TWAS hub - ZNF799

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.0363	0.0208	0.0210	0.038	0.012	0.013	0.012	0.021	0.00001	0.0110	0.0073	0.0087	0.00076
2	TCGA	Brain Lower Grade Glioma	0.0310	0.0182	0.0042	0.025	0.015	-0.002	NA	0.008	0.00068	0.0062	0.9500	NA	0.03900

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Number of incorrect matches in round	11.6	19.3	21.8	-4.1	-4.7
Osteoporosis (self-reported)	7.4	9.1	9.4	3.1	3.0
Eye problems/disorders: None of the above	5.3	6.2	6.8	-2.6	-2.4
Type 2 Diabetes (T2D) (2018)	4.4	8.3	9.7	-3.1	-2.6
Leg pain on walking	4.2	5.3	5.6	2.2	2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.1	8.7	11.2	3.3	2.5
Diabetes (mother)	4.0	5.1	5.6	-2.4	-2.1
Knee pain experienced in last month	3.9	6.1	7.1	2.3	2.7
Family relationship satisfaction	3.7	4.6	5.6	2.4	1.9
Standing height	3.6	35.7	45.0	-6.7	-5.1
Diabetes (self-reported)	3.5	5.4	6.5	-2.5	-2.1
Type 2 Diabetes (T2D) (2012)	3.2	3.7	4.4	-1.8	-2.1
Diabetes diagnosed by doctor	3.2	5.2	5.5	-2.3	-2.2
Pain experienced in last month	3.2	5.4	7.6	-2.8	-1.8
Intelligence (Savage-Jansen 2018)	3.1	9.5	16.1	1.7	4.0
Hearing difficulty/problems: Yes	3.1	4.7	6.6	2.6	1.6
Ever had stillbirth, spontaneous miscarriage or termination	3.0	3.2	3.2	1.8	1.8
Breast cancer (self-reported)	2.9	3.5	5.2	1.3	2.3
Verbal and Numeric Reasoning (VNR)	2.7	6.4	6.9	2.4	2.6
Medication: Amlodipine	2.6	3.7	5.1	-2.3	-1.5
Diastolic blood pressure, automated reading	2.5	7.9	11.5	2.1	3.4
Bilateral oophorectomy (both ovaries removed)	2.4	2.7	3.3	-1.8	-1.5
Medication: Blood pressure	2.4	4.6	5.9	1.8	2.4
Medication: Seretide 50 evohaler	2.3	2.7	4.2	-1.0	-2.1
Medication for cholesterol	2.3	3.5	4.5	-1.6	-2.1
Osteoarthritis (self-reported)	2.2	2.9	4.0	1.3	2.0
Lung FVC	2.0	10.1	10.6	3.1	3.3
Hand grip strength (left)	2.0	5.3	6.7	-2.0	-2.6
Sitting height	2.0	14.2	18.8	-4.3	-3.1
Hair/balding pattern: Pattern 2	2.0	2.5	3.4	-1.3	-1.9
Risk taking	2.0	2.9	4.3	2.1	1.3
Pack years of smoking	2.0	2.9	3.0	-1.7	-1.7
Alzheimer’s Disease (in mother)	1.8	2.1	2.8	-1.2	-1.7
Pack years adult smoking proportion	1.8	2.7	3.0	-1.6	-1.7
Health satisfaction	1.8	2.3	2.4	1.6	1.5
Loneliness, isolation	1.8	2.5	2.9	1.4	1.7
Average weekly beer plus cider intake	1.8	2.6	3.5	1.9	1.3
Height	1.7	32.2	47.1	-6.9	-4.2
Ever had hysterectomy (womb removed)	1.7	2.0	2.8	-1.7	-1.1
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	2.4	1.3	1.5
Financial difficulties in last 2 years	1.7	2.3	4.1	2.0	0.7
High blood pressure (siblings)	1.7	2.5	4.1	1.0	2.0
Breast Cancer	1.6	3.9	5.3	-1.6	-2.3
Chest pain or discomfort	1.6	2.3	2.5	1.5	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	1.9	1.4	1.4
Eye problems/disorders: Glaucoma	1.6	1.9	2.2	1.5	1.3
Medication: Bendroflumethiazide	1.6	2.4	3.5	1.1	1.9
Reaction Time	1.5	2.8	3.6	-1.4	-1.9
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	2.4	1.5	1.6
Lupus	1.4	2.2	2.6	1.3	1.6
Age when periods started (menarche)	1.4	3.4	4.4	-2.1	-1.6
Multivitamins +/- minerals	1.4	1.8	2.0	1.2	1.4
Alzheimer’s Disease (including proxy)	1.3	1.9	2.1	-1.5	-1.3
Average weekly spirits intake	1.3	1.6	1.8	1.2	1.4
Qualifications: CSEs or equivalent	1.3	1.7	2.3	1.0	1.5
Ever unenthusiastic/disinterested for a whole week	1.3	1.5	1.9	-1.1	-1.4
Bipolar Disorder (2018)	1.2	1.8	3.0	-0.8	-1.7
Mean Putamen Volume	1.2	1.4	2.0	-0.9	-1.4
Stomach or abdominal pain in last month	1.2	1.5	3.1	1.8	-0.0
Fluid intelligence score	1.2	2.4	2.6	1.5	1.6
Headache pain in last month	1.2	2.0	3.0	1.7	1.0
Back pain experienced in last month	1.2	1.7	2.2	-1.1	-1.5
Medication: Metformin	1.1	1.6	2.0	-1.0	-1.4
High blood pressure	1.1	3.0	5.8	0.5	2.4
Age at first live birth	1.1	2.0	2.1	-1.4	-1.4
Shortness of breath walking on level ground	1.1	1.3	2.1	0.7	1.4
Alcohol drinker status: Previous	1.1	1.2	1.3	-1.2	-1.1
Ulcerative Colitis (UC)	1.0	1.8	1.9	-1.3	-1.4
Primary Biliary Cirrhosis	1.0	1.5	1.5	-1.2	-1.2
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	1.4	-1.2	-1.0
Medication: Co-codamol	1.0	1.2	1.4	1.0	1.2
Severe depression (siblings)	1.0	1.1	1.2	1.1	1.0
Impedance of leg (right)	1.0	4.7	5.2	-2.3	-2.0
Hand grip strength (right)	1.0	2.8	4.4	-1.1	-2.1
Serious illness, injury or assault to yourself	1.0	1.2	1.3	1.1	1.1
Supplements: Glucosamine	1.0	1.3	2.1	1.5	0.7
Trunk fat-free mass	1.0	6.0	8.9	-3.0	-1.8
Gout (self-reported)	1.0	1.4	2.0	0.9	1.4
Hypertension (Self-reported)	1.0	2.7	5.2	0.3	2.3
Smoking status: Previous	1.0	1.4	2.8	-1.7	-0.2
Myopia	1.0	1.5	1.8	-1.1	-1.4
Vascular/heart problems diagnosed by doctor	1.0	2.7	5.1	-0.5	-2.3
HDL Cholesterol	0.9	1.5	1.8	-1.0	-1.4
Neuroticism (2016)	0.9	1.3	1.6	-1.0	-1.3
Heart attack	0.9	1.2	2.4	0.1	1.5
Medication: Cholesterol lowering	0.9	1.5	1.6	-1.3	-1.2
Lung cancer (father)	0.9	1.0	1.0	-1.0	-1.0
Trunk predicted mass	0.9	5.3	8.0	-2.8	-1.6
Peak expiratory flow (PEF)	0.9	2.1	2.5	1.3	1.6
Glaucoma (self-reported)	0.9	1.1	1.3	1.1	0.9
Arm fat-free mass (right)	0.9	4.7	6.8	-2.6	-1.6
Arm predicted mass (right)	0.9	4.4	6.1	-2.5	-1.6
Had major operations	0.9	1.1	1.9	1.4	0.6
Body Mass Index (BMI) (2010)	0.8	1.2	1.2	1.1	1.1
HbA1C	0.8	0.9	1.6	-0.5	-1.3
Systolic blood pressure, automated reading	0.8	2.4	4.4	0.6	2.1
Diabetes (father)	0.8	1.0	1.3	-1.1	-0.9
Impedance of leg (left)	0.8	3.7	4.5	-2.1	-1.7
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	1.1	-1.0	-1.1
Prospective memory result	0.8	1.0	1.5	-1.2	-0.8
Medication: Paracetamol	0.8	1.4	2.0	1.4	0.9
Medication for pain relief, constipation, heartburn	0.8	1.3	1.7	-1.3	-1.0
Medication: Aspirin	0.8	1.1	1.6	0.8	1.2
Mother’s age at death	0.8	1.0	1.5	1.2	0.7
Lung FEV1/FVC ratio	0.7	3.7	5.2	1.5	2.3
Townsend deprivation index at recruitment	0.7	0.9	1.5	-0.6	-1.2
Maternal smoking around birth	0.7	1.0	1.8	-1.4	-0.3
Hayfever, allergic rhinitis or eczema	0.7	1.5	1.8	1.4	1.1
Pain all over the body in last month	0.7	0.8	0.8	0.8	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.1	0.7	1.0
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.6	1.3	0.2
Mean time to correctly identify matches	0.7	1.3	1.9	-0.9	-1.4
Tinnitus: Yes, now most or all of the time	0.7	0.9	1.7	1.3	0.1
Medication: Paracetamol	0.7	1.0	1.5	1.2	0.8
Ovarian Cancer	0.6	0.7	1.0	1.0	0.7
Blood Eosinophil Count	0.6	4.4	4.6	2.1	2.1
Waist Hip Ratio (WHR)	0.6	2.9	3.2	-1.8	-1.6
Systolic Blood Pressure	0.6	2.9	5.7	-0.2	2.4
Hypothyroidism (self reported)	0.6	1.3	1.9	0.8	1.4
High blood pressure (mother)	0.6	0.9	1.6	-0.5	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.3	0.9	1.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.0	-0.8	-1.0
Qualifications: College or University degree	0.6	1.9	2.7	1.1	1.6
Angina (self-reported)	0.6	0.9	1.1	-0.8	-1.0
Age at last live birth	0.6	0.9	1.4	-0.6	-1.2
Whole body fat-free mass	0.6	3.3	5.1	-2.2	-1.2
Whole body water mass	0.6	3.2	4.8	-2.2	-1.3
Average weekly champagne plus white wine intake	0.6	0.8	1.3	-0.6	-1.1
Commuting to job workplace: Public transport	0.6	0.7	1.2	-0.4	-1.1
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.5	0.2	1.2
Cholesterol lowering medication	0.6	0.9	1.4	0.6	1.2
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.5	-0.0	1.2
Arm predicted mass (left)	0.6	2.8	4.4	-2.1	-1.1
Sensitivity / hurt feelings	0.5	0.8	1.3	-1.1	-0.5
Average weekly fortified wine intake	0.5	0.6	0.8	-0.6	-0.9
Fed-up feelings	0.5	0.9	1.7	-1.3	-0.4
Relative age voice broke	0.5	0.7	1.5	-1.2	0.1
Body mass index (BMI)	0.5	2.3	2.5	1.6	1.5
Arm fat percentage (right)	0.5	1.9	2.2	1.5	1.3
Falls in the last year	0.5	0.6	0.8	0.9	0.7
Noisy workplace	0.5	0.6	0.7	0.8	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.1	1.1	0.2
Birth weight of first child	0.5	0.9	1.3	-1.1	-0.7
Heart disease (mother)	0.5	0.6	0.8	0.7	0.9
Pulse rate, automated reading	0.5	1.7	2.0	1.4	1.2
Comparative height size at age 10	0.5	2.6	2.6	-1.6	-1.6
Arm fat percentage (left)	0.5	2.1	2.6	1.6	1.2
Basal metabolic rate	0.5	2.8	4.1	-2.0	-1.2
Leg fat percentage (left)	0.5	1.7	2.3	1.0	1.5
Arm fat-free mass (left)	0.5	2.7	4.1	-2.0	-1.1
Alzheimer’s Disease (in father)	0.4	0.4	0.7	-0.2	0.9
Irritable Bowel Disease (IBD)	0.4	1.0	1.1	-0.9	-1.0
LDL Cholesterol	0.4	0.6	1.2	-0.1	-1.1
Blood Red Count	0.4	3.5	7.0	2.6	0.0
Cardiovascular Disease	0.4	1.2	2.2	-0.5	1.5
Angina	0.4	0.5	0.7	-0.5	-0.8
Medication for hormone replacement therapy	0.4	0.5	0.8	0.9	0.4
Medication: Levothyroxine sodium	0.4	0.7	1.4	0.3	1.2
Illnesses of siblings	0.4	0.6	0.6	-0.8	-0.7
Mouth/teeth dental problems: Dentures	0.4	0.8	1.3	-1.1	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	1.6	1.0	1.3
Ever highly irritable/argumentative for 2 days	0.4	0.4	0.5	-0.6	-0.7
Wheeze or whistling in the chest in last year	0.4	0.7	1.0	1.0	0.5
Neck or shoulder pain in last month	0.4	0.5	1.1	1.0	0.1
Supplements: Vitamin C	0.4	0.5	1.0	1.0	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.6	-0.6	-0.8
Handedness (chirality/laterality): Left-handed	0.4	0.4	0.7	0.8	0.4
Long-standing illness, disability or infirmity	0.4	0.5	0.6	0.7	0.8
Hearing aid user	0.4	0.4	0.5	0.7	0.6
Supplements: Fish oil (including cod liver oil)	0.4	0.5	0.8	-0.9	-0.4
Medication: Lisinopril	0.4	0.6	1.1	-0.2	1.1
Impedance of whole body	0.4	2.2	2.5	-1.4	-1.6
Schizophrenia (2018)	0.3	0.6	0.8	0.6	0.9
Age at First Birth	0.3	0.4	0.7	-0.4	-0.8
Fasting Glucose	0.3	0.3	0.6	-0.8	-0.3
Respiratory disease	0.3	0.8	1.5	-0.2	-1.2
Chronotype (morning person)	0.3	0.6	0.8	0.9	0.7
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.6	0.8	0.5
Leg fat-free mass (left)	0.3	1.4	1.9	-1.4	-1.0
Medication: Atenolol	0.3	0.3	0.6	0.2	0.8
Chronic bronchitis/emphysema (father)	0.3	0.4	0.4	0.6	0.6
Leg predicted mass (left)	0.3	1.5	2.0	-1.4	-1.0
Hearing difficulty/problems with background noise	0.3	0.4	0.8	0.9	0.2
Had menopause	0.3	0.4	0.7	0.4	0.8
Qualifications: None of the above	0.3	0.6	0.7	-0.7	-0.8
Allergy	0.3	0.7	0.9	-0.9	-0.8
Father’s age at death	0.3	0.4	0.7	-0.5	-0.8
Happiness	0.3	0.3	0.4	0.5	0.7
Illnesses of mother	0.3	0.3	0.6	0.2	-0.8
Impedance of arm (left)	0.3	1.3	1.8	-0.8	-1.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.9	1.0	0.2
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.5	-0.5	-0.7
Birth weight	0.3	0.7	1.4	-1.2	-0.2
Leg fat percentage (right)	0.3	1.2	1.4	1.0	1.2
Number of children fathered	0.3	0.3	0.4	-0.7	-0.4
Medication: Blood pressure	0.3	0.5	0.9	-1.0	0.3
Alcohol intake frequency.	0.3	0.7	1.3	0.2	1.1
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.7	-0.8	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	1.3	-1.1	-0.4
Friendships satisfaction	0.3	0.3	0.7	0.8	-0.1
Commuting to job workplace: Walk	0.3	0.3	0.6	-0.2	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.9	0.3	1.0
Medication: Aspirin	0.3	0.4	0.6	0.4	0.8
Illnesses of father: High blood pressure	0.3	0.3	0.5	-0.7	-0.3
Irritability	0.3	0.4	0.7	0.4	0.9
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.6	-0.1	0.8
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.6	-0.8	0.2
Crohns Disease (2017)	0.2	0.4	0.4	-0.7	-0.6
Ulcerative Colitis	0.2	0.2	0.5	-0.2	-0.7
BMI	0.2	0.9	1.2	0.7	1.1
Number of treatments/medications taken	0.2	0.4	0.8	0.0	0.9
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.3	-0.6	-0.6
Vitamin and mineral supplements	0.2	0.2	0.3	-0.6	-0.3
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.2	0.4	0.4
Past tobacco smoking	0.2	0.4	0.7	0.8	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	0.8	0.9	-0.3
Medication: Ramipril	0.2	0.2	0.3	-0.4	0.5
Weight	0.2	1.2	1.8	-1.3	-0.7
Hip circumference	0.2	0.7	1.3	0.0	1.1
Worrier / anxious feelings	0.2	0.3	0.5	-0.3	-0.7
Number of live births	0.2	0.3	0.3	0.5	0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	0.8	0.7	0.9
Medication: Lansoprazole	0.2	0.2	0.2	-0.5	-0.4
Pulse wave reflection index	0.2	0.3	0.4	0.6	0.5
Loud music exposure frequency	0.2	0.2	0.4	0.6	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	0.2	0.9
Comparative body size at age 10	0.2	0.4	0.8	0.9	-0.1
Worry too long after embarrassment	0.2	0.3	0.5	0.3	0.7
Pulse wave peak to peak time	0.2	0.2	0.3	-0.3	-0.5
Emphysema/chronic bronchitis	0.2	0.2	0.4	-0.6	-0.1
Medication: Allopurinol	0.2	0.3	0.5	-0.3	0.7
Number of full sisters	0.2	0.3	0.3	-0.6	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	0.6	0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.5	-0.1	-0.7
Leg fat-free mass (right)	0.2	1.0	1.5	-1.2	-0.6
Medication: Gliclazide	0.2	0.3	0.5	0.2	-0.7
Leg predicted mass (right)	0.2	1.0	1.6	-1.3	-0.6
Financial situation satisfaction	0.2	0.3	0.5	0.7	-0.1
Alcohol drinker status: Never	0.2	0.2	0.4	0.0	0.6
Number of operations (self-reported)	0.2	0.3	0.6	0.8	0.2
Unable to work because of sickness or disability	0.2	0.2	0.2	0.5	0.4
Supplements: Calcium	0.2	0.2	0.3	-0.5	-0.2
Basal cell carcinoma (self-reported)	0.2	0.2	0.4	0.6	0.3
Depressed Affect (Nagel 2018)	0.1	0.1	0.3	0.2	0.5
Neuroticism (Nagel 2018)	0.1	0.3	0.4	0.4	0.7
Schizophrenia vs Biploar Disorder	0.1	0.2	0.3	-0.5	-0.2
Worry (Nagel 2018)	0.1	0.3	0.5	0.7	-0.1
Prostate Cancer	0.1	0.2	0.2	0.4	0.3
Coronary Artery Disease (CAD)	0.1	0.1	0.1	-0.1	0.4
Crohns Disease (2012)	0.1	0.1	0.1	-0.3	-0.4
Schizophrenia (2014)	0.1	0.3	0.5	0.7	0.3
Triglycerides	0.1	0.1	0.1	0.3	-0.3
Blood Platelet Count	0.1	1.0	1.9	-1.4	0.2
Blood White Count	0.1	0.9	1.1	1.1	0.8
Heel T-Score	0.1	0.8	1.2	0.7	-1.1
Smoking Status	0.1	0.2	0.4	-0.6	-0.1
Allergy or Eczema	0.1	0.2	0.3	0.5	0.4
Neuroticism	0.1	0.1	0.2	-0.5	0.2
Hair Pigment	0.1	1.5	1.9	1.0	1.4
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.2	-0.4	0.4
Supplements: Zinc	0.1	0.1	0.1	0.4	0.1
Current tobacco smoking	0.1	0.2	0.4	-0.0	-0.6
Taking other prescription medications	0.1	0.1	0.3	0.5	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.5	0.7	-0.1
Waist circumference	0.1	0.2	0.4	0.2	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.2	0.4	0.2
Medication: Simvastatin	0.1	0.1	0.1	0.3	0.3
Neuroticism score	0.1	0.2	0.2	-0.5	-0.3
Impedance of arm (right)	0.1	0.4	0.5	-0.5	-0.7
Alcohol intake versus 10 years previously	0.1	0.1	0.2	-0.5	0.2
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	-0.5	-0.1
Pulse rate	0.1	0.2	0.4	0.3	0.6
Asthma	0.1	0.1	0.2	-0.0	-0.5
Depression (self-reported)	0.1	0.1	0.1	-0.0	-0.4
Arm fat mass (right)	0.1	0.4	0.5	0.7	0.6
Length of working week for main job	0.1	0.1	0.1	0.3	0.3
Breastfed as a baby	0.1	0.1	0.1	0.4	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.3	-0.2	0.5
Hair/balding pattern: Pattern 4	0.1	0.3	0.5	0.7	0.5
Blood clot in the leg (DVT)	0.1	0.1	0.2	-0.3	-0.4
Forced vital capacity (FVC), Best measure	0.1	0.5	1.0	0.3	1.0
Exposure to tobacco smoke outside home	0.1	0.2	0.4	0.6	0.1
Number of full brothers	0.1	0.1	0.2	0.2	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.3	-0.0	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	0.3	-0.4
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	0.3	0.2
Medication: Ibuprofen	0.1	0.1	0.1	0.4	-0.3
Medication: Omeprazole	0.1	0.2	0.2	-0.5	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.2	0.2	0.5
Suffer from ‘nerves’	0.1	0.1	0.3	0.5	-0.0
Overall health rating	0.1	0.2	0.3	0.2	0.5
Illnesses of siblings: Diabetes	0.1	0.2	0.3	0.1	-0.6
Mood swings	0.1	0.2	0.2	-0.4	-0.5
Qualifications: nursing, teaching	0.1	0.1	0.2	0.5	0.0
Eye problems/disorders: Cataract	0.1	0.2	0.3	-0.5	0.2
Asthma (self-reported)	0.1	0.2	0.4	-0.3	-0.6
Illnesses of father: None of the above (group 1)	0.1	0.2	0.2	0.4	-0.4
Smoking status: Current	0.1	0.1	0.1	0.3	-0.3
Arm fat mass (left)	0.1	0.4	0.5	0.7	0.5
Number of self-reported non-cancer illnesses	0.1	0.2	0.4	0.1	0.7
Wears glasses or contact lenses	0.1	0.1	0.1	0.3	0.3
High cholesterol (Self-reported)	0.1	0.1	0.3	0.1	0.5
Ever smoked	0.1	0.2	0.2	-0.5	-0.3
Age started oral contraceptive pill	0.1	0.2	0.3	0.6	-0.0
Commuting to job workplace: Cycle	0.1	0.1	0.1	-0.2	0.3
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.1	-0.4	-0.3
Bipolar Disorder or Schizophrenia	0.0	0.1	0.1	-0.1	-0.4
Depression (Nagel 2018)	0.0	0.0	0.0	0.0	0.2
Major Depression (MDD)	0.0	0.0	0.0	-0.1	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.1	0.1	-0.3	0.0
Tanning	0.0	0.5	0.7	-0.4	0.9
Relative age of first facial hair	0.0	0.1	0.2	-0.4	0.1
Trunk fat percentage	0.0	0.0	0.0	0.2	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.1	0.1	-0.4	-0.0
Trunk fat mass	0.0	0.2	0.3	-0.6	-0.3
Alcohol usually taken with meals	0.0	0.0	0.0	0.1	-0.1
Nervous feelings	0.0	0.0	0.0	-0.2	-0.1
Had other major operations	0.0	0.0	0.0	-0.0	-0.0
Forced vital capacity (FVC)	0.0	0.1	0.2	-0.0	0.4
Mouth/teeth dental problems	0.0	0.1	0.1	0.1	0.4
Time employed in main current job	0.0	0.0	0.1	-0.2	-0.1
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.1	0.1	0.3
Pulse wave Arterial Stiffness index	0.0	0.0	0.1	-0.1	0.2
Exposure to tobacco smoke at home	0.0	0.0	0.0	-0.1	-0.1
Tense / ‘highly strung’	0.0	0.0	0.0	0.2	0.1
Body fat percentage	0.0	0.2	0.2	0.4	0.4
Migraine (self-reported)	0.0	0.0	0.0	-0.1	0.2
Whole body fat mass	0.0	0.1	0.2	-0.5	-0.2
Leg fat mass (right)	0.0	0.0	0.1	0.2	0.3
Illnesses of father: Heart disease	0.0	0.1	0.1	0.1	0.3
Average weekly red wine intake	0.0	0.0	0.0	-0.1	0.1
Ever had bowel cancer screening	0.0	0.1	0.1	0.3	0.0
Mineral and other dietary supplements	0.0	0.1	0.1	-0.2	-0.3
Miserableness	0.0	0.0	0.1	0.1	-0.2
Guilty feelings	0.0	0.1	0.1	-0.2	0.3
Ever taken oral contraceptive pill	0.0	0.0	0.1	-0.3	-0.1
Medication: Atorvastatin	0.0	0.0	0.1	-0.3	0.1
Fractured/broken bones in last 5 years	0.0	0.1	0.1	0.3	-0.1
Ever depressed for a whole week	0.0	0.1	0.1	-0.2	-0.3
Heart disease (siblings)	0.0	0.1	0.1	-0.3	-0.1
Leg fat mass (left)	0.0	0.0	0.1	0.1	0.3

Hub : Genes

ZNF799

Models

Trait associations