Hub : Traits :

Alcohol drinker status: Never

1 significantly associated models · 1 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 5 139905844 141305283 1 1 1.5e-07 1.2e-05 0.039 78 PCDHB14

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder 3.98 1 0 0 0 1 PCDHB14
Blood White Count 0.64 1 0 0 0 1 PCDHB14
Waist Hip Ratio (WHR) 1.48 1 0 0 0 1 PCDHB14
Pack years adult smoking proportion 3.79 1 0 0 0 1 PCDHB14
Trunk fat percentage 2.49 1 0 0 0 1 PCDHB14
Body mass index (BMI) 1.13 1 0 0 0 1 PCDHB14
Trunk fat mass 2.01 1 0 0 0 1 PCDHB14
Weight 0.82 1 0 0 0 1 PCDHB14
Arm fat percentage (right) 1.85 1 0 0 0 1 PCDHB14
Hip circumference 1.17 1 0 0 0 1 PCDHB14
Arm fat mass (right) 1.41 1 0 0 0 1 PCDHB14
Body fat percentage 2.25 1 0 0 0 1 PCDHB14
Emphysema/chronic bronchitis 7.40 1 0 0 0 1 PCDHB14
Whole body fat mass 1.67 1 0 0 0 1 PCDHB14
Supplements: Vitamin C 3.74 1 0 0 0 1 PCDHB14
Arm fat percentage (left) 1.94 1 0 0 0 1 PCDHB14
Back pain experienced in last month 3.59 1 0 0 0 1 PCDHB14
Arm fat mass (left) 1.65 1 0 0 0 1 PCDHB14
Guilty feelings 2.90 1 0 0 0 1 PCDHB14
Hearing aid user 3.70 1 0 0 0 1 PCDHB14
Pain type(s) experienced in last month: Hip pain 4.98 1 0 0 0 1 PCDHB14
Leg fat percentage (left) 1.31 1 0 0 0 1 PCDHB14
Commuting to job workplace: Cycle 5.30 1 0 0 0 1 PCDHB14
Myopia 5.21 1 0 0 0 1 PCDHB14
Pain experienced in last month 6.59 1 0 0 0 1 PCDHB14
Pack years of smoking 3.53 1 0 0 0 1 PCDHB14
Leg fat mass (left) 1.15 1 0 0 0 1 PCDHB14

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 0 0.0000 1.24
GTEx Adipose Visceral Omentum 0 0.0000 1.25
GTEx Adrenal Gland 0 0.0000 1.21
GTEx Artery Aorta 0 0.0000 1.27
GTEx Artery Coronary 0 0.0000 1.29
GTEx Artery Tibial 0 0.0000 1.24
GTEx Brain Caudate basal ganglia 0 0.0000 1.26
GTEx Brain Cerebellar Hemisphere 0 0.0000 1.13
GTEx Brain Cerebellum 0 0.0000 1.23
GTEx Brain Cortex 0 0.0000 1.32
GTEx Brain Frontal Cortex BA9 0 0.0000 1.17
GTEx Brain Hippocampus 0 0.0000 1.28
GTEx Brain Hypothalamus 0 0.0000 1.20
GTEx Brain Nucleus accumbens basal ganglia 0 0.0000 1.28
GTEx Brain Putamen basal ganglia 0 0.0000 1.18
GTEx Breast Mammary Tissue 0 0.0000 1.28
GTEx Breast Mammary Tissue (Male) 0 0.0000 1.24
GTEx Breast Mammary Tissue (Female) 0 0.0000 1.18
GTEx Cells EBV-transformed lymphocytes 0 0.0000 1.21
GTEx Cells Transformed fibroblasts 0 0.0000 1.24
GTEx Colon Sigmoid 0 0.0000 1.21
GTEx Colon Transverse 0 0.0000 1.21
GTEx Esophagus Gastroesophageal Junction 0 0.0000 1.26
GTEx Esophagus Mucosa 0 0.0000 1.24
GTEx Esophagus Muscularis 0 0.0000 1.22
GTEx Heart Atrial Appendage 0 0.0000 1.24
GTEx Heart Left Ventricle 0 0.0000 1.28
GTEx Liver 0 0.0000 1.23
GTEx Lung 0 0.0000 1.25
GTEx Muscle Skeletal 0 0.0000 1.20
GTEx Nerve Tibial 0 0.0000 1.20
GTEx Ovary 0 0.0000 1.24
GTEx Pancreas 0 0.0000 1.23
GTEx Pituitary 0 0.0000 1.17
GTEx Prostate 0 0.0000 1.25
GTEx Skin Not Sun Exposed Suprapubic 0 0.0000 1.21
GTEx Skin Sun Exposed Lower leg 0 0.0000 1.22
GTEx Small Intestine Terminal Ileum 0 0.0000 1.28
GTEx Spleen 0 0.0000 1.23
GTEx Stomach 0 0.0000 1.30
GTEx Testis 1 0.0317 1.23
GTEx Thyroid 0 0.0000 1.20
GTEx Uterus 0 0.0000 1.22
GTEx Vagina 0 0.0000 1.28
GTEx Whole Blood 0 0.0000 1.16
METSIM Adipose 0 0.0000 1.14
NTR Blood 0 0.0000 1.12
ROSMAP Brain Pre-frontal Cortex 0 0.0000 1.14
YFS Blood 0 0.0000 1.12
CommonMind Brain Pre-frontal Cortex 0 0.0000 1.22
TCGA Breast Tumor 0 0.0000 1.14
TCGA Breast Normal 0 0.0000 1.16
TCGA Ovarian Tumor 0 0.0000 1.17
TCGA Prostate Tumor 0 0.0000 1.20