Hub : Traits :

Prospective memory result

3 significantly associated models · 3 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 15 82084934 83879618 3 2 6.7e-08 1.2e-08 0.4 98 RP11-152F13.3 RP13-996F3.3

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 2.67 1 0 0 0 1 RP13-996F3.3
Verbal and Numeric Reasoning (VNR) 5.36 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Schizophrenia 2.63 1 0 0 0 1 RP11-152F13.3
Blood Red Count 1.77 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Smoking Status 4.29 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Lung FVC 2.39 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Hair Pigment 0.65 1 1 3 0 1 RP11-152F13.3
Tanning 1.77 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Hand grip strength (left) 1.54 1 0 0 0 1 RP13-996F3.3
Vitamin and mineral supplements 3.48 1 0 0 0 1 RP11-152F13.3
Impedance of leg (right) 1.98 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Current tobacco smoking 4.03 1 0 0 0 1 RP11-152F13.3
Maternal smoking around birth 3.59 1 0 0 0 1 RP11-152F13.3
Stomach or abdominal pain in last month 4.69 1 0 0 0 1 RP11-152F13.3
Impedance of leg (left) 2.34 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Alcohol usually taken with meals 5.04 1 0 0 0 1 RP11-152F13.3
Fluid intelligence score 6.32 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Father's age at death 3.26 1 0 0 0 1 RP11-152F13.3
Frequency of tiredness / lethargy in last 2 weeks 4.55 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Forced expiratory volume in 1-second (FEV1) 1.77 1 0 0 0 1 RP11-152F13.3
Qualifications: A levels/AS levels or equivalent 2.82 1 0 0 0 1 RP11-152F13.3
Lung cancer (father) 3.71 1 0 0 0 1 RP13-996F3.3
Forced expiratory volume in 1-second (FEV1), Best measure 2.05 1 0 0 0 1 RP11-152F13.3
Seen doctor (GP) for nerves, anxiety, tension or depression 3.10 1 0 0 0 1 RP13-996F3.3
Peak expiratory flow (PEF) 1.39 1 0 0 0 1 RP11-152F13.3
Gout (self-reported) 2.38 1 0 0 0 1 RP13-996F3.3
Forced vital capacity (FVC), Best measure 1.67 1 0 0 0 1 RP11-152F13.3
Leg fat percentage (right) 1.18 1 0 0 0 1 RP11-152F13.3
Comparative body size at age 10 4.84 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Reason for reducing amount of alcohol drunk: Health precaution 2.89 1 0 0 0 1 RP11-152F13.3
Qualifications: College or University degree 3.20 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Medication: Allopurinol 3.18 1 0 0 0 1 RP13-996F3.3
Chest pain or discomfort 7.20 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Qualifications: NVQ or HND or HNC or equivalent 6.51 1 0 0 0 1 RP13-996F3.3
Commuting to job workplace: Walk 8.36 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Smoking status: Current 4.70 1 0 0 0 1 RP11-152F13.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.13 1 0 0 0 1 RP11-152F13.3
Financial situation satisfaction 5.07 1 0 0 0 1 RP13-996F3.3
Commuting to job workplace: Public transport 8.02 2 0 0 0 1 RP11-152F13.3 RP13-996F3.3
Leg fat percentage (left) 1.41 1 0 0 0 1 RP11-152F13.3
Irritability 2.63 1 0 0 0 1 RP13-996F3.3
Diastolic blood pressure, automated reading 1.69 1 0 0 0 1 RP11-152F13.3

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 0 0.0000 1.21
GTEx Adipose Visceral Omentum 0 0.0000 1.23
GTEx Adrenal Gland 0 0.0000 1.20
GTEx Artery Aorta 0 0.0000 1.23
GTEx Artery Coronary 0 0.0000 1.17
GTEx Artery Tibial 0 0.0000 1.25
GTEx Brain Caudate basal ganglia 0 0.0000 1.18
GTEx Brain Cerebellar Hemisphere 0 0.0000 1.22
GTEx Brain Cerebellum 0 0.0000 1.22
GTEx Brain Cortex 0 0.0000 1.21
GTEx Brain Frontal Cortex BA9 0 0.0000 1.26
GTEx Brain Hippocampus 0 0.0000 1.21
GTEx Brain Hypothalamus 0 0.0000 1.18
GTEx Brain Nucleus accumbens basal ganglia 0 0.0000 1.20
GTEx Brain Putamen basal ganglia 0 0.0000 1.18
GTEx Breast Mammary Tissue 0 0.0000 1.21
GTEx Breast Mammary Tissue (Male) 0 0.0000 1.21
GTEx Breast Mammary Tissue (Female) 0 0.0000 1.20
GTEx Cells EBV-transformed lymphocytes 0 0.0000 1.23
GTEx Cells Transformed fibroblasts 0 0.0000 1.29
GTEx Colon Sigmoid 0 0.0000 1.18
GTEx Colon Transverse 0 0.0000 1.22
GTEx Esophagus Gastroesophageal Junction 0 0.0000 1.15
GTEx Esophagus Mucosa 0 0.0000 1.25
GTEx Esophagus Muscularis 0 0.0000 1.20
GTEx Heart Atrial Appendage 0 0.0000 1.16
GTEx Heart Left Ventricle 1 0.0654 1.20
GTEx Liver 0 0.0000 1.35
GTEx Lung 0 0.0000 1.21
GTEx Muscle Skeletal 0 0.0000 1.23
GTEx Nerve Tibial 0 0.0000 1.23
GTEx Ovary 0 0.0000 1.22
GTEx Pancreas 0 0.0000 1.22
GTEx Pituitary 0 0.0000 1.18
GTEx Prostate 0 0.0000 1.12
GTEx Skin Not Sun Exposed Suprapubic 0 0.0000 1.25
GTEx Skin Sun Exposed Lower leg 0 0.0000 1.27
GTEx Small Intestine Terminal Ileum 0 0.0000 1.17
GTEx Spleen 0 0.0000 1.28
GTEx Stomach 0 0.0000 1.26
GTEx Testis 0 0.0000 1.27
GTEx Thyroid 1 0.0250 1.26
GTEx Uterus 0 0.0000 1.22
GTEx Vagina 0 0.0000 1.23
GTEx Whole Blood 0 0.0000 1.27
METSIM Adipose 0 0.0000 1.23
NTR Blood 0 0.0000 1.33
ROSMAP Brain Pre-frontal Cortex 1 0.0228 1.25
YFS Blood 0 0.0000 1.21
CommonMind Brain Pre-frontal Cortex 0 0.0000 1.26
TCGA Breast Tumor 0 0.0000 1.31
TCGA Breast Normal 0 0.0000 1.21
TCGA Ovarian Tumor 0 0.0000 1.24
TCGA Prostate Tumor 0 0.0000 1.26