TWAS hub - TRIP6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0480	0.0220	4.2e-03	0.005	0.010	0.003	0.008	0.002	7.0e-02	1.9e-02	1.1e-01	3.2e-02	1.8e-01
2	GTEx	Artery Aorta	0.1020	0.0410	1.1e-03	0.050	NA	0.039	NA	0.025	9.0e-04	NA	3.3e-03	NA	1.5e-02
3	GTEx	Esophagus Mucosa	0.1490	0.0490	3.4e-05	0.156	NA	0.139	NA	0.147	1.3e-10	NA	1.4e-09	NA	4.7e-10
4	GTEx	Heart Atrial Appendage	0.3390	0.0920	2.5e-04	0.045	NA	0.063	NA	0.078	4.2e-03	NA	8.9e-04	NA	2.3e-04
5	GTEx	Lung	0.0638	0.0278	1.0e-03	0.035	NA	0.038	NA	0.032	9.9e-04	NA	6.9e-04	NA	1.7e-03
6	GTEx	Muscle Skeletal	0.0786	0.0312	4.6e-04	0.073	NA	0.065	NA	0.065	1.1e-07	NA	5.5e-07	NA	5.3e-07
7	GTEx	Nerve Tibial	0.1050	0.0426	9.4e-04	0.077	NA	0.109	NA	0.087	4.2e-06	NA	3.9e-08	NA	1.0e-06
8	GTEx	Skin Not Sun Exposed Suprapubic	0.1090	0.0540	7.9e-03	0.016	NA	0.002	NA	0.007	4.1e-02	NA	2.4e-01	NA	1.3e-01
9	YFS	Blood	0.0821	0.0190	0.0e+00	0.105	0.098	0.110	0.106	0.113	1.8e-32	2.2e-30	5.2e-34	6.5e-33	6.7e-35
10	TCGA	Bladder Urothelial Carcinoma	0.1180	0.0460	2.9e-06	0.031	0.075	0.078	NA	0.072	1.0e-03	6.1e-07	3.9e-07	NA	1.1e-06
11	TCGA	Breast Invasive Carcinoma	0.0282	0.0142	6.4e-05	0.026	0.023	0.019	NA	0.024	3.8e-06	1.5e-05	5.5e-05	NA	6.8e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Pulse rate, automated reading	48.0	155.0	338.6	10.8	13.3	-2.8	12.4	11.5	13.3	13.9	16.0	-18.4	-12.0	-3.0
Pulse rate	28.5	48.0	114.5	6.4	7.1	-2.1	6.8	5.9	7.1	7.3	8.6	-10.7	-7.3	-2.2
Diastolic blood pressure, automated reading	7.1	22.1	39.0	6.0	5.5	-0.4	4.3	4.2	6.2	4.5	5.7	-6.2	-3.1	-0.4
Irritable Bowel Disease (IBD)	4.7	11.2	20.7	-0.6	3.7	-1.3	4.4	3.8	1.9	4.5	4.0	-4.4	-3.6	-1.1
Average weekly fortified wine intake	4.5	5.2	11.6	-1.3	-2.9	-0.3	-3.4	-2.6	-2.1	-2.7	-2.5	3.0	1.2	-0.5
Ulcerative Colitis (UC)	4.4	8.2	15.8	-0.4	3.6	0.7	3.8	3.9	1.9	3.7	4.0	-3.2	-1.4	0.8
Ulcerative Colitis	4.4	6.4	13.1	-0.5	3.0	0.1	3.0	3.5	1.9	3.6	3.6	-2.9	-1.4	0.4
Blood Red Count	4.1	39.2	136.9	0.8	2.3	-11.7	3.6	-5.7	-5.2	-1.0	-4.1	-1.1	-8.2	-11.3
Relative age voice broke	3.9	6.0	10.4	1.1	3.2	2.3	2.8	3.2	2.4	3.1	2.7	-1.4	0.8	2.3
Pack years adult smoking proportion	3.7	5.7	13.3	-2.0	-2.3	-2.1	-2.8	-2.5	-3.3	-1.6	-3.6	1.4	-1.0	-2.2
Hypothyroidism/myxoedema (self-reported)	3.7	7.2	18.6	-3.5	-2.1	0.6	-2.3	-1.8	-4.3	-3.1	-2.8	3.6	2.0	0.2
Family relationship satisfaction	3.6	4.5	9.2	-1.2	-2.1	-3.0	-2.3	-2.4	-1.5	-2.0	-1.2	-0.3	-2.7	-2.9
Heel T-Score	3.5	28.1	68.4	-8.3	-6.5	-2.8	-4.8	-5.2	-6.5	-4.4	-6.4	5.5	0.9	-2.7
Hair/balding pattern: Pattern 3	3.4	5.0	11.1	-1.5	-2.9	-0.7	-2.5	-2.5	-2.6	-1.6	-3.1	3.3	1.2	-0.7
Hair/balding pattern: Pattern 2	3.3	4.2	9.7	0.0	1.8	2.2	1.8	2.8	2.7	1.4	3.1	-1.5	0.8	2.3
Schizophrenia (2014)	3.2	7.0	21.2	0.7	3.1	-0.5	2.4	3.3	2.5	4.6	3.3	-3.0	-1.7	-0.3
Stomach or abdominal pain in last month	3.1	3.8	6.9	-1.7	-2.2	-0.4	-2.3	-2.1	-2.3	-2.4	-2.3	2.6	1.1	-0.6
Supplements: Glucosamine	3.1	4.1	10.3	-2.4	-2.3	0.9	-2.8	-1.2	-1.2	-1.7	-1.9	3.2	2.2	0.7
Medication: Ibuprofen	3.1	3.8	7.2	-2.5	-1.9	-1.9	-1.9	-1.9	-2.0	-2.1	-2.7	1.5	-0.5	-1.8
Pack years of smoking	3.1	4.5	11.1	-1.5	-2.1	-1.8	-2.6	-2.1	-3.1	-1.1	-3.3	1.3	-0.9	-1.9
Crohns Disease (2012)	2.9	4.7	16.3	-1.4	0.4	-3.6	1.1	0.2	-0.6	1.2	0.5	-2.4	-4.0	-3.4
Fasting Glucose	2.9	3.5	12.7	-1.0	-0.9	2.5	-1.1	-0.0	-0.2	-1.3	-0.8	2.8	3.6	2.5
Townsend deprivation index at recruitment	2.9	4.0	12.5	0.2	0.1	-3.5	-0.2	-1.7	-1.2	-0.4	-0.8	-1.9	-3.5	-3.3
Serious illness, injury or assault of a close relative in last 2 years	2.9	3.4	6.9	-2.5	-2.2	-1.0	-0.9	-1.9	-2.4	-1.9	-2.6	1.7	0.2	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.9	3.4	7.3	1.6	2.0	-0.4	2.3	1.6	1.6	2.4	2.7	-2.3	-1.5	-0.4
Heart disease (siblings)	2.8	3.4	6.3	2.2	2.2	0.6	1.8	2.0	2.4	2.2	2.5	-1.8	-0.3	0.5
Crohns Disease (2017)	2.7	6.0	12.1	-0.6	2.1	-1.9	2.6	2.4	1.1	3.2	2.5	-3.5	-3.5	-1.8
Type 2 Diabetes (T2D) (2018)	2.7	5.0	10.5	-2.9	-1.9	0.4	-2.7	-1.2	-2.5	-2.9	-2.0	3.2	2.1	0.4
Diabetes (self-reported)	2.7	4.1	8.8	-3.0	-1.7	-0.7	-2.4	-1.1	-2.8	-2.9	-1.8	2.2	0.8	-0.7
Smoking status: Previous	2.7	4.1	8.5	-2.0	-1.8	1.6	-2.1	-0.8	-0.6	-2.3	-2.2	2.9	2.9	1.7
Hypothyroidism (self reported)	2.6	5.9	14.1	-2.7	-2.1	0.5	-2.5	-2.0	-3.8	-2.7	-2.3	3.5	1.9	0.1
Medication: Omeprazole (e.g. Zanprol)	2.6	3.1	6.3	-0.8	-2.5	-0.6	-2.2	-2.3	-1.2	-2.0	-2.2	2.3	0.8	-0.6
Breast Cancer	2.5	5.9	12.0	-2.2	-3.1	-1.7	-2.6	-3.0	-3.5	-2.8	-2.6	1.4	-0.7	-1.8
Supplements: Zinc	2.5	2.7	5.7	-2.4	-1.9	-0.9	-1.2	-1.6	-1.9	-1.5	-1.8	2.4	0.5	-0.8
Illnesses of siblings	2.5	3.5	6.8	-1.4	-2.0	-2.0	-1.4	-2.6	-2.4	-1.5	-2.5	1.7	-0.6	-1.8
Bipolar Disorder or Schizophrenia	2.4	6.0	13.9	0.6	2.2	-2.4	1.1	2.4	1.3	3.7	2.4	-3.3	-3.3	-2.0
Hand grip strength (right)	2.4	6.6	20.2	0.7	0.9	-2.6	2.3	0.6	2.0	1.7	2.4	-4.5	-4.3	-2.7
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.1	8.1	-2.8	-1.6	-1.4	-1.4	-1.5	-1.7	-2.1	-2.4	1.6	-0.0	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	2.4	2.6	4.2	-2.0	-1.6	-1.6	-1.6	-1.7	-1.5	-1.5	-1.6	2.1	0.0	-1.5
Ever smoked	2.4	4.2	9.4	-1.4	-1.3	1.6	-2.1	-0.9	-1.4	-2.8	-2.0	3.1	2.9	1.6
Hair Pigment	2.3	64.8	237.2	-1.4	-1.0	13.1	-1.6	1.2	-1.3	-5.8	-0.4	9.8	15.4	12.9
Medication: Levothyroxine sodium	2.3	3.8	10.8	-2.6	-1.6	0.1	-1.4	-1.3	-3.3	-1.9	-2.7	2.5	1.0	-0.2
Past tobacco smoking	2.3	4.1	9.4	1.8	1.7	-1.7	2.0	1.0	0.7	2.4	2.0	-3.1	-2.9	-1.7
Depression (self-reported)	2.3	2.7	5.6	-0.3	-1.9	-1.9	-2.1	-1.8	-1.9	-1.4	-2.4	-0.0	-1.5	-1.5
Medication: Omeprazole	2.3	2.7	6.2	-1.2	-2.5	-0.9	-1.9	-2.1	-1.2	-1.5	-2.1	2.0	0.4	-0.9
Mean Putamen Volume	2.2	2.5	4.2	-1.9	-1.9	-1.6	-1.6	-2.0	-1.3	-2.0	-0.7	1.8	0.1	-1.4
LDL Cholesterol	2.2	3.4	6.5	2.3	1.4	-0.2	1.5	1.7	2.5	2.5	2.2	-2.5	-1.2	0.1
Medication: Metformin	2.2	3.0	9.9	-3.2	0.0	1.6	0.1	0.8	-1.3	-1.1	0.2	2.5	2.8	1.7
Suffer from ‘nerves’	2.2	3.4	8.1	0.7	2.0	-0.6	2.8	1.5	2.2	2.3	2.0	-2.3	-1.6	-0.3
Medication: Atorvastatin	2.2	2.7	6.3	1.9	1.1	-0.4	1.0	1.5	1.9	2.1	2.0	-2.5	-1.7	-0.5
Schizophrenia (2018)	2.1	4.4	11.5	0.5	2.2	-1.7	1.4	2.1	2.0	3.4	2.3	-2.7	-2.3	-1.2
Heart attack	2.1	2.6	4.5	-1.7	-2.1	-0.4	-1.8	-1.8	-2.0	-1.9	-1.8	1.8	0.6	-0.7
Lung cancer (father)	2.1	2.5	4.0	0.9	2.0	1.5	1.7	2.0	1.9	1.9	1.5	-0.8	0.7	1.6
Forced vital capacity (FVC), Best measure	2.1	7.6	21.2	2.2	3.2	-0.5	2.8	2.2	3.0	1.7	3.8	-4.6	-3.0	-0.3
Loneliness, isolation	2.1	2.9	9.9	-0.3	-0.1	-2.8	0.2	-1.3	-1.0	-0.5	-1.1	-1.7	-3.2	-2.7
Cholesterol lowering medication	2.1	3.1	6.5	1.0	2.0	0.6	1.3	2.5	1.9	2.5	2.5	-1.8	-0.6	0.5
Blood Platelet Count	2.0	23.3	39.7	6.0	5.3	5.7	3.3	6.3	4.7	4.0	5.3	-3.3	1.5	5.4
Forced vital capacity (FVC)	2.0	7.8	22.2	1.9	3.1	-0.7	2.9	2.2	2.9	2.1	3.7	-4.7	-3.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.2	7.7	1.5	1.6	2.7	1.5	2.1	2.7	0.8	2.8	-1.6	1.2	2.6
Supplements: Calcium	2.0	2.2	5.8	-1.5	-1.6	-1.2	-0.8	-1.9	-1.2	-1.8	-2.4	0.8	-0.4	-1.3
Frequency of depressed mood in last 2 weeks	1.9	2.6	7.0	-0.8	-1.2	-2.6	-0.2	-1.7	-1.2	-0.9	-1.0	-1.1	-2.6	-2.4
High blood pressure (mother)	1.9	2.6	5.9	0.6	1.4	2.4	0.7	2.1	1.9	0.9	1.6	0.1	1.9	2.4
Diabetes diagnosed by doctor	1.9	3.0	7.2	-2.7	-1.1	0.4	-2.2	-0.3	-2.2	-2.0	-1.3	2.6	1.7	0.5
Heart attack/myocardial infarction (self-reported)	1.9	2.5	4.8	-1.6	-2.2	-0.6	-1.8	-1.8	-1.8	-1.9	-1.5	1.7	0.5	-0.8
HDL Cholesterol	1.8	3.0	8.6	2.9	1.7	1.3	0.8	1.8	2.5	1.4	1.4	-2.2	-0.2	1.3
Hand grip strength (left)	1.8	4.6	14.6	0.5	0.7	-2.3	1.4	0.4	2.0	1.4	2.0	-3.8	-3.6	-2.4
Medication for cholesterol, blood pressure or diabetes	1.8	2.9	6.9	-0.4	-1.7	-2.6	-1.0	-2.1	-1.0	-1.5	-2.1	-0.3	-1.9	-2.5
Age at first live birth	1.8	3.1	7.8	-0.8	-2.5	1.2	-1.4	-1.7	-1.5	-2.8	-0.8	2.2	2.0	1.1
Mean time to correctly identify matches	1.8	3.5	6.9	0.9	2.4	-0.5	1.4	2.2	1.6	2.6	2.4	-2.5	-1.9	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.8	8.4	1.2	1.9	-0.9	2.5	1.4	1.2	2.9	2.1	-2.8	-2.3	-0.7
Systolic Blood Pressure	1.7	8.7	29.5	1.8	0.1	4.9	-1.3	1.2	1.2	-1.2	0.1	2.6	5.4	5.1
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.7	9.6	-1.8	-0.5	-2.5	0.5	-0.8	-0.1	0.2	0.2	-1.6	-3.1	-2.6
Father’s age at death	1.7	2.3	7.8	1.3	-0.2	2.2	-0.3	0.2	0.6	0.2	-0.3	2.3	2.8	2.3
Tense / ‘highly strung’	1.7	2.8	8.0	-1.8	-1.5	-2.4	-0.0	-0.9	-0.9	0.6	-0.7	-1.5	-2.8	-2.6
Exposure to tobacco smoke outside home	1.7	2.2	3.9	1.2	1.9	1.7	1.3	1.6	1.4	2.0	1.3	0.3	1.4	1.7
Friendships satisfaction	1.7	2.1	6.3	-1.1	-0.6	-2.3	0.0	-0.7	-1.2	-0.6	-0.2	-1.4	-2.5	-2.3
Pulse wave reflection index	1.6	2.0	6.4	-1.6	-1.2	-0.4	-0.6	-1.6	-2.5	-1.6	-1.5	1.8	0.6	-0.4
Vascular/heart problems diagnosed by doctor	1.6	4.5	7.7	-2.1	-2.3	-2.3	-1.2	-2.4	-2.6	-2.1	-2.8	0.6	-1.5	-2.3
Alzheimer’s Disease (in mother)	1.5	1.7	3.7	0.3	-1.5	-1.8	-1.4	-1.9	-0.5	-1.3	-1.1	0.5	-0.8	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	4.5	-1.6	-1.2	-2.1	-1.1	-1.2	-1.5	-1.3	-1.4	-0.5	-2.0	-2.0
Medication: Aspirin	1.5	1.9	6.0	-1.0	-0.3	1.7	-0.9	-0.0	-1.3	-1.4	-0.7	1.9	2.4	1.7
Average weekly red wine intake	1.5	2.1	7.1	-0.8	-1.0	1.8	-1.0	-0.2	-1.0	-1.2	-0.8	2.1	2.7	1.8
Alzheimer’s Disease (including proxy)	1.4	2.1	4.9	-0.5	-1.6	-2.1	-1.5	-1.9	-1.1	-1.1	-0.9	0.8	-1.0	-2.2
Reaction Time	1.4	2.7	4.9	-0.2	1.9	-0.8	1.2	1.6	1.6	2.1	2.0	-2.2	-2.0	-0.9
Diabetes (mother)	1.4	1.8	6.0	0.8	0.8	2.1	-0.8	0.7	0.3	-0.9	-0.6	1.3	2.4	2.0
Severe depression (siblings)	1.4	1.5	5.1	-1.1	-0.5	-2.3	-0.1	-0.4	-0.4	-0.4	-0.1	-1.0	-2.2	-2.1
Impedance of leg (left)	1.4	6.8	12.7	0.1	2.7	2.3	2.9	3.6	3.5	2.4	3.0	-3.0	0.1	2.3
Had menopause	1.4	1.7	4.5	1.7	2.1	-0.7	1.0	1.3	0.3	1.9	0.7	-1.3	-1.4	-0.6
Illnesses of mother	1.4	1.8	4.8	-0.6	-0.1	-2.1	0.8	-1.5	-1.6	-0.5	-0.3	-0.5	-2.0	-2.2
Hair/balding pattern: Pattern 4	1.4	3.4	7.4	-1.9	-1.8	-2.6	-1.1	-2.2	-1.6	-1.7	-1.2	-0.1	-2.0	-2.7
High blood pressure (siblings)	1.4	2.0	6.7	0.6	0.5	2.6	-0.2	1.5	1.6	0.1	0.6	0.4	2.0	2.3
Long-standing illness, disability or infirmity	1.4	2.1	4.9	-2.1	-1.3	1.1	-2.2	-0.3	-1.4	-0.9	-1.0	2.1	1.5	0.9
Mother’s age at death	1.4	1.8	3.6	-1.7	-1.4	-1.1	-0.8	-1.5	-1.6	-0.7	-1.9	1.6	0.0	-0.9
Bipolar Disorder (2018)	1.3	2.0	5.8	0.3	0.9	-1.7	0.0	1.3	-0.4	1.8	1.1	-1.8	-2.4	-1.7
Alzheimer’s Disease (in father)	1.3	1.4	2.7	-1.0	-1.1	-1.0	-1.1	-1.5	-1.5	-1.7	-1.2	1.3	-0.2	-1.0
High blood pressure	1.3	3.6	5.9	2.0	1.9	2.0	0.9	2.1	2.4	2.2	2.4	-0.5	1.4	2.0
Falls in the last year	1.3	1.8	5.7	-1.5	-0.5	-2.1	-1.1	-0.8	-0.7	-0.1	-0.4	0.1	-2.1	-2.4
Pulse wave Arterial Stiffness index	1.3	1.5	4.6	0.6	0.5	-1.8	1.0	-0.4	-0.8	-0.5	0.1	-1.3	-2.1	-2.0
Medication: Amlodipine	1.3	1.9	3.8	0.7	1.7	1.4	1.0	1.8	2.0	1.5	1.0	-1.1	0.3	1.6
Medication: Ventolin 100micrograms inhaler	1.3	1.6	5.1	0.8	1.1	2.3	0.7	1.1	0.8	0.2	1.3	-0.0	1.8	1.9
Comparative body size at age 10	1.3	3.7	11.3	-3.4	-2.7	-1.6	-2.2	-1.7	-1.6	-0.4	-1.7	1.9	-0.0	-1.6
Mineral and other dietary supplements	1.3	1.8	5.4	0.5	1.2	-1.6	1.3	0.3	0.5	0.7	1.1	-2.3	-2.0	-1.5
Medication: Gliclazide	1.3	1.5	7.6	-2.7	-0.6	-0.4	-0.5	-0.3	-1.7	-1.6	-0.7	1.4	0.3	-0.3
Supplements: Fish oil (including cod liver oil)	1.3	1.7	5.0	-0.0	0.1	2.1	-0.6	1.0	-0.2	0.5	0.1	1.8	2.2	2.1
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	3.7	1.7	1.9	-0.2	1.7	0.9	0.9	0.8	1.3	-0.5	-0.2	-0.2
Breastfed as a baby	1.2	1.5	3.6	0.9	-0.8	-0.7	-1.7	-1.4	-1.9	-1.5	-1.7	0.8	-0.2	-0.7
Pulse wave peak to peak time	1.2	1.4	4.1	-0.4	-0.4	1.8	-1.0	0.6	1.1	0.6	0.1	1.1	2.0	1.9
Shortness of breath walking on level ground	1.2	1.4	4.5	-0.8	-1.5	-0.8	-1.2	-1.4	-2.1	-1.6	-1.0	0.4	-0.3	-0.6
Medication: Seretide 50 evohaler	1.2	1.4	4.9	1.0	1.2	-0.2	0.8	1.4	0.5	0.9	1.3	-2.2	-1.4	-0.1
Supplements: Vitamin C	1.2	1.4	4.3	-2.1	-1.8	-0.6	-1.3	-0.8	-1.4	-0.9	-1.5	0.6	-0.2	-0.4
Medication: Aspirin	1.2	1.5	5.3	-0.7	0.2	1.8	-0.5	0.4	-0.8	-1.0	-0.3	1.7	2.3	1.7
Medication: Paracetamol	1.2	1.8	3.7	-0.2	-1.0	-1.9	-0.9	-1.5	-1.5	-0.9	-1.8	0.4	-1.4	-1.9
Impedance of whole body	1.2	5.9	10.1	0.1	2.4	2.8	2.6	3.1	3.2	2.1	2.5	-1.9	1.3	2.9
Age at First Birth	1.1	1.6	3.2	-1.7	-1.0	1.6	0.1	-0.4	-0.4	-1.3	-0.8	1.8	1.8	1.4
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	6.1	-2.5	-1.1	1.2	-0.9	0.1	-0.7	-0.7	-1.0	1.4	1.2	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	5.0	-2.2	-1.3	-1.9	-1.2	-1.5	-1.8	-1.1	-1.6	1.2	-0.9	-1.8
Happiness	1.1	1.3	2.3	-1.3	-1.5	-1.3	-1.1	-1.2	-1.4	-0.8	-1.2	0.2	-1.0	-1.2
Hypertension (Self-reported)	1.1	3.1	5.2	1.7	1.7	1.9	1.0	2.0	2.2	2.1	2.3	-0.3	1.4	1.8
Mood swings	1.1	1.9	3.9	-2.0	-1.7	-0.8	-1.3	-1.6	-1.6	-1.5	-1.7	0.9	-0.6	-0.9
Tinnitus: Yes, now most or all of the time	1.1	1.3	2.8	0.8	-1.5	-0.6	-1.7	-1.5	-1.4	-1.6	-1.1	0.5	-0.1	-0.5
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.5	-1.6	-0.4	1.3	-0.2	0.2	-1.3	-0.3	-0.1	1.9	1.9	1.3
Cardiovascular Disease	1.0	3.4	7.1	2.2	2.2	1.3	1.4	1.9	2.7	2.4	2.0	-1.0	0.7	1.3
Sensitivity / hurt feelings	1.0	1.7	3.7	0.0	-1.2	0.9	-1.0	-1.2	-1.3	-1.3	-1.6	1.9	1.8	0.9
Diabetes (father)	1.0	1.3	3.2	-1.7	-0.8	0.5	-0.7	-0.9	-1.8	-1.1	-1.0	1.6	0.9	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	5.7	-0.1	0.0	-1.9	0.3	-0.4	-0.1	0.4	-0.3	-1.4	-2.4	-1.7
Age when periods started (menarche)	1.0	2.4	6.6	0.3	1.2	2.5	1.7	1.4	1.4	1.0	1.2	-0.2	1.8	2.6
Fluid intelligence score	1.0	2.0	4.5	-1.3	0.3	-1.4	1.6	0.6	1.5	1.2	1.5	-2.1	-2.0	-1.1
Medication: Cholesterol lowering	1.0	1.6	4.9	0.2	0.4	2.2	-0.5	1.3	0.4	0.6	0.9	1.1	1.9	2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.2	8.2	1.7	2.3	-0.5	1.8	1.3	1.9	0.9	2.3	-2.9	-2.0	-0.2
Blood clot in the leg (DVT)	1.0	1.3	3.3	-1.5	-0.4	1.4	-0.3	0.2	-1.1	-0.4	-0.2	1.7	1.8	1.4
Qualifications: College or University degree	1.0	3.2	6.5	-2.3	-2.2	-1.0	-1.9	-2.2	-2.6	-2.1	-1.1	1.0	-0.4	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	3.7	-1.1	-1.9	-0.4	-1.1	-1.3	-0.9	-0.8	-0.8	1.4	0.4	-0.5
Risk taking	1.0	1.4	8.8	-3.0	0.3	-1.1	0.8	-0.1	-1.1	0.4	0.5	0.2	-1.2	-1.3
Neuroticism (2016)	0.9	1.3	4.0	-0.9	1.2	1.2	2.0	0.9	0.8	0.9	1.4	0.3	0.9	1.3
Triglycerides	0.9	1.5	3.3	0.2	0.8	-1.8	0.8	0.6	-0.1	1.8	1.0	-1.4	-1.8	-1.6
Height	0.9	17.8	51.3	4.8	3.6	-0.0	2.8	3.1	6.4	2.8	5.4	-7.2	-3.6	-0.5
Lung FVC	0.9	4.6	13.4	1.9	2.4	-0.5	2.3	1.9	1.9	1.7	2.5	-3.7	-2.4	-0.2
Impedance of leg (right)	0.9	4.2	7.6	0.2	2.2	1.9	2.2	2.7	2.8	1.7	2.4	-2.4	0.2	1.8
Financial difficulties in last 2 years	0.9	1.2	2.6	0.4	-0.5	-1.3	-0.5	-1.6	-1.3	-1.4	-1.0	-0.1	-1.1	-1.4
Time employed in main current job	0.9	1.1	3.2	1.4	0.6	0.3	0.8	0.8	1.1	1.1	1.8	-1.4	-0.7	0.2
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	7.7	1.4	2.1	-0.5	1.9	1.2	1.9	1.1	2.1	-2.8	-1.8	-0.2
Qualifications: A levels/AS levels or equivalent	0.9	2.1	6.4	-0.5	-1.7	-1.4	-1.5	-2.0	-1.3	-2.5	-0.7	0.4	-0.7	-1.4
Medication: Blood pressure	0.9	1.7	4.6	-0.1	1.1	1.9	0.9	1.3	0.5	1.0	2.1	0.4	1.5	1.8
Age at last live birth	0.9	1.3	3.9	0.6	0.7	1.9	0.8	1.0	0.7	-0.4	1.0	-0.1	1.6	2.0
Qualifications: nursing, teaching	0.9	1.3	3.0	-1.1	-0.9	-1.7	0.2	-1.0	-1.1	-1.3	-0.4	-0.7	-1.7	-1.5
Medication for cholesterol	0.9	1.3	3.1	-1.1	-1.5	-1.1	-0.7	-1.8	-1.7	-0.9	-0.9	0.4	-0.7	-1.1
Breast cancer (self-reported)	0.9	1.0	2.5	0.2	1.1	0.8	1.6	1.5	0.8	1.4	0.9	-0.7	0.3	0.9
Fractured/broken bones in last 5 years	0.9	1.2	3.8	2.0	1.6	-0.3	0.6	0.9	0.4	0.9	0.7	-1.4	-1.4	-0.6
Systolic blood pressure, automated reading	0.8	2.3	5.6	1.7	0.1	2.3	-1.1	0.9	1.3	-0.5	-0.2	1.2	2.4	2.3
Medication: Simvastatin	0.8	1.1	3.4	0.3	0.5	1.9	-0.6	1.0	0.1	0.3	0.7	1.0	1.6	1.7
Worrier / anxious feelings	0.8	1.6	3.4	-0.7	0.7	-0.3	1.8	0.7	1.1	1.8	1.8	-1.6	-1.3	-0.4
Standing height	0.8	7.8	22.3	2.6	2.9	0.3	2.6	2.4	3.8	1.5	3.9	-4.7	-2.2	-0.1
Birth weight	0.8	1.7	4.0	1.9	2.0	-0.7	0.6	0.7	1.1	0.2	1.9	-1.5	-1.4	-0.7
Leg pain on walking	0.8	1.0	2.3	0.9	-0.4	0.2	-1.5	-0.8	-0.8	-1.5	-0.9	1.5	0.9	0.1
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.8	1.1	-0.2	1.0	-0.2	0.6	1.7	0.8	1.2	-0.9	0.4	1.3
Miserableness	0.8	1.4	3.0	-1.7	-1.3	-1.6	-0.8	-1.1	-0.9	-0.8	-0.4	-0.4	-1.4	-1.5
Financial situation satisfaction	0.8	1.0	4.0	2.0	1.0	1.2	0.4	0.9	-0.2	-0.3	1.0	-0.7	0.8	1.3
Number of operations (self-reported)	0.8	1.2	4.4	-2.1	-0.1	-0.9	-0.5	-0.6	-1.0	-0.8	-1.5	1.3	0.0	-1.1
Body Mass Index (BMI) (2010)	0.7	0.9	2.6	-1.3	-0.9	-1.6	0.0	-0.8	-0.4	0.9	-0.2	-0.0	-1.1	-1.4
Lung FEV1/FVC ratio	0.7	3.4	12.0	-0.6	-2.3	0.3	-1.9	-1.7	-1.3	-1.1	-2.4	3.5	2.1	0.4
Trunk fat percentage	0.7	2.7	9.5	1.1	2.1	-0.0	1.5	1.7	2.0	3.1	1.3	-1.6	-0.9	-0.2
Qualifications: CSEs or equivalent	0.7	0.9	1.9	-0.7	0.9	0.9	1.4	1.2	0.6	0.6	1.3	-1.2	-0.2	0.8
Had other major operations	0.7	0.8	2.2	0.5	-0.6	0.6	-1.0	-0.4	-0.6	-0.7	-1.5	1.4	1.3	0.4
Qualifications: None of the above	0.7	1.4	5.2	2.1	0.7	0.8	-0.1	1.2	1.1	2.3	1.2	-0.4	0.4	0.8
Medication: Paracetamol	0.7	1.1	3.2	-0.5	-0.4	-1.8	-0.2	-1.0	-0.9	-0.3	-1.4	0.1	-1.4	-1.7
Medication for pain relief, constipation, heartburn	0.7	1.2	3.0	1.3	0.7	-0.4	0.9	0.7	0.8	1.3	1.3	-1.7	-1.4	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	1.8	0.6	0.9	1.4	0.7	1.0	1.3	0.3	0.6	0.0	1.0	1.3
Illnesses of father: High blood pressure	0.7	0.9	2.5	-0.6	0.4	1.6	1.1	0.8	1.0	-0.1	0.3	0.1	1.1	1.5
Worry (Nagel 2018)	0.6	1.3	2.8	-0.7	-0.0	-0.7	1.2	0.6	1.6	1.4	1.0	-1.7	-1.6	-0.6
Major Depression (MDD)	0.6	0.8	1.8	-1.4	1.3	0.2	1.3	1.2	-0.8	0.5	0.7	-0.6	-0.2	0.3
Lupus	0.6	0.9	2.7	-1.5	-0.4	0.5	-0.1	-0.0	-1.5	0.0	-1.0	1.7	0.9	0.7
Average weekly spirits intake	0.6	0.7	2.0	-0.0	0.2	1.1	-1.0	0.2	-0.9	-0.2	-0.0	0.8	1.4	1.4
Relative age of first facial hair	0.6	1.3	4.6	0.5	0.6	2.1	-0.2	1.0	0.7	0.7	0.7	0.1	1.6	2.1
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.7	1.2	1.6	1.1	0.1	0.8	0.0	-0.4	0.0	0.3	1.0	0.9
Taking other prescription medications	0.6	0.9	4.0	-1.0	-0.5	-0.6	-1.2	-0.5	-2.0	-0.9	-0.9	0.6	-0.2	-0.8
Serious illness, injury or assault to yourself	0.6	0.7	2.1	0.7	1.1	-0.6	0.7	0.8	-0.0	0.2	0.8	-1.2	-1.4	-0.9
Hayfever, allergic rhinitis or eczema	0.6	1.2	2.6	-0.3	1.4	-1.5	1.4	0.2	-0.6	1.3	-0.2	-0.7	-1.6	-1.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.7	1.6	0.2	-0.7	-1.2	-0.9	0.1	-1.3	-0.5	0.1	-0.5	-0.8
Trunk fat mass	0.6	2.8	7.1	1.3	2.1	-0.6	1.4	1.4	1.9	2.7	1.5	-1.9	-1.6	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.3	-1.2	-0.8	-1.4	0.3	-0.7	-0.8	0.0	0.2	-0.7	-1.5	-1.4
Number of live births	0.6	0.9	3.4	-0.5	1.8	-0.4	0.7	1.6	0.4	1.4	-0.1	-0.8	-0.4	-0.1
Impedance of arm (left)	0.6	2.8	6.6	-0.8	1.1	2.5	1.7	1.9	1.8	1.0	1.3	-0.5	2.0	2.6
Exposure to tobacco smoke at home	0.6	0.7	1.7	1.3	-0.1	-0.4	-1.0	-0.9	-0.8	-0.7	-1.2	1.0	0.2	-0.3
Gout (self-reported)	0.6	0.9	3.6	1.9	1.3	0.7	0.5	0.8	0.9	0.9	0.8	0.0	0.5	0.5
Eye problems/disorders: None of the above	0.6	0.7	2.6	0.5	1.2	-0.4	1.1	0.7	1.1	1.6	0.6	-0.5	-0.4	-0.4
Migraine (self-reported)	0.6	0.7	2.5	-0.1	-0.5	-1.6	-0.7	-0.6	0.3	-0.1	-0.6	0.0	-1.1	-1.6
Heart disease (mother)	0.6	0.8	1.7	-1.0	-1.3	1.2	-0.5	0.4	0.8	0.3	0.7	0.3	1.1	1.3
Whole body fat mass	0.6	2.5	6.3	1.5	1.9	-1.1	1.1	1.1	1.5	2.5	1.2	-1.8	-1.9	-1.3
Leg fat mass (right)	0.6	2.2	6.1	1.0	1.3	-1.8	0.6	0.4	0.7	1.9	0.6	-1.7	-2.5	-2.1
Arm predicted mass (right)	0.6	3.2	9.4	1.7	1.2	-2.1	1.0	-0.0	1.1	1.1	1.3	-2.5	-3.1	-2.3
Number of full sisters	0.6	0.8	2.3	0.1	0.4	-1.4	-0.2	-0.5	-0.9	-0.0	-0.8	-0.7	-1.4	-1.5
Ever had bowel cancer screening	0.6	0.7	2.9	-0.7	1.0	-0.5	0.5	0.9	0.3	1.7	0.2	-0.5	-1.0	-0.6
Osteoarthritis (self-reported)	0.6	0.8	2.0	-1.4	-0.8	-1.0	-0.8	-0.8	-0.4	-0.8	-0.7	1.0	-0.4	-1.3
Ever taken oral contraceptive pill	0.6	0.7	2.8	-1.7	0.2	1.0	0.5	0.3	-0.2	-0.4	-0.1	1.3	1.1	0.7
Hearing aid user	0.6	0.7	2.5	-0.1	0.7	-0.8	0.8	0.6	0.2	1.3	0.5	-0.8	-1.6	-0.8
High cholesterol (Self-reported)	0.6	1.1	3.3	1.8	0.7	0.7	-0.9	1.3	1.2	1.2	1.3	-0.9	-0.1	0.3
Medication: Lisinopril	0.6	0.8	2.4	0.0	0.6	1.4	-0.3	0.1	-0.9	-0.2	0.0	1.2	1.6	1.4
Age started oral contraceptive pill	0.6	0.7	1.7	1.3	0.9	-0.7	1.1	0.1	0.4	0.9	0.4	-0.8	-1.3	-0.9
Basal cell carcinoma (self-reported)	0.6	0.8	3.9	2.0	0.7	0.2	-0.1	0.3	1.5	0.6	0.8	-0.6	-0.4	-0.0
Alcohol drinker status: Previous	0.6	0.7	1.4	0.9	0.6	-0.4	0.8	0.5	0.7	1.0	0.5	-1.2	-1.2	-0.6
Leg fat mass (left)	0.6	2.2	5.6	1.0	1.4	-1.7	0.7	0.6	0.8	2.0	0.7	-1.7	-2.4	-1.9
Arm predicted mass (left)	0.6	2.9	9.2	2.0	0.8	-2.1	0.3	-0.3	0.8	0.6	1.1	-2.3	-3.0	-2.4
Depression (Nagel 2018)	0.5	0.8	2.9	-0.1	0.0	-1.2	0.8	0.1	0.4	0.9	0.0	-1.2	-1.7	-1.1
Intelligence (Savage-Jansen 2018)	0.5	1.7	4.1	0.1	-1.4	-1.5	-0.6	-2.0	-1.7	-1.5	-1.1	-0.4	-1.2	-1.3
Chronotype (morning person)	0.5	1.1	3.4	-1.4	-0.7	-1.7	-0.4	-0.3	0.1	-0.4	-0.2	-0.5	-1.6	-1.8
Ever had hysterectomy (womb removed)	0.5	0.6	1.5	-1.1	0.9	0.7	0.3	1.1	0.6	1.2	0.3	0.1	0.6	0.7
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	2.6	-0.1	-0.5	0.5	-0.8	-0.1	-1.3	-1.6	-0.1	0.4	0.4	0.4
Fed-up feelings	0.5	1.0	3.6	-0.1	-0.2	-1.6	-0.5	-0.6	-0.8	0.3	-0.8	-0.7	-1.9	-1.4
Alcohol usually taken with meals	0.5	0.7	1.8	-0.2	-1.2	-0.4	-0.9	-0.9	-1.3	-0.8	-1.2	0.8	0.1	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	5.1	-2.3	-0.9	-1.1	-0.7	-0.8	-1.1	-0.6	-0.9	1.1	-0.3	-0.9
Mouth/teeth dental problems	0.5	0.8	4.2	-0.0	2.0	0.8	1.3	0.6	-0.1	0.4	0.1	0.5	0.7	0.8
Allergy	0.5	1.1	3.0	0.1	-1.3	1.5	-0.8	0.2	1.3	-0.3	0.4	0.4	1.4	1.7
Mouth/teeth dental problems: Dentures	0.5	0.8	3.9	2.0	-0.9	-0.8	-1.4	-0.3	0.6	0.1	-0.3	-0.3	-0.5	-0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.8	-1.2	-1.3	0.7	-1.2	0.1	0.5	-0.1	-0.6	0.7	0.6	0.7
Body fat percentage	0.5	2.0	7.8	0.9	1.8	-0.5	1.2	1.3	1.5	2.8	0.9	-1.3	-1.2	-0.7
Arm fat-free mass (right)	0.5	2.5	7.8	1.7	0.9	-1.9	0.5	-0.2	0.9	0.4	0.9	-2.2	-2.8	-2.2
Number of full brothers	0.5	0.6	2.3	-0.4	0.5	1.2	-0.3	0.7	-0.1	-0.2	-0.3	0.8	1.5	1.1
Worry too long after embarrassment	0.5	0.8	3.0	1.0	0.4	0.4	0.8	0.7	1.0	0.5	1.4	-1.7	-0.5	0.1
Wheeze or whistling in the chest in last year	0.5	0.9	2.2	0.6	1.4	-0.8	0.2	0.6	0.0	0.9	1.1	-1.1	-1.5	-0.9
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.3	-1.1	-0.6	-1.1	-0.4	-0.3	-0.7	0.1	-0.3	-0.5	-1.1	-1.0
Overall health rating	0.5	1.1	2.8	-0.8	1.7	0.2	1.5	1.4	0.5	1.4	1.1	-0.8	-0.6	-0.0
Had major operations	0.5	0.5	1.5	-1.2	-0.0	-0.8	-0.3	-0.3	-0.7	-1.1	-0.3	-0.1	-0.9	-1.0
Illnesses of father: Heart disease	0.5	0.7	1.3	1.1	-1.0	-0.9	-0.9	-1.1	-0.6	0.2	-0.7	-0.1	-0.6	-1.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.1	-0.1	0.1	-1.3	-0.1	-0.1	-0.1	0.3	0.1	-1.1	-1.4	-1.3
Eye problems/disorders: Cataract	0.5	0.6	1.9	-0.3	0.2	1.3	0.6	0.6	0.4	0.2	1.1	-0.5	0.8	1.4
Guilty feelings	0.5	0.8	2.9	-0.6	0.2	-1.3	-0.1	-0.1	0.3	0.1	0.4	-1.2	-1.7	-1.5
Commuting to job workplace: Public transport	0.5	0.6	1.5	0.7	-0.5	-0.2	-1.2	-0.9	-0.7	-1.1	-0.8	0.7	0.2	-0.2
Arm fat-free mass (left)	0.5	2.7	8.1	2.0	1.0	-1.9	0.4	-0.2	0.8	0.8	1.0	-2.1	-2.8	-2.3
Ovarian Cancer	0.4	0.5	1.8	1.4	0.7	0.7	0.1	0.6	0.6	0.1	1.2	-0.5	0.0	0.6
Prostate Cancer	0.4	0.6	2.0	0.9	0.6	0.3	1.4	0.7	-0.1	1.0	-0.2	-1.1	-0.4	0.3
BMI	0.4	2.3	7.2	-0.3	-0.7	-2.7	-1.4	-1.6	-1.1	0.4	-1.4	1.1	-1.4	-2.5
Tanning	0.4	5.0	17.4	-0.0	-1.3	-3.9	-1.0	-2.0	-1.4	-0.1	-1.4	-0.6	-3.4	-4.2
Angina	0.4	0.5	1.3	-1.2	-0.7	-0.6	-0.9	-0.4	-0.6	-1.0	0.4	-0.0	-0.7	-0.9
Medication for hormone replacement therapy	0.4	0.4	1.5	1.2	0.8	0.5	0.3	0.3	0.9	-0.8	-0.2	-0.4	0.5	0.6
Vitamin and mineral supplements	0.4	0.5	1.8	0.8	0.6	0.1	0.6	0.7	0.6	1.2	1.3	-0.8	-0.2	0.3
Medication: Co-codamol	0.4	0.5	1.6	0.7	0.7	-1.3	0.3	-0.5	-0.7	0.3	0.3	0.2	-0.8	-1.3
Sitting height	0.4	2.5	7.3	1.0	0.9	-1.5	0.7	0.0	1.9	-0.8	1.5	-2.7	-2.5	-1.8
Chronic bronchitis/emphysema (father)	0.4	0.4	1.3	0.9	0.5	-0.4	0.4	0.3	0.0	0.5	0.6	-1.1	-1.1	-0.4
Number of incorrect matches in round	0.4	0.7	2.8	-1.7	-0.7	-1.2	-0.5	-0.4	-0.5	0.4	0.3	0.4	-0.9	-1.1
Hearing difficulty/problems with background noise	0.4	0.7	2.0	0.7	-0.1	-1.3	-0.7	-0.2	0.1	1.1	0.0	-0.3	-1.2	-1.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.5	0.4	0.5	-1.2	0.1	-0.1	-0.6	0.1	0.3	-0.8	-1.2	-0.7
Pain all over the body in last month	0.4	0.4	1.7	-0.9	0.0	-0.6	0.5	0.2	0.8	1.3	0.7	-0.0	-0.5	-0.4
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.7	1.0	-0.1	-0.3	-0.7	-0.4	-1.2	-0.7	-1.3	0.7	0.2	-0.3
Weight	0.4	2.0	4.8	1.6	1.2	-1.6	0.5	0.1	1.1	1.4	0.9	-1.6	-2.2	-1.9
Trunk fat-free mass	0.4	2.3	7.7	1.7	0.4	-2.1	0.2	-0.7	0.1	-0.0	0.9	-1.9	-2.8	-2.4
Noisy workplace	0.4	0.5	0.9	0.9	1.0	0.7	0.8	0.6	-0.9	0.0	0.8	0.1	0.4	0.7
Prospective memory result	0.4	0.5	2.4	1.5	0.6	0.2	0.3	0.6	0.9	-0.2	0.2	-0.9	-0.2	0.2
Trunk predicted mass	0.4	2.3	7.7	1.6	0.4	-2.1	0.1	-0.8	0.0	-0.1	0.9	-1.9	-2.8	-2.4
Length of working week for main job	0.4	0.5	1.6	-0.2	0.9	0.6	0.7	0.6	1.3	0.3	0.8	-0.7	-0.2	0.5
Leg fat percentage (right)	0.4	1.3	3.7	0.6	1.2	-1.3	0.6	0.5	0.4	1.9	0.3	-1.0	-1.8	-1.5
Health satisfaction	0.4	0.5	1.1	-0.4	-0.6	0.8	-0.8	-0.1	-0.8	-0.7	-0.6	0.9	1.1	0.9
Emphysema/chronic bronchitis	0.4	0.4	2.7	1.6	0.8	0.5	0.6	0.2	-0.4	-0.1	0.2	-0.1	0.4	0.4
Angina (self-reported)	0.4	0.5	1.1	-1.0	-0.7	-0.6	-0.9	-0.4	-0.6	-1.0	0.4	-0.0	-0.7	-0.8
Comparative height size at age 10	0.4	2.3	5.8	1.7	1.1	0.5	1.2	1.3	2.3	1.4	2.1	-2.4	-0.8	0.3
Illnesses of siblings: Diabetes	0.4	0.5	4.1	-2.0	-0.1	0.3	-0.1	0.4	-0.6	-0.2	-0.6	0.4	0.6	0.2
Whole body fat-free mass	0.4	2.3	7.5	1.6	0.5	-2.1	0.3	-0.7	0.3	0.1	0.8	-1.9	-2.7	-2.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.9	-1.2	-1.4	-0.8	-0.3	-0.7	-0.4	-0.5	-0.2	0.0	-0.6	-0.9
Osteoporosis (self-reported)	0.4	0.5	1.5	0.6	1.1	0.7	1.2	0.5	0.1	-0.3	0.5	-0.6	0.2	0.7
Whole body water mass	0.4	2.2	7.2	1.6	0.5	-2.1	0.3	-0.7	0.2	0.1	0.8	-1.8	-2.7	-2.4
Average weekly champagne plus white wine intake	0.4	0.5	1.5	0.1	-0.9	-0.4	-0.7	-1.1	-0.3	-0.7	-0.3	1.2	0.4	-0.6
Medication: Blood pressure	0.4	0.7	2.5	0.1	-0.0	0.8	-0.6	0.6	0.9	0.7	-0.3	1.1	1.6	0.9
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.2	1.0	0.1	0.3	-0.4	0.5	1.5	1.2	0.3	0.0	0.2	0.4
Basal metabolic rate	0.4	2.3	7.0	1.8	0.9	-2.0	0.5	-0.3	0.6	0.6	1.0	-2.0	-2.6	-2.2
Leg fat percentage (left)	0.4	1.5	5.0	0.4	1.4	-1.2	0.9	0.8	0.5	2.2	0.5	-1.2	-1.7	-1.3
Average weekly beer plus cider intake	0.4	0.6	1.6	0.8	0.5	-0.6	0.5	0.3	0.5	0.5	1.2	-1.1	-1.3	-0.4
Irritability	0.4	0.6	1.6	-1.2	-0.2	-0.9	-0.3	-0.6	-0.9	-0.2	-1.0	-0.2	-1.1	-1.0
Unable to work because of sickness or disability	0.4	0.5	1.5	0.4	0.6	-0.3	0.6	0.3	1.2	1.1	0.4	-0.7	-0.9	-0.5
Schizophrenia vs Biploar Disorder	0.3	0.4	1.2	0.2	1.1	-0.6	0.8	0.1	0.6	1.0	0.0	-0.4	-0.4	-0.4
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.2	-0.1	-0.6	-1.4	0.4	-0.8	-0.2	-0.1	-0.3	-1.2	-1.5	-1.0
HbA1C	0.3	0.4	1.1	-0.9	0.0	0.1	0.4	0.5	-0.0	1.0	-0.1	0.7	0.7	0.7
Primary Biliary Cirrhosis	0.3	0.4	1.0	-0.8	-1.0	-0.0	0.1	-0.8	-0.9	-0.8	0.1	0.4	0.3	-0.1
Rheumatoid Arthritis	0.3	0.5	2.3	-1.0	0.6	0.0	0.1	0.7	-0.1	0.5	1.5	-0.3	-0.8	-0.1
Blood Eosinophil Count	0.3	2.3	6.2	0.9	2.2	0.8	1.6	1.9	1.2	2.5	1.7	-1.1	0.1	0.8
Allergy or Eczema	0.3	0.9	2.0	-0.3	1.1	-1.2	1.4	0.1	-0.5	1.4	0.1	-0.2	-1.3	-1.3
Neuroticism	0.3	0.8	2.8	-1.3	-0.7	-1.1	0.3	-0.3	0.0	0.7	0.1	-0.9	-1.7	-1.2
Leg fat-free mass (left)	0.3	1.8	5.3	1.6	0.6	-2.0	0.3	-0.8	0.2	0.2	0.4	-1.4	-2.3	-2.3
Current tobacco smoking	0.3	0.4	1.3	0.4	0.0	-1.1	-0.7	-0.8	0.0	-0.5	0.1	-0.2	-1.0	-1.0
Medication: Atenolol	0.3	0.3	1.0	-0.3	0.3	0.7	0.6	0.1	0.1	0.4	0.1	0.8	1.0	0.9
Leg predicted mass (left)	0.3	1.7	5.1	1.5	0.5	-2.0	0.3	-0.8	0.1	0.2	0.4	-1.3	-2.2	-2.3
Medication: Ramipril	0.3	0.4	1.5	-1.2	-0.5	0.8	0.3	0.7	0.4	0.7	0.2	0.2	0.9	0.7
Impedance of arm (right)	0.3	1.3	3.1	-0.5	0.9	1.7	1.0	1.4	1.1	0.8	0.8	-0.4	1.4	1.8
Asthma	0.3	0.6	1.9	0.7	1.0	-0.4	0.1	0.5	-0.9	0.3	0.8	-1.4	-1.0	-0.6
Arm fat mass (right)	0.3	1.2	2.5	1.4	1.2	-1.2	0.3	0.3	0.7	1.6	0.5	-0.9	-1.4	-1.4
Birth weight of first child	0.3	0.6	2.1	0.6	0.8	0.2	1.1	0.3	0.5	0.1	1.2	-1.5	-0.8	-0.1
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.1	1.0	0.4	-0.4	0.0	0.6	0.3	0.8	0.6	-0.9	-0.8	-0.2
Number of children fathered	0.3	0.4	1.1	0.3	-0.2	0.2	-0.5	-0.4	-1.0	-1.0	-0.5	1.1	0.5	0.3
Neck or shoulder pain in last month	0.3	0.5	1.4	-0.7	-0.2	-0.5	-0.2	-0.7	-0.6	0.9	-1.0	1.2	-0.2	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.1	-0.7	-0.3	1.1	0.3	0.7	0.2	-0.1	0.3	-0.6	0.4	1.0
Commuting to job workplace: Walk	0.3	0.3	2.0	-0.3	-0.1	-0.0	-0.0	-0.3	-1.4	0.5	-0.8	0.6	0.1	0.1
Asthma (self-reported)	0.3	0.6	1.9	0.7	1.2	-0.3	0.3	0.8	-0.7	0.6	0.9	-1.4	-0.8	-0.5
Illnesses of father: None of the above (group 1)	0.3	0.4	0.9	-0.1	0.8	-0.5	0.3	1.0	0.8	1.0	0.4	-0.4	-0.6	-0.5
Arm fat mass (left)	0.3	1.1	3.4	1.2	1.3	-0.9	0.7	0.5	0.9	1.9	0.6	-0.9	-1.2	-1.0
Wears glasses or contact lenses	0.3	0.3	0.7	0.5	0.2	-0.8	0.1	0.1	0.6	0.2	0.4	-0.7	-0.8	-0.7
Medication: Bendroflumethiazide	0.3	0.4	1.4	0.1	0.2	1.0	0.0	0.4	0.6	0.3	-0.2	0.6	1.1	1.2
Alcohol drinker status: Never	0.3	0.4	1.9	-1.2	0.2	-0.4	0.8	-0.2	-1.4	0.0	-0.5	0.4	-0.1	-0.2
Depressed Affect (Nagel 2018)	0.2	0.4	1.7	-1.3	-0.5	-0.8	-0.3	-0.4	-0.4	0.2	-0.8	0.3	-0.8	-0.6
Neuroticism (Nagel 2018)	0.2	0.5	1.5	-1.2	0.1	-0.8	0.6	0.1	0.7	0.5	0.1	-0.7	-1.1	-0.4
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.7	0.4	0.4	0.3	0.1	0.3	0.3	1.3	-0.4	0.6	0.5	0.0
Waist Hip Ratio (WHR)	0.2	0.9	3.2	-0.3	-0.2	1.4	0.2	-0.5	-0.3	-1.0	0.1	1.4	1.8	1.0
Smoking Status	0.2	0.4	1.1	-0.0	0.4	0.7	-0.3	-0.4	0.4	-1.0	-0.3	0.9	1.0	0.9
Respiratory disease	0.2	0.5	1.8	-0.2	1.3	0.0	0.7	1.0	-0.5	0.7	0.6	-0.8	-0.3	0.0
Number of treatments/medications taken	0.2	0.3	1.2	0.2	-0.0	0.0	-0.9	-0.0	-0.9	-0.2	-1.1	0.6	0.2	0.1
Hearing difficulty/problems: Yes	0.2	0.3	1.1	-0.5	-0.5	-0.6	-0.6	-0.0	0.2	1.0	-0.5	0.1	-0.6	-0.5
Maternal smoking around birth	0.2	0.3	1.2	-0.4	-0.3	0.6	-1.1	0.2	0.7	-0.5	0.5	0.5	0.6	0.6
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.0	0.4	0.6	0.2	0.0	0.2	-0.3	0.5	-0.7	1.0	0.7	0.1
Multivitamins +/- minerals	0.2	0.3	0.9	-0.0	-0.5	0.1	-0.8	-0.4	0.1	-1.0	-0.8	0.5	0.3	0.1
Body mass index (BMI)	0.2	1.0	3.1	0.6	0.1	-1.7	-0.7	-0.8	-0.5	0.8	-0.7	0.4	-1.2	-1.8
Waist circumference	0.2	0.6	2.1	0.6	-0.2	-1.2	-0.7	-0.8	-0.4	0.6	-0.7	0.3	-0.9	-1.4
Neuroticism score	0.2	0.4	1.7	-0.6	-0.5	-0.7	0.2	-0.3	0.2	0.4	0.2	-1.0	-1.3	-0.7
Arm fat percentage (right)	0.2	0.6	3.0	0.5	0.6	-0.9	0.1	0.1	0.1	1.7	-0.1	-0.1	-0.8	-1.1
Hip circumference	0.2	1.1	3.2	0.9	-0.2	-1.6	-0.7	-0.9	0.0	0.6	-0.4	-0.6	-1.7	-1.8
Medication: Lansoprazole	0.2	0.2	0.9	-0.9	-0.6	-0.2	-0.4	0.0	-0.2	0.3	-0.1	-0.0	-0.5	-0.3
Peak expiratory flow (PEF)	0.2	0.4	1.2	0.1	0.3	-0.7	0.4	0.2	0.9	-0.4	0.9	-1.1	-0.9	-0.5
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.2	-1.1	-0.2	0.2	-0.8	0.0	-0.5	0.1	0.2	0.7	0.2	0.2
Loud music exposure frequency	0.2	0.2	1.5	0.3	0.1	-0.5	-0.3	-0.1	0.2	-1.2	-0.3	-0.3	-0.5	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.2	0.9	0.5	-0.2	0.4	-0.3	0.9	-1.1	0.1	-0.3	-0.1	-0.1
Headache pain in last month	0.2	0.3	0.8	-0.9	-0.3	-0.4	-0.4	-0.1	-0.4	0.0	-0.8	-0.1	-0.6	-0.6
Glaucoma (self-reported)	0.2	0.2	0.6	0.5	-0.1	-0.4	-0.0	0.1	-0.1	0.3	-0.6	-0.6	-0.7	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.0	-0.3	-0.5	-0.6	-1.0	-0.2	-0.3	0.1	-0.4	0.7	-0.1	-0.8
Chest pain or discomfort	0.2	0.2	0.6	0.3	-0.2	-0.6	-0.6	0.0	-0.5	0.3	0.7	-0.4	-0.8	-0.6
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.7	-0.5	-0.6	0.3	-0.5	0.0	0.9	0.2	-0.3	0.3	0.4	0.3
Knee pain experienced in last month	0.2	0.3	1.7	-0.1	-0.2	-0.2	-0.8	-0.2	-0.4	-0.0	-0.4	1.3	0.1	-0.2
Leg fat-free mass (right)	0.2	1.3	3.5	1.5	0.7	-1.5	0.5	-0.5	0.4	0.4	0.6	-1.3	-1.9	-1.8
Arm fat percentage (left)	0.2	0.6	3.5	0.4	0.9	-0.7	0.5	0.4	0.4	1.9	0.1	-0.2	-0.7	-0.8
Smoking status: Current	0.2	0.3	0.8	0.5	0.4	-0.9	-0.2	-0.4	0.3	-0.2	0.4	-0.4	-0.9	-0.7
Leg predicted mass (right)	0.2	1.2	3.3	1.5	0.7	-1.5	0.4	-0.5	0.3	0.3	0.5	-1.3	-1.8	-1.7
Ever depressed for a whole week	0.2	0.3	1.1	-0.2	0.2	-0.0	-0.3	-0.1	-0.7	-1.0	-0.3	0.8	0.6	0.3
Commuting to job workplace: Cycle	0.2	0.3	0.9	0.4	0.3	0.3	0.2	0.6	0.6	0.2	0.8	-0.9	-0.5	0.1
Myopia	0.2	0.3	1.0	-0.8	0.4	0.9	-0.1	0.6	0.6	-0.0	-0.2	0.0	0.6	1.0
Pain experienced in last month	0.2	0.4	1.9	0.4	-0.1	-0.1	-0.3	-0.8	-1.0	-1.4	-0.5	0.2	0.2	-0.0
Coronary Artery Disease (CAD)	0.1	0.1	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.1	-0.6
Blood White Count	0.1	0.5	2.6	0.1	0.2	0.1	-0.8	-0.2	-0.9	-0.3	-0.7	1.6	0.7	0.2
Nervous feelings	0.1	0.2	0.9	0.1	0.3	0.2	0.9	0.2	0.6	0.6	0.5	-0.5	-0.2	0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.5	0.4	0.5	0.1	0.2	0.3	-0.1	0.7	-0.2	0.1	-0.2	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	-0.2	-0.5	0.1	-0.3	0.1	0.2	-0.3	0.5	-0.4	-0.2	0.3
Medication: Allopurinol	0.1	0.2	0.7	0.8	0.5	0.0	-0.2	-0.2	-0.3	-0.3	-0.1	0.8	0.4	0.0
Alcohol intake frequency.	0.1	0.3	1.3	0.2	1.1	-0.1	1.1	0.3	-0.4	0.5	-0.7	0.4	0.0	0.0
Back pain experienced in last month	0.1	0.1	0.3	0.5	0.2	-0.2	-0.5	0.1	0.5	0.0	-0.0	0.1	-0.2	-0.4
Number of self-reported non-cancer illnesses	0.1	0.1	0.4	-0.2	0.2	0.3	-0.6	0.5	-0.1	0.4	-0.1	0.1	-0.1	0.2
Eye problems/disorders: Glaucoma	0.1	0.2	1.0	1.0	-0.0	0.4	-0.0	0.1	-0.3	-0.3	-0.5	-0.1	0.0	0.1
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.6	-0.3	-0.8	0.2	-0.3	-0.0	0.3	0.1	-0.3	-0.3	-0.2	0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

TRIP6

Models

Trait associations