[Hub]/) : Traits : Height : ← →

chr15:88,317,958-92,135,418

Best TWAS P=2.14e-72 · Best GWAS P=5.66e-203 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FURIN	0.12	0.14	lasso	2	0.13	1.2e-15	5.89	-5.8	4.9e-09	-0.08	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	IQGAP1	0.19	0.21	lasso	5	0.20	1.7e-24	5.53	5.7	1.6e-08	0.03	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	RLBP1	0.27	0.19	enet	20	0.24	1.5e-29	-3.63	-5.2	2.4e-07	-0.07	1.00	0.00	FALSE
4	CommonMind	Brain Pre-frontal Cortex	ZNF774	0.20	0.08	lasso	7	0.14	1.8e-16	6.59	-5.7	1.2e-08	-0.01	0.95	0.05	FALSE
5	GTEx	Adipose Subcutaneous	POLG	0.21	0.14	lasso	7	0.19	2.2e-15	-6.21	-6.6	5.5e-11	-0.12	1.00	0.00	FALSE
6	GTEx	Adipose Visceral Omentum	POLG	0.10	0.10	lasso	2	0.06	3.9e-04	-6.10	-6.1	8.8e-10	-0.12	0.85	0.01	FALSE
7	GTEx	Artery Aorta	POLG	0.31	0.28	lasso	6	0.29	2.7e-16	-5.99	-6.2	6.4e-10	-0.12	1.00	0.00	FALSE
8	GTEx	Artery Aorta	MFGE8	0.34	0.07	lasso	8	0.11	1.7e-06	-0.21	6.2	4.5e-10	-0.05	0.92	0.00	TRUE
9	GTEx	Artery Aorta	ZNF774	0.22	0.24	enet	16	0.23	7.6e-13	6.59	6.5	8.9e-11	0.06	0.75	0.25	FALSE
10	GTEx	Artery Coronary	POLG	0.27	0.02	enet	2	0.01	1.3e-01	-6.09	-6.1	1.0e-09	-0.12	0.09	0.09	FALSE
11	GTEx	Artery Tibial	POLG	0.19	0.19	lasso	4	0.19	1.4e-14	-6.22	-6.4	1.6e-10	-0.13	1.00	0.00	FALSE
12	GTEx	Brain Cortex	HAPLN3	0.40	-0.01	lasso	5	-0.01	6.0e-01	-4.02	-13.4	9.8e-41	-0.04	0.05	0.09	TRUE
13	GTEx	Breast Mammary Tissue	POLG	0.17	0.18	enet	10	0.16	1.5e-08	-6.15	-6.1	1.1e-09	-0.12	1.00	0.00	FALSE
14	GTEx	Breast Mammary Tissue (Male)	POLG	0.12	0.12	lasso	2	0.08	5.9e-03	-6.01	-6.0	1.6e-09	-0.12	0.08	0.08	FALSE
15	GTEx	Breast Mammary Tissue (Female)	POLG	0.22	0.15	enet	13	0.16	1.9e-05	-6.12	-6.0	2.6e-09	-0.12	0.73	0.01	FALSE
16	GTEx	Cells Transformed fibroblasts	IQGAP1	0.13	0.06	enet	19	0.11	9.2e-09	5.73	6.3	2.5e-10	0.05	0.32	0.53	FALSE
17	GTEx	Cells Transformed fibroblasts	FES	0.28	0.17	enet	21	0.20	2.8e-15	-4.08	5.3	9.3e-08	0.10	1.00	0.00	FALSE
18	GTEx	Colon Sigmoid	POLG	0.16	0.12	lasso	4	0.15	6.7e-06	-6.14	-6.2	7.5e-10	-0.12	0.86	0.02	FALSE
19	GTEx	Colon Transverse	MFGE8	0.17	0.05	lasso	2	0.05	3.0e-03	-8.33	8.5	2.3e-17	-0.01	0.23	0.09	FALSE
20	GTEx	Colon Transverse	PEX11A	0.21	0.15	lasso	2	0.12	2.5e-06	5.45	5.6	1.8e-08	0.03	0.89	0.01	FALSE
21	GTEx	Esophagus Gastroesophageal Junction	POLG	0.29	0.28	lasso	3	0.25	1.1e-09	-6.14	-6.1	9.7e-10	-0.12	1.00	0.00	FALSE
22	GTEx	Esophagus Gastroesophageal Junction	ZNF774	0.16	0.16	lasso	2	0.11	7.8e-05	7.69	7.8	5.5e-15	0.05	0.12	0.76	TRUE
23	GTEx	Esophagus Mucosa	CRTC3	0.08	0.07	enet	7	0.04	6.1e-04	7.33	-7.2	8.5e-13	-0.04	0.25	0.70	FALSE
24	GTEx	Esophagus Muscularis	POLG	0.16	0.11	lasso	5	0.12	1.2e-07	-6.15	-6.3	2.2e-10	-0.13	1.00	0.00	FALSE
25	GTEx	Esophagus Muscularis	ZNF774	0.18	0.19	lasso	5	0.18	4.1e-11	6.47	-6.5	9.9e-11	-0.06	0.88	0.12	FALSE
26	GTEx	Heart Left Ventricle	MFGE8	0.11	0.03	lasso	6	0.05	1.8e-03	-8.10	8.7	3.2e-18	0.03	0.11	0.04	FALSE
27	GTEx	Liver	ANPEP	0.26	0.00	lasso	8	0.02	8.6e-02	4.99	-5.3	1.1e-07	-0.05	0.12	0.19	FALSE
28	GTEx	Lung	MFGE8	0.12	0.04	lasso	5	0.06	1.4e-05	-10.68	8.6	7.0e-18	-0.03	0.78	0.01	FALSE
29	GTEx	Lung	ZNF774	0.06	0.09	enet	6	0.03	1.5e-03	7.69	7.0	2.0e-12	0.04	0.15	0.81	FALSE
30	GTEx	Muscle Skeletal	POLG	0.07	0.00	lasso	3	0.01	6.0e-02	-6.15	-6.3	3.4e-10	-0.12	0.82	0.01	TRUE
31	GTEx	Muscle Skeletal	DET1	0.08	0.08	lasso	3	0.08	3.6e-08	5.73	5.8	5.3e-09	-0.02	1.00	0.00	FALSE
32	GTEx	Nerve Tibial	POLG	0.19	0.20	lasso	5	0.19	1.0e-13	-5.99	-6.1	1.0e-09	-0.13	1.00	0.00	FALSE
33	GTEx	Nerve Tibial	MFGE8	0.21	0.07	enet	17	0.12	1.0e-08	-6.85	10.4	3.9e-25	0.01	0.98	0.00	FALSE
34	GTEx	Pituitary	IQGAP1	0.60	0.45	enet	26	0.52	3.7e-15	3.62	5.3	1.4e-07	0.01	1.00	0.00	FALSE
35	GTEx	Skin Not Sun Exposed Suprapubic	POLG	0.10	0.11	lasso	5	0.09	1.8e-05	-6.22	-6.2	4.6e-10	-0.13	0.92	0.01	FALSE
36	GTEx	Skin Sun Exposed Lower leg	POLG	0.10	0.13	lasso	3	0.12	2.8e-10	-6.15	-6.2	5.8e-10	-0.13	1.00	0.00	FALSE
37	GTEx	Skin Sun Exposed Lower leg	CRTC3	0.10	0.08	lasso	3	0.05	7.5e-05	7.56	-8.1	3.9e-16	-0.07	0.26	0.73	TRUE
38	GTEx	Spleen	MFGE8	0.47	0.27	lasso	5	0.25	4.4e-07	-4.40	-7.2	5.6e-13	-0.01	0.48	0.03	TRUE
39	GTEx	Stomach	IQGAP1	0.21	0.14	enet	17	0.18	8.3e-09	5.57	6.1	8.5e-10	0.04	0.54	0.46	FALSE
40	GTEx	Stomach	MRPS11	0.35	-0.01	lasso	11	0.01	1.1e-01	-8.91	-9.3	1.8e-20	0.01	0.07	0.06	TRUE
41	GTEx	Testis	FANCI	0.19	0.04	enet	21	0.09	1.3e-04	-6.07	-12.8	2.1e-37	-0.08	0.21	0.04	FALSE
42	GTEx	Testis	PLIN1	0.14	0.09	lasso	5	0.08	1.4e-04	5.45	-5.5	2.9e-08	-0.04	0.31	0.21	FALSE
43	GTEx	Testis	ISG20	0.39	0.23	enet	41	0.26	4.0e-12	6.14	-6.5	1.1e-10	0.00	0.99	0.00	FALSE
44	GTEx	Testis	ZNF774	0.13	0.09	lasso	4	0.08	1.5e-04	5.57	-5.6	1.9e-08	-0.03	0.40	0.09	FALSE
45	GTEx	Thyroid	POLG	0.07	0.03	lasso	5	0.03	3.8e-03	-6.16	-6.2	4.0e-10	-0.12	0.40	0.03	FALSE
46	GTEx	Whole Blood	MFGE8	0.12	0.14	lasso	4	0.13	9.3e-12	-8.91	-9.8	1.1e-22	-0.01	1.00	0.00	FALSE
47	METSIM	Adipose	FES	0.08	0.06	lasso	3	0.05	6.8e-08	-3.85	5.3	1.1e-07	0.08	1.00	0.00	FALSE
48	METSIM	Adipose	IQGAP1	0.11	0.08	enet	32	0.12	3.9e-17	7.87	7.1	9.4e-13	0.04	0.20	0.80	FALSE
49	METSIM	Adipose	POLG	0.04	0.02	blup	469	0.03	4.9e-05	-6.11	-11.0	5.8e-28	-0.08	0.96	0.00	TRUE
50	NTR	Blood	IQGAP1	0.03	0.04	enet	10	0.04	1.5e-12	7.57	7.7	1.2e-14	0.06	0.25	0.75	FALSE
51	NTR	Blood	ZNF710	0.02	0.00	bslmm	443	0.01	1.5e-04	-6.67	-6.5	1.1e-10	0.05	0.14	0.02	TRUE
52	YFS	Blood	BLM	0.41	0.35	enet	13	0.36	2.7e-122	7.22	7.5	7.5e-14	-0.01	0.76	0.24	FALSE
53	YFS	Blood	CRTC3	0.02	0.01	blup	503	0.01	4.2e-05	7.84	-6.8	1.2e-11	-0.06	0.21	0.79	FALSE
54	YFS	Blood	DET1	0.17	0.20	lasso	4	0.20	1.4e-62	-8.06	-8.1	5.0e-16	0.02	1.00	0.00	TRUE
55	YFS	Blood	FES	0.31	0.11	enet	77	0.22	1.2e-68	-4.08	6.7	2.1e-11	0.08	1.00	0.00	FALSE
56	YFS	Blood	FURIN	0.11	0.03	enet	37	0.06	8.3e-19	5.89	8.9	7.9e-19	0.08	1.00	0.00	TRUE
57	YFS	Blood	IQGAP1	0.18	0.17	enet	46	0.20	5.8e-65	5.62	7.1	1.6e-12	0.06	1.00	0.00	FALSE
58	YFS	Blood	MRPS11	0.03	0.00	bslmm	436	0.01	9.6e-05	-1.11	-10.1	6.8e-24	0.07	0.13	0.05	FALSE
59	YFS	Blood	PEX11A	0.04	0.02	lasso	2	0.02	1.1e-06	5.45	5.4	6.8e-08	0.03	1.00	0.00	FALSE
60	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IQGAP1	0.04	0.03	lasso	4	0.02	6.5e-03	7.57	7.5	5.0e-14	0.06	0.02	0.85	FALSE
61	The Cancer Genome Atlas	Breast Invasive Carcinoma	DET1	0.02	0.02	blup	48	0.01	8.6e-04	6.62	-6.7	2.2e-11	0.01	0.07	0.84	TRUE
62	The Cancer Genome Atlas	Breast Invasive Carcinoma	FES	0.06	0.05	blup	46	0.07	7.4e-14	-4.08	5.5	4.3e-08	0.09	1.00	0.00	FALSE
63	The Cancer Genome Atlas	Breast Invasive Carcinoma	IQGAP1	0.03	0.02	blup	94	0.02	6.5e-05	5.45	5.8	5.3e-09	0.03	0.09	0.88	FALSE
64	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	IQGAP1	0.15	0.09	lasso	4	0.12	1.9e-06	7.54	6.9	6.7e-12	0.07	0.01	0.98	FALSE
65	The Cancer Genome Atlas	Colon Adenocarcinoma	HAPLN3	0.14	0.04	lasso	4	0.08	1.7e-05	2.63	-18.0	2.1e-72	0.43	0.05	0.58	TRUE
66	The Cancer Genome Atlas	Colon Adenocarcinoma	MFGE8	0.09	0.04	blup	73	0.03	8.9e-03	-6.85	6.3	2.2e-10	-0.10	0.08	0.03	FALSE
67	The Cancer Genome Atlas	Esophageal Carcinoma	MFGE8	0.23	0.14	lasso	3	0.08	2.0e-03	-6.86	5.7	1.2e-08	0.02	0.28	0.13	FALSE
68	The Cancer Genome Atlas	Glioblastoma Multiforme	IQGAP1	0.10	-0.01	blup	95	0.02	1.0e-01	2.68	5.4	6.7e-08	0.03	0.04	0.55	FALSE
69	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IQGAP1	0.15	0.05	enet	10	0.08	2.5e-09	5.53	5.8	6.4e-09	0.07	0.03	0.97	FALSE
70	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ZNF774	0.04	0.02	blup	57	0.02	1.2e-03	4.32	-5.7	1.3e-08	-0.04	0.04	0.79	TRUE
71	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C15orf42	0.02	0.01	lasso	2	0.02	9.7e-04	8.95	9.0	2.0e-19	-0.01	0.01	0.89	FALSE
72	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IQGAP1	0.07	0.06	blup	94	0.07	9.5e-09	7.76	6.4	1.9e-10	0.04	0.02	0.98	FALSE
73	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF774	0.04	0.00	enet	7	0.01	5.1e-02	7.69	6.3	2.7e-10	0.06	0.00	0.92	TRUE
74	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IQGAP1	0.06	0.05	blup	94	0.04	2.6e-03	3.15	5.7	1.3e-08	0.03	0.10	0.64	FALSE
75	The Cancer Genome Atlas	Brain Lower Grade Glioma	C15orf42	0.07	0.07	lasso	5	0.06	9.0e-08	8.72	8.7	2.7e-18	-0.02	0.01	0.99	TRUE
76	The Cancer Genome Atlas	Brain Lower Grade Glioma	CRTC3	0.03	0.01	blup	78	0.01	4.2e-02	5.83	-6.7	2.2e-11	-0.04	0.02	0.60	FALSE
77	The Cancer Genome Atlas	Brain Lower Grade Glioma	MFGE8	0.06	0.02	blup	73	0.03	7.1e-05	-4.40	-8.0	1.2e-15	-0.04	0.38	0.02	TRUE
78	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF774	0.06	0.06	lasso	3	0.04	1.2e-05	7.69	-7.5	4.6e-14	-0.05	0.00	1.00	FALSE
79	The Cancer Genome Atlas	Lung Adenocarcinoma	IQGAP1	0.06	0.04	blup	94	0.03	5.8e-05	6.76	7.4	1.1e-13	0.07	0.07	0.92	FALSE
80	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IQGAP1	0.02	0.02	blup	94	0.02	6.2e-03	5.54	5.2	1.9e-07	0.03	0.08	0.33	FALSE
81	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C15orf42	0.09	0.08	lasso	1	0.08	3.2e-04	9.29	9.3	1.5e-20	-0.03	0.00	0.96	FALSE
82	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DET1	0.06	0.09	lasso	3	0.08	2.4e-04	5.73	-5.8	8.6e-09	0.03	0.10	0.20	FALSE
83	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	MFGE8	0.18	0.01	lasso	4	0.04	9.9e-03	11.74	-16.7	1.4e-62	-0.01	0.04	0.05	TRUE
84	The Cancer Genome Atlas	Prostate Adenocarcinoma	IQGAP1	0.11	0.03	enet	8	0.06	1.4e-06	5.53	6.1	1.0e-09	0.10	0.07	0.92	FALSE
85	The Cancer Genome Atlas	Stomach Adenocarcinoma	FES	0.04	0.01	blup	46	0.02	1.7e-02	-4.52	5.9	3.9e-09	0.09	0.02	0.06	TRUE
86	The Cancer Genome Atlas	Stomach Adenocarcinoma	IQGAP1	0.12	0.07	lasso	4	0.07	1.4e-05	7.87	7.4	1.7e-13	0.04	0.01	0.99	FALSE
87	The Cancer Genome Atlas	Testicular Germ Cell Tumors	IQGAP1	0.14	0.07	lasso	2	0.08	8.5e-04	5.61	5.9	4.2e-09	0.05	0.03	0.77	FALSE
88	The Cancer Genome Atlas	Thyroid Carcinoma	IQGAP1	0.06	0.04	blup	95	0.08	3.0e-08	5.57	5.9	2.8e-09	0.04	0.03	0.97	FALSE