[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr11:63,305,184-70,179,848

Best TWAS P=2.1e-33 · Best GWAS P=3.57e-29 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PRDX5	0.06	0.03	lasso	5	0.03	1.7e-03	6.19	-7.8	7.1e-15	-0.49	0.16	0.24	TRUE
2	GTEx	Adipose Subcutaneous	RAD9A	0.43	0.22	lasso	6	0.23	7.1e-19	-5.87	-5.6	2.7e-08	-0.04	0.00	1.00	FALSE
3	GTEx	Adipose Subcutaneous	RP11-554A11.9	0.34	0.13	enet	43	0.26	4.1e-21	-4.74	-5.5	4.6e-08	0.03	1.00	0.00	TRUE
4	GTEx	Adrenal Gland	LRP5	0.25	0.14	lasso	4	0.06	2.5e-03	4.58	5.3	1.1e-07	0.02	0.06	0.62	FALSE
5	GTEx	Artery Aorta	PPP1R14B	0.12	0.03	lasso	4	0.08	3.0e-05	-3.92	6.1	9.6e-10	0.30	0.51	0.15	FALSE
6	GTEx	Artery Aorta	RP11-554A11.9	0.37	0.18	enet	23	0.27	3.3e-15	-4.74	-6.2	4.2e-10	0.02	1.00	0.00	TRUE
7	GTEx	Artery Tibial	NDUFV1	0.04	0.07	lasso	3	0.04	2.4e-04	-5.23	-5.2	1.7e-07	0.00	0.04	0.92	FALSE
8	GTEx	Artery Tibial	RAD9A	0.39	0.26	lasso	2	0.24	3.5e-19	-5.87	-5.8	4.9e-09	-0.05	0.00	1.00	FALSE
9	GTEx	Artery Tibial	RP11-554A11.9	0.34	0.06	enet	35	0.22	4.0e-17	4.15	-6.1	1.1e-09	0.00	1.00	0.00	TRUE
10	GTEx	Brain Cerebellum	RP11-554A11.9	0.59	0.16	enet	29	0.33	1.4e-10	-1.13	-5.7	9.7e-09	0.03	0.39	0.06	FALSE
11	GTEx	Brain Frontal Cortex BA9	PACS1	0.17	0.14	enet	18	0.18	1.7e-05	3.12	-5.1	3.1e-07	0.04	0.28	0.05	FALSE
12	GTEx	Breast Mammary Tissue	KAT5	0.15	0.06	lasso	10	0.02	2.1e-02	-8.16	-8.7	3.7e-18	0.04	0.03	0.68	TRUE
13	GTEx	Breast Mammary Tissue (Male)	KAT5	0.05	-0.01	lasso	4	-0.01	7.4e-01	-8.27	-6.5	6.7e-11	0.05	0.02	0.35	FALSE
14	GTEx	Breast Mammary Tissue (Female)	PPP1R14B	0.10	0.06	lasso	2	0.08	2.0e-03	7.58	7.0	2.3e-12	0.31	0.05	0.05	FALSE
15	GTEx	Breast Mammary Tissue (Female)	RP11-554A11.9	0.40	0.25	enet	18	0.30	1.5e-09	-4.74	-6.8	9.2e-12	0.01	0.56	0.05	TRUE
16	GTEx	Cells Transformed fibroblasts	RP11-554A11.9	0.25	0.06	enet	18	0.14	2.0e-10	3.34	-7.4	1.6e-13	-0.04	0.99	0.00	TRUE
17	GTEx	Esophagus Mucosa	TPCN2	0.20	0.07	lasso	8	0.06	5.6e-05	4.21	5.7	9.4e-09	0.07	0.62	0.11	FALSE
18	GTEx	Esophagus Mucosa	PACS1	0.08	0.01	lasso	5	0.01	7.9e-02	4.37	-5.2	1.9e-07	0.05	0.38	0.09	TRUE
19	GTEx	Esophagus Mucosa	SIPA1	0.34	0.17	lasso	6	0.20	1.6e-13	-7.04	6.5	7.4e-11	0.00	0.96	0.04	FALSE
20	GTEx	Esophagus Mucosa	DOC2GP	0.16	0.14	lasso	5	0.11	1.0e-07	-5.23	5.2	2.2e-07	0.00	0.04	0.96	FALSE
21	GTEx	Esophagus Mucosa	RP11-554A11.9	0.23	0.18	lasso	3	0.18	4.0e-12	-4.74	-5.2	1.7e-07	-0.02	1.00	0.00	FALSE
22	GTEx	Esophagus Muscularis	NUDT8	0.07	0.05	lasso	2	0.03	9.9e-03	-5.23	-5.2	1.7e-07	0.01	0.03	0.90	FALSE
23	GTEx	Esophagus Muscularis	RAD9A	0.25	0.26	lasso	2	0.26	6.2e-16	-5.87	-5.9	3.3e-09	-0.05	0.00	1.00	TRUE
24	GTEx	Esophagus Muscularis	RP11-554A11.9	0.31	0.18	lasso	9	0.22	1.4e-13	-4.74	-5.5	3.9e-08	0.01	1.00	0.00	FALSE
25	GTEx	Heart Atrial Appendage	VEGFB	0.21	0.01	enet	21	0.07	3.0e-04	8.89	-8.7	2.4e-18	-0.65	0.01	0.93	TRUE
26	GTEx	Heart Left Ventricle	RP11-554A11.9	0.16	0.11	lasso	3	0.09	2.2e-05	-4.74	-5.2	1.6e-07	0.00	0.38	0.05	TRUE
27	GTEx	Muscle Skeletal	RP11-554A11.9	0.24	0.01	lasso	8	0.12	2.0e-11	4.15	-5.5	3.6e-08	0.00	0.94	0.00	FALSE
28	GTEx	Nerve Tibial	PRDX5	0.10	0.01	lasso	5	0.04	9.8e-04	6.43	-5.3	1.4e-07	-0.21	0.30	0.10	FALSE
29	GTEx	Nerve Tibial	RAD9A	0.53	0.24	lasso	10	0.23	5.6e-16	-5.87	-5.7	1.2e-08	-0.05	0.00	1.00	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	PRDX5	0.13	0.12	lasso	2	0.11	1.5e-06	7.65	-7.3	3.8e-13	-0.35	0.59	0.06	TRUE
31	GTEx	Skin Sun Exposed Lower leg	PRDX5	0.08	0.07	enet	16	0.05	1.0e-04	7.65	-5.7	1.3e-08	-0.22	0.75	0.01	FALSE
32	GTEx	Spleen	CTD-3074O7.5	0.29	0.03	enet	27	0.05	2.6e-02	-0.48	-5.9	4.4e-09	0.00	0.05	0.08	FALSE
33	GTEx	Testis	RAD9A	0.72	0.50	lasso	4	0.49	1.1e-24	-5.87	-5.8	6.1e-09	-0.05	0.00	1.00	FALSE
34	GTEx	Vagina	RP11-755F10.1	0.39	0.02	lasso	6	0.09	3.9e-03	3.26	5.6	1.7e-08	-0.11	0.08	0.23	FALSE
35	METSIM	Adipose	BANF1	0.10	0.06	bslmm	343	0.07	4.9e-10	-5.12	6.0	1.6e-09	-0.02	1.00	0.00	FALSE
36	METSIM	Adipose	LTBP3	0.03	0.00	bslmm	369	0.01	1.5e-02	0.15	5.2	1.7e-07	-0.05	0.09	0.12	FALSE
37	METSIM	Adipose	MYEOV	0.30	0.24	lasso	8	0.25	1.1e-37	6.87	-8.3	1.3e-16	0.04	1.00	0.00	TRUE
38	METSIM	Adipose	SART1	0.08	0.05	enet	26	0.05	1.1e-07	-5.04	6.8	9.0e-12	0.05	1.00	0.00	FALSE
39	METSIM	Adipose	VEGFB	0.12	0.06	enet	17	0.08	6.5e-12	10.19	-11.7	8.4e-32	-0.77	0.01	0.99	FALSE
40	NTR	Blood	BANF1	0.03	0.00	enet	10	0.02	1.1e-06	3.19	5.3	1.1e-07	0.05	0.17	0.13	TRUE
41	NTR	Blood	ORAOV1	0.04	0.02	lasso	2	0.02	2.3e-07	5.30	-5.3	1.1e-07	0.07	1.00	0.00	TRUE
42	ROSMAP	Brain Pre-frontal Cortex	DNAJC4	0.11	0.00	enet	31	0.02	4.2e-04	10.90	-7.4	1.4e-13	-0.51	0.00	0.94	TRUE
43	ROSMAP	Brain Pre-frontal Cortex	PPP6R3	0.04	0.01	blup	421	0.02	3.2e-04	3.64	-5.4	7.6e-08	0.07	0.69	0.07	TRUE
44	ROSMAP	Brain Pre-frontal Cortex	PRDX5	0.10	0.05	lasso	6	0.08	2.8e-10	4.01	-5.8	6.0e-09	-0.13	1.00	0.00	TRUE
45	ROSMAP	Brain Pre-frontal Cortex	CTSW	0.06	0.03	bslmm	328	0.03	3.6e-05	1.53	-5.8	6.1e-09	0.09	0.40	0.35	FALSE
46	ROSMAP	Brain Pre-frontal Cortex	VEGFB	0.10	0.07	enet	6	0.05	1.5e-07	10.90	-12.0	2.1e-33	-0.77	0.02	0.98	TRUE
47	ROSMAP	Brain Pre-frontal Cortex	DOC2GP	0.06	0.06	lasso	4	0.06	2.4e-08	-5.23	5.3	1.1e-07	-0.03	0.04	0.96	FALSE
48	YFS	Blood	BANF1	0.14	0.19	bslmm	342	0.21	8.3e-67	-4.95	5.5	4.3e-08	0.02	1.00	0.00	FALSE
49	YFS	Blood	CCDC88B	0.49	0.54	bslmm	346	0.59	1.9e-249	-4.13	5.2	1.6e-07	0.21	1.00	0.00	TRUE
50	YFS	Blood	GPR137	0.03	0.02	lasso	5	0.02	1.5e-08	7.58	6.8	7.7e-12	0.26	0.97	0.02	FALSE
51	The Cancer Genome Atlas	Breast Invasive Carcinoma	EIF1AD	0.02	0.03	blup	42	0.03	4.3e-07	-5.11	-5.4	7.8e-08	0.01	0.01	0.98	FALSE
52	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TSGA10IP	0.19	0.01	lasso	5	0.02	2.2e-02	-5.11	5.2	2.6e-07	0.02	0.01	0.82	FALSE
53	The Cancer Genome Atlas	Colon Adenocarcinoma	TBX10	0.11	0.08	lasso	2	0.07	7.5e-05	-5.46	-5.5	4.5e-08	0.03	0.00	0.99	TRUE
54	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SIPA1	0.06	0.04	blup	43	0.05	4.6e-06	-8.70	8.5	1.9e-17	0.00	0.00	0.99	FALSE
55	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	KCNK7	0.04	0.01	blup	42	0.01	1.2e-02	3.23	-5.9	4.3e-09	0.03	0.35	0.23	FALSE
56	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MAP3K11	0.06	0.03	lasso	4	0.03	2.1e-04	-8.70	8.4	5.5e-17	-0.01	0.00	0.97	FALSE
57	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SIPA1	0.04	0.00	blup	43	0.02	6.2e-03	-7.04	8.2	3.7e-16	0.02	0.01	0.40	FALSE
58	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRMT112	0.10	0.02	blup	28	0.05	4.7e-06	6.19	-5.9	4.0e-09	-0.41	0.00	1.00	FALSE
59	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EIF1AD	0.03	0.00	blup	42	0.01	2.5e-02	-4.12	-5.1	3.0e-07	0.03	0.01	0.31	FALSE
60	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SIPA1	0.09	0.03	blup	43	0.06	1.2e-07	-7.04	7.2	8.3e-13	-0.03	0.00	0.99	FALSE
61	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	VEGFB	0.06	0.00	blup	47	0.02	3.9e-03	11.21	-8.6	7.1e-18	-0.48	0.00	0.81	FALSE
62	The Cancer Genome Atlas	Prostate Adenocarcinoma	MAP3K11	0.06	0.02	blup	47	0.03	1.4e-04	-7.04	5.6	2.6e-08	0.03	0.05	0.33	FALSE
63	The Cancer Genome Atlas	Soft Tissue Sarcoma	EIF1AD	0.05	0.06	blup	42	0.02	1.3e-02	-5.00	-5.2	2.5e-07	0.00	0.01	0.90	FALSE
64	The Cancer Genome Atlas	Soft Tissue Sarcoma	NEAT1	0.09	0.04	blup	31	0.07	5.6e-05	3.86	5.3	1.1e-07	-0.08	0.02	0.93	FALSE
65	The Cancer Genome Atlas	Skin Cutaneous Melanoma	SNX32	0.51	0.26	blup	60	0.36	1.9e-10	1.66	5.3	9.8e-08	-0.11	0.27	0.64	FALSE
66	The Cancer Genome Atlas	Thyroid Carcinoma	CATSPER1	0.03	0.01	blup	41	0.02	3.4e-03	-5.04	5.3	1.1e-07	-0.02	0.01	0.73	FALSE