[Hub]/) : Traits : Blood White Count : ← →

chr16:27,412,414-31,833,122

Best TWAS P=3.54e-63 · Best GWAS P=3.3e-63 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
77	YFS	Blood	ITGAL	0.02	0.02	lasso	2	0.02	2.9e-06	-15.95	-16.8	3.5e-63	0.90	0.02	0.97	TRUE
9	GTEx	Adrenal Gland	RP11-347C12.2	0.31	-0.01	lasso	9	0.03	3.7e-02	6.65	-11.5	1.4e-30	0.50	0.03	0.27	TRUE
83	YFS	Blood	ZNF785	0.05	0.07	lasso	4	0.06	2.0e-20	-8.74	-8.5	2.6e-17	0.18	1.00	0.00	TRUE
71	ROSMAP	Brain Pre-frontal Cortex	SETD1A	0.02	0.01	blup	232	0.02	4.3e-04	-6.12	-7.5	7.3e-14	0.24	0.32	0.20	TRUE
52	GTEx	Skin Sun Exposed Lower leg	RP11-347C12.2	0.13	0.00	enet	18	0.00	2.8e-01	9.62	7.3	2.1e-13	-0.35	0.03	0.27	TRUE
10	GTEx	Adrenal Gland	RP11-347C12.1	0.20	0.00	lasso	4	0.01	1.3e-01	-6.78	-7.2	4.9e-13	0.50	0.03	0.16	TRUE
30	GTEx	Esophagus Mucosa	BCKDK	0.05	0.05	enet	6	0.06	8.7e-05	4.54	6.4	1.8e-10	-0.19	0.23	0.50	TRUE
98	The Cancer Genome Atlas	Brain Lower Grade Glioma	XPO6	0.04	0.03	blup	58	0.03	2.1e-04	-6.46	-6.3	2.2e-10	-0.05	0.04	0.94	TRUE
62	GTEx	Thyroid	TBX6	0.24	0.00	enet	60	0.08	8.8e-07	2.34	-5.5	3.6e-08	0.16	0.14	0.03	TRUE
76	ROSMAP	Brain Pre-frontal Cortex	NPIPB6	0.14	0.12	bslmm	259	0.11	1.2e-13	-5.77	5.1	3.0e-07	0.03	0.74	0.26	TRUE
80	YFS	Blood	SEPHS2	0.08	0.05	enet	24	0.07	9.6e-22	-15.95	11.4	4.0e-30	-0.62	0.03	0.97	FALSE
70	NTR	Blood	ZNF48	0.01	0.00	blup	196	0.00	2.2e-02	-4.58	10.3	8.2e-25	-0.53	0.02	0.36	FALSE
47	GTEx	Pituitary	C16orf93	0.10	0.00	enet	14	0.00	2.4e-01	-6.36	9.6	5.4e-22	-0.31	0.05	0.10	FALSE
45	GTEx	Pituitary	YPEL3	0.12	0.04	lasso	4	0.05	2.5e-02	-3.83	-9.0	2.4e-19	0.46	0.11	0.19	FALSE
73	ROSMAP	Brain Pre-frontal Cortex	RP11-347C12.2	0.17	0.15	bslmm	207	0.14	2.2e-17	-7.63	-8.5	2.0e-17	0.60	1.00	0.00	FALSE
8	GTEx	Adrenal Gland	INO80E	0.35	0.00	lasso	4	0.05	5.4e-03	2.72	8.3	8.6e-17	-0.44	0.08	0.22	FALSE
11	GTEx	Artery Aorta	RNF40	0.12	0.02	lasso	4	0.03	1.2e-02	-6.38	-8.2	3.7e-16	0.30	0.09	0.05	FALSE
57	GTEx	Testis	C16orf93	0.10	0.09	lasso	3	0.08	1.4e-04	-6.32	8.2	3.7e-16	-0.17	0.49	0.04	FALSE
22	GTEx	Breast Mammary Tissue	RP11-347C12.1	0.10	0.05	enet	13	0.07	2.7e-04	-5.65	-7.8	5.4e-15	0.53	0.37	0.03	FALSE
20	GTEx	Brain Frontal Cortex BA9	C16orf93	0.25	0.13	enet	16	0.23	8.3e-07	3.99	7.8	6.5e-15	-0.24	0.18	0.09	FALSE
67	GTEx	Uterus	RP11-2C24.6	0.49	0.11	enet	22	0.24	1.2e-05	8.78	7.7	1.8e-14	-0.24	0.02	0.37	FALSE
21	GTEx	Brain Nucleus accumbens basal ganglia	C16orf93	0.30	0.00	lasso	9	0.01	1.8e-01	3.41	7.5	6.1e-14	-0.26	0.04	0.08	FALSE
74	ROSMAP	Brain Pre-frontal Cortex	C16orf93	0.19	0.26	lasso	10	0.28	5.1e-36	-6.38	7.5	6.9e-14	-0.15	1.00	0.00	FALSE
56	GTEx	Stomach	RP11-347C12.1	0.10	0.07	enet	14	0.05	1.4e-03	-7.63	-7.5	8.4e-14	0.48	0.24	0.34	FALSE
85	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC613037	0.07	0.04	enet	2	0.05	2.8e-10	-5.87	-7.3	2.8e-13	0.48	0.00	1.00	FALSE
110	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PRR14	0.08	0.05	blup	10	0.02	5.6e-02	-7.47	7.2	7.9e-13	-0.17	0.00	0.73	FALSE
75	ROSMAP	Brain Pre-frontal Cortex	RP11-347C12.1	0.18	0.12	lasso	9	0.16	1.8e-20	-6.76	-7.1	1.0e-12	0.57	1.00	0.00	FALSE
93	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C16orf93	0.14	0.11	blup	10	0.11	4.5e-07	-6.33	7.1	1.0e-12	-0.10	0.01	0.99	FALSE
35	GTEx	Lung	TBX6	0.27	0.05	enet	20	0.16	6.3e-12	-3.53	-7.1	1.2e-12	0.37	0.88	0.02	FALSE
43	GTEx	Ovary	STX4	0.16	0.05	enet	13	0.07	9.0e-03	-4.68	-7.1	1.2e-12	0.15	0.02	0.78	FALSE
39	GTEx	Muscle Skeletal	RP11-347C12.1	0.04	0.02	enet	7	0.04	1.8e-04	2.94	-7.1	1.5e-12	0.52	0.43	0.32	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LOC595101	0.28	0.33	enet	18	0.36	9.8e-46	-6.78	-7.0	2.6e-12	0.54	1.00	0.00	FALSE
13	GTEx	Artery Aorta	RP11-347C12.2	0.05	0.01	enet	3	0.00	3.1e-01	-6.76	-7.0	3.2e-12	0.48	0.10	0.12	FALSE
50	GTEx	Skin Not Sun Exposed Suprapubic	RP11-347C12.1	0.29	0.21	enet	13	0.27	4.1e-15	-7.63	-6.9	4.2e-12	0.51	1.00	0.00	FALSE
72	ROSMAP	Brain Pre-frontal Cortex	ZNF689	0.06	0.06	lasso	3	0.06	1.8e-08	-7.11	6.9	4.3e-12	-0.19	1.00	0.00	FALSE
29	GTEx	Esophagus Gastroesophageal Junction	INO80E	0.15	0.00	lasso	6	0.02	4.3e-02	-2.14	6.9	4.8e-12	-0.35	0.17	0.19	FALSE
24	GTEx	Breast Mammary Tissue (Female)	RP11-347C12.1	0.16	0.16	lasso	2	0.09	1.1e-03	-6.78	-6.7	1.7e-11	0.48	0.14	0.06	FALSE
49	GTEx	Prostate	RP11-347C12.1	0.18	0.11	lasso	5	0.06	1.4e-02	-6.78	-6.6	4.7e-11	0.48	0.08	0.17	FALSE
3	CommonMind	Brain Pre-frontal Cortex	VKORC1	0.03	0.04	lasso	3	0.03	4.9e-05	6.65	6.5	6.0e-11	-0.26	0.32	0.03	FALSE
89	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LOC595101	0.11	0.02	enet	8	0.05	9.1e-07	2.94	6.5	6.3e-11	-0.54	0.11	0.57	FALSE
82	YFS	Blood	ZNF689	0.06	0.04	lasso	5	0.06	1.7e-18	-7.47	6.5	7.0e-11	-0.26	1.00	0.00	FALSE
111	The Cancer Genome Atlas	Thyroid Carcinoma	C16orf93	0.15	0.19	lasso	4	0.19	1.8e-18	-6.33	6.5	7.0e-11	-0.08	0.01	0.99	FALSE
90	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C16orf93	0.02	0.02	blup	11	0.02	1.5e-03	-6.33	6.5	9.1e-11	-0.05	0.01	0.57	FALSE
64	GTEx	Thyroid	C16orf93	0.17	0.18	lasso	4	0.18	1.6e-13	-6.29	6.5	1.0e-10	-0.06	1.00	0.00	FALSE
101	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC595101	0.05	0.00	enet	5	0.02	1.1e-03	-3.57	6.4	1.2e-10	-0.54	0.05	0.14	FALSE
105	The Cancer Genome Atlas	Prostate Adenocarcinoma	MAPK3	0.07	0.09	lasso	4	0.11	9.0e-12	5.21	6.4	1.3e-10	-0.46	0.01	0.99	FALSE
26	GTEx	Cells Transformed fibroblasts	RP11-347C12.1	0.14	0.13	lasso	5	0.15	1.7e-11	-7.63	-6.4	1.7e-10	0.47	1.00	0.00	FALSE
44	GTEx	Ovary	RP11-347C12.1	0.22	0.10	lasso	5	0.13	4.8e-04	-7.43	-6.4	1.7e-10	0.45	0.16	0.13	FALSE
103	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RNF40	0.10	0.07	lasso	3	0.06	1.1e-03	-6.38	-6.4	1.9e-10	0.07	0.01	0.68	FALSE
61	GTEx	Thyroid	RNF40	0.07	0.03	lasso	3	0.03	1.5e-03	-6.06	-6.3	2.1e-10	0.04	0.45	0.02	FALSE
17	GTEx	Artery Tibial	RP11-347C12.1	0.15	0.09	lasso	7	0.12	7.9e-10	-6.76	-6.3	2.2e-10	0.51	1.00	0.00	FALSE
106	The Cancer Genome Atlas	Prostate Adenocarcinoma	RNF40	0.07	0.11	lasso	5	0.10	7.5e-11	-6.33	-6.3	2.2e-10	0.07	0.01	0.99	FALSE
32	GTEx	Esophagus Muscularis	RNF40	0.16	0.10	lasso	1	0.08	1.3e-05	-6.32	-6.3	2.7e-10	0.08	0.56	0.02	FALSE
69	METSIM	Adipose	RP11-347C12.1	0.06	0.02	bslmm	209	0.04	4.3e-07	-0.43	-6.3	2.7e-10	0.57	0.42	0.53	FALSE
112	The Cancer Genome Atlas	Thyroid Carcinoma	LOC595101	0.26	0.13	enet	11	0.21	8.2e-20	-3.19	6.3	2.8e-10	-0.53	0.76	0.06	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SETD1A	0.04	0.03	bslmm	243	0.02	3.9e-03	-5.75	-6.3	3.0e-10	0.04	0.22	0.03	FALSE
79	YFS	Blood	PRR14	0.02	0.01	blup	184	0.01	2.0e-05	-6.38	6.3	3.9e-10	-0.16	0.74	0.00	FALSE
65	GTEx	Uterus	FBRS	0.21	0.07	lasso	10	0.07	1.7e-02	4.61	6.2	4.1e-10	-0.32	0.04	0.49	FALSE
51	GTEx	Skin Sun Exposed Lower leg	XPO6	0.11	0.08	lasso	5	0.07	1.2e-06	-6.08	-6.2	4.3e-10	-0.04	0.03	0.97	FALSE
95	The Cancer Genome Atlas	Brain Lower Grade Glioma	C16orf93	0.09	0.09	blup	11	0.09	1.0e-10	-6.06	6.2	4.4e-10	-0.06	0.02	0.98	FALSE
6	GTEx	Adipose Subcutaneous	TBX6	0.11	0.04	enet	20	0.06	2.0e-05	5.21	-6.2	5.3e-10	0.40	0.88	0.03	FALSE
63	GTEx	Thyroid	XPO6	0.07	0.06	enet	8	0.06	3.7e-05	-6.06	-6.2	7.6e-10	-0.07	0.04	0.95	FALSE
104	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC595101	0.19	0.04	enet	8	0.14	1.2e-14	-3.10	6.1	8.3e-10	-0.54	0.77	0.04	FALSE
41	GTEx	Nerve Tibial	RNF40	0.13	0.08	lasso	5	0.09	8.1e-07	-6.38	-6.1	8.4e-10	0.03	0.98	0.00	FALSE
14	GTEx	Artery Aorta	RP11-347C12.1	0.09	0.07	lasso	4	0.08	2.2e-05	-7.43	-6.1	8.7e-10	0.48	0.64	0.10	FALSE
28	GTEx	Colon Transverse	RP11-347C12.1	0.15	0.06	enet	11	0.11	9.4e-06	2.94	-6.1	9.8e-10	0.42	0.39	0.12	FALSE
34	GTEx	Heart Left Ventricle	RP11-347C12.1	0.06	0.03	lasso	8	0.01	8.0e-02	5.21	-6.1	1.1e-09	0.46	0.17	0.21	FALSE
66	GTEx	Uterus	C16orf93	0.23	0.00	lasso	5	0.06	2.5e-02	-6.38	6.1	1.1e-09	-0.23	0.05	0.06	FALSE
81	YFS	Blood	XPO6	0.03	0.03	lasso	3	0.03	9.8e-11	-6.61	-6.1	1.3e-09	-0.05	0.02	0.98	FALSE
23	GTEx	Breast Mammary Tissue (Male)	CCDC101	0.10	-0.01	enet	10	-0.01	5.1e-01	-2.32	6.1	1.4e-09	0.00	0.02	0.20	FALSE
48	GTEx	Prostate	YPEL3	0.23	0.06	enet	15	0.05	2.1e-02	-3.53	-6.0	1.6e-09	0.31	0.13	0.13	FALSE
5	GTEx	Adipose Subcutaneous	RNF40	0.18	0.10	lasso	7	0.11	3.7e-09	-6.38	-6.0	1.7e-09	0.03	1.00	0.00	FALSE
99	The Cancer Genome Atlas	Lung Adenocarcinoma	LOC595101	0.08	0.05	enet	8	0.06	2.0e-07	-3.32	6.0	1.8e-09	-0.52	0.74	0.05	FALSE
91	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC595101	0.13	0.00	enet	7	0.03	7.7e-05	-5.52	6.0	2.5e-09	-0.53	0.00	0.79	FALSE
25	GTEx	Cells Transformed fibroblasts	RNF40	0.08	0.04	lasso	8	0.04	5.6e-04	-6.29	-6.0	2.6e-09	0.04	0.55	0.02	FALSE
68	METSIM	Adipose	RNF40	0.12	0.07	lasso	4	0.07	1.1e-10	-6.06	-5.9	3.1e-09	0.00	1.00	0.00	FALSE
114	The Cancer Genome Atlas	Thyroid Carcinoma	XPO6	0.03	0.01	blup	58	0.02	1.2e-02	-5.89	-5.9	3.2e-09	-0.06	0.02	0.57	FALSE
53	GTEx	Small Intestine Terminal Ileum	VKORC1	0.30	0.05	enet	18	0.12	1.4e-03	4.82	-5.9	3.4e-09	0.13	0.06	0.12	FALSE
37	GTEx	Lung	RP11-347C12.1	0.05	0.04	enet	6	0.05	5.2e-05	5.21	-5.9	4.0e-09	0.47	0.78	0.06	FALSE
102	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC613037	0.03	0.02	lasso	1	0.02	1.2e-03	-5.87	-5.9	4.2e-09	0.44	0.00	0.86	FALSE
88	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HSD3B7	0.06	0.01	blup	31	0.02	7.4e-04	-4.34	-5.8	5.0e-09	0.09	0.17	0.17	FALSE
58	GTEx	Testis	RP11-347C12.1	0.13	0.13	enet	11	0.13	1.5e-06	2.94	-5.8	5.9e-09	0.51	0.48	0.17	FALSE
31	GTEx	Esophagus Mucosa	RP11-347C12.1	0.15	0.02	enet	15	0.07	1.1e-05	-6.78	-5.8	6.2e-09	0.41	0.72	0.02	FALSE
92	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TBX6	0.13	0.04	enet	10	0.09	1.9e-10	-3.90	-5.8	8.3e-09	0.28	0.13	0.69	FALSE
7	GTEx	Adipose Subcutaneous	RP11-347C12.1	0.14	0.08	lasso	11	0.15	4.5e-12	-6.76	-5.8	8.4e-09	0.48	1.00	0.00	FALSE
94	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	MAPK3	0.04	0.02	blup	19	0.04	2.0e-03	3.63	5.7	1.0e-08	-0.43	0.01	0.63	FALSE
100	The Cancer Genome Atlas	Lung Adenocarcinoma	TBX6	0.03	0.01	blup	18	0.01	1.1e-02	-3.90	-5.7	1.2e-08	0.31	0.01	0.36	FALSE
16	GTEx	Artery Tibial	TBX6	0.21	0.13	lasso	4	0.18	3.5e-14	-3.53	-5.7	1.5e-08	0.28	1.00	0.00	FALSE
59	GTEx	Thyroid	HSD3B7	0.27	0.12	lasso	4	0.17	7.0e-13	-3.03	-5.7	1.6e-08	0.14	1.00	0.00	FALSE
60	GTEx	Thyroid	GDPD3	0.25	0.01	enet	26	0.10	6.4e-08	-8.28	-5.6	1.8e-08	0.14	0.20	0.03	FALSE
4	GTEx	Adipose Subcutaneous	STX4	0.06	0.05	lasso	2	0.02	7.8e-03	-5.76	-5.6	1.9e-08	0.05	0.10	0.59	FALSE
33	GTEx	Heart Left Ventricle	TBX6	0.16	0.14	enet	10	0.12	7.8e-07	3.65	-5.6	2.7e-08	0.35	0.84	0.02	FALSE
55	GTEx	Stomach	RP11-347C12.2	0.13	0.03	enet	15	0.07	4.5e-04	0.82	-5.6	2.7e-08	0.32	0.11	0.06	FALSE
54	GTEx	Spleen	INO80E	0.23	0.20	enet	13	0.26	2.6e-07	2.41	5.5	2.8e-08	-0.29	0.82	0.02	FALSE
40	GTEx	Nerve Tibial	MAPK3	0.15	0.02	enet	12	0.09	1.2e-06	3.63	5.5	4.9e-08	-0.45	0.64	0.08	FALSE
27	GTEx	Colon Transverse	GDPD3	0.18	0.05	enet	21	0.07	2.1e-04	-8.28	-5.5	5.0e-08	0.19	0.09	0.12	FALSE
42	GTEx	Nerve Tibial	RP11-347C12.1	0.22	0.08	enet	9	0.13	1.0e-09	-6.78	-5.5	5.0e-08	0.46	1.00	0.00	FALSE
15	GTEx	Artery Coronary	TBX6	0.22	0.00	enet	17	0.02	6.7e-02	2.08	-5.4	5.8e-08	0.33	0.08	0.22	FALSE
46	GTEx	Pituitary	RP11-347C12.2	0.18	0.01	enet	9	0.02	1.2e-01	5.21	-5.4	6.5e-08	0.47	0.11	0.05	FALSE
108	The Cancer Genome Atlas	Soft Tissue Sarcoma	TBX6	0.06	0.01	blup	18	0.02	1.3e-02	-3.53	-5.4	7.3e-08	0.32	0.00	0.21	FALSE
113	The Cancer Genome Atlas	Thyroid Carcinoma	TBX6	0.15	0.06	enet	6	0.15	8.9e-15	-3.53	-5.4	8.3e-08	0.32	0.00	0.99	FALSE
12	GTEx	Artery Aorta	TBX6	0.14	0.02	lasso	7	0.03	1.2e-02	-3.85	-5.3	8.7e-08	0.24	0.41	0.02	FALSE
97	The Cancer Genome Atlas	Brain Lower Grade Glioma	TBX6	0.09	0.07	enet	8	0.08	1.8e-09	-3.53	-5.3	8.7e-08	0.28	0.20	0.56	FALSE
78	YFS	Blood	MVP	0.05	0.02	bslmm	150	0.03	4.3e-10	-3.85	-5.3	1.0e-07	0.18	0.95	0.01	FALSE
96	The Cancer Genome Atlas	Brain Lower Grade Glioma	LOC595101	0.09	0.05	enet	11	0.07	9.5e-09	-3.89	5.3	1.3e-07	-0.52	0.70	0.12	FALSE
87	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC595101	0.09	0.04	enet	9	0.07	5.5e-05	-3.89	5.3	1.4e-07	-0.40	0.12	0.05	FALSE
107	The Cancer Genome Atlas	Prostate Adenocarcinoma	TBX6	0.18	0.09	enet	7	0.15	8.5e-16	-3.53	-5.2	1.5e-07	0.30	0.29	0.35	FALSE
19	GTEx	Brain Cortex	KAT8	0.14	0.14	lasso	3	0.10	8.9e-04	5.40	-5.2	1.6e-07	0.16	0.15	0.24	FALSE
18	GTEx	Brain Cerebellum	RNF40	0.24	0.16	lasso	5	0.13	9.7e-05	-6.06	-5.2	1.8e-07	-0.01	0.26	0.04	FALSE
109	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MAPK3	0.13	0.11	lasso	1	0.08	7.2e-04	5.21	5.2	1.9e-07	-0.41	0.02	0.64	FALSE
84	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC595101	0.08	0.05	enet	7	0.06	9.6e-13	-3.32	5.2	2.0e-07	-0.52	0.77	0.04	FALSE
36	GTEx	Lung	RP11-347C12.2	0.04	0.03	enet	11	0.04	8.8e-04	5.21	-5.2	2.3e-07	0.40	0.40	0.05	FALSE
86	The Cancer Genome Atlas	Breast Invasive Carcinoma	TBX6	0.04	0.01	blup	18	0.04	5.9e-08	3.63	-5.2	2.5e-07	0.33	0.01	0.97	FALSE
38	GTEx	Muscle Skeletal	SULT1A1	0.10	0.04	enet	20	0.05	7.5e-06	0.62	-5.2	2.7e-07	-0.08	0.85	0.09	FALSE