Hub : Genes

ANPEP

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Liver 0.2620 0.1100 4.5e-03 -0.004 NA 0.010 NA 0.021 4.3e-01 NA 1.7e-01 NA 8.6e-02
2 GTEx Lung 0.2091 0.0529 1.3e-05 0.217 NA 0.194 NA 0.213 1.5e-16 NA 8.8e-15 NA 3.3e-16
3 GTEx Muscle Skeletal 0.1892 0.0573 2.3e-04 0.081 NA 0.065 NA 0.073 2.5e-08 NA 5.7e-07 NA 1.2e-07
4 METSIM Adipose 0.0831 0.0217 3.6e-07 0.099 0.064 0.086 0.087 0.093 1.4e-14 7.5e-10 8.4e-13 5.1e-13 1.0e-13
5 NTR Blood 0.1285 0.0236 0.0e+00 0.103 0.089 0.107 0.107 0.105 1.9e-31 4.5e-27 1.1e-32 1.4e-32 5.2e-32
6 YFS Blood 0.5513 0.0333 0.0e+00 0.397 0.477 0.494 0.491 0.490 4.5e-141 3.6e-180 3.1e-189 1.6e-187 7.4e-187
7 TCGA Bladder Urothelial Carcinoma 0.0680 0.0400 7.6e-03 0.030 0.017 0.019 NA -0.002 1.3e-03 1.3e-02 9.1e-03 NA 6.0e-01
8 TCGA Breast Invasive Carcinoma 0.0354 0.0169 4.3e-05 0.015 0.024 0.017 NA 0.017 4.2e-04 1.0e-05 1.7e-04 NA 1.8e-04
9 TCGA Head and Neck Squamous Cell Carcinoma 0.0698 0.0375 2.1e-03 0.015 0.020 0.017 NA 0.021 6.9e-03 2.4e-03 4.5e-03 NA 1.9e-03
10 TCGA Kidney Renal Papillary Cell Carcinoma 0.1510 0.0730 1.1e-03 0.045 0.073 0.056 NA 0.053 1.3e-03 5.6e-05 4.0e-04 NA 5.5e-04
11 TCGA Lung Adenocarcinoma 0.0481 0.0276 6.7e-03 0.000 0.000 -0.001 NA -0.001 3.7e-01 2.9e-01 5.5e-01 NA 4.7e-01
12 TCGA Lung Squamous Cell Carcinoma 0.1170 0.0463 6.2e-07 0.077 0.075 0.071 NA 0.074 4.6e-09 6.4e-09 1.7e-08 NA 8.2e-09
13 TCGA Prostate Adenocarcinoma 0.1224 0.0682 7.5e-04 0.021 0.017 0.057 NA 0.022 2.4e-03 6.1e-03 1.3e-06 NA 2.2e-03
14 TCGA Thyroid Carcinoma 0.0940 0.0390 2.6e-04 0.049 0.041 0.036 NA 0.041 1.4e-05 6.6e-05 1.8e-04 NA 7.4e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.5 0.7 1.5 1.1 -1.1 -1.0 -1.1 -1.2 -0.7 0.0 -0.6 -0.5 0.4 -0.6 -0.3 1.1 -1.2
Bipolar Disorder or Schizophrenia 0.6 1.4 8.5 2.9 -1.0 -0.8 -1.1 -1.4 -0.7 0.0 -0.7 0.6 0.9 -0.5 0.4 1.0 -1.8
Depressed Affect (Nagel 2018) 0.6 1.3 7.9 2.8 0.7 0.6 0.8 0.1 1.1 1.4 0.2 0.9 -1.5 1.1 1.5 -0.2 -0.1
Depression (Nagel 2018) 1.0 1.5 4.8 2.2 1.2 1.0 1.2 1.0 1.7 1.2 0.5 0.6 -1.0 1.6 1.6 -0.8 0.2
Intelligence (Savage-Jansen 2018) 0.3 0.8 2.7 -1.2 -0.5 -0.7 -0.5 -0.2 -0.5 -0.9 0.1 -1.6 0.0 -1.3 -1.2 1.0 -1.2
Neuroticism (Nagel 2018) 1.4 3.3 6.2 2.0 1.7 1.8 1.8 1.2 2.5 2.3 1.6 1.1 -2.4 2.1 2.2 -0.9 0.5
Schizophrenia (2018) 0.6 1.3 8.4 2.9 -1.1 -0.8 -1.1 -1.3 -0.8 0.0 -0.5 1.2 1.0 -0.2 0.7 0.0 -1.3
Schizophrenia vs Biploar Disorder 1.4 1.9 2.9 0.7 1.4 1.6 1.6 1.5 1.5 0.0 1.6 1.7 -0.6 1.5 1.3 -1.6 1.4
Worry (Nagel 2018) 0.7 1.4 3.4 1.6 0.8 1.0 0.9 0.3 1.6 1.4 1.1 0.4 -1.4 1.9 1.5 -0.5 -0.6
Alzheimer’s Disease (in mother) 0.2 0.3 0.9 -1.0 0.3 0.8 0.3 0.2 0.4 0.6 0.8 -0.1 -0.2 0.2 0.4 -0.4 0.7
Alzheimer’s Disease (in father) 1.2 1.3 6.8 -2.6 -0.6 -0.8 -0.6 -0.3 -0.5 -1.4 0.8 -0.5 2.1 -0.5 -1.5 -0.5 -0.4
Alzheimer’s Disease (including proxy) 0.7 0.9 7.7 -2.8 -0.2 0.2 -0.2 0.0 0.1 -0.2 1.8 0.1 1.3 0.1 -0.3 -0.6 0.2
Crohns Disease (2017) 2.5 5.5 10.2 -2.4 -3.2 -3.1 -3.1 -2.5 -2.5 -1.9 -1.6 -2.3 1.4 -2.2 -2.1 2.2 -1.1
Irritable Bowel Disease (IBD) 3.0 7.1 10.7 -0.7 -3.1 -3.3 -3.1 -3.0 -3.0 -2.5 -2.7 -2.1 2.3 -3.1 -2.7 2.6 -2.0
Ulcerative Colitis (UC) 2.0 3.7 6.7 1.2 -1.7 -2.0 -1.8 -2.2 -2.1 -1.7 -2.5 -0.5 2.0 -2.6 -1.9 2.2 -1.8
Major Depression (MDD) 0.9 1.0 3.2 0.9 -1.4 -1.4 -1.3 -1.2 -1.1 0.0 -0.3 -1.8 -0.4 -0.4 -0.8 0.2 -1.1
Reaction Time 0.3 0.6 2.2 1.5 -0.2 -0.3 -0.4 -0.6 -0.3 -0.7 -0.0 -0.3 0.9 -0.5 -0.4 1.1 -1.4
Verbal and Numeric Reasoning (VNR) 0.4 1.0 4.9 0.0 -0.5 -0.6 -0.5 -0.2 -0.7 -1.1 -1.1 -2.2 0.1 -1.5 -1.4 0.4 -0.7
Breast Cancer 0.2 0.6 3.2 1.4 0.4 0.4 0.5 -0.3 0.0 0.8 -0.0 0.1 -0.6 0.7 1.8 -1.0 0.0
Ovarian Cancer 0.4 0.5 1.1 1.0 -0.7 -0.9 -0.7 -0.6 -0.8 -1.0 -0.5 -1.1 0.5 -0.0 -0.5 0.6 -0.7
Prostate Cancer 1.1 1.6 6.0 -0.7 1.2 1.3 1.3 0.4 -0.3 1.0 -1.2 -1.6 -2.4 -1.0 0.3 -1.7 1.4
Age at First Birth 0.6 0.8 6.2 2.5 0.0 0.2 0.1 -0.5 0.1 0.5 -0.2 0.9 -0.2 0.8 1.6 -0.3 -0.5
Bipolar Disorder (2011) 0.9 0.9 3.0 1.5 -1.6 0.0 -1.6 0.0 -1.7 0.0 -0.6 0.2 0.6 -0.4 -0.3 0.0 -1.1
Body Mass Index (BMI) (2010) 0.3 0.4 2.0 -0.8 0.7 0.4 0.5 0.7 -0.0 0.3 0.2 0.9 -0.0 0.5 0.2 -0.5 1.4
Coronary Artery Disease (CAD) 0.4 0.4 2.5 1.4 0.4 0.2 0.6 -0.1 0.7 0.0 -0.0 -0.4 -1.6 -0.0 0.3 0.0 -0.5
Crohns Disease (2012) 1.9 3.1 5.9 -1.5 -2.4 -2.2 -2.3 -2.2 -2.1 -1.2 -1.1 -2.0 0.8 -1.9 -1.5 1.1 -1.2
Mean Putamen Volume 1.5 1.7 3.2 0.0 -1.8 -1.6 -1.6 -1.5 -1.3 -1.1 -0.3 -1.3 -0.1 -1.2 -1.6 1.8 -1.2
Fasting Glucose 0.4 0.5 2.2 -1.2 0.3 0.6 0.4 1.0 0.8 0.9 1.5 0.3 -0.3 0.2 0.5 -0.1 0.6
HbA1C 1.3 1.5 2.7 -0.6 1.4 1.1 1.4 1.3 1.1 1.6 -0.6 0.4 -1.6 0.4 1.3 -1.6 1.4
HDL Cholesterol 1.1 1.9 7.4 0.2 -1.1 -1.5 -1.2 -1.6 -0.9 -1.4 -1.6 -1.1 1.3 -1.3 -0.6 1.0 -2.7
LDL Cholesterol 0.1 0.2 1.2 0.0 0.0 0.3 0.1 0.2 0.5 0.6 1.1 0.3 -0.4 0.6 0.3 -0.1 0.2
Lupus 0.6 0.9 2.1 -1.3 1.1 1.3 1.1 1.4 0.2 0.9 -0.1 0.2 -1.5 0.3 -0.3 -0.3 1.5
Neuroticism (2016) 0.5 0.7 3.3 1.7 -0.2 0.2 -0.1 0.0 0.6 1.1 0.5 -0.3 -1.8 0.8 0.5 0.1 -0.6
Primary Biliary Cirrhosis 0.9 1.3 6.4 2.5 -1.3 -1.2 -1.3 -1.8 -0.8 0.2 -0.5 0.6 -0.1 0.2 -0.1 0.5 -1.5
Rheumatoid Arthritis 1.5 2.1 6.2 -2.1 -1.1 -1.2 -1.4 -0.9 -1.3 0.0 -1.2 -1.7 0.5 -1.8 -2.5 1.7 -0.8
Schizophrenia (2014) 0.5 1.1 8.3 2.9 -0.7 -0.2 -0.7 -1.0 -0.6 0.0 0.1 1.6 0.4 0.4 1.2 0.0 -0.4
Triglycerides 0.2 0.4 2.6 -1.6 -0.2 0.1 -0.1 0.3 -0.4 0.2 0.2 0.2 -0.3 0.2 -0.4 -0.3 1.5
Type 2 Diabetes (T2D) (2012) 0.3 0.4 2.0 -0.9 0.2 0.5 0.2 0.3 -0.2 0.0 -0.3 -1.4 -1.2 -0.4 -0.1 0.3 -0.2
Ulcerative Colitis 2.8 4.1 6.9 1.1 -2.3 -2.4 -2.4 -2.6 -2.5 0.0 -2.3 -1.7 1.7 -1.9 -2.0 1.0 -2.4
Blood Eosinophil Count 0.4 3.1 8.0 -2.1 1.6 1.0 1.5 2.3 2.2 1.8 2.8 0.5 -1.6 1.8 1.3 -1.1 1.6
Blood Platelet Count 0.3 3.7 19.3 -1.8 -0.9 -0.7 -0.9 -0.1 -0.6 -2.5 1.8 0.5 4.4 -0.3 -2.9 -3.0 0.0
Blood Red Count 0.4 3.6 6.4 1.0 1.9 2.1 2.1 1.5 2.5 2.3 2.5 2.4 -1.9 2.1 2.0 -0.4 -0.0
Blood White Count 0.0 0.3 0.9 0.8 -0.5 -0.3 -0.3 0.1 0.3 -0.4 0.5 -0.5 0.7 0.0 -0.4 -0.3 -1.0
Heel T-Score 0.2 1.8 6.6 -2.6 1.0 1.3 1.4 1.9 1.2 0.8 1.8 -1.1 -1.0 0.4 0.2 -0.7 1.4
BMI 0.1 0.8 2.8 1.0 0.3 -0.5 0.0 -0.5 -0.5 -1.3 -1.0 1.4 1.7 0.0 0.6 0.2 -1.4
Height 0.4 8.2 28.1 -5.3 -1.6 -2.4 -1.8 -1.0 -3.5 -3.8 -2.0 -1.2 3.2 -3.6 -4.2 0.8 -0.1
Waist Hip Ratio (WHR) 0.6 2.6 9.9 0.3 1.2 1.6 1.4 0.8 0.9 2.4 2.0 0.7 -3.1 1.6 1.6 -1.3 1.3
Systolic Blood Pressure 0.1 0.3 0.9 -0.9 -0.7 0.1 -0.3 -0.0 -0.6 0.5 0.9 -0.6 -0.9 -0.1 0.1 0.1 0.6
Smoking Status 0.2 0.4 1.6 -0.1 0.4 0.4 0.4 0.5 0.2 0.8 0.9 0.5 -0.3 0.9 0.7 -0.8 1.3
Allergy or Eczema 0.9 2.4 3.4 -1.2 1.7 1.6 1.7 1.7 1.7 1.8 1.6 1.2 -1.9 1.7 1.4 -1.1 1.2
Cardiovascular Disease 0.2 0.5 1.9 -0.9 0.8 0.9 0.9 0.7 0.5 0.6 0.5 0.3 -1.4 -0.2 0.9 0.6 0.0
Hypothyroidism (self reported) 0.8 1.9 3.3 -0.3 -1.8 -1.8 -1.8 -1.7 -1.8 -1.4 -1.3 -1.2 1.1 -1.2 -1.2 1.2 -0.1
Respiratory disease 0.3 0.7 3.7 0.9 -0.4 -0.8 -0.4 -0.8 -1.1 -0.6 -1.9 0.7 1.2 -0.3 -0.1 -0.1 0.1
Type 2 Diabetes (T2D) (2018) 6.9 12.9 30.6 -0.7 3.8 3.9 4.0 3.6 4.0 4.7 2.8 1.0 -5.5 3.3 4.4 -1.7 3.1
Lung FEV1/FVC ratio 0.1 0.7 2.3 0.4 0.5 0.6 0.7 1.1 1.5 0.8 0.3 -0.6 -0.5 1.0 1.5 -0.5 1.0
Lung FVC 0.2 1.2 3.1 -1.0 -1.1 -0.9 -1.0 -0.6 -0.0 -1.4 0.8 -1.1 1.8 -0.7 -1.7 0.8 -1.2
Neuroticism 0.4 1.0 3.7 1.9 0.5 0.4 0.6 0.3 1.7 1.0 1.0 0.3 -1.0 1.1 1.1 0.5 -1.1
Chronotype (morning person) 0.4 1.0 2.6 1.6 -0.7 -0.7 -0.7 -0.9 -0.2 -1.1 -1.3 0.1 1.5 -0.9 -0.5 1.1 -1.5
Hair Pigment 0.0 0.6 4.3 0.7 0.2 0.5 0.1 0.0 0.2 1.0 -0.1 -0.5 -2.1 0.6 0.8 -0.9 0.2
Tanning 0.4 4.9 11.1 -0.4 -2.5 -2.1 -2.5 -1.9 -2.2 -2.1 -0.5 -3.0 1.9 -2.4 -3.3 1.9 -2.1
Hand grip strength (left) 1.8 4.8 9.1 -1.6 -3.0 -3.0 -2.9 -2.1 -2.2 -2.0 -0.8 -2.0 1.6 -1.6 -3.0 2.2 -1.3
Number of treatments/medications taken 1.9 3.5 5.6 -0.4 2.4 2.2 2.4 2.0 1.9 1.8 1.9 2.3 -1.8 1.4 2.1 -1.4 0.9
Average weekly spirits intake 0.7 0.8 2.2 0.4 -0.6 -0.6 -0.6 -0.8 -0.8 -1.5 -1.0 0.2 1.3 -1.1 -0.9 0.7 -1.3
Sensitivity / hurt feelings 0.5 0.8 2.4 -0.1 1.3 1.3 1.2 1.2 1.6 -0.5 0.6 -0.1 0.9 0.2 0.4 -0.6 -0.5
Frequency of depressed mood in last 2 weeks 0.5 0.7 6.0 2.5 0.1 -0.1 0.1 -0.1 0.6 0.5 -0.3 -0.5 -0.6 0.5 1.1 0.4 -0.8
Hearing difficulty/problems: Yes 0.3 0.5 2.5 1.6 -0.3 0.1 -0.2 -0.5 -0.1 0.2 1.1 0.5 0.1 0.9 1.0 -1.1 -0.2
Relative age of first facial hair 0.4 0.8 3.6 1.9 0.4 0.6 0.5 0.5 0.8 0.7 0.6 1.4 -0.2 0.9 1.1 0.0 -1.1
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 4.4 -0.0 0.8 0.5 0.8 0.8 0.5 -0.0 0.4 0.8 0.6 0.8 0.9 -2.1 0.4
Ever used hormone-replacement therapy (HRT) 2.6 3.4 5.0 -1.7 2.2 1.9 2.1 1.9 2.1 1.6 1.6 1.8 -1.8 1.5 1.1 -2.0 2.2
Ever had hysterectomy (womb removed) 0.5 0.5 3.4 -1.8 -0.1 -0.1 0.0 0.1 0.4 0.2 0.6 0.9 -0.1 1.0 -0.3 -1.1 0.4
Systolic blood pressure, automated reading 0.2 0.6 1.2 -1.0 0.6 1.0 0.7 0.9 0.4 0.6 1.0 0.3 -1.1 0.5 0.5 -0.1 0.9
Eye problems/disorders: Diabetes related eye disease 6.3 7.0 11.4 0.3 3.0 3.2 3.1 2.8 3.3 3.1 2.3 2.3 -1.8 2.2 3.4 -1.9 2.5
Angina 0.1 0.2 1.1 -1.1 0.1 0.2 0.2 0.3 0.0 -0.1 0.3 0.6 0.1 -0.4 0.0 0.4 0.3
Medication for hormone replacement therapy 1.5 1.6 7.1 -2.7 1.0 0.9 1.1 1.2 0.9 1.2 0.5 0.5 -1.7 0.7 0.4 -0.8 2.1
Vitamin and mineral supplements 0.8 1.1 3.3 -0.0 1.2 1.1 1.2 0.9 1.4 0.9 0.5 1.8 -0.6 1.0 1.6 0.5 0.6
Supplements: Zinc 1.0 1.1 3.8 -1.3 0.6 0.8 0.6 1.0 0.5 0.6 2.0 1.3 -0.4 1.1 -0.1 -1.4 1.4
Medication: Co-codamol 1.8 2.1 7.4 0.4 1.2 1.2 1.3 0.8 1.6 1.4 2.7 1.2 -0.5 2.0 1.0 -2.0 1.0
Medication: Metformin 6.6 9.3 19.4 0.4 3.2 3.2 3.3 3.3 3.9 4.0 2.7 0.9 -4.4 3.2 3.5 -1.5 2.1
Diabetes (father) 1.1 1.4 10.7 0.5 0.0 0.2 0.1 0.0 0.3 1.1 -0.7 -2.1 -3.3 -0.3 0.5 1.6 -0.1
Diabetes (mother) 2.0 2.5 5.4 0.4 2.2 2.1 2.1 1.4 1.4 1.8 0.2 0.2 -2.3 1.0 2.1 -1.6 1.0
Severe depression (siblings) 0.2 0.3 1.3 -0.2 -0.6 -0.4 -0.5 -0.5 -0.1 0.5 0.0 -0.1 -0.3 1.0 1.1 -0.0 -0.4
Pack years adult smoking proportion 0.7 1.0 6.3 -2.5 -0.2 -0.5 -0.3 0.0 -0.1 -0.8 0.3 1.1 2.0 -0.3 -1.1 -0.2 0.0
Impedance of leg (right) 0.1 0.7 2.2 -0.7 -1.5 -0.6 -1.2 -0.9 -0.7 0.1 0.2 -0.7 -0.4 -0.2 -1.5 0.2 0.5
Leg fat-free mass (left) 0.1 0.6 3.1 -0.9 0.6 -0.5 0.3 0.2 -0.5 -1.3 -0.7 0.8 1.8 -1.0 -0.1 0.2 -0.1
Trunk fat percentage 0.8 3.3 9.4 -0.4 2.8 2.3 2.6 2.1 1.7 0.6 1.1 3.1 0.1 1.3 1.8 -1.6 1.0
Hand grip strength (right) 2.5 6.7 11.9 -1.4 -3.3 -3.5 -3.2 -2.3 -2.4 -2.9 -1.8 -1.9 2.6 -2.1 -2.9 3.0 -2.1
Townsend deprivation index at recruitment 0.9 1.3 2.5 -0.1 -0.9 -1.4 -1.0 -1.4 -1.2 -1.2 -1.2 -0.4 1.4 -1.3 -0.2 1.6 -1.4
Current tobacco smoking 0.4 0.6 3.4 -1.8 0.1 -0.1 0.1 0.7 -0.1 0.7 0.3 0.2 -1.1 0.8 -0.1 -0.5 1.4
Average weekly fortified wine intake 0.9 1.1 7.1 2.7 0.8 1.1 0.8 0.3 0.5 0.7 -0.1 1.2 0.3 0.8 1.1 -1.3 -0.3
Maternal smoking around birth 0.5 0.7 2.0 -0.1 0.8 0.7 0.8 0.8 1.3 0.9 0.8 0.6 -1.4 0.8 1.1 -0.3 0.3
Fed-up feelings 0.7 1.4 4.4 1.2 0.7 1.0 0.8 0.4 1.1 1.6 1.1 1.3 -2.1 1.3 1.5 0.5 0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.5 4.5 2.1 -0.1 -0.3 -0.2 -0.2 0.5 -0.3 0.1 -0.2 0.6 0.4 0.1 0.3 -0.8
Relative age voice broke 0.2 0.4 0.8 0.6 0.8 0.5 0.9 0.7 0.8 0.7 0.4 0.5 -0.6 0.6 0.7 -0.2 0.1
Taking other prescription medications 0.3 0.4 1.4 1.1 -0.2 -0.6 -0.2 -0.2 0.4 -0.0 0.8 0.9 0.5 0.7 0.4 -0.6 -1.2
Age when periods started (menarche) 0.4 0.9 1.6 -1.1 0.9 0.8 1.0 1.3 1.2 0.7 1.0 0.6 -0.3 0.7 0.8 -0.9 1.3
Bilateral oophorectomy (both ovaries removed) 2.8 3.2 6.6 -0.6 1.0 1.3 1.2 1.5 2.1 2.6 2.3 1.6 -1.4 2.2 2.1 -1.3 2.6
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.8 4.3 -2.1 0.3 -0.2 0.3 0.9 -0.4 -1.2 -0.2 -0.9 0.8 -0.7 -1.5 -0.2 0.1
Tinnitus: Yes, but not now, but have in the past 2.6 2.8 4.2 -0.2 2.0 1.8 1.8 1.7 1.4 1.5 1.0 2.0 -1.6 2.1 2.0 -1.6 1.4
Qualifications: CSEs or equivalent 0.2 0.2 1.3 0.4 -0.1 -0.2 -0.2 -0.4 -0.6 -0.1 -1.1 -0.2 -0.7 0.2 -0.3 -0.1 -0.5
Serious illness, injury or assault to yourself 0.6 0.7 4.7 -0.5 0.2 0.4 0.3 0.2 -0.6 0.1 0.2 1.3 0.4 0.8 0.7 -2.2 1.3
High blood pressure 0.7 2.0 3.8 -1.1 1.7 1.9 1.9 1.5 1.0 1.1 1.6 0.9 -1.5 0.7 1.0 -1.8 1.3
Hayfever, allergic rhinitis or eczema 0.9 1.9 3.8 -0.7 1.2 1.2 1.2 1.3 1.4 1.5 1.9 0.8 -1.3 1.9 1.3 -1.8 0.7
Multivitamins +/- minerals 3.1 4.0 7.7 -0.1 -2.4 -2.5 -2.5 -1.9 -2.2 -2.3 -0.8 -2.4 1.9 -1.8 -2.8 0.1 -1.7
Stomach or abdominal pain in last month 0.2 0.3 1.1 0.5 0.2 0.1 0.1 0.2 0.1 0.3 1.0 1.0 0.1 0.8 -0.0 -0.8 0.5
Supplements: Glucosamine 1.9 2.4 4.2 0.7 -1.5 -1.6 -1.6 -1.5 -1.6 -1.5 -1.6 -0.8 0.9 -2.0 -1.7 2.0 -1.9
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 2.2 0.7 -0.9 -0.7 -0.7 -1.5 -1.2 -0.3 -0.4 -0.3 -0.0 -0.0 0.1 -0.5 -0.7
Medication: Atenolol 0.3 0.4 1.1 0.1 0.9 0.9 0.7 0.4 0.1 -0.6 -0.4 -0.1 -0.4 -1.0 -1.0 0.1 -1.0
Medication: Levothyroxine sodium 0.2 0.3 1.1 -0.1 -0.3 -0.4 -0.4 -0.4 -1.1 -0.5 -1.0 0.1 0.7 -0.3 -0.3 -0.6 0.7
Sitting height 0.1 1.0 6.3 -2.5 0.7 0.0 0.5 0.6 -0.5 -0.8 -0.9 -0.6 0.4 -1.4 -0.9 0.2 1.1
Chronic bronchitis/emphysema (father) 0.8 0.9 2.2 -0.9 0.7 1.0 0.8 0.4 0.7 1.5 1.1 1.3 -0.9 0.8 1.3 0.1 0.8
High blood pressure (mother) 0.7 1.0 4.9 2.2 -1.2 -0.5 -1.1 -1.0 -0.5 -0.5 -0.3 -0.2 0.9 -0.4 -0.2 1.8 -0.9
Body mass index (BMI) 0.4 1.7 5.8 0.6 2.2 1.3 1.9 1.2 0.8 -0.0 -0.1 2.4 0.6 0.7 1.6 -1.3 0.3
Impedance of leg (left) 0.1 0.6 2.1 -1.2 -1.4 -0.6 -1.1 -0.8 -0.6 -0.0 0.3 -0.6 -0.2 -0.2 -1.4 0.3 0.3
Leg predicted mass (left) 0.1 0.7 3.4 -0.8 0.6 -0.6 0.3 0.1 -0.6 -1.4 -0.8 0.8 1.8 -1.0 -0.1 0.2 -0.1
Trunk fat mass 0.4 1.8 6.7 -0.7 2.2 1.5 1.9 1.5 0.8 -0.2 0.3 2.6 0.9 0.5 1.2 -1.4 0.8
Waist circumference 0.4 1.5 4.8 -0.0 2.2 1.4 1.9 1.0 0.5 -0.1 -0.2 2.2 0.4 0.3 1.4 -1.5 0.5
Number of incorrect matches in round 0.3 0.6 3.5 0.2 0.1 0.3 0.0 0.4 1.0 0.2 1.9 0.1 0.4 1.4 0.4 -0.8 -0.1
Past tobacco smoking 0.1 0.1 0.3 -0.4 -0.4 0.1 -0.4 -0.2 -0.4 0.1 -0.3 0.4 -0.6 0.2 -0.5 -0.5 -0.5
Alcohol usually taken with meals 0.5 0.7 2.9 -1.7 0.0 0.1 0.2 0.8 0.8 1.1 1.3 0.3 -0.4 0.8 0.4 -1.1 0.9
Nervous feelings 1.4 2.5 5.4 2.1 1.0 1.7 1.2 0.8 2.0 2.2 1.5 0.7 -2.3 1.9 2.1 -0.2 -0.3
Frequency of tenseness / restlessness in last 2 weeks 3.6 5.6 10.0 1.9 2.2 2.2 2.2 2.1 3.2 3.0 2.1 1.4 -3.1 2.9 2.9 -1.5 1.4
Hearing difficulty/problems with background noise 0.4 0.6 2.1 1.5 0.1 0.1 0.2 -0.0 0.0 0.6 1.4 0.9 -0.3 1.0 0.8 -1.2 0.3
Hair/balding pattern: Pattern 2 1.2 1.5 4.5 2.1 -1.1 -1.2 -1.1 -1.7 -1.1 -0.7 -1.0 -0.8 0.4 -0.9 -1.1 0.8 -1.9
Had menopause 2.4 3.0 5.6 -1.8 2.3 2.4 2.2 2.1 1.6 1.3 1.7 0.9 -1.8 1.0 0.8 -1.9 1.5
Had other major operations 0.4 0.5 2.9 -0.8 0.0 0.0 0.1 0.3 0.3 0.5 1.6 -0.3 -1.7 0.4 -0.5 -0.2 -0.6
Forced vital capacity (FVC) 1.0 3.8 6.4 -1.3 -2.1 -2.2 -2.2 -1.9 -1.7 -2.5 -0.9 -1.9 2.0 -2.0 -2.5 1.4 -1.9
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 3.8 -1.6 1.5 1.1 1.6 2.0 0.7 -0.1 0.4 -0.2 -0.2 0.3 -0.3 -0.6 0.7
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 1.5 0.1 -0.7 -0.5 -0.6 -0.3 0.2 0.1 0.4 0.0 -0.6 0.3 0.3 0.8 -1.2
Qualifications: None of the above 0.2 0.5 3.5 1.9 0.6 0.2 0.5 -0.3 0.3 0.5 0.4 0.5 0.2 0.2 1.3 -0.0 -0.4
Financial difficulties in last 2 years 0.6 0.8 2.5 -0.4 1.4 0.8 1.3 1.5 1.6 0.4 0.6 0.3 -0.1 0.3 0.8 -0.4 0.4
Mouth/teeth dental problems 0.2 0.3 1.2 -1.1 0.1 0.2 0.1 0.6 -0.1 0.3 -0.4 0.3 -0.8 0.7 0.2 -0.0 0.9
Heart attack 1.3 1.6 2.9 -1.7 1.6 1.4 1.5 1.7 1.4 0.8 1.4 1.1 -1.0 0.8 1.1 -1.0 0.9
Allergy 0.9 2.1 6.1 -0.5 -1.6 -1.2 -1.6 -1.2 -1.3 -1.3 -0.9 -1.9 0.3 -1.9 -1.5 2.5 -1.0
Pain all over the body in last month 1.3 1.4 8.6 2.9 -0.3 -0.5 -0.4 -1.0 -1.0 -0.9 -1.0 1.1 1.5 -0.3 -0.3 -0.3 -1.5
Diabetes (self-reported) 7.2 11.1 16.3 -0.8 3.6 3.8 3.7 3.5 3.8 4.0 3.0 1.8 -4.0 3.5 3.9 -2.5 2.8
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 1.2 -1.0 0.5 0.5 0.4 0.4 0.6 0.3 1.1 0.4 0.2 0.7 0.3 -1.1 0.8
Medication: Ramipril 1.6 2.1 3.9 -1.9 1.8 2.0 1.8 1.6 1.5 0.9 1.3 0.9 -1.4 1.0 1.4 -1.5 0.3
Medication: Simvastatin 2.1 3.1 5.4 0.2 2.2 2.3 2.2 1.8 2.3 1.9 2.2 1.6 -1.5 1.3 1.8 -1.3 0.1
Fluid intelligence score 0.2 0.4 2.9 0.1 -0.3 -0.4 -0.2 0.3 0.2 -0.7 -0.4 -1.7 0.2 -0.6 -1.0 0.1 -0.2
Illnesses of siblings 0.3 0.5 2.2 0.2 -0.4 -0.5 -0.6 -0.3 -0.6 -1.0 -0.5 -0.6 0.6 -0.6 -1.5 0.1 -0.8
Neuroticism score 0.6 1.2 3.5 1.6 0.5 0.7 0.6 0.5 1.9 1.2 1.8 0.4 -0.9 1.5 1.3 0.0 -0.5
Weight 0.2 0.9 2.4 -1.1 1.4 0.3 1.0 0.6 -0.4 -1.2 -0.9 1.5 1.6 -0.7 0.2 -0.8 0.2
Impedance of arm (right) 0.1 0.5 1.6 -0.5 0.4 1.1 0.4 0.7 0.8 0.4 1.2 -0.7 -1.2 -0.0 -0.7 0.3 -0.1
Arm fat percentage (right) 0.5 2.0 6.1 0.6 2.5 1.9 2.2 1.5 1.1 0.1 0.2 2.2 0.4 0.6 1.6 -1.4 0.3
Trunk fat-free mass 0.3 1.9 8.1 -1.4 -0.5 -1.4 -0.8 -0.7 -1.7 -2.1 -1.5 -0.0 2.9 -1.7 -1.1 0.1 -0.1
Hip circumference 0.3 1.3 3.2 -0.6 1.8 0.9 1.4 0.8 -0.1 -1.3 -1.4 1.7 1.6 -0.5 0.6 -0.9 0.3
Time employed in main current job 0.9 1.1 2.3 0.4 -1.2 -1.4 -1.1 -1.1 -0.8 -0.5 -1.2 -1.5 -0.2 -1.0 -0.7 1.3 -1.3
Alcohol intake versus 10 years previously 0.4 0.6 2.0 0.8 -0.5 -0.4 -0.6 -0.8 -0.5 -0.7 0.1 -1.0 1.4 -0.1 -0.2 -1.0 -1.4
Father’s age at death 4.7 6.3 9.9 1.9 -3.0 -2.9 -3.1 -3.1 -3.1 -1.9 -2.6 -2.5 1.4 -2.7 -2.1 2.2 -1.7
Worrier / anxious feelings 0.8 1.5 4.0 1.2 0.8 1.0 0.9 0.8 1.9 1.2 1.9 1.4 -0.7 2.0 1.2 -0.4 -0.2
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.1 5.2 0.4 1.6 1.0 1.5 1.3 1.6 1.4 1.9 0.7 -1.1 1.7 1.8 -2.3 0.9
Falls in the last year 0.7 0.9 6.5 0.4 -0.0 -0.0 0.1 0.2 0.7 0.2 1.7 0.2 0.6 1.4 0.7 -2.5 -0.0
Hair/balding pattern: Pattern 3 0.7 1.0 2.1 0.9 0.9 1.4 1.0 0.8 0.9 1.2 0.5 1.3 -0.8 1.1 1.4 -0.7 0.9
Number of live births 0.6 0.8 2.3 -0.8 1.5 1.5 1.4 1.0 0.6 0.5 0.2 0.8 -0.5 -0.3 0.3 0.3 1.1
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 3.1 -0.9 -1.2 -1.3 -1.2 -0.8 -0.5 -1.8 -0.2 -1.4 1.4 -1.1 -1.6 0.7 -1.2
Pulse rate 0.9 1.5 8.2 -2.9 0.1 0.3 0.0 0.4 0.1 0.4 1.3 2.0 0.6 0.9 0.5 -0.5 2.3
Happiness 0.5 0.6 2.2 1.5 -0.8 -0.0 -0.6 -0.6 0.2 1.0 0.4 -0.3 -1.3 0.8 1.0 -0.3 -0.2
Noisy workplace 0.4 0.6 2.4 0.2 -0.4 -0.6 -0.4 -0.7 -0.6 -0.8 0.2 1.3 1.6 0.4 -0.3 -0.8 -0.7
Qualifications: A levels/AS levels or equivalent 0.1 0.1 0.4 -0.1 0.2 0.3 0.2 0.6 0.7 -0.1 0.6 -0.0 0.5 0.3 0.3 -0.2 0.3
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 3.5 -1.4 -0.6 -0.5 -0.7 -0.5 -1.0 -1.4 -0.3 -0.2 1.9 -0.8 -1.0 -0.3 0.0
Mouth/teeth dental problems: Dentures 0.2 0.3 1.4 0.8 0.2 0.5 0.1 -0.4 -0.2 -0.2 -0.1 0.7 1.2 -0.8 0.2 -0.6 -0.4
Asthma 0.4 0.7 2.8 1.0 0.8 0.3 0.7 0.3 0.1 0.5 -0.8 1.7 0.5 0.6 0.9 -1.4 0.9
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 1.2 -0.7 -0.1 -0.4 -0.1 0.1 -0.1 -0.3 0.7 1.1 0.3 0.3 -0.1 0.1 -0.1
Medication: Cholesterol lowering 1.9 3.0 6.4 -0.0 2.3 2.3 2.4 1.9 2.5 1.6 1.2 0.7 -2.5 0.8 2.2 -0.2 -0.2
Depression (self-reported) 0.9 1.1 3.7 1.3 -1.0 -0.5 -1.0 -1.3 -0.2 -1.1 -0.8 -0.8 0.7 -0.7 -0.4 1.7 -1.9
Medication: Lansoprazole 0.3 0.4 2.2 -1.5 -0.1 -0.3 -0.1 0.5 0.3 0.1 0.8 1.3 0.1 0.6 0.2 -0.0 0.3
Prospective memory result 0.1 0.1 0.1 -0.2 -0.3 -0.2 -0.4 -0.3 -0.3 -0.0 -0.0 -0.3 0.2 -0.3 -0.3 0.2 -0.3
Lung cancer (father) 0.2 0.2 0.8 0.6 -0.4 -0.9 -0.3 -0.4 -0.1 -0.0 -0.2 -0.2 0.4 0.2 0.4 0.7 -0.2
Illnesses of mother 0.5 0.6 1.8 -0.6 -0.5 -1.3 -0.6 -0.4 -0.1 -0.8 -0.5 -1.0 0.5 -0.9 -1.2 0.6 -1.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.1 5.9 -0.8 -1.9 -2.2 -2.0 -1.5 -1.1 -2.4 -0.8 -1.9 2.1 -1.5 -2.2 1.3 -2.0
Pulse wave Arterial Stiffness index 0.3 0.3 1.1 0.1 0.7 0.7 0.8 0.4 -0.1 0.4 -0.6 0.4 -1.0 0.5 0.7 -0.5 0.1
Impedance of arm (left) 0.4 2.0 4.5 -1.1 1.4 2.1 1.5 1.8 2.1 1.2 2.0 0.1 -1.9 0.9 0.2 -0.1 0.8
Arm fat mass (right) 0.3 1.3 4.3 -0.1 2.0 1.2 1.7 1.1 0.4 -0.6 -0.3 2.1 1.0 0.1 1.0 -1.0 0.1
Trunk predicted mass 0.3 1.9 7.9 -1.4 -0.5 -1.4 -0.7 -0.7 -1.6 -2.0 -1.6 -0.1 2.8 -1.8 -1.1 0.1 -0.0
Standing height 0.5 4.9 12.6 -3.5 -1.7 -2.1 -1.9 -1.3 -2.4 -2.6 -1.6 -1.8 2.1 -2.9 -3.0 1.3 -0.2
Length of working week for main job 0.7 0.7 2.7 0.1 0.4 0.1 0.3 0.3 0.9 -0.1 0.3 1.2 1.6 0.9 1.3 -1.4 0.6
Exposure to tobacco smoke at home 2.8 3.1 5.4 -0.5 2.3 2.3 2.3 2.0 2.1 1.8 1.3 2.2 -1.6 1.3 1.8 -0.2 1.6
Breastfed as a baby 0.3 0.4 1.5 0.2 -0.1 -0.6 -0.1 -0.6 -1.1 -0.4 -1.2 -0.7 0.3 -0.9 -0.4 0.4 0.5
Tense / ‘highly strung’ 0.3 0.6 2.3 0.2 -0.3 0.2 -0.2 -0.4 0.4 1.3 1.1 -0.4 -1.5 1.0 1.0 -0.2 -0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 2.7 1.3 -0.4 -0.2 -0.2 -0.3 0.4 1.0 0.1 0.3 -1.6 0.8 0.4 0.3 -0.6
Hair/balding pattern: Pattern 4 0.1 0.3 2.7 0.3 -0.0 -0.5 -0.1 -0.2 -0.1 -0.5 -0.3 -1.6 -0.5 -0.6 -0.2 0.3 -0.9
Birth weight of first child 0.4 0.7 2.1 -0.2 -0.6 -0.7 -0.6 -0.9 -1.0 -0.1 -1.0 -1.4 -1.1 -0.9 -0.8 -0.1 0.8
Peak expiratory flow (PEF) 0.1 0.2 0.7 -0.8 0.6 0.3 0.4 0.6 0.8 -0.5 0.7 -0.3 0.4 0.2 0.1 -0.2 0.1
Pulse wave reflection index 0.7 0.8 2.2 1.5 1.3 0.9 1.4 0.9 0.3 0.6 -0.5 0.3 -0.9 0.7 0.7 -0.9 0.7
Ever highly irritable/argumentative for 2 days 0.6 0.7 2.4 -1.6 0.4 0.8 0.5 0.7 0.9 0.6 1.4 0.3 -0.4 0.7 0.8 -0.1 1.1
Loud music exposure frequency 1.6 1.7 3.2 0.5 1.7 1.8 1.7 1.1 1.3 1.2 1.3 1.4 -0.8 1.3 1.7 -0.7 1.1
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 2.2 -1.3 1.1 1.1 1.1 1.3 1.1 0.7 0.5 0.4 -1.5 0.2 0.5 0.7 0.4
Mouth/teeth dental problems: Bleeding gums 0.9 1.2 3.0 1.3 -0.6 -1.0 -0.7 -1.1 -1.4 -1.3 -1.7 -0.5 1.0 -1.3 -0.6 0.6 -1.1
Blood clot in the leg (DVT) 1.3 1.7 4.5 1.5 2.1 1.5 1.9 1.1 1.3 0.4 -0.4 2.1 0.5 0.6 1.3 -1.2 0.0
Medication: Paracetamol 0.7 1.2 1.9 -0.5 1.0 1.0 1.0 0.9 1.1 1.2 1.2 0.9 -1.2 1.1 1.1 -1.3 1.4
Headache pain in last month 0.2 0.4 1.9 1.4 -0.5 -0.3 -0.6 -0.4 0.3 0.4 0.7 -0.1 -0.4 0.8 0.1 0.2 -0.9
Medication for cholesterol, blood pressure or diabetes 1.8 2.9 7.1 0.3 -2.7 -2.3 -2.6 -2.0 -1.9 -1.2 -0.8 -1.3 1.3 -0.8 -2.1 1.7 -0.8
Glaucoma (self-reported) 0.2 0.2 0.8 0.8 0.3 0.5 0.3 0.2 0.3 0.5 0.5 0.0 -0.9 0.4 0.5 -0.5 -0.3
Gout (self-reported) 0.1 0.1 0.7 -0.5 0.0 -0.1 0.1 -0.1 -0.3 -0.0 0.1 0.3 -0.3 0.5 0.2 -0.8 0.3
Hypothyroidism/myxoedema (self-reported) 0.4 0.8 1.6 -1.2 -1.0 -0.9 -1.1 -0.6 -1.3 -1.0 -0.7 -0.9 1.1 -0.5 -0.8 0.2 0.6
Medication: Amlodipine 0.2 0.2 2.4 0.1 0.3 0.3 0.5 0.4 -0.2 0.2 0.4 0.1 -0.1 0.3 0.3 -1.5 0.1
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.1 0.2 -0.1 -0.4 -0.1 -0.4 -1.1 -0.0 -1.1 0.5 0.6 -0.6 0.0 -0.7 1.1
Birth weight 0.2 0.4 1.3 -0.5 -0.2 -0.1 -0.1 -0.1 -0.2 -0.9 -0.5 -0.9 1.1 -0.4 -0.9 -0.8 -0.6
Chronic bronchitis/emphysema (mother) 0.4 0.5 1.6 -0.0 -1.2 -0.9 -1.1 -1.2 -1.2 -0.1 -0.4 -0.1 0.5 0.0 -0.3 -0.5 0.1
High blood pressure (siblings) 0.1 0.2 1.3 -0.1 -0.1 0.1 0.1 -0.1 0.2 0.5 0.1 0.3 -0.8 0.2 1.1 0.8 0.1
Forced vital capacity (FVC), Best measure 1.4 5.2 8.8 -1.2 -2.5 -2.8 -2.6 -2.2 -2.0 -2.8 -1.2 -2.1 2.4 -2.2 -3.0 1.8 -2.4
Body fat percentage 0.7 2.9 8.6 -0.2 2.6 2.0 2.4 1.8 1.5 0.4 0.8 2.9 0.4 1.2 1.8 -1.7 0.9
Leg fat percentage (right) 0.5 1.7 7.2 0.4 1.8 1.3 1.6 1.1 0.6 -0.0 -0.1 2.7 0.8 0.8 1.3 -1.8 0.7
Arm fat-free mass (right) 0.3 1.3 6.7 -1.4 -0.0 -1.1 -0.3 -0.4 -1.1 -1.8 -1.2 0.7 2.6 -1.2 -0.5 0.1 0.2
Exposure to tobacco smoke outside home 3.6 4.8 7.6 -0.8 2.5 2.3 2.5 2.0 2.5 2.4 1.9 2.4 -1.1 2.2 2.8 -1.5 2.7
Comparative body size at age 10 0.2 0.4 3.1 1.7 0.5 0.5 0.5 0.2 0.5 -0.1 -0.6 0.3 0.6 0.2 0.7 0.2 -0.7
Number of full brothers 0.4 0.5 3.2 -0.3 -0.1 -0.3 -0.1 0.2 -0.5 -1.0 0.1 -0.7 1.8 -0.3 -0.8 -0.8 0.5
Worry too long after embarrassment 0.2 0.3 0.8 0.1 0.5 0.7 0.5 0.3 0.9 0.4 0.8 -0.3 -0.6 0.2 0.6 0.1 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 2.6 0.9 -1.2 -0.9 -1.1 -1.2 -0.4 -0.5 -0.3 -0.1 0.4 -0.9 -0.7 1.6 -1.5
Wheeze or whistling in the chest in last year 0.3 0.5 1.6 0.7 -0.7 -1.2 -0.7 -0.5 -0.5 -0.5 0.4 0.9 1.2 -0.2 -0.5 0.2 -0.5
Number of children fathered 0.8 0.9 2.4 0.4 -1.2 -1.3 -1.1 -0.7 -0.3 -0.4 0.6 -0.9 0.6 -0.7 -1.2 1.5 -0.9
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.7 -1.2 0.8 0.7 0.7 0.9 0.9 0.6 0.9 1.3 0.0 1.0 0.3 -0.4 1.1
Age at first live birth 0.9 1.7 4.2 1.3 -1.6 -1.5 -1.6 -1.5 -0.7 -1.4 -0.3 -0.3 1.7 -0.4 -0.3 1.4 -2.1
Pulse wave peak to peak time 0.6 0.7 1.8 -0.4 -1.0 -1.0 -1.2 -0.6 -0.3 -0.7 0.4 -0.7 1.3 -0.9 -1.0 0.7 -0.4
Health satisfaction 1.5 1.9 3.9 0.6 1.5 1.6 1.5 1.3 1.4 1.1 1.4 1.2 -0.5 1.3 2.0 -1.8 1.5
Shortness of breath walking on level ground 1.1 1.3 2.7 0.3 1.6 1.4 1.4 1.1 1.2 0.6 1.1 1.6 0.1 0.8 1.2 -1.4 0.8
Qualifications: College or University degree 0.5 1.5 3.5 0.7 -1.5 -1.3 -1.5 -1.4 -1.0 -1.3 -1.2 -1.9 1.2 -1.3 -0.8 0.6 -0.9
Eye problems/disorders: None of the above 0.8 0.9 2.6 0.0 -1.3 -1.3 -1.3 -1.0 -1.3 -0.5 -0.4 -1.6 0.4 -0.8 -0.8 0.5 -0.2
Mouth/teeth dental problems: Loose teeth 2.2 2.6 4.6 0.2 1.6 1.7 1.8 1.8 2.0 2.1 1.4 1.6 -1.8 1.2 1.8 -0.7 2.0
Emphysema/chronic bronchitis 1.3 1.5 3.0 1.3 1.1 1.2 1.2 1.2 1.0 1.7 0.8 1.2 -1.1 1.4 1.1 -1.3 1.2
Medication for pain relief, constipation, heartburn 3.6 6.2 10.3 1.7 -2.3 -2.3 -2.4 -2.7 -2.7 -2.6 -3.2 -2.5 2.2 -2.9 -2.5 2.0 -2.4
Neck or shoulder pain in last month 1.9 2.7 6.2 -0.3 1.5 1.2 1.4 1.6 1.8 1.6 2.5 1.9 -1.1 2.3 1.3 -1.8 1.4
Medication: Blood pressure 0.2 0.4 1.1 -0.4 0.8 0.8 0.8 0.4 0.1 0.4 0.3 0.6 -0.5 0.2 0.8 -1.1 0.4
Angina (self-reported) 0.1 0.1 1.0 -1.0 -0.1 0.1 -0.0 0.0 -0.2 -0.1 0.3 0.8 0.2 -0.4 -0.1 0.2 0.3
Migraine (self-reported) 0.3 0.3 1.2 0.9 -0.5 -0.6 -0.5 -0.5 0.3 0.3 0.8 -0.6 0.3 0.2 0.1 -0.1 -1.1
Medication: Ibuprofen 0.2 0.2 1.0 -1.0 -0.1 -0.3 -0.1 0.2 -0.0 -0.2 0.8 1.0 0.3 0.2 -0.2 0.4 0.3
Medication: Allopurinol 0.1 0.1 0.8 -0.9 -0.1 -0.1 -0.1 -0.0 -0.3 0.2 0.1 -0.1 -0.8 0.2 0.1 0.3 0.0
Medication: Omeprazole 0.8 0.9 2.4 -0.0 1.2 0.9 1.1 0.9 1.5 0.8 1.1 0.5 -0.5 1.2 1.1 -1.2 -0.2
Medication: Seretide 50 evohaler 0.6 0.7 2.0 -0.3 0.4 0.6 0.5 0.3 0.8 1.2 1.4 1.2 -0.0 1.1 0.9 -0.9 0.7
Mean time to correctly identify matches 0.1 0.1 0.6 0.8 0.4 0.3 0.3 0.1 -0.1 -0.1 0.2 -0.2 0.1 -0.3 -0.2 -0.1 -0.7
Heart disease (mother) 0.4 0.5 2.1 -0.0 0.6 0.8 0.7 0.5 0.2 0.1 0.7 1.4 0.1 1.1 0.6 -1.0 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 0.9 0.9 0.9 0.5 0.9 0.4 0.5 0.8 -0.3 0.4 -0.9 0.1 0.6 -0.7 0.8
Whole body fat mass 0.4 1.7 6.1 -0.6 2.1 1.3 1.8 1.3 0.8 -0.3 0.2 2.5 1.1 0.5 1.2 -1.4 0.6
Leg fat mass (right) 0.3 1.1 5.1 -0.2 1.5 0.7 1.3 0.7 0.0 -0.7 -0.4 2.3 1.4 0.1 0.8 -1.3 0.5
Arm predicted mass (right) 0.2 1.1 5.3 -1.4 0.1 -1.0 -0.1 -0.3 -1.0 -1.6 -1.3 0.8 2.3 -1.2 -0.5 0.0 0.2
Pulse rate, automated reading 1.5 4.7 14.7 -3.8 1.7 1.5 1.7 2.1 1.3 1.7 2.5 2.6 -0.3 2.2 1.2 -2.2 3.2
Alcohol intake frequency. 0.1 0.1 0.3 0.2 0.4 0.5 0.3 0.3 0.3 0.4 -0.1 0.3 0.4 0.2 0.6 -0.3 0.3
Comparative height size at age 10 0.5 2.8 6.4 -2.5 -1.1 -1.4 -1.3 -1.0 -1.8 -2.5 -1.3 -1.5 2.1 -1.8 -2.1 0.6 -1.5
Number of full sisters 0.4 0.5 2.2 -0.0 0.6 0.5 0.6 0.4 0.2 0.7 1.0 0.3 -0.2 0.6 0.8 -1.5 1.3
Suffer from ‘nerves’ 1.5 2.4 9.3 3.0 1.3 1.6 1.4 0.5 1.9 1.7 0.6 0.1 -1.4 1.6 2.4 -0.5 -0.4
Overall health rating 1.4 3.0 7.0 -0.0 2.5 2.0 2.4 1.7 1.5 1.1 1.2 1.2 -1.3 1.6 2.0 -2.6 1.1
Chest pain or discomfort 1.8 2.6 4.1 0.7 1.7 1.8 1.8 1.6 1.8 1.8 1.4 1.7 -1.3 1.8 2.0 -1.2 1.4
Had major operations 0.4 0.5 3.4 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.6 -0.2 1.8 1.2 0.4 0.3 -0.6 0.3
Age at last live birth 1.4 2.1 5.1 1.1 -1.6 -1.7 -1.8 -1.8 -1.0 -1.2 -0.8 -0.7 1.7 -1.1 -0.8 2.3 -1.7
Family relationship satisfaction 0.3 0.3 2.0 1.4 -0.6 -0.0 -0.4 -0.5 0.2 0.8 0.2 -0.5 -0.6 0.1 0.4 0.4 0.5
Leg pain on walking 0.2 0.3 1.5 0.4 0.0 -0.1 -0.1 -0.0 -0.1 -0.8 0.0 0.9 1.2 0.2 0.2 -0.8 -0.3
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 1.4 0.1 1.0 0.6 0.9 1.0 1.2 0.5 0.6 0.8 0.0 1.1 0.8 -0.7 0.2
Commuting to job workplace: Car/motor vehicle 0.9 1.0 2.0 -0.1 1.4 1.1 1.3 1.4 1.3 0.9 0.1 1.0 -0.1 1.1 1.1 -0.6 0.7
Illness, injury, bereavement, stress in last 2 years 1.7 2.1 5.3 2.0 -1.1 -1.2 -1.2 -1.3 -0.5 -1.3 -1.3 -1.2 0.8 -1.3 -1.4 2.3 -2.2
Medication: Aspirin 3.3 4.4 8.1 -1.2 2.6 2.5 2.6 2.8 2.3 1.8 2.2 0.9 -2.0 1.6 1.9 -2.3 1.5
Supplements: Vitamin C 1.2 1.4 2.2 0.1 -1.3 -1.3 -1.3 -1.3 -1.4 -1.5 -1.4 -1.3 1.0 -1.2 -1.2 0.4 -1.2
Knee pain experienced in last month 1.1 1.6 4.0 -0.2 -1.9 -2.0 -1.9 -1.3 -1.0 -0.9 0.8 -0.9 1.6 -0.6 -1.4 0.9 -1.1
Hypertension (Self-reported) 0.8 2.3 4.2 -1.0 1.8 2.0 1.9 1.4 1.1 1.4 1.6 1.1 -1.9 0.7 1.1 -1.9 1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.8 -0.0 -0.4 -0.6 -0.5 0.0 0.6 0.2 1.3 1.3 0.5 1.2 0.4 -0.7 -0.0
Illnesses of father: Heart disease 2.4 3.3 4.9 -0.5 2.0 1.8 1.9 1.9 2.2 2.0 1.8 1.4 -1.9 1.8 2.2 -1.7 2.0
Illnesses of siblings: Diabetes 0.1 0.2 0.8 -0.3 0.3 0.2 0.2 -0.1 -0.1 0.1 -0.9 -0.8 -0.6 -0.3 0.4 0.2 0.2
Smoking status: Previous 0.1 0.2 0.5 0.4 0.7 0.4 0.7 0.5 0.5 0.1 0.6 -0.4 0.2 -0.0 0.5 -0.1 0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.7 2.9 -1.1 -1.0 -1.3 -1.1 -1.0 -1.6 -1.6 -1.6 -1.1 1.3 -1.7 -1.7 0.2 -0.7
Whole body fat-free mass 0.2 1.4 6.8 -1.1 -0.1 -1.2 -0.4 -0.5 -1.2 -1.9 -1.3 0.3 2.6 -1.4 -0.7 0.1 -0.1
Leg fat-free mass (right) 0.1 0.7 3.1 -1.0 0.8 -0.5 0.4 0.2 -0.4 -1.4 -0.7 0.8 1.8 -0.9 -0.0 0.2 -0.2
Arm fat percentage (left) 0.7 2.6 7.9 0.4 2.8 2.1 2.5 1.8 1.5 0.1 0.3 2.5 0.5 0.8 1.8 -1.4 0.4
Average weekly red wine intake 0.2 0.3 1.3 -1.1 0.2 0.5 0.3 0.4 0.3 0.4 -0.0 -0.9 -0.5 -0.4 0.0 -0.2 1.1
Handedness (chirality/laterality): Left-handed 0.3 0.4 2.7 1.6 0.1 0.1 -0.0 -0.6 -0.5 0.4 -0.6 -0.6 -0.9 -0.1 0.5 -0.0 -0.3
Mood swings 0.5 0.8 2.7 1.6 0.7 0.5 0.7 0.4 1.4 1.0 0.7 0.3 -1.2 1.0 1.3 -0.1 -0.4
Loneliness, isolation 0.2 0.3 2.1 1.4 0.4 0.5 0.4 -0.0 0.2 0.3 -0.5 -0.1 -0.3 -0.9 0.7 0.4 -0.1
Long-standing illness, disability or infirmity 0.2 0.3 0.9 1.0 0.6 0.0 0.6 0.1 0.6 0.7 0.4 0.5 -0.6 0.2 1.0 -0.7 -0.2
Ever had bowel cancer screening 0.3 0.3 1.7 0.4 0.4 0.5 0.5 0.2 0.6 0.7 0.6 -0.1 -1.3 -0.3 0.3 -0.6 -0.3
Diabetes diagnosed by doctor 9.9 16.3 30.2 0.1 4.2 4.5 4.3 4.0 4.5 5.2 3.2 2.1 -5.5 4.2 5.1 -2.6 3.5
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.5 2.8 0.4 0.5 0.6 0.4 0.1 0.1 0.4 -1.0 -0.4 -1.7 -0.4 0.2 1.0 0.3
Friendships satisfaction 0.5 0.6 3.1 1.0 -0.2 0.2 -0.0 -0.3 0.2 1.2 -0.1 -1.0 -1.8 -0.3 0.8 0.3 0.9
Qualifications: nursing, teaching 0.2 0.3 1.7 -1.3 0.1 0.6 0.1 0.7 0.3 0.3 0.3 -0.8 -1.0 0.4 -0.1 0.0 0.2
Commuting to job workplace: Walk 4.1 4.4 7.0 2.1 -2.1 -1.9 -2.2 -2.4 -2.1 -2.3 -2.2 -1.3 2.4 -2.6 -1.2 2.5 -1.8
Eye problems/disorders: Cataract 0.8 0.9 3.6 -0.4 0.8 1.0 0.8 0.8 0.9 0.8 0.6 1.9 -1.0 1.2 1.0 -0.6 0.7
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 2.2 0.8 -0.7 -0.8 -0.6 -0.5 0.4 -0.3 0.9 -1.5 0.2 -0.5 -1.1 0.5 -0.4
Medication for cholesterol 1.3 1.9 6.7 1.6 -1.2 -1.3 -1.3 -1.2 -0.7 -1.8 -1.7 -0.4 2.6 -1.0 -0.6 0.9 -1.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.3 2.8 -0.9 1.2 1.0 1.1 1.2 1.3 1.1 0.8 1.4 -0.3 1.1 1.1 -1.7 1.3
Back pain experienced in last month 1.7 2.5 4.5 -0.3 1.5 1.4 1.6 1.7 1.8 2.1 1.4 1.5 -2.1 1.8 1.9 -0.5 1.7
Mineral and other dietary supplements 1.1 1.5 2.9 -1.6 0.9 0.9 1.0 1.2 1.2 1.0 1.3 0.9 -0.5 1.7 1.5 -1.0 1.7
Breast cancer (self-reported) 3.0 3.6 5.9 1.1 -1.8 -2.1 -2.0 -2.0 -2.4 -1.8 -1.8 -1.3 1.2 -1.9 -2.2 2.1 -2.0
Asthma (self-reported) 0.4 0.7 2.7 1.1 0.8 0.3 0.7 0.3 0.1 0.8 -0.7 1.6 -0.0 0.7 0.9 -1.1 1.0
Osteoporosis (self-reported) 4.9 6.1 10.8 0.5 -3.3 -3.2 -3.3 -3.2 -3.1 -2.4 -2.4 -1.6 1.7 -1.7 -2.1 1.9 -2.4
Osteoarthritis (self-reported) 2.5 3.2 5.6 0.5 2.3 2.4 2.2 1.7 1.7 1.9 1.2 1.9 -2.2 1.6 1.9 -1.2 1.2
Medication: Aspirin 3.6 4.7 8.4 -1.0 2.7 2.6 2.7 2.9 2.5 1.8 2.3 1.2 -1.8 1.8 2.2 -2.2 1.4
Medication: Gliclazide 2.2 2.5 10.1 1.6 0.8 1.2 1.2 0.3 0.9 3.0 0.6 1.2 -3.2 1.3 2.1 -0.2 1.2
Illnesses of father: None of the above (group 1) 0.4 0.5 2.3 0.6 -0.4 -0.6 -0.5 -0.4 -0.7 -0.9 -0.8 0.5 1.5 -0.1 -1.0 0.2 -0.5
Smoking status: Current 0.3 0.5 2.0 -1.4 0.1 -0.1 0.1 0.5 -0.1 0.6 0.2 0.2 -0.8 0.8 0.1 -0.6 1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.4 0.4 0.6 0.3 0.5 0.5 0.9 -1.1 0.1 -1.0 1.2 -0.2 -0.6 -0.1 -1.1
Whole body water mass 0.2 1.3 6.1 -1.1 -0.0 -1.1 -0.3 -0.4 -1.2 -1.8 -1.3 0.3 2.5 -1.4 -0.6 0.2 -0.0
Leg predicted mass (right) 0.1 0.7 3.3 -1.0 0.6 -0.6 0.3 0.1 -0.5 -1.4 -0.8 0.7 1.8 -1.0 -0.0 0.3 -0.2
Arm fat mass (left) 0.3 1.4 5.0 -0.3 2.1 1.2 1.8 1.2 0.5 -0.6 -0.1 2.2 1.2 0.2 1.0 -1.2 0.4
Number of self-reported non-cancer illnesses 0.4 0.6 1.3 1.0 0.6 0.5 0.6 0.3 1.0 0.6 1.1 0.8 -1.1 0.6 1.0 -0.3 -0.8
Average weekly champagne plus white wine intake 0.5 0.7 1.9 -0.1 -1.2 -1.0 -1.2 -0.9 -0.7 -0.9 -0.3 -0.0 1.4 -0.3 -1.1 0.8 -0.6
Miserableness 0.2 0.4 2.4 1.6 0.0 0.0 -0.0 -0.2 0.4 0.7 0.1 0.2 -1.0 0.5 0.6 0.5 -0.3
Guilty feelings 2.1 3.1 6.6 2.0 1.0 1.5 1.1 1.2 2.5 2.5 2.1 0.4 -2.6 2.0 2.1 0.1 1.0
Wears glasses or contact lenses 1.3 1.5 4.3 -1.3 -0.7 -0.9 -0.8 -1.1 -1.3 -1.3 -0.9 -1.5 0.2 -2.1 -1.5 0.6 -1.8
Ever taken oral contraceptive pill 0.2 0.2 0.9 0.1 -0.9 -0.1 -0.7 -0.4 -0.3 0.2 0.9 0.4 0.2 0.6 0.4 0.4 0.1
Hearing aid user 0.2 0.2 0.6 -0.4 -0.1 0.1 -0.0 -0.7 -0.3 -0.3 -0.5 0.4 0.4 -0.3 0.7 0.5 -0.8
Mother’s age at death 0.6 0.7 1.8 1.3 -0.7 -0.5 -0.7 -0.5 -0.7 -0.8 -0.7 -1.0 -0.0 -0.9 -0.9 1.2 -1.1
Financial situation satisfaction 0.7 0.9 3.2 1.3 0.1 0.5 0.1 0.2 0.5 1.0 0.9 1.8 -0.2 1.5 1.6 -0.7 0.6
Tinnitus: Yes, now most or all of the time 1.9 2.3 4.7 1.0 -1.7 -1.4 -1.7 -1.5 -0.8 -1.6 -1.4 -1.5 1.5 -1.4 -1.0 1.9 -2.2
Commuting to job workplace: Public transport 0.5 0.6 1.8 -0.2 -0.8 -0.6 -0.8 -0.8 -0.7 -0.7 -0.2 -1.4 0.1 -1.0 -1.0 0.4 -0.7
Eye problems/disorders: Glaucoma 0.7 0.9 2.5 0.4 1.0 1.1 1.0 1.0 0.9 1.1 1.1 0.2 -1.6 1.0 0.8 -0.7 0.2
Medication: Blood pressure 1.0 1.9 6.2 -0.9 1.7 1.7 1.7 1.3 0.8 1.5 1.4 0.1 -2.5 0.5 1.0 -1.4 0.9
Pain type(s) experienced in last month: Hip pain 0.4 0.5 1.2 0.4 0.5 0.8 0.5 0.4 0.5 0.8 0.2 0.6 -1.1 0.8 0.9 -0.8 0.7
Supplements: Fish oil (including cod liver oil) 0.7 1.0 2.3 0.6 -1.2 -1.0 -1.2 -1.0 -1.2 -0.2 -0.8 -1.5 -0.3 -1.1 -0.9 0.7 -1.1
High cholesterol (Self-reported) 0.4 0.8 2.3 0.9 0.8 0.8 0.8 0.4 1.0 0.7 0.3 -0.1 -1.2 -0.2 1.2 1.2 -1.5
Medication: Bendroflumethiazide 0.2 0.4 2.1 -1.5 -0.2 0.1 -0.2 -0.4 -0.6 0.2 0.7 -0.8 -0.4 -0.6 -0.4 -0.2 0.4
Medication: Paracetamol 1.5 2.3 3.7 0.3 1.5 1.5 1.5 1.3 1.7 1.9 1.4 1.6 -1.6 1.4 1.9 -1.2 1.8
Medication: Lisinopril 1.3 1.7 3.0 -0.3 1.6 1.5 1.7 1.1 0.4 1.5 0.5 1.5 -1.2 1.0 1.6 -1.3 1.6
Medication: Atorvastatin 0.6 0.7 1.6 0.8 0.8 0.8 0.8 0.7 1.2 0.8 0.9 0.2 -1.0 0.5 1.2 0.9 -0.6
Illnesses of father: High blood pressure 0.4 0.5 2.6 0.8 0.2 0.1 0.3 0.1 0.6 0.3 0.3 -0.5 -0.9 0.8 1.2 -1.6 0.3
Alcohol drinker status: Never 0.3 0.4 2.3 1.5 -0.0 0.2 0.1 -0.2 -0.1 0.7 0.1 0.8 0.2 0.4 0.5 -1.1 0.4
Ever smoked 0.1 0.2 1.5 -0.1 -0.2 -0.8 -0.3 -0.0 0.1 -0.4 0.2 -0.7 0.5 -0.1 0.2 1.2 0.1
Basal metabolic rate 0.2 1.1 5.6 -1.1 0.3 -0.9 -0.1 -0.2 -1.1 -1.7 -1.3 0.7 2.4 -1.3 -0.4 0.0 -0.1
Leg fat percentage (left) 0.5 1.8 7.6 0.2 1.9 1.3 1.8 1.2 0.7 0.0 0.0 2.8 0.8 0.9 1.4 -1.8 0.7
Arm fat-free mass (left) 0.4 1.9 8.4 -1.3 -0.4 -1.4 -0.7 -0.8 -1.7 -2.1 -1.6 0.5 2.9 -1.6 -1.0 0.1 -0.2
Number of operations (self-reported) 0.1 0.1 0.9 0.2 -0.2 0.0 -0.1 0.0 -0.1 -0.1 0.5 -0.2 -0.2 0.1 -0.2 -0.9 -0.1
Average weekly beer plus cider intake 0.2 0.3 3.2 1.8 0.2 0.1 0.2 0.1 0.3 0.5 0.4 0.4 -0.5 0.4 0.2 0.2 -0.6
Irritability 0.8 1.4 3.1 -0.1 0.8 1.2 0.9 1.1 1.4 1.6 1.4 0.6 -1.7 1.5 1.1 -0.5 1.4
Risk taking 0.1 0.1 0.6 -0.6 0.2 0.1 0.2 0.4 -0.0 0.0 0.3 0.1 -0.3 0.4 0.2 -0.8 0.7
Ever had prostate specific antigen (PSA) test 0.6 0.7 3.0 -0.8 0.6 0.3 0.6 0.9 1.1 1.1 0.3 0.1 -0.7 0.7 1.3 -0.3 1.7
Fractured/broken bones in last 5 years 2.5 3.3 7.8 -0.3 -2.1 -2.3 -2.1 -2.0 -2.2 -2.4 -0.8 -1.3 2.8 -0.9 -1.9 -0.5 -1.2
Age started oral contraceptive pill 0.4 0.5 1.7 -0.1 -1.2 -0.6 -1.1 -1.0 -0.9 -0.2 0.4 -0.6 -0.1 -0.6 -1.3 0.2 -0.3
Diastolic blood pressure, automated reading 0.7 2.2 7.2 -1.1 1.0 1.6 1.2 1.3 1.4 1.0 2.7 1.7 -0.4 2.0 0.9 -1.6 1.4
Ever depressed for a whole week 1.1 1.4 4.9 1.3 0.9 1.1 1.0 1.0 1.3 1.6 1.0 0.9 -2.2 1.2 1.3 -0.3 -0.2
Unable to work because of sickness or disability 1.5 2.0 3.7 -0.5 1.9 1.6 1.9 1.8 1.5 1.5 0.6 0.7 -1.1 1.2 1.5 -1.5 1.5
Commuting to job workplace: Cycle 1.3 1.6 4.6 0.8 -2.1 -1.7 -2.0 -1.8 -1.1 -0.3 -0.9 -0.7 0.2 -0.5 -0.7 1.7 -0.9
Myopia 0.3 0.5 1.7 1.3 -0.3 -0.1 -0.3 -0.7 -0.4 -0.5 -1.1 -1.1 -0.2 -0.6 -0.2 0.2 -1.0
Vascular/heart problems diagnosed by doctor 0.8 2.1 4.5 1.3 -2.0 -2.1 -2.0 -1.7 -1.2 -0.9 -1.3 -0.9 1.5 -0.4 -1.0 1.5 -1.1
Cholesterol lowering medication 0.3 0.4 1.6 1.1 0.5 0.8 0.5 0.1 0.6 0.8 1.3 0.3 -0.7 0.6 0.4 -0.1 -0.5
Medication: Omeprazole (e.g. Zanprol) 1.3 1.6 3.5 -0.2 1.3 1.1 1.2 1.3 1.8 1.3 1.9 1.1 -0.9 1.8 1.3 -1.1 0.5
Pain experienced in last month 0.3 0.5 2.2 -0.5 0.3 0.4 0.4 -0.1 -0.4 -0.9 -1.5 -0.5 1.0 -1.5 -0.2 -0.0 0.1
Supplements: Calcium 0.2 0.2 1.0 0.5 -0.2 -0.0 -0.2 -0.3 -0.5 0.2 -0.8 -0.1 0.4 -0.1 -0.1 -0.5 1.0
Basal cell carcinoma (self-reported) 0.2 0.3 1.4 0.1 0.2 0.0 -0.0 -0.3 -0.6 -0.3 -1.1 0.0 0.5 -0.8 -0.4 1.2 0.1
Heart attack/myocardial infarction (self-reported) 1.3 1.7 3.0 -1.7 1.6 1.4 1.4 1.7 1.5 0.8 1.5 1.3 -1.0 0.9 1.1 -0.9 0.8
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 2.4 1.1 1.5 0.9 1.3 0.7 0.8 -0.1 -0.6 1.5 0.8 0.3 0.8 -0.8 -0.5
Heart disease (siblings) 1.8 2.2 3.4 -0.8 1.5 1.5 1.7 1.4 1.7 1.8 1.7 1.1 -1.1 1.3 1.6 -1.6 1.4
Alcohol drinker status: Previous 0.3 0.4 1.8 1.3 0.3 0.3 0.3 0.1 0.4 -0.3 -0.8 -0.2 0.5 -0.7 0.6 0.9 -0.3
Pack years of smoking 0.6 1.0 5.1 -2.2 -0.1 -0.4 -0.3 0.0 -0.1 -0.9 0.2 1.2 2.3 -0.3 -0.9 -0.3 -0.2
Impedance of whole body 0.1 0.5 1.6 -0.8 0.2 1.0 0.4 0.7 1.0 0.6 1.3 -0.2 -1.1 0.5 -0.4 0.1 0.5
Leg fat mass (left) 0.3 1.0 5.1 -0.4 1.5 0.6 1.2 0.7 0.1 -0.7 -0.3 2.3 1.4 0.2 0.8 -1.2 0.3
Arm predicted mass (left) 0.4 1.8 6.9 -1.1 -0.4 -1.5 -0.7 -0.9 -1.7 -2.0 -1.8 0.5 2.6 -1.6 -0.7 0.3 -0.3