Hub : Traits :

Alcohol drinker status: Never

1 significantly associated models · 1 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 5 139905844 141305283 1 1 1.5e-07 1.2e-05 0.039 78 PCDHB14

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder (2018) 2.63 1 0 0 0 1 PCDHB14
Bipolar Disorder or Schizophrenia 2.21 1 0 0 0 1 PCDHB14
Bipolar Disorder (2011) 4.09 1 0 0 0 1 PCDHB14
Blood White Count 0.64 1 0 0 0 1 PCDHB14
Waist Hip Ratio (WHR) 1.50 1 0 0 0 1 PCDHB14
Pack years adult smoking proportion 3.79 1 0 0 0 1 PCDHB14
Trunk fat percentage 2.56 1 0 0 0 1 PCDHB14
Body mass index (BMI) 1.16 1 0 0 0 1 PCDHB14
Trunk fat mass 2.07 1 0 0 0 1 PCDHB14
Weight 0.85 1 0 0 0 1 PCDHB14
Arm fat percentage (right) 1.90 1 0 0 0 1 PCDHB14
Hip circumference 1.21 1 0 0 0 1 PCDHB14
Arm fat mass (right) 1.45 1 0 0 0 1 PCDHB14
Body fat percentage 2.30 1 0 0 0 1 PCDHB14
Emphysema/chronic bronchitis 7.46 1 0 0 0 1 PCDHB14
Whole body fat mass 1.72 1 0 0 0 1 PCDHB14
Supplements: Vitamin C 3.75 1 0 0 0 1 PCDHB14
Arm fat percentage (left) 1.99 1 0 0 0 1 PCDHB14
Back pain experienced in last month 3.61 1 0 0 0 1 PCDHB14
Arm fat mass (left) 1.70 1 0 0 0 1 PCDHB14
Guilty feelings 2.93 1 0 0 0 1 PCDHB14
Hearing aid user 3.69 1 0 0 0 1 PCDHB14
Pain type(s) experienced in last month: Hip pain 5.00 1 0 0 0 1 PCDHB14
Leg fat percentage (left) 1.34 1 0 0 0 1 PCDHB14
Commuting to job workplace: Cycle 5.35 1 0 0 0 1 PCDHB14
Myopia 5.22 1 0 0 0 1 PCDHB14
Pain experienced in last month 6.67 1 0 0 0 1 PCDHB14
Pack years of smoking 3.54 1 0 0 0 1 PCDHB14
Leg fat mass (left) 1.18 1 0 0 0 1 PCDHB14

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 0 0.000 1.2
GTEx Adipose Visceral Omentum 0 0.000 1.2
GTEx Adrenal Gland 0 0.000 1.2
GTEx Artery Aorta 0 0.000 1.3
GTEx Artery Coronary 0 0.000 1.3
GTEx Artery Tibial 0 0.000 1.2
GTEx Brain Caudate basal ganglia 0 0.000 1.3
GTEx Brain Cerebellar Hemisphere 0 0.000 1.1
GTEx Brain Cerebellum 0 0.000 1.2
GTEx Brain Cortex 0 0.000 1.3
GTEx Brain Frontal Cortex BA9 0 0.000 1.2
GTEx Brain Hippocampus 0 0.000 1.3
GTEx Brain Hypothalamus 0 0.000 1.2
GTEx Brain Nucleus accumbens basal ganglia 0 0.000 1.3
GTEx Brain Putamen basal ganglia 0 0.000 1.2
GTEx Breast Mammary Tissue 0 0.000 1.3
GTEx Breast Mammary Tissue (Male) 0 0.000 1.2
GTEx Breast Mammary Tissue (Female) 0 0.000 1.2
GTEx Cells EBV-transformed lymphocytes 0 0.000 1.2
GTEx Cells Transformed fibroblasts 0 0.000 1.2
GTEx Colon Sigmoid 0 0.000 1.2
GTEx Colon Transverse 0 0.000 1.2
GTEx Esophagus Gastroesophageal Junction 0 0.000 1.3
GTEx Esophagus Mucosa 0 0.000 1.2
GTEx Esophagus Muscularis 0 0.000 1.2
GTEx Heart Atrial Appendage 0 0.000 1.2
GTEx Heart Left Ventricle 0 0.000 1.3
GTEx Liver 0 0.000 1.2
GTEx Lung 0 0.000 1.2
GTEx Muscle Skeletal 0 0.000 1.2
GTEx Nerve Tibial 0 0.000 1.2
GTEx Ovary 0 0.000 1.2
GTEx Pancreas 0 0.000 1.2
GTEx Pituitary 0 0.000 1.2
GTEx Prostate 0 0.000 1.2
GTEx Skin Not Sun Exposed Suprapubic 0 0.000 1.2
GTEx Skin Sun Exposed Lower leg 0 0.000 1.2
GTEx Small Intestine Terminal Ileum 0 0.000 1.3
GTEx Spleen 0 0.000 1.2
GTEx Stomach 0 0.000 1.3
GTEx Testis 1 0.032 1.2
GTEx Thyroid 0 0.000 1.2
GTEx Uterus 0 0.000 1.2
GTEx Vagina 0 0.000 1.3
GTEx Whole Blood 0 0.000 1.2
METSIM Adipose 0 0.000 1.1
NTR Blood 0 0.000 1.1
ROSMAP Brain Pre-frontal Cortex 0 0.000 1.1
YFS Blood 0 0.000 1.1
CommonMind Brain Pre-frontal Cortex 0 0.000 1.2
The Cancer Genome Atlas Bladder Urothelial Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Breast Invasive Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Colon Adenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Esophageal Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Glioblastoma Multiforme 0 0.000 1.2
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 0 0.000 1.3
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Brain Lower Grade Glioma 0 0.000 1.2
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 0 0.000 1.3
The Cancer Genome Atlas Lung Adenocarcinoma 0 0.000 1.1
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Pancreatic Adenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 0 0.000 1.2
The Cancer Genome Atlas Prostate Adenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Rectum Adenocarcinoma 0 0.000 1.1
The Cancer Genome Atlas Soft Tissue Sarcoma 0 0.000 1.2
The Cancer Genome Atlas Skin Cutaneous Melanoma 0 0.000 1.1
The Cancer Genome Atlas Stomach Adenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Testicular Germ Cell Tumors 0 0.000 1.2
The Cancer Genome Atlas Thyroid Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 0 0.000 1.1