TWAS hub - TSKS

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.1097	0.0314	1.7e-06	0.093	0.050	0.092	0.087	0.097	9.7e-14	4.6e-08	1.4e-13	5.8e-13	2.7e-14
2	YFS	Blood	0.4094	0.0390	0.0e+00	0.202	0.255	0.253	0.254	0.220	3.6e-64	8.1e-83	3.4e-82	2.1e-82	2.7e-70
3	TCGA	Breast Invasive Carcinoma	0.0243	0.0097	1.4e-05	0.020	0.027	0.021	NA	0.025	4.6e-05	2.1e-06	3.2e-05	NA	5.0e-06
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.0622	0.0287	5.8e-04	0.046	0.031	0.040	NA	0.045	5.8e-06	1.8e-04	2.5e-05	NA	7.4e-06
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.0861	0.0324	2.7e-06	0.072	0.065	0.065	NA	0.067	1.6e-08	7.6e-08	8.9e-08	NA	5.2e-08
6	TCGA	Lung Adenocarcinoma	0.0748	0.0313	1.0e-04	0.049	0.044	0.072	NA	0.076	2.0e-06	7.0e-06	7.6e-09	NA	3.6e-09
7	TCGA	Lung Squamous Cell Carcinoma	0.0482	0.0217	3.3e-04	0.070	0.024	0.055	NA	0.060	2.3e-08	7.9e-04	7.5e-07	NA	2.3e-07
8	TCGA	Prostate Adenocarcinoma	0.0844	0.0308	9.4e-06	0.028	0.049	0.028	NA	0.026	6.0e-04	6.4e-06	5.9e-04	NA	8.0e-04
9	TCGA	Thyroid Carcinoma	0.1520	0.0610	3.7e-05	0.077	0.057	0.072	NA	0.077	5.9e-08	3.0e-06	1.5e-07	NA	5.5e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Illnesses of father: High blood pressure	5.1	6.3	12.0	-0.4	-2.2	-3.5	-3.3	-1.1	-1.5	-3.3	-2.5	-2.8
Gout (self-reported)	4.9	6.7	12.0	2.1	1.1	2.2	2.9	2.1	2.6	3.0	3.5	3.0
Pulse wave peak to peak time	3.9	4.6	8.5	2.0	1.9	2.9	2.0	2.2	1.9	1.8	2.4	1.8
Pulse wave Arterial Stiffness index	3.6	4.2	8.2	-1.8	-1.9	-2.9	-2.0	-2.1	-1.8	-1.8	-2.3	-1.8
Pulse wave reflection index	3.6	4.5	7.6	-1.3	-2.2	-2.8	-2.7	-1.7	-1.5	-2.4	-1.8	-2.2
Relative age voice broke	3.4	5.2	8.8	1.9	1.8	2.9	1.9	3.0	2.3	2.2	1.5	2.7
Ever had prostate specific antigen (PSA) test	3.4	4.0	5.4	-2.3	-1.9	-2.1	-1.9	-2.3	-2.2	-1.7	-1.1	-2.0
Age when periods started (menarche)	2.6	6.2	11.2	2.2	1.6	1.5	2.8	1.7	3.1	3.2	2.1	3.4
Chronic bronchitis/emphysema (father)	2.6	3.0	7.1	1.7	1.7	2.1	1.1	2.1	1.5	1.0	2.7	1.1
Handedness (chirality/laterality): Left-handed	2.6	3.1	6.6	-0.3	-1.1	-1.7	-2.5	-0.3	-1.2	-2.6	-2.1	-2.3
Asthma	2.4	4.8	6.7	-2.0	-1.3	-2.2	-2.1	-2.6	-2.3	-2.2	-2.4	-2.3
Medication: Ventolin 100micrograms inhaler	2.4	3.1	7.5	-2.3	-0.4	-1.5	-1.2	-2.7	-2.0	-1.2	-2.0	-1.5
High blood pressure (siblings)	2.4	3.4	5.0	-2.0	-2.2	-2.1	-1.1	-2.2	-2.1	-1.3	-1.6	-1.5
Respiratory disease	2.3	5.1	9.6	-1.4	-0.6	-1.8	-3.1	-1.3	-2.1	-3.1	-2.4	-3.0
Illnesses of siblings	2.3	3.2	4.9	2.0	1.8	1.8	1.4	2.0	2.2	1.6	1.5	1.8
Alcohol drinker status: Previous	2.3	2.6	4.1	-1.2	-0.9	-1.5	-2.0	-0.9	-1.5	-2.0	-2.0	-2.0
Exposure to tobacco smoke at home	2.2	2.5	5.7	0.5	1.0	2.4	1.7	1.2	1.5	2.1	1.1	1.9
Sensitivity / hurt feelings	2.1	3.6	8.2	-1.4	-0.0	-0.9	-2.4	-1.3	-2.5	-2.9	-1.0	-2.6
Serious illness, injury or assault to yourself	2.0	2.5	3.5	-1.4	-1.1	-1.6	-1.9	-1.4	-1.8	-1.8	-1.2	-1.8
Mouth/teeth dental problems	2.0	3.0	6.6	-1.5	-1.4	-2.6	-1.4	-2.5	-1.5	-1.4	-1.3	-1.5
Hayfever/allergic rhinitis (self-reported)	2.0	2.7	6.5	1.3	2.5	1.2	2.0	1.0	1.6	1.8	1.2	1.6
Average weekly spirits intake	1.9	2.4	4.2	1.2	1.8	1.4	2.1	1.0	1.3	1.7	1.5	1.8
Chronic bronchitis/emphysema (mother)	1.9	2.2	4.1	1.3	0.4	1.8	1.5	2.0	1.7	1.7	0.2	1.7
Qualifications: nursing, teaching	1.8	2.8	4.2	-1.5	-1.8	-2.0	-1.3	-1.4	-1.8	-1.4	-1.9	-1.7
Breast cancer (self-reported)	1.8	2.2	6.8	-1.7	-2.6	-1.6	-0.5	-1.2	-1.1	-0.2	-1.9	-0.5
Ever used hormone-replacement therapy (HRT)	1.7	2.2	5.4	-2.2	1.0	0.0	-0.7	-2.2	-2.3	-1.1	0.1	-1.3
Mouth/teeth dental problems: Dentures	1.6	2.7	8.6	1.7	-0.1	2.2	0.9	2.9	1.9	1.2	0.1	1.5
Average weekly beer plus cider intake	1.6	2.3	5.1	1.6	0.3	1.0	1.2	2.3	2.0	1.5	0.8	1.8
Prostate Cancer	1.5	2.1	3.3	0.9	0.7	1.6	1.3	1.5	1.6	1.7	1.8	1.8
Pulse rate	1.5	2.5	4.0	1.9	0.4	-0.2	2.0	1.3	1.9	1.8	1.2	2.0
Medication: Lansoprazole	1.5	1.8	4.2	0.3	1.9	2.0	1.4	0.9	0.5	1.3	1.6	0.8
Birth weight of first child	1.5	2.7	4.4	1.6	2.1	1.3	1.7	1.8	1.6	1.5	0.9	1.9
Headache pain in last month	1.5	2.5	8.5	0.0	-1.9	-2.9	-1.7	-0.4	-0.6	-1.8	-1.7	-1.2
Shortness of breath walking on level ground	1.5	1.8	3.0	1.3	1.2	1.1	1.4	0.8	1.6	1.4	1.1	1.7
Number of full sisters	1.5	1.8	3.2	-0.7	-1.6	-1.7	-1.4	-1.0	-0.8	-1.1	-1.8	-1.4
Asthma (self-reported)	1.5	2.9	4.3	-1.6	-0.9	-1.8	-1.6	-2.1	-1.8	-1.7	-1.9	-1.8
Commuting to job workplace: Public transport	1.5	1.8	3.8	1.3	1.1	2.0	1.1	1.3	1.4	1.1	1.7	0.9
Age started oral contraceptive pill	1.5	1.9	3.2	-1.3	-1.2	-1.5	-1.0	-1.8	-1.5	-1.3	-1.1	-1.4
Had menopause	1.4	1.8	3.9	-1.9	-0.7	-0.2	-1.1	-1.7	-2.0	-1.2	-0.9	-1.4
Medication: Lisinopril	1.4	1.8	2.7	-1.2	-1.2	-1.3	-1.0	-1.6	-1.4	-1.1	-1.5	-1.5
Number of operations (self-reported)	1.4	2.1	2.8	-1.3	-1.2	-1.3	-1.7	-1.3	-1.5	-1.6	-1.4	-1.7
Ever had hysterectomy (womb removed)	1.3	1.4	2.4	-1.0	-0.9	-1.4	-0.8	-1.4	-1.2	-1.0	-1.5	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.0	12.0	1.2	1.4	2.0	1.5	1.2	1.1	1.2	3.5	1.3
Pulse rate, automated reading	1.3	4.1	10.3	0.6	1.1	1.0	3.0	0.6	1.6	3.2	1.8	2.9
Ever depressed for a whole week	1.3	1.6	2.8	1.7	1.1	1.3	0.6	1.7	1.4	0.5	1.6	1.0
Basal cell carcinoma (self-reported)	1.3	1.5	4.0	-0.0	-1.2	-0.1	-1.7	0.5	-1.1	-2.0	-0.8	-1.8
Lung FEV1/FVC ratio	1.2	6.1	12.1	2.5	-0.5	1.2	2.9	2.1	3.1	3.0	1.9	3.5
Migraine (self-reported)	1.2	1.5	8.4	-0.3	-1.3	-2.9	-0.7	-0.8	-0.5	-0.7	-1.1	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	2.8	-1.2	-0.6	-1.2	-0.8	-1.7	-1.4	-1.0	-0.1	-1.2
Age at First Birth	1.1	1.6	3.4	0.9	1.8	1.7	1.1	1.6	1.1	0.0	1.0	1.1
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	3.3	-1.0	-0.7	-1.2	-1.8	-0.9	-1.2	-1.5	-0.2	-1.4
Average weekly fortified wine intake	1.1	1.3	6.0	-0.2	-2.4	-1.8	-0.6	-0.6	-0.3	-0.5	-0.9	-0.5
Trunk fat-free mass	1.1	6.4	26.6	-1.0	-3.2	-5.2	-1.9	-2.5	-1.2	-1.9	-1.5	-1.5
Illnesses of mother	1.1	1.4	5.8	0.6	1.7	1.7	0.4	0.8	0.3	0.2	2.4	0.0
Trunk predicted mass	1.1	6.4	27.1	-1.0	-3.1	-5.2	-1.9	-2.5	-1.2	-1.9	-1.5	-1.5
Breastfed as a baby	1.1	1.3	2.7	-1.3	-0.4	-0.6	-0.8	-1.6	-1.6	-1.1	-0.8	-1.4
Glaucoma (self-reported)	1.1	1.3	2.9	-1.7	0.1	-0.6	-1.1	-1.6	-1.4	-0.8	-0.9	-1.1
Emphysema/chronic bronchitis	1.1	1.2	2.3	-0.9	-0.3	-0.4	-1.5	-1.1	-1.1	-1.4	-1.1	-1.4
Mean time to correctly identify matches	1.1	2.1	3.9	-1.7	-1.2	-0.0	-1.9	-0.8	-1.5	-1.4	-2.0	-1.5
Arm predicted mass (right)	1.1	5.5	22.0	-0.9	-3.0	-4.7	-1.6	-2.4	-1.3	-1.8	-1.5	-1.4
Chest pain or discomfort	1.1	1.6	2.7	-1.4	-0.8	-1.0	-1.0	-1.6	-1.6	-1.2	-1.0	-1.5
Whole body fat-free mass	1.1	6.3	24.5	-1.0	-3.3	-5.0	-1.9	-2.5	-1.2	-1.9	-1.6	-1.6
Whole body water mass	1.1	6.1	24.1	-1.0	-3.3	-4.9	-1.9	-2.5	-1.2	-1.8	-1.5	-1.5
Pain type(s) experienced in last month: Hip pain	1.1	1.3	2.3	-1.3	-1.5	-1.2	-0.7	-1.2	-1.3	-0.8	-1.3	-1.0
HbA1C	1.0	1.1	4.7	0.8	2.2	1.4	0.5	0.7	0.7	0.0	1.1	0.3
Impedance of leg (right)	1.0	4.9	17.3	0.6	3.3	4.2	1.5	2.0	1.1	1.7	1.3	1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.4	10.2	0.9	1.2	2.0	1.3	0.9	0.7	1.0	3.2	1.0
Diverticular disease/diverticulitis (self-reported)	1.0	1.1	3.1	-1.5	-0.0	-0.7	-0.7	-1.8	-1.4	-0.7	-0.2	-1.2
Medication: Levothyroxine sodium	1.0	1.7	7.0	-1.6	-0.2	-0.7	-1.6	-0.3	-1.1	-1.1	-2.6	-0.9
High blood pressure (mother)	1.0	1.4	4.4	-1.2	-0.8	-1.5	-0.3	-1.4	-1.1	-0.5	-2.1	-0.5
Impedance of leg (left)	1.0	4.6	15.8	0.6	3.4	4.0	1.5	1.6	1.0	1.6	1.5	1.7
Financial difficulties in last 2 years	1.0	1.4	3.2	0.3	0.6	1.1	1.5	0.7	1.1	1.8	0.9	1.7
Number of live births	1.0	1.4	3.5	-1.9	-0.1	-0.8	-0.9	-1.8	-1.7	-0.9	-0.5	-1.1
Leg fat percentage (right)	1.0	3.5	8.9	1.5	-0.2	1.0	2.2	2.0	2.1	2.4	0.4	3.0
Comparative height size at age 10	1.0	5.7	8.1	-2.0	-2.1	-2.6	-2.8	-2.4	-2.3	-2.8	-1.3	-2.7
Average weekly red wine intake	1.0	1.5	3.6	1.8	1.9	1.2	0.8	1.2	1.0	0.3	1.2	0.8
Loneliness, isolation	1.0	1.4	3.4	-1.4	-1.9	-1.1	-0.9	-1.1	-0.8	-0.4	-1.6	-0.6
Leg predicted mass (right)	1.0	5.1	18.2	-1.0	-3.2	-4.3	-1.7	-2.3	-1.2	-1.7	-1.4	-1.5
Number of self-reported non-cancer illnesses	1.0	1.7	3.0	-0.2	-1.3	-1.7	-1.5	-0.6	-0.6	-1.5	-1.7	-1.5
Eye problems/disorders: Glaucoma	1.0	1.2	2.6	-1.6	-0.1	-0.3	-1.3	-1.2	-1.3	-0.9	-0.9	-1.1
Supplements: Calcium	1.0	1.1	1.6	-1.2	-1.1	-1.0	-0.9	-0.9	-1.1	-0.8	-1.1	-1.1
Alzheimer’s Disease (in mother)	0.9	1.1	2.0	-0.5	-0.7	-1.4	-1.1	-0.9	-1.2	-1.4	-0.6	-1.3
Diabetes (mother)	0.9	1.2	4.0	1.4	1.1	0.3	0.9	0.7	1.0	0.6	2.0	0.9
High blood pressure	0.9	2.6	5.3	-0.9	-1.4	-1.6	-1.9	-1.2	-1.1	-1.7	-2.3	-1.7
Stomach or abdominal pain in last month	0.9	1.1	2.4	-0.9	-1.6	-1.4	-0.5	-0.9	-0.8	-0.4	-1.5	-0.6
Leg predicted mass (left)	0.9	4.6	16.4	-0.8	-3.2	-4.0	-1.7	-1.9	-0.9	-1.6	-1.6	-1.3
Past tobacco smoking	0.9	1.6	3.8	-1.9	-0.5	-0.5	-0.4	-1.6	-1.7	-0.4	-1.9	-1.1
Qualifications: None of the above	0.9	1.9	2.9	0.9	1.5	1.7	1.1	1.4	1.6	1.6	0.5	1.5
Time employed in main current job	0.9	1.0	2.5	-0.8	-0.3	-0.0	-1.0	-0.9	-1.5	-1.4	-0.3	-1.6
Falls in the last year	0.9	1.3	2.1	-1.5	-0.6	-0.6	-1.4	-1.1	-1.4	-1.2	-0.6	-1.3
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	4.3	-1.4	-2.1	-1.6	0.3	-1.4	-0.7	0.6	-0.9	0.2
Medication: Paracetamol	0.9	1.4	2.1	1.0	0.5	1.2	1.3	1.1	1.3	1.3	1.5	1.3
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	7.5	-1.6	-0.5	-0.7	-1.4	-0.5	-1.0	-0.9	-2.7	-0.7
Arm fat-free mass (right)	0.9	4.7	19.7	-0.7	-2.8	-4.4	-1.4	-2.2	-1.1	-1.6	-1.4	-1.2
Wheeze or whistling in the chest in last year	0.9	1.6	2.6	-1.0	-0.6	-1.2	-1.6	-1.5	-1.2	-1.6	-1.0	-1.5
Neck or shoulder pain in last month	0.9	1.3	2.4	-1.5	-1.0	-1.1	-0.4	-1.5	-1.4	-0.5	-1.0	-1.2
Leg fat-free mass (right)	0.9	5.0	17.9	-0.9	-3.1	-4.2	-1.6	-2.3	-1.2	-1.6	-1.4	-1.5
Long-standing illness, disability or infirmity	0.9	1.4	4.9	1.4	-0.8	0.8	0.7	2.2	1.5	0.8	-0.5	1.1
Leg fat percentage (left)	0.9	3.2	8.3	1.5	-0.1	0.8	2.2	1.8	2.0	2.3	0.5	2.9
Irritability	0.9	1.5	6.2	0.5	-1.7	-0.8	-1.1	1.0	0.0	-1.1	-2.5	-0.5
Arm predicted mass (left)	0.9	4.4	21.2	-0.8	-2.9	-4.6	-1.0	-2.2	-0.9	-1.1	-1.1	-0.8
Alzheimer’s Disease (including proxy)	0.8	1.2	2.1	-0.9	-0.5	-1.1	-1.0	-1.2	-1.4	-1.2	-0.7	-1.3
Reaction Time	0.8	1.6	2.7	-1.6	-0.8	-0.3	-1.6	-1.0	-1.3	-1.2	-1.5	-1.4
Pack years adult smoking proportion	0.8	1.3	2.9	-0.6	-0.6	-1.6	-1.1	-0.9	-0.6	-1.0	-1.7	-1.3
Leg fat-free mass (left)	0.8	4.4	16.1	-0.7	-3.1	-4.0	-1.6	-1.9	-0.9	-1.5	-1.5	-1.3
Maternal smoking around birth	0.8	1.1	4.1	0.8	0.9	0.9	1.0	0.3	0.8	0.9	2.0	1.0
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.6	-0.8	-0.2	-0.6	-0.9	-0.9	-1.2	-1.1	-0.9	-1.3
Impedance of arm (right)	0.8	3.7	17.8	0.4	2.3	4.2	0.8	1.9	1.0	1.3	1.2	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.0	1.2	1.0	0.8	1.4	0.9	1.1	1.1	0.9	1.4
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.2	0.2	0.8	1.5	1.4	0.4	0.2	1.1	1.1	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	4.0	-0.3	-2.0	-1.5	-0.6	-0.3	-0.3	-0.5	-1.0	-0.3
Ever had bowel cancer screening	0.8	1.0	2.0	-1.4	0.5	0.3	-0.9	-0.8	-1.4	-1.0	-0.6	-1.1
Friendships satisfaction	0.8	1.0	2.2	-0.7	-0.5	-0.8	-0.9	-0.9	-0.9	-1.0	-1.3	-1.5
Basal metabolic rate	0.8	4.6	19.6	-0.8	-3.1	-4.4	-1.5	-2.1	-0.9	-1.4	-1.4	-1.0
Arm fat-free mass (left)	0.8	4.3	19.8	-0.8	-2.7	-4.4	-1.1	-2.3	-1.0	-1.2	-1.1	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	2.6	-0.6	-1.3	-1.6	-1.1	-0.7	-0.7	-1.0	-0.9	-0.9
Impedance of whole body	0.8	4.0	19.2	0.3	2.9	4.4	1.0	1.7	0.7	1.3	1.1	1.2
Worry (Nagel 2018)	0.7	1.4	5.4	1.0	0.8	2.0	1.2	2.3	0.0	0.0	0.4	0.0
Breast Cancer	0.7	1.8	2.8	1.1	1.7	1.2	1.1	1.1	1.5	1.3	1.3	1.5
Ovarian Cancer	0.7	1.0	2.0	0.6	0.3	1.2	1.4	0.3	0.8	1.3	1.0	1.1
Mean Putamen Volume	0.7	0.8	3.1	1.2	0.5	0.9	1.1	0.7	0.0	0.0	1.8	0.0
Rheumatoid Arthritis	0.7	1.0	3.8	-1.5	-0.1	-0.7	-1.5	0.0	0.0	0.0	-1.9	0.0
Smoking Status	0.7	1.7	3.4	1.7	-0.4	0.1	1.2	0.8	1.8	1.3	1.6	1.6
Medication for hormone replacement therapy	0.7	0.8	1.6	-1.3	-0.8	-0.8	-0.3	-1.2	-1.3	-0.4	-0.8	-0.8
Diabetes (father)	0.7	0.8	2.9	-0.8	0.3	-0.7	-0.6	-0.4	-1.0	-0.9	-1.7	-0.9
Medication: Atenolol	0.7	0.9	2.1	-0.7	-1.4	-1.1	-0.8	-1.0	-0.6	-0.8	-1.1	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.4	0.7	1.1	1.4	0.6	1.5	1.2	0.9	-0.4	1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.5	5.3	-1.5	-0.3	-1.6	-0.3	-2.3	-1.5	-0.6	-0.5	-1.0
Depression (self-reported)	0.7	0.8	2.3	0.8	0.6	1.3	0.7	1.5	0.8	0.6	-0.5	0.9
Prospective memory result	0.7	0.9	1.7	-0.9	-0.5	-1.1	-0.8	-1.3	-1.2	-1.0	0.3	-0.9
Blood clot in the leg (DVT)	0.7	0.9	2.7	-0.7	-1.1	-1.6	-1.0	-0.8	-0.7	-0.9	-0.6	-0.8
Health satisfaction	0.7	0.9	2.6	-0.4	-1.5	-0.4	-0.9	0.1	-0.6	-0.9	-1.6	-0.9
Medication: Omeprazole	0.7	0.8	2.0	-1.3	-1.4	-0.6	-0.4	-0.9	-0.8	-0.1	-1.2	-0.4
Heart disease (mother)	0.7	0.9	1.8	0.5	-1.0	-0.3	1.0	0.5	1.2	1.2	-0.9	1.3
Knee pain experienced in last month	0.7	1.1	3.8	-0.9	-1.9	-0.9	-0.3	-0.7	-0.7	-0.3	-1.8	-0.5
Hypertension (Self-reported)	0.7	1.9	5.1	-0.8	-1.3	-1.2	-1.6	-0.8	-0.9	-1.4	-2.2	-1.5
Smoking status: Previous	0.7	1.0	2.0	1.4	1.3	0.8	0.3	1.4	1.0	0.1	1.2	0.6
Illnesses of father: None of the above (group 1)	0.7	0.9	2.3	-0.0	-0.1	1.0	1.3	0.6	0.7	1.5	-0.3	1.4
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.6	1.1	-0.0	0.3	0.7	0.9	1.3	0.9	1.1	1.0
Medication: Bendroflumethiazide	0.7	1.0	2.0	-0.6	-0.8	-0.6	-1.2	-0.7	-1.1	-1.3	-1.0	-1.4
Myopia	0.7	1.0	4.8	-1.1	-1.1	-0.6	-0.4	-0.5	-0.7	-0.3	-2.2	-0.6
Vascular/heart problems diagnosed by doctor	0.7	1.9	5.5	0.7	1.2	1.4	1.5	0.9	0.8	1.3	2.3	1.4
Pain experienced in last month	0.7	1.1	2.2	1.1	1.4	1.5	0.5	1.0	0.8	0.4	1.4	0.6
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.5	0.2	0.4	1.6	0.5	1.0	0.5	0.6	-0.6	0.7
Supplements: Zinc	0.6	0.7	1.8	-1.3	0.4	0.9	0.8	-0.5	-0.2	1.2	-0.1	0.9
Hand grip strength (right)	0.6	1.7	3.7	1.9	1.2	-0.3	1.0	0.8	1.7	0.9	1.7	1.2
Pain all over the body in last month	0.6	0.6	2.0	-0.8	-0.6	-0.3	0.5	-0.2	0.4	1.1	-1.4	0.9
Arm fat percentage (right)	0.6	2.4	5.7	1.2	-1.0	0.3	1.6	1.7	1.9	2.0	0.2	2.4
Hair/balding pattern: Pattern 3	0.6	0.9	1.9	0.3	0.4	0.4	1.1	0.5	0.9	1.4	1.4	1.2
Impedance of arm (left)	0.6	2.9	15.3	0.4	2.2	3.9	0.4	1.7	0.7	0.7	1.0	0.7
Standing height	0.6	5.7	12.3	-1.6	-2.0	-3.5	-2.7	-2.9	-1.9	-2.5	-1.3	-2.2
Birth weight	0.6	1.3	2.9	-0.1	-1.3	-1.6	-1.5	-0.4	-0.8	-1.7	-0.7	-1.1
Body fat percentage	0.6	2.5	6.6	1.2	-0.6	0.8	1.8	1.6	1.8	2.1	0.1	2.6
Age at first live birth	0.6	1.1	4.2	2.0	0.5	0.3	-0.0	1.7	1.3	-0.2	0.6	0.4
Medication: Seretide 50 evohaler	0.6	0.7	1.4	-0.5	-0.1	-0.9	-1.0	-0.8	-0.9	-1.2	-0.7	-0.8
Had major operations	0.6	0.7	1.9	-1.4	0.1	-0.3	-0.4	-1.0	-1.1	-0.3	-1.2	-0.6
Back pain experienced in last month	0.6	0.8	2.7	-1.0	-0.8	-1.6	-0.4	-0.9	-0.9	-0.4	-0.8	-0.7
High cholesterol (Self-reported)	0.6	1.1	2.2	1.3	-0.3	0.9	0.7	1.4	1.5	1.1	0.6	0.9
HDL Cholesterol	0.5	0.8	6.6	1.0	2.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Vitamin and mineral supplements	0.5	0.7	3.7	1.9	0.2	-0.1	0.4	1.0	1.0	-0.3	0.3	0.1
Trunk fat percentage	0.5	2.1	5.7	1.1	-0.8	0.8	1.6	1.4	1.7	1.9	0.1	2.4
Current tobacco smoking	0.5	0.8	2.9	-0.3	-1.7	-1.5	-0.2	-1.1	0.1	0.3	0.4	0.3
Fed-up feelings	0.5	0.9	1.9	0.5	0.2	1.3	1.0	0.8	1.1	1.3	0.2	1.4
Taking other prescription medications	0.5	0.7	2.5	-1.6	-0.3	-0.5	0.1	-1.3	-1.0	0.2	-1.0	-0.3
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.3	-1.1	1.0	0.2	0.2	-0.8	-1.0	-0.1	-0.6	-0.4
Supplements: Glucosamine	0.5	0.6	1.3	0.8	1.0	1.0	0.8	1.2	0.6	0.6	0.1	0.6
Forced vital capacity (FVC)	0.5	2.0	4.8	-0.4	0.6	-1.4	-1.9	-1.4	-1.2	-2.2	0.7	-1.9
Heart attack	0.5	0.7	2.3	-0.2	0.0	0.1	1.4	-0.6	0.5	1.5	-0.4	1.1
Allergy	0.5	1.1	2.4	1.0	-0.2	0.7	1.0	1.2	1.0	1.1	1.6	1.1
Medication: Ramipril	0.5	0.6	2.3	-0.7	-0.6	0.1	-0.9	-0.1	-0.7	-0.6	-1.5	-0.8
Fluid intelligence score	0.5	1.1	2.1	0.7	0.0	1.4	1.1	0.7	1.3	1.5	0.2	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.1	-0.9	-1.1	-0.8	0.7	-1.0	-0.1	0.8	-1.4	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.8	0.4	0.1	-0.3	0.6	0.2	0.7	0.7	1.7	1.0
Medication: Ibuprofen	0.5	0.5	2.8	0.2	0.3	-0.5	0.7	-0.2	0.4	0.7	1.7	0.8
Medication: Allopurinol	0.5	0.6	2.7	0.1	0.6	0.3	0.9	-0.1	0.5	1.0	1.6	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.1	0.4	0.1	1.1	0.7	0.9	0.9	1.1	0.0	0.8
Illnesses of father: Heart disease	0.5	0.8	1.4	-0.8	-0.4	-0.8	-1.2	-0.9	-0.9	-1.1	-0.5	-0.9
Illnesses of siblings: Diabetes	0.5	0.6	1.9	-1.4	0.6	0.4	0.2	-1.1	-0.9	0.2	-0.8	-0.2
Arm fat percentage (left)	0.5	1.9	4.4	1.2	-1.1	0.1	1.4	1.6	1.7	1.7	-0.2	2.1
Eye problems/disorders: Cataract	0.5	0.6	2.8	1.0	1.7	0.3	0.2	0.3	0.4	-0.2	1.2	0.1
Medication: Gliclazide	0.5	0.6	1.8	-0.9	1.3	0.8	0.2	-0.8	-0.8	-0.0	0.8	-0.1
Smoking status: Current	0.5	0.7	2.9	-0.1	-1.7	-1.2	0.1	-0.8	0.5	0.6	0.8	0.7
Miserableness	0.5	0.8	2.6	0.7	-0.4	-0.4	-1.4	0.6	-0.3	-1.6	0.1	-1.2
Medication: Paracetamol	0.5	0.8	1.2	0.6	0.6	0.8	1.0	0.8	1.0	1.1	0.9	1.0
Ever smoked	0.5	0.8	2.2	1.2	-0.4	-0.2	0.1	1.0	1.1	0.3	1.5	1.0
Fractured/broken bones in last 5 years	0.5	0.6	1.0	-0.7	0.6	-0.5	-0.8	-1.0	-0.9	-0.8	-0.2	-1.0
Pack years of smoking	0.5	0.7	2.1	-0.2	-0.5	-1.3	-0.8	-0.5	-0.3	-0.8	-1.4	-1.0
Bipolar Disorder (2018)	0.4	0.7	2.8	1.7	0.6	0.1	1.5	0.0	0.0	0.0	0.8	0.0
Crohns Disease (2017)	0.4	0.9	2.2	-1.5	0.7	0.3	-0.3	-1.1	-1.3	-0.2	1.3	-0.6
Irritable Bowel Disease (IBD)	0.4	0.8	4.1	-0.9	0.9	0.9	0.3	-0.7	-0.6	0.4	2.0	-0.0
Crohns Disease (2012)	0.4	0.7	3.5	1.1	0.7	0.9	0.8	0.0	0.0	0.0	1.9	0.0
Fasting Glucose	0.4	0.4	2.2	1.5	0.2	-0.6	0.3	0.7	0.7	0.0	-0.4	0.3
Hypothyroidism (self reported)	0.4	0.8	3.2	-1.2	0.4	-0.3	-1.3	-0.1	-0.6	-0.8	-1.8	-0.5
Neuroticism	0.4	1.1	4.2	0.8	1.0	2.0	0.6	1.7	0.4	0.2	0.2	0.6
Medication: Co-codamol	0.4	0.4	2.5	-0.6	-0.8	-0.3	-0.1	0.1	-0.3	-0.0	-1.6	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.7	-1.1	-0.6	0.3	-0.8	-0.2	-0.8	-0.5	-1.3	-0.5
Multivitamins +/- minerals	0.4	0.5	2.6	-1.6	-0.7	0.0	-0.1	-0.8	-0.6	0.5	-0.5	0.1
Nervous feelings	0.4	0.7	1.8	1.0	0.8	1.0	0.5	1.4	0.7	0.3	0.4	0.7
Arm fat mass (right)	0.4	1.5	3.2	0.8	-1.8	-1.2	1.1	0.7	1.2	1.3	-0.4	1.7
Peak expiratory flow (PEF)	0.4	0.9	3.4	-0.3	-1.0	-1.8	-0.5	-1.7	-0.4	-0.6	0.1	-0.5
Loud music exposure frequency	0.4	0.5	1.8	0.9	0.8	0.6	-0.5	1.3	0.4	-0.5	0.1	-0.1
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.2	1.0	0.8	0.4	0.8	0.9	0.6	0.4	1.5	0.7
Forced vital capacity (FVC), Best measure	0.4	1.5	3.0	-0.5	1.0	-0.8	-1.4	-1.2	-1.2	-1.7	1.0	-1.7
Exposure to tobacco smoke outside home	0.4	0.5	1.4	-0.1	-0.5	0.5	0.9	0.6	0.6	1.2	-0.1	1.0
Worry too long after embarrassment	0.4	0.6	2.2	0.6	1.1	1.5	0.7	1.2	0.2	0.2	0.3	0.1
Eye problems/disorders: None of the above	0.4	0.4	1.3	0.3	-1.1	-0.6	0.8	-0.0	0.5	0.8	0.2	0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.5	0.5	-0.5	-0.5	0.9	0.2	0.8	0.9	-0.0	1.2
Diabetes diagnosed by doctor	0.4	0.6	1.5	-1.0	-0.9	-0.6	-0.5	-0.8	-0.8	-0.3	-1.2	-0.6
Unable to work because of sickness or disability	0.4	0.5	1.6	-1.2	-0.6	-0.3	-0.5	-0.7	-0.5	0.0	-1.3	-0.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.3	-0.7	-0.2	-0.4	0.9	-1.1	-0.0	1.1	-0.8	0.6
Neuroticism (Nagel 2018)	0.3	0.6	3.1	0.9	-0.1	1.2	0.5	1.8	0.0	0.0	-0.2	0.0
Alzheimer’s Disease (in father)	0.3	0.3	0.6	-0.7	-0.6	-0.6	-0.3	-0.8	-0.6	-0.2	-0.2	-0.4
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.3	1.0	0.1	1.1	0.7	0.8	1.2	0.9	0.3	1.1
Neuroticism (2016)	0.3	0.4	0.8	-0.5	0.6	0.2	-0.8	-0.5	-0.8	-0.9	-0.1	-0.7
Triglycerides	0.3	0.5	3.8	-1.1	-1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Systolic Blood Pressure	0.3	1.5	3.9	-0.7	-0.7	-2.0	-1.3	-0.8	-1.0	-1.4	-1.4	-1.3
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.1	-0.8	-0.7	-0.7	-0.3	-0.9	-0.8	-0.3	-1.1	-0.4
Hand grip strength (left)	0.3	0.8	2.4	1.5	0.7	-0.2	0.7	0.6	1.4	0.6	0.8	0.8
Relative age of first facial hair	0.3	0.7	2.6	0.1	0.9	1.6	0.5	0.8	0.6	0.9	0.3	0.9
Qualifications: CSEs or equivalent	0.3	0.5	1.3	1.0	-0.8	-1.1	-0.1	0.7	0.2	-0.4	0.7	-0.3
Sitting height	0.3	2.3	8.8	-0.1	-2.2	-3.0	-1.2	-1.7	-0.3	-1.2	0.2	-0.8
Body mass index (BMI)	0.3	1.3	3.1	0.7	-1.8	-1.5	1.0	0.5	1.0	1.1	-0.3	1.5
Trunk fat mass	0.3	1.3	3.4	0.8	-1.6	-0.6	1.0	0.8	1.3	1.3	-0.4	1.8
Medication: Simvastatin	0.3	0.4	1.3	-0.1	-1.1	0.2	-0.7	0.5	-0.2	-0.6	-1.1	-0.7
Weight	0.3	1.6	7.4	-0.1	-2.4	-2.7	-0.1	-0.7	0.2	0.1	-0.7	0.6
Alcohol intake versus 10 years previously	0.3	0.4	1.3	-0.3	-0.1	0.4	0.7	0.4	0.4	1.2	-0.1	1.1
Father’s age at death	0.3	0.4	1.0	1.0	0.7	0.8	0.1	0.9	0.1	-0.5	0.0	0.1
Worrier / anxious feelings	0.3	0.5	1.7	0.5	0.5	1.3	0.4	1.0	0.5	0.4	0.6	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.8	0.2	-0.8	-0.1	-0.6	-0.0	-0.4	-0.9	-0.4	-0.8
Lung cancer (father)	0.3	0.4	1.4	1.0	-0.0	-0.3	-0.1	1.2	0.8	0.1	0.1	0.4
Length of working week for main job	0.3	0.3	1.0	-0.2	-0.9	0.1	-1.0	0.4	-0.1	-0.6	-0.7	-0.3
Medication: Amlodipine	0.3	0.4	0.8	0.4	-0.4	0.1	0.7	0.7	0.7	0.9	0.3	0.9
Comparative body size at age 10	0.3	0.8	6.3	-0.5	-2.5	-0.0	-0.3	0.5	-0.4	-0.1	-0.5	0.0
Medication for pain relief, constipation, heartburn	0.3	0.5	1.4	-0.5	1.2	0.7	-0.5	-0.2	-0.8	-0.7	-0.7	-0.7
Whole body fat mass	0.3	1.3	3.2	0.8	-1.7	-0.9	1.0	0.7	1.2	1.2	-0.5	1.8
Leg fat mass (right)	0.3	1.3	3.1	0.9	-1.6	-0.9	1.0	0.9	1.2	1.2	-0.4	1.8
Alcohol intake frequency.	0.3	0.8	1.9	-1.3	-1.0	-1.2	-0.0	-1.4	-0.6	0.2	-0.7	-0.3
Overall health rating	0.3	0.7	2.9	-0.5	-1.7	-0.4	0.6	0.3	0.0	0.8	-1.4	0.6
Leg pain on walking	0.3	0.3	0.7	-0.7	-0.9	-0.5	0.4	-0.9	-0.5	0.2	0.5	0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.8	0.7	0.9	0.5	0.6	0.7	0.6	0.3	0.5	0.1
Supplements: Vitamin C	0.3	0.4	1.3	-0.7	0.9	1.1	0.2	0.1	0.1	0.8	0.6	0.4
Commuting to job workplace: Walk	0.3	0.3	0.9	-0.1	-0.0	0.5	-0.9	0.1	-0.3	-0.8	-0.3	-0.9
Medication for cholesterol	0.3	0.5	1.0	-0.8	0.7	1.0	0.5	-0.3	0.2	1.0	0.3	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.7	-0.3	0.7	1.3	0.2	0.3	-0.2	0.1	0.8	0.2
Medication: Aspirin	0.3	0.4	1.3	1.1	-0.4	0.2	0.2	1.1	0.8	0.1	-0.0	0.1
Arm fat mass (left)	0.3	1.4	4.2	0.7	-2.0	-1.6	0.7	0.5	1.1	0.9	-0.5	1.4
Average weekly champagne plus white wine intake	0.3	0.4	1.0	-0.3	0.1	1.0	0.8	-0.3	0.3	1.0	0.5	0.7
Mother’s age at death	0.3	0.3	0.6	0.6	0.8	0.8	0.7	0.2	0.5	0.5	-0.0	0.5
Medication: Blood pressure	0.3	0.5	1.0	0.7	-0.7	-1.0	-0.6	0.1	-0.0	-0.9	-0.7	-0.9
Risk taking	0.3	0.4	0.9	0.3	1.0	0.3	0.8	0.4	0.3	0.7	0.9	0.8
Commuting to job workplace: Cycle	0.3	0.3	1.2	-0.3	0.9	1.1	-0.2	-0.1	-0.5	-0.3	0.3	-0.7
Heart disease (siblings)	0.3	0.3	0.7	-0.7	-0.4	-0.1	-0.4	-0.8	-0.8	-0.5	0.1	-0.8
Leg fat mass (left)	0.3	1.3	3.1	1.0	-1.5	-1.0	1.1	0.8	1.2	1.2	-0.2	1.8
Depression (Nagel 2018)	0.2	0.3	1.8	-0.4	-0.8	-0.2	-0.5	-0.3	0.0	0.0	-1.3	0.0
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.8	1.3	0.8	1.1	0.8	0.9	0.0	0.0	0.5	0.0
Ulcerative Colitis (UC)	0.2	0.4	2.6	0.1	0.5	0.6	0.4	-0.1	0.2	0.4	1.6	0.3
Blood Platelet Count	0.2	1.8	3.4	1.9	-0.2	0.8	1.4	1.8	1.7	1.2	1.0	1.2
Blood Red Count	0.2	1.5	6.2	-0.8	-2.5	-1.0	-1.2	-1.1	-1.0	-1.1	-0.1	-0.9
Blood White Count	0.2	1.2	4.0	-0.5	-2.0	-1.9	-0.3	-0.4	-0.5	-0.3	-1.4	-0.5
BMI	0.2	1.4	5.6	0.3	-2.4	-2.2	0.4	-0.1	0.6	0.5	-0.7	1.1
Height	0.2	4.6	12.5	-2.0	-2.6	-3.3	-1.6	-3.5	-1.4	-1.3	-0.7	-1.1
Cardiovascular Disease	0.2	0.6	1.4	0.2	-0.3	-0.8	-1.2	-0.1	-0.0	-1.1	-1.0	-1.0
Lung FVC	0.2	1.0	2.4	-0.1	1.0	0.2	-1.2	-0.2	-1.0	-1.5	0.9	-1.6
Tanning	0.2	2.2	6.7	1.4	2.6	1.1	1.3	1.1	1.3	1.2	1.4	1.1
Hearing difficulty/problems: Yes	0.2	0.3	1.0	0.2	-0.4	-1.0	-0.5	-0.6	-0.2	-0.7	0.3	-0.5
Medication: Metformin	0.2	0.3	0.6	-0.6	-0.7	0.2	-0.1	-0.4	-0.7	-0.1	-0.8	-0.4
Hayfever, allergic rhinitis or eczema	0.2	0.4	2.1	0.4	1.4	0.7	0.5	0.5	0.4	0.3	0.1	0.3
Waist circumference	0.2	0.8	2.4	0.2	-1.6	-1.6	0.6	-0.1	0.5	0.7	-0.5	1.0
Number of incorrect matches in round	0.2	0.3	0.9	-0.4	-1.0	0.1	-0.5	-0.2	-0.6	-0.5	-0.1	-0.6
Alcohol usually taken with meals	0.2	0.3	0.8	-0.8	0.5	0.2	0.3	-0.7	-0.6	0.2	-0.9	0.0
Hair/balding pattern: Pattern 2	0.2	0.2	0.4	-0.4	-0.3	0.3	-0.6	-0.2	-0.5	-0.6	-0.1	-0.6
Had other major operations	0.2	0.3	1.2	-0.5	-0.4	-0.6	-0.2	-1.1	-0.5	-0.2	0.1	-0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.8	0.3	0.9	0.8	-0.6	0.5	0.1	-0.6	0.5	-0.2
Diabetes (self-reported)	0.2	0.3	0.8	-0.6	-0.1	-0.0	-0.3	-0.5	-0.7	-0.3	-0.9	-0.6
Hip circumference	0.2	1.0	4.5	-0.3	-1.7	-2.1	-0.1	-0.7	-0.2	-0.0	-0.8	0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	2.5	0.5	0.8	-0.6	-0.6	-0.5	-0.1	-0.8	1.6	-0.5
Medication: Cholesterol lowering	0.2	0.3	1.5	-0.5	-0.7	0.2	0.1	-0.2	0.1	0.5	-1.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.2	0.1	0.9	-0.3	-0.5	-0.5	-0.4	-0.8	1.5	-0.7
Tense / ‘highly strung’	0.2	0.4	1.3	-0.0	0.6	0.3	-0.8	0.3	-0.6	-1.1	-0.3	-0.7
Number of full brothers	0.2	0.3	2.1	0.0	0.3	0.1	0.3	-0.4	-0.1	0.3	1.4	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	-0.5	-0.4	-0.3	0.8	-0.5	-0.2	0.6	-0.6	0.4
Number of children fathered	0.2	0.2	0.9	0.9	-0.5	-0.1	0.2	0.6	0.5	0.0	0.3	0.2
Medication: Blood pressure	0.2	0.3	1.1	-0.5	-0.8	-0.4	-0.7	-0.4	-0.1	-0.2	-1.0	-0.3
Suffer from ‘nerves’	0.2	0.3	0.5	-0.3	0.7	0.6	-0.5	0.2	-0.7	-0.7	0.6	-0.3
Age at last live birth	0.2	0.3	0.6	0.6	-0.3	0.4	0.2	0.7	0.8	0.4	-0.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.8	0.4	-0.1	-1.3	-0.9	0.0	0.2	-0.8	-0.4	-0.7
Osteoporosis (self-reported)	0.2	0.2	0.5	-0.5	0.4	0.5	-0.4	0.1	-0.7	-0.4	0.5	-0.4
Osteoarthritis (self-reported)	0.2	0.3	1.2	0.4	-1.1	-0.7	0.3	0.5	0.3	0.1	0.2	0.4
Guilty feelings	0.2	0.3	1.4	0.3	0.8	1.2	0.2	0.7	0.4	0.2	0.3	0.5
Hearing aid user	0.2	0.3	0.8	-0.3	0.6	0.4	0.7	0.0	0.2	0.9	-0.0	0.7
Medication: Atorvastatin	0.2	0.2	0.9	0.3	-0.9	-0.6	0.2	-0.1	0.5	0.6	0.2	0.3
Alcohol drinker status: Never	0.2	0.3	0.9	0.0	0.0	-0.0	0.8	-0.1	0.5	1.0	0.3	0.6
Cholesterol lowering medication	0.2	0.3	2.1	0.4	-1.5	-0.7	-0.0	0.2	0.0	-0.2	0.1	-0.2
Bipolar Disorder or Schizophrenia	0.1	0.2	0.9	0.5	0.3	-0.3	0.9	0.0	0.0	0.0	0.3	0.0
Depressed Affect (Nagel 2018)	0.1	0.2	0.9	0.5	-0.6	0.5	0.1	0.9	0.0	0.0	-0.4	0.0
Body Mass Index (BMI) (2010)	0.1	0.1	0.7	-0.2	-0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.1	0.1	0.8	-0.7	-0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lupus	0.1	0.2	1.5	0.5	0.2	0.1	0.3	0.1	-0.1	0.0	-1.2	0.2
Primary Biliary Cirrhosis	0.1	0.2	0.8	-0.9	0.1	0.3	-0.6	0.0	0.0	0.0	-0.7	0.0
Schizophrenia (2014)	0.1	0.1	0.8	-0.9	-0.2	-0.4	0.0	0.0	0.0	0.0	-0.3	0.0
Ulcerative Colitis	0.1	0.2	1.1	0.0	0.7	1.0	0.0	0.0	0.0	0.0	0.5	0.0
Blood Eosinophil Count	0.1	0.5	2.0	0.3	-0.8	-0.6	-0.7	0.9	0.4	-0.4	-1.4	-0.1
Heel T-Score	0.1	1.1	4.1	0.2	0.2	2.0	1.3	0.7	0.2	0.9	1.3	0.8
Waist Hip Ratio (WHR)	0.1	0.3	1.7	0.1	0.7	0.3	0.5	-0.3	-0.1	0.3	1.3	0.2
Allergy or Eczema	0.1	0.3	0.8	0.5	0.6	0.8	-0.2	0.9	0.4	-0.3	-0.3	-0.1
Hair Pigment	0.1	1.8	8.9	-0.1	-1.8	-3.0	-0.8	-0.8	-0.4	-0.9	-0.9	-0.9
Number of treatments/medications taken	0.1	0.2	0.3	0.0	-0.5	-0.4	0.5	-0.2	0.2	0.5	-0.6	0.2
Systolic blood pressure, automated reading	0.1	0.3	0.9	0.5	-0.4	-0.4	0.2	0.9	0.6	0.3	-0.9	0.5
Angina	0.1	0.1	0.4	-0.0	-0.5	-0.1	-0.0	-0.3	0.6	0.5	-0.3	0.3
Severe depression (siblings)	0.1	0.1	0.5	-0.2	0.3	-0.4	-0.2	-0.7	-0.2	-0.1	0.0	0.0
Townsend deprivation index at recruitment	0.1	0.1	0.3	0.2	-0.1	0.5	-0.4	0.3	0.2	-0.3	0.1	-0.3
Hearing difficulty/problems with background noise	0.1	0.2	0.7	0.9	0.6	0.1	0.1	0.4	0.5	-0.2	0.1	0.2
Neuroticism score	0.1	0.3	0.5	-0.2	0.1	0.5	-0.5	0.5	-0.6	-0.7	-0.7	-0.5
Happiness	0.1	0.1	0.4	0.2	-0.6	0.1	0.5	-0.4	0.1	0.2	-0.1	-0.1
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.3	-0.6	-0.5	0.3	0.5	-0.3	-0.4	0.3	-0.3	0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.6	-0.7	-0.4	0.8	-0.4	-0.2	-0.4	-0.1	-0.2	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.9	-0.1	0.2	0.2	0.2	-0.4	-0.3	-0.0	0.9	0.0
Qualifications: College or University degree	0.1	0.4	2.4	0.6	1.6	0.6	0.3	-0.1	0.1	-0.1	0.8	-0.2
Angina (self-reported)	0.1	0.2	0.6	0.0	-0.5	0.1	0.1	-0.1	0.8	0.7	-0.1	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.7	-0.0	-0.8	0.4	-0.1	0.3	-0.1	-0.1	-0.2	-0.1
Family relationship satisfaction	0.1	0.2	0.4	0.1	0.1	0.6	0.5	-0.1	0.2	0.5	0.6	0.3
Medication: Aspirin	0.1	0.2	0.5	0.7	-0.6	-0.2	0.1	0.7	0.4	-0.1	-0.1	-0.1
Mood swings	0.1	0.1	0.3	0.2	-0.2	0.0	-0.2	0.6	0.1	-0.2	-0.5	0.4
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.0	0.0	1.0	0.4	0.3	0.2	0.1	0.4	0.3	0.2
Mineral and other dietary supplements	0.1	0.1	0.4	0.6	0.4	-0.4	0.0	0.1	0.6	0.1	0.2	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.1	-0.2	1.1	-0.4	0.2	-0.5	-0.7	-0.4	0.4	-0.6
Wears glasses or contact lenses	0.1	0.1	0.4	-0.3	-0.2	0.5	0.6	-0.1	-0.1	0.6	-0.0	0.3
Ever taken oral contraceptive pill	0.1	0.1	0.6	0.0	-0.0	0.2	-0.5	0.1	-0.0	-0.5	-0.8	-0.3
Financial situation satisfaction	0.1	0.1	0.2	0.5	-0.3	0.5	0.3	0.1	-0.0	-0.1	0.0	0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.4	-0.0	-0.3	0.5	-0.6	0.5	-0.1	-0.5	-0.0	-0.3
Diastolic blood pressure, automated reading	0.1	0.3	0.9	0.2	-0.8	-0.9	0.6	-0.0	0.4	0.6	-0.5	0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.4	-0.0	-0.2	0.6	0.4	0.2	0.1	0.5	0.0	0.3
Schizophrenia (2018)	0.0	0.1	0.3	-0.6	-0.0	-0.4	-0.0	0.0	0.0	0.0	-0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.2	0.5	-0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	0.0	-0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Chronotype (morning person)	0.0	0.1	0.3	0.2	-0.5	-0.0	0.1	0.2	0.2	0.1	-0.5	-0.0
Frequency of depressed mood in last 2 weeks	0.0	0.1	0.3	-0.0	-0.3	-0.2	-0.2	0.2	0.2	-0.0	-0.6	0.2
Noisy workplace	0.0	0.0	0.2	-0.1	-0.2	-0.1	0.1	-0.2	0.1	0.2	0.4	0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.4	0.2	0.1	0.6	-0.2	0.6	0.1	-0.1	0.1	0.3

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