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chr19:9,637,688-13,742,702

Best TWAS P=1.03e-34 · Best GWAS P=7.61e-26 conditioned to 0.234

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	GTEx	Esophagus Mucosa	ILF3-AS1	0.11	0.00	lasso	4	0.00	2.5e-01	10.5	-12.3	1.0e-34	-0.77	0.01	0.91	TRUE
2	CommonMind	Brain Pre-frontal Cortex	ZNF788	0.08	0.05	lasso	6	0.04	5.9e-06	9.4	9.3	9.8e-21	-0.09	0.01	0.99	TRUE
47	The Cancer Genome Atlas	Breast Invasive Carcinoma	S1PR2	0.02	0.00	blup	32	0.01	1.5e-02	-7.7	8.5	2.7e-17	0.04	0.01	0.03	TRUE
50	The Cancer Genome Atlas	Brain Lower Grade Glioma	KANK2	0.28	0.26	lasso	3	0.26	4.6e-29	-8.6	-8.4	3.2e-17	0.00	0.05	0.95	TRUE
35	GTEx	Testis	JUNB	0.21	-0.01	lasso	7	0.00	1.9e-01	6.5	7.5	7.9e-14	-0.07	0.03	0.34	TRUE
14	GTEx	Cells EBV-transformed lymphocytes	CTD-3105H18.4	0.20	0.20	lasso	3	0.16	6.9e-06	6.5	-7.3	3.0e-13	0.06	0.31	0.31	TRUE
28	GTEx	Muscle Skeletal	CTD-3105H18.14	0.15	0.09	lasso	8	0.07	1.4e-07	6.7	-6.8	1.1e-11	0.04	1.00	0.00	TRUE
39	GTEx	Vagina	CTD-2369P2.2	0.50	-0.01	lasso	9	0.01	2.0e-01	8.8	6.7	1.6e-11	0.01	0.22	0.11	TRUE
23	GTEx	Lung	GCDH	0.25	0.14	enet	16	0.15	1.7e-11	4.8	5.5	4.4e-08	-0.01	1.00	0.00	TRUE
59	The Cancer Genome Atlas	Thyroid Carcinoma	S1PR5	0.06	0.02	blup	41	0.03	8.3e-04	-1.1	5.3	9.7e-08	0.20	0.01	0.70	TRUE
56	The Cancer Genome Atlas	Prostate Adenocarcinoma	SPC24	0.06	0.00	enet	15	0.01	1.4e-02	3.8	-5.3	1.3e-07	-0.21	0.01	0.10	TRUE
52	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF799	0.03	0.02	blup	35	0.02	6.2e-03	6.7	-5.1	2.8e-07	0.06	0.00	0.89	TRUE
30	GTEx	Nerve Tibial	ILF3-AS1	0.14	0.04	lasso	3	0.08	3.8e-06	10.4	-11.8	6.8e-32	-0.77	0.01	0.98	FALSE
45	ROSMAP	Brain Pre-frontal Cortex	ILF3-AS1	0.15	0.04	bslmm	354	0.18	7.1e-22	-6.0	-11.4	6.4e-30	-0.61	0.05	0.95	FALSE
48	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC147727	0.13	0.02	blup	28	0.04	7.2e-05	10.4	-11.3	1.9e-29	-0.76	0.01	0.89	FALSE
51	The Cancer Genome Atlas	Brain Lower Grade Glioma	LOC147727	0.07	0.02	lasso	2	0.02	5.4e-03	10.5	-11.0	6.6e-28	-0.99	0.01	0.88	FALSE
26	GTEx	Muscle Skeletal	SLC44A2	0.19	0.18	lasso	5	0.19	5.1e-18	10.0	10.5	6.7e-26	0.79	0.45	0.55	FALSE
4	GTEx	Adipose Subcutaneous	ILF3-AS1	0.18	0.05	enet	27	0.12	1.2e-09	-6.0	-10.1	5.2e-24	-0.49	0.13	0.76	FALSE
58	The Cancer Genome Atlas	Thyroid Carcinoma	LOC147727	0.24	0.02	enet	18	0.07	6.1e-07	9.9	-10.0	1.5e-23	-0.35	0.01	0.22	FALSE
22	GTEx	Heart Left Ventricle	ILF3-AS1	0.16	0.06	lasso	9	0.04	3.1e-03	-7.2	-8.9	3.8e-19	-0.16	0.13	0.05	FALSE
24	GTEx	Lung	ILF3-AS1	0.11	0.10	lasso	4	0.09	1.8e-07	-7.2	-8.8	1.5e-18	-0.26	0.82	0.13	FALSE
34	GTEx	Skin Sun Exposed Lower leg	ILF3-AS1	0.14	0.08	enet	14	0.06	5.9e-06	-7.2	-8.6	5.5e-18	-0.35	0.92	0.06	FALSE
7	GTEx	Artery Aorta	ILF3-AS1	0.13	0.05	lasso	6	0.06	4.5e-04	-7.2	-8.2	3.3e-16	-0.16	0.37	0.28	FALSE
36	GTEx	Testis	ZNF442	0.16	0.06	enet	3	0.02	4.4e-02	6.7	7.8	4.8e-15	-0.06	0.06	0.48	FALSE
1	CommonMind	Brain Pre-frontal Cortex	S1PR2	0.07	0.02	bslmm	369	0.03	5.3e-05	-7.3	7.8	4.9e-15	0.31	0.32	0.14	FALSE
6	GTEx	Adipose Visceral Omentum	S1PR2	0.23	0.01	lasso	5	0.01	1.1e-01	-6.0	7.8	6.2e-15	0.10	0.06	0.24	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	CTD-3105H18.14	0.22	0.20	lasso	3	0.18	1.8e-06	6.5	-7.5	7.6e-14	0.06	0.34	0.24	FALSE
53	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SLC44A2	0.09	-0.01	blup	59	0.03	1.1e-02	9.9	-7.3	2.8e-13	-0.55	0.01	0.14	FALSE
18	GTEx	Colon Transverse	ILF3-AS1	0.17	0.11	lasso	4	0.10	2.1e-05	-6.1	-7.2	4.0e-13	-0.14	0.20	0.12	FALSE
31	GTEx	Skin Not Sun Exposed Suprapubic	CTD-3105H18.14	0.11	0.06	enet	10	0.06	3.8e-04	6.7	-7.1	1.6e-12	0.06	0.61	0.18	FALSE
19	GTEx	Esophagus Mucosa	SLC44A2	0.13	0.00	lasso	6	0.02	1.4e-02	4.5	-7.0	2.7e-12	-0.46	0.06	0.65	FALSE
42	NTR	Blood	SMARCA4	0.07	0.06	lasso	11	0.06	9.0e-18	6.4	-7.0	2.7e-12	-0.43	1.00	0.00	FALSE
16	GTEx	Cells Transformed fibroblasts	CTD-3105H18.4	0.16	0.14	enet	4	0.13	6.0e-10	6.7	-6.8	8.4e-12	0.05	1.00	0.00	FALSE
17	GTEx	Cells Transformed fibroblasts	CTD-3105H18.14	0.17	0.12	enet	5	0.12	1.3e-09	6.7	-6.8	1.1e-11	0.05	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	CTD-2369P2.2	0.20	0.00	lasso	4	0.00	3.2e-01	-6.9	6.8	1.4e-11	0.01	0.04	0.18	FALSE
44	ROSMAP	Brain Pre-frontal Cortex	ZNF799	0.04	0.04	lasso	1	0.02	7.6e-04	6.7	-6.7	1.9e-11	0.05	0.58	0.02	FALSE
27	GTEx	Muscle Skeletal	CTD-3105H18.4	0.13	0.07	lasso	6	0.05	1.5e-05	6.7	-6.6	3.9e-11	0.04	0.98	0.00	FALSE
41	GTEx	Whole Blood	SLC44A2	0.11	0.01	enet	30	0.02	5.2e-03	9.9	-6.6	4.7e-11	-0.60	0.02	0.90	FALSE
49	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF844	0.02	0.01	blup	27	0.01	9.2e-03	7.2	-6.5	1.1e-10	0.10	0.02	0.22	FALSE
60	The Cancer Genome Atlas	Thyroid Carcinoma	SLC44A2	0.32	0.22	enet	14	0.25	3.8e-24	8.0	6.4	1.3e-10	0.85	1.00	0.00	FALSE
21	GTEx	Esophagus Muscularis	CTD-3105H18.4	0.13	0.00	enet	5	0.02	3.4e-02	6.7	-6.3	2.9e-10	0.06	0.06	0.09	FALSE
38	GTEx	Testis	CTD-3105H18.14	0.27	0.16	lasso	5	0.13	1.7e-06	6.7	-6.3	3.3e-10	0.04	0.94	0.01	FALSE
11	GTEx	Breast Mammary Tissue (Female)	KRI1	0.17	0.03	lasso	3	0.03	3.5e-02	-5.8	-6.3	3.5e-10	-0.36	0.04	0.05	FALSE
29	GTEx	Nerve Tibial	CTD-3105H18.4	0.16	0.03	lasso	5	0.02	1.7e-02	6.7	-6.3	3.7e-10	0.06	0.29	0.03	FALSE
55	The Cancer Genome Atlas	Prostate Adenocarcinoma	KANK2	0.09	0.04	blup	76	0.06	9.5e-07	-8.4	-6.2	7.0e-10	0.01	0.01	0.98	FALSE
37	GTEx	Testis	CTD-3105H18.4	0.28	0.16	lasso	3	0.13	2.0e-06	6.7	-6.1	9.3e-10	0.04	0.94	0.02	FALSE
43	ROSMAP	Brain Pre-frontal Cortex	AP1M2	0.09	0.01	lasso	5	0.03	3.3e-05	4.5	6.1	1.2e-09	0.37	0.13	0.20	FALSE
3	GTEx	Adipose Subcutaneous	EPOR	0.11	0.04	lasso	7	0.04	3.8e-04	6.0	6.0	1.9e-09	0.39	0.83	0.01	FALSE
46	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC147727	0.19	0.01	enet	16	0.05	3.0e-10	10.4	-5.9	3.7e-09	-0.47	0.00	0.54	FALSE
32	GTEx	Skin Sun Exposed Lower leg	SMARCA4	0.15	0.10	enet	25	0.15	1.4e-12	5.5	-5.8	7.3e-09	-0.61	1.00	0.00	FALSE
12	GTEx	Breast Mammary Tissue (Female)	ZNF443	0.05	-0.01	lasso	4	0.00	3.4e-01	6.7	5.7	1.4e-08	-0.05	0.03	0.06	FALSE
33	GTEx	Skin Sun Exposed Lower leg	YIPF2	0.05	0.05	lasso	2	0.04	1.6e-04	5.6	-5.5	3.0e-08	-0.45	0.73	0.02	FALSE
25	GTEx	Muscle Skeletal	GCDH	0.13	0.00	enet	11	0.00	4.6e-01	1.5	5.4	6.8e-08	-0.03	0.15	0.03	FALSE
40	GTEx	Whole Blood	GCDH	0.10	0.03	lasso	4	0.03	1.4e-03	-4.8	5.3	1.1e-07	0.01	0.36	0.03	FALSE
54	The Cancer Genome Atlas	Lung Adenocarcinoma	KRI1	0.05	0.04	blup	51	0.03	7.3e-05	4.7	5.3	1.1e-07	0.41	0.25	0.61	FALSE
8	GTEx	Brain Cerebellum	GCDH	0.48	0.48	lasso	6	0.49	1.5e-16	-5.0	5.3	1.3e-07	0.02	1.00	0.00	FALSE
9	GTEx	Brain Cerebellum	AD000092.3	0.40	0.15	lasso	3	0.19	2.2e-06	-4.8	5.3	1.3e-07	0.02	0.70	0.02	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	FARSA	0.26	0.24	lasso	5	0.18	2.3e-06	4.8	5.3	1.4e-07	0.03	0.06	0.92	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	C19orf52	0.05	0.06	lasso	4	0.06	2.5e-06	4.7	-5.3	1.4e-07	-0.42	0.02	0.98	FALSE
10	GTEx	Brain Cortex	GCDH	0.33	0.23	lasso	4	0.26	7.7e-08	4.6	5.1	2.9e-07	0.02	0.91	0.00	FALSE