TWAS hub - PRKRIP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0610	0.0340	1.7e-02	0.026	0.001	0.039	0.012	0.034	3.6e-04	2.4e-01	1.4e-05	1.3e-02	4.6e-05
2	GTEx	Adipose Subcutaneous	0.0820	0.0330	6.6e-03	0.011	NA	0.015	NA	0.016	4.2e-02	NA	2.0e-02	NA	1.6e-02
3	GTEx	Adipose Visceral Omentum	0.1720	0.0760	4.8e-03	0.073	NA	0.070	NA	0.029	1.2e-04	NA	1.8e-04	NA	1.2e-02
4	GTEx	Breast Mammary Tissue (Male)	0.0741	0.0768	1.9e-01	0.193	NA	0.124	NA	0.180	3.0e-05	NA	8.5e-04	NA	5.8e-05
5	GTEx	Breast Mammary Tissue (Female)	0.1359	0.0726	3.6e-02	-0.009	NA	-0.010	NA	-0.001	8.0e-01	NA	9.2e-01	NA	3.4e-01
6	GTEx	Cells EBV-transformed lymphocytes	0.1690	0.0700	7.0e-03	0.000	NA	0.069	NA	0.014	3.2e-01	NA	2.9e-03	NA	1.1e-01
7	GTEx	Cells Transformed fibroblasts	0.1940	0.0460	3.5e-07	0.144	NA	0.142	NA	0.145	5.9e-11	NA	8.1e-11	NA	5.3e-11
8	GTEx	Esophagus Gastroesophageal Junction	0.2730	0.0920	5.9e-04	0.048	NA	0.021	NA	0.034	7.9e-03	NA	5.9e-02	NA	2.1e-02
9	GTEx	Esophagus Muscularis	0.1250	0.0510	1.9e-03	-0.004	NA	0.002	NA	0.000	7.9e-01	NA	2.2e-01	NA	3.3e-01
10	GTEx	Lung	0.0908	0.0348	1.2e-03	-0.003	NA	0.009	NA	0.001	8.4e-01	NA	6.1e-02	NA	2.8e-01
11	GTEx	Nerve Tibial	0.1828	0.0571	8.4e-05	0.069	NA	0.108	NA	0.093	1.4e-05	NA	4.3e-08	NA	3.9e-07
12	GTEx	Skin Sun Exposed Lower leg	0.1000	0.0390	1.5e-03	-0.003	NA	0.001	NA	0.002	9.6e-01	NA	2.5e-01	NA	2.0e-01
13	GTEx	Testis	0.4720	0.0860	3.9e-09	0.113	NA	0.283	NA	0.276	1.0e-05	NA	5.5e-13	NA	1.1e-12
14	GTEx	Thyroid	0.2570	0.0600	1.3e-08	0.239	NA	0.211	NA	0.226	3.0e-18	NA	4.5e-16	NA	3.2e-17
15	METSIM	Adipose	0.1242	0.0330	1.1e-10	0.004	0.078	0.060	0.076	0.044	7.8e-02	1.1e-11	2.5e-09	1.7e-11	2.8e-07
16	ROSMAP	Brain Pre-frontal Cortex	0.0588	0.0303	1.5e-02	0.037	0.000	0.010	0.004	0.008	1.2e-05	2.7e-01	1.7e-02	8.3e-02	3.2e-02
17	YFS	Blood	0.1145	0.0235	0.0e+00	0.091	0.091	0.099	0.096	0.098	4.2e-28	3.7e-28	1.2e-30	7.4e-30	2.9e-30
18	TCGA	Colon Adenocarcinoma	0.0750	0.0420	1.5e-03	0.032	0.066	0.047	NA	0.048	6.1e-03	1.2e-04	9.9e-04	NA	9.5e-04
19	TCGA	Prostate Adenocarcinoma	0.0375	0.0228	9.9e-03	0.027	0.007	0.017	NA	0.012	6.4e-04	5.6e-02	5.7e-03	NA	1.7e-02
20	TCGA	Thyroid Carcinoma	0.0660	0.0360	3.2e-03	0.045	0.026	0.025	NA	0.033	3.5e-05	1.3e-03	1.5e-03	NA	3.3e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20
Chronotype (morning person)	3.9	9.1	42.8	-5.3	-3.3	-2.4	-3.9	-4.3	-0.7	-3.4	-0.4	-1.9	-6.5	-0.2	0.3	-0.5	-3.6	-3.4	1.1	-0.4	2.9	2.9	-0.9
Alzheimer’s Disease (in mother)	3.4	4.0	13.3	1.4	1.4	1.3	3.0	0.9	3.0	2.5	2.6	1.7	3.6	0.3	1.1	0.1	2.9	3.2	-0.6	-0.9	-1.1	-1.8	-1.1
Type 2 Diabetes (T2D) (2018)	3.1	5.9	18.2	4.2	0.6	-0.0	3.2	0.2	3.0	1.7	1.4	-0.7	4.3	-1.7	-0.4	-0.5	3.1	2.7	-0.6	-2.5	-3.6	-2.6	-3.2
Diabetes diagnosed by doctor	3.0	5.0	16.2	2.9	1.3	0.6	3.4	0.2	2.8	2.2	0.8	0.2	4.0	-1.2	0.3	-0.2	3.5	2.2	-0.4	-2.4	-3.2	-2.6	-2.5
Friendships satisfaction	3.0	3.7	9.6	-0.1	2.9	2.5	2.4	-0.1	1.5	3.1	1.5	1.7	0.7	2.6	1.4	3.1	2.7	2.1	1.3	1.3	-0.1	1.1	1.7
Diabetes (mother)	2.6	3.3	11.4	1.5	2.9	1.9	3.1	1.2	1.0	3.2	0.0	1.9	2.2	1.2	-0.1	2.3	3.4	1.3	0.5	-0.2	-1.3	-0.5	0.2
Irritability	2.5	4.3	13.2	-0.7	3.0	2.7	2.2	1.5	0.5	2.7	2.0	3.1	1.1	2.6	1.9	3.6	2.3	0.6	0.9	1.5	0.1	1.0	2.2
Diabetes (self-reported)	2.4	3.6	14.3	2.4	0.8	0.3	2.5	0.6	2.4	1.5	-0.2	-0.3	3.8	-1.7	-0.4	-0.4	2.7	2.2	-0.1	-2.0	-3.0	-1.9	-2.3
Family relationship satisfaction	2.3	2.8	8.7	0.3	2.0	2.0	1.4	1.5	0.8	2.0	1.2	2.1	0.8	2.6	0.2	2.9	1.3	2.3	0.6	2.3	-0.1	1.0	1.9
Lung cancer (father)	2.2	2.6	7.5	-2.7	-0.0	-1.2	-1.9	1.6	-2.2	-1.2	-0.9	0.4	-1.2	0.6	0.9	0.8	-1.7	-1.4	1.2	1.4	2.7	2.4	2.0
Long-standing illness, disability or infirmity	2.2	3.3	9.8	2.8	2.0	1.5	1.5	0.5	1.1	2.1	1.1	2.1	-0.3	3.0	0.3	3.1	1.5	1.9	-1.3	2.2	-1.4	-0.9	1.9
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	6.8	1.3	-1.5	-1.8	-0.9	-1.6	-0.5	-1.4	0.3	-2.6	0.9	-2.2	-1.2	-2.4	-0.4	-0.2	-1.1	-1.9	-0.6	-1.3	-2.2
Supplements: Zinc	2.0	2.2	7.2	-0.7	2.0	2.7	1.7	0.2	1.5	2.2	0.7	2.4	1.0	1.8	0.8	1.3	2.2	1.8	-0.0	0.1	-1.0	-0.7	0.7
Medication: Levothyroxine sodium	2.0	3.4	11.0	1.5	2.5	1.4	0.4	1.3	0.0	1.5	2.1	2.1	-0.1	3.3	-1.1	2.4	0.6	2.1	-1.4	2.9	0.7	-0.5	3.1
Comparative body size at age 10	2.0	5.6	18.1	-0.9	0.7	-0.6	-2.5	1.9	-1.6	-0.9	1.6	1.1	-1.8	3.0	0.9	2.7	-2.4	-1.6	1.5	3.9	3.5	4.1	4.3
Hypothyroidism (self reported)	1.9	4.4	12.8	2.8	3.0	2.1	0.8	1.7	0.3	1.9	2.0	1.8	0.4	3.6	-1.5	2.5	1.0	2.3	-2.4	2.7	0.0	-1.5	3.1
Medication: Metformin	1.9	2.7	10.4	1.8	1.4	0.7	2.7	0.2	1.8	2.1	1.5	1.0	3.2	-0.2	1.3	0.4	2.6	2.1	0.4	-0.9	-1.9	-1.2	-1.3
Exposure to tobacco smoke outside home	1.8	2.3	7.2	-2.5	-2.1	-1.5	-2.0	-0.3	-1.9	-2.4	0.7	-0.0	-1.6	0.1	1.0	-0.2	-2.7	-1.4	1.1	-0.6	1.6	1.7	-0.0
Smoking status: Previous	1.8	2.7	9.1	1.9	1.8	1.0	2.7	-0.1	1.2	2.8	0.9	2.8	0.8	1.3	0.9	1.4	3.0	0.7	-0.3	-0.1	-2.1	-1.6	-0.3
Wears glasses or contact lenses	1.8	2.1	8.6	-0.7	1.4	0.5	0.7	1.6	0.9	1.2	1.0	2.9	-0.0	2.5	0.3	2.4	0.4	0.6	1.3	1.9	1.2	1.3	1.8
HbA1C	1.7	1.8	6.5	0.8	1.9	0.5	2.4	-1.1	1.6	2.1	2.0	0.6	0.6	0.8	0.9	1.0	2.6	1.3	0.2	-0.7	-1.1	-1.0	0.0
Other serious medical condition/disability diagnosed by doctor	1.7	2.3	7.5	2.0	2.1	0.1	2.7	-1.3	2.1	2.5	1.0	0.9	-0.5	1.3	1.4	1.6	2.6	0.7	0.4	-0.7	-0.1	-0.7	0.2
Hypothyroidism/myxoedema (self-reported)	1.7	3.3	10.6	2.7	2.1	1.3	0.5	1.2	-0.2	1.5	1.5	1.8	-0.1	3.3	-1.8	2.2	0.7	1.9	-2.3	2.4	-0.0	-1.5	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	4.5	-1.1	-1.6	0.4	-1.1	-2.0	-1.5	-1.6	-1.6	-0.6	-2.0	-1.4	-2.1	-1.7	-1.3	-1.3	-1.4	-1.2	-0.3	-1.2	-1.0
Breast Cancer	1.6	3.8	11.6	-1.9	-1.5	0.5	0.5	-1.6	-0.3	-1.0	1.5	-2.7	3.1	-2.7	2.6	-2.7	0.0	-1.7	0.3	-3.4	0.8	-0.6	-3.4
Crohns Disease (2012)	1.6	2.6	6.6	-2.4	-1.3	-2.4	-1.5	-1.2	0.1	-1.5	-1.2	0.2	-2.5	-1.1	1.1	-0.9	-1.6	-2.6	2.3	-0.3	1.8	2.0	0.0
Severe depression (siblings)	1.6	1.7	7.2	1.2	1.1	1.3	1.9	-0.3	1.6	1.4	-1.2	0.5	1.3	-0.6	0.3	0.2	1.8	0.8	-1.9	-0.5	-1.8	-2.7	-0.6
Mouth/teeth dental problems	1.6	2.4	6.3	1.5	2.2	1.9	2.1	-0.5	2.2	2.3	1.6	0.1	1.0	1.1	-0.1	0.9	2.3	2.5	-0.6	1.2	-1.3	-1.4	0.9
Qualifications: College or University degree	1.5	4.6	15.4	1.2	2.7	3.1	1.2	2.1	0.1	2.4	1.3	0.9	0.8	3.3	-0.4	2.6	1.4	3.5	-1.1	3.9	1.0	0.0	3.1
Mouth/teeth dental problems: Loose teeth	1.5	1.8	8.6	-0.1	-1.3	-1.2	0.3	-1.7	0.9	-0.5	0.4	-1.0	-0.1	-2.1	-0.0	-1.2	0.3	-1.6	-0.1	-2.9	-1.1	-1.1	-2.8
Medication for pain relief, constipation, heartburn	1.5	2.5	10.5	1.2	1.9	2.4	2.0	0.9	1.4	2.2	0.9	-0.8	3.2	0.8	1.0	0.1	2.2	2.4	-1.1	0.3	-0.7	-1.8	0.2
Hearing aid user	1.5	1.7	3.7	1.2	-1.9	-0.3	-1.9	-0.8	-1.6	-1.9	-0.6	-1.6	-1.1	-0.7	-0.8	-1.1	-1.8	-1.8	-1.9	-0.5	-0.4	-0.8	-0.8
Alzheimer’s Disease (including proxy)	1.4	2.1	9.5	0.9	0.8	0.4	2.2	0.7	3.1	1.8	2.1	1.7	1.8	0.4	1.3	0.9	1.9	1.9	0.4	-0.8	-0.5	-0.2	-0.6
Body Mass Index (BMI) (2010)	1.4	2.0	5.6	-1.1	-2.0	-1.9	-1.0	0.1	-0.7	-1.7	-1.6	-1.9	-0.5	-2.3	-0.5	-2.4	-1.2	-2.0	0.8	-1.6	0.0	0.0	0.0
Mean Putamen Volume	1.4	1.6	5.4	-2.2	-0.7	0.1	-1.0	-0.8	0.5	-1.0	2.3	0.3	-2.1	0.6	1.8	0.4	-1.3	-1.1	1.4	0.2	1.1	1.7	0.0
Fasting Glucose	1.4	1.7	6.8	1.0	-0.7	1.1	-0.1	1.2	-0.1	-0.1	-1.1	-1.9	2.0	-0.8	-2.0	-0.5	0.4	0.6	-2.6	-0.4	-1.9	-2.3	0.0
Type 2 Diabetes (T2D) (2012)	1.4	1.6	5.8	-0.4	2.3	0.5	1.3	2.0	0.8	2.0	-0.7	1.3	1.9	0.7	1.1	1.0	2.4	-0.0	1.1	-0.3	0.0	0.0	0.0
Alcohol intake versus 10 years previously	1.4	2.2	7.7	0.3	-1.3	0.3	-0.2	0.2	-0.8	-0.7	-1.9	-1.1	0.5	-0.9	-2.4	-1.2	-0.1	-0.3	-2.3	-1.5	-2.8	-2.5	-2.4
Qualifications: A levels/AS levels or equivalent	1.4	3.0	8.0	1.9	1.9	2.8	0.3	2.5	0.8	1.4	1.2	1.4	1.7	2.1	-1.2	0.7	0.6	2.6	-1.6	2.4	-1.0	-1.3	2.4
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	7.8	-0.7	-1.5	-0.3	-2.1	0.1	-2.8	-1.9	-1.0	-1.9	-1.4	0.0	-1.0	-0.2	-2.5	-0.9	-0.7	0.9	0.8	0.8	0.6
Glaucoma (self-reported)	1.4	1.7	4.1	-1.6	0.3	0.8	1.8	-0.2	1.8	1.2	0.8	1.0	1.8	-0.3	1.1	-0.5	1.9	-0.1	-0.3	-1.8	-1.2	-1.8	-2.0
Smoking status: Current	1.4	2.2	5.8	-2.2	-1.2	-1.5	-1.4	-0.8	-0.2	-1.8	-2.3	-1.5	-1.2	-2.4	0.0	-0.9	-1.6	-2.3	0.7	-0.7	1.8	1.2	-0.4
Risk taking	1.4	2.1	9.1	-1.0	1.1	1.1	3.0	-0.8	1.4	2.3	-0.1	1.5	1.0	0.4	0.7	-0.1	2.8	0.5	0.1	-1.7	-0.9	-1.8	-1.6
Irritable Bowel Disease (IBD)	1.3	3.2	8.9	-1.4	-2.1	-3.0	-2.1	-1.1	-1.3	-2.2	-1.1	-1.7	-2.3	-1.5	0.4	-0.9	-2.3	-1.8	1.9	0.4	1.7	2.6	-0.4
Ulcerative Colitis (UC)	1.3	2.5	5.8	-1.5	-2.3	-1.9	-2.3	-1.4	-1.7	-2.4	-1.0	-1.8	-2.3	-1.2	-0.3	-1.2	-2.4	-1.1	0.4	0.2	1.1	1.5	-0.7
Ulcerative Colitis	1.3	1.9	7.1	-0.7	-1.7	-2.3	-1.8	-1.9	-1.0	-1.7	-0.7	-1.0	-2.7	-0.7	0.3	-1.3	-1.8	-1.9	0.7	-0.0	0.0	0.0	0.0
Diabetes (father)	1.3	1.6	6.2	1.4	0.8	0.7	1.8	0.4	1.2	1.3	-0.2	-0.8	1.9	-0.7	-0.4	-0.0	2.0	1.2	-0.8	-1.1	-2.5	-1.8	-1.1
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	5.5	0.4	0.1	-0.1	-1.1	2.3	-2.1	-0.7	1.6	0.1	0.4	1.1	-0.4	1.2	-1.2	1.5	-0.7	2.1	0.4	0.7	1.7
Medication: Ramipril	1.3	1.7	4.2	1.6	1.4	1.2	1.8	-0.2	0.3	1.8	2.0	1.4	0.3	1.2	0.4	1.1	1.8	1.2	-1.0	0.1	-2.1	-1.4	0.1
Exposure to tobacco smoke at home	1.3	1.5	3.9	-2.0	-1.6	-1.7	-0.9	-0.4	-0.4	-1.6	-0.0	-0.7	-0.2	-1.5	0.7	-1.4	-1.1	-0.4	1.8	-1.3	1.2	1.4	-1.1
Comparative height size at age 10	1.3	7.3	34.8	0.0	2.2	1.9	-0.1	5.9	-0.8	0.9	2.7	3.4	3.0	3.8	2.2	3.7	-0.6	2.9	0.5	3.6	1.0	2.0	3.8
Average weekly red wine intake	1.3	1.9	8.9	1.0	2.1	1.8	1.5	0.3	1.2	1.8	1.4	-1.1	1.8	0.1	-0.3	0.8	1.9	3.0	-0.4	1.5	0.2	-0.7	1.0
Breast cancer (self-reported)	1.3	1.5	5.4	1.1	0.6	0.7	-0.0	0.6	-1.5	0.8	-0.5	1.9	-1.6	2.3	-1.3	1.0	0.2	1.4	-1.2	1.6	-1.5	-0.9	1.1
Medication: Omeprazole (e.g. Zanprol)	1.3	1.5	8.2	-1.2	-0.9	-2.2	-1.6	-0.7	-0.3	-1.4	-0.2	-0.5	-1.6	0.0	0.5	-0.1	-1.3	-2.9	1.1	-0.7	1.2	1.4	0.1
Supplements: Calcium	1.3	1.4	4.3	0.4	2.1	1.8	1.5	0.5	1.7	1.7	-1.3	1.0	0.5	0.9	-0.3	1.1	1.6	0.9	-0.3	0.6	-0.8	-1.0	1.3
Primary Biliary Cirrhosis	1.2	1.7	6.2	-2.0	-0.9	-1.4	0.6	-1.2	1.6	-0.2	0.1	-0.8	0.1	-1.3	0.9	-1.2	0.4	-0.3	2.5	-2.4	1.3	1.3	-2.0
Ever had hysterectomy (womb removed)	1.2	1.3	3.5	0.4	1.0	1.9	1.4	0.6	0.8	1.2	1.8	1.8	1.6	1.0	0.0	0.8	1.2	1.7	-0.7	0.3	-1.2	-1.2	0.2
Average weekly fortified wine intake	1.2	1.4	9.2	-0.3	0.4	1.6	1.1	1.1	1.1	1.0	0.4	1.4	-0.6	1.3	-1.6	1.0	0.6	3.0	-0.6	1.3	-1.4	-0.5	0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.7	8.3	-0.9	1.6	1.7	1.7	1.0	1.7	1.9	2.9	2.0	2.7	1.9	2.4	0.9	1.9	1.6	0.6	-0.3	0.7	-0.0	0.5
Had other major operations	1.2	1.5	3.1	1.8	1.7	1.1	1.2	0.8	1.2	1.7	-0.4	1.4	-0.5	0.8	-1.6	1.1	1.7	1.6	-0.9	0.5	-0.8	-1.3	0.8
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	5.9	-0.3	0.1	2.2	1.2	0.0	0.2	0.6	-1.2	-0.4	1.3	-0.3	-0.9	-0.7	1.1	-0.7	-1.7	-1.4	-1.6	-2.4	-1.5
Falls in the last year	1.2	1.6	5.6	2.0	-0.2	-0.6	0.7	-0.8	0.1	0.3	-2.0	-0.4	-2.4	-0.0	-2.0	0.0	0.6	-1.0	-1.4	-1.5	-1.7	-1.7	-0.8
Happiness	1.2	1.4	6.7	-0.9	1.2	0.6	1.1	0.8	0.7	1.3	0.2	1.6	0.5	1.2	2.6	1.9	1.0	-0.2	1.7	0.4	0.3	1.5	0.9
Mouth/teeth dental problems: Dentures	1.2	2.1	5.4	0.2	-2.0	-2.3	-1.4	-0.8	-0.4	-2.0	-1.3	-1.2	-0.8	-1.9	-0.1	-2.2	-1.4	-1.8	0.0	-2.1	0.1	-0.1	-1.7
Worry too long after embarrassment	1.2	2.0	8.3	1.0	1.1	0.5	-0.5	1.9	-1.1	0.2	0.6	1.0	0.4	2.2	1.0	2.2	-0.9	0.7	0.4	2.9	1.1	1.5	2.9
Age at first live birth	1.2	2.0	7.3	1.2	-1.5	0.9	-0.8	0.3	-0.6	-1.0	-0.8	-0.8	0.7	-1.9	-2.7	-1.7	-0.6	1.0	-2.1	-1.2	-2.0	-2.0	-1.8
Migraine (self-reported)	1.2	1.5	5.0	-0.9	1.6	0.4	-0.0	2.2	-0.7	0.7	1.3	1.6	0.0	1.7	-0.7	2.0	0.0	-0.2	0.1	1.4	1.3	1.0	2.2
Chest pain or discomfort	1.2	1.7	8.0	-0.2	0.2	-2.2	0.2	-0.8	1.0	0.1	-0.3	0.1	-1.1	0.6	2.2	0.8	-0.1	0.2	2.8	0.1	2.0	2.8	0.6
Ever taken oral contraceptive pill	1.2	1.4	4.1	0.3	1.3	-1.3	-0.0	1.1	-1.2	0.6	-0.0	1.3	0.3	0.8	0.7	1.3	0.0	0.8	1.8	1.7	1.4	2.0	1.8
Mother’s age at death	1.2	1.6	6.7	-0.5	-0.8	1.0	1.2	-1.6	0.6	0.2	-0.5	-0.3	-0.0	-1.2	0.3	-1.8	0.7	-0.9	-0.9	-2.2	-1.3	-2.0	-2.6
Eye problems/disorders: Glaucoma	1.2	1.4	5.9	-1.5	-0.7	0.1	0.9	-0.3	1.3	-0.0	0.0	-0.7	1.5	-1.8	-0.2	-1.5	0.9	-0.8	-0.0	-2.2	-0.9	-1.3	-2.4
High cholesterol (Self-reported)	1.2	2.0	15.9	1.4	-0.1	0.6	1.4	-4.0	0.1	1.0	1.3	-0.4	-1.8	-0.1	0.0	-0.7	1.4	0.6	-0.5	-1.5	-1.9	-1.3	-2.0
Medication: Atorvastatin	1.2	1.4	4.9	-0.3	-0.5	-0.6	-0.1	-2.2	0.9	-0.4	-0.4	-1.6	-1.4	-2.2	-1.1	-1.8	0.5	0.3	-0.3	-1.8	-0.7	-0.8	-1.8
Age at First Birth	1.1	1.6	4.8	0.7	-0.4	2.0	-0.1	0.5	0.3	-0.3	-1.4	-1.7	2.1	-1.1	-0.6	-1.7	0.1	0.9	-2.2	-0.7	-1.4	-2.2	0.0
Neuroticism (2016)	1.1	1.7	6.3	-0.5	1.3	-0.1	1.5	-0.9	-1.5	1.3	1.3	1.1	-0.4	2.5	2.1	2.2	0.9	-1.2	0.7	0.3	1.4	0.7	0.8
Allergy or Eczema	1.1	2.8	6.8	1.0	1.2	2.5	1.9	1.2	2.6	2.1	-0.8	0.9	1.6	-0.4	-0.9	0.9	2.3	2.4	-1.7	0.4	-2.6	-2.1	-0.7
Angina	1.1	1.4	4.1	-1.8	-1.4	-1.3	-0.8	-2.0	-0.4	-1.2	0.3	-0.3	-1.6	-1.2	0.1	-1.3	-0.9	-1.0	1.4	-1.1	1.2	1.4	-1.0
Townsend deprivation index at recruitment	1.1	1.6	4.4	-1.3	-0.1	-1.0	1.1	-1.8	0.9	0.2	0.4	1.8	-0.4	-0.4	1.8	-1.0	0.7	-0.7	2.0	-2.1	1.8	0.8	-1.4
Current tobacco smoking	1.1	1.8	5.2	-1.9	-1.3	-1.2	-1.3	-0.7	-0.1	-1.7	-2.3	-1.5	-0.8	-2.2	-0.1	-1.1	-1.5	-2.2	0.3	-0.5	1.4	0.7	-0.5
Taking other prescription medications	1.1	1.7	6.0	1.6	1.4	0.3	1.2	-0.6	0.3	1.5	0.9	2.2	-1.3	2.5	0.2	2.4	1.1	0.9	-0.6	0.8	-0.9	-0.6	1.0
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	6.0	1.1	0.0	-1.7	-0.1	-2.1	-0.1	-0.1	0.2	-0.1	-2.5	0.1	1.5	0.3	-0.3	-1.3	0.9	0.1	1.6	1.4	0.5
High blood pressure (mother)	1.1	1.5	8.0	0.4	-0.6	-1.2	-1.1	-0.3	-1.3	-1.4	-1.8	-2.8	-0.1	-1.2	-2.2	-1.4	-1.2	-0.3	-1.5	-0.3	0.4	-0.9	-0.2
Medication: Cholesterol lowering	1.1	1.8	5.1	1.4	0.5	0.6	1.9	-2.3	0.8	1.1	1.4	-0.9	0.3	-0.8	0.5	-0.4	2.0	1.2	-0.0	-2.0	-2.0	-1.0	-1.9
Length of working week for main job	1.1	1.2	5.1	-0.9	0.7	1.4	-0.5	1.2	-0.9	0.1	0.0	0.6	-0.4	1.7	-0.2	1.3	-0.7	-0.5	-0.4	2.3	1.2	0.6	2.2
Birth weight of first child	1.1	1.9	6.2	2.5	-0.5	0.5	-0.8	-0.5	0.6	-0.7	-1.2	-2.2	0.3	-1.1	-1.3	-2.1	-0.3	2.2	-1.9	-0.3	-1.7	-2.1	-0.5
Ever highly irritable/argumentative for 2 days	1.1	1.3	5.8	0.6	0.2	0.9	1.2	-1.3	0.7	0.6	-1.0	-1.3	1.1	-0.4	-0.4	-1.2	1.3	0.2	-1.1	-1.1	-1.9	-2.4	-1.5
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	7.3	-1.9	-0.2	-1.6	-1.2	2.0	-0.4	-0.6	-1.6	1.1	-0.9	0.4	0.2	0.8	-1.2	-1.8	1.2	1.3	2.7	1.9	1.3
Angina (self-reported)	1.1	1.4	4.7	-1.8	-1.3	-1.4	-0.5	-2.2	0.1	-1.0	0.6	-0.3	-1.4	-1.3	0.3	-1.3	-0.6	-0.8	1.6	-1.3	1.0	1.3	-1.3
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.8	0.1	1.6	1.4	1.7	-1.3	0.8	1.7	0.9	0.3	0.3	1.3	0.7	0.2	1.9	0.8	-1.2	-0.6	-0.7	-1.9	-0.5
Number of self-reported non-cancer illnesses	1.1	1.9	5.5	2.3	1.1	0.4	1.6	-2.2	2.4	1.3	1.6	0.4	-0.7	0.4	0.5	0.6	1.6	1.3	-1.0	-0.8	-1.7	-1.6	-0.4
Number of operations (self-reported)	1.1	1.7	7.9	1.1	1.4	0.5	0.9	1.2	1.0	1.3	0.9	2.8	0.1	1.6	1.2	2.1	0.8	1.5	0.1	1.7	-0.1	0.1	1.4
Age started oral contraceptive pill	1.1	1.4	5.9	-0.4	0.3	-1.1	-0.6	0.8	-0.1	-0.3	1.2	1.5	-0.1	1.3	0.8	1.3	-0.9	0.2	1.4	1.5	2.4	1.8	1.5
Crohns Disease (2017)	1.0	2.2	6.5	-1.7	-1.3	-2.6	-1.4	-0.4	-0.7	-1.6	-0.9	-0.7	-1.6	-1.2	0.8	-0.4	-1.7	-2.1	2.5	0.2	1.7	2.4	0.0
Schizophrenia (2014)	1.0	2.2	7.0	0.8	1.3	1.9	1.3	0.1	0.8	1.5	2.4	0.9	0.9	2.2	0.7	2.3	1.2	2.7	-1.5	2.0	-0.7	-0.8	0.0
Medication for hormone replacement therapy	1.0	1.1	3.8	0.8	0.4	-1.2	1.3	-1.1	0.6	1.1	1.9	1.2	-1.0	1.1	1.6	0.6	1.2	-0.5	1.4	-1.3	0.1	0.4	-0.6
Hayfever, allergic rhinitis or eczema	1.0	2.2	6.5	0.0	1.0	2.1	2.1	0.0	2.4	2.1	0.3	1.1	1.0	-0.1	-0.1	0.4	2.6	2.2	-0.5	-0.9	-2.0	-1.4	-1.4
Chronic bronchitis/emphysema (father)	1.0	1.2	5.3	0.1	0.1	0.2	-1.0	1.2	-1.0	-0.4	0.6	1.1	-0.5	2.1	-1.3	1.4	-1.1	0.5	-0.7	2.3	1.0	0.6	1.4
Illnesses of siblings	1.0	1.4	5.6	1.3	1.0	1.9	0.7	1.3	0.2	0.9	0.4	-0.7	2.1	-0.3	0.1	0.2	1.0	0.8	-2.4	0.3	-1.4	-2.1	0.2
Impedance of arm (right)	1.0	4.8	20.5	2.2	1.7	3.2	0.6	2.0	0.7	1.2	-0.8	0.8	-0.5	2.1	-1.8	3.4	0.0	4.5	-1.3	4.3	-1.0	-0.3	3.2
Number of live births	1.0	1.5	7.2	-0.3	-0.5	-1.9	0.6	-2.1	-0.9	-0.3	-0.9	-0.1	-2.2	-0.4	0.6	-0.1	-0.3	-2.7	1.4	-1.4	1.3	0.7	-0.6
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	3.4	-0.6	1.7	0.8	1.3	0.8	1.4	1.7	-0.3	0.8	1.9	0.5	0.1	0.9	1.7	1.4	0.6	0.4	-0.4	-0.2	0.3
Medication: Seretide 50 evohaler	1.0	1.1	4.8	-1.7	-1.1	-0.9	-0.8	-0.7	-0.4	-1.0	-1.6	0.2	-2.2	-1.0	0.5	-0.1	-1.3	-1.5	0.8	-0.2	0.7	1.1	-0.1
Age at last live birth	1.0	1.5	3.8	1.4	-1.6	-0.0	-0.4	0.1	-0.1	-1.1	-0.8	-0.7	0.5	-1.6	-1.8	-1.6	-0.5	0.0	-1.1	-1.8	-1.8	-1.5	-1.9
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.3	-0.4	-1.2	-0.8	-0.8	-1.8	-0.3	-1.0	-1.7	-1.3	-1.3	-1.5	-1.1	-1.5	-0.6	-0.8	-0.5	-1.0	-0.5	-0.6	-1.0
Knee pain experienced in last month	1.0	1.6	8.6	0.7	-1.2	-1.4	-1.7	-0.4	-1.1	-1.2	-2.1	-0.2	-2.9	-0.2	-2.5	0.0	-1.4	-0.3	-0.6	0.1	-0.2	0.5	0.1
Mood swings	1.0	1.8	5.5	0.6	1.6	0.3	2.0	-0.8	0.3	1.8	1.7	2.0	-0.5	1.9	1.7	2.3	1.7	-0.5	1.2	0.7	0.0	0.8	0.8
Medication: Gliclazide	1.0	1.1	6.2	2.0	1.2	-1.2	1.0	0.9	-0.0	0.9	-1.0	0.2	2.5	-0.4	1.3	-0.4	1.3	0.5	0.9	-0.8	0.4	-0.2	0.0
Average weekly beer plus cider intake	1.0	1.5	7.4	-0.8	-1.6	0.1	-1.1	-0.3	-0.8	-1.2	-2.7	-1.8	0.5	-1.5	-1.1	-1.9	-0.8	0.4	-0.2	-1.2	-1.1	-0.4	-1.2
Schizophrenia (2018)	0.9	1.9	4.8	1.1	2.2	1.4	1.9	-0.6	1.3	2.0	1.8	0.3	0.6	1.8	1.2	2.1	1.7	1.7	-0.3	1.4	-0.2	-0.4	0.0
Ovarian Cancer	0.9	1.2	3.2	-1.7	-1.4	0.1	-1.8	1.3	-1.7	-1.3	-1.8	0.5	-0.6	-0.0	-1.2	-0.0	-1.7	-1.0	-0.5	0.8	0.2	0.6	0.2
Average weekly spirits intake	0.9	1.1	3.8	-0.1	-2.0	-1.5	-0.5	-0.4	-0.5	-1.2	0.8	-0.4	-0.8	-1.1	0.3	-1.1	-0.9	-0.6	1.1	-1.4	-0.3	1.0	-1.9
Impedance of leg (right)	0.9	4.3	12.7	3.6	1.3	2.3	1.6	0.8	2.2	1.9	-1.2	-0.6	0.7	0.8	-2.7	1.6	1.6	2.7	-2.6	1.8	-3.5	-3.1	0.9
Qualifications: CSEs or equivalent	0.9	1.2	5.4	0.3	-1.4	-1.5	-2.3	-0.3	0.0	-1.8	-1.3	-1.3	-1.0	-0.9	-0.8	-0.5	-1.8	-0.9	-0.2	0.5	-0.3	0.9	0.3
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	6.4	0.8	-0.1	0.1	-1.0	-1.3	1.4	-0.3	0.4	-0.1	-2.5	1.1	-2.2	0.7	-0.4	1.1	-0.1	0.7	-0.6	0.3	1.1
Past tobacco smoking	0.9	1.7	6.7	-0.9	-1.1	-0.6	-2.3	0.4	-0.7	-2.1	-0.3	-2.0	-0.6	-0.0	-1.2	-0.6	-2.6	-0.2	0.1	0.8	2.1	1.5	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	5.9	-1.3	1.5	1.1	1.5	0.7	1.6	1.8	2.4	1.8	2.0	1.7	2.1	0.8	1.9	1.2	1.1	-0.6	0.5	0.4	0.3
Gout (self-reported)	0.9	1.2	4.2	-0.3	1.0	-0.1	2.0	-1.3	1.6	1.6	0.3	-0.1	0.3	0.2	0.3	0.5	2.1	0.9	1.9	-1.3	-0.7	0.2	-0.7
Eye problems/disorders: None of the above	0.9	1.1	5.1	0.4	1.3	0.6	0.1	0.3	-1.0	0.5	-0.1	0.9	-1.0	2.0	0.1	1.6	-0.3	0.7	0.2	1.8	0.7	0.6	2.3
Medication: Omeprazole	0.9	1.1	5.5	-1.1	-0.6	-1.7	-1.0	-1.1	-0.0	-0.9	0.3	-0.1	-1.4	0.8	1.0	0.0	-1.0	-2.3	1.3	-0.6	1.1	1.2	0.2
Mean time to correctly identify matches	0.9	1.7	6.4	0.2	-1.9	-1.2	-2.2	0.1	-1.8	-2.5	-0.2	-1.5	-0.0	-1.2	-0.7	-1.6	-2.4	-0.4	-1.1	-0.4	0.0	-0.2	-0.7
Alcohol intake frequency.	0.9	2.2	7.4	-1.8	-1.6	-1.9	-0.6	0.5	-1.6	-1.6	-2.3	-0.1	-0.7	-0.9	-1.2	-1.1	-1.1	-2.7	-0.4	-2.6	0.2	-0.7	-1.9
Eye problems/disorders: Cataract	0.9	1.0	3.6	-1.0	-1.6	-1.1	-0.6	-0.9	-0.2	-0.7	-1.0	-0.9	-0.5	-1.9	-0.2	-1.5	-0.2	-0.4	0.6	-1.5	0.3	0.4	-1.8
Back pain experienced in last month	0.9	1.3	5.5	1.6	1.2	1.1	0.6	0.3	-1.1	1.0	2.0	1.5	-0.9	2.3	-0.9	1.4	0.5	0.9	-0.8	1.0	-0.2	-0.4	1.1
Pain type(s) experienced in last month: Hip pain	0.9	1.1	3.7	-0.0	-1.3	1.3	-0.8	-0.9	0.3	-0.8	-1.7	0.5	-0.8	0.4	-1.4	-0.8	-0.8	0.6	-1.9	0.3	-1.5	-1.6	-0.6
Commuting to job workplace: Cycle	0.9	1.1	5.6	0.2	-0.6	-1.4	-0.5	-2.4	1.0	-0.4	0.9	-0.0	-2.1	-0.1	0.2	-0.2	-0.4	0.0	1.8	-0.2	0.7	1.7	-0.0
Cholesterol lowering medication	0.9	1.3	11.6	-0.6	-1.3	0.2	-0.3	-3.4	-0.3	-0.6	0.3	0.5	-2.3	-0.3	-0.6	-1.2	-0.5	-0.9	-0.0	-0.8	-0.5	-0.3	-1.3
Neuroticism (Nagel 2018)	0.8	1.9	7.8	-1.1	1.3	0.8	1.4	-0.0	-1.2	1.4	1.2	2.2	-0.8	2.8	1.6	2.4	1.1	-0.8	0.9	0.8	1.1	1.0	0.8
Hearing difficulty/problems: Yes	0.8	1.2	3.6	1.2	-1.9	-1.0	-1.8	0.7	-0.2	-1.4	-1.0	0.0	-0.6	-0.5	-1.3	-0.4	-1.8	0.0	-1.2	0.8	-1.6	-0.3	-0.6
Hand grip strength (right)	0.8	2.2	7.0	-2.6	-0.7	0.0	-0.6	-1.2	-0.4	-0.7	2.0	0.6	-1.1	-0.3	2.2	-0.5	-1.0	-2.4	1.9	-0.6	2.5	2.4	0.2
Impedance of leg (left)	0.8	3.7	9.0	3.0	1.6	2.0	1.8	1.1	2.1	2.1	-0.9	-0.2	0.3	1.1	-2.8	2.1	1.7	2.1	-2.0	1.8	-2.9	-2.4	1.1
Medication: Simvastatin	0.8	1.2	7.6	2.0	-0.2	1.1	1.0	-2.8	0.7	0.6	0.8	0.1	-1.1	-0.2	-0.5	-0.4	0.6	0.4	-0.6	-0.4	-2.1	-1.1	-0.8
Hip circumference	0.8	3.3	8.4	0.6	2.1	1.0	1.6	2.7	1.4	1.8	2.9	2.3	2.4	1.5	1.6	2.0	1.5	2.9	1.8	0.9	0.5	1.2	1.0
Depression (self-reported)	0.8	1.0	3.8	-0.4	0.8	0.9	1.9	-0.4	1.5	1.4	0.7	1.3	-0.3	0.5	0.4	0.7	1.7	1.1	-0.3	-0.8	-0.7	-0.9	-0.9
Standing height	0.8	7.7	31.1	0.2	2.5	3.7	0.4	5.6	-1.7	1.4	3.2	1.8	4.3	3.1	0.6	2.7	0.1	4.5	-1.5	3.7	0.1	0.2	3.5
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	5.0	1.0	1.0	1.2	-0.1	2.0	0.1	0.3	1.0	-0.3	2.2	-0.0	-1.2	-0.3	0.1	2.2	-1.2	1.0	-0.1	-0.7	1.2
Financial situation satisfaction	0.8	1.0	2.9	0.2	1.7	0.8	1.5	0.5	0.6	1.5	1.5	1.2	0.4	0.8	1.2	1.2	1.4	0.3	0.8	-0.1	-0.5	0.4	1.0
Supplements: Fish oil (including cod liver oil)	0.8	1.1	3.6	1.5	1.5	0.6	0.5	0.5	0.3	1.2	1.4	0.2	0.9	1.2	0.1	1.2	1.1	1.9	-0.8	1.3	-0.1	-0.7	1.4
Depressed Affect (Nagel 2018)	0.7	1.6	3.9	-1.1	0.5	-1.1	0.7	0.1	-1.3	0.6	0.2	2.0	-1.3	1.6	1.4	1.8	0.4	-1.9	1.8	0.3	1.6	1.8	0.5
Reaction Time	0.7	1.4	3.7	1.6	-0.9	-0.5	-1.7	1.2	-1.8	-1.7	-0.6	-1.3	0.1	-0.4	-1.5	-0.4	-1.9	0.5	-1.9	0.5	-0.4	-0.6	0.5
Height	0.7	12.9	43.6	0.9	4.0	4.7	0.5	6.6	-1.9	2.4	3.4	1.4	4.9	4.2	0.6	4.3	1.0	6.2	-1.9	5.2	0.4	0.5	4.7
Waist Hip Ratio (WHR)	0.7	3.2	6.8	-1.6	-2.4	-1.3	-0.8	-0.8	-2.5	-1.5	-2.1	0.4	-2.0	-0.6	-2.2	-0.7	-1.2	-2.6	-1.9	-2.1	-2.3	-1.9	-2.1
Relative age voice broke	0.7	1.0	5.7	0.3	1.2	1.1	0.4	-0.1	-0.7	0.7	1.4	0.1	0.6	0.6	0.6	1.0	0.3	2.4	0.3	2.0	0.2	0.5	1.5
Multivitamins +/- minerals	0.7	0.9	3.7	0.8	0.1	-0.0	0.3	0.1	0.3	0.3	-1.3	-0.1	-0.0	-0.2	-1.5	-0.7	0.8	-0.7	-1.4	-1.9	-1.1	-1.9	-0.7
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.2	-0.5	-0.1	1.0	1.0	1.5	1.4	0.6	1.0	0.9	1.3	-0.8	-0.2	-0.5	0.9	1.5	0.0	-1.0	-1.1	-0.7	-1.2
Fluid intelligence score	0.7	1.4	10.5	0.5	0.9	1.1	-0.1	0.9	0.7	0.5	0.2	-0.5	1.4	-0.2	-2.2	0.1	0.4	3.2	-0.2	2.1	0.0	0.1	1.1
Time employed in main current job	0.7	0.8	4.1	0.2	0.2	0.6	1.4	-1.3	1.2	0.8	1.1	-0.0	0.1	0.2	-0.2	0.4	1.1	2.0	0.3	-0.3	-0.7	-0.3	-1.1
Father’s age at death	0.7	0.9	2.9	0.8	1.3	0.6	1.5	0.3	-0.6	1.6	-0.9	1.7	0.5	1.4	0.3	1.1	1.3	-0.3	-0.4	0.4	-0.7	-0.8	0.3
Medication: Lansoprazole	0.7	0.8	2.9	-1.6	-0.1	-1.3	-0.6	-0.7	1.7	-0.2	0.4	-1.1	-0.6	-0.5	0.4	-0.1	0.1	-0.2	1.3	-0.3	0.9	1.5	0.0
Impedance of arm (left)	0.7	3.2	13.8	1.5	1.0	2.7	0.0	1.5	0.4	0.7	-0.7	0.9	-0.9	1.8	-1.4	3.0	-0.4	3.4	-0.6	3.7	-0.6	0.3	2.9
Pulse wave reflection index	0.7	0.8	2.5	-1.0	-1.5	-0.4	-0.6	-0.7	-0.6	-1.2	-0.4	-0.5	-1.6	-1.1	-1.3	-0.9	-1.1	-0.4	0.2	-1.1	-0.1	0.0	-1.3
Medication: Paracetamol	0.7	1.2	4.5	-0.5	-0.7	-0.8	-1.5	1.0	-1.2	-1.1	-2.1	0.8	-1.6	-0.5	-1.0	0.4	-1.5	-1.2	0.5	0.7	0.8	1.5	0.5
Birth weight	0.7	1.5	4.6	1.7	0.9	1.6	0.1	1.5	-0.9	0.4	-1.1	1.1	1.0	1.4	-0.5	0.6	-0.0	2.1	-1.7	1.5	-1.2	-1.2	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	3.3	-0.2	1.8	0.8	1.2	0.5	0.8	1.4	0.5	0.7	0.8	0.6	1.3	1.3	1.2	0.6	0.4	0.7	1.1	0.5	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	4.2	-2.0	-0.5	-0.5	0.2	0.1	0.4	-0.4	0.6	0.9	-0.3	-1.0	0.7	-0.0	-0.2	-1.6	1.4	-1.2	0.5	0.9	-0.7
Illnesses of siblings: Diabetes	0.7	0.9	4.3	-0.1	-0.2	-1.5	1.1	-1.0	0.6	0.5	-0.7	0.2	0.0	-0.4	-0.2	0.1	0.9	-0.6	2.1	-1.8	-0.0	1.1	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.0	-0.3	0.4	0.8	1.3	-1.4	0.4	0.6	1.2	0.4	0.5	-1.0	1.2	-0.0	1.0	-0.6	0.4	-1.3	-0.7	-0.2	-1.1
Osteoarthritis (self-reported)	0.7	0.9	7.0	-0.9	-1.2	-0.5	-1.2	-0.1	-0.7	-0.8	-0.5	2.7	-1.9	0.2	-0.7	0.3	-1.0	-0.1	0.1	0.4	0.0	0.7	0.1
Medication: Bendroflumethiazide	0.7	1.1	5.6	-1.7	0.7	2.4	0.4	-0.4	-1.8	0.9	-0.7	0.8	-0.3	0.9	0.7	1.4	0.6	-1.4	-0.4	0.1	0.6	0.2	0.5
Medication: Paracetamol	0.7	1.1	3.3	-0.2	-1.0	-0.6	-1.7	1.2	-1.8	-1.4	-1.6	0.9	-1.0	-0.5	-0.8	-0.0	-1.7	-1.2	-0.4	0.6	0.5	0.7	0.2
Ever smoked	0.7	1.1	3.8	0.7	-0.2	-0.1	1.3	-1.8	0.6	0.8	-0.5	0.3	-0.6	-1.0	0.5	-1.0	1.4	-0.4	-0.1	-1.3	-1.9	-1.5	-1.9
Fractured/broken bones in last 5 years	0.7	1.0	5.6	0.8	-0.6	1.1	0.5	-0.1	0.4	-0.2	-0.9	0.1	-0.1	-0.8	-0.3	-0.5	0.2	-0.1	-1.2	-1.4	-2.4	-1.8	-1.5
Diastolic blood pressure, automated reading	0.7	2.1	6.4	1.4	1.5	2.3	1.1	-0.3	1.4	1.5	1.5	0.9	0.0	2.1	1.3	2.0	0.7	1.1	-0.6	2.5	-1.2	-0.5	2.1
Heart disease (siblings)	0.7	0.9	2.4	-0.5	-0.9	-1.0	-1.6	-1.3	-1.0	-1.3	-1.0	-0.5	-1.4	-0.2	-0.8	-0.6	-1.4	-0.8	0.4	0.9	0.8	0.9	0.5
Impedance of whole body	0.7	3.8	10.6	2.8	1.5	2.6	1.1	1.5	1.2	1.6	-0.8	0.3	-0.4	1.8	-2.1	3.1	0.7	3.1	-1.5	3.3	-1.9	-1.1	2.4
Verbal and Numeric Reasoning (VNR)	0.6	1.5	5.2	1.6	0.2	0.5	-0.7	1.0	-0.3	-0.1	-1.6	-1.2	0.9	-0.9	-2.3	-0.4	-0.1	2.1	-1.8	1.9	-1.3	-1.1	0.5
Lupus	0.6	0.9	4.0	-0.7	-0.5	-0.6	0.4	-1.4	0.9	-0.2	0.8	0.0	-0.2	-0.3	2.0	-0.5	0.1	-2.0	0.7	-1.8	-0.7	-0.1	-0.9
Number of treatments/medications taken	0.6	1.1	3.7	0.3	0.7	-0.5	0.6	-1.6	-0.5	0.7	1.6	1.9	-1.4	1.3	1.6	1.4	0.5	-0.4	0.9	0.1	0.6	0.9	0.4
Relative age of first facial hair	0.6	1.2	5.7	0.6	0.2	2.1	-0.1	0.2	-1.2	0.1	0.6	-0.5	1.5	0.4	-0.9	0.0	-0.2	2.4	-1.4	1.9	-1.2	-1.0	0.7
Systolic blood pressure, automated reading	0.6	1.8	5.9	-0.3	-1.8	-1.8	-1.8	-1.2	-1.6	-1.7	-1.4	-1.5	-1.3	-0.8	0.9	-1.1	-2.0	-2.4	0.3	0.7	0.3	0.8	0.2
Qualifications: None of the above	0.6	1.2	4.8	-0.7	-1.4	-0.8	-0.2	-2.1	-1.5	-0.9	-0.5	0.1	-1.2	-0.1	1.0	-0.5	-0.7	-2.2	0.1	-1.5	-0.8	-0.2	-1.6
Heart attack	0.6	0.7	2.0	0.4	-0.9	-0.5	-0.7	-1.1	-1.4	-1.2	-0.5	-1.0	-0.5	-1.2	-1.4	-0.9	-1.0	-0.5	-0.5	-0.6	-0.4	-0.1	-0.5
Allergy	0.6	1.3	4.4	-0.4	-0.9	-1.6	-1.6	-0.2	-1.5	-1.9	-0.6	-1.7	-0.4	-0.4	-0.6	-0.5	-2.1	-1.8	0.3	0.5	1.0	0.8	0.7
Neuroticism score	0.6	1.2	4.2	0.2	1.4	0.4	1.1	-0.2	-0.5	1.1	0.7	1.2	-0.2	1.6	1.6	2.1	0.7	-0.7	0.9	1.0	1.1	1.0	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	6.3	-0.4	-0.7	-1.3	-1.1	-0.3	-1.4	-1.1	-1.0	-0.7	-0.8	0.1	0.3	-0.2	-1.2	-2.5	0.1	0.1	1.4	0.9	0.3
Breastfed as a baby	0.6	0.8	1.5	-0.8	-1.2	1.0	-1.0	1.0	-0.9	-0.9	-0.7	-0.3	0.7	-0.4	-0.7	-1.1	-1.0	0.9	-1.2	0.2	-1.2	-0.7	-0.7
High blood pressure (siblings)	0.6	0.8	5.0	-1.2	-0.1	-0.7	0.0	-1.0	0.9	0.0	0.8	0.7	-1.2	0.6	0.5	0.1	0.1	0.1	2.2	-0.5	1.0	1.8	-0.1
Medication: Blood pressure	0.6	1.1	4.3	1.6	-0.4	0.8	0.2	-1.7	0.2	-0.3	0.5	-1.3	0.8	-1.1	-0.5	-1.2	0.1	0.6	-1.1	-0.8	-2.1	-1.4	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.2	1.1	-0.7	-0.0	0.1	0.6	-0.5	-0.3	-1.2	-1.3	0.6	-0.7	-0.4	-1.4	-0.0	0.7	-0.8	-0.2	-1.0	-1.5	-0.8
Medication: Aspirin	0.6	0.7	4.6	-0.7	-0.2	-1.4	0.2	-0.7	0.5	-0.3	1.2	0.5	0.3	-0.5	0.6	-0.3	0.1	0.5	2.1	-0.7	0.7	1.5	-0.6
Medication: Lisinopril	0.6	0.7	3.1	-0.1	0.5	-0.5	0.6	-1.8	1.4	0.3	0.5	-1.2	0.2	-0.2	1.3	-0.1	0.4	-0.5	1.5	-0.4	1.1	1.2	-0.1
Ever had prostate specific antigen (PSA) test	0.6	0.7	4.0	0.6	-0.4	1.7	-0.1	0.2	0.5	-0.0	1.5	0.4	0.1	0.4	-0.6	0.2	-0.2	0.3	-2.0	0.8	-1.3	-1.3	0.2
Pack years of smoking	0.6	0.9	3.9	1.1	-0.0	-1.3	0.6	-2.0	1.3	0.4	1.1	-0.7	-0.6	-0.6	0.9	0.2	0.8	-0.8	0.5	-1.7	-0.2	0.3	-1.1
Schizophrenia vs Biploar Disorder	0.5	0.6	2.5	0.0	1.1	1.1	1.0	0.0	1.6	1.1	0.3	0.2	1.0	0.2	-0.0	0.8	1.1	0.9	0.0	1.2	0.0	0.0	0.0
Alzheimer’s Disease (in father)	0.5	0.5	2.2	0.7	0.3	0.3	0.8	0.6	1.0	0.7	-0.3	1.4	-0.9	0.8	-0.5	1.5	0.3	0.7	0.5	0.4	-0.2	0.5	0.4
Prostate Cancer	0.5	0.8	4.9	-1.2	-0.0	2.2	-0.8	-0.3	-0.4	-0.1	0.7	-0.1	0.2	0.5	-0.8	-0.5	-0.2	1.8	-1.2	1.0	-0.2	-0.5	0.4
LDL Cholesterol	0.5	0.8	3.5	-1.5	0.6	-0.6	1.0	-0.8	1.7	1.0	0.0	0.6	0.2	-0.5	1.1	0.2	1.2	0.3	1.9	-0.5	0.0	0.0	0.0
Triglycerides	0.5	0.8	4.3	0.3	1.0	0.0	1.5	-0.2	2.1	1.3	-0.2	-0.9	1.4	-0.7	-0.1	0.4	1.6	1.0	0.4	-0.4	0.0	0.0	0.0
Lung FVC	0.5	2.5	12.1	0.7	2.0	3.5	1.6	0.9	1.5	2.1	1.0	1.9	1.3	1.7	-0.1	1.8	1.7	2.0	-0.2	1.6	-0.7	-0.3	1.4
Hand grip strength (left)	0.5	1.3	8.3	-2.0	0.1	0.2	-0.0	-0.8	0.2	-0.1	1.3	-0.1	-0.0	-0.6	2.9	-0.3	-0.2	-1.5	1.4	-0.5	1.7	1.7	0.3
Ever used hormone-replacement therapy (HRT)	0.5	0.6	3.8	1.9	-0.0	-1.0	0.1	0.5	0.2	-0.1	1.3	0.1	-0.3	0.9	0.0	1.0	-0.4	0.5	-0.8	1.3	-0.5	-0.6	0.7
Pack years adult smoking proportion	0.5	0.8	2.9	0.7	-0.1	-1.5	0.5	-1.4	1.2	0.3	1.0	-0.5	-0.4	-0.6	1.0	0.4	0.6	-1.1	0.7	-1.7	0.1	0.6	-1.1
Maternal smoking around birth	0.5	0.7	2.4	0.3	0.6	-0.5	0.0	1.0	-0.8	0.4	-0.4	-0.0	0.4	0.6	1.0	1.6	0.0	-1.4	0.6	1.0	0.5	1.1	1.3
Age when periods started (menarche)	0.5	1.1	3.6	-1.3	0.1	1.3	1.0	-0.7	1.1	0.2	0.7	-1.9	1.3	-1.4	-0.3	-0.9	0.9	-0.0	-0.5	-1.7	-0.3	-1.2	-1.4
Stomach or abdominal pain in last month	0.5	0.7	2.0	0.5	-0.1	-0.7	0.5	-1.4	0.8	-0.1	0.7	-0.9	-1.2	-0.6	-1.4	-0.2	0.3	0.5	-0.7	-1.2	-0.7	-0.9	-1.1
Supplements: Glucosamine	0.5	0.7	3.3	-0.6	-0.2	0.8	-0.9	0.8	-0.9	-0.4	-1.8	1.4	-0.3	0.5	-1.4	-0.0	-0.8	-0.4	0.0	1.0	-0.5	0.1	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	4.4	-1.2	0.7	0.3	0.9	0.1	0.3	0.6	2.1	0.7	0.3	1.4	1.8	1.1	0.6	-0.4	0.7	-0.2	0.6	0.6	0.0
Noisy workplace	0.5	0.6	4.2	-0.4	-0.4	-1.9	-0.7	-0.1	-0.4	-0.4	0.3	0.3	-1.3	-0.2	0.1	0.2	-0.4	-2.1	-0.1	-0.5	0.3	0.3	-0.0
Prospective memory result	0.5	0.6	2.6	-0.6	-0.6	-0.2	-1.6	0.2	-1.0	-1.3	-0.9	-0.9	-0.5	-0.7	-1.0	-0.7	-1.1	-0.7	-0.8	-0.2	0.0	-0.2	0.3
Illnesses of mother	0.5	0.6	3.4	-1.8	-0.7	1.0	-1.2	1.0	0.3	-0.7	-0.5	0.4	0.6	-0.0	0.4	-0.2	-0.8	-0.4	0.7	-0.0	-0.2	0.9	0.3
Tense / ‘highly strung’	0.5	0.8	2.5	-0.7	1.1	1.5	1.2	-1.2	0.2	1.3	1.5	0.4	-0.2	1.6	0.8	1.1	1.2	0.2	0.0	0.4	0.0	-0.1	0.0
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.5	-1.1	-0.2	1.2	0.2	1.4	-1.4	-0.3	-1.6	0.8	0.5	-0.2	1.2	0.7	-0.7	-0.5	-0.1	0.6	-0.7	-0.0	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.0	-0.1	0.3	1.4	1.2	-0.1	0.8	0.9	-0.5	0.3	0.7	0.4	0.8	-0.5	0.9	1.1	0.5	-0.4	-1.4	-0.7	-0.7
Neck or shoulder pain in last month	0.5	0.7	2.6	1.2	-0.2	-1.5	-0.6	-1.4	-0.6	-0.3	0.6	0.8	-1.4	0.8	0.6	0.2	-0.5	-1.6	0.1	0.3	0.5	0.4	0.3
Had major operations	0.5	0.6	3.2	-0.2	-0.2	-0.0	-0.2	1.0	0.7	-0.6	1.2	0.5	1.6	-0.9	1.8	-0.5	-0.5	0.8	0.5	-0.0	-0.9	0.1	-0.0
Medication: Aspirin	0.5	0.7	4.3	-0.6	-0.1	-1.1	0.6	-1.2	0.6	0.0	1.0	0.6	-0.4	-0.4	0.4	-0.1	0.4	0.3	2.1	-1.1	0.4	1.3	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	1.5	-1.2	0.5	-0.2	-0.8	-1.0	0.9	-0.2	-0.4	-0.8	-0.4	-0.1	0.8	-0.0	-0.3	-0.6	0.9	0.6	0.9	1.2	1.0
Illnesses of father: Heart disease	0.5	0.7	2.0	-0.3	-0.8	-0.9	-0.2	-0.5	0.7	-0.7	0.8	-1.4	0.4	-1.0	-0.5	-0.9	-0.1	-0.6	-1.2	-1.3	-0.4	-1.4	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	4.7	0.8	0.9	2.2	1.1	1.4	-0.1	1.4	0.7	0.9	1.1	0.7	-0.1	0.7	1.0	1.6	-1.0	0.9	-1.2	-0.8	0.4
Loneliness, isolation	0.5	0.7	2.4	-0.3	-0.4	-1.4	-0.3	-0.9	-1.3	-0.1	-1.1	-0.4	-0.6	-0.1	1.5	0.4	0.0	-1.0	1.0	-0.3	0.7	1.4	-0.4
Medication for cholesterol	0.5	0.7	4.2	0.2	0.3	0.7	-0.8	2.1	0.1	-0.6	-0.6	-0.9	1.5	-0.6	-0.1	-0.0	-0.8	1.0	-0.7	1.2	0.3	0.0	1.2
Illnesses of father: None of the above (group 1)	0.5	0.7	2.3	-0.7	-0.0	0.1	-0.3	1.2	-1.3	-0.4	-0.3	0.8	0.9	-0.1	1.2	-0.6	-0.5	0.0	1.5	0.1	1.1	1.4	0.4
Miserableness	0.5	0.9	3.2	-0.4	1.2	0.5	1.4	-1.0	0.2	1.1	0.3	1.0	0.1	0.9	1.8	1.3	1.2	-1.2	1.2	-0.1	0.0	0.4	0.1
Guilty feelings	0.5	0.7	2.7	0.3	0.9	0.8	0.9	1.6	-0.7	0.8	-1.4	0.6	0.2	0.8	-0.6	1.3	0.5	0.1	-1.0	0.7	-0.1	-0.5	0.7
Commuting to job workplace: Public transport	0.5	0.6	2.3	1.5	0.6	-0.2	0.6	0.3	0.6	0.6	1.1	0.0	0.2	1.2	0.0	1.3	0.2	1.1	0.5	1.3	-0.2	0.5	0.7
Ever depressed for a whole week	0.5	0.6	2.3	-0.1	0.5	1.5	0.7	-0.3	0.5	0.8	-0.3	-0.3	1.1	-0.2	0.0	-0.7	1.3	-0.2	-0.5	-0.7	-1.1	-1.4	-0.9
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.0	0.7	-0.7	-0.3	-0.7	-1.0	-1.4	-1.1	-0.1	-1.0	-0.4	-1.1	-1.4	-0.8	-1.0	-0.1	-0.5	-0.6	-0.5	-0.1	-0.3
Bipolar Disorder (2018)	0.4	0.6	1.8	-1.3	-1.2	-0.5	-0.9	0.2	-1.0	-0.9	0.9	0.3	-0.5	0.2	1.4	0.3	-1.1	-0.2	0.7	0.1	0.5	1.2	0.0
Bipolar Disorder or Schizophrenia	0.4	1.0	4.1	-0.0	1.0	0.7	0.9	-0.3	0.2	0.9	2.0	0.3	0.1	1.5	1.8	1.9	0.6	1.2	0.2	1.1	0.2	0.4	0.0
Worry (Nagel 2018)	0.4	0.9	4.1	-0.0	0.9	1.5	1.0	-0.8	-0.6	0.8	1.9	0.5	-0.4	2.0	0.7	1.2	0.5	0.1	-0.6	0.6	0.2	-0.3	0.6
Major Depression (MDD)	0.4	0.5	2.6	0.5	0.7	1.0	1.1	-0.6	0.7	1.0	0.0	0.0	0.5	0.8	-0.1	0.7	1.1	1.6	0.0	-0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.4	0.5	2.5	0.0	-0.6	-1.0	0.2	-0.7	0.4	-0.5	1.4	0.4	0.3	-0.2	1.6	-0.6	-0.4	-0.2	0.0	-1.3	0.0	0.0	0.0
HDL Cholesterol	0.4	0.6	2.5	-0.2	-0.9	0.5	-1.5	0.9	-1.6	-1.2	-0.8	0.1	0.1	0.0	0.2	-0.8	-1.5	-0.4	-0.3	0.7	0.0	0.0	0.0
Blood Eosinophil Count	0.4	3.1	8.1	2.4	1.4	0.1	-0.2	2.9	-1.8	0.6	-2.8	1.7	0.8	1.7	-2.0	2.1	0.0	2.4	-1.4	2.2	-0.1	0.1	2.4
Heel T-Score	0.4	3.0	15.8	0.6	1.4	-0.6	1.0	-0.2	0.4	1.1	4.0	1.0	1.1	2.0	3.5	1.1	0.9	0.1	2.4	-0.1	2.7	2.0	1.3
Systolic Blood Pressure	0.4	2.0	9.3	0.5	-0.7	-0.8	-1.5	-0.5	-2.1	-1.0	-1.5	-1.0	-1.6	0.6	1.7	0.7	-1.8	-3.0	0.1	1.5	0.5	1.2	1.9
Smoking Status	0.4	0.9	4.8	-0.6	-0.0	-0.9	0.2	-1.2	1.3	-0.0	-2.2	-0.0	-0.9	-1.7	0.3	-0.1	0.4	-2.1	0.0	-0.5	-0.0	-0.4	-0.6
Respiratory disease	0.4	0.8	5.1	1.7	-0.7	0.0	-0.5	1.0	0.1	-0.7	-0.9	-0.3	0.1	-0.8	-0.7	-0.6	-0.6	-0.1	-2.3	-0.2	-0.8	-1.7	-0.4
Lung FEV1/FVC ratio	0.4	2.0	8.4	0.0	-0.9	-2.2	0.6	-2.2	0.3	-0.3	0.0	-2.9	-0.7	-1.4	-1.0	-2.1	0.5	-0.4	1.4	-2.3	0.7	0.1	-2.1
Vitamin and mineral supplements	0.4	0.6	3.6	0.3	-0.2	-0.1	-0.0	-0.3	-0.7	-0.1	1.0	0.0	0.8	0.2	1.9	0.5	-0.5	0.2	0.9	1.5	0.8	1.2	0.3
Trunk fat percentage	0.4	1.6	6.5	0.4	1.2	0.4	1.6	1.3	1.1	1.5	1.1	2.6	0.8	1.0	0.8	2.0	1.5	1.6	1.5	0.1	-0.4	0.7	0.1
Fed-up feelings	0.4	0.8	3.3	0.5	0.9	-0.8	1.0	0.1	-0.7	1.0	-0.5	1.8	-0.3	1.0	1.0	1.2	0.9	-1.4	0.9	0.3	0.3	0.6	0.4
Serious illness, injury or assault to yourself	0.4	0.5	1.9	1.3	-0.4	-0.4	0.1	-0.9	0.8	-0.2	0.9	1.0	-1.4	-0.2	0.4	0.2	-0.4	0.7	-0.4	0.3	-1.1	-0.6	-0.3
Sitting height	0.4	2.8	18.7	-0.7	0.3	2.2	-0.4	4.3	-3.0	-0.1	-0.6	-0.7	3.0	0.9	-1.5	0.1	-0.6	1.2	-2.4	0.7	-0.3	-1.1	0.7
Leg predicted mass (left)	0.4	1.9	7.9	-1.9	0.3	0.2	-0.7	2.8	-1.4	-0.4	2.1	1.5	2.4	0.5	1.7	0.1	-0.6	0.8	1.1	0.0	1.5	1.8	0.5
Trunk fat mass	0.4	1.8	7.4	-0.1	1.2	0.5	1.3	1.8	0.6	1.4	1.8	2.7	1.5	1.3	1.2	1.8	1.3	1.6	1.5	0.1	-0.1	1.0	0.2
Hair/balding pattern: Pattern 2	0.4	0.5	2.6	0.3	0.0	0.7	0.5	0.2	0.6	0.4	0.3	1.0	-1.6	1.6	-0.5	0.9	0.0	0.8	-0.1	0.8	-0.8	-0.1	0.0
Forced vital capacity (FVC)	0.4	1.7	10.7	0.0	0.8	3.3	-0.1	2.6	-1.0	0.4	-0.2	-0.0	1.5	1.1	-0.1	1.2	-0.3	1.4	-0.6	2.1	0.3	0.6	1.7
Financial difficulties in last 2 years	0.4	0.6	3.6	-0.2	-0.3	-1.1	-0.1	-0.5	-0.2	-0.4	-1.9	-0.5	-0.3	-0.9	0.5	-0.9	-0.1	-0.7	0.6	-1.5	0.8	0.3	-0.6
Weight	0.4	1.9	6.0	-0.9	1.1	0.4	0.8	2.4	0.0	0.9	2.4	2.4	2.5	1.1	1.7	1.0	0.8	1.5	1.5	-0.1	0.7	1.2	0.3
Asthma	0.4	0.7	2.5	1.6	0.9	1.0	0.9	0.7	0.1	1.1	-0.5	0.9	-0.2	0.6	0.4	1.1	0.7	0.7	-1.3	0.7	-0.1	-1.0	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.2	0.0	-0.5	-1.2	-0.9	0.5	-0.5	-0.7	-0.5	0.0	-1.5	0.2	-0.5	0.5	-1.0	-0.5	0.4	0.6	0.2	1.0	0.6
Pulse wave Arterial Stiffness index	0.4	0.4	1.9	0.0	-0.1	-0.8	-1.0	1.1	-0.4	-0.7	0.3	0.7	-0.5	-0.7	-1.4	-0.0	-0.9	-0.2	0.2	-0.0	0.8	0.4	0.7
Trunk predicted mass	0.4	2.0	11.7	-1.3	0.9	0.7	-0.2	3.1	-1.3	0.1	2.5	1.3	3.4	1.0	1.8	-0.0	-0.0	0.6	0.1	0.0	0.7	0.7	0.6
Hair/balding pattern: Pattern 4	0.4	0.9	3.3	-0.8	-0.2	-0.3	-0.9	-1.1	-1.5	-0.2	-0.7	0.4	-1.2	0.0	1.6	0.0	-0.4	-1.8	0.6	-0.1	1.6	1.2	0.5
Peak expiratory flow (PEF)	0.4	1.0	5.2	0.1	-1.2	0.1	-1.3	1.9	-2.3	-1.3	-1.0	-0.7	-0.1	-0.7	-0.4	-0.1	-1.5	0.6	-0.1	0.8	-0.2	1.0	0.4
Loud music exposure frequency	0.4	0.4	1.3	-0.6	0.9	0.2	1.0	-0.2	0.7	0.9	0.3	-0.1	-0.5	-0.3	0.6	1.2	1.1	-0.4	0.9	-0.5	0.1	0.6	-0.2
Blood clot in the leg (DVT)	0.4	0.6	3.6	0.6	0.4	0.3	0.6	0.5	0.4	0.5	1.9	1.7	0.5	0.8	-0.0	0.1	0.5	1.3	-0.4	0.3	0.2	-0.5	-0.1
Headache pain in last month	0.4	0.6	3.7	-0.4	-0.9	-1.2	0.4	-0.3	0.7	-0.5	1.1	0.5	-0.3	-0.3	-0.6	-0.4	-0.1	-0.2	0.3	-1.7	0.0	-0.1	-1.9
Medication: Amlodipine	0.4	0.6	2.5	1.3	0.4	-0.7	0.1	-1.4	-0.7	0.3	-0.6	-0.2	-1.0	0.2	0.9	0.5	0.2	-1.6	0.8	0.3	0.9	0.8	0.5
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.8	0.8	-0.7	-0.4	-0.4	0.4	-1.3	-0.2	-0.3	0.4	-0.8	0.7	-0.6	0.8	-0.6	-0.6	-0.4	1.3	-0.2	0.1	0.4
Forced vital capacity (FVC), Best measure	0.4	1.5	7.3	0.3	1.0	2.7	-0.3	1.7	-0.0	0.5	1.1	-0.4	1.4	1.0	-0.1	0.7	-0.2	2.0	-0.0	2.2	0.3	1.0	1.8
Body fat percentage	0.4	1.5	5.9	0.5	1.2	0.2	1.8	0.6	1.5	1.6	1.1	2.4	0.7	0.8	0.8	1.5	1.8	1.2	1.6	-0.4	-0.6	0.4	-0.4
Leg fat percentage (right)	0.4	1.3	3.8	0.8	0.5	-0.1	1.8	-0.2	1.9	1.4	0.3	1.7	1.0	-0.1	0.5	0.3	1.9	0.5	1.0	-1.3	-1.6	-0.8	-1.5
Number of full brothers	0.4	0.6	4.5	0.7	0.3	-1.0	0.3	-1.0	-0.6	0.1	-1.0	0.7	-1.3	0.2	0.2	-0.3	0.0	-2.1	0.4	-0.3	0.5	-0.1	0.4
Wheeze or whistling in the chest in last year	0.4	0.7	3.0	1.5	0.3	0.3	0.7	0.4	0.0	0.6	-1.7	1.6	0.0	0.2	0.7	1.3	0.2	-0.5	-0.8	0.8	-0.5	-0.4	0.6
Number of children fathered	0.4	0.5	2.0	-0.6	0.5	-0.3	-0.1	0.4	1.0	0.5	1.4	0.7	0.5	0.2	0.2	0.8	0.6	0.1	0.9	0.7	1.0	1.0	0.2
Pulse wave peak to peak time	0.4	0.5	2.8	-0.1	0.3	1.1	1.1	-0.9	0.2	0.8	0.2	-0.6	0.8	0.9	1.7	0.2	0.9	0.5	-0.1	0.3	-0.7	-0.2	-0.5
Whole body fat mass	0.4	1.5	6.2	-0.2	1.1	0.5	1.4	1.2	1.0	1.4	1.7	2.5	1.6	0.8	1.2	1.1	1.5	1.3	1.3	-0.7	-0.4	0.5	-0.5
Leg fat mass (right)	0.4	1.4	3.9	0.0	0.7	0.2	1.6	0.8	1.5	1.3	1.4	2.0	1.9	0.1	0.9	0.2	1.8	1.0	1.1	-1.3	-1.0	-0.3	-1.3
Number of full sisters	0.4	0.5	1.6	-0.1	-0.6	-0.0	0.2	-0.5	-1.2	-0.3	-1.3	-0.4	-0.4	-0.5	-1.0	-0.3	-0.0	-1.0	-0.2	-1.2	-0.1	-0.4	-0.9
Overall health rating	0.4	0.9	2.6	0.1	1.1	0.0	0.8	-0.7	-0.0	1.0	1.6	1.3	-0.0	1.6	1.4	1.5	0.8	-1.4	-0.2	0.1	-0.1	-0.2	0.4
Leg pain on walking	0.4	0.5	2.6	0.5	0.7	0.3	0.5	0.3	0.8	0.6	1.0	1.6	-0.5	0.7	0.0	0.6	0.3	0.0	0.2	1.0	0.2	0.2	1.0
Supplements: Vitamin C	0.4	0.5	1.7	-0.7	-0.2	0.6	-1.3	0.8	0.5	-0.6	-0.2	0.2	-0.5	0.0	-0.9	0.2	-0.9	0.6	-0.9	1.2	-0.4	-0.1	1.0
Whole body fat-free mass	0.4	2.0	9.5	-1.8	0.6	0.3	-0.4	3.0	-1.5	-0.1	2.4	1.3	3.1	0.7	1.9	-0.1	-0.3	0.5	0.7	-0.1	1.2	1.3	0.5
Leg fat-free mass (right)	0.4	2.3	7.8	-2.2	0.5	-0.1	-0.7	2.8	-1.6	-0.3	2.2	1.6	2.2	0.7	1.9	0.3	-0.6	0.4	1.4	0.1	2.1	2.2	0.8
Ever had bowel cancer screening	0.4	0.5	1.5	1.2	-0.5	-1.0	-0.6	-0.9	-0.5	-1.0	-0.9	-0.8	-0.6	-0.0	-0.4	-0.4	-0.9	0.3	-0.7	0.4	0.2	-0.4	0.2
Qualifications: nursing, teaching	0.4	0.6	1.8	0.9	0.2	0.8	-1.1	0.9	0.9	-0.3	-0.4	0.1	0.8	-0.6	-0.8	-1.0	-0.2	0.9	-1.4	0.1	-0.0	-0.9	0.7
Commuting to job workplace: Walk	0.4	0.4	1.6	-0.7	-0.2	0.4	0.1	-0.8	0.7	0.0	0.8	-0.6	-0.7	-1.0	0.6	-0.9	0.5	0.1	0.9	-1.2	0.1	0.5	-0.6
Mineral and other dietary supplements	0.4	0.6	1.7	-1.0	-1.0	-0.6	-0.2	-0.3	-0.2	-0.8	-0.3	-1.0	-0.1	-1.0	0.5	-0.9	-0.6	-1.2	0.5	-0.9	0.3	0.6	-1.3
Asthma (self-reported)	0.4	0.8	3.0	1.7	0.9	0.8	0.9	0.9	-0.1	1.1	-0.6	0.8	-0.1	0.6	0.4	1.2	0.7	0.7	-1.3	0.7	-0.2	-1.1	0.8
Leg predicted mass (right)	0.4	2.3	8.1	-2.2	0.5	-0.1	-0.7	2.9	-1.6	-0.3	2.2	1.6	2.2	0.7	1.9	0.3	-0.6	0.4	1.4	0.1	2.1	2.3	0.9
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.8	-0.4	-1.3	-0.3	-0.6	1.0	-0.9	-0.9	0.4	-0.2	0.1	-0.5	-0.3	-0.4	-1.0	-0.7	-0.6	-0.8	-0.9	0.1	-0.8
Basal metabolic rate	0.4	2.0	9.2	-1.6	0.7	0.3	-0.2	3.0	-1.1	0.1	2.4	1.6	2.9	0.8	1.8	0.3	-0.0	0.8	0.8	-0.1	1.1	1.4	0.5
Unable to work because of sickness or disability	0.4	0.5	3.3	-0.1	0.3	0.3	0.6	-1.8	0.9	0.6	0.1	0.1	-1.7	0.4	0.1	0.3	0.8	-0.7	-0.0	-0.5	-0.0	-0.1	-0.4
Basal cell carcinoma (self-reported)	0.4	0.5	2.2	-0.3	-0.3	-0.8	0.5	-1.3	1.1	-0.1	-0.5	-0.4	-1.5	-0.3	-1.0	-0.1	0.0	-1.0	0.7	-0.5	-0.3	-0.1	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	3.1	0.8	0.3	0.1	0.6	0.5	0.1	0.5	1.8	1.6	0.4	0.7	-0.2	0.1	0.5	1.3	-0.4	0.5	0.1	-0.5	-0.0
Depression (Nagel 2018)	0.3	0.4	1.5	-0.4	-0.6	-1.2	-0.3	-0.7	-0.3	-0.6	0.3	0.1	-0.5	-0.2	1.2	0.1	-0.5	-1.2	0.6	-0.5	0.2	0.6	-0.3
Intelligence (Savage-Jansen 2018)	0.3	0.8	3.1	1.3	0.1	0.4	-0.2	0.4	0.3	0.2	-1.2	-0.7	1.0	-0.4	-1.4	-0.7	0.2	1.8	-1.5	1.0	-0.7	-0.9	0.1
Rheumatoid Arthritis	0.3	0.4	1.6	-0.1	-0.5	0.0	-0.8	0.9	-0.8	-0.6	0.3	0.5	1.3	-0.5	-0.2	-0.1	-0.6	-0.9	-0.7	0.0	-0.9	-0.4	0.0
Neuroticism	0.3	0.7	2.9	-0.3	0.9	0.3	0.7	-0.1	-1.0	0.8	0.7	1.3	-0.2	1.1	1.2	1.7	0.5	-0.2	0.6	1.0	0.8	0.9	0.9
Sensitivity / hurt feelings	0.3	0.4	1.2	0.0	0.2	-1.0	0.6	-0.2	-0.8	0.2	1.1	0.8	-0.2	0.8	0.9	0.9	0.1	-0.5	0.9	-0.0	1.0	0.6	-0.2
Leg fat-free mass (left)	0.3	1.8	7.5	-1.8	0.4	0.2	-0.6	2.7	-1.4	-0.3	2.0	1.4	2.5	0.5	1.8	0.1	-0.5	0.8	1.1	-0.1	1.4	1.8	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	2.6	1.1	-0.1	-0.1	0.3	-0.0	-0.2	-0.0	0.7	0.1	1.0	-0.1	1.6	0.6	0.1	-0.3	0.1	-0.5	-0.6	0.2	-0.4
Medication: Atenolol	0.3	0.4	1.4	0.6	-0.6	0.0	-0.4	-0.6	-0.6	-0.8	1.2	-1.1	-1.0	-0.1	-0.7	-0.2	-1.1	0.2	0.1	0.6	-0.4	0.1	0.4
Body mass index (BMI)	0.3	1.1	4.2	-0.9	0.2	-1.1	0.7	0.0	0.9	0.4	1.2	1.8	0.7	-0.2	1.5	-0.1	0.9	-0.5	2.0	-1.7	0.4	1.0	-1.3
Waist circumference	0.3	1.0	6.7	-0.4	0.6	-0.2	1.1	1.2	0.3	0.9	1.7	2.6	0.9	0.9	0.2	1.0	1.1	0.6	0.9	-0.7	-0.5	0.1	-0.5
Number of incorrect matches in round	0.3	0.5	1.5	0.8	1.2	0.1	0.9	-0.5	0.5	1.2	-0.6	0.5	0.6	0.4	1.0	0.9	1.2	-0.3	-0.4	0.1	-0.1	-0.8	0.5
Alcohol usually taken with meals	0.3	0.6	5.2	0.2	0.3	0.5	0.7	-0.4	-0.0	0.5	1.8	-0.2	0.1	0.2	-0.2	0.4	0.6	2.3	0.2	0.4	0.5	-0.0	-0.4
Nervous feelings	0.3	0.6	4.0	-0.4	0.5	2.0	0.4	-0.5	0.3	0.5	1.0	-0.5	0.5	1.3	0.4	0.3	0.2	-0.6	-1.3	0.7	-0.4	-1.1	0.5
Pain all over the body in last month	0.3	0.3	2.3	-1.5	-0.1	1.0	0.1	-0.6	-0.3	-0.1	0.0	-0.9	0.5	-0.3	0.6	0.1	0.2	-0.6	0.1	-0.7	-0.3	0.1	-0.4
Arm fat percentage (right)	0.3	1.1	5.4	0.2	0.9	0.3	1.4	0.4	1.3	1.2	1.1	2.3	0.4	0.7	0.6	1.1	1.3	1.8	1.5	-0.3	-0.3	0.6	-0.3
Trunk fat-free mass	0.3	2.0	11.6	-1.3	0.8	0.6	-0.3	3.1	-1.4	0.1	2.5	1.2	3.4	1.0	1.8	-0.1	-0.1	0.6	0.2	0.0	0.8	0.8	0.6
Worrier / anxious feelings	0.3	0.7	2.4	0.1	0.4	1.1	0.7	-0.0	-0.9	0.5	1.5	1.4	-0.5	1.5	0.4	0.7	0.4	-0.6	-0.7	-0.3	-0.8	-0.9	0.1
Hair/balding pattern: Pattern 3	0.3	0.5	2.2	1.1	0.6	0.2	0.1	0.2	0.3	-0.1	1.1	-0.8	1.3	-0.5	1.0	-0.1	0.2	1.5	-0.4	-0.3	-0.2	-0.3	0.1
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	6.2	0.1	0.2	1.8	-0.5	2.5	-1.3	-0.1	-0.1	-0.7	0.9	0.9	-0.3	0.6	-0.7	1.0	-0.2	1.6	0.4	0.9	1.3
Pulse rate	0.3	0.5	3.0	-0.6	-0.3	0.5	-0.3	1.1	1.7	-0.0	-0.6	0.4	0.5	-0.4	-1.4	0.2	-0.0	0.0	-0.9	0.2	-0.7	-1.0	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	3.3	0.2	0.6	1.8	-0.4	1.5	-0.1	0.2	0.8	-0.7	1.0	0.9	-0.6	0.3	-0.3	1.8	0.2	1.6	0.5	1.0	1.4
Arm fat mass (right)	0.3	1.1	5.1	-0.5	0.8	0.1	0.9	1.3	0.8	0.8	1.5	2.3	1.2	0.7	0.9	0.9	0.9	1.3	1.6	-0.4	0.2	0.9	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.2	-0.3	0.8	0.5	0.6	-1.0	0.0	0.7	0.0	0.2	-0.9	1.1	0.6	0.7	0.6	-0.1	0.8	0.6	0.2	0.7	0.6
Arm fat-free mass (right)	0.3	1.7	8.8	-1.6	0.6	-0.4	-0.4	2.5	-1.1	0.0	2.4	0.7	3.0	0.5	2.0	-0.4	0.1	-0.4	0.9	-0.7	1.3	1.2	0.1
Health satisfaction	0.3	0.3	2.3	-0.1	0.4	0.0	0.3	-0.1	-1.5	0.4	0.0	0.1	-1.0	0.8	0.9	0.6	0.1	-0.7	-0.1	0.5	0.2	0.3	0.5
Medication: Ibuprofen	0.3	0.4	1.8	0.0	-0.3	-1.4	-0.8	0.2	-0.1	-0.7	-0.4	-0.3	-0.7	-0.2	-0.2	0.1	-0.8	-0.2	0.7	0.5	0.6	1.1	0.5
Medication: Allopurinol	0.3	0.4	1.9	-0.8	0.0	-0.8	-0.0	-0.6	-0.4	-0.1	-1.4	-0.9	-0.4	-0.1	-0.8	0.1	0.1	-0.3	1.1	-0.3	0.2	0.8	-0.0
Arm predicted mass (right)	0.3	1.8	8.6	-1.6	0.6	-0.6	-0.0	2.2	-1.0	0.2	2.5	0.9	2.9	0.5	2.2	-0.4	0.3	-0.5	1.1	-1.0	1.2	1.2	-0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	2.3	-0.1	0.1	1.5	0.1	0.0	-0.6	0.2	-0.2	-1.0	-0.1	-0.1	-0.5	-0.1	0.1	-0.3	-1.0	0.5	-0.4	-0.8	0.4
Hypertension (Self-reported)	0.3	0.8	4.8	0.5	0.7	0.4	1.1	-2.0	0.4	0.8	1.1	-0.6	0.4	0.2	2.2	0.4	1.0	0.3	1.1	-0.3	-0.6	0.4	-0.0
Arm fat percentage (left)	0.3	1.3	6.3	-0.3	0.8	-0.1	1.2	0.2	1.1	1.1	1.1	2.5	0.2	0.7	1.1	1.1	1.2	1.2	2.3	-0.4	0.3	1.3	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.4	-1.2	-0.0	-0.8	0.4	0.9	0.0	0.2	-0.4	1.2	0.0	0.3	-0.4	0.4	0.3	-1.0	0.6	-1.2	0.8	0.6	-0.5
Osteoporosis (self-reported)	0.3	0.4	3.1	-0.2	0.2	-0.2	0.4	-0.8	1.7	0.1	-0.8	-0.6	-0.3	-0.5	-0.7	0.0	0.4	0.2	0.2	-0.1	-1.1	-0.6	-0.3
Whole body water mass	0.3	1.8	8.5	-1.6	0.5	0.2	-0.5	2.9	-1.5	-0.2	2.4	1.1	2.9	0.7	1.8	-0.1	-0.3	0.4	0.6	-0.1	1.2	1.2	0.5
Arm fat mass (left)	0.3	1.1	5.6	-0.6	0.7	0.1	0.8	1.2	0.6	0.8	1.4	2.4	1.1	0.7	1.1	0.8	0.9	1.1	1.7	-0.5	0.2	1.1	-0.3
Average weekly champagne plus white wine intake	0.3	0.4	3.4	-0.1	0.2	0.6	-0.2	-0.1	0.4	-0.3	0.9	-0.5	-0.1	0.3	-1.4	-0.2	-0.4	1.8	-0.4	0.9	-0.2	-0.3	0.5
Alcohol drinker status: Never	0.3	0.3	1.4	0.3	0.7	-0.4	0.1	0.8	-0.0	0.5	-1.2	0.4	-0.1	0.5	-0.6	0.7	0.3	0.1	0.2	0.8	0.3	0.4	0.8
Leg fat percentage (left)	0.3	1.1	3.3	0.3	0.5	-0.5	1.8	-0.2	1.6	1.3	0.5	1.8	0.6	0.1	0.4	0.6	1.8	0.0	1.2	-1.3	-1.1	-0.3	-1.4
Arm fat-free mass (left)	0.3	1.4	8.5	-1.1	0.9	-0.1	0.2	2.6	-0.9	0.4	2.1	1.0	2.9	0.6	1.6	-0.0	0.5	0.1	0.6	-0.6	0.7	0.7	0.1
Myopia	0.3	0.4	2.9	-1.0	0.6	0.4	0.5	-0.6	-0.3	0.5	-0.1	1.0	-0.3	0.8	1.7	0.6	0.3	0.3	0.6	0.4	0.5	0.3	0.5
Vascular/heart problems diagnosed by doctor	0.3	0.7	4.1	-0.6	-0.5	-0.9	-1.0	2.0	-0.2	-0.7	-1.0	0.8	-0.2	-0.1	-1.5	-0.3	-0.9	-0.5	-0.4	0.3	1.3	0.2	0.1
Pain experienced in last month	0.3	0.5	2.2	0.0	0.2	-0.0	-0.1	0.2	-0.1	0.1	-1.5	-1.2	1.2	-1.0	1.1	-0.9	0.3	0.3	0.6	0.2	0.2	0.4	0.3
Leg fat mass (left)	0.3	1.2	4.2	-0.2	0.7	-0.2	1.4	0.8	1.3	1.2	1.5	2.0	1.6	0.2	0.8	0.4	1.6	0.7	1.3	-1.3	-0.6	0.2	-1.2
Arm predicted mass (left)	0.3	1.5	9.8	-0.8	1.1	0.3	0.3	2.7	-0.8	0.5	2.1	1.0	3.1	0.7	1.4	0.1	0.6	0.5	0.1	-0.5	0.4	0.3	0.3
Blood Platelet Count	0.2	2.1	10.6	0.4	-1.0	-1.3	-1.8	-1.3	-2.3	-1.6	-3.2	-1.3	-0.8	-0.5	-0.1	-1.5	-1.6	-1.9	-0.7	-0.0	2.1	-0.0	0.1
Cardiovascular Disease	0.2	0.8	4.7	0.7	0.1	-0.6	0.2	-2.1	-0.7	0.0	0.9	-0.9	-0.9	-0.4	2.2	0.3	0.1	-0.4	1.1	-0.5	-0.2	1.0	-0.1
Medication: Co-codamol	0.2	0.3	1.0	0.8	-0.1	0.1	0.2	-1.0	0.2	0.1	-0.9	0.0	-1.0	0.1	0.1	-0.4	0.1	-0.8	-0.3	-0.6	0.1	-0.3	-0.4
High blood pressure	0.2	0.6	4.0	0.3	0.4	0.4	0.7	-1.7	-0.1	0.5	0.6	-0.7	0.0	0.3	2.0	0.5	0.6	0.1	1.1	-0.1	-0.5	0.7	0.2
Hearing difficulty/problems with background noise	0.2	0.4	1.4	-0.0	-0.6	-0.6	-0.6	-0.7	1.2	-0.2	-0.9	1.0	-0.5	0.2	0.1	-0.3	-0.3	0.8	0.7	0.2	-0.4	0.7	-0.6
Had menopause	0.2	0.2	0.7	0.8	-0.2	-0.6	0.1	0.5	-0.3	-0.3	-0.0	-0.1	-0.4	0.6	-0.3	0.5	-0.3	-0.3	-0.8	0.2	0.4	-0.7	0.1
Shortness of breath walking on level ground	0.2	0.2	0.5	-0.5	0.2	-0.6	-0.2	-0.2	0.4	-0.1	0.6	0.5	-0.7	0.0	0.5	-0.4	-0.2	-0.7	0.2	0.5	0.7	0.1	0.5
Emphysema/chronic bronchitis	0.2	0.3	1.4	-0.6	-0.4	0.5	0.1	0.4	-0.3	0.1	0.7	1.2	0.2	0.1	0.9	-0.0	0.1	0.2	-0.3	0.3	-1.1	-0.3	-0.2
Heart disease (mother)	0.2	0.3	1.5	1.1	0.2	-0.4	0.9	-1.2	-0.0	0.3	0.1	-0.8	-0.4	-0.7	-0.0	-0.3	0.3	0.5	0.1	-0.0	0.4	-0.3	-0.3
Pulse rate, automated reading	0.2	0.6	3.0	-0.7	-0.4	-0.2	-1.2	0.6	1.7	-0.4	0.1	1.5	-0.0	0.2	-0.4	0.5	-0.6	-0.7	-1.3	1.0	-0.3	-0.6	0.5
Suffer from ‘nerves’	0.2	0.4	2.1	0.7	0.4	0.3	0.8	-1.5	0.1	0.4	1.0	-0.6	-0.2	0.9	0.8	0.6	0.4	-0.5	0.2	-0.3	0.5	0.2	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.6	-0.5	0.3	0.9	0.4	-0.8	1.2	0.2	1.1	-0.8	0.2	0.7	-0.6	-0.2	0.4	1.0	1.0	0.1	-0.1	0.7	0.1
Medication: Blood pressure	0.2	0.3	1.4	-0.3	0.3	0.3	0.3	-0.2	-1.2	0.4	-0.5	0.5	-0.5	1.1	-0.1	0.9	0.2	-0.6	0.2	0.5	0.7	0.4	0.7
Illnesses of father: High blood pressure	0.2	0.2	1.1	-0.9	-0.5	0.3	-0.2	-0.3	0.1	-0.2	-1.0	-0.2	0.2	-0.3	-0.0	-0.0	-0.3	-0.6	-0.4	-0.2	-0.3	-0.4	-0.5
Alcohol drinker status: Previous	0.2	0.3	1.5	0.3	0.1	0.8	-0.1	-0.7	-0.5	0.2	-0.4	0.6	-0.8	0.4	-0.4	0.1	0.2	-0.0	-1.2	0.2	-0.6	-0.7	0.0
Bipolar Disorder (2011)	0.1	0.1	0.9	0.0	0.3	0.0	0.4	0.6	0.0	0.3	0.0	0.0	-0.4	0.0	0.5	0.9	0.2	0.3	0.0	-0.0	0.0	0.0	0.0
Blood Red Count	0.1	1.3	12.2	0.1	0.5	-0.5	1.3	-1.1	1.7	0.8	1.4	0.4	0.4	-0.6	3.5	0.6	1.1	-0.3	1.1	-0.6	-1.1	-0.3	-0.4
Blood White Count	0.1	0.5	2.9	1.7	0.2	-1.6	0.4	0.4	1.0	0.1	0.7	0.8	0.8	0.0	-0.9	0.1	0.3	0.1	0.7	-0.1	0.3	-0.1	-0.1
BMI	0.1	0.7	1.9	-0.1	-0.3	-1.2	0.4	-0.0	1.2	0.1	1.1	1.3	0.3	-0.6	1.1	0.1	0.5	-0.8	1.4	-1.3	0.1	0.7	-1.2
Tanning	0.1	0.9	3.6	0.2	-0.9	-0.2	-0.1	-1.6	0.8	-0.3	-0.6	-1.1	-1.9	-0.8	-0.9	-0.9	-0.0	-1.0	-0.7	-0.6	-1.2	-1.2	-1.0
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.3	0.2	-0.0	-0.2	0.0	-0.8	0.3	0.1	0.4	0.4	-0.1	0.4	1.1	0.8	0.1	-0.5	0.1	-0.1	-0.1	0.4	-0.0
Hair Pigment	0.0	1.0	7.3	1.0	0.8	0.2	0.7	-0.4	2.3	0.7	2.7	0.8	0.3	0.9	0.4	1.1	0.5	0.1	0.3	0.8	0.1	0.1	0.3

Hub : Genes

PRKRIP1

Models

Trait associations