Hub : Genes

EPHB4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.2520	0.0610	1.1e-07	0.162	NA	0.101	NA	0.155	3.5e-12	NA	5.1e-08	NA	1.1e-11
2	GTEx	Esophagus Mucosa	0.1580	0.0550	2.7e-05	0.032	NA	0.067	NA	0.041	3.1e-03	NA	2.9e-05	NA	9.5e-04
3	GTEx	Whole Blood	0.1320	0.0440	2.0e-05	0.098	NA	0.075	NA	0.091	2.5e-09	NA	1.9e-07	NA	1.0e-08
4	NTR	Blood	0.0202	0.0081	9.0e-05	0.009	0.014	0.008	0.013	0.009	5.8e-04	1.3e-05	7.1e-04	3.0e-05	4.4e-04
5	YFS	Blood	0.3747	0.0375	0.0e+00	0.322	0.409	0.423	0.417	0.425	7.0e-109	2.8e-146	7.9e-153	3.6e-150	4.9e-154
6	TCGA	Glioblastoma Multiforme	0.1640	0.0960	7.3e-03	0.111	0.032	0.070	NA	0.055	3.1e-04	3.8e-02	3.8e-03	NA	9.0e-03
7	TCGA	Pheochromocytoma and Paraganglioma	0.1960	0.0900	5.0e-04	0.069	0.103	0.057	NA	0.069	1.1e-03	6.9e-05	2.8e-03	NA	1.0e-03
8	TCGA	Testicular Germ Cell Tumors	0.2980	0.0990	1.1e-06	0.204	0.147	0.049	NA	0.176	9.2e-08	6.9e-06	7.9e-03	NA	8.1e-07
9	TCGA	Thyroid Carcinoma	0.0480	0.0300	3.4e-03	0.044	0.013	0.014	NA	0.022	3.6e-05	1.7e-02	1.3e-02	NA	2.8e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.0	1.6	3.2	-0.5	-0.6	-1.5	-0.6	-0.6	-1.8	-1.4	1.7	-1.5
Bipolar Disorder or Schizophrenia	2.0	4.8	9.5	-2.0	-1.5	-1.5	-0.9	-0.1	-3.0	-3.1	2.8	-2.7
Depressed Affect (Nagel 2018)	0.2	0.4	1.1	0.1	0.1	-1.1	-0.9	-0.6	0.2	-0.3	0.8	-0.6
Depression (Nagel 2018)	0.4	0.6	1.5	0.1	-0.2	-0.9	-0.8	-0.6	-1.2	-1.1	0.7	-0.5
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.4	0.2	-0.9	1.1	0.1	1.2	-1.0	0.2	-0.2	0.8
Neuroticism (Nagel 2018)	0.5	1.1	2.7	-0.1	0.5	-1.6	-0.5	-0.5	-0.9	-1.2	1.5	-1.2
Schizophrenia (2018)	1.7	3.5	8.1	-2.2	-1.4	-0.7	-0.6	0.4	-2.4	-2.9	2.2	-2.2
Schizophrenia vs Biploar Disorder	0.9	1.2	3.0	-1.0	-1.2	0.9	1.7	1.7	-1.2	-0.8	0.1	0.1
Worry (Nagel 2018)	1.2	2.5	5.2	-0.6	1.3	-1.8	0.1	-0.6	-2.0	-2.0	2.3	-2.1
Alzheimer’s Disease (in mother)	2.6	3.1	8.8	-2.5	-1.3	2.7	1.9	3.0	-0.0	-0.1	-0.2	0.5
Alzheimer’s Disease (in father)	0.5	0.5	2.2	-0.4	-0.2	0.7	0.5	0.7	1.5	0.7	-0.4	0.6
Alzheimer’s Disease (including proxy)	1.9	2.7	9.0	-3.0	-0.9	2.0	1.2	2.8	0.5	-0.6	0.6	-0.3
Crohns Disease (2017)	3.4	7.4	15.6	-1.7	0.2	-2.6	-1.1	-1.1	-3.1	-3.7	3.9	-3.9
Irritable Bowel Disease (IBD)	4.8	11.5	20.7	-1.1	2.4	-4.1	-2.3	-2.6	-3.6	-3.9	4.4	-4.5
Ulcerative Colitis (UC)	4.6	8.7	17.1	0.7	3.7	-4.1	-3.0	-3.5	-2.4	-1.9	2.6	-3.1
Major Depression (MDD)	0.7	0.9	2.8	0.9	0.9	-1.7	-1.1	-1.4	-0.2	0.1	0.4	-0.4
Reaction Time	1.7	3.2	5.5	-0.5	1.9	-2.1	-1.0	-1.5	-1.8	-2.4	2.0	-2.1
Verbal and Numeric Reasoning (VNR)	0.2	0.6	2.2	-0.7	-0.6	0.6	-0.1	0.8	-1.5	-0.8	0.7	-0.3
Breast Cancer	0.3	0.8	1.8	0.8	-1.1	0.5	0.0	0.7	0.8	1.3	-0.7	1.3
Ovarian Cancer	0.8	1.1	2.9	1.5	0.8	-1.3	-1.4	-1.7	-0.1	0.6	-0.1	-0.0
Prostate Cancer	1.0	1.3	2.6	0.1	0.7	-1.6	-0.4	-1.1	-1.0	-1.4	1.5	-1.6
Age at First Birth	1.9	2.8	6.1	1.9	1.2	-0.2	-2.5	-1.4	2.2	2.0	-1.4	1.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.9	1.3	3.5	-1.9	-1.3	0.3	0.8	1.4	-0.2	-1.2	1.2	-1.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	3.8	6.2	14.4	-2.9	-1.0	-1.0	0.7	0.9	-2.4	-3.8	3.7	-3.2
Mean Putamen Volume	2.3	2.6	6.2	-0.1	-1.0	2.5	1.6	2.3	1.1	1.2	-1.5	2.0
Fasting Glucose	3.6	4.3	10.2	1.7	0.2	1.2	0.3	-0.2	2.8	3.2	-3.0	2.7
HbA1C	1.1	1.2	2.4	-1.5	-1.3	-0.2	0.6	0.6	0.7	-1.2	1.4	-1.5
HDL Cholesterol	0.7	1.2	4.8	0.3	0.6	-1.3	0.1	-1.0	-2.2	-1.4	0.5	-0.9
LDL Cholesterol	1.0	1.6	5.9	-0.9	0.4	-0.5	-0.7	-0.1	-2.4	-1.7	1.2	-1.4
Lupus	0.2	0.4	1.6	0.0	-0.2	-0.9	0.5	-0.2	1.3	-0.2	0.5	-0.6
Neuroticism (2016)	0.8	1.1	3.0	1.2	0.8	-1.3	-1.7	-1.6	0.5	0.5	-0.2	0.1
Primary Biliary Cirrhosis	0.4	0.5	1.8	0.9	1.4	0.2	-0.2	-0.1	0.4	0.7	-0.8	0.9
Rheumatoid Arthritis	1.1	1.5	5.5	1.5	1.0	-2.3	-1.2	-1.6	-0.6	0.4	0.7	-0.5
Schizophrenia (2014)	1.8	3.9	8.7	-1.7	-0.6	-1.4	-0.6	-0.2	-2.9	-3.0	2.4	-2.6
Triglycerides	0.9	1.4	3.1	-1.7	0.1	0.2	0.2	0.6	-1.1	-1.8	1.7	-1.6
Type 2 Diabetes (T2D) (2012)	0.8	0.9	3.3	-1.8	-0.9	0.5	0.2	1.2	0.4	-0.9	0.8	-1.0
Ulcerative Colitis	4.1	5.9	11.2	-0.4	3.3	-3.0	-1.6	-2.1	-2.2	-2.4	2.5	-2.9
Blood Eosinophil Count	0.3	2.0	3.8	-0.8	-0.8	-1.7	0.4	-0.3	-1.7	-1.9	1.8	-1.9
Blood Platelet Count	2.8	33.0	90.6	5.2	7.3	-8.0	-6.5	-9.5	-1.0	0.0	2.2	-3.7
Blood Red Count	18.4	178.2	453.7	-15.6	-19.7	6.8	21.3	15.9	-5.6	-10.4	7.5	-4.9
Blood White Count	0.2	1.3	5.1	-0.5	-2.0	-0.6	1.5	-0.2	2.3	-0.0	0.3	-0.4
Heel T-Score	1.1	8.7	23.2	-1.2	-1.6	3.3	1.5	3.8	4.8	3.3	-2.1	2.9
BMI	1.2	7.0	18.4	-4.3	-3.5	1.6	2.9	3.2	0.8	-2.0	2.0	-1.6
Height	0.5	8.7	58.2	-0.4	0.1	-0.5	-1.2	-0.6	-7.6	-3.6	1.6	-1.6
Waist Hip Ratio (WHR)	0.6	2.9	6.5	0.7	0.9	2.2	0.7	0.9	1.2	2.2	-2.5	2.4
Systolic Blood Pressure	1.4	6.8	15.7	3.0	1.6	0.9	0.9	-0.9	2.9	3.7	-4.0	3.1
Smoking Status	0.2	0.4	0.8	0.9	-0.7	-0.1	-0.1	-0.5	0.8	0.8	-0.7	0.7
Allergy or Eczema	0.6	1.5	3.5	-1.9	-0.7	-0.4	0.9	0.9	-0.8	-1.0	1.8	-1.7
Cardiovascular Disease	0.2	0.8	2.3	-1.5	0.0	0.6	0.3	0.8	-1.2	-1.1	0.5	-1.0
Hypothyroidism (self reported)	1.9	4.4	10.5	2.0	1.0	1.0	0.5	0.4	2.7	3.2	-2.5	3.0
Respiratory disease	0.4	0.9	2.1	0.5	-0.2	-1.4	-1.2	-0.7	-1.2	-0.3	1.0	-0.8
Type 2 Diabetes (T2D) (2018)	2.1	4.0	9.5	1.1	-0.3	1.4	1.0	0.8	3.1	2.8	-2.5	2.7
Lung FEV1/FVC ratio	0.6	3.0	17.5	-0.8	-0.9	1.4	-0.2	0.8	4.2	1.9	-1.2	0.8
Lung FVC	0.9	4.7	12.8	1.1	0.5	-2.8	-2.3	-2.4	-3.6	-1.8	1.8	-1.6
Neuroticism	0.7	1.7	4.6	-0.2	0.5	-2.0	-0.5	-0.8	-1.0	-1.2	2.1	-1.8
Chronotype (morning person)	0.1	0.1	0.3	-0.5	-0.3	0.1	-0.6	-0.0	-0.0	-0.5	0.4	-0.2
Hair Pigment	3.0	84.5	179.6	12.0	4.3	1.4	-1.4	-4.1	9.9	13.4	-13.0	11.4
Tanning	0.7	8.1	16.3	-4.0	-4.0	2.0	3.1	3.3	-1.2	-2.7	2.2	-1.5
Hand grip strength (left)	1.4	3.7	16.2	-1.4	-0.2	0.1	-1.3	0.5	-4.0	-2.6	2.0	-1.5
Number of treatments/medications taken	0.0	0.1	0.2	-0.2	0.3	-0.2	-0.1	0.0	0.4	-0.0	0.4	-0.4
Average weekly spirits intake	0.3	0.4	0.9	0.8	0.1	-1.0	-0.6	-0.9	0.9	0.6	-0.0	-0.2
Sensitivity / hurt feelings	0.9	1.5	3.6	1.2	-0.4	0.3	0.1	-0.1	1.9	1.9	-1.5	1.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	2.0	0.5	-0.3	-0.5	-0.6	-0.2	-1.4	-0.7	0.6	0.1
Hearing difficulty/problems: Yes	0.1	0.2	0.5	-0.7	0.5	0.1	-0.3	0.1	0.3	-0.3	0.4	-0.5
Relative age of first facial hair	0.3	0.5	1.7	0.9	0.0	-0.8	-1.3	-1.1	0.4	0.5	-0.3	-0.1
Other serious medical condition/disability diagnosed by doctor	2.9	3.8	10.2	2.1	3.2	-1.6	-2.0	-2.3	2.0	1.7	-0.7	0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.7	-0.1	-0.0	-0.4	-0.8	-0.6	0.6	-0.1	-0.1	-0.4
Ever had hysterectomy (womb removed)	1.1	1.2	3.1	-1.2	-0.1	-1.1	-1.0	-0.4	0.2	-1.4	1.5	-1.8
Systolic blood pressure, automated reading	0.6	1.8	4.8	0.9	1.3	1.0	0.3	-0.3	1.5	1.7	-2.2	1.6
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.1	1.4	1.3	-0.6	-1.3	-1.0	0.6	1.2	-0.6	0.7
Angina	0.1	0.1	0.6	0.2	0.6	-0.3	0.8	-0.1	-0.0	-0.1	0.2	0.0
Medication for hormone replacement therapy	0.2	0.2	0.9	-0.2	-1.0	0.5	0.1	-0.1	0.2	-0.1	-0.6	0.3
Vitamin and mineral supplements	0.2	0.3	0.7	-0.2	0.8	-0.5	-0.2	-0.4	-0.5	-0.8	0.4	-0.6
Supplements: Zinc	2.0	2.2	5.2	-0.4	-0.8	1.7	1.9	1.4	2.3	1.1	-1.4	1.5
Medication: Co-codamol	0.8	1.0	2.3	-1.5	-1.4	1.0	1.1	1.2	-0.0	-0.9	0.4	-0.3
Medication: Metformin	2.7	3.8	8.8	1.8	0.7	0.8	-0.7	-0.0	2.6	3.0	-2.7	2.6
Diabetes (father)	0.5	0.6	2.5	0.7	-0.5	-0.5	-0.3	-0.3	1.6	1.2	-0.2	0.4
Diabetes (mother)	0.7	0.9	2.5	0.8	-0.1	0.4	0.0	-0.2	1.4	1.6	-1.4	1.1
Severe depression (siblings)	0.3	0.3	0.9	-0.7	-0.2	-0.0	0.3	0.4	-0.9	-0.6	0.7	-0.4
Pack years adult smoking proportion	0.5	0.7	3.1	-0.3	-1.8	0.5	1.0	0.8	1.1	0.0	0.1	0.5
Impedance of leg (right)	0.7	3.5	8.2	2.4	2.9	-1.7	-2.1	-2.3	-2.2	0.5	-0.6	0.2
Leg fat-free mass (left)	0.9	4.7	9.1	-2.8	-3.0	1.0	1.9	2.1	-2.0	-2.5	2.0	-1.6
Trunk fat percentage	0.7	3.0	7.6	-2.8	-0.8	0.1	0.7	1.1	-1.8	-2.4	1.9	-2.2
Hand grip strength (right)	1.7	4.5	20.5	-1.2	-0.0	-0.4	-1.2	0.0	-4.5	-3.0	2.2	-1.8
Townsend deprivation index at recruitment	2.8	3.9	9.1	-2.1	-3.0	0.0	0.9	1.3	-2.2	-2.4	2.4	-1.7
Current tobacco smoking	0.2	0.3	0.8	0.3	-0.9	-0.7	-0.3	-0.5	-0.2	-0.4	0.6	-0.3
Average weekly fortified wine intake	2.7	3.2	6.9	0.2	-1.2	1.9	1.6	1.5	2.6	2.3	-1.7	2.0
Maternal smoking around birth	0.2	0.4	1.1	0.6	-0.3	0.1	0.3	-0.3	0.7	0.5	-1.0	0.9
Fed-up feelings	0.8	1.4	4.1	0.2	-0.4	-2.0	-0.7	-1.2	-0.5	-1.0	1.8	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	1.9	0.2	-0.2	-0.9	-1.4	-0.7	-1.1	-0.9	0.9	-0.5
Relative age voice broke	1.6	2.5	8.9	0.7	0.5	-2.1	-3.0	-2.2	-0.9	-0.6	0.6	-1.4
Taking other prescription medications	0.2	0.2	0.8	0.4	0.1	-0.9	-0.5	-0.4	0.5	0.3	0.5	-0.3
Age when periods started (menarche)	0.9	2.1	4.7	2.2	1.8	-0.6	-1.6	-1.8	0.2	1.4	-1.6	1.0
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	3.5	-1.9	-1.1	0.4	-0.3	0.7	1.1	-0.9	0.9	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.7	-1.6	-1.0	1.1	0.2	1.6	0.8	-0.3	0.4	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	0.8	-0.4	-0.8	0.7	0.5	0.8	-0.9	-0.1	-0.3	0.4
Qualifications: CSEs or equivalent	1.6	2.1	5.5	1.1	2.0	-2.4	-0.8	-1.8	-1.2	-0.5	1.1	-1.2
Serious illness, injury or assault to yourself	1.5	1.9	6.7	1.1	-0.3	-2.6	-0.1	-1.9	-1.2	-1.0	1.3	-1.1
High blood pressure	0.1	0.2	0.5	-0.7	0.6	0.4	0.2	0.1	-0.5	-0.6	-0.1	-0.5
Hayfever, allergic rhinitis or eczema	0.9	1.9	3.9	-1.7	-1.1	-0.6	1.1	0.9	-1.3	-1.3	2.0	-1.8
Multivitamins +/- minerals	0.2	0.2	0.5	0.1	-0.3	0.7	0.0	0.4	0.5	0.7	-0.6	0.6
Stomach or abdominal pain in last month	1.8	2.3	6.0	0.7	-0.2	0.9	2.0	0.8	2.5	1.8	-1.5	1.7
Supplements: Glucosamine	1.5	1.9	8.0	-0.3	-1.1	1.4	0.2	1.2	2.8	1.1	-1.3	1.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.7	0.2	-1.3	0.6	0.4	0.4	-0.1	0.5	-0.3	0.5
Medication: Atenolol	0.3	0.4	1.0	0.0	-0.3	0.7	0.2	0.2	1.0	0.7	-0.8	0.6
Medication: Levothyroxine sodium	1.1	1.9	5.4	1.2	0.8	0.3	-0.6	-0.1	2.3	2.3	-1.4	1.6
Sitting height	0.2	1.7	11.0	-0.2	-0.8	0.1	0.4	0.6	-3.3	-1.3	1.0	-0.4
Chronic bronchitis/emphysema (father)	0.6	0.8	2.2	1.1	0.3	-1.3	-0.9	-1.5	-0.7	-0.3	0.3	-0.2
High blood pressure (mother)	1.2	1.7	5.5	2.3	1.6	-1.0	-0.7	-1.7	0.0	0.7	-1.2	0.9
Body mass index (BMI)	1.0	4.1	12.7	-3.6	-2.5	0.8	1.3	1.9	0.3	-2.0	2.0	-1.9
Impedance of leg (left)	1.2	5.7	14.0	2.5	3.7	-2.5	-3.0	-3.1	-2.5	0.2	-0.2	-0.4
Leg predicted mass (left)	0.9	4.5	9.3	-2.7	-3.0	1.0	1.9	2.1	-1.9	-2.4	1.9	-1.5
Trunk fat mass	0.9	3.8	8.4	-2.9	-1.3	0.1	0.6	1.1	-2.2	-2.7	2.2	-2.3
Waist circumference	0.7	2.6	8.4	-2.9	-1.9	1.3	1.1	2.0	0.0	-1.3	1.2	-1.1
Number of incorrect matches in round	0.4	0.7	1.6	-1.3	0.4	0.0	-0.9	0.4	0.5	-0.9	1.0	-0.9
Past tobacco smoking	2.0	3.7	10.7	-1.2	0.3	-1.2	-0.8	-0.2	-3.3	-2.6	2.5	-2.3
Alcohol usually taken with meals	0.5	0.8	2.1	0.1	-1.0	1.1	1.5	1.4	0.0	0.6	-0.5	0.8
Nervous feelings	0.4	0.8	2.3	1.0	0.1	-1.5	0.1	-0.7	-1.4	0.2	1.0	-0.7
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	5.2	-0.7	-0.2	-1.3	-0.1	0.1	-2.2	-1.7	2.3	-1.6
Hearing difficulty/problems with background noise	0.6	1.0	2.9	-1.7	-0.7	1.0	0.3	1.5	-0.7	-1.1	0.7	-0.5
Hair/balding pattern: Pattern 2	3.6	4.6	15.0	3.0	3.9	-2.1	-1.8	-2.9	-1.1	0.3	-0.7	0.3
Had menopause	1.6	2.0	4.6	-1.6	-0.7	-0.9	-1.1	-0.5	-0.8	-2.1	1.7	-2.1
Had other major operations	1.1	1.4	2.7	-0.3	-1.5	1.1	1.6	0.8	1.6	1.0	-1.1	0.8
Forced vital capacity (FVC)	1.5	5.7	25.8	0.5	0.6	-2.3	-1.7	-1.4	-5.1	-2.2	2.3	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.2	-1.0	-1.0	1.0	-0.3	1.1	1.0	-0.1	-0.1	0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.2	0.2	-1.1	-0.6	-0.8	-0.3	-0.8	-0.6	0.5	-0.2
Qualifications: None of the above	0.2	0.5	1.2	-0.6	0.7	-0.5	-0.1	-0.9	0.4	-1.1	0.4	-1.0
Financial difficulties in last 2 years	0.6	0.7	1.7	-0.6	-1.3	0.8	1.2	1.2	-0.8	-0.6	0.1	0.4
Mouth/teeth dental problems	0.5	0.8	2.2	-1.5	-1.4	0.2	-0.0	0.8	0.3	-0.8	0.9	-1.1
Heart attack	0.8	1.0	1.9	0.2	-0.8	1.1	1.3	0.9	1.4	0.8	-0.9	1.2
Allergy	0.6	1.4	2.2	1.3	1.3	0.2	-1.3	-1.2	1.5	0.9	-1.4	1.0
Pain all over the body in last month	0.6	0.7	1.5	-1.2	-0.8	-0.2	0.3	0.6	-0.3	-1.1	1.1	-1.0
Diabetes (self-reported)	1.3	1.9	4.3	0.5	-0.3	1.2	0.6	0.9	2.1	1.9	-1.6	2.0
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	3.2	0.3	-1.8	-0.0	-0.1	0.2	0.4	0.6	-0.2	0.4
Medication: Ramipril	0.1	0.1	0.3	0.5	0.5	-0.1	-0.1	-0.2	0.2	0.5	-0.3	0.2
Medication: Simvastatin	1.1	1.7	5.1	1.1	1.3	-0.2	-2.3	-1.3	1.5	1.0	-1.3	0.8
Fluid intelligence score	0.9	1.9	4.0	-0.9	0.5	-0.7	-2.0	-0.1	-2.0	-1.6	1.7	-1.5
Illnesses of siblings	2.2	3.0	9.9	-1.4	-2.4	1.6	3.1	2.4	1.0	-0.2	0.1	0.5
Neuroticism score	0.7	1.6	4.9	0.7	0.7	-2.2	-0.8	-1.2	-1.2	-0.5	1.6	-1.3
Weight	0.9	4.5	9.8	-3.1	-2.4	0.5	0.8	1.6	-2.0	-2.8	2.4	-2.2
Impedance of arm (right)	0.4	2.0	4.0	2.0	1.7	0.4	0.8	-0.2	-1.0	1.5	-1.9	1.8
Arm fat percentage (right)	0.7	3.0	9.2	-3.0	-1.6	0.7	1.4	1.8	-0.4	-1.9	1.7	-1.6
Trunk fat-free mass	0.5	3.0	5.7	-1.7	-2.4	-0.1	-0.1	0.7	-2.2	-2.4	2.2	-1.7
Hip circumference	0.7	3.1	7.4	-2.7	-2.4	0.7	1.1	1.7	-1.0	-1.8	1.9	-1.6
Time employed in main current job	0.6	0.7	1.7	0.8	1.0	-1.0	-1.1	-1.3	-0.8	-0.6	0.1	-0.2
Alcohol intake versus 10 years previously	0.5	0.7	1.5	-0.3	1.2	-0.8	-0.5	-0.9	0.7	-0.9	0.7	-1.0
Father’s age at death	1.3	1.8	7.2	0.7	-0.1	0.7	-0.1	-0.2	2.7	2.0	-1.7	1.1
Worrier / anxious feelings	1.0	1.9	3.7	-0.9	1.2	-1.4	-0.3	-0.2	-1.9	-1.6	1.9	-1.8
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	3.4	0.4	1.4	-1.8	-0.3	-1.1	-0.7	-0.2	1.7	-1.3
Falls in the last year	1.2	1.6	3.7	-1.6	-1.2	-0.7	-1.3	-0.0	0.3	-1.3	1.9	-1.6
Hair/balding pattern: Pattern 3	2.6	3.9	8.8	-1.3	-1.7	2.6	2.0	2.6	3.0	1.4	-1.0	1.3
Number of live births	0.6	0.9	2.9	-1.7	-0.8	0.4	-0.3	0.8	-0.7	-1.5	0.6	-0.9
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	9.6	0.1	0.1	-1.3	-0.9	-0.5	-3.1	-1.4	1.6	-1.4
Pulse rate	22.7	38.2	98.8	-3.2	0.7	-5.0	-3.4	-3.0	-9.9	-8.9	7.3	-7.5
Happiness	0.0	0.0	0.1	0.1	-0.2	-0.2	0.1	0.0	0.3	0.0	0.3	0.0
Noisy workplace	0.7	0.8	2.2	1.5	1.0	-1.2	-0.4	-1.4	0.2	0.5	-0.3	0.3
Qualifications: A levels/AS levels or equivalent	0.7	1.6	4.0	1.1	-0.1	1.5	0.2	1.0	-0.1	2.0	-1.3	2.0
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.2	-0.6	-1.2	1.4	1.5	1.8	1.1	0.9	-0.6	1.0
Mouth/teeth dental problems: Dentures	0.5	0.8	1.8	-1.3	-0.7	1.3	0.9	1.1	-0.1	-0.9	-0.3	0.3
Asthma	0.6	1.1	3.0	0.5	0.1	-1.6	-0.6	-0.7	-1.7	-0.8	1.3	-1.1
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	3.0	-0.8	-1.2	1.6	0.7	1.7	1.2	0.8	-0.7	1.1
Medication: Cholesterol lowering	1.2	1.8	3.5	1.5	1.9	-0.4	-1.2	-1.6	1.6	1.0	-1.4	0.9
Depression (self-reported)	0.2	0.2	0.6	0.8	-0.6	-0.7	-0.6	-0.4	-0.2	-0.0	0.5	0.2
Medication: Lansoprazole	0.8	1.0	3.2	0.2	0.7	-1.8	-0.5	-1.0	-0.1	-0.5	1.3	-1.2
Prospective memory result	0.5	0.6	1.8	1.1	1.4	-0.6	-0.2	-1.0	-0.7	0.3	-0.4	0.3
Lung cancer (father)	0.7	0.8	2.0	0.5	1.4	-1.2	-1.1	-1.4	-0.3	-0.3	0.0	-0.6
Illnesses of mother	0.8	1.0	3.3	-1.0	-1.8	-0.1	0.5	0.8	-0.8	-0.8	1.4	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	9.1	0.2	0.4	-1.1	-0.9	-0.7	-3.0	-1.3	1.4	-1.1
Pulse wave Arterial Stiffness index	1.0	1.1	2.9	-1.2	-1.1	0.5	1.1	1.0	-1.7	-1.1	0.7	-0.4
Impedance of arm (left)	0.6	2.9	6.6	2.6	2.0	0.3	0.5	-0.6	-1.0	2.0	-2.4	2.1
Arm fat mass (right)	0.9	3.7	9.5	-3.1	-2.2	0.5	1.0	1.6	-1.1	-2.3	2.0	-2.0
Trunk predicted mass	0.5	2.9	5.4	-1.6	-2.3	-0.1	-0.2	0.7	-2.1	-2.3	2.2	-1.6
Standing height	0.4	3.8	27.4	0.9	0.2	-0.7	-0.9	-0.9	-5.2	-1.7	0.7	-0.5
Length of working week for main job	1.0	1.1	2.2	-0.0	0.9	-1.5	-1.2	-1.3	-0.3	-0.7	1.2	-1.4
Exposure to tobacco smoke at home	1.2	1.3	4.0	-0.7	-2.0	1.4	1.3	1.0	1.2	0.4	-0.8	0.8
Breastfed as a baby	0.6	0.8	3.0	-0.2	-0.8	1.0	1.7	1.2	0.1	0.7	-0.4	0.7
Tense / ‘highly strung’	2.5	4.2	11.4	-2.0	-0.2	-1.4	0.6	0.4	-1.9	-2.8	3.4	-2.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.5	0.3	-0.6	-0.5	-0.5	-0.0	-0.7	-0.3	0.6	0.0
Hair/balding pattern: Pattern 4	0.6	1.4	3.3	-1.8	-1.6	1.1	1.0	1.8	-0.6	-0.7	0.9	-0.3
Birth weight of first child	1.1	2.0	6.0	1.3	1.5	-1.7	-2.5	-1.9	-0.8	-0.6	0.4	-0.5
Peak expiratory flow (PEF)	0.1	0.3	1.9	-0.2	-0.7	0.2	0.1	0.6	-1.4	-0.2	0.3	0.0
Pulse wave reflection index	0.6	0.8	1.6	0.1	-0.6	0.8	0.8	1.0	1.3	1.1	-0.7	1.0
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.0	0.7	0.6	-1.0	-0.8	-1.0	0.9	0.1	0.1	-0.0
Loud music exposure frequency	0.3	0.3	0.9	0.8	-0.5	0.3	0.2	-0.1	-0.6	0.2	-0.7	1.0
Qualifications: O levels/GCSEs or equivalent	0.3	0.6	1.8	-0.3	-1.1	1.3	-0.1	0.8	-0.6	0.2	-0.6	0.7
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	6.9	1.4	2.6	-1.0	-0.1	-1.5	1.1	1.2	-0.4	0.2
Blood clot in the leg (DVT)	1.3	1.6	4.6	1.9	0.5	-0.4	0.2	-0.6	1.3	2.1	-1.4	1.5
Medication: Paracetamol	0.3	0.6	1.6	-0.6	-1.2	0.6	1.3	1.0	-0.3	-0.3	0.3	0.1
Headache pain in last month	0.2	0.3	0.9	0.4	0.7	-0.8	-1.0	-0.6	-0.0	-0.1	0.4	-0.2
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	4.9	-1.7	-2.2	0.5	0.7	1.5	-0.5	-1.1	1.4	-0.9
Glaucoma (self-reported)	0.2	0.2	0.6	-0.3	-0.3	-0.1	0.6	0.0	-0.7	-0.7	0.3	-0.2
Gout (self-reported)	0.2	0.2	0.6	-0.8	-0.7	0.7	0.3	0.5	-0.1	-0.4	-0.2	-0.0
Hypothyroidism/myxoedema (self-reported)	2.3	4.5	11.5	2.4	0.7	0.3	0.2	-0.2	3.0	3.4	-2.4	2.8
Medication: Amlodipine	1.4	2.0	4.2	0.5	1.9	-1.8	-1.6	-2.0	-0.6	-0.9	0.9	-1.5
Medication: Ventolin 100micrograms inhaler	0.5	0.7	1.5	1.2	0.3	-0.9	-1.2	-1.2	-0.1	0.5	-0.6	0.2
Birth weight	0.2	0.5	2.1	0.2	-0.0	-0.3	-0.8	-0.5	-1.5	-1.2	0.3	-0.2
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.6	-0.3	-0.7	-0.2	-0.3	-0.5	-0.3	-0.4	0.1	-0.4
High blood pressure (siblings)	2.4	3.4	11.4	2.0	1.7	-0.9	-3.4	-2.3	1.2	1.7	-1.3	0.6
Forced vital capacity (FVC), Best measure	1.3	4.9	22.3	0.8	1.1	-2.1	-1.7	-1.6	-4.7	-2.0	1.8	-1.6
Body fat percentage	0.9	3.4	9.6	-3.1	-1.2	0.2	0.7	1.3	-1.4	-2.4	2.1	-2.2
Leg fat percentage (right)	0.8	3.0	8.5	-2.9	-1.4	-0.0	-0.1	0.9	-0.9	-2.3	2.1	-2.2
Arm fat-free mass (right)	0.8	4.0	7.5	-2.3	-2.3	-0.3	-0.3	0.7	-2.2	-2.7	2.6	-2.3
Exposure to tobacco smoke outside home	0.1	0.2	0.5	0.1	-0.4	-0.7	-0.3	-0.6	0.3	-0.2	0.0	-0.5
Comparative body size at age 10	0.5	1.5	3.7	-1.5	-1.3	1.5	-0.6	1.7	1.9	0.2	-0.3	0.6
Number of full brothers	0.2	0.3	0.7	-0.1	-0.3	0.6	-0.3	0.3	0.8	0.6	-0.7	0.4
Worry too long after embarrassment	0.8	1.3	3.5	0.9	0.9	-1.4	-1.3	-1.2	-1.9	-0.8	0.7	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.4	0.8	0.9	-0.5	-1.2	-0.8	-0.3	-0.0	-0.1	0.2
Wheeze or whistling in the chest in last year	1.2	2.2	4.6	-0.8	-1.3	-1.5	-0.1	-0.4	-1.4	-2.1	2.1	-2.0
Number of children fathered	0.6	0.6	2.1	0.9	0.1	-0.1	0.5	-0.5	1.5	0.9	-0.8	0.8
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	5.3	-1.8	-1.0	2.1	1.2	2.3	0.2	-0.5	-0.5	0.6
Age at first live birth	3.5	6.3	15.2	3.0	1.3	1.0	-0.5	-0.5	2.4	3.9	-3.4	3.4
Pulse wave peak to peak time	0.8	1.0	2.1	1.2	1.0	-0.5	-1.2	-1.0	1.4	1.0	-0.7	0.3
Health satisfaction	0.7	0.9	1.9	1.4	0.3	-0.5	-0.5	-0.9	1.1	1.3	-0.9	0.8
Shortness of breath walking on level ground	0.5	0.6	1.7	1.3	0.7	-1.0	-0.6	-1.0	0.4	0.6	-0.1	0.4
Qualifications: College or University degree	0.1	0.3	1.3	0.2	-0.1	0.3	-0.3	0.9	0.4	1.2	0.1	0.5
Eye problems/disorders: None of the above	1.0	1.2	3.0	-1.7	-1.1	0.4	0.5	1.2	-0.8	-1.4	1.0	-1.0
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	0.4	0.6	-0.2	-0.2	-0.3	-0.2	0.0	-0.1	0.2
Emphysema/chronic bronchitis	0.4	0.5	1.2	0.6	-0.8	0.7	-0.1	-0.1	-0.1	0.6	-1.1	1.0
Medication for pain relief, constipation, heartburn	1.0	1.7	3.1	-0.3	0.2	-1.6	-1.0	-1.1	-1.4	-1.8	1.6	-1.7
Neck or shoulder pain in last month	0.5	0.7	1.5	-1.2	-0.5	-0.4	0.2	0.2	1.0	-0.7	1.1	-1.1
Medication: Blood pressure	0.7	1.2	3.3	1.8	1.2	-0.0	0.1	-0.8	0.2	1.3	-1.5	1.3
Angina (self-reported)	0.1	0.1	0.4	0.3	0.7	-0.4	0.6	-0.3	-0.0	-0.1	0.3	-0.1
Migraine (self-reported)	1.2	1.5	5.2	-2.3	-0.1	1.3	1.1	1.9	-0.2	-0.9	0.8	-0.6
Medication: Ibuprofen	1.4	1.7	4.3	-1.4	-1.4	1.8	1.2	2.1	1.1	0.4	-0.3	0.8
Medication: Allopurinol	0.2	0.3	1.0	-0.6	-0.6	0.6	-0.2	0.3	1.0	0.2	-0.2	0.1
Medication: Omeprazole	1.9	2.2	6.2	-0.8	-0.7	1.7	2.5	1.6	2.1	1.0	-0.9	1.1
Medication: Seretide 50 evohaler	2.3	2.7	5.1	0.1	0.9	-2.1	0.1	-1.3	-2.3	-2.2	1.9	-1.9
Mean time to correctly identify matches	2.0	3.9	6.2	-0.5	2.2	-2.3	-1.3	-1.9	-2.0	-2.5	2.0	-2.2
Heart disease (mother)	0.5	0.6	2.9	0.8	1.7	0.2	-0.6	-0.2	0.3	0.7	-0.8	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	4.1	1.8	1.9	-1.6	-1.2	-2.0	-0.1	0.9	0.0	-0.3
Whole body fat mass	1.2	4.8	11.3	-3.4	-1.8	0.1	0.8	1.4	-2.1	-3.0	2.5	-2.6
Leg fat mass (right)	1.3	5.0	12.1	-3.5	-1.8	-0.0	0.3	1.2	-1.7	-3.0	2.8	-2.7
Arm predicted mass (right)	1.1	5.4	10.8	-2.9	-2.3	-0.2	-0.1	1.0	-2.7	-3.3	3.0	-2.7
Pulse rate, automated reading	36.0	116.4	309.8	-5.0	3.6	-9.0	-7.2	-5.5	-17.6	-14.8	12.3	-12.9
Alcohol intake frequency.	0.1	0.1	0.4	-0.1	-0.5	-0.2	0.5	-0.2	0.7	0.2	0.0	-0.1
Comparative height size at age 10	0.2	1.0	6.1	1.0	0.7	-0.5	0.3	-0.7	-2.5	-0.6	0.0	0.0
Number of full sisters	1.0	1.2	2.8	-1.7	-0.7	0.7	1.1	1.4	-1.1	-1.3	0.9	-0.6
Suffer from ‘nerves’	1.6	2.5	6.2	-0.6	0.3	-1.6	-0.3	-0.7	-2.5	-2.3	2.0	-2.0
Overall health rating	0.7	1.5	3.3	-0.1	1.0	-1.8	-1.3	-1.4	-0.7	-1.1	1.3	-1.5
Chest pain or discomfort	0.9	1.3	3.2	-0.7	-0.1	-1.2	0.4	0.1	-1.0	-1.7	1.8	-1.6
Had major operations	0.3	0.3	0.9	-0.1	-0.1	-0.8	-0.1	-0.4	-0.0	-1.0	0.8	-0.6
Age at last live birth	1.9	2.7	5.5	2.3	2.1	-0.4	-1.7	-1.4	0.5	2.0	-1.8	1.4
Family relationship satisfaction	0.4	0.5	1.8	-0.3	-1.3	0.1	-0.4	0.5	-0.6	-0.9	0.9	-0.1
Leg pain on walking	0.7	0.9	1.8	0.0	-0.7	1.1	0.7	0.8	1.1	0.8	-1.2	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.1	1.1	0.5	-0.7	-0.6	-1.0	0.2	0.7	-0.5	0.2
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.1	-1.0	-0.2	0.3	1.1	0.5	0.4	-0.5	0.4	-0.6
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.6	0.9	1.3	-1.1	-1.2	-1.2	-0.6	0.2	0.3	-0.6
Medication: Aspirin	2.2	2.9	6.7	1.6	0.5	1.0	-0.4	-0.1	2.0	2.6	-2.5	2.3
Supplements: Vitamin C	0.1	0.1	0.6	0.1	0.8	-0.2	0.5	0.0	0.5	0.3	0.2	-0.0
Knee pain experienced in last month	0.3	0.5	1.3	-0.9	-0.9	0.6	0.7	0.7	1.1	-0.1	-0.1	0.1
Hypertension (Self-reported)	0.1	0.2	0.8	-0.9	0.2	0.7	0.3	0.4	-0.3	-0.6	-0.2	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.7	-0.0	-0.1	0.8	1.0	0.7	1.3	1.2	-0.6	0.7
Illnesses of father: Heart disease	0.5	0.7	1.9	-1.3	-0.5	1.4	0.6	1.4	-0.3	-0.5	0.3	-0.1
Illnesses of siblings: Diabetes	0.3	0.3	0.9	0.7	0.2	-0.7	-0.3	-0.7	0.7	1.0	-0.3	0.2
Smoking status: Previous	2.2	3.2	9.0	0.7	0.0	1.4	1.3	0.6	3.0	2.4	-2.3	2.0
Forced expiratory volume in 1-second (FEV1), predicted	1.9	3.9	9.5	3.1	2.8	-1.6	-1.9	-2.6	-1.2	1.1	-1.1	0.7
Whole body fat-free mass	0.7	3.8	6.9	-2.2	-2.6	0.2	0.5	1.1	-2.2	-2.6	2.4	-1.9
Leg fat-free mass (right)	0.7	3.6	6.4	-2.4	-2.5	0.7	1.5	1.6	-1.9	-2.3	1.9	-1.5
Arm fat percentage (left)	0.7	3.0	9.2	-3.0	-1.8	0.8	1.4	1.8	-0.4	-1.8	1.6	-1.6
Average weekly red wine intake	2.2	3.3	7.5	1.8	-0.3	0.8	-1.2	-0.3	2.3	2.7	-2.5	2.2
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.5	-0.8	0.1	-0.0	-1.2	0.3	-1.1	-1.2	0.9	-0.7
Mood swings	0.5	1.0	2.8	1.7	0.5	-1.1	-0.3	-1.1	0.9	1.4	-0.2	0.6
Loneliness, isolation	1.5	2.1	5.5	-1.3	-0.1	-0.9	-0.2	0.2	-1.9	-1.9	2.3	-1.8
Long-standing illness, disability or infirmity	1.2	1.8	5.4	1.3	1.9	-0.9	-0.5	-1.2	2.3	1.6	-0.7	0.5
Ever had bowel cancer screening	1.3	1.6	3.7	-1.5	0.3	-0.8	-1.0	0.1	-0.7	-1.5	1.8	-1.9
Diabetes diagnosed by doctor	1.5	2.5	5.4	1.1	0.4	0.9	0.4	0.4	2.3	2.3	-2.1	2.2
Ever had stillbirth, spontaneous miscarriage or termination	3.0	3.2	6.7	-1.5	-1.9	2.6	1.8	2.4	2.0	0.4	-1.1	1.4
Friendships satisfaction	0.7	0.9	1.9	-0.2	0.1	-1.0	-0.9	-0.3	-1.4	-1.1	1.4	-0.9
Qualifications: nursing, teaching	0.2	0.2	1.0	0.1	1.0	-0.1	-0.1	0.1	-0.8	-0.2	0.6	-0.1
Commuting to job workplace: Walk	0.1	0.1	0.2	0.4	0.0	-0.4	-0.0	-0.2	0.3	-0.1	0.2	-0.1
Eye problems/disorders: Cataract	0.5	0.5	1.7	1.3	1.0	-0.7	0.0	-0.9	-0.6	0.3	-0.4	0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.4	1.2	0.3	-0.1	0.1	-0.1	-0.4	1.0	-0.6	1.0
Medication for cholesterol	0.3	0.5	2.8	0.8	0.2	-0.1	1.7	0.4	-0.3	0.6	0.1	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.4	4.9	-1.4	0.3	-0.9	-1.3	-0.3	-2.2	-2.2	1.9	-2.1
Back pain experienced in last month	0.1	0.1	0.5	-0.6	-0.1	-0.1	0.2	-0.1	0.1	-0.7	0.4	-0.4
Mineral and other dietary supplements	1.4	1.8	6.3	-1.3	-1.1	-0.0	1.0	0.8	-2.5	-1.7	1.3	-1.0
Breast cancer (self-reported)	0.4	0.5	1.5	0.4	0.3	-1.2	0.0	-1.1	-0.3	-0.3	0.5	-0.8
Asthma (self-reported)	0.6	1.1	2.9	0.5	-0.0	-1.6	-0.7	-0.8	-1.7	-0.9	1.2	-1.1
Osteoporosis (self-reported)	0.6	0.7	1.7	1.3	-0.1	-1.2	-1.2	-1.1	-0.6	0.5	-0.0	0.0
Osteoarthritis (self-reported)	0.2	0.2	0.5	-0.7	0.2	0.5	0.0	0.7	0.7	-0.0	0.0	0.2
Medication: Aspirin	1.8	2.3	5.2	1.4	0.5	0.8	-0.6	-0.3	1.8	2.3	-2.2	2.0
Medication: Gliclazide	0.8	0.9	1.9	1.4	0.2	-0.3	-0.5	-0.4	1.3	1.4	-0.9	1.3
Illnesses of father: None of the above (group 1)	0.8	1.0	1.9	-1.3	-0.8	-0.4	0.9	0.5	-0.9	-1.4	1.1	-1.2
Smoking status: Current	0.2	0.3	0.8	0.4	-0.5	-0.9	-0.6	-0.7	-0.3	-0.4	0.7	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	7.9	-1.3	0.5	-1.5	-0.9	-0.4	-2.8	-2.4	2.4	-2.4
Whole body water mass	0.6	3.7	6.9	-2.2	-2.6	0.2	0.5	1.2	-2.2	-2.5	2.3	-1.8
Leg predicted mass (right)	0.7	3.5	6.4	-2.4	-2.5	0.7	1.6	1.6	-1.8	-2.3	1.9	-1.5
Arm fat mass (left)	0.8	3.4	9.4	-3.1	-2.0	0.5	0.9	1.5	-1.0	-2.2	1.9	-1.9
Number of self-reported non-cancer illnesses	0.4	0.7	3.2	-0.0	1.8	-1.0	-0.4	-0.8	0.1	-0.2	0.7	-0.9
Average weekly champagne plus white wine intake	1.5	2.1	6.1	-1.6	-1.5	2.2	1.5	2.5	0.4	0.1	-0.5	0.6
Miserableness	0.5	0.9	2.4	1.1	1.0	-1.6	-1.0	-1.1	-0.3	0.5	0.8	-0.3
Guilty feelings	0.6	0.8	3.1	-0.5	-0.2	-0.7	0.1	0.3	-1.8	-1.1	1.3	-0.9
Wears glasses or contact lenses	0.1	0.1	0.4	-0.3	-0.2	0.2	-0.1	0.1	-0.6	-0.3	-0.1	0.1
Ever taken oral contraceptive pill	1.1	1.2	3.3	1.0	0.1	1.0	-0.1	0.3	0.9	1.4	-1.8	1.8
Hearing aid user	2.5	2.9	7.6	-1.5	0.4	-1.8	-0.3	-0.7	-0.7	-2.0	2.7	-2.8
Mother’s age at death	1.9	2.4	5.4	-1.4	-2.3	2.0	1.7	2.3	1.0	0.6	-0.4	0.7
Financial situation satisfaction	1.7	2.1	6.0	2.4	1.4	-0.5	-1.4	-1.6	-0.4	1.1	-1.6	1.6
Tinnitus: Yes, now most or all of the time	0.9	1.0	3.2	1.1	0.1	0.9	0.3	0.3	0.4	1.1	-1.5	1.8
Commuting to job workplace: Public transport	0.3	0.3	0.9	1.0	0.5	-0.1	0.4	-0.2	0.4	0.7	-0.6	0.8
Eye problems/disorders: Glaucoma	0.0	0.0	0.1	0.1	-0.2	-0.1	0.3	-0.2	-0.2	-0.4	-0.1	0.0
Medication: Blood pressure	0.6	1.2	3.2	-1.8	-0.9	1.6	-0.3	1.3	1.4	-0.2	-0.5	0.0
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.6	-0.7	-0.1	-0.3	-0.5	-0.3	0.6	-0.8	0.4	-0.8
Supplements: Fish oil (including cod liver oil)	1.5	2.0	4.3	1.5	1.5	-0.8	-1.7	-1.4	2.1	1.5	-0.9	0.5
High cholesterol (Self-reported)	0.3	0.5	1.3	-0.5	0.8	-0.4	-1.1	-0.6	-0.5	-0.7	0.4	-0.8
Medication: Bendroflumethiazide	0.2	0.3	0.9	0.0	0.5	0.8	-0.1	0.3	0.7	0.4	-1.0	0.7
Medication: Paracetamol	0.4	0.6	2.8	-0.2	-1.3	0.5	1.7	0.8	-0.1	0.1	0.1	0.4
Medication: Lisinopril	0.5	0.7	1.4	1.1	0.2	0.0	0.1	-0.3	1.0	1.2	-1.2	1.1
Medication: Atorvastatin	1.2	1.4	4.7	-0.5	1.1	-0.7	-0.6	-0.8	-2.2	-1.6	1.1	-1.2
Illnesses of father: High blood pressure	0.6	0.7	4.2	0.1	2.1	-0.4	-1.0	-0.7	0.4	0.3	-0.0	-0.4
Alcohol drinker status: Never	0.3	0.4	1.3	-0.2	0.4	0.7	1.1	0.9	0.0	0.3	-0.3	0.4
Ever smoked	2.2	3.9	10.0	1.7	-0.5	1.0	0.3	-0.0	3.2	2.8	-2.6	2.5
Basal metabolic rate	0.7	4.1	7.5	-2.4	-2.5	0.2	0.6	1.2	-2.4	-2.7	2.4	-2.0
Leg fat percentage (left)	0.9	3.1	7.7	-2.8	-0.9	-0.5	-0.6	0.5	-0.9	-2.4	2.4	-2.5
Arm fat-free mass (left)	0.8	4.2	8.3	-2.5	-2.2	-0.2	-0.3	0.7	-2.2	-2.9	2.7	-2.4
Number of operations (self-reported)	1.0	1.4	4.9	-1.7	-2.2	0.8	1.0	1.3	1.2	-0.6	0.3	-0.3
Average weekly beer plus cider intake	0.6	0.9	2.5	0.8	0.9	-1.3	0.2	-0.8	-1.6	-0.4	1.0	-0.8
Irritability	0.8	1.3	3.9	-0.0	-0.6	-2.0	-0.3	-0.8	-0.3	-0.9	1.9	-1.6
Risk taking	0.4	0.6	2.0	-0.7	-0.2	-0.8	-0.2	0.3	-0.4	-1.1	1.4	-1.0
Ever had prostate specific antigen (PSA) test	0.7	0.9	2.2	-0.2	1.5	-0.9	-1.1	-0.8	0.1	-0.6	0.9	-1.1
Fractured/broken bones in last 5 years	1.1	1.5	3.5	0.5	-0.6	-1.9	-1.5	-1.5	-1.2	-0.7	1.1	-1.1
Age started oral contraceptive pill	0.3	0.4	1.0	-0.5	0.8	-0.0	-1.0	-0.3	-0.4	-0.7	0.4	-0.5
Diastolic blood pressure, automated reading	3.6	11.2	37.4	-3.2	-0.8	-0.9	0.0	0.0	-6.1	-5.2	3.2	-3.8
Ever depressed for a whole week	0.8	0.9	2.8	0.7	-0.8	0.9	0.1	0.3	0.8	0.8	-1.5	1.7
Unable to work because of sickness or disability	0.7	1.0	2.5	-1.1	0.0	-0.9	-0.1	-0.2	-0.6	-1.3	1.4	-1.6
Commuting to job workplace: Cycle	0.8	0.9	2.6	0.8	1.3	-1.1	-1.6	-1.4	-0.7	-0.2	0.2	-0.3
Myopia	0.2	0.3	1.0	0.8	-0.8	-1.0	0.1	-0.5	-0.3	0.4	0.2	-0.2
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.7	0.2	-1.3	-0.1	0.1	0.4	0.4	0.5	0.3	0.3
Cholesterol lowering medication	1.7	2.5	9.7	-0.8	0.9	-1.2	-3.1	-1.1	-1.3	-1.5	1.3	-1.8
Medication: Omeprazole (e.g. Zanprol)	1.9	2.3	5.2	-0.5	-0.6	1.7	2.3	1.6	2.2	1.3	-1.2	1.4
Pain experienced in last month	0.6	1.0	2.1	0.2	-0.8	1.4	0.9	1.1	0.1	0.8	-1.2	1.4
Supplements: Calcium	0.3	0.4	0.7	-0.2	-0.7	0.8	0.3	0.8	0.6	0.7	-0.2	0.5
Basal cell carcinoma (self-reported)	0.4	0.5	1.1	-1.0	-0.2	0.6	0.6	0.8	-1.0	-0.5	0.4	-0.5
Heart attack/myocardial infarction (self-reported)	0.8	1.0	1.6	0.1	-0.9	1.2	1.3	1.0	1.2	0.7	-0.9	1.2
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	4.9	1.9	0.4	-0.4	0.2	-0.5	1.4	2.2	-1.4	1.5
Heart disease (siblings)	1.1	1.3	3.7	-1.2	-0.0	-0.2	-0.9	0.1	-1.9	-1.7	1.1	-1.4
Alcohol drinker status: Previous	0.6	0.7	1.1	-0.2	1.0	-0.8	-1.0	-1.1	-0.7	-0.7	0.8	-1.0
Pack years of smoking	0.3	0.5	2.2	-0.2	-1.5	0.3	0.8	0.5	1.0	-0.0	0.0	0.5
Impedance of whole body	0.6	3.1	8.7	2.6	2.9	-1.1	-1.1	-1.8	-2.0	1.0	-1.4	0.8
Leg fat mass (left)	1.2	4.6	10.8	-3.3	-1.6	-0.3	0.1	0.9	-1.7	-3.0	2.8	-2.8
Arm predicted mass (left)	0.9	4.6	9.1	-2.5	-2.4	-0.3	-0.1	0.8	-2.5	-3.0	2.8	-2.4