[Hub]/) : Traits : Height :

chr7:98,244,565-102,866,033

Best TWAS P=1.67e-21 · Best GWAS P=7.09e-22 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CPSF4 0.06 0.06 blup 313 0.07 6.6e-09 8.49 5.8 4.9e-09 0.08 0.06 0.94 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100289187 0.08 0.02 enet 14 0.03 4.5e-05 7.43 -6.3 2.2e-10 -0.17 0.09 0.91 TRUE
3 GTEx Adipose Visceral Omentum GS1-259H13.2 0.23 0.12 lasso 1 0.09 1.8e-05 7.55 -7.5 4.2e-14 -0.24 0.86 0.04 FALSE
4 GTEx Adrenal Gland STAG3L5P-PVRIG2P-PILRB 0.32 0.25 enet 43 0.20 7.0e-08 -3.32 -6.3 2.6e-10 -0.09 0.99 0.00 TRUE
5 GTEx Artery Aorta ACHE 0.35 0.31 enet 35 0.32 1.9e-18 8.15 7.5 5.3e-14 0.04 0.01 0.99 FALSE
6 GTEx Artery Aorta SRRT 0.11 0.09 enet 20 0.09 1.4e-05 8.10 6.1 1.4e-09 0.00 0.01 0.98 FALSE
7 GTEx Artery Tibial ACHE 0.10 0.09 lasso 5 0.08 9.2e-07 8.10 8.1 5.3e-16 0.05 0.00 1.00 FALSE
8 GTEx Brain Cerebellar Hemisphere UFSP1 0.42 0.03 enet 7 0.05 1.9e-02 -6.24 -6.2 7.6e-10 -0.03 0.44 0.03 FALSE
9 GTEx Breast Mammary Tissue AP1S1 0.18 0.14 lasso 4 0.12 1.5e-06 -4.24 -5.8 6.4e-09 -0.01 0.82 0.05 FALSE
10 GTEx Breast Mammary Tissue (Female) PRKRIP1 0.14 -0.01 lasso 4 0.00 3.4e-01 -5.03 6.6 4.1e-11 0.05 0.03 0.06 TRUE
11 GTEx Breast Mammary Tissue (Female) ATP5J2 0.13 0.04 enet 10 0.10 5.5e-04 -7.61 -8.7 3.3e-18 -0.01 0.06 0.20 TRUE
12 GTEx Cells EBV-transformed lymphocytes RP11-163E9.2 0.25 0.23 enet 9 0.23 3.4e-08 4.80 -5.1 3.1e-07 -0.01 0.52 0.06 FALSE
13 GTEx Cells Transformed fibroblasts CPSF4 0.08 0.03 lasso 4 0.03 1.8e-03 7.43 7.6 2.7e-14 0.24 0.34 0.19 FALSE
14 GTEx Cells Transformed fibroblasts POLR2J3 0.32 0.08 lasso 7 0.11 8.6e-09 4.02 5.4 7.0e-08 0.03 0.96 0.00 FALSE
15 GTEx Cells Transformed fibroblasts RP11-514P8.8 0.31 0.12 lasso 7 0.14 1.0e-10 4.02 5.2 2.6e-07 0.00 1.00 0.00 TRUE
16 GTEx Colon Sigmoid CLDN15 0.29 0.00 lasso 4 0.00 4.5e-01 -6.19 -5.4 5.2e-08 -0.05 0.39 0.03 TRUE
17 GTEx Esophagus Mucosa ACHE 0.08 0.03 lasso 9 0.03 2.2e-03 5.48 7.2 5.1e-13 0.04 0.02 0.93 FALSE
18 GTEx Esophagus Mucosa GS1-259H13.2 0.07 0.07 lasso 3 0.05 1.7e-04 7.53 -7.7 1.2e-14 -0.24 0.46 0.34 TRUE
19 GTEx Heart Atrial Appendage ACHE 0.19 0.19 lasso 2 0.18 2.6e-08 7.61 7.6 2.9e-14 0.04 0.01 0.99 FALSE
20 GTEx Heart Atrial Appendage SRRT 0.14 0.01 enet 10 0.02 4.5e-02 7.61 8.2 3.7e-16 0.03 0.01 0.88 FALSE
21 GTEx Heart Left Ventricle CLDN15 0.22 0.02 lasso 7 0.03 1.3e-02 -4.54 -5.8 5.1e-09 0.02 0.98 0.00 TRUE
22 GTEx Lung ZKSCAN5 0.09 0.05 lasso 2 0.03 2.7e-03 7.43 -7.0 2.2e-12 -0.22 0.37 0.16 FALSE
23 GTEx Lung GS1-259H13.2 0.09 0.07 lasso 4 0.05 8.4e-05 7.53 -7.5 8.4e-14 -0.25 0.79 0.06 FALSE
24 GTEx Muscle Skeletal TRIP6 0.08 0.07 lasso 4 0.07 5.3e-07 7.04 6.4 1.6e-10 0.02 0.39 0.57 FALSE
25 GTEx Muscle Skeletal POLR2J3 0.35 0.12 enet 31 0.16 5.6e-16 4.02 5.3 9.0e-08 0.00 1.00 0.00 TRUE
26 GTEx Nerve Tibial ACHE 0.28 0.23 lasso 7 0.22 6.1e-16 7.61 7.4 1.1e-13 0.04 0.01 0.99 FALSE
27 GTEx Nerve Tibial SRRT 0.13 0.12 lasso 4 0.11 3.7e-08 7.43 7.5 5.2e-14 0.04 0.01 0.99 FALSE
28 GTEx Nerve Tibial ZKSCAN5 0.12 0.04 lasso 4 0.02 1.4e-02 3.80 -5.9 3.7e-09 -0.09 0.09 0.04 TRUE
29 GTEx Nerve Tibial GS1-259H13.2 0.15 0.10 lasso 4 0.09 3.4e-07 7.53 -7.5 8.4e-14 -0.24 1.00 0.00 FALSE
30 GTEx Prostate RP11-163E9.2 0.33 -0.01 lasso 10 0.00 2.5e-01 4.84 -5.4 5.4e-08 -0.04 0.03 0.25 FALSE
31 GTEx Skin Not Sun Exposed Suprapubic TRIP6 0.11 0.02 lasso 6 0.01 1.3e-01 -3.09 5.4 8.5e-08 0.01 0.08 0.27 FALSE
32 GTEx Skin Not Sun Exposed Suprapubic CLDN15 0.33 0.28 lasso 6 0.30 1.1e-16 -4.55 -5.5 5.1e-08 0.03 1.00 0.00 FALSE
33 GTEx Skin Sun Exposed Lower leg ACHE 0.07 0.10 lasso 1 0.09 3.5e-08 7.61 7.6 2.8e-14 0.04 0.04 0.96 FALSE
34 GTEx Skin Sun Exposed Lower leg POLR2J3 0.17 0.06 enet 15 0.08 5.1e-07 4.02 5.8 5.6e-09 -0.03 0.62 0.02 FALSE
35 GTEx Skin Sun Exposed Lower leg RASA4B 0.12 0.00 enet 20 0.04 2.2e-04 4.19 5.6 2.7e-08 0.02 0.03 0.05 TRUE
36 GTEx Skin Sun Exposed Lower leg RP11-514P8.8 0.17 0.08 enet 14 0.11 2.2e-09 4.02 5.8 6.8e-09 -0.02 0.92 0.00 TRUE
37 GTEx Spleen GIGYF1 0.22 0.00 enet 19 0.10 1.3e-03 -5.19 -5.7 1.3e-08 -0.38 0.13 0.09 FALSE
38 GTEx Testis ATP5J2 0.21 0.13 lasso 7 0.19 7.5e-09 3.74 -5.9 3.9e-09 -0.04 0.62 0.36 TRUE
39 GTEx Thyroid ACHE 0.19 0.10 enet 33 0.14 1.5e-10 8.10 9.1 1.5e-19 0.00 0.01 0.99 FALSE
40 GTEx Whole Blood ORAI2 0.13 0.13 enet 7 0.12 2.1e-11 4.84 -5.3 1.4e-07 -0.02 0.96 0.04 FALSE
41 METSIM Adipose ARPC1A 0.02 0.02 blup 308 0.02 1.6e-03 3.34 5.4 6.3e-08 0.00 0.16 0.73 TRUE
42 METSIM Adipose GS1-259H13.2 0.04 0.03 lasso 3 0.02 1.4e-03 7.52 -7.5 5.0e-14 -0.25 0.56 0.35 FALSE
43 METSIM Adipose MBLAC1 0.04 0.00 bslmm 284 0.01 1.8e-02 -0.17 5.8 5.8e-09 0.06 0.05 0.04 TRUE
44 METSIM Adipose PRKRIP1 0.12 0.00 blup 272 0.08 1.1e-11 2.88 6.2 7.4e-10 -0.01 0.81 0.17 FALSE
45 NTR Blood ORAI2 0.05 0.03 bslmm 256 0.03 2.0e-11 4.83 -6.2 6.8e-10 -0.01 0.94 0.06 TRUE
46 ROSMAP Brain Pre-frontal Cortex SRRT 0.05 0.02 bslmm 331 0.02 1.1e-03 8.10 9.5 1.7e-21 0.12 0.01 0.98 TRUE
47 ROSMAP Brain Pre-frontal Cortex ZKSCAN1 0.05 0.01 blup 265 0.03 6.1e-05 -2.46 -5.2 2.1e-07 -0.31 0.30 0.05 TRUE
48 ROSMAP Brain Pre-frontal Cortex SLC12A9 0.07 0.05 lasso 4 0.07 7.6e-10 -2.92 5.3 1.3e-07 -0.01 0.88 0.12 FALSE
49 ROSMAP Brain Pre-frontal Cortex GS1-259H13.2 0.07 0.05 bslmm 305 0.06 6.9e-08 7.79 -7.1 1.2e-12 -0.17 0.63 0.37 TRUE
50 YFS Blood ORAI2 0.17 0.13 lasso 13 0.18 4.2e-56 4.83 -5.4 6.3e-08 -0.03 0.94 0.06 FALSE
51 YFS Blood PRKRIP1 0.11 0.09 enet 25 0.10 1.2e-30 4.84 5.2 2.5e-07 0.00 0.94 0.06 FALSE
52 YFS Blood TRIP6 0.08 0.10 lasso 6 0.11 6.7e-35 7.61 -7.2 8.0e-13 -0.06 0.02 0.98 FALSE
53 The Cancer Genome Atlas Bladder Urothelial Carcinoma CUX1 0.10 0.03 blup 114 0.02 1.5e-02 2.99 -5.7 1.2e-08 0.05 0.22 0.05 TRUE
54 The Cancer Genome Atlas Bladder Urothelial Carcinoma PILRA 0.05 0.01 blup 32 0.02 5.5e-03 -3.36 -5.2 1.7e-07 -0.33 0.02 0.58 FALSE
55 The Cancer Genome Atlas Breast Invasive Carcinoma ACHE 0.03 0.01 blup 56 0.01 1.8e-03 7.23 8.4 3.8e-17 0.05 0.01 0.76 FALSE
56 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma UFSP1 0.09 0.03 blup 53 0.05 1.2e-03 6.54 -9.1 1.1e-19 -0.03 0.02 0.59 FALSE
57 The Cancer Genome Atlas Glioblastoma Multiforme EPHB4 0.16 0.11 enet 7 0.07 3.8e-03 8.10 -7.6 2.4e-14 -0.06 0.00 0.91 FALSE
58 The Cancer Genome Atlas Brain Lower Grade Glioma AP1S1 0.07 0.02 enet 12 0.06 1.0e-07 -4.21 -5.2 1.6e-07 0.00 0.34 0.65 FALSE
59 The Cancer Genome Atlas Brain Lower Grade Glioma ZKSCAN5 0.03 0.04 lasso 2 0.03 1.0e-04 8.48 8.5 2.3e-17 0.17 0.01 0.99 TRUE
60 The Cancer Genome Atlas Pancreatic Adenocarcinoma C7orf52 0.23 0.10 blup 54 0.12 7.0e-06 -4.21 6.6 3.2e-11 0.01 0.28 0.63 TRUE
61 The Cancer Genome Atlas Prostate Adenocarcinoma FIS1 0.03 0.02 blup 42 0.02 1.8e-03 -4.54 5.2 2.3e-07 -0.02 0.01 0.49 FALSE
62 The Cancer Genome Atlas Prostate Adenocarcinoma ZKSCAN5 0.03 0.03 enet 8 0.03 5.4e-04 8.53 7.0 2.5e-12 0.16 0.01 0.84 TRUE
63 The Cancer Genome Atlas Thyroid Carcinoma ACHE 0.04 0.04 lasso 2 0.03 3.0e-04 7.43 7.5 8.6e-14 0.04 0.01 0.98 FALSE
64 The Cancer Genome Atlas Thyroid Carcinoma C7orf52 0.09 0.08 enet 16 0.12 1.8e-11 -6.57 5.7 1.2e-08 0.01 0.70 0.30 FALSE