0.09	0.30	0.25	TRUE
31	GTEx	Esophagus Muscularis	PGD	0.07	0.05	enet	9	0.05	4.8e-04	9.13	6.2	7.1e-10	0.11	0.14	0.83	FALSE
32	GTEx	Esophagus Muscularis	DFFA	0.12	0.00	enet	27	0.01	6.3e-02	4.81	-6.9	7.1e-12	0.04	0.20	0.08	FALSE
33	GTEx	Heart Left Ventricle	H6PD	0.15	0.12	lasso	1	0.11	1.5e-06	6.45	-6.5	1.2e-10	-0.14	0.80	0.03	FALSE
34	GTEx	Liver	PEX14	0.31	0.02	enet	10	-0.01	6.2e-01	6.28	-7.3	2.0e-13	-0.01	0.07	0.06	FALSE
35	GTEx	Lung	KIF1B	0.09	0.11	lasso	2	0.10	7.8e-08	9.85	9.8	9.3e-23	0.08	0.29	0.71	FALSE
36	GTEx	Lung	RERE	0.07	0.05	lasso	4	0.05	2.0e-04	6.32	-6.5	9.9e-11	-0.09	0.89	0.00	FALSE
37	GTEx	Lung	PEX14	0.17	0.12	enet	14	0.09	2.7e-07	6.88	-5.7	1.6e-08	-0.05	1.00	0.00	FALSE
38	GTEx	Lung	EXOSC10	0.11	0.07	lasso	4	0.05	1.2e-04	10.36	10.2	1.3e-24	0.04	0.10	0.89	FALSE
39	GTEx	Lung	RP5-1115A15.1	0.05	0.08	lasso	1	0.07	1.0e-05	6.08	-6.1	1.2e-09	-0.11	0.61	0.02	FALSE
40	GTEx	Muscle Skeletal	UBIAD1	0.09	0.00	enet	16	0.02	3.8e-03	8.37	-5.5	4.7e-08	0.03	0.05	0.69	FALSE
41	GTEx	Muscle Skeletal	PGD	0.14	0.15	enet	9	0.16	2.1e-15	9.12	9.2	3.9e-20	0.09	0.95	0.05	FALSE
42	GTEx	Muscle Skeletal	RP5-1115A15.1	0.09	0.07	enet	10	0.06	1.5e-06	6.01	-5.5	4.6e-08	-0.03	0.98	0.00	FALSE
43	GTEx	Nerve Tibial	MASP2	0.14	0.07	lasso	5	0.09	1.2e-06	7.02	6.7	1.6e-11	0.05	0.57	0.29	FALSE
44	GTEx	Skin Not Sun Exposed Suprapubic	NOL9	0.14	0.14	lasso	1	0.11	1.5e-06	-6.06	-6.1	1.4e-09	-0.03	0.01	0.99	FALSE
45	GTEx	Skin Not Sun Exposed Suprapubic	RP5-1115A15.1	0.08	0.04	enet	8	0.04	3.0e-03	6.56	-6.6	5.2e-11	-0.08	0.41	0.03	FALSE
46	GTEx	Skin Sun Exposed Lower leg	PGD	0.08	0.06	lasso	5	0.06	1.3e-05	-9.61	9.9	6.0e-23	0.05	0.01	0.99	FALSE
47	GTEx	Skin Sun Exposed Lower leg	NOL9	0.17	0.14	lasso	3	0.14	1.4e-11	-5.51	-5.6	2.6e-08	-0.01	0.02	0.98	FALSE
48	GTEx	Skin Sun Exposed Lower leg	RP5-1115A15.1	0.07	0.03	enet	13	0.03	1.5e-03	6.01	-5.3	1.4e-07	-0.08	0.60	0.03	FALSE
49	GTEx	Stomach	PGD	0.10	-0.01	enet	10	0.00	3.9e-01	9.13	7.8	7.8e-15	0.10	0.21	0.62	FALSE
50	GTEx	Stomach	RP4-635E18.7	0.13	0.06	enet	25	0.03	8.8e-03	9.69	7.2	7.5e-13	0.04	0.05	0.82	FALSE
51	GTEx	Thyroid	DFFA	0.06	0.07	enet	5	0.04	8.1e-04	-6.85	-8.1	5.7e-16	-0.01	0.30	0.14	FALSE
52	GTEx	Thyroid	RP4-635E18.7	0.07	0.02	lasso	2	0.01	5.5e-02	10.36	9.7	2.3e-22	0.00	0.03	0.82	FALSE
53	GTEx	Thyroid	RP5-1115A15.1	0.09	0.12	lasso	2	0.09	1.5e-07	6.08	-6.0	2.6e-09	-0.11	0.99	0.01	FALSE
54	GTEx	Whole Blood	RERE	0.19	0.15	lasso	4	0.13	2.7e-12	6.01	-6.0	2.1e-09	-0.10	1.00	0.00	FALSE
55	GTEx	Whole Blood	RBP7	0.06	0.00	enet	17	0.02	2.3e-03	0.92	-6.9	4.2e-12	-0.14	0.11	0.36	FALSE
56	GTEx	Whole Blood	MTOR	0.16	0.06	enet	18	0.07	5.1e-07	9.84	8.7	3.1e-18	0.01	0.70	0.29	FALSE
57	METSIM	Adipose	DFFA	0.05	0.03	enet	11	0.03	3.1e-05	-6.74	-6.6	3.2e-11	-0.05	1.00	0.00	FALSE
58	METSIM	Adipose	EXOSC10	0.05	0.06	lasso	1	0.05	3.5e-08	8.59	8.6	8.4e-18	0.05	0.04	0.96	FALSE
59	METSIM	Adipose	MTOR	0.04	0.02	bslmm	434	0.02	1.5e-04	10.70	10.3	5.8e-25	0.00	0.02	0.98	FALSE
60	METSIM	Adipose	PEX14	0.14	0.17	enet	13	0.16	3.3e-23	-6.74	-6.2	6.0e-10	-0.04	1.00	0.00	FALSE
61	METSIM	Adipose	RERE	0.08	0.12	lasso	17	0.13	1.8e-19	-3.73	-5.4	6.8e-08	-0.11	1.00	0.00	FALSE
62	NTR	Blood	H6PD	0.10	0.08	bslmm	435	0.08	3.1e-23	6.62	-7.3	2.8e-13	-0.18	1.00	0.00	FALSE
63	NTR	Blood	KIF1B	0.11	0.08	enet	11	0.09	3.7e-28	10.46	8.5	1.6e-17	-0.01	0.52	0.48	FALSE
64	NTR	Blood	PARK7	0.02	0.01	lasso	3	0.01	1.4e-05	8.18	8.4	3.7e-17	-0.09	0.04	0.96	FALSE
65	NTR	Blood	RBP7	0.02	0.02	lasso	2	0.02	4.7e-07	4.55	-5.3	9.9e-08	0.05	0.97	0.00	FALSE
66	ROSMAP	Brain Pre-frontal Cortex	RBP7	0.08	0.00	bslmm	301	0.01	4.9e-03	1.74	6.2	5.5e-10	-0.05	0.05	0.02	TRUE
67	ROSMAP	Brain Pre-frontal Cortex	EXOSC10	0.06	0.06	lasso	2	0.06	4.9e-08	10.65	10.6	3.5e-26	0.02	0.03	0.97	FALSE
68	ROSMAP	Brain Pre-frontal Cortex	NMNAT1	0.05	0.01	bslmm	301	0.01	5.6e-03	7.47	-5.4	6.3e-08	0.10	0.43	0.02	FALSE
69	ROSMAP	Brain Pre-frontal Cortex	MTOR	0.07	0.05	bslmm	423	0.04	2.0e-06	10.70	10.4	1.8e-25	0.01	0.01	0.99	FALSE
70	ROSMAP	Brain Pre-frontal Cortex	RP4-635E18.7	0.23	0.09	enet	24	0.24	3.8e-30	9.05	7.3	2.4e-13	0.02	0.04	0.96	FALSE
71	ROSMAP	Brain Pre-frontal Cortex	RP11-431K24.1	0.16	0.16	bslmm	384	0.17	3.1e-21	-7.07	-6.9	5.5e-12	-0.01	1.00	0.00	FALSE
72	YFS	Blood	KIF1B	0.30	0.26	enet	49	0.29	7.8e-97	10.46	7.8	4.6e-15	-0.01	0.35	0.65	FALSE
73	YFS	Blood	PARK7	0.08	0.11	lasso	6	0.11	4.4e-34	8.18	8.2	2.3e-16	-0.08	0.18	0.82	FALSE
74	YFS	Blood	PEX14	0.02	0.02	lasso	2	0.02	6.6e-07	6.15	-6.5	5.6e-11	-0.02	1.00	0.00	FALSE
75	YFS	Blood	RERE	0.09	0.15	lasso	4	0.16	5.7e-49	6.06	-5.3	1.0e-07	-0.11	1.00	0.00	FALSE
76	YFS	Blood	SPSB1	0.03	0.03	bslmm	425	0.03	1.5e-09	6.69	7.5	7.9e-14	-0.26	1.00	0.00	FALSE
77	YFS	Blood	UBE4B	0.03	0.01	bslmm	373	0.02	3.1e-06	5.78	-9.1	1.1e-19	0.05	0.98	0.00	TRUE
78	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	APITD1	0.07	0.01	enet	12	0.04	4.6e-04	-0.74	8.3	1.1e-16	0.00	0.02	0.12	FALSE
79	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	H6PD	0.10	0.04	enet	13	0.05	2.2e-05	6.42	-5.4	6.0e-08	-0.11	0.09	0.07	FALSE
80	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PGD	0.04	0.02	blup	52	0.03	2.6e-03	9.10	8.6	8.6e-18	0.11	0.10	0.11	FALSE
81	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	VAMP3	0.07	0.04	lasso	3	0.06	3.7e-06	5.56	-5.4	7.8e-08	0.01	0.29	0.37	FALSE
82	The Cancer Genome Atlas	Breast Invasive Carcinoma	ERRFI1	0.01	0.01	blup	27	0.00	4.3e-02	8.18	-8.3	1.1e-16	0.08	0.01	0.83	FALSE
83	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIF1B	0.05	0.01	blup	108	0.01	9.4e-04	9.10	8.0	9.4e-16	0.08	0.03	0.92	FALSE
84	The Cancer Genome Atlas	Breast Invasive Carcinoma	PARK7	0.02	0.01	blup	36	0.02	2.1e-04	8.30	5.8	7.5e-09	-0.09	0.01	0.92	FALSE
85	The Cancer Genome Atlas	Breast Invasive Carcinoma	PGD	0.06	0.07	lasso	5	0.07	9.8e-15	9.14	7.6	3.9e-14	0.11	0.71	0.29	FALSE
86	The Cancer Genome Atlas	Colon Adenocarcinoma	VAMP3	0.12	0.02	blup	58	0.06	3.0e-04	-2.77	-6.9	6.7e-12	0.06	0.01	0.82	FALSE
87	The Cancer Genome Atlas	Esophageal Carcinoma	RERE	0.10	0.07	blup	154	0.06	5.2e-03	4.46	-5.6	2.3e-08	-0.08	0.08	0.08	FALSE
88	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	H6PD	0.10	0.11	lasso	1	0.11	3.7e-12	6.62	-6.6	3.5e-11	-0.14	1.00	0.00	FALSE
89	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PARK7	0.03	0.03	enet	3	0.02	1.3e-03	8.21	8.5	2.2e-17	-0.07	0.00	0.94	TRUE
90	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PGD	0.04	0.03	lasso	4	0.02	2.1e-03	7.40	7.9	2.2e-15	0.11	0.06	0.40	FALSE
91	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MTOR	0.02	0.02	blup	54	0.02	5.4e-03	10.03	10.2	2.3e-24	0.00	0.08	0.62	FALSE
92	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	VAMP3	0.08	0.02	blup	58	0.02	2.8e-02	-1.92	-5.9	3.2e-09	0.06	0.02	0.37	FALSE
93	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTOR	0.03	0.01	blup	54	0.02	5.9e-03	9.96	9.7	3.4e-22	0.00	0.03	0.71	FALSE
94	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MASP2	0.05	0.03	blup	30	0.04	6.0e-03	2.87	-8.8	2.1e-18	-0.03	0.02	0.58	FALSE
95	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PEX14	0.08	0.01	enet	8	0.05	3.1e-03	-6.54	-7.0	2.2e-12	0.01	0.04	0.32	FALSE
96	The Cancer Genome Atlas	Lung Adenocarcinoma	PARK7	0.03	0.03	lasso	1	0.02	5.0e-03	8.18	8.2	2.9e-16	-0.08	0.01	0.80	FALSE
97	The Cancer Genome Atlas	Lung Adenocarcinoma	PGD	0.04	0.06	lasso	9	0.06	3.9e-07	9.09	9.2	4.7e-20	0.09	0.71	0.28	FALSE
98	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	H6PD	0.10	0.11	lasso	2	0.11	2.5e-12	6.62	-6.4	1.8e-10	-0.16	1.00	0.00	FALSE
99	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PARK7	0.04	0.03	blup	36	0.03	4.9e-04	8.30	6.5	5.6e-11	-0.10	0.01	0.96	FALSE
100	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PGD	0.03	0.03	lasso	2	0.01	1.4e-02	6.34	6.3	2.4e-10	0.07	0.09	0.04	FALSE
101	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PGD	0.07	0.00	enet	5	0.04	1.0e-02	7.40	8.0	1.0e-15	0.12	0.04	0.05	FALSE
102	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	H6PD	0.31	0.06	blup	64	0.14	3.8e-06	7.73	-14.2	7.4e-46	0.27	0.04	0.41	TRUE
103	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PARK7	0.22	0.00	blup	35	0.03	2.2e-02	8.30	6.2	5.5e-10	-0.04	0.00	0.52	FALSE
104	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PGD	0.09	0.02	blup	52	0.05	6.0e-03	6.34	9.7	2.9e-22	0.08	0.03	0.13	FALSE
105	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PLEKHG5	0.14	0.08	lasso	2	0.07	9.3e-04	-5.60	5.2	2.4e-07	-0.01	0.02	0.84	FALSE
106	The Cancer Genome Atlas	Prostate Adenocarcinoma	APITD1	0.07	0.11	lasso	4	0.10	2.0e-10	6.08	5.8	7.7e-09	0.07	1.00	0.00	FALSE
107	The Cancer Genome Atlas	Prostate Adenocarcinoma	CAMTA1	0.11	0.03	lasso	7	0.02	2.0e-03	4.14	5.2	2.2e-07	0.02	0.52	0.02	TRUE
108	The Cancer Genome Atlas	Prostate Adenocarcinoma	PEX14	0.07	0.00	enet	19	0.01	5.2e-02	7.90	-6.9	4.6e-12	0.08	0.01	0.89	TRUE
109	The Cancer Genome Atlas	Soft Tissue Sarcoma	VAMP3	0.11	0.07	lasso	4	0.05	7.5e-04	7.49	-7.5	9.2e-14	0.09	0.00	0.98	FALSE
110	The Cancer Genome Atlas	Stomach Adenocarcinoma	H6PD	0.08	0.07	lasso	4	0.05	2.5e-04	6.42	-6.5	7.5e-11	-0.17	0.41	0.07	FALSE
111	The Cancer Genome Atlas	Stomach Adenocarcinoma	PGD	0.05	0.04	blup	51	0.03	2.8e-03	9.12	8.4	4.5e-17	0.08	0.15	0.24	FALSE
112	The Cancer Genome Atlas	Thyroid Carcinoma	APITD1	0.12	0.13	lasso	3	0.11	5.9e-11	6.08	6.0	1.6e-09	0.08	1.00	0.00	FALSE
113	The Cancer Genome Atlas	Thyroid Carcinoma	PGD	0.06	0.05	enet	10	0.03	7.7e-04	9.12	9.2	4.8e-20	0.09	0.58	0.24	FALSE