[Hub]/) : Traits : Sitting height : ← →

chr11:46,010,847-48,783,497

Best TWAS P=3.92e-27 · Best GWAS P=4.52e-27 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FAM180B	0.07	0.08	lasso	3	0.08	9.1e-10	-8.1	-9.0	2.3e-19	0.91	0.07	0.93	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MTCH2	0.03	0.00	bslmm	299	0.00	1.1e-01	5.1	-9.6	7.6e-22	0.74	0.03	0.78	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PSMC3	0.04	0.00	enet	22	0.01	3.8e-02	5.2	-5.8	4.8e-09	0.55	0.06	0.65	FALSE
4	GTEx	Adipose Subcutaneous	ACP2	0.08	0.03	enet	18	0.03	3.5e-03	5.1	-5.5	4.0e-08	0.54	0.28	0.23	FALSE
5	GTEx	Adipose Subcutaneous	C1QTNF4	0.16	0.22	lasso	4	0.22	2.5e-18	-8.0	8.8	1.5e-18	-0.90	0.55	0.45	FALSE
6	GTEx	Adipose Visceral Omentum	ARHGAP1	0.12	0.02	enet	15	0.04	3.8e-03	4.6	-5.9	4.7e-09	0.12	0.05	0.60	FALSE
7	GTEx	Artery Aorta	PACSIN3	0.10	0.04	lasso	4	0.03	1.1e-02	3.6	6.0	1.6e-09	-0.27	0.35	0.08	FALSE
8	GTEx	Artery Aorta	C1QTNF4	0.09	0.10	lasso	1	0.08	3.2e-05	-8.1	8.1	6.7e-16	-0.85	0.05	0.92	FALSE
9	GTEx	Brain Cerebellar Hemisphere	MADD	0.44	0.14	lasso	7	0.21	4.0e-06	5.1	-5.7	1.2e-08	0.43	0.21	0.48	TRUE
10	GTEx	Brain Cerebellum	MADD	0.21	0.00	enet	13	0.11	3.3e-04	1.2	-5.7	1.4e-08	0.59	0.12	0.44	FALSE
11	GTEx	Brain Cortex	MTCH2	0.21	0.19	lasso	6	0.16	4.0e-05	-10.8	-10.5	1.3e-25	0.98	0.01	0.98	FALSE
12	GTEx	Brain Cortex	C1QTNF4	0.26	0.04	lasso	8	0.02	1.2e-01	7.4	8.2	2.5e-16	-0.78	0.03	0.42	FALSE
13	GTEx	Brain Putamen basal ganglia	CKAP5	0.25	0.07	lasso	3	0.14	4.4e-04	2.0	5.2	2.6e-07	-0.43	0.02	0.66	FALSE
14	GTEx	Breast Mammary Tissue	C1QTNF4	0.10	0.06	lasso	2	0.03	8.5e-03	-9.1	9.0	1.7e-19	-0.89	0.04	0.87	FALSE
15	GTEx	Breast Mammary Tissue (Female)	MADD	0.13	0.04	lasso	3	0.05	1.3e-02	-9.1	-9.0	1.5e-19	0.87	0.04	0.53	FALSE
16	GTEx	Cells Transformed fibroblasts	FNBP4	0.11	0.05	lasso	8	0.08	1.6e-06	7.3	-8.7	2.7e-18	0.84	0.28	0.72	FALSE
17	GTEx	Cells Transformed fibroblasts	PSMC3	0.07	0.00	enet	13	0.02	2.3e-02	4.9	-8.0	9.7e-16	0.79	0.04	0.68	FALSE
18	GTEx	Cells Transformed fibroblasts	C1QTNF4	0.13	0.11	enet	19	0.12	5.2e-09	-10.5	7.8	6.2e-15	-0.84	0.03	0.97	FALSE
19	GTEx	Cells Transformed fibroblasts	NDUFS3	0.08	0.01	lasso	2	0.01	3.3e-02	-8.0	8.4	2.8e-17	-0.83	0.03	0.84	FALSE
20	GTEx	Colon Transverse	C1QTNF4	0.07	0.02	lasso	6	0.03	2.0e-02	-8.0	9.4	6.6e-21	-0.93	0.02	0.93	FALSE
21	GTEx	Esophagus Gastroesophageal Junction	NUP160	0.18	0.02	enet	18	0.11	7.1e-05	3.0	-7.0	3.7e-12	0.57	0.12	0.57	FALSE
22	GTEx	Esophagus Gastroesophageal Junction	CKAP5	0.11	0.04	lasso	3	0.03	2.1e-02	5.5	5.7	1.3e-08	-0.24	0.10	0.66	FALSE
23	GTEx	Esophagus Mucosa	ARFGAP2	0.05	0.06	lasso	4	0.05	4.4e-04	5.5	5.4	6.8e-08	-0.14	0.32	0.03	FALSE
24	GTEx	Esophagus Mucosa	PACSIN3	0.24	0.19	lasso	8	0.21	7.5e-14	4.5	5.3	8.8e-08	-0.25	1.00	0.00	FALSE
25	GTEx	Esophagus Mucosa	C1QTNF4	0.10	0.11	lasso	1	0.10	5.0e-07	-8.1	8.1	6.7e-16	-0.85	0.13	0.86	FALSE
26	GTEx	Esophagus Muscularis	MTCH2	0.09	0.04	lasso	6	0.02	1.8e-02	-10.5	-9.5	2.6e-21	0.89	0.02	0.96	FALSE
27	GTEx	Esophagus Muscularis	C1QTNF4	0.10	0.05	enet	23	0.06	1.4e-04	-8.0	9.6	1.2e-21	-0.86	0.08	0.90	FALSE
28	GTEx	Heart Atrial Appendage	C1QTNF4	0.26	0.14	lasso	9	0.17	3.9e-08	-8.1	9.1	7.6e-20	-0.90	0.04	0.96	FALSE
29	GTEx	Heart Left Ventricle	C1QTNF4	0.10	0.11	lasso	1	0.09	1.1e-05	-8.1	8.1	6.7e-16	-0.85	0.20	0.42	FALSE
30	GTEx	Liver	PSMC3	0.15	0.09	lasso	4	0.07	5.9e-03	-7.5	-9.0	1.6e-19	0.68	0.03	0.65	FALSE
31	GTEx	Liver	C1QTNF4	0.25	0.14	enet	16	0.20	2.3e-06	-8.1	7.5	6.8e-14	-0.83	0.03	0.94	FALSE
32	GTEx	Lung	PSMC3	0.07	0.02	lasso	2	0.03	3.6e-03	5.2	-5.6	2.7e-08	0.29	0.18	0.10	FALSE
33	GTEx	Lung	C1QTNF4	0.18	0.15	lasso	6	0.13	3.2e-10	-9.0	9.6	6.5e-22	-0.93	0.04	0.96	FALSE
34	GTEx	Muscle Skeletal	MTCH2	0.05	0.03	enet	15	0.04	1.5e-04	-10.1	-9.3	1.4e-20	0.92	0.04	0.95	FALSE
35	GTEx	Muscle Skeletal	C1QTNF4	0.09	0.14	lasso	3	0.13	9.9e-13	-8.1	9.1	6.6e-20	-0.92	0.08	0.92	FALSE
36	GTEx	Muscle Skeletal	ARHGAP1	0.03	0.05	lasso	2	0.04	1.2e-04	5.5	-5.5	4.2e-08	0.10	0.01	0.99	FALSE
37	GTEx	Nerve Tibial	LRP4	0.28	0.24	enet	24	0.30	3.5e-21	-4.7	5.4	5.6e-08	-0.33	1.00	0.00	FALSE
38	GTEx	Nerve Tibial	PTPRJ	0.05	0.03	enet	13	0.03	2.7e-03	4.1	5.8	7.2e-09	-0.56	0.13	0.37	FALSE
39	GTEx	Nerve Tibial	SLC39A13	0.07	0.01	enet	14	0.02	7.6e-03	-9.1	-8.6	8.3e-18	0.69	0.13	0.33	FALSE
40	GTEx	Nerve Tibial	C1QTNF4	0.20	0.23	enet	12	0.23	1.7e-16	-8.1	8.3	9.5e-17	-0.88	0.80	0.20	TRUE
41	GTEx	Pancreas	LRP4	0.11	0.10	enet	16	0.14	1.8e-06	5.5	-5.3	1.2e-07	0.16	0.92	0.00	FALSE
42	GTEx	Pancreas	LRP4-AS1	0.10	0.08	lasso	6	0.12	1.4e-05	5.5	-6.0	2.2e-09	0.23	0.78	0.01	FALSE
43	GTEx	Pituitary	MADD	0.42	0.32	lasso	6	0.39	8.9e-11	1.9	-6.4	1.3e-10	0.69	0.04	0.95	FALSE
44	GTEx	Prostate	PSMC3	0.21	0.10	lasso	6	0.20	7.9e-06	5.0	-7.3	2.4e-13	0.48	0.15	0.10	FALSE
45	GTEx	Skin Not Sun Exposed Suprapubic	LRP4	0.13	0.00	lasso	7	0.02	3.5e-02	5.7	9.2	4.0e-20	-0.60	0.03	0.76	FALSE
46	GTEx	Skin Not Sun Exposed Suprapubic	DDB2	0.07	0.02	enet	13	0.04	3.5e-03	5.1	5.9	3.2e-09	-0.21	0.15	0.04	FALSE
47	GTEx	Skin Not Sun Exposed Suprapubic	PACSIN3	0.11	0.05	lasso	3	0.10	3.4e-06	4.5	5.8	6.4e-09	-0.25	0.63	0.02	FALSE
48	GTEx	Skin Not Sun Exposed Suprapubic	C1QTNF4	0.32	0.18	enet	33	0.20	5.2e-11	-8.1	7.4	1.8e-13	-0.80	0.13	0.87	FALSE
49	GTEx	Skin Sun Exposed Lower leg	ACP2	0.16	0.14	enet	15	0.15	1.8e-12	5.2	-6.8	1.3e-11	0.43	1.00	0.00	FALSE
50	GTEx	Skin Sun Exposed Lower leg	PACSIN3	0.17	0.11	lasso	4	0.12	5.5e-10	4.5	5.7	1.2e-08	-0.23	1.00	0.00	FALSE
51	GTEx	Skin Sun Exposed Lower leg	PSMC3	0.20	0.05	lasso	7	0.10	1.2e-08	4.9	-8.1	5.0e-16	0.69	0.64	0.34	FALSE
52	GTEx	Skin Sun Exposed Lower leg	C1QTNF4	0.25	0.22	lasso	12	0.23	4.2e-19	-8.1	9.4	5.4e-21	-0.90	0.12	0.88	FALSE
53	GTEx	Skin Sun Exposed Lower leg	ARHGAP1	0.08	0.01	lasso	5	0.02	1.4e-02	5.5	-6.0	2.4e-09	0.14	0.02	0.94	TRUE
54	GTEx	Spleen	C1QTNF4	0.31	0.28	enet	29	0.34	1.8e-09	-10.8	10.5	1.1e-25	-0.94	0.02	0.98	FALSE
55	GTEx	Testis	NR1H3	0.10	0.10	lasso	6	0.08	2.9e-04	5.5	-5.5	4.0e-08	0.33	0.61	0.02	FALSE
56	GTEx	Testis	MTCH2	0.17	0.16	lasso	3	0.16	1.0e-07	-9.1	-9.1	1.1e-19	0.89	0.08	0.92	FALSE
57	GTEx	Testis	C1QTNF4	0.14	0.12	lasso	4	0.11	1.6e-05	7.4	6.7	2.5e-11	-0.66	0.72	0.15	FALSE
58	GTEx	Thyroid	PACSIN3	0.14	0.09	lasso	3	0.09	2.9e-07	4.5	5.2	2.6e-07	-0.18	0.98	0.00	FALSE
59	GTEx	Whole Blood	C1QTNF4	0.09	0.05	lasso	3	0.03	1.4e-03	-10.8	10.8	3.9e-27	-0.99	0.01	0.98	TRUE
60	METSIM	Adipose	ACP2	0.05	0.04	blup	302	0.06	1.7e-09	-9.1	-7.4	1.3e-13	0.68	0.11	0.89	FALSE
61	METSIM	Adipose	C1QTNF4	0.24	0.31	lasso	7	0.31	1.2e-46	-10.6	10.6	4.6e-26	-0.97	0.05	0.95	FALSE
62	METSIM	Adipose	MYBPC3	0.11	0.10	enet	26	0.11	1.0e-15	-9.1	9.4	8.3e-21	-0.84	0.30	0.70	FALSE
63	METSIM	Adipose	PSMC3	0.06	0.03	enet	28	0.04	2.3e-06	-6.7	-8.4	4.8e-17	0.84	0.05	0.95	TRUE
64	METSIM	Adipose	RAPSN	0.11	0.01	enet	21	0.06	7.9e-09	3.3	7.2	4.3e-13	-0.28	0.85	0.14	FALSE
65	NTR	Blood	MTCH2	0.02	0.04	lasso	1	0.04	1.3e-11	-10.5	10.5	6.8e-26	-0.96	0.02	0.98	FALSE
66	ROSMAP	Brain Pre-frontal Cortex	MTCH2	0.35	0.40	enet	9	0.40	4.7e-56	-10.6	-10.4	3.0e-25	0.97	0.06	0.94	FALSE
67	ROSMAP	Brain Pre-frontal Cortex	FNBP4	0.04	0.04	lasso	3	0.04	8.2e-06	7.4	-6.9	5.8e-12	0.62	0.98	0.02	FALSE
68	ROSMAP	Brain Pre-frontal Cortex	ACP2	0.03	0.00	blup	295	0.02	1.5e-03	-8.9	-7.4	1.7e-13	0.66	0.27	0.38	FALSE
69	ROSMAP	Brain Pre-frontal Cortex	CELF1	0.03	0.01	bslmm	289	0.01	2.9e-02	5.5	7.3	3.0e-13	-0.55	0.16	0.15	FALSE
70	ROSMAP	Brain Pre-frontal Cortex	PSMC3	0.15	0.08	bslmm	285	0.10	5.1e-13	5.2	-8.1	8.0e-16	0.61	0.95	0.05	FALSE
71	ROSMAP	Brain Pre-frontal Cortex	C1QTNF4	0.05	0.06	blup	281	0.06	1.7e-08	-8.9	10.0	1.1e-23	-0.88	0.05	0.95	TRUE
72	YFS	Blood	CKAP5	0.01	0.01	bslmm	291	0.01	3.6e-03	4.5	-5.7	1.1e-08	0.47	0.00	0.85	FALSE
73	YFS	Blood	FNBP4	0.02	0.01	bslmm	301	0.01	8.9e-05	3.7	-5.8	7.4e-09	0.75	0.04	0.94	FALSE
74	YFS	Blood	NR1H3	0.34	0.15	enet	66	0.24	3.1e-76	5.1	-5.7	9.8e-09	0.46	1.00	0.00	FALSE
75	YFS	Blood	NUP160	0.02	0.01	blup	290	0.01	1.7e-04	-10.8	-7.6	2.1e-14	0.80	0.02	0.98	FALSE
76	YFS	Blood	PSMC3	0.02	0.01	blup	289	0.01	2.8e-05	-8.0	-9.0	2.3e-19	0.73	0.30	0.55	FALSE
77	YFS	Blood	PTPMT1	0.03	0.01	lasso	5	0.01	3.2e-04	7.5	7.2	8.5e-13	-0.61	0.38	0.46	FALSE
78	YFS	Blood	SPI1	0.65	0.18	enet	75	0.27	1.6e-87	-8.9	6.1	1.1e-09	-0.70	1.00	0.00	FALSE
79	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1QTNF4	0.06	0.07	lasso	2	0.06	4.9e-06	-10.5	10.1	5.1e-24	-0.96	0.00	1.00	FALSE
80	The Cancer Genome Atlas	Breast Invasive Carcinoma	MYBPC3	0.02	0.01	blup	43	0.01	3.4e-03	-9.0	7.9	2.2e-15	-0.80	0.01	0.97	FALSE
81	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUP160	0.03	0.01	blup	44	0.01	1.9e-03	-10.1	-8.5	2.1e-17	0.84	0.01	0.57	FALSE
82	The Cancer Genome Atlas	Colon Adenocarcinoma	C1QTNF4	0.12	0.12	lasso	1	0.12	1.6e-07	-8.1	8.1	6.7e-16	-0.85	0.03	0.96	FALSE
83	The Cancer Genome Atlas	Colon Adenocarcinoma	KBTBD4	0.14	0.01	blup	13	0.02	1.6e-02	7.5	-8.4	6.0e-17	0.83	0.00	0.51	FALSE
84	The Cancer Genome Atlas	Colon Adenocarcinoma	NUP160	0.05	0.05	blup	44	0.05	7.7e-04	7.4	-7.8	7.4e-15	0.74	0.08	0.23	FALSE
85	The Cancer Genome Atlas	Colon Adenocarcinoma	PSMC3	0.09	0.05	blup	39	0.05	1.0e-03	4.0	-7.8	4.9e-15	0.64	0.02	0.80	FALSE
86	The Cancer Genome Atlas	Esophageal Carcinoma	C1QTNF4	0.39	0.33	blup	15	0.35	6.1e-12	-8.1	9.0	1.6e-19	-0.90	0.01	0.99	FALSE
87	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1QTNF4	0.06	0.08	lasso	3	0.08	7.5e-09	-10.6	10.5	5.1e-26	-0.97	0.00	1.00	FALSE
88	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FNBP4	0.10	0.03	blup	45	0.05	7.7e-06	-10.8	-9.5	1.6e-21	0.82	0.00	0.99	FALSE
89	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MYBPC3	0.05	0.03	blup	43	0.04	6.0e-05	-6.9	8.4	4.0e-17	-0.75	0.02	0.98	FALSE
90	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NUP160	0.08	0.03	blup	42	0.04	6.7e-05	-10.7	-8.9	3.5e-19	0.91	0.01	0.97	FALSE
91	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PSMC3	0.05	0.01	lasso	3	0.02	9.4e-04	4.6	-8.8	1.2e-18	0.67	0.01	0.68	FALSE
92	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1QTNF4	0.12	0.14	enet	4	0.16	6.5e-18	-10.6	9.9	4.3e-23	-0.95	0.00	1.00	FALSE
93	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMC3	0.05	0.04	lasso	3	0.05	3.8e-06	-6.7	-8.2	2.1e-16	0.80	0.01	0.98	FALSE
94	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1QTNF4	0.13	0.16	lasso	1	0.16	3.1e-09	-10.5	10.5	6.8e-26	-0.96	0.00	1.00	FALSE
95	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PSMC3	0.07	0.07	enet	7	0.06	1.4e-04	-9.1	-9.1	6.9e-20	0.88	0.01	0.98	FALSE
96	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACP2	0.09	0.04	enet	12	0.06	5.0e-07	5.1	-5.5	3.0e-08	0.53	0.60	0.38	FALSE
97	The Cancer Genome Atlas	Brain Lower Grade Glioma	MADD	0.08	0.01	lasso	5	0.05	3.1e-06	-8.9	-6.1	9.5e-10	0.60	0.00	0.95	FALSE
98	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTCH2	0.11	0.11	lasso	2	0.10	6.4e-12	-10.6	-10.6	4.2e-26	0.97	0.00	1.00	FALSE
99	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYBPC3	0.03	0.01	blup	43	0.02	3.2e-03	-9.1	9.0	1.8e-19	-0.75	0.00	0.92	TRUE
100	The Cancer Genome Atlas	Brain Lower Grade Glioma	PSMC3	0.10	0.05	blup	39	0.08	3.7e-09	-9.1	-7.6	3.5e-14	0.68	0.02	0.98	FALSE
101	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1QTNF4	0.19	0.19	lasso	3	0.19	3.2e-09	-10.6	10.6	4.2e-26	-0.97	0.00	1.00	FALSE
102	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PSMC3	0.09	0.07	blup	39	0.06	8.7e-04	-9.1	-8.1	6.2e-16	0.86	0.01	0.98	TRUE
103	The Cancer Genome Atlas	Lung Adenocarcinoma	C1QTNF4	0.03	0.02	blup	15	0.02	1.3e-03	-8.1	8.6	8.5e-18	-0.89	0.00	0.96	FALSE
104	The Cancer Genome Atlas	Lung Adenocarcinoma	MYBPC3	0.04	0.02	enet	10	0.04	2.9e-05	-9.0	6.1	1.3e-09	-0.69	0.00	0.98	FALSE
105	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC39A13	0.06	0.01	blup	58	0.04	9.3e-04	4.9	-7.8	5.5e-15	0.58	0.02	0.39	FALSE
106	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARHGAP1	0.05	0.04	blup	26	0.05	1.1e-05	5.5	-5.4	8.2e-08	0.15	0.00	1.00	FALSE
107	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUP160	0.03	0.02	enet	7	0.02	6.3e-03	-10.1	-9.7	3.5e-22	0.94	0.01	0.90	FALSE
108	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMC3	0.02	0.02	blup	39	0.02	5.7e-03	-9.1	-8.3	1.3e-16	0.82	0.01	0.73	FALSE
109	The Cancer Genome Atlas	Soft Tissue Sarcoma	ACP2	0.08	0.06	enet	7	0.06	1.6e-04	3.0	-5.2	1.6e-07	0.27	0.02	0.30	FALSE
110	The Cancer Genome Atlas	Stomach Adenocarcinoma	C1QTNF4	0.06	0.04	lasso	4	0.03	4.3e-03	-10.5	10.2	3.2e-24	-0.96	0.00	0.93	FALSE
111	The Cancer Genome Atlas	Thyroid Carcinoma	C1QTNF4	0.04	0.01	blup	15	0.03	7.9e-04	-8.1	6.5	7.2e-11	-0.80	0.01	0.85	FALSE