[Hub]/) : Traits : Blood Red Count :

chr17:6,652,789-9,227,278

Best TWAS P=5.35e-22 · Best GWAS P=1.57e-21 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CNTROB 0.05 0.01 blup 504 0.01 5.3e-03 5.9 -5.6 1.7e-08 -0.59 0.48 0.24 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100128288 0.32 0.32 lasso 2 0.31 1.2e-38 4.7 -5.2 2.0e-07 -0.03 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex LOC284023 0.10 0.07 bslmm 506 0.07 1.1e-08 3.6 5.3 1.3e-07 0.40 0.97 0.03 FALSE
4 CommonMind Brain Pre-frontal Cortex PFAS 0.10 0.09 lasso 4 0.10 8.9e-13 6.8 8.5 2.7e-17 0.04 0.43 0.57 FALSE
5 GTEx Adipose Subcutaneous KCNAB3 0.09 0.08 lasso 3 0.05 5.8e-05 5.5 -6.4 1.9e-10 -0.72 0.97 0.02 FALSE
6 GTEx Adipose Subcutaneous LSMD1 0.21 0.10 enet 29 0.13 6.6e-11 7.4 5.7 1.6e-08 0.17 0.99 0.00 FALSE
7 GTEx Artery Tibial KDM6B 0.14 0.02 enet 22 0.03 1.4e-03 8.3 -6.5 6.5e-11 -0.24 0.26 0.05 FALSE
8 GTEx Artery Tibial CNTROB 0.16 0.16 lasso 5 0.15 5.2e-12 5.7 -6.0 1.5e-09 -0.69 1.00 0.00 FALSE
9 GTEx Artery Tibial AC135178.1 0.20 0.15 lasso 3 0.20 2.1e-15 4.7 -6.8 1.4e-11 -0.03 1.00 0.00 FALSE
10 GTEx Artery Tibial TNFSF12 0.11 0.06 lasso 2 0.05 1.2e-04 -5.8 -5.8 6.1e-09 -0.03 0.76 0.01 FALSE
11 GTEx Brain Cerebellar Hemisphere KCNAB3 0.54 0.35 lasso 9 0.30 1.9e-08 5.7 -6.3 2.2e-10 -0.70 0.90 0.07 FALSE
12 GTEx Brain Cerebellum KCNAB3 0.34 0.33 lasso 7 0.34 6.8e-11 5.7 -6.5 1.0e-10 -0.72 0.96 0.04 FALSE
13 GTEx Brain Cerebellum AC135178.1 0.54 0.40 lasso 6 0.38 3.0e-12 4.8 -5.2 2.5e-07 0.02 1.00 0.00 FALSE
14 GTEx Brain Cortex AC135178.1 0.26 0.19 lasso 2 0.21 1.5e-06 6.7 -6.7 2.2e-11 -0.03 0.28 0.05 FALSE
15 GTEx Cells Transformed fibroblasts CHRNB1 0.28 0.11 enet 25 0.18 2.9e-13 -1.9 -5.2 1.8e-07 -0.04 1.00 0.00 FALSE
16 GTEx Cells Transformed fibroblasts PFAS 0.13 0.05 lasso 6 0.07 4.1e-06 8.9 8.2 3.1e-16 -0.03 0.47 0.50 FALSE
17 GTEx Cells Transformed fibroblasts AC135178.1 0.31 0.14 lasso 5 0.13 8.4e-10 -6.7 -6.9 4.1e-12 -0.02 1.00 0.00 FALSE
18 GTEx Colon Transverse LSMD1 0.28 0.12 lasso 5 0.19 3.3e-09 7.4 8.1 3.9e-16 0.43 0.98 0.00 FALSE
19 GTEx Colon Transverse AC135178.1 0.18 0.03 lasso 7 0.03 1.1e-02 -6.6 -6.2 4.5e-10 -0.02 0.35 0.03 FALSE
20 GTEx Colon Transverse RP11-849F2.8 0.18 0.12 enet 25 0.10 2.5e-05 6.1 -6.1 1.0e-09 -0.03 0.91 0.01 FALSE
21 GTEx Esophagus Mucosa KCNAB3 0.20 0.12 lasso 9 0.08 3.1e-06 5.6 -5.6 2.2e-08 -0.72 0.96 0.03 FALSE
22 GTEx Esophagus Muscularis CNTROB 0.10 0.04 lasso 4 0.02 1.6e-02 5.7 -5.8 5.4e-09 -0.73 0.08 0.72 FALSE
23 GTEx Esophagus Muscularis ZBTB4 0.13 0.06 lasso 2 0.05 6.3e-04 -5.1 -6.1 1.1e-09 -0.13 0.36 0.03 FALSE
24 GTEx Lung CNTROB 0.15 0.06 enet 28 0.07 9.5e-06 5.9 -7.2 7.3e-13 -0.45 0.64 0.03 TRUE
25 GTEx Lung KCNAB3 0.14 0.05 lasso 4 0.04 2.9e-04 5.5 -5.6 2.1e-08 -0.72 0.99 0.00 FALSE
26 GTEx Muscle Skeletal AC135178.1 0.20 0.08 lasso 5 0.14 2.8e-13 4.7 -6.9 5.5e-12 -0.03 1.00 0.00 FALSE
27 GTEx Nerve Tibial CNTROB 0.17 0.09 enet 14 0.13 9.7e-10 6.3 -7.1 1.6e-12 -0.75 0.95 0.05 FALSE
28 GTEx Nerve Tibial KCNAB3 0.17 0.11 lasso 8 0.09 3.1e-07 5.7 -6.3 2.9e-10 -0.71 1.00 0.00 FALSE
29 GTEx Nerve Tibial AC135178.1 0.12 0.06 lasso 2 0.05 1.6e-04 -6.5 -6.6 4.5e-11 0.00 0.98 0.00 FALSE
30 GTEx Pancreas CNTROB 0.14 0.06 lasso 8 0.03 1.5e-02 6.7 -7.5 4.6e-14 -0.76 0.23 0.42 FALSE
31 GTEx Pancreas TRAPPC1 0.17 0.00 lasso 6 0.01 1.5e-01 -5.1 -8.4 3.2e-17 -0.30 0.08 0.35 FALSE
32 GTEx Pancreas KCNAB3 0.16 0.07 enet 14 0.12 1.0e-05 5.5 -7.8 5.6e-15 -0.70 0.83 0.04 FALSE
33 GTEx Prostate AC113189.5 0.43 0.02 lasso 5 0.01 2.0e-01 -4.2 5.8 5.9e-09 0.21 0.06 0.06 FALSE
34 GTEx Skin Not Sun Exposed Suprapubic CNTROB 0.11 0.09 lasso 3 0.09 1.2e-05 5.7 -5.7 9.7e-09 -0.69 0.82 0.03 FALSE
35 GTEx Skin Sun Exposed Lower leg AC135178.1 0.23 0.14 enet 10 0.15 3.4e-12 -6.5 -7.5 6.2e-14 -0.01 1.00 0.00 FALSE
36 GTEx Skin Sun Exposed Lower leg RP11-849F2.9 0.13 0.00 enet 34 0.02 1.1e-02 8.9 7.9 2.4e-15 0.29 0.11 0.32 FALSE
37 GTEx Spleen CNTROB 0.22 0.04 enet 19 0.03 7.4e-02 5.7 -7.2 8.3e-13 -0.57 0.14 0.26 FALSE
38 GTEx Testis CYB5D1 0.37 0.12 lasso 4 0.12 4.2e-06 6.7 5.6 2.1e-08 0.45 0.94 0.04 FALSE
39 GTEx Testis RP11-849F2.5 0.45 0.40 lasso 5 0.40 2.6e-19 -6.5 -6.7 1.6e-11 -0.01 1.00 0.00 FALSE
40 GTEx Thyroid CNTROB 0.12 0.08 lasso 2 0.06 1.9e-05 5.7 -5.2 1.9e-07 -0.69 0.96 0.01 FALSE
41 GTEx Thyroid KCNAB3 0.15 0.14 enet 16 0.12 1.6e-09 5.5 -5.3 9.0e-08 -0.73 1.00 0.00 FALSE
42 METSIM Adipose AC135178.1 0.17 0.12 enet 19 0.14 7.4e-20 -6.5 -7.2 6.6e-13 0.05 1.00 0.00 FALSE
43 METSIM Adipose ARHGEF15 0.06 0.00 blup 449 0.02 3.1e-04 -2.6 6.3 3.5e-10 0.23 0.07 0.17 FALSE
44 METSIM Adipose KRBA2 0.17 0.13 lasso 5 0.15 7.1e-22 4.8 -6.3 2.2e-10 -0.03 1.00 0.00 FALSE
45 METSIM Adipose TMEM88 0.09 0.02 bslmm 500 0.03 4.6e-05 3.7 6.1 9.1e-10 0.25 0.62 0.04 FALSE
46 ROSMAP Brain Pre-frontal Cortex KDM6B 0.07 0.05 lasso 4 0.04 2.7e-06 7.4 -8.6 9.3e-18 -0.49 0.78 0.19 FALSE
47 ROSMAP Brain Pre-frontal Cortex GUCY2D 0.05 0.09 lasso 1 0.08 7.4e-11 6.0 -6.0 2.6e-09 -0.55 1.00 0.00 FALSE
48 ROSMAP Brain Pre-frontal Cortex CNTROB 0.09 0.11 enet 27 0.09 5.2e-12 5.5 -5.2 2.1e-07 -0.65 1.00 0.00 FALSE
49 ROSMAP Brain Pre-frontal Cortex KCNAB3 0.07 0.08 enet 15 0.08 1.5e-10 5.6 -6.0 2.1e-09 -0.72 1.00 0.00 TRUE
50 ROSMAP Brain Pre-frontal Cortex PFAS 0.08 0.02 enet 10 0.03 4.4e-05 8.9 9.6 5.4e-22 0.05 0.31 0.66 TRUE
51 ROSMAP Brain Pre-frontal Cortex AC135178.1 0.26 0.27 lasso 3 0.28 2.1e-35 4.7 -5.4 7.4e-08 -0.03 1.00 0.00 FALSE
52 YFS Blood CNTROB 0.02 0.01 bslmm 487 0.01 5.6e-05 5.7 -5.3 1.0e-07 -0.66 0.80 0.13 FALSE
53 YFS Blood CYB5D1 0.28 0.19 bslmm 488 0.24 5.9e-79 6.7 -8.7 2.3e-18 -0.48 1.00 0.00 FALSE
54 YFS Blood KDM6B 0.07 0.04 enet 34 0.04 1.1e-13 7.4 -6.7 2.0e-11 -0.28 1.00 0.00 FALSE
55 YFS Blood MYH10 0.03 0.00 blup 508 0.01 1.1e-03 3.5 -5.5 2.9e-08 0.07 0.11 0.02 FALSE
56 The Cancer Genome Atlas Bladder Urothelial Carcinoma CYB5D1 0.04 0.03 blup 40 0.02 1.6e-02 7.4 -9.0 1.6e-19 -0.54 0.02 0.43 TRUE
57 The Cancer Genome Atlas Bladder Urothelial Carcinoma EFNB3 0.03 0.00 blup 36 0.01 7.2e-02 4.1 -5.4 7.0e-08 -0.09 0.02 0.07 TRUE
58 The Cancer Genome Atlas Breast Invasive Carcinoma AURKB 0.02 0.01 blup 49 0.01 2.9e-03 1.4 5.7 1.4e-08 0.07 0.00 0.63 TRUE
59 The Cancer Genome Atlas Breast Invasive Carcinoma GUCY2D 0.05 0.02 blup 50 0.03 1.1e-06 6.3 -7.0 3.0e-12 -0.41 0.01 0.98 FALSE
60 The Cancer Genome Atlas Breast Invasive Carcinoma PFAS 0.02 0.01 lasso 3 0.01 9.7e-03 8.9 8.5 2.3e-17 0.04 0.00 0.99 FALSE
61 The Cancer Genome Atlas Breast Invasive Carcinoma RNF222 0.02 0.02 lasso 2 0.02 3.2e-04 -6.2 -5.7 1.3e-08 0.01 0.09 0.66 TRUE
62 The Cancer Genome Atlas Colon Adenocarcinoma CYB5D1 0.14 0.12 lasso 1 0.10 1.7e-06 7.4 -7.4 1.4e-13 -0.29 0.94 0.00 FALSE
63 The Cancer Genome Atlas Colon Adenocarcinoma VAMP2 0.06 0.00 blup 47 0.02 2.1e-02 5.9 7.3 3.6e-13 0.05 0.02 0.62 FALSE
64 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C17orf68 0.05 0.00 blup 59 0.03 3.3e-04 4.1 6.0 2.5e-09 0.03 0.01 0.93 TRUE
65 The Cancer Genome Atlas Brain Lower Grade Glioma C17orf59 0.04 0.01 blup 50 0.03 6.5e-04 2.1 5.4 5.8e-08 0.05 0.05 0.86 FALSE
66 The Cancer Genome Atlas Brain Lower Grade Glioma KCNAB3 0.02 0.01 blup 53 0.02 5.4e-03 5.7 -7.6 3.4e-14 -0.82 0.03 0.90 FALSE
67 The Cancer Genome Atlas Brain Lower Grade Glioma KRBA2 0.04 0.00 blup 48 0.02 5.4e-03 4.8 -5.6 2.3e-08 -0.04 0.02 0.05 FALSE
68 The Cancer Genome Atlas Brain Lower Grade Glioma LOC100128288 0.05 0.05 enet 4 0.05 6.1e-06 4.8 -6.2 5.9e-10 -0.02 0.89 0.01 FALSE
69 The Cancer Genome Atlas Brain Lower Grade Glioma PFAS 0.03 0.02 blup 54 0.03 1.3e-04 6.6 7.7 1.4e-14 0.00 0.07 0.87 FALSE
70 The Cancer Genome Atlas Brain Lower Grade Glioma VAMP2 0.03 0.02 blup 47 0.01 2.9e-02 4.4 -5.8 5.9e-09 -0.05 0.13 0.21 FALSE
71 The Cancer Genome Atlas Lung Adenocarcinoma CYB5D1 0.05 0.03 blup 40 0.03 1.9e-04 7.4 -7.9 2.9e-15 -0.36 0.06 0.06 FALSE
72 The Cancer Genome Atlas Lung Adenocarcinoma GUCY2D 0.02 0.00 blup 47 0.01 1.8e-02 6.3 -6.7 1.9e-11 -0.65 0.00 0.96 FALSE
73 The Cancer Genome Atlas Lung Adenocarcinoma PFAS 0.04 0.03 blup 54 0.04 4.0e-05 6.6 8.4 6.5e-17 0.00 0.10 0.80 FALSE
74 The Cancer Genome Atlas Lung Adenocarcinoma SLC25A35 0.02 0.01 blup 50 0.01 6.7e-03 7.7 9.2 3.6e-20 -0.01 0.01 0.58 FALSE
75 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CHD3 0.03 0.00 blup 62 0.03 6.0e-04 6.6 6.0 1.6e-09 0.75 0.02 0.60 FALSE
76 The Cancer Genome Atlas Lung Squamous Cell Carcinoma LOC284023 0.09 0.01 blup 55 0.03 5.5e-04 6.9 7.1 1.2e-12 0.41 0.02 0.34 FALSE
77 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PFAS 0.02 0.01 blup 54 0.01 8.1e-03 8.9 9.0 3.1e-19 0.01 0.00 0.90 TRUE
78 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RANGRF 0.05 0.01 blup 46 0.02 4.0e-03 6.7 8.1 3.9e-16 0.03 0.10 0.04 FALSE
79 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TNFSF12-TNFSF13 0.06 0.00 blup 58 0.01 3.4e-02 2.7 5.7 1.5e-08 -0.02 0.01 0.40 FALSE
80 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PFAS 0.04 0.04 blup 50 0.03 6.7e-03 6.5 8.3 9.5e-17 0.00 0.05 0.52 FALSE
81 The Cancer Genome Atlas Pancreatic Adenocarcinoma GUCY2D 0.14 0.04 lasso 2 0.04 9.5e-03 5.4 -5.8 6.9e-09 -0.57 0.02 0.21 FALSE
82 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LOC100128288 0.12 0.06 lasso 4 0.10 6.8e-05 4.8 -6.7 2.9e-11 -0.03 0.11 0.17 FALSE
83 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma VAMP2 0.16 0.02 enet 10 0.03 2.8e-02 5.1 -5.6 2.5e-08 -0.03 0.04 0.11 FALSE
84 The Cancer Genome Atlas Prostate Adenocarcinoma CYB5D1 0.07 0.02 enet 14 0.02 5.5e-03 7.4 -7.0 2.6e-12 -0.07 0.04 0.03 FALSE
85 The Cancer Genome Atlas Prostate Adenocarcinoma GUCY2D 0.06 0.08 enet 5 0.09 9.5e-10 5.5 -6.2 6.3e-10 -0.73 0.01 0.99 FALSE
86 The Cancer Genome Atlas Prostate Adenocarcinoma KCNAB3 0.03 0.01 blup 52 0.03 7.0e-04 5.6 -6.1 8.4e-10 -0.66 0.13 0.25 FALSE
87 The Cancer Genome Atlas Prostate Adenocarcinoma PFAS 0.05 0.06 enet 6 0.03 1.5e-04 8.0 8.3 1.5e-16 0.02 0.53 0.34 FALSE
88 The Cancer Genome Atlas Prostate Adenocarcinoma SHBG 0.04 0.01 blup 60 0.03 5.4e-04 6.3 5.7 1.6e-08 0.12 0.01 0.46 FALSE
89 The Cancer Genome Atlas Prostate Adenocarcinoma SLC25A35 0.09 0.06 enet 12 0.11 3.9e-11 6.4 5.6 1.7e-08 -0.01 0.01 0.99 FALSE
90 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM88 0.06 0.00 enet 10 0.01 6.5e-02 7.5 7.0 3.1e-12 0.22 0.01 0.08 FALSE
91 The Cancer Genome Atlas Prostate Adenocarcinoma VAMP2 0.06 0.05 lasso 1 0.04 3.1e-05 5.5 -5.5 3.6e-08 -0.05 0.51 0.02 FALSE
92 The Cancer Genome Atlas Soft Tissue Sarcoma PFAS 0.10 0.05 blup 54 0.03 6.2e-03 6.5 5.6 2.4e-08 -0.04 0.05 0.33 FALSE
93 The Cancer Genome Atlas Stomach Adenocarcinoma GUCY2D 0.06 0.04 blup 50 0.04 8.9e-04 5.6 -6.4 1.4e-10 -0.65 0.02 0.92 FALSE
94 The Cancer Genome Atlas Thyroid Carcinoma CNTROB 0.14 0.07 blup 50 0.10 4.8e-10 6.5 -7.4 9.8e-14 -0.62 0.97 0.03 FALSE
95 The Cancer Genome Atlas Thyroid Carcinoma FXR2 0.04 0.03 lasso 1 0.02 1.8e-03 -5.7 -5.7 1.2e-08 -0.01 0.01 0.90 FALSE
96 The Cancer Genome Atlas Thyroid Carcinoma GUCY2D 0.09 0.13 enet 8 0.13 3.0e-12 6.6 -7.1 1.3e-12 -0.66 0.00 1.00 FALSE
97 The Cancer Genome Atlas Thyroid Carcinoma KCNAB3 0.03 0.01 blup 52 0.02 4.7e-03 -6.1 -7.5 5.2e-14 -0.83 0.02 0.74 FALSE
98 The Cancer Genome Atlas Thyroid Carcinoma PFAS 0.07 0.06 enet 11 0.07 1.1e-07 7.5 8.6 6.8e-18 0.04 0.28 0.71 FALSE
99 The Cancer Genome Atlas Thyroid Carcinoma SENP3 0.07 0.04 enet 9 0.03 2.7e-04 -5.7 -7.4 1.3e-13 0.00 0.00 0.99 TRUE
100 The Cancer Genome Atlas Thyroid Carcinoma TRAPPC1 0.12 0.02 lasso 4 0.05 2.6e-05 3.7 -6.4 1.5e-10 -0.45 0.18 0.38 FALSE
101 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma GUCY2D 0.17 0.13 enet 7 0.18 9.7e-06 5.5 -6.1 9.3e-10 -0.68 0.02 0.97 FALSE