Hub : Genes

PEX11A

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0700	0.0250	4.0e-05	0.059	0.050	0.033	0.051	0.042	1.1e-07	8.8e-07	6.4e-05	8.1e-07	7.5e-06
2	GTEx	Colon Transverse	0.2080	0.0710	1.5e-03	0.154	NA	0.109	NA	0.120	8.7e-08	NA	7.3e-06	NA	2.5e-06
3	GTEx	Muscle Skeletal	0.0571	0.0237	2.2e-03	0.039	NA	0.037	NA	0.034	9.3e-05	NA	1.5e-04	NA	2.6e-04
4	YFS	Blood	0.0351	0.0121	1.0e-04	0.022	0.010	0.017	0.013	0.018	6.2e-08	2.0e-04	2.7e-06	2.4e-05	1.1e-06
5	TCGA	Bladder Urothelial Carcinoma	0.0530	0.0290	2.0e-03	0.012	0.033	0.030	NA	0.016	2.9e-02	7.6e-04	1.3e-03	NA	1.5e-02
6	TCGA	Breast Invasive Carcinoma	0.0433	0.0208	5.5e-04	0.015	0.010	0.007	NA	0.012	4.4e-04	2.7e-03	1.0e-02	NA	1.4e-03
7	TCGA	Lung Adenocarcinoma	0.0441	0.0228	2.8e-04	0.033	0.036	0.030	NA	0.034	7.9e-05	4.1e-05	1.9e-04	NA	6.2e-05
8	TCGA	Prostate Adenocarcinoma	0.1790	0.0618	1.7e-10	0.091	0.106	0.101	NA	0.097	9.1e-10	3.6e-11	9.5e-11	NA	2.7e-10

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.7	1.2	5.2	-0.0	-1.1	0.8	-0.8	-2.3	-0.3	-0.8	-1.0
Bipolar Disorder or Schizophrenia	1.1	2.6	6.6	2.4	-1.6	2.6	-1.2	-1.0	-0.8	-1.6	-0.6
Depressed Affect (Nagel 2018)	2.5	5.2	9.6	2.0	-3.1	2.8	-2.5	-2.3	-0.8	-2.7	-0.9
Depression (Nagel 2018)	2.3	3.4	6.8	1.1	-2.6	2.1	-2.4	-1.5	-0.4	-2.5	0.0
Intelligence (Savage-Jansen 2018)	0.5	1.5	3.2	-1.2	1.8	-1.3	1.5	1.3	0.3	1.1	0.4
Neuroticism (Nagel 2018)	1.5	3.6	6.8	2.0	-2.6	2.2	-2.2	-1.6	-0.3	-2.2	-0.5
Schizophrenia (2018)	1.3	2.7	9.4	3.1	-1.1	2.6	-0.9	0.6	-0.8	-1.4	0.0
Schizophrenia vs Biploar Disorder	0.6	0.8	4.0	2.0	-0.0	0.5	0.2	1.2	-0.7	-0.1	-0.0
Worry (Nagel 2018)	1.8	3.9	8.0	1.7	-2.8	2.5	-2.5	-1.9	-0.0	-2.2	0.0
Alzheimer’s Disease (in mother)	0.6	0.7	1.8	-1.4	1.0	-1.1	0.9	0.4	0.5	0.7	0.1
Alzheimer’s Disease (in father)	3.7	4.0	7.4	-2.0	2.7	-2.5	2.2	1.7	0.4	2.5	0.1
Alzheimer’s Disease (including proxy)	2.7	3.9	9.5	-3.1	2.5	-2.4	2.0	0.9	0.5	2.0	0.0
Crohns Disease (2017)	1.2	2.6	4.2	-2.0	2.0	-2.0	1.9	1.2	0.4	1.7	0.9
Irritable Bowel Disease (IBD)	0.9	2.1	4.2	0.3	1.1	-0.5	1.0	2.0	1.8	1.6	2.0
Ulcerative Colitis (UC)	1.1	2.1	4.8	2.2	-0.4	1.1	-0.3	1.4	2.1	0.5	2.0
Major Depression (MDD)	0.4	0.5	1.0	1.0	-0.8	0.5	-1.0	-0.4	0.0	-0.9	-0.0
Reaction Time	0.7	1.2	2.8	1.1	-1.0	1.7	-1.5	0.6	1.0	-0.6	0.9
Verbal and Numeric Reasoning (VNR)	0.5	1.2	2.6	0.3	1.3	-0.7	1.1	1.6	0.9	1.1	1.2
Breast Cancer	1.2	2.8	4.9	1.0	-1.6	1.9	-1.0	-2.2	-1.9	-1.9	-1.5
Ovarian Cancer	0.5	0.6	2.7	0.9	0.4	-0.2	0.3	1.7	0.4	0.6	0.7
Prostate Cancer	0.5	0.7	2.2	1.5	0.5	-1.0	1.2	-0.5	0.5	0.6	-0.0
Age at First Birth	2.4	3.5	7.1	1.9	-2.7	2.7	-2.4	-1.3	0.3	-1.7	0.2
Bipolar Disorder (2011)	2.4	2.3	4.2	0.2	-1.8	1.7	-1.4	-2.0	-0.9	-1.8	-1.2
Body Mass Index (BMI) (2010)	1.0	1.3	2.5	0.1	1.2	-1.1	1.2	1.5	1.1	1.6	0.7
Coronary Artery Disease (CAD)	1.5	1.8	3.7	0.6	-1.5	1.4	-1.1	-1.9	-1.3	-1.6	-0.9
Crohns Disease (2012)	0.3	0.6	2.1	-1.4	0.8	-1.0	0.8	-0.1	-0.4	0.3	-0.1
Mean Putamen Volume	0.7	0.8	3.1	-0.1	0.4	0.1	0.4	-0.5	-1.8	-0.3	-1.5
Fasting Glucose	1.6	1.9	4.6	-1.8	1.3	-2.2	0.9	1.4	0.8	1.4	0.6
HbA1C	1.2	1.3	6.4	0.9	-0.2	-0.5	-0.1	0.1	2.5	0.7	1.6
HDL Cholesterol	1.1	1.8	5.1	0.5	-1.3	0.5	-1.8	0.7	1.7	-0.7	2.3
LDL Cholesterol	0.2	0.4	1.2	-0.5	-0.2	0.0	-0.2	-0.7	-1.1	-0.5	-0.9
Lupus	0.6	0.9	1.9	-0.8	1.1	-1.4	1.2	0.4	0.7	0.9	0.5
Neuroticism (2016)	1.1	1.6	2.9	1.0	-1.5	1.2	-1.7	-0.6	1.2	-1.4	1.1
Primary Biliary Cirrhosis	4.3	6.2	10.7	2.2	-3.3	2.6	-2.8	-2.5	-1.0	-3.2	-1.0
Rheumatoid Arthritis	1.7	2.3	5.0	-1.9	1.9	-2.2	1.7	0.1	-0.4	1.5	-0.9
Schizophrenia (2014)	1.3	2.9	8.6	2.9	-1.2	2.7	-0.6	-0.4	-1.4	-1.7	-0.9
Triglycerides	1.9	3.2	8.5	-0.6	2.5	-2.1	2.9	1.0	-0.1	2.1	-0.4
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.0	-0.8	0.7	-0.8	0.9	-0.2	-1.4	0.5	-0.8
Ulcerative Colitis	2.1	3.1	7.7	2.8	-0.5	0.9	-0.6	1.8	2.4	0.7	2.4
Blood Eosinophil Count	0.4	3.0	6.6	-0.4	1.8	-1.4	1.3	2.6	1.5	2.5	1.4
Blood Platelet Count	0.5	5.3	16.4	-2.8	2.9	-4.1	2.1	1.0	-1.2	1.4	-1.0
Blood Red Count	0.2	2.4	4.2	-0.5	-1.6	2.0	-1.9	-1.9	-1.3	-1.5	-1.1
Blood White Count	0.2	1.6	3.8	1.7	-1.4	0.8	-1.9	0.3	0.5	-1.4	1.1
Heel T-Score	0.8	6.6	11.0	-2.0	2.9	-3.1	2.2	3.2	1.7	3.3	1.2
BMI	0.2	1.2	3.7	0.6	-1.4	1.3	-1.1	-1.9	0.2	-0.7	-0.2
Height	0.8	15.0	31.7	-4.2	5.6	-3.6	5.4	-0.5	-2.5	3.4	-3.4
Waist Hip Ratio (WHR)	1.4	6.1	18.3	0.0	-0.7	0.6	-0.0	-3.1	-4.3	-2.0	-4.0
Systolic Blood Pressure	0.4	2.2	4.9	-1.9	1.6	-1.0	1.7	-0.6	-2.2	0.3	-1.4
Smoking Status	0.2	0.5	1.3	0.2	1.1	0.1	1.1	0.5	-0.1	1.1	-0.2
Allergy or Eczema	0.3	0.8	1.8	-0.2	0.4	-0.7	0.3	1.1	1.3	0.9	1.2
Cardiovascular Disease	0.4	1.2	4.3	-2.1	0.7	-0.9	0.8	-1.1	-1.0	-0.1	-1.0
Hypothyroidism (self reported)	0.6	1.3	4.1	0.3	0.7	-0.7	1.0	-1.1	-1.8	0.5	-2.0
Respiratory disease	0.3	0.7	2.2	1.5	-0.8	0.8	-0.5	-0.8	0.8	-0.1	0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.3	1.1	-0.9	0.2	-0.5	0.4	0.8	0.2	0.9
Lung FEV1/FVC ratio	0.6	2.9	8.8	1.7	-0.6	-0.1	-0.8	1.6	3.0	0.6	2.8
Lung FVC	0.4	2.1	9.7	-3.1	1.0	-2.0	0.0	0.8	0.2	1.2	-0.1
Neuroticism	1.8	4.3	8.3	1.6	-2.9	2.5	-2.9	-1.6	-0.1	-2.6	-0.0
Chronotype (morning person)	1.2	2.8	6.2	1.6	-0.8	1.3	-1.1	2.0	2.5	0.4	2.3
Hair Pigment	0.1	1.9	5.9	1.4	-1.6	2.4	-1.1	-1.1	-0.4	-1.3	-0.3
Tanning	0.1	1.0	3.6	-1.3	1.2	-0.6	0.3	1.9	0.0	0.9	0.5
Hand grip strength (left)	0.6	1.6	3.7	-1.9	1.6	-1.8	1.2	0.5	-0.1	1.4	-0.1
Number of treatments/medications taken	0.3	0.5	2.1	-0.6	0.7	-1.4	0.6	-0.0	-0.5	0.5	-0.4
Average weekly spirits intake	0.2	0.2	1.0	1.0	0.0	0.4	0.2	-0.0	0.6	0.3	0.0
Sensitivity / hurt feelings	0.3	0.5	1.3	0.2	-0.2	0.4	-0.8	0.8	1.1	-0.3	1.1
Frequency of depressed mood in last 2 weeks	3.2	4.5	8.5	1.6	-2.9	2.6	-2.9	-1.3	-0.2	-2.8	0.4
Hearing difficulty/problems: Yes	0.4	0.6	1.4	-0.2	-0.5	0.7	-0.1	-1.0	-1.0	-1.2	-0.9
Relative age of first facial hair	1.7	3.5	8.6	1.9	-1.3	1.1	-1.5	1.6	2.9	-0.0	2.9
Other serious medical condition/disability diagnosed by doctor	1.8	2.3	5.5	1.9	0.3	-0.3	0.4	1.8	2.4	1.2	2.1
Ever used hormone-replacement therapy (HRT)	1.6	2.0	4.7	-1.8	1.4	-2.2	1.5	-0.4	-0.6	1.4	-1.3
Ever had hysterectomy (womb removed)	0.7	0.7	1.8	-0.7	0.8	-1.3	0.8	-0.6	0.5	1.3	-0.5
Systolic blood pressure, automated reading	0.5	1.5	3.2	-1.8	1.6	-1.0	1.4	-0.1	-1.1	1.1	-0.8
Eye problems/disorders: Diabetes related eye disease	1.6	1.7	5.5	0.6	-0.2	0.3	-0.5	1.8	2.4	1.2	1.7
Angina	1.5	2.0	3.0	-0.6	1.5	-1.1	1.3	1.7	1.5	1.6	1.6
Medication for hormone replacement therapy	2.4	2.7	7.1	-1.4	1.7	-2.7	1.9	0.2	0.8	2.3	0.1
Vitamin and mineral supplements	0.4	0.6	1.3	-0.9	-1.0	0.3	-0.9	-1.1	-0.2	-0.9	0.0
Supplements: Zinc	1.9	2.1	3.6	-1.2	1.9	-1.0	1.8	-0.1	-1.5	1.4	-1.7
Medication: Co-codamol	0.6	0.6	1.3	-0.4	-0.7	0.3	-0.6	-1.0	-1.0	-0.9	-1.1
Medication: Metformin	0.9	1.3	3.4	0.8	-1.5	1.4	-1.9	0.6	0.3	-0.7	1.1
Diabetes (father)	0.5	0.6	1.8	1.3	-0.6	0.2	-0.6	0.4	1.1	0.2	0.9
Diabetes (mother)	1.1	1.5	4.2	-0.3	-1.8	0.9	-1.4	-2.0	0.1	-1.1	-0.1
Severe depression (siblings)	0.5	0.6	1.4	0.4	-0.9	0.7	-0.6	-0.4	1.0	-0.7	1.2
Pack years adult smoking proportion	1.7	2.7	7.3	-2.7	1.6	-2.6	1.3	0.2	1.0	1.3	0.7
Impedance of leg (right)	0.1	0.6	1.7	0.5	1.0	-0.6	1.0	1.3	-0.1	0.6	0.1
Leg fat-free mass (left)	0.3	1.7	3.4	-1.8	0.7	-0.3	0.8	-1.8	-1.4	0.2	-1.8
Trunk fat percentage	0.1	0.3	1.0	-0.5	0.2	-0.6	0.2	-1.0	-0.5	0.4	-0.6
Hand grip strength (right)	0.5	1.2	2.7	-1.5	1.2	-1.6	0.8	0.9	0.5	1.2	0.7
Townsend deprivation index at recruitment	0.7	1.0	1.9	-0.8	-0.7	0.4	-0.5	-1.4	-1.3	-1.4	-1.1
Current tobacco smoking	1.1	1.8	4.1	-0.6	1.8	-1.9	2.0	0.4	0.3	1.6	0.1
Average weekly fortified wine intake	2.2	2.6	5.4	1.9	-1.9	2.3	-1.6	-1.1	0.3	-2.0	0.5
Maternal smoking around birth	0.3	0.4	1.0	-0.4	-0.6	0.2	-0.6	-1.0	-0.4	-1.0	-0.2
Fed-up feelings	1.1	2.1	4.1	0.1	-1.9	1.3	-1.5	-2.0	-0.8	-1.9	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	4.2	0.6	-1.9	1.9	-2.0	-1.4	-1.1	-2.1	-0.8
Relative age voice broke	0.9	1.3	3.0	1.2	-0.8	1.4	-0.7	0.5	1.7	0.1	1.7
Taking other prescription medications	0.7	1.1	2.1	1.3	-1.3	0.8	-1.5	-0.1	-0.9	-1.4	-0.1
Age when periods started (menarche)	0.4	1.0	3.0	-0.3	0.8	-1.1	0.6	1.7	0.6	0.9	1.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.6	0.1	0.3	0.1	0.1	1.3	0.6	1.2	0.6
Heel bone mineral density (BMD) T-score, automated (left)	2.1	4.9	9.6	-1.2	3.1	-2.5	2.8	2.2	1.4	2.6	0.8
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.1	-0.0	0.2	0.4	0.3	0.5	-0.0	1.1	0.1
Qualifications: CSEs or equivalent	0.8	1.0	4.0	0.4	-1.1	0.4	-1.0	-2.0	-0.4	-1.0	-0.6
Serious illness, injury or assault to yourself	0.9	1.1	2.8	0.8	1.5	-1.1	1.7	0.6	0.4	1.3	0.2
High blood pressure	0.6	1.6	3.2	-1.8	1.2	-1.4	1.3	-0.7	-1.5	0.4	-1.4
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.5	0.1	0.1	-0.3	-0.1	1.0	1.2	0.4	1.2
Multivitamins +/- minerals	0.8	1.0	2.3	0.9	1.4	-0.4	1.0	1.5	0.2	1.2	-0.1
Stomach or abdominal pain in last month	2.7	3.4	8.8	-0.4	-0.4	0.3	0.1	-2.5	-3.0	-1.8	-3.0
Supplements: Glucosamine	0.1	0.1	0.6	0.8	-0.1	-0.0	-0.3	0.3	-0.3	-0.4	-0.2
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	4.3	2.1	-0.2	0.4	0.0	-0.6	-0.5	-0.1	-0.7
Medication: Atenolol	0.2	0.2	1.3	-1.2	0.5	-0.3	0.1	-0.0	-0.3	0.0	0.1
Medication: Levothyroxine sodium	1.0	1.7	3.6	1.9	1.2	-0.6	1.5	1.5	0.6	1.7	0.3
Sitting height	0.3	2.4	5.0	-2.0	2.2	-1.1	2.2	0.4	-0.1	1.9	-0.6
Chronic bronchitis/emphysema (father)	0.8	0.9	1.9	-1.4	-0.3	-0.5	0.0	-1.4	-1.1	-0.4	-1.3
High blood pressure (mother)	1.5	2.1	4.8	0.7	-1.9	1.4	-1.8	-0.7	-1.3	-2.2	-0.7
Body mass index (BMI)	0.1	0.3	2.1	0.1	-0.3	0.0	-0.1	-1.4	-0.2	0.2	-0.5
Impedance of leg (left)	0.1	0.5	1.0	-0.2	1.0	-1.0	0.9	0.9	-0.2	0.7	0.0
Leg predicted mass (left)	0.3	1.7	3.5	-1.8	0.7	-0.3	0.8	-1.9	-1.5	0.1	-1.9
Trunk fat mass	0.2	0.8	2.1	-1.0	0.6	-0.7	0.7	-1.5	-0.9	0.5	-1.1
Waist circumference	0.6	2.2	7.3	-0.6	-0.1	-0.1	0.3	-2.7	-2.0	-0.3	-2.4
Number of incorrect matches in round	0.3	0.4	1.6	-0.3	-0.6	0.3	-1.3	0.6	0.2	-0.8	0.5
Past tobacco smoking	0.2	0.4	0.9	-0.3	-0.7	-0.9	-0.5	-0.8	0.1	-0.8	0.3
Alcohol usually taken with meals	1.4	2.3	5.8	0.1	1.0	-0.8	0.8	2.4	2.0	1.5	1.9
Nervous feelings	2.2	4.2	8.8	1.5	-3.0	2.7	-2.7	-1.4	-0.3	-2.4	-0.1
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.1	6.0	2.0	-2.4	2.5	-2.4	-0.5	0.9	-1.3	0.7
Hearing difficulty/problems with background noise	0.3	0.5	2.0	0.2	-0.0	1.4	0.1	-0.1	-0.6	-0.3	-1.2
Hair/balding pattern: Pattern 2	3.4	4.3	8.1	1.2	-2.0	2.2	-1.7	-2.1	-2.5	-2.8	-1.6
Had menopause	1.8	2.3	5.1	-2.3	1.7	-2.1	1.5	0.0	-0.2	1.7	-0.9
Had other major operations	0.4	0.5	1.2	-0.6	0.5	-1.1	0.3	-0.5	-0.9	0.0	-1.1
Forced vital capacity (FVC)	0.4	1.7	8.2	-2.9	0.6	-1.6	0.3	-0.8	-0.8	0.0	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.6	5.5	-0.8	2.3	-2.3	1.9	2.2	1.6	2.2	1.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.5	0.2	-1.1	0.4	-1.2	-0.8	0.3	-1.0	0.3
Qualifications: None of the above	0.8	1.7	4.5	0.4	-1.6	2.1	-1.5	-0.8	-0.9	-1.4	-0.6
Financial difficulties in last 2 years	0.1	0.2	0.6	-0.2	-0.1	0.1	-0.4	-0.1	0.8	-0.1	0.7
Mouth/teeth dental problems	0.6	0.9	1.7	0.9	0.5	-1.3	0.7	0.8	1.2	0.9	1.1
Heart attack	1.7	2.1	3.8	-1.9	1.2	-2.0	1.0	0.6	1.8	1.6	1.1
Allergy	0.3	0.6	1.1	-1.0	0.6	-0.8	0.6	-0.4	-1.0	0.4	-1.0
Pain all over the body in last month	2.3	2.5	4.5	1.3	-1.7	1.6	-1.8	-1.4	-1.4	-2.1	-1.0
Diabetes (self-reported)	0.6	0.9	1.7	1.1	-0.3	-0.1	-0.5	1.3	1.1	0.9	1.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	1.0	-1.0	0.9	-0.4	0.7	0.2	-0.5	0.4	-0.0
Medication: Ramipril	0.5	0.6	2.2	-1.5	0.2	-1.5	0.1	-0.8	0.1	0.3	-0.2
Medication: Simvastatin	0.6	0.8	1.9	-0.3	-1.1	0.4	-1.4	0.2	0.8	-1.0	1.2
Fluid intelligence score	0.6	1.3	4.4	0.1	1.0	-0.6	0.5	2.1	1.1	0.7	1.6
Illnesses of siblings	0.4	0.5	1.6	0.3	0.9	-0.1	0.7	1.3	0.6	0.5	0.8
Neuroticism score	1.5	3.1	6.2	1.0	-2.4	2.4	-2.5	-1.1	-0.3	-2.1	-0.2
Weight	0.4	1.7	3.9	-1.5	0.9	-0.8	1.2	-2.0	-1.2	0.7	-1.7
Impedance of arm (right)	0.1	0.4	2.0	0.2	0.5	-0.3	0.1	1.4	-0.1	0.1	0.6
Arm fat percentage (right)	0.1	0.4	1.9	0.5	-0.3	0.2	-0.3	-1.4	-0.5	-0.1	-0.6
Trunk fat-free mass	0.5	3.1	6.0	-2.3	1.5	-0.6	1.7	-1.9	-2.1	0.3	-2.5
Hip circumference	0.2	0.9	3.2	-0.9	0.6	-0.9	0.9	-1.8	-0.3	0.8	-0.8
Time employed in main current job	0.1	0.1	0.3	0.5	-0.1	0.1	-0.2	0.1	-0.3	-0.2	0.1
Alcohol intake versus 10 years previously	0.6	0.9	2.2	0.1	-1.0	1.1	-1.2	0.2	1.1	-0.7	1.5
Father’s age at death	0.8	1.0	5.1	2.3	-0.8	1.4	-0.4	0.1	0.1	-0.5	0.1
Worrier / anxious feelings	0.9	1.7	3.9	1.3	-1.8	1.6	-2.0	-0.6	0.3	-1.3	0.3
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	4.1	0.1	-1.1	0.7	-1.0	-1.5	-2.0	-1.5	-1.3
Falls in the last year	0.1	0.1	0.4	0.2	-0.4	0.3	-0.5	0.0	-0.2	-0.7	-0.4
Hair/balding pattern: Pattern 3	0.5	0.7	2.4	0.6	0.3	0.3	0.5	1.6	0.8	1.0	0.7
Number of live births	2.0	2.9	5.9	-0.9	2.4	-2.3	2.2	0.9	-1.0	1.8	-1.1
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	6.3	-2.5	0.1	-1.5	-0.3	-0.3	0.2	0.1	0.1
Pulse rate	1.7	2.9	6.0	-1.3	2.1	-2.0	2.2	1.3	0.9	2.5	0.3
Happiness	3.2	3.9	7.8	0.5	-2.6	2.0	-2.0	-2.2	-1.2	-2.8	-1.3
Noisy workplace	0.6	0.8	2.1	-0.1	-0.7	0.6	-0.6	-1.5	-0.9	-0.7	-1.3
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.2	0.2	-0.6	0.0	-0.5	-0.0	0.3	-1.1	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.4	-1.5	1.0	-1.6	1.1	-0.2	0.1	0.3	0.0
Mouth/teeth dental problems: Dentures	0.1	0.1	0.8	-0.2	-0.0	0.9	-0.2	0.3	0.2	0.2	0.2
Asthma	0.3	0.5	1.4	1.2	-0.7	1.0	-0.2	-0.7	-0.3	-0.8	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.3	-1.5	0.3	-0.6	0.4	-0.3	-1.0	-0.2	-0.8
Medication: Cholesterol lowering	0.8	1.2	3.4	-0.1	-1.3	0.4	-1.6	0.6	1.1	-0.6	1.8
Depression (self-reported)	1.8	2.2	4.8	1.2	-2.1	1.1	-2.2	-1.3	0.3	-1.9	0.7
Medication: Lansoprazole	1.1	1.3	3.9	-1.2	1.2	-2.0	1.1	1.1	-0.0	1.0	0.5
Prospective memory result	0.1	0.1	0.1	-0.1	-0.1	-0.4	-0.2	0.2	0.3	0.3	0.3
Lung cancer (father)	0.8	1.0	3.2	0.5	-0.6	0.4	-0.5	-0.7	-1.7	-0.4	-1.8
Illnesses of mother	0.6	0.8	2.0	0.1	0.4	0.1	-0.0	1.4	1.4	0.6	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	6.6	-2.6	-0.1	-1.3	-0.7	-0.3	0.2	-0.2	0.2
Pulse wave Arterial Stiffness index	0.4	0.5	1.0	1.0	-0.7	0.5	-0.6	-0.9	-0.7	-0.1	-0.6
Impedance of arm (left)	0.0	0.2	0.9	-0.4	0.3	-0.6	-0.1	0.9	-0.1	0.0	0.5
Arm fat mass (right)	0.2	0.7	3.2	-0.5	0.3	-0.2	0.4	-1.8	-0.9	0.3	-1.2
Trunk predicted mass	0.5	3.0	5.6	-2.3	1.5	-0.6	1.6	-1.8	-2.0	0.3	-2.4
Standing height	0.6	6.3	13.4	-3.7	2.8	-1.8	2.8	-1.4	-2.4	1.2	-3.0
Length of working week for main job	0.6	0.7	1.4	0.2	-1.0	0.7	-1.2	-0.0	1.1	-0.6	1.1
Exposure to tobacco smoke at home	0.5	0.6	1.5	0.8	0.4	-0.5	0.4	0.5	1.2	1.2	0.7
Breastfed as a baby	0.4	0.5	1.3	0.8	0.7	0.3	1.1	0.5	-0.1	1.1	-0.5
Tense / ‘highly strung’	0.6	1.0	2.2	-0.0	-1.5	0.9	-1.1	-1.4	-0.3	-1.3	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.9	4.5	2.1	-1.6	1.3	-1.5	-1.7	0.3	-1.1	0.3
Hair/balding pattern: Pattern 4	0.4	1.0	1.8	1.1	-1.2	1.3	-1.1	-0.9	0.2	-1.4	-0.2
Birth weight of first child	0.6	1.0	2.9	0.1	0.6	0.5	1.3	-1.5	-0.7	0.7	-1.7
Peak expiratory flow (PEF)	0.3	0.6	2.1	-1.5	0.3	-1.0	0.0	-0.4	0.8	0.9	0.4
Pulse wave reflection index	1.2	1.5	3.8	1.9	-1.2	1.4	-1.0	-0.7	-1.2	-1.1	-0.7
Ever highly irritable/argumentative for 2 days	0.9	1.0	2.6	-1.6	1.2	-1.3	1.1	0.5	0.4	1.1	-0.1
Loud music exposure frequency	0.2	0.2	1.0	0.2	0.1	-0.4	-0.0	1.0	0.3	0.1	0.3
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	1.8	-0.7	0.6	-0.9	0.5	0.6	1.4	0.8	1.1
Mouth/teeth dental problems: Bleeding gums	2.5	3.2	7.5	-0.2	-1.4	1.0	-0.9	-2.7	-2.2	-2.4	-1.9
Blood clot in the leg (DVT)	1.5	1.9	4.4	0.5	-1.9	2.1	-1.8	-0.6	0.6	-1.6	0.8
Medication: Paracetamol	0.1	0.2	0.4	-0.7	0.2	-0.4	0.4	-0.4	-0.1	0.6	-0.4
Headache pain in last month	1.3	2.2	5.0	1.0	-2.1	1.0	-2.2	-0.8	-0.9	-2.1	-0.4
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.9	0.1	0.2	-0.2	0.2	-0.7	-0.5	-0.1	-0.9
Glaucoma (self-reported)	2.1	2.5	4.8	-0.5	-1.2	1.0	-1.1	-2.0	-2.2	-1.9	-1.9
Gout (self-reported)	0.3	0.5	1.8	-0.2	-0.1	-0.2	0.2	-1.4	-1.0	-0.2	-0.8
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	3.2	0.7	1.6	-1.3	1.6	1.1	-0.5	1.8	-0.5
Medication: Amlodipine	0.1	0.1	0.4	0.3	0.5	-0.1	0.6	0.5	-0.1	0.2	0.3
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.5	1.2	0.7	-0.2	1.2	0.4	0.0	1.0	-0.3
Birth weight	0.6	1.3	3.7	-0.9	-0.2	0.2	-0.2	-1.7	-1.5	-0.5	-1.9
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.1	0.0	0.1	0.1	0.3	-0.1	0.3	0.1	-0.0
High blood pressure (siblings)	0.2	0.4	1.0	-0.5	-0.4	-0.1	-0.1	-0.8	-0.8	-0.2	-1.0
Forced vital capacity (FVC), Best measure	0.4	1.5	8.7	-3.0	0.3	-1.2	-0.2	-0.7	-0.7	-0.2	-0.7
Body fat percentage	0.1	0.2	1.1	-0.1	0.0	-0.4	0.1	-1.1	-0.2	0.4	-0.3
Leg fat percentage (right)	0.0	0.2	0.6	0.6	0.1	-0.1	0.3	-0.8	-0.1	0.5	-0.2
Arm fat-free mass (right)	0.6	2.8	6.3	-2.5	1.1	-0.7	1.3	-2.2	-1.6	0.3	-2.3
Exposure to tobacco smoke outside home	0.4	0.5	1.9	0.2	0.3	-0.7	0.6	-0.4	1.1	1.4	0.0
Comparative body size at age 10	0.9	2.4	8.2	2.9	-1.9	1.0	-1.9	-0.5	-0.0	-1.6	0.6
Number of full brothers	1.0	1.2	3.3	0.0	1.7	-1.0	1.2	1.8	-0.2	1.1	0.2
Worry too long after embarrassment	0.3	0.5	2.7	1.6	-0.6	0.4	-0.6	-0.2	-0.3	-0.7	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.3	0.3	-1.0	0.6	-1.1	-0.5	0.5	-0.9	0.6
Wheeze or whistling in the chest in last year	0.1	0.2	1.1	0.7	0.4	-0.0	0.2	1.1	-0.1	0.1	0.0
Number of children fathered	0.3	0.3	1.7	-0.2	0.4	0.3	0.0	1.3	0.4	0.2	0.5
Reason for reducing amount of alcohol drunk: Health precaution	3.3	3.9	7.2	-0.2	1.9	-1.8	1.6	2.7	2.2	2.5	1.9
Age at first live birth	1.3	2.4	4.6	1.6	-2.0	1.6	-2.1	-0.2	1.0	-1.6	1.2
Pulse wave peak to peak time	0.5	0.5	1.5	-1.2	0.8	-0.6	0.7	0.8	0.6	0.2	0.4
Health satisfaction	0.5	0.7	1.9	-0.6	-0.4	-0.2	-0.1	-0.8	-1.3	-0.8	-1.4
Shortness of breath walking on level ground	0.2	0.3	0.9	-0.5	0.2	-0.7	0.0	-0.0	-0.9	-0.0	-0.8
Qualifications: College or University degree	0.3	0.8	2.2	1.5	-0.9	0.8	-0.7	0.0	0.1	-1.3	0.8
Eye problems/disorders: None of the above	0.1	0.2	0.4	0.4	0.4	0.2	0.7	0.4	0.5	-0.1	0.3
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.5	-1.1	0.2	-0.4	0.4	0.7	1.2	0.2	1.0
Emphysema/chronic bronchitis	0.5	0.6	1.7	1.3	-0.7	1.2	-0.7	-0.4	-0.0	-0.6	0.1
Medication for pain relief, constipation, heartburn	0.8	1.4	3.4	1.8	-1.0	1.6	-1.0	-0.8	-0.7	-1.3	-0.6
Neck or shoulder pain in last month	0.4	0.5	0.8	-0.8	0.9	-0.8	0.7	0.6	-0.7	0.7	-0.8
Medication: Blood pressure	0.1	0.2	1.0	-0.5	0.4	-0.1	0.5	-0.0	-1.0	0.2	-0.4
Angina (self-reported)	1.0	1.4	2.0	-0.5	1.4	-0.9	1.3	1.4	1.0	1.4	1.1
Migraine (self-reported)	1.3	1.6	3.7	-0.2	-1.4	1.4	-1.9	-0.5	-1.1	-1.8	-0.4
Medication: Ibuprofen	0.8	1.0	3.0	-1.7	1.0	-1.2	0.9	0.0	-0.8	0.6	-0.8
Medication: Allopurinol	0.2	0.3	1.0	-0.2	0.3	-0.7	0.3	0.1	0.6	0.7	1.0
Medication: Omeprazole	0.7	0.8	1.9	0.3	-1.3	0.2	-1.4	-1.1	0.3	-1.2	0.2
Medication: Seretide 50 evohaler	0.1	0.1	0.2	-0.5	-0.4	-0.1	-0.2	-0.2	0.1	-0.1	0.5
Mean time to correctly identify matches	0.3	0.6	1.2	0.9	-0.3	1.1	-0.6	0.7	1.0	-0.0	0.8
Heart disease (mother)	0.5	0.6	1.2	-0.8	-0.0	-0.4	0.1	-1.0	-1.1	-0.5	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	3.4	1.8	0.0	0.2	-0.0	1.2	1.1	0.4	1.2
Whole body fat mass	0.2	0.7	2.3	-0.8	0.4	-0.5	0.5	-1.5	-0.6	0.5	-1.0
Leg fat mass (right)	0.1	0.5	1.6	-0.3	0.5	-0.4	0.7	-1.2	-0.5	0.7	-0.9
Arm predicted mass (right)	0.5	2.4	5.0	-2.2	1.0	-0.6	1.2	-2.2	-1.5	0.3	-2.1
Pulse rate, automated reading	1.9	6.2	12.0	-1.9	3.0	-3.1	2.8	2.1	1.5	3.5	1.0
Alcohol intake frequency.	0.2	0.6	1.5	0.1	-0.7	0.4	-0.8	0.8	1.0	-0.2	1.2
Comparative height size at age 10	0.2	1.4	4.0	-2.0	1.3	-0.7	1.1	-1.1	-1.0	0.4	-1.0
Number of full sisters	0.2	0.3	1.0	-0.3	0.3	0.0	0.5	-0.3	-1.0	-0.2	-0.8
Suffer from ‘nerves’	3.7	5.8	12.0	2.1	-3.5	3.1	-3.2	-1.9	0.1	-2.7	0.3
Overall health rating	0.3	0.6	2.0	0.3	0.3	-0.4	0.5	-0.9	-1.4	-0.1	-1.2
Chest pain or discomfort	0.4	0.5	1.3	0.4	-0.9	1.2	-0.9	-0.9	0.3	-0.5	-0.0
Had major operations	0.1	0.1	0.6	-0.0	-0.0	-0.8	0.3	-0.1	0.1	0.2	0.1
Age at last live birth	0.7	1.1	2.4	1.2	-1.3	1.1	-1.5	-0.3	0.4	-1.1	0.5
Family relationship satisfaction	1.3	1.6	3.7	0.8	-1.9	1.4	-1.6	-1.1	-0.1	-1.7	-0.4
Leg pain on walking	1.2	1.5	4.6	-0.5	-0.7	0.6	-0.8	-1.3	-1.8	-0.7	-2.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.3	0.4	-0.6	0.2	-1.1	1.0	0.8	-0.2	0.9
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.8	-0.1	-0.6	0.9	-0.7	-0.5	0.3	-0.2	0.4
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	3.6	0.8	-1.4	1.9	-1.7	-0.0	-1.2	-1.3	-0.7
Medication: Aspirin	2.0	2.6	4.7	-0.9	1.5	-1.3	1.0	2.2	1.9	1.8	1.8
Supplements: Vitamin C	0.3	0.3	0.8	-0.1	-0.7	0.9	-0.6	-0.6	0.3	-0.6	0.4
Knee pain experienced in last month	0.6	1.0	2.8	-1.7	-0.1	-0.0	-0.7	-0.5	-1.4	-1.2	-0.8
Hypertension (Self-reported)	0.7	1.9	3.4	-1.8	1.0	-1.3	1.2	-1.2	-1.6	0.3	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.4	-0.5	-0.3	0.1	-0.6	0.2	0.2	-0.0	0.5
Illnesses of father: Heart disease	0.0	0.0	0.1	-0.2	-0.1	-0.0	-0.0	-0.3	0.2	-0.3	0.0
Illnesses of siblings: Diabetes	0.2	0.3	0.7	0.3	-0.3	-0.0	-0.1	-0.9	-0.7	-0.2	-0.8
Smoking status: Previous	0.2	0.3	0.9	-0.2	0.5	1.0	0.2	0.2	-0.6	0.3	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	2.2	-1.5	1.1	-0.6	1.3	-0.9	-1.4	-0.0	-1.4
Whole body fat-free mass	0.4	2.5	5.2	-2.1	1.1	-0.3	1.2	-2.0	-1.8	0.2	-2.3
Leg fat-free mass (right)	0.4	2.0	4.8	-2.1	0.6	-0.3	0.6	-2.2	-1.5	0.0	-1.9
Arm fat percentage (left)	0.1	0.4	2.3	0.2	-0.4	-0.0	-0.4	-1.5	-0.4	-0.1	-0.5
Average weekly red wine intake	0.2	0.3	0.9	-0.2	0.6	-0.9	0.8	-0.5	0.1	0.2	0.2
Handedness (chirality/laterality): Left-handed	1.3	1.5	5.0	2.2	-1.1	2.0	-0.4	0.2	1.0	-0.5	0.8
Mood swings	1.2	2.2	4.5	1.0	-2.1	2.1	-2.1	-0.6	0.7	-1.4	0.4
Loneliness, isolation	0.7	1.0	1.7	1.3	-1.1	0.8	-1.1	-0.9	-0.5	-1.3	-0.8
Long-standing illness, disability or infirmity	0.5	0.8	1.6	1.1	-1.0	0.5	-1.1	0.4	0.7	-0.6	1.3
Ever had bowel cancer screening	0.5	0.6	2.1	1.4	-0.2	0.9	-0.2	-0.7	-0.4	-0.9	-0.2
Diabetes diagnosed by doctor	1.0	1.7	3.2	1.8	-1.4	0.6	-1.2	0.8	1.7	0.2	1.7
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	3.5	0.3	-1.0	0.8	-0.4	-1.9	-0.8	-1.1	-1.1
Friendships satisfaction	0.9	1.1	2.3	0.1	-1.5	1.4	-1.2	-1.2	0.3	-1.3	-0.3
Qualifications: nursing, teaching	0.5	0.7	2.4	-1.6	-0.0	-1.1	0.0	-0.8	-0.7	-0.9	-0.2
Commuting to job workplace: Walk	0.5	0.5	1.5	1.0	-0.5	1.2	-0.4	0.8	-0.1	-0.9	-0.1
Eye problems/disorders: Cataract	0.2	0.2	1.1	-0.4	0.1	-1.1	0.0	0.3	-0.1	0.6	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.8	0.1	0.2	0.9	-0.3	0.8	-0.2	0.5	-0.4
Medication for cholesterol	1.8	2.7	4.6	2.2	-1.6	2.1	-1.8	1.0	1.2	-1.0	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	3.0	-0.3	0.3	-0.3	0.4	0.8	1.7	0.6	1.7
Back pain experienced in last month	0.1	0.1	0.4	0.2	0.1	-0.1	0.2	-0.3	0.1	0.6	-0.5
Mineral and other dietary supplements	0.3	0.4	1.0	-1.0	0.4	-1.0	0.7	-0.1	0.3	0.6	0.5
Breast cancer (self-reported)	0.5	0.6	4.5	2.1	0.2	0.2	0.2	0.1	0.2	-0.0	0.2
Asthma (self-reported)	0.3	0.6	1.9	1.4	-0.8	1.1	-0.4	-0.5	-0.4	-0.8	-0.3
Osteoporosis (self-reported)	0.2	0.3	1.9	1.4	-0.2	0.3	0.0	-0.2	0.3	-0.3	-0.2
Osteoarthritis (self-reported)	1.7	2.3	6.1	0.5	-0.8	0.2	-0.2	-2.1	-2.5	-1.3	-2.2
Medication: Aspirin	1.5	2.0	3.6	-0.8	1.1	-1.0	0.7	1.9	1.9	1.6	1.6
Medication: Gliclazide	1.5	1.7	5.6	2.4	-1.7	1.5	-1.2	-0.6	-0.6	-0.9	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.3	0.5	0.7	-0.4	0.7	-0.4	0.5	0.2	0.2	0.6
Smoking status: Current	0.8	1.3	3.2	0.0	1.6	-1.5	1.8	0.5	0.0	1.5	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.6	-0.9	-0.8	-0.2	-1.6	0.5	1.2	0.1	1.3
Whole body water mass	0.4	2.4	4.9	-2.1	1.0	-0.3	1.2	-2.1	-1.7	0.2	-2.2
Leg predicted mass (right)	0.4	1.9	4.9	-2.0	0.5	-0.3	0.5	-2.2	-1.5	-0.0	-1.9
Arm fat mass (left)	0.3	1.1	3.9	-0.9	0.4	-0.5	0.6	-2.0	-1.1	0.4	-1.5
Number of self-reported non-cancer illnesses	0.5	0.9	2.5	0.7	-1.2	0.7	-1.2	-0.4	-0.7	-1.6	0.4
Average weekly champagne plus white wine intake	0.3	0.4	2.1	-1.5	0.1	-0.4	-0.1	-0.5	-0.6	0.2	-0.8
Miserableness	1.0	1.7	3.2	0.9	-1.8	1.7	-1.5	-1.4	-0.2	-1.6	-0.3
Guilty feelings	1.6	2.4	5.0	2.0	-1.9	2.2	-1.9	0.0	0.1	-1.6	0.3
Wears glasses or contact lenses	1.0	1.1	3.0	0.1	1.3	-0.9	1.0	1.2	0.7	1.7	0.8
Ever taken oral contraceptive pill	0.4	0.4	1.5	-1.2	-0.2	-0.6	0.1	-0.4	-0.8	-0.6	-0.3
Hearing aid user	0.2	0.2	0.8	0.1	0.2	-0.2	0.3	-0.1	0.7	0.4	0.9
Mother’s age at death	0.5	0.7	1.6	0.3	-0.9	1.0	-0.8	-0.7	-0.7	-1.2	-0.6
Financial situation satisfaction	1.2	1.5	2.7	0.5	-1.6	1.0	-1.2	-1.5	-1.1	-1.6	-0.9
Tinnitus: Yes, now most or all of the time	0.9	1.1	2.0	1.4	-0.9	1.2	-0.9	0.7	1.4	-0.3	1.1
Commuting to job workplace: Public transport	0.3	0.4	1.0	-0.5	0.4	-0.7	0.4	-0.4	-1.0	0.1	-0.9
Eye problems/disorders: Glaucoma	1.4	1.7	3.3	-0.4	-1.1	0.9	-1.1	-1.4	-1.8	-1.6	-1.3
Medication: Blood pressure	0.6	1.1	2.2	-1.5	0.9	-1.3	0.9	-0.9	-1.0	0.1	-1.1
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.7	0.3	-0.6	0.8	-0.6	-0.4	0.0	-0.0	-0.4
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.9	0.4	-0.0	0.7	-0.4	0.9	0.7	0.0	0.8
High cholesterol (Self-reported)	0.8	1.4	3.7	-0.0	-1.6	1.2	-1.9	-0.4	-0.3	-1.9	0.5
Medication: Bendroflumethiazide	1.7	2.6	4.7	-2.2	1.6	-1.7	1.7	-0.8	-1.9	0.5	-1.9
Medication: Paracetamol	0.0	0.1	0.3	-0.0	-0.3	0.1	-0.1	-0.2	0.2	0.5	-0.2
Medication: Lisinopril	1.0	1.3	4.1	-0.2	0.4	-0.6	0.9	-1.4	-2.0	-0.2	-1.9
Medication: Atorvastatin	0.6	0.8	2.0	0.1	-1.2	1.4	-1.4	-0.2	0.1	-0.9	0.5
Illnesses of father: High blood pressure	0.5	0.6	1.3	0.3	-0.9	0.9	-0.7	-1.1	0.1	-0.9	-0.2
Alcohol drinker status: Never	0.7	0.8	2.2	1.5	-0.9	1.5	-0.8	0.4	0.4	-0.6	0.3
Ever smoked	0.4	0.7	1.9	0.0	0.6	0.8	0.3	1.4	1.0	1.1	0.7
Basal metabolic rate	0.4	2.4	4.8	-2.0	1.0	-0.4	1.2	-2.1	-1.8	0.2	-2.2
Leg fat percentage (left)	0.1	0.2	0.9	0.3	0.0	-0.3	0.2	-0.9	0.0	0.6	-0.2
Arm fat-free mass (left)	0.5	2.4	4.5	-2.1	1.2	-0.6	1.4	-2.0	-1.5	0.5	-2.1
Number of operations (self-reported)	0.1	0.2	0.8	-0.2	0.3	-0.5	0.3	-0.9	-0.1	0.1	-0.5
Average weekly beer plus cider intake	1.3	1.9	3.5	-0.5	-1.1	1.4	-1.2	-1.4	-1.7	-1.9	-1.4
Irritability	0.5	0.8	2.0	-1.1	-0.8	0.7	-0.6	-1.4	-0.5	-0.8	-0.9
Risk taking	0.8	1.2	2.1	-1.4	1.4	-1.4	1.4	0.4	-0.1	1.0	-0.7
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.6	1.1	0.4	-0.5	0.5	1.5	1.6	1.2	1.2
Fractured/broken bones in last 5 years	0.4	0.6	1.7	0.5	0.9	-1.3	1.0	0.1	0.1	0.8	-0.3
Age started oral contraceptive pill	0.2	0.2	0.8	0.5	0.5	-0.2	0.3	0.4	-0.1	0.9	-0.6
Diastolic blood pressure, automated reading	0.7	2.2	7.3	-2.7	0.8	-0.6	0.5	-1.1	-2.1	0.3	-1.9
Ever depressed for a whole week	1.3	1.7	4.1	1.7	-1.4	2.0	-1.4	-0.3	0.6	-1.3	0.7
Unable to work because of sickness or disability	0.3	0.4	0.9	0.6	0.1	-0.5	0.0	0.5	1.0	0.6	0.8
Commuting to job workplace: Cycle	1.1	1.4	3.5	0.7	-1.9	1.3	-1.7	-0.7	0.6	-1.1	0.5
Myopia	0.4	0.6	1.9	1.4	-0.8	0.8	-0.6	-0.7	-0.1	-1.0	0.2
Vascular/heart problems diagnosed by doctor	0.6	1.6	3.3	1.8	-1.5	1.7	-1.5	0.4	0.7	-0.9	0.8
Cholesterol lowering medication	1.1	1.6	2.9	-0.0	-0.9	1.1	-0.9	-1.7	-1.5	-1.6	-1.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.6	-0.0	-0.7	-0.2	-0.8	-0.6	0.5	-0.3	0.2
Pain experienced in last month	1.2	2.0	4.1	0.8	1.0	-0.6	1.1	1.7	2.0	1.6	1.7
Supplements: Calcium	0.7	0.8	2.4	1.5	0.7	-0.3	1.0	0.6	0.9	0.8	0.6
Basal cell carcinoma (self-reported)	0.3	0.3	0.8	0.9	0.5	-0.2	0.8	0.4	0.4	0.7	0.3
Heart attack/myocardial infarction (self-reported)	1.6	2.1	3.7	-1.8	1.2	-1.9	1.0	0.5	1.8	1.6	1.1
Deep venous thrombosis (DVT) (self-reported)	1.1	1.5	3.0	0.2	-1.6	1.7	-1.7	-0.5	0.6	-1.4	0.8
Heart disease (siblings)	0.1	0.2	0.5	-0.7	-0.2	-0.4	-0.3	-0.5	-0.2	-0.2	-0.2
Alcohol drinker status: Previous	1.1	1.2	2.6	0.6	-1.6	1.3	-1.5	0.1	0.2	-1.3	0.8
Pack years of smoking	1.6	2.3	6.2	-2.5	1.4	-2.3	0.9	0.5	1.2	1.2	0.9
Impedance of whole body	0.0	0.2	0.8	-0.1	0.3	-0.5	0.0	0.9	-0.2	-0.0	0.4
Leg fat mass (left)	0.2	0.6	1.7	-0.6	0.5	-0.6	0.6	-1.3	-0.5	0.7	-0.9
Arm predicted mass (left)	0.5	2.5	5.4	-1.9	0.9	-0.3	1.2	-2.3	-1.7	0.2	-2.3