TWAS hub - TRMT112

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.157	0.0560	8.7e-04	0.102	NA	0.112	NA	0.095	5.6e-06	NA	2.0e-06	NA	1.3e-05
2	GTEx	Brain Cortex	0.206	0.0860	3.0e-03	0.051	NA	0.146	NA	0.012	1.6e-02	NA	7.8e-05	NA	1.4e-01
3	GTEx	Esophagus Mucosa	0.094	0.0390	2.2e-03	0.000	NA	0.016	NA	0.004	3.5e-01	NA	2.7e-02	NA	1.6e-01
4	GTEx	Heart Left Ventricle	0.234	0.0742	8.2e-05	0.130	NA	0.099	NA	0.117	2.1e-07	NA	6.3e-06	NA	8.7e-07
5	GTEx	Skin Sun Exposed Lower leg	0.109	0.0450	7.1e-04	0.030	NA	0.050	NA	0.063	1.5e-03	NA	5.8e-05	NA	6.3e-06
6	GTEx	Testis	0.385	0.0800	3.0e-08	0.250	NA	0.235	NA	0.295	1.8e-11	NA	8.3e-11	NA	1.4e-13
7	NTR	Blood	0.028	0.0112	4.3e-04	0.022	0.011	0.010	0.015	0.017	8.5e-08	1.5e-04	2.0e-04	7.3e-06	2.4e-06
8	ROSMAP	Brain Pre-frontal Cortex	0.135	0.0382	4.9e-09	0.085	0.076	0.086	0.086	0.111	4.2e-11	4.8e-10	3.9e-11	3.2e-11	4.7e-14
9	YFS	Blood	0.254	0.0382	0.0e+00	0.151	0.154	0.153	0.159	0.156	6.3e-47	7.6e-48	1.1e-47	1.4e-49	8.9e-49
10	TCGA	Brain Lower Grade Glioma	0.097	0.0402	6.0e-06	0.018	0.047	0.038	NA	0.035	3.6e-03	4.7e-06	3.3e-05	NA	7.5e-05
11	TCGA	Pancreatic Adenocarcinoma	0.156	0.1060	5.3e-03	0.052	0.036	0.026	NA	0.033	3.1e-03	1.2e-02	2.9e-02	NA	1.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Neuroticism (2016)	5.4	7.8	14.7	-0.2	3.8	3.3	3.3	2.7	2.4	2.9	3.3	2.8	2.8	0.3
Qualifications: NVQ or HND or HNC or equivalent	4.4	5.2	7.4	-1.9	-1.7	-2.5	-2.7	-2.7	-2.7	-2.6	-1.8	-2.4	-1.9	1.8
Nervous feelings	4.1	7.6	12.2	3.0	2.2	2.9	2.8	2.4	3.2	3.5	2.8	3.3	2.5	0.7
Loud music exposure frequency	4.1	4.5	9.6	-2.8	-1.4	-1.2	-3.1	-1.9	-2.6	-2.2	-2.4	-2.5	-1.3	0.2
Medication: Allopurinol	4.1	5.4	12.4	-2.3	-0.1	-0.2	-2.6	-3.0	-2.6	-2.4	-2.1	-1.8	-2.6	3.5
Depression (self-reported)	4.0	4.8	7.6	2.1	1.3	2.2	2.4	2.5	2.5	2.8	2.4	2.7	1.2	1.1
Ever had prostate specific antigen (PSA) test	4.0	4.6	7.6	0.7	2.5	1.9	2.4	1.6	2.7	2.5	2.5	2.8	1.3	1.6
Hand grip strength (right)	3.9	10.5	17.6	-3.2	-2.7	-2.7	-3.8	-3.0	-4.2	-3.8	-3.6	-3.7	-2.9	0.5
Hypothyroidism (self reported)	3.8	8.8	16.9	-1.1	-0.7	-3.0	-2.7	-4.1	-3.4	-3.8	-1.6	-3.4	-2.4	3.9
Seen doctor (GP) for nerves, anxiety, tension or depression	3.7	5.7	8.0	2.6	2.1	1.9	2.4	2.3	2.8	2.6	2.8	2.5	2.4	1.5
Illnesses of father: None of the above (group 1)	3.6	4.5	13.3	-1.4	2.4	0.7	1.6	2.8	1.3	1.8	2.2	0.9	3.6	-2.6
Supplements: Glucosamine	3.4	4.4	8.1	2.0	1.9	2.1	1.9	2.2	2.8	2.6	1.8	2.5	1.8	0.6
Tense / ‘highly strung’	3.4	5.6	7.7	1.7	2.6	2.2	2.7	1.9	2.4	2.7	2.7	2.8	2.8	0.8
Chronic bronchitis/emphysema (father)	3.2	3.8	7.4	-0.4	-1.9	-2.6	-2.2	-1.7	-2.1	-2.5	-1.7	-2.7	-1.5	0.2
Commuting to job workplace: Cycle	3.2	3.9	8.4	-0.6	1.7	1.9	2.9	1.8	2.1	2.2	2.1	2.3	2.1	-1.3
Gout (self-reported)	3.1	4.3	13.6	-2.7	0.7	0.6	-2.0	-2.5	-1.9	-1.7	-1.5	-1.2	-2.3	3.7
Breast cancer (self-reported)	3.1	3.7	6.2	2.1	1.7	1.7	2.5	2.3	1.8	2.3	2.0	2.4	0.3	-0.5
Supplements: Fish oil (including cod liver oil)	3.1	4.0	8.6	1.8	0.8	2.0	2.3	1.8	2.8	2.7	1.9	2.9	0.9	-0.1
Chronotype (morning person)	2.9	6.7	12.9	-2.4	-2.8	-3.2	-1.7	-2.6	-3.3	-2.4	-2.7	-1.7	-3.6	-0.6
Fed-up feelings	2.9	5.2	16.2	0.4	0.6	-1.5	-2.8	-3.2	-2.1	-2.5	-1.2	-2.3	-1.7	4.0
Leg pain on walking	2.9	3.7	6.1	-1.5	-2.0	-2.0	-2.2	-1.5	-2.5	-2.2	-1.8	-2.5	-0.6	-1.5
Supplements: Calcium	2.9	3.2	8.7	1.8	2.1	0.8	1.3	0.7	1.9	1.9	2.0	2.0	1.0	3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	2.8	3.7	9.4	1.2	1.0	2.3	2.3	1.7	2.1	2.8	1.4	3.1	0.5	0.7
Mineral and other dietary supplements	2.8	3.8	8.4	-2.4	-1.1	-1.2	-2.0	-1.4	-2.7	-2.6	-1.7	-2.9	-0.8	-0.7
Multivitamins +/- minerals	2.7	3.4	5.4	1.5	1.8	1.7	1.6	1.1	2.2	2.1	2.0	2.3	1.2	2.2
Hayfever, allergic rhinitis or eczema	2.5	5.4	13.2	1.2	0.2	3.6	2.2	2.4	3.2	3.1	1.5	3.3	0.6	-0.2
Severe depression (siblings)	2.4	2.7	4.7	1.3	0.8	1.5	2.0	2.2	1.8	2.2	1.4	2.0	1.0	-1.0
Type 2 Diabetes (T2D) (2018)	2.3	4.3	12.9	-0.5	-1.1	-1.6	-2.2	-2.6	-2.0	-1.9	-2.2	-1.2	-3.6	2.2
Medication: Co-codamol	2.3	2.6	5.8	1.4	1.3	1.5	1.6	2.4	1.4	1.7	1.9	1.4	1.5	-1.4
Had other major operations	2.3	2.8	12.0	-0.6	1.7	1.8	1.1	1.7	1.3	1.0	2.1	0.5	3.5	-0.9
Alcohol usually taken with meals	2.2	3.6	6.3	1.7	-0.2	1.7	2.3	2.5	2.2	2.1	2.3	2.2	0.9	-1.5
Breastfed as a baby	2.2	2.8	7.1	0.5	0.4	1.9	2.3	1.6	2.1	2.3	1.2	2.7	-0.2	-0.2
Allergy or Eczema	2.1	5.6	13.8	1.8	-0.1	3.3	1.9	2.4	3.3	3.3	1.4	3.7	-0.5	0.2
Length of working week for main job	2.1	2.3	5.6	-1.9	-0.6	-1.4	-1.9	-0.6	-1.6	-1.6	-0.9	-1.9	0.5	-2.4
Emphysema/chronic bronchitis	2.1	2.3	9.8	1.9	-3.1	-1.0	-0.1	-0.7	-0.4	0.3	-1.2	0.6	-2.7	1.2
Alcohol drinker status: Never	2.1	2.5	6.3	-1.6	0.4	-1.2	-1.6	-0.7	-1.9	-1.9	-0.9	-2.4	-0.0	-2.5
Risk taking	2.1	3.0	5.8	0.9	0.6	1.2	2.4	1.7	2.0	2.4	1.4	2.2	2.4	0.4
Heart disease (mother)	2.0	2.4	6.5	-1.1	-1.8	-0.6	-2.5	-1.4	-1.5	-1.7	-1.4	-1.5	-1.9	0.5
Average weekly champagne plus white wine intake	2.0	2.7	7.4	-0.1	2.7	1.7	1.6	1.5	1.5	1.4	1.9	1.4	2.2	-0.3
Primary Biliary Cirrhosis	1.9	2.7	5.4	-1.1	0.9	-2.0	-1.9	-1.5	-2.1	-1.9	-0.3	-2.0	-0.6	2.3
Suffer from ‘nerves’	1.9	3.0	4.2	1.7	1.7	2.0	2.0	1.8	1.5	1.8	2.0	1.6	1.9	-0.5
Age at First Birth	1.8	2.6	5.5	0.6	1.2	2.1	2.0	1.5	1.9	2.0	1.5	2.3	0.5	-0.4
Number of live births	1.8	2.6	6.6	0.5	1.7	2.5	1.6	2.2	1.2	1.1	2.6	1.0	1.0	0.4
Worry too long after embarrassment	1.8	3.1	8.1	0.3	1.7	1.8	1.6	1.9	1.5	1.1	2.9	0.7	2.7	-1.4
Mean time to correctly identify matches	1.8	3.4	7.5	0.8	-2.5	-1.9	-0.8	-2.7	-0.5	-0.7	-1.8	0.3	-2.6	2.7
Medication: Aspirin	1.8	2.4	7.0	0.5	-0.1	-2.1	-1.3	-2.0	-1.5	-1.4	-1.3	-0.9	-2.6	1.5
Financial situation satisfaction	1.8	2.3	5.2	-1.1	-0.8	-0.8	-2.0	-1.9	-1.5	-1.6	-1.7	-1.4	-2.3	0.6
Lupus	1.7	2.5	9.9	0.6	3.2	2.2	1.4	1.2	1.2	1.3	1.3	1.2	1.2	1.2
Hypothyroidism/myxoedema (self-reported)	1.7	3.3	9.2	-0.8	0.8	-1.8	-1.5	-2.4	-1.9	-2.3	-0.5	-2.1	-1.3	3.0
Mother’s age at death	1.7	2.1	4.3	-0.2	2.1	1.1	1.1	1.1	2.0	2.1	0.7	2.0	0.7	1.3
Worry (Nagel 2018)	1.6	3.4	7.3	1.7	2.7	2.1	1.7	0.8	2.0	2.0	1.7	2.0	1.9	0.8
Reaction Time	1.6	3.0	7.6	-0.1	-2.6	-1.8	-1.0	-2.8	-0.8	-0.8	-2.0	0.0	-1.8	2.4
Ever used hormone-replacement therapy (HRT)	1.6	2.0	5.4	0.7	1.2	2.3	0.9	1.8	1.7	1.5	1.5	1.5	0.5	0.7
Heart attack	1.6	2.1	8.1	-0.2	-1.6	-2.0	-0.9	-1.4	-1.3	-1.2	-1.3	-0.6	-2.8	0.2
Allergy	1.6	3.6	8.1	-1.2	0.9	-2.8	-1.9	-2.1	-2.3	-2.5	-1.0	-2.6	0.6	1.2
Pulse wave reflection index	1.6	2.0	7.9	1.2	-1.6	-0.4	-0.5	-1.6	-0.4	-0.6	-1.0	0.1	-2.8	2.3
Neck or shoulder pain in last month	1.6	2.3	3.9	0.6	1.5	1.5	1.0	2.0	1.9	1.8	2.0	1.5	1.8	-0.3
Illnesses of father: Heart disease	1.6	2.2	5.7	0.4	-2.2	-0.4	-1.4	-1.9	-1.0	-1.0	-1.4	-0.4	-1.9	2.4
Medication: Aspirin	1.6	2.1	7.9	0.8	-0.4	-2.0	-1.1	-1.8	-1.3	-1.1	-1.3	-0.6	-2.8	1.4
Number of self-reported non-cancer illnesses	1.6	2.7	7.8	1.9	-0.4	-1.8	-0.7	-1.6	-1.4	-0.9	-0.9	-0.6	-2.8	2.8
Cholesterol lowering medication	1.6	2.3	12.0	0.6	-0.0	-1.1	-0.8	-1.5	-1.5	-1.6	-0.7	-0.7	-3.5	1.7
Heart attack/myocardial infarction (self-reported)	1.6	2.0	8.6	0.1	-1.7	-1.9	-0.9	-1.4	-1.2	-1.2	-1.2	-0.5	-2.9	0.2
Blood Platelet Count	1.5	17.4	91.2	-3.1	3.4	2.0	2.7	5.6	0.2	0.2	4.3	-1.0	4.1	-9.6
Vitamin and mineral supplements	1.5	2.0	9.2	-1.4	-1.4	-0.5	-0.4	0.0	-1.5	-1.0	-1.6	-1.2	-1.2	-3.0
Average weekly fortified wine intake	1.5	1.7	3.5	0.9	-1.0	1.1	1.5	1.5	1.6	1.7	0.8	1.9	0.8	-1.0
Relative age voice broke	1.5	2.3	4.6	0.6	2.0	2.1	1.8	1.6	1.2	0.9	2.1	0.6	2.0	0.4
Medication: Levothyroxine sodium	1.5	2.6	5.0	-0.3	0.6	-2.0	-1.3	-2.2	-1.8	-2.1	-0.4	-2.0	-1.0	2.2
Hayfever/allergic rhinitis (self-reported)	1.5	1.9	5.6	-0.4	-2.4	-1.0	-1.7	-1.2	-1.1	-1.0	-1.5	-1.2	-2.0	0.1
Medication: Simvastatin	1.5	2.2	5.5	-0.6	0.5	-1.3	-1.6	-1.5	-2.0	-2.1	-0.7	-1.5	-2.3	0.8
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	6.8	-1.6	-2.6	-1.0	-0.6	-0.5	-1.2	-1.3	-1.0	-1.2	-0.3	-1.8
Osteoporosis (self-reported)	1.5	1.8	8.0	1.6	1.7	-0.1	0.5	0.2	0.8	1.0	1.3	0.9	1.4	2.8
Ever depressed for a whole week	1.5	1.8	3.6	1.4	0.6	1.3	1.6	1.4	1.1	1.5	1.9	1.6	0.7	1.1
Alcohol drinker status: Previous	1.5	1.7	4.0	-0.2	-0.8	-1.1	-1.1	-1.5	-1.2	-1.3	-1.5	-1.0	-2.0	1.6
Rheumatoid Arthritis	1.4	1.9	9.5	-0.1	3.1	0.8	1.3	0.1	0.8	0.6	1.6	0.7	1.3	1.7
Type 2 Diabetes (T2D) (2012)	1.4	1.6	5.7	0.6	-1.2	-1.0	-0.9	-1.1	-0.9	-0.1	-2.0	0.3	-2.4	1.4
Waist Hip Ratio (WHR)	1.4	6.3	34.7	1.9	-1.5	-1.3	0.7	-1.7	-0.9	0.3	-0.9	2.2	-5.9	4.1
Age when periods started (menarche)	1.4	3.5	10.0	-0.3	2.4	3.2	2.0	2.2	1.1	1.1	2.1	0.6	2.4	-1.1
Medication: Cholesterol lowering	1.4	2.2	5.6	-0.8	-0.5	-1.7	-1.3	-1.9	-1.7	-1.8	-1.0	-1.3	-2.4	0.9
Medication: Seretide 50 evohaler	1.4	1.6	2.9	1.5	-1.5	1.6	1.1	1.7	1.2	1.7	0.2	1.5	-0.2	-0.1
Ever had bowel cancer screening	1.4	1.7	4.3	2.1	0.3	1.0	1.3	1.2	1.6	1.5	1.4	1.3	0.8	0.7
Body Mass Index (BMI) (2010)	1.3	1.8	6.8	0.9	0.6	0.8	1.2	1.8	0.7	0.7	1.2	0.2	1.9	-2.6
HDL Cholesterol	1.3	2.1	8.8	-2.4	2.1	0.9	-0.0	0.9	0.7	0.4	1.3	-0.1	3.0	-0.3
Systolic Blood Pressure	1.3	6.3	22.2	1.0	0.8	-1.9	-1.8	-3.5	-2.3	-2.0	-2.4	-0.9	-4.7	3.3
Hand grip strength (left)	1.3	3.4	6.0	-2.3	-0.9	-1.1	-2.4	-1.6	-2.3	-2.3	-1.6	-2.3	-0.8	1.5
Stomach or abdominal pain in last month	1.3	1.7	3.9	-0.4	0.5	1.4	1.0	1.9	1.3	1.6	1.1	1.3	2.0	-0.8
Pulse wave Arterial Stiffness index	1.3	1.5	8.7	1.0	0.0	-0.3	-0.2	-0.9	-0.4	-0.2	-0.4	0.3	-2.3	3.0
Qualifications: College or University degree	1.3	4.2	24.7	-3.2	0.3	1.0	1.4	2.3	0.2	0.7	0.6	0.5	1.4	-5.0
Pain type(s) experienced in last month: Hip pain	1.3	1.7	4.1	-0.8	1.5	1.4	0.8	2.0	0.7	0.9	0.9	0.4	1.5	-2.0
Medication: Bendroflumethiazide	1.3	2.0	5.2	2.3	0.8	-1.8	-0.7	-1.6	-1.4	-1.6	-0.6	-1.4	-1.8	0.7
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.5	0.1	-1.6	-0.7	-1.5	-1.0	-1.3	-0.9	-1.5	-0.9	-1.6	1.1
Hair/balding pattern: Pattern 3	1.2	1.8	4.8	-0.7	0.1	-0.8	-1.4	-2.2	-1.1	-2.0	-1.5	-1.8	-0.8	0.8
Illnesses of mother	1.2	1.5	3.0	0.3	1.7	0.2	1.6	1.4	1.2	1.2	1.3	1.0	1.6	-0.8
Peak expiratory flow (PEF)	1.2	2.8	7.2	-1.1	1.9	1.8	1.7	2.0	0.8	0.7	2.0	0.7	1.7	-2.7
Medication: Amlodipine	1.2	1.7	5.5	1.2	2.4	0.8	1.7	0.6	1.1	1.2	1.4	1.5	0.4	0.7
Pulse wave peak to peak time	1.2	1.5	8.7	-1.4	0.0	0.3	0.0	0.7	0.2	0.1	0.2	-0.4	2.1	-3.0
Knee pain experienced in last month	1.2	1.9	6.2	0.3	-1.0	-1.8	-1.5	-1.2	-1.7	-1.8	-0.6	-2.5	0.4	0.6
Smoking status: Previous	1.2	1.7	10.8	0.3	3.3	1.2	0.7	0.4	0.7	0.7	0.9	0.6	0.7	1.9
Taking other prescription medications	1.1	1.6	10.9	0.6	2.2	0.5	0.8	-0.3	0.2	0.5	0.5	0.7	-0.3	3.3
Hip circumference	1.1	4.7	29.7	-1.8	-1.2	1.3	-0.2	2.0	-0.5	-0.8	0.2	-1.9	2.6	-5.5
Pulse rate	1.1	1.8	5.9	-0.3	1.8	1.0	1.1	2.2	0.1	0.6	1.5	0.2	1.1	-2.4
Long-standing illness, disability or infirmity	1.1	1.6	5.9	-0.8	-0.3	-0.7	-1.1	-1.1	-1.2	-0.5	-1.6	-0.6	-2.0	2.4
Eye problems/disorders: Glaucoma	1.1	1.3	3.6	-0.9	0.6	0.0	-1.6	-1.1	-1.3	-1.9	-0.8	-1.9	-0.3	-0.1
Neuroticism (Nagel 2018)	1.0	2.5	10.3	1.6	3.2	1.1	0.6	-0.1	0.9	0.5	1.8	0.2	2.1	1.9
Coronary Artery Disease (CAD)	1.0	1.2	2.7	-0.2	-1.6	-1.5	-0.9	-1.6	-1.0	-1.3	-0.9	-1.2	0.0	0.0
Mean Putamen Volume	1.0	1.1	1.8	-0.4	-0.7	-0.9	-1.2	-1.3	-1.0	-1.0	-1.4	-1.1	-1.1	1.3
Blood Eosinophil Count	1.0	7.6	26.3	-1.7	-4.9	-1.5	-1.3	-2.1	-1.3	-0.4	-4.3	1.1	-5.1	-0.4
Smoking Status	1.0	2.4	10.0	2.2	2.8	0.4	0.6	0.2	0.4	0.7	1.3	0.7	0.7	3.2
Neuroticism	1.0	2.4	7.1	1.5	2.7	1.7	1.3	0.3	1.4	1.2	1.7	1.3	1.6	1.6
Systolic blood pressure, automated reading	1.0	2.9	10.2	0.2	-0.7	-1.3	-2.0	-1.6	-1.8	-1.6	-1.9	-1.5	-3.2	0.9
Diabetes (mother)	1.0	1.2	6.6	-0.4	-1.6	-1.1	-0.6	0.5	-1.1	-0.7	-0.1	-0.7	-0.1	-2.6
Alcohol intake versus 10 years previously	1.0	1.5	9.9	1.1	0.7	0.7	0.3	-0.3	1.0	1.2	0.1	1.2	-0.2	3.2
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.1	2.4	-0.1	0.9	1.2	0.9	1.6	1.2	0.8	1.1	0.5	1.4	-1.2
Eye problems/disorders: Cataract	1.0	1.2	6.7	-0.7	-0.6	-0.9	-0.4	-1.0	-0.9	-0.8	-1.3	-0.2	-2.6	0.5
Unable to work because of sickness or disability	1.0	1.3	2.5	0.7	0.8	1.5	1.5	1.0	1.2	1.4	0.9	1.6	0.2	0.6
Basal cell carcinoma (self-reported)	1.0	1.1	4.9	0.9	-1.8	0.6	0.7	0.7	0.5	0.8	-0.5	0.7	-0.8	-2.2
Depressed Affect (Nagel 2018)	0.9	2.0	10.4	1.3	1.1	-0.7	-1.2	-1.9	-0.6	-1.1	-0.1	-1.1	-0.2	3.2
HbA1C	0.9	1.0	5.7	-0.1	-0.9	-0.5	-0.6	-0.9	-0.5	0.2	-1.2	0.5	-2.4	1.2
Ulcerative Colitis	0.9	1.4	4.2	0.3	2.0	0.6	1.1	0.8	1.0	1.1	1.5	1.1	0.7	1.6
BMI	0.9	5.4	34.3	1.0	-3.3	-0.2	-0.4	1.5	-1.3	-1.5	0.1	-2.4	0.7	-5.9
Hearing difficulty/problems: Yes	0.9	1.4	3.4	1.8	1.0	0.9	0.7	0.6	1.5	1.3	1.2	1.5	-0.2	1.3
High blood pressure (mother)	0.9	1.2	3.5	1.3	-0.6	1.9	0.8	0.9	1.4	1.4	0.4	1.5	-0.0	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	5.1	-0.9	2.2	1.8	0.7	0.7	0.7	0.7	1.7	0.7	0.7	0.6
Average weekly red wine intake	0.9	1.3	3.0	-0.0	-0.1	1.3	1.3	1.1	1.4	1.5	0.7	1.7	0.7	-1.3
Handedness (chirality/laterality): Left-handed	0.9	1.0	3.0	1.7	-1.1	0.6	0.8	-0.2	0.4	0.7	-0.2	1.2	-1.4	1.4
Loneliness, isolation	0.9	1.3	3.5	-0.1	-0.7	-0.8	-1.2	-1.2	-1.9	-1.6	-0.7	-1.6	-1.2	-0.0
Qualifications: nursing, teaching	0.9	1.4	10.6	-0.8	-0.3	0.7	1.1	1.2	0.5	0.4	-0.1	0.5	-0.3	-3.3
Ever smoked	0.9	1.6	9.9	0.6	2.5	0.3	0.3	-0.5	0.1	0.5	0.4	0.7	-0.1	3.1
Average weekly beer plus cider intake	0.9	1.3	3.0	0.2	0.3	-1.0	-1.0	-1.4	-1.6	-1.2	-1.7	-1.6	-0.2	0.6
Ovarian Cancer	0.8	1.1	3.5	-0.4	1.9	1.6	0.3	0.7	0.8	0.7	0.7	0.5	1.3	1.3
Fasting Glucose	0.8	0.9	1.8	0.5	0.9	1.3	1.0	1.1	1.2	1.2	0.7	1.3	0.3	-0.2
Cardiovascular Disease	0.8	2.8	8.4	2.9	1.1	-1.1	-0.4	-1.7	-0.8	-1.2	0.2	-0.2	-2.9	2.5
Respiratory disease	0.8	1.7	8.6	0.8	-2.9	-0.9	-0.3	-0.5	-0.5	-0.4	-1.0	-0.0	-2.6	-0.6
Lung FEV1/FVC ratio	0.8	4.3	9.7	0.1	1.1	1.7	2.4	2.9	1.2	1.5	3.1	1.3	2.0	-3.1
Average weekly spirits intake	0.8	0.9	3.6	-0.2	0.2	0.9	0.8	1.0	1.1	1.1	0.4	0.9	1.9	-0.8
Medication for hormone replacement therapy	0.8	0.8	3.0	-1.7	-0.6	0.1	-1.5	-0.3	-0.9	-0.9	-0.7	-1.1	0.2	-0.0
Maternal smoking around birth	0.8	1.2	6.5	0.0	1.3	-0.3	-1.3	-0.8	-0.9	-0.8	-0.3	-0.8	0.0	2.5
Medication: Lansoprazole	0.8	0.9	1.8	1.0	-0.4	0.7	1.1	1.2	0.8	1.2	1.0	1.4	-0.7	0.8
Medication: Paracetamol	0.8	1.4	7.0	0.4	2.0	-0.0	-0.3	0.6	0.7	0.6	1.1	-0.2	2.6	1.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.1	0.4	-0.4	1.5	1.0	1.4	1.5	1.4	0.7	1.0	1.8	-0.7
Glaucoma (self-reported)	0.8	0.9	2.3	-0.5	0.9	-0.0	-1.3	-1.1	-1.1	-1.5	-0.6	-1.5	-0.0	0.7
Chronic bronchitis/emphysema (mother)	0.8	0.9	2.8	-0.6	-0.6	-0.9	-0.4	-0.1	-1.1	-1.3	0.3	-1.7	1.0	-1.1
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.5	1.3	-1.6	-0.4	-0.5	-0.5	-0.3	0.2	-1.3	0.1	-1.0	1.6
Medication: Blood pressure	0.8	1.4	4.0	-0.1	0.5	-1.5	-0.8	-1.4	-1.6	-1.2	-1.2	-0.8	-2.0	-0.1
Number of full sisters	0.8	1.0	2.8	0.1	1.1	0.2	0.7	1.5	0.7	0.9	1.5	0.6	1.7	-0.2
Illnesses of siblings: Diabetes	0.8	1.0	6.3	0.9	-2.5	-1.0	-0.5	0.0	-0.4	0.1	-0.8	0.3	-1.4	-0.1
Diabetes diagnosed by doctor	0.8	1.4	5.7	-0.1	-0.8	-1.2	-0.9	-1.2	-1.2	-1.4	-0.5	-0.9	-2.4	0.8
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.2	0.7	0.5	1.5	0.9	0.7	1.5	1.2	1.1	1.2	1.5	1.2
Medication for cholesterol	0.8	1.2	5.9	-1.0	-0.3	0.2	0.7	1.3	0.9	1.2	0.2	0.6	2.4	-1.4
Arm fat mass (left)	0.8	3.1	18.8	-0.2	-2.1	0.3	-0.5	1.6	-1.0	-1.2	0.0	-2.1	0.9	-4.3
Medication: Atorvastatin	0.8	1.0	4.1	-0.3	1.0	-0.3	-0.4	-1.1	-0.6	-0.7	-0.3	-0.3	-2.0	1.7
Illnesses of father: High blood pressure	0.8	0.9	4.1	1.2	-0.6	0.7	0.7	-0.9	0.0	-0.0	-0.8	0.7	-2.0	1.3
Fractured/broken bones in last 5 years	0.8	1.0	4.8	-1.7	1.7	0.7	-0.5	-0.0	-0.1	0.3	0.3	0.1	0.6	2.2
Myopia	0.8	1.2	3.0	-0.4	0.8	-1.0	-1.4	-1.5	-1.1	-1.0	-1.0	-0.9	-0.6	1.7
Blood Red Count	0.7	6.6	36.5	0.4	-4.2	-0.3	-1.7	-1.8	-0.8	-0.6	-3.0	1.0	-6.0	1.2
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.0	-0.7	-1.0	-0.9	-1.1	-1.0	-0.8	-0.7	-0.9	-0.4	-1.4	0.4
Supplements: Zinc	0.7	0.7	2.5	0.8	-0.9	-0.6	0.6	-0.7	0.7	0.5	0.7	1.1	-0.6	1.6
Pack years adult smoking proportion	0.7	1.1	4.9	-0.4	-2.2	-0.8	-0.6	-0.8	-0.9	-0.9	-1.0	-0.6	-1.4	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	6.4	0.2	-2.5	-0.9	-0.8	-0.8	-0.7	-0.9	-1.3	-0.6	-1.8	-1.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.2	-0.8	1.5	-0.8	-0.7	-1.2	-0.4	-0.9	-0.4	-0.8	0.2	1.1
Serious illness, injury or assault to yourself	0.7	0.8	3.1	0.6	0.3	0.8	1.1	0.7	0.7	1.4	0.3	1.7	-0.7	0.2
High blood pressure	0.7	1.9	9.2	3.0	1.5	-0.4	0.2	-1.1	-0.3	-0.5	0.5	-0.1	-1.8	2.0
Body mass index (BMI)	0.7	2.8	15.6	1.0	-2.2	0.5	0.2	2.0	-0.3	-0.6	0.8	-1.5	1.3	-4.0
Number of incorrect matches in round	0.7	1.1	3.5	0.3	-1.2	0.2	1.2	0.1	1.4	1.3	-0.1	1.4	0.7	1.9
Past tobacco smoking	0.7	1.4	8.1	-0.4	-2.8	-0.6	-0.7	-0.2	-0.2	-0.5	-0.8	-0.5	-0.2	-2.1
Time employed in main current job	0.7	0.9	3.2	-0.7	1.8	1.2	0.9	0.2	0.7	0.6	0.5	0.8	1.3	-0.0
Father’s age at death	0.7	1.0	1.9	-1.0	0.1	1.3	1.1	0.8	1.2	0.9	0.6	1.2	0.4	-1.4
Prospective memory result	0.7	0.8	4.0	1.0	0.2	-0.0	0.6	0.4	0.8	0.6	1.0	0.4	1.2	2.0
Arm fat mass (right)	0.7	3.0	18.9	-0.3	-1.7	0.4	-0.3	1.8	-0.9	-1.0	0.2	-2.0	1.2	-4.3
Number of children fathered	0.7	0.8	1.3	-1.1	1.1	-1.2	-0.4	-0.2	-0.9	-1.0	0.5	-1.1	0.8	-0.9
Migraine (self-reported)	0.7	0.9	3.5	1.8	-1.9	-0.5	0.1	-0.6	0.0	-0.2	-0.3	0.2	-1.4	-0.1
Age at last live birth	0.7	1.0	2.9	-1.2	1.1	0.0	-0.5	-0.3	-0.8	-1.4	0.2	-1.7	1.6	-0.3
Family relationship satisfaction	0.7	0.9	2.5	0.7	0.2	0.9	0.7	0.7	1.3	0.9	1.3	0.8	1.6	0.7
Hypertension (Self-reported)	0.7	1.8	9.1	3.0	1.7	-0.3	0.6	-0.6	-0.2	-0.2	0.7	0.3	-1.9	1.8
Arm fat percentage (left)	0.7	2.7	15.0	-0.0	-2.0	0.0	-0.7	1.3	-1.0	-1.3	-0.0	-2.1	0.8	-3.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	3.1	-1.0	1.3	0.8	-0.5	-0.2	0.0	-0.5	0.1	-0.8	1.8	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.2	-0.4	-1.5	-0.5	-0.6	-0.8	-0.9	-1.2	-0.1	-0.9	-1.4	0.2
Guilty feelings	0.7	1.1	4.6	-0.9	2.1	1.1	1.1	0.5	0.1	0.1	1.5	0.2	1.2	0.0
Number of operations (self-reported)	0.7	1.1	5.2	-2.3	-0.0	0.1	-0.2	0.3	-1.1	-0.9	-0.3	-1.1	0.0	-1.8
Age started oral contraceptive pill	0.7	0.9	4.4	2.1	-1.2	-1.0	-0.1	-0.4	-0.2	-0.5	0.2	-0.4	-1.5	0.2
Vascular/heart problems diagnosed by doctor	0.7	1.9	9.2	-3.0	-1.2	0.9	-0.2	1.0	0.5	0.7	-0.5	0.1	2.2	-1.5
Pack years of smoking	0.7	1.0	4.8	0.1	-2.2	-0.8	-0.5	-0.9	-0.8	-0.8	-0.9	-0.4	-1.5	0.4
Bipolar Disorder or Schizophrenia	0.6	1.4	11.3	0.7	-0.7	-1.1	0.1	-0.5	0.7	0.9	0.1	0.9	-0.0	3.4
Schizophrenia (2018)	0.6	1.3	11.1	0.6	-1.0	-0.8	-0.4	-0.7	0.1	0.4	-0.5	0.4	-0.0	3.3
Breast Cancer	0.6	1.3	3.0	0.8	0.2	1.7	1.2	1.2	1.2	1.2	1.5	1.5	0.3	0.6
LDL Cholesterol	0.6	1.0	2.0	0.8	1.3	0.7	1.1	1.2	0.9	0.8	1.4	0.6	1.4	0.3
Schizophrenia (2014)	0.6	1.3	7.1	1.2	-0.3	0.1	0.5	0.3	0.8	1.4	0.2	1.4	0.4	2.7
Heel T-Score	0.6	4.6	20.0	0.8	-4.0	1.4	0.9	1.6	0.2	0.2	-0.3	0.7	-2.7	-4.5
Number of treatments/medications taken	0.6	1.1	6.4	1.7	0.8	-0.6	-0.2	-0.4	0.0	0.3	0.0	0.5	-1.2	2.5
Diabetes (father)	0.6	0.8	3.2	-0.1	-1.3	0.3	-0.1	-0.1	-0.2	-0.5	-0.6	-0.1	-1.6	-1.8
Medication: Atenolol	0.6	0.7	2.8	0.9	0.6	1.1	0.8	-0.2	0.3	0.5	-0.4	1.0	-1.7	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	6.6	0.0	-2.0	0.0	0.2	0.1	-0.1	-0.1	-0.7	0.5	-1.6	-2.6
Neuroticism score	0.6	1.3	2.7	1.1	1.6	1.0	0.8	0.3	0.8	0.9	1.5	0.9	1.4	1.4
Arm fat percentage (right)	0.6	2.5	14.2	-0.1	-1.7	-0.0	-0.6	1.5	-0.9	-1.2	0.2	-2.0	0.9	-3.8
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.0	0.0	-0.1	-0.2	-0.5	-1.1	-0.7	-0.6	-1.2	-0.6	-1.2	1.4
Birth weight of first child	0.6	1.0	4.0	-0.4	-0.1	-2.0	-0.7	-0.4	-1.4	-1.3	-0.1	-1.5	-0.4	0.4
Whole body fat mass	0.6	2.4	14.4	0.0	-1.7	0.4	-0.6	1.5	-0.9	-1.0	0.0	-1.9	0.9	-3.8
Pulse rate, automated reading	0.6	2.1	14.9	-1.1	-0.3	-0.3	-0.3	1.3	-1.5	-0.9	0.5	-1.1	-0.5	-3.9
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.0	0.3	-0.4	-1.4	-1.4	-0.8	-0.8	-0.9	-0.1	-1.0	-0.2	0.8
Mood swings	0.6	1.2	7.6	1.6	0.8	-0.1	-0.7	-1.0	-0.2	-0.3	0.1	-0.5	0.6	2.7
Asthma (self-reported)	0.6	1.1	5.5	0.6	-2.3	-0.1	-0.3	0.1	-0.5	-0.5	-0.6	-0.4	-1.7	-1.6
Osteoarthritis (self-reported)	0.6	0.8	3.6	-1.9	1.3	0.4	0.0	0.8	-0.2	0.3	-0.1	-0.2	1.3	-0.7
Miserableness	0.6	1.0	8.9	-0.3	0.8	0.6	-0.2	-0.7	0.5	0.0	0.4	-0.2	0.4	3.0
Wears glasses or contact lenses	0.6	0.6	1.5	-0.6	-0.8	-0.6	-0.7	-0.2	-0.9	-1.2	-0.4	-1.2	-0.9	-0.8
Hearing aid user	0.6	0.6	2.0	0.9	1.2	0.1	0.8	0.2	0.5	1.0	-0.1	0.9	0.4	1.4
Medication: Blood pressure	0.6	1.1	4.9	2.2	0.9	0.2	0.1	-0.5	-0.3	-0.4	0.2	0.0	-2.1	1.1
High cholesterol (Self-reported)	0.6	1.1	5.2	0.9	0.4	0.0	0.0	-0.9	-0.3	-0.3	0.4	0.6	-2.3	2.2
Medication: Paracetamol	0.6	0.9	4.0	0.6	1.3	0.2	-0.3	0.8	0.9	0.7	1.0	0.0	2.0	0.4
Medication: Lisinopril	0.6	0.8	1.8	-0.8	0.5	-0.5	-0.9	-0.9	-1.1	-1.3	-0.6	-1.2	-0.9	-0.7
Irritability	0.6	1.1	2.8	-1.7	1.1	-0.0	-1.5	-1.1	-0.7	-0.5	-0.8	-0.6	0.8	1.4
Schizophrenia vs Biploar Disorder	0.5	0.6	2.2	-0.8	0.4	1.2	-0.0	0.8	0.5	0.4	0.8	0.0	1.5	-0.6
Bipolar Disorder (2011)	0.5	0.5	1.3	0.9	0.1	-0.6	0.9	0.3	1.0	1.0	0.1	1.1	0.0	0.0
Crohns Disease (2012)	0.5	0.8	4.6	0.6	1.2	-0.2	0.1	0.2	-0.1	-0.0	1.4	-0.2	0.9	2.1
Blood White Count	0.5	3.6	7.8	-2.1	0.6	-1.2	-1.6	-2.8	-2.5	-2.6	-1.2	-1.5	-2.2	1.5
Trunk fat percentage	0.5	2.1	13.7	0.2	-1.2	0.6	-0.3	1.9	-0.5	-0.6	0.5	-1.4	1.1	-3.7
Trunk fat mass	0.5	2.2	14.3	-0.0	-1.4	0.8	-0.4	1.7	-0.6	-0.7	0.2	-1.6	1.1	-3.8
Waist circumference	0.5	1.6	8.8	-0.1	-2.2	0.5	-0.0	0.9	-1.0	-0.7	-0.2	-0.9	-1.0	-3.0
Hearing difficulty/problems with background noise	0.5	0.7	3.8	1.4	0.4	0.8	-0.2	-0.2	0.9	0.6	0.5	0.4	0.1	2.0
Had menopause	0.5	0.6	2.3	-0.8	-0.3	1.0	0.4	1.5	0.8	1.0	0.6	0.8	-0.0	-0.5
Illnesses of siblings	0.5	0.7	2.8	-0.4	1.4	0.9	0.7	0.4	0.5	0.0	1.0	-0.1	1.7	-0.7
Weight	0.5	2.5	16.0	-0.5	-1.6	0.9	-0.4	1.4	-0.9	-1.0	-0.1	-1.8	0.9	-4.0
Qualifications: A levels/AS levels or equivalent	0.5	1.2	7.3	-2.1	0.3	0.1	0.8	0.3	-0.4	-0.4	-0.3	0.1	0.1	-2.7
Asthma	0.5	1.0	4.5	0.5	-2.1	-0.0	-0.5	0.2	-0.4	-0.5	-0.4	-0.3	-1.8	-1.5
Headache pain in last month	0.5	0.9	3.3	1.8	0.4	0.7	0.7	0.7	1.2	0.9	1.0	1.0	0.2	0.8
Birth weight	0.5	1.1	3.4	-1.4	0.6	-1.1	-0.4	0.6	-0.5	-0.8	0.5	-1.4	1.8	-1.1
Body fat percentage	0.5	2.0	12.5	0.5	-1.5	0.4	-0.3	1.7	-0.5	-0.8	0.4	-1.5	0.9	-3.5
Age at first live birth	0.5	0.9	4.0	-2.0	1.3	0.2	-0.4	-0.6	-0.5	-0.8	-0.3	-0.8	1.3	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.8	-0.5	0.7	0.9	0.4	1.3	0.4	0.7	0.6	0.5	-0.1	-1.3
Leg fat mass (right)	0.5	2.0	11.0	0.8	-1.9	0.3	-0.5	1.3	-0.9	-0.9	-0.1	-1.7	0.6	-3.3
Alcohol intake frequency.	0.5	1.1	2.8	-0.8	-0.6	-0.9	-1.0	-0.7	-1.3	-1.7	-0.4	-1.6	-1.1	0.1
Overall health rating	0.5	1.1	3.5	1.9	-0.8	-1.0	-1.0	-1.0	-1.0	-1.0	-0.4	-1.2	-0.8	0.7
Chest pain or discomfort	0.5	0.7	3.0	-0.9	1.0	1.7	0.4	1.2	0.2	0.3	0.7	0.2	-0.0	-1.0
Friendships satisfaction	0.5	0.6	2.0	0.0	-0.3	0.8	1.0	0.9	0.4	0.4	0.8	0.5	1.0	-1.4
Pain experienced in last month	0.5	0.8	2.1	-1.5	-0.9	-0.3	-0.3	-0.5	-0.6	-0.6	-0.7	-0.1	-1.3	-1.4
Leg fat mass (left)	0.5	1.9	10.6	0.8	-1.9	0.4	-0.4	1.4	-0.8	-0.8	0.1	-1.6	0.5	-3.2
Depression (Nagel 2018)	0.4	0.5	2.6	0.5	1.0	0.2	-0.1	-0.6	0.4	0.2	0.5	-0.0	1.1	1.6
Crohns Disease (2017)	0.4	0.8	5.4	-0.6	1.0	-0.3	-0.5	-0.1	-0.6	-0.4	1.1	-0.4	0.6	2.3
Irritable Bowel Disease (IBD)	0.4	0.9	5.3	-0.7	1.2	-0.8	-0.6	-0.4	-0.7	-0.4	0.7	-0.5	0.3	2.3
Verbal and Numeric Reasoning (VNR)	0.4	1.0	5.7	-1.8	-0.2	-0.2	-0.3	0.1	-0.9	-0.8	-0.4	-0.6	-0.7	-2.4
Lung FVC	0.4	2.2	5.2	0.4	0.5	1.4	0.8	1.1	2.0	1.6	1.5	1.4	2.3	2.2
Relative age of first facial hair	0.4	0.8	3.6	-0.6	1.9	0.8	0.2	0.8	-0.1	-0.3	1.0	-0.8	1.4	0.0
Ever had hysterectomy (womb removed)	0.4	0.4	1.3	0.5	-1.0	0.2	0.4	0.7	-0.1	0.3	-0.3	0.4	-1.0	-1.1
Leg fat-free mass (left)	0.4	2.2	12.9	-1.1	-1.3	0.9	-0.4	0.9	-1.1	-1.0	-0.4	-1.7	1.0	-3.6
Leg predicted mass (left)	0.4	2.2	13.6	-1.1	-1.3	0.9	-0.4	0.9	-1.1	-1.0	-0.4	-1.7	1.0	-3.7
Financial difficulties in last 2 years	0.4	0.6	3.5	0.5	1.0	0.1	-0.2	-0.4	0.6	0.2	0.7	0.4	-0.4	1.9
Mouth/teeth dental problems	0.4	0.6	4.2	-2.0	-0.5	-0.5	0.3	-0.5	0.1	0.0	-0.5	0.1	0.8	-0.8
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	4.9	-1.7	0.9	0.8	0.7	0.9	0.5	0.3	0.7	0.2	2.2	-1.4
Happiness	0.4	0.5	1.0	-0.9	-0.3	0.1	-0.7	-0.5	-1.0	-0.9	-0.7	-0.9	-0.4	-0.7
Mouth/teeth dental problems: Dentures	0.4	0.6	2.2	0.3	0.1	-0.4	-1.1	-0.3	-0.9	-0.9	-0.2	-1.1	-1.5	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	3.8	-1.8	1.5	1.5	0.8	0.9	0.8	0.3	0.8	0.3	2.0	-1.1
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.9	0.7	0.6	0.1	0.1	-0.5	-0.0	-0.2	0.0	0.4	-1.2	1.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.0	-1.0	0.5	0.5	1.0	0.9	0.4	0.3	0.4	0.5	0.0	-1.7
Medication: Ventolin 100micrograms inhaler	0.4	0.6	3.6	-0.1	-0.3	1.9	0.0	0.2	0.7	0.4	0.4	0.9	-1.0	0.2
Leg fat percentage (right)	0.4	1.5	8.1	1.4	-1.5	-0.1	-0.3	1.3	-0.6	-0.7	0.1	-1.3	0.3	-2.9
Comparative body size at age 10	0.4	1.1	3.8	1.5	-1.5	-0.2	-0.3	0.3	-0.4	-0.8	0.3	-1.5	0.5	-1.9
Health satisfaction	0.4	0.5	1.5	1.2	-0.7	0.5	0.4	0.9	0.4	0.7	0.8	0.8	-0.2	-0.1
Eye problems/disorders: None of the above	0.4	0.4	2.8	-0.2	0.0	-0.3	0.4	0.6	0.3	0.4	0.7	-0.1	1.7	-0.6
Had major operations	0.4	0.5	1.3	0.1	0.7	1.1	0.7	1.1	0.5	0.5	0.5	0.6	-0.6	-0.7
Supplements: Vitamin C	0.4	0.4	1.8	-0.2	-1.4	-1.0	-0.5	-0.6	-0.4	-0.5	-0.2	-0.2	-0.7	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	2.6	1.0	0.2	0.2	0.1	0.6	-0.1	0.3	0.2	0.4	-1.6	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	3.9	-2.0	0.4	0.1	0.1	0.3	0.0	0.2	-0.1	0.1	1.3	-1.4
Back pain experienced in last month	0.4	0.6	1.0	0.8	0.9	0.9	0.9	1.0	0.5	0.8	0.7	0.5	0.8	-0.4
Commuting to job workplace: Public transport	0.4	0.4	1.6	-0.5	0.3	0.6	0.4	0.8	0.5	0.7	-0.3	0.8	0.7	-1.3
Leg fat percentage (left)	0.4	1.4	7.0	1.4	-1.5	-0.0	-0.1	1.3	-0.5	-0.6	0.4	-1.2	0.4	-2.6
Bipolar Disorder (2018)	0.3	0.5	1.5	0.5	0.2	-0.7	0.7	0.1	1.0	0.9	0.8	0.9	-0.0	1.2
Intelligence (Savage-Jansen 2018)	0.3	1.0	6.8	-0.5	-0.4	-0.2	-0.3	0.4	-0.9	-0.7	-0.3	-0.5	-1.5	-2.6
Alzheimer’s Disease (including proxy)	0.3	0.4	1.4	-0.7	-0.5	0.1	-0.2	-1.2	0.2	-0.4	-0.5	-0.0	-0.5	1.2
Major Depression (MDD)	0.3	0.3	2.1	0.9	1.4	0.0	0.7	0.0	0.0	0.0	0.0	0.5	0.0	0.0
Triglycerides	0.3	0.5	2.8	0.8	-1.2	0.1	-0.3	-0.4	-0.7	-0.2	-0.4	-0.0	-1.7	0.2
Sensitivity / hurt feelings	0.3	0.5	1.7	0.3	0.6	-0.5	-0.1	-0.6	-1.3	-1.1	0.4	-1.1	0.1	0.2
Medication: Metformin	0.3	0.4	2.0	-0.3	0.0	-0.5	0.1	-0.4	-1.0	-0.8	-0.1	-0.6	-1.4	0.2
Townsend deprivation index at recruitment	0.3	0.5	1.7	-0.0	0.7	1.0	0.5	0.7	0.4	0.8	0.0	0.3	1.3	0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	2.5	-1.6	0.3	-0.1	-0.4	-0.0	-0.7	-0.2	-0.4	-0.0	-0.6	-0.6
Impedance of leg (left)	0.3	1.3	5.9	0.3	2.2	0.0	-0.1	-0.6	0.6	0.8	-0.0	1.4	-0.5	2.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.2	0.4	0.8	0.5	0.5	0.4	0.4	0.4	1.1	0.5	0.1	1.1
Qualifications: None of the above	0.3	0.6	3.4	0.8	1.1	0.2	0.1	-0.0	0.4	0.3	0.8	-0.0	0.9	1.9
Diabetes (self-reported)	0.3	0.5	1.7	0.2	-0.3	-0.5	-0.8	-0.8	-0.6	-0.8	-0.2	-0.6	-1.3	0.7
Fluid intelligence score	0.3	0.7	5.0	0.1	-0.3	0.6	0.5	0.2	-0.4	-0.4	-0.0	-0.0	-1.1	-2.2
Impedance of arm (right)	0.3	1.4	7.3	-2.7	2.3	-0.3	-1.0	-0.5	-0.6	-0.5	-0.6	-0.3	0.0	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.0	-1.0	-0.4	-0.6	-0.9	-0.7	-0.7	-0.8	-0.1	-0.8	-0.5	1.0
Falls in the last year	0.3	0.4	2.4	-0.5	0.4	0.7	0.2	0.7	0.3	0.3	0.5	-0.2	1.6	-0.7
Lung cancer (father)	0.3	0.4	1.2	0.8	-0.8	-0.7	-0.3	0.2	-0.6	-0.0	-0.8	-0.4	0.1	-1.1
Impedance of arm (left)	0.3	1.3	6.5	-2.5	1.8	-0.2	-1.3	-0.8	-0.6	-0.7	-0.9	-0.3	-0.4	0.3
High blood pressure (siblings)	0.3	0.4	1.4	0.7	-0.4	0.3	0.2	0.2	0.4	1.0	-0.2	1.2	-0.8	0.7
Exposure to tobacco smoke outside home	0.3	0.5	1.7	0.4	0.2	-0.3	0.7	1.3	0.1	0.6	0.8	0.2	0.6	-1.1
Wheeze or whistling in the chest in last year	0.3	0.6	1.4	0.7	-1.0	1.2	0.3	0.5	0.8	0.8	-0.1	1.0	-0.9	0.1
Medication for pain relief, constipation, heartburn	0.3	0.5	1.3	-1.0	-1.1	0.8	0.5	0.1	-0.1	-0.3	-0.3	0.1	-1.0	-1.0
Angina (self-reported)	0.3	0.5	1.8	-0.0	0.3	-1.3	-0.6	-0.3	-0.6	-0.7	-0.8	-0.7	-0.9	0.2
Medication: Omeprazole	0.3	0.3	1.4	-0.3	-0.5	-0.3	-0.6	-0.2	-0.3	0.1	-0.9	0.3	-1.2	0.2
Leg fat-free mass (right)	0.3	1.7	10.2	-1.0	-1.3	0.8	-0.3	0.8	-0.9	-0.9	-0.3	-1.5	0.9	-3.2
Medication: Gliclazide	0.3	0.4	1.9	-0.2	-0.7	0.2	0.2	-0.0	-0.6	-0.1	-0.5	0.2	-1.4	-0.9
Smoking status: Current	0.3	0.5	1.6	1.3	-0.9	-1.1	-0.2	-0.3	-0.7	-0.3	-0.0	-0.3	-0.5	0.7
Whole body water mass	0.3	1.4	8.2	-1.1	-0.6	1.0	-0.3	0.6	-0.9	-0.8	-0.5	-1.4	0.8	-2.9
Leg predicted mass (right)	0.3	1.7	10.0	-1.0	-1.2	0.9	-0.3	0.8	-1.0	-0.9	-0.3	-1.6	1.0	-3.2
Basal metabolic rate	0.3	1.7	11.2	-0.8	-0.8	1.1	-0.2	1.0	-0.8	-0.7	-0.2	-1.4	1.0	-3.4
Arm fat-free mass (left)	0.3	1.3	9.1	-0.5	-0.8	0.9	0.1	1.1	-0.7	-0.4	-0.1	-1.1	0.7	-3.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.9	0.5	0.9	0.2	0.2	0.5	0.3	0.3	0.9	-0.2	1.4	-0.6
Arm predicted mass (left)	0.3	1.3	9.0	-0.5	-0.8	1.0	0.0	1.1	-0.7	-0.4	-0.2	-1.1	0.7	-3.0
Alzheimer’s Disease (in mother)	0.2	0.2	1.4	-0.1	-0.3	-0.0	0.1	-0.9	0.5	-0.2	-0.4	-0.0	-0.0	1.2
Alzheimer’s Disease (in father)	0.2	0.2	1.7	0.1	0.5	1.3	-0.2	0.2	0.4	0.2	0.4	0.3	-0.1	-0.3
Ulcerative Colitis (UC)	0.2	0.4	1.2	-0.5	1.1	-1.0	-0.2	-0.3	-0.4	-0.4	0.4	-0.4	-0.1	1.0
Prostate Cancer	0.2	0.2	0.9	0.9	-0.4	-0.2	-0.3	-0.3	0.3	0.3	-0.4	0.2	0.7	0.5
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.4	-1.2	0.7	0.4	0.1	-0.4	-0.4	-0.1	0.1	0.0	-0.1	0.4
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	1.3	-0.6	0.2	-0.0	0.4	-0.2	-0.7	-0.2	-0.2	0.2	-1.1	0.3
Angina	0.2	0.3	1.3	-0.0	0.4	-1.1	-0.4	-0.1	-0.5	-0.5	-0.6	-0.6	-0.6	-0.2
Impedance of leg (right)	0.2	1.0	4.7	-0.1	2.2	-0.0	-0.3	-0.5	0.3	0.6	-0.4	1.1	-0.6	1.8
Current tobacco smoking	0.2	0.3	1.5	1.2	-0.6	-0.7	-0.2	-0.0	-0.6	-0.1	0.0	-0.1	-0.5	0.5
Sitting height	0.2	1.7	5.5	-2.4	-0.1	0.5	-1.2	-0.7	-0.9	-1.0	-1.7	-1.0	-0.9	-2.1
Hair/balding pattern: Pattern 2	0.2	0.2	0.9	-0.0	-1.0	-0.8	-0.1	0.5	-0.4	0.0	-0.4	-0.3	-0.1	-0.6
Forced vital capacity (FVC)	0.2	0.8	4.5	-2.1	0.9	0.1	-0.3	-0.2	0.2	-0.1	-0.4	-0.1	1.7	0.2
Pain all over the body in last month	0.2	0.3	1.3	0.2	-0.7	-0.8	0.2	0.1	0.2	0.4	0.2	0.3	0.2	1.2
Medication: Ramipril	0.2	0.3	1.0	0.6	0.6	0.2	0.3	0.6	-0.3	-0.0	0.7	0.0	-0.2	-1.0
Trunk fat-free mass	0.2	0.9	5.2	-1.0	-0.2	1.2	-0.1	0.5	-0.6	-0.4	-0.4	-0.9	0.7	-2.3
Noisy workplace	0.2	0.2	1.1	0.2	0.2	1.0	0.4	0.2	0.4	0.5	0.4	0.4	-0.2	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.1	0.5	0.7	-0.1	0.2	-0.2	0.4	0.2	0.6	0.1	1.1	1.0
Trunk predicted mass	0.2	0.9	5.5	-1.0	-0.2	1.2	-0.1	0.5	-0.6	-0.4	-0.4	-0.9	0.7	-2.4
Standing height	0.2	2.4	11.9	-3.5	1.1	0.8	-1.4	-1.0	-1.5	-1.0	-2.0	-0.9	-0.8	-0.8
Exposure to tobacco smoke at home	0.2	0.2	1.0	0.4	-1.0	0.3	0.0	0.4	-0.1	-0.0	0.4	0.0	-0.9	-0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.8	-0.2	-0.5	0.2	-0.2	0.7	-0.1	0.0	0.2	0.1	0.1	-1.4
Blood clot in the leg (DVT)	0.2	0.2	1.3	0.3	0.7	0.0	0.1	0.2	0.0	0.1	0.7	-0.3	1.1	-0.3
Forced vital capacity (FVC), Best measure	0.2	0.7	4.0	-2.0	1.3	0.8	-0.2	-0.2	0.3	-0.2	-0.1	0.0	1.2	0.2
Arm fat-free mass (right)	0.2	1.1	7.1	-0.1	-0.8	1.2	0.1	1.0	-0.4	-0.1	-0.1	-0.8	0.8	-2.7
Number of full brothers	0.2	0.3	0.8	0.7	0.1	0.3	-0.4	0.8	0.0	-0.3	0.9	-0.4	0.3	-0.7
Shortness of breath walking on level ground	0.2	0.2	1.0	-0.2	-0.4	0.3	0.3	0.5	-0.0	0.1	0.4	0.3	-1.0	-0.3
Arm predicted mass (right)	0.2	1.1	7.1	-0.0	-0.8	1.3	0.1	1.0	-0.4	-0.2	-0.1	-0.8	0.7	-2.7
Comparative height size at age 10	0.2	0.9	2.8	-1.6	0.2	-0.8	-0.4	-1.2	-0.8	-0.4	-1.7	0.1	-1.1	0.2
Whole body fat-free mass	0.2	1.4	8.2	-1.0	-0.8	1.1	-0.2	0.7	-0.8	-0.6	-0.5	-1.3	0.8	-2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	2.0	-0.2	-1.4	-0.3	0.6	0.3	0.4	-0.1	0.4	-0.0	0.7	-0.4
Ever taken oral contraceptive pill	0.2	0.2	1.0	1.0	-0.3	0.3	-0.2	0.1	0.7	0.2	0.8	0.3	0.2	0.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.8	0.3	-0.5	0.0	0.1	0.3	0.1	0.5	-0.4	0.6	-0.9	0.1
Heart disease (siblings)	0.2	0.2	0.7	-0.8	-0.3	0.0	-0.6	-0.0	-0.4	-0.3	-0.1	-0.3	-0.8	-0.1
Impedance of whole body	0.2	0.9	4.1	-1.2	2.0	-0.4	-0.8	-0.8	-0.1	-0.0	-0.7	0.5	-0.5	1.5
Height	0.1	1.8	6.0	-1.3	2.5	2.1	0.7	1.2	0.5	1.2	0.2	1.1	-0.1	-1.7
Hair Pigment	0.1	4.2	17.7	-0.6	4.2	2.5	1.2	1.8	0.9	1.3	1.4	0.7	3.4	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.5	0.1	0.3	-0.4	-0.1	-0.3	-0.1	-0.1	0.7	-0.5	0.7	0.7
Qualifications: CSEs or equivalent	0.1	0.2	0.7	-0.3	0.1	0.3	-0.1	0.0	-0.3	-0.4	0.2	-0.8	0.7	-0.4
Worrier / anxious feelings	0.1	0.2	0.7	0.8	0.6	0.5	0.4	-0.1	0.1	0.4	0.6	0.6	-0.1	0.5
Hair/balding pattern: Pattern 4	0.1	0.2	0.9	0.3	-0.1	-0.1	0.5	0.3	0.1	0.7	0.3	0.7	-0.2	-0.9
Medication: Ibuprofen	0.1	0.1	0.5	0.2	-0.2	-0.6	-0.4	-0.4	0.0	-0.0	0.0	-0.1	0.4	0.7
Commuting to job workplace: Walk	0.1	0.1	0.3	0.3	0.5	0.3	-0.0	0.1	0.5	0.1	0.3	0.1	0.1	0.3
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	0.2	-0.0	0.1	-0.2	-0.0	0.2	-0.2	0.2	-0.4	0.6	0.5
Diastolic blood pressure, automated reading	0.1	0.3	1.4	-0.0	-0.6	0.9	0.1	0.1	-0.2	0.0	-0.8	0.4	-1.2	-0.4
Tanning	0.0	0.5	2.5	0.5	-1.0	-1.1	0.2	0.3	0.4	0.3	-0.2	0.2	-0.3	-1.6

Hub : Genes

TRMT112

Models

Trait associations