TWAS hub - PRR14

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0174	0.0074	0.00014	0.007	0.014	0.008	0.013	0.008	0.0019	0.00002	0.00063	3.3e-05	0.00079
2	TCGA	Testicular Germ Cell Tumors	0.0820	0.0580	0.00840	0.047	0.022	0.003	NA	0.014	0.0091	0.05500	0.25000	NA	0.10000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Bendroflumethiazide	13.3	20.2	20.3	-4.5	-4.5
Comparative body size at age 10	10.8	30.0	36.0	-6.0	-4.9
Waist circumference	10.5	38.3	40.1	-6.3	-6.0
Hip circumference	10.1	43.6	46.9	-6.8	-6.3
Arm fat mass (left)	10.1	41.5	48.4	-7.0	-5.9
Body mass index (BMI)	9.5	40.3	47.2	-6.9	-5.8
Weight	9.5	46.5	52.7	-7.3	-6.3
Arm fat mass (right)	9.5	39.3	44.5	-6.7	-5.8
Alcohol intake frequency.	8.7	20.2	22.2	-4.3	-4.7
Arm fat percentage (left)	8.7	34.6	39.8	-6.3	-5.4
Leg fat mass (left)	8.6	33.5	35.0	-5.9	-5.7
Blood Red Count	8.5	81.8	136.9	11.7	5.2
Alzheimer’s Disease (including proxy)	8.3	12.0	13.4	3.3	3.7
Primary Biliary Cirrhosis	8.3	11.8	17.6	-4.2	-2.5
Arm fat percentage (right)	7.9	31.2	34.9	-5.9	-5.2
Leg fat mass (right)	7.9	30.5	31.8	-5.6	-5.4
Whole body fat mass	7.8	32.4	35.3	-5.9	-5.4
Leg fat-free mass (right)	7.8	41.6	54.3	-7.4	-5.4
Rheumatoid Arthritis	7.7	10.5	12.3	-3.0	-3.5
Leg predicted mass (right)	7.7	41.0	53.6	-7.3	-5.3
Blood Eosinophil Count	7.3	56.5	63.5	8.0	7.0
Diastolic blood pressure, automated reading	7.3	22.5	26.4	-4.3	-5.1
Leg fat-free mass (left)	7.2	38.1	48.4	-7.0	-5.3
Leg predicted mass (left)	7.0	37.0	47.2	-6.9	-5.2
Trunk fat mass	7.0	30.0	32.8	-5.7	-5.2
Number of incorrect matches in round	6.8	11.4	17.6	4.2	2.2
Impedance of leg (right)	6.6	32.1	47.5	6.9	4.1
Asthma (self-reported)	6.6	13.1	20.1	-4.5	-2.5
Alzheimer’s Disease (in mother)	6.5	7.7	8.3	2.9	2.6
Lung FEV1/FVC ratio	6.5	32.8	36.7	6.1	5.4
Triglycerides	6.4	10.6	11.5	-3.4	-3.1
Medication: Atorvastatin	6.4	7.9	12.2	-1.9	-3.5
Respiratory disease	6.3	14.1	20.1	-4.5	-2.8
Basal metabolic rate	6.3	34.8	42.0	-6.5	-5.2
Blood White Count	6.1	45.2	51.3	6.3	7.2
BMI	6.1	35.3	43.7	-6.6	-5.2
Asthma	6.1	12.1	18.6	-4.3	-2.4
Suffer from ‘nerves’	6.1	9.5	10.1	3.0	3.2
Body fat percentage	6.0	23.6	24.0	-4.9	-4.8
High blood pressure	5.9	16.5	18.0	-3.9	-4.2
Pulse rate, automated reading	5.8	18.6	20.6	-4.1	-4.5
Wheeze or whistling in the chest in last year	5.7	10.3	17.5	-4.2	-1.7
Leg fat percentage (left)	5.7	20.5	21.7	-4.4	-4.7
Trunk fat percentage	5.6	22.4	23.3	-4.8	-4.6
Pain all over the body in last month	5.5	5.9	8.2	-1.9	-2.9
Arm predicted mass (right)	5.4	27.7	32.1	-5.7	-4.8
Vascular/heart problems diagnosed by doctor	5.3	14.5	16.5	3.5	4.1
Arm fat-free mass (right)	5.2	26.7	31.1	-5.6	-4.7
Medication: Ventolin 100micrograms inhaler	5.1	6.6	11.6	-3.4	-1.2
Hypertension (Self-reported)	5.1	14.0	14.7	-3.6	-3.8
Whole body fat-free mass	5.1	28.9	35.4	-6.0	-4.7
Impedance of leg (left)	5.0	24.5	37.5	6.1	3.4
Frequency of tenseness / restlessness in last 2 weeks	5.0	7.7	8.7	3.0	2.6
Whole body water mass	5.0	28.6	35.2	-5.9	-4.7
Medication: Blood pressure	4.9	9.3	10.9	-3.3	-2.8
Arm predicted mass (left)	4.8	24.2	26.5	-5.2	-4.7
Arm fat-free mass (left)	4.7	23.9	27.5	-5.2	-4.5
Heel T-Score	4.4	34.6	34.7	5.9	5.9
Tinnitus: Yes, but not now, but have in the past	4.4	4.7	5.1	-2.0	-2.3
Pulse wave Arterial Stiffness index	4.2	5.0	5.7	-2.4	-2.0
Leg fat percentage (right)	4.0	14.6	16.5	-3.6	-4.1
Illnesses of father: Heart disease	4.0	5.5	7.7	2.8	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.0	8.5	10.5	2.5	3.2
Hand grip strength (left)	3.8	10.0	12.1	-3.5	-2.8
Hand grip strength (right)	3.8	10.3	11.0	-3.3	-3.1
Nervous feelings	3.8	7.1	10.6	1.9	3.3
Breast cancer (self-reported)	3.8	4.5	5.2	-2.3	-1.9
Supplements: Fish oil (including cod liver oil)	3.8	5.0	6.2	2.5	1.9
Cardiovascular Disease	3.7	12.3	12.7	-3.4	-3.6
Illnesses of father: None of the above (group 1)	3.7	4.5	7.4	-2.7	-1.3
Medication: Co-codamol	3.6	4.1	5.0	-1.8	-2.2
Birth weight of first child	3.5	6.4	9.9	-3.1	-1.7
Emphysema/chronic bronchitis	3.5	3.9	6.8	-2.6	-1.0
Impedance of whole body	3.5	17.8	24.7	5.0	3.3
Pulse wave peak to peak time	3.4	4.0	4.5	2.1	1.9
Average weekly champagne plus white wine intake	3.4	4.7	5.3	2.0	2.3
Medication: Aspirin	3.3	4.4	6.5	2.5	1.5
Number of treatments/medications taken	3.2	5.8	6.2	-2.5	-2.3
Trunk fat-free mass	3.2	18.6	21.9	-4.7	-3.9
Trunk predicted mass	3.2	18.3	21.7	-4.7	-3.9
Age at last live birth	3.2	4.6	5.2	2.3	2.0
Pain experienced in last month	3.2	5.3	7.0	2.6	1.9
Medication: Aspirin	3.1	4.0	6.1	2.5	1.4
Irritability	3.1	5.3	8.9	1.3	3.0
Blood Platelet Count	3.0	35.1	36.7	5.8	6.1
Tense / ‘highly strung’	3.0	5.0	7.2	1.6	2.7
Ever smoked	3.0	5.3	7.3	1.8	2.7
Financial difficulties in last 2 years	2.9	3.9	5.9	-1.4	-2.4
Smoking status: Previous	2.8	4.2	5.1	1.9	2.2
Past tobacco smoking	2.7	5.0	7.0	-1.8	-2.6
Medication: Lisinopril	2.7	3.5	4.9	-2.2	-1.5
Alzheimer’s Disease (in father)	2.6	2.8	3.4	1.5	1.9
Medication for cholesterol	2.6	3.9	5.1	1.6	2.3
Number of self-reported non-cancer illnesses	2.6	4.5	7.1	-1.4	-2.7
Crohns Disease (2017)	2.5	5.5	7.0	2.6	2.0
Crohns Disease (2012)	2.5	3.9	4.2	1.9	2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	3.0	5.7	-2.4	-0.5
Age started oral contraceptive pill	2.4	3.0	3.8	-2.0	-1.4
Unable to work because of sickness or disability	2.4	3.1	4.4	-1.3	-2.1
High cholesterol (Self-reported)	2.3	4.0	7.4	-0.8	-2.7
Breastfed as a baby	2.2	2.7	2.8	-1.6	-1.7
Pulse wave reflection index	2.2	2.7	4.9	-2.2	-0.8
Average weekly beer plus cider intake	2.2	3.3	3.6	1.9	1.7
Sitting height	2.1	14.7	18.9	4.3	3.2
Impedance of arm (right)	2.1	9.8	12.4	3.5	2.7
Lung cancer (father)	2.1	2.4	3.8	-2.0	-1.0
Neck or shoulder pain in last month	2.1	3.0	4.7	-2.2	-1.2
Fasting Glucose	2.0	2.4	3.1	1.3	1.8
Knee pain experienced in last month	2.0	3.1	6.2	-2.5	0.0
Prostate Cancer	1.9	2.7	4.4	-1.0	-2.1
Overall health rating	1.9	4.1	5.5	-1.7	-2.3
Cholesterol lowering medication	1.9	2.7	4.1	-1.2	-2.0
Illnesses of siblings	1.8	2.6	3.2	1.4	1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	3.3	1.8	0.9
Mouth/teeth dental problems: Mouth ulcers	1.8	2.8	4.9	0.9	2.2
Back pain experienced in last month	1.8	2.7	4.8	-2.2	-0.7
HbA1C	1.7	1.8	3.3	-0.6	-1.8
Average weekly fortified wine intake	1.7	1.9	3.3	0.7	1.8
Taking other prescription medications	1.7	2.6	4.5	-2.1	-0.9
High blood pressure (siblings)	1.7	2.4	3.0	-1.4	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	3.7	1.9	0.8
Qualifications: College or University degree	1.7	5.4	6.1	2.2	2.5
Medication: Blood pressure	1.7	3.0	4.5	-1.2	-2.1
Supplements: Calcium	1.7	1.9	2.9	-0.9	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.7	4.3	1.8	2.1
Qualifications: CSEs or equivalent	1.6	2.1	2.3	-1.4	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.8	4.5	1.7	2.1
Eye problems/disorders: None of the above	1.6	1.8	3.1	-1.8	-0.7
Impedance of arm (left)	1.5	6.9	8.2	2.9	2.4
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	1.8	1.4	1.2
Basal cell carcinoma (self-reported)	1.5	1.8	3.4	1.9	0.3
Heart attack	1.4	1.7	1.8	1.3	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.6	6.6	1.6	2.6
Length of working week for main job	1.4	1.5	2.1	-1.0	-1.5
Mineral and other dietary supplements	1.4	1.9	2.6	-1.6	-1.1
Wears glasses or contact lenses	1.4	1.6	2.4	-1.6	-0.9
Smoking Status	1.3	3.1	4.7	1.2	2.2
Commuting to job workplace: Car/motor vehicle	1.3	1.5	1.5	1.2	1.2
Number of operations (self-reported)	1.3	1.9	2.8	-1.0	-1.7
Worry (Nagel 2018)	1.2	2.6	4.3	0.9	2.1
Lupus	1.2	1.8	3.5	-1.9	-0.3
Had other major operations	1.2	1.4	1.7	-1.3	-1.1
Medication: Ramipril	1.2	1.5	2.7	-0.5	-1.6
Falls in the last year	1.2	1.6	3.2	0.0	-1.8
Health satisfaction	1.2	1.5	2.9	0.5	-1.7
Supplements: Glucosamine	1.1	1.4	1.6	1.3	1.1
Pulse rate	1.1	1.9	2.3	-1.2	-1.5
Medication: Lansoprazole	1.1	1.3	1.6	-1.3	-1.0
Eye problems/disorders: Cataract	1.1	1.2	2.5	1.6	-0.0
Height	1.0	19.9	20.0	-4.5	-4.5
Type 2 Diabetes (T2D) (2018)	1.0	1.8	2.0	-1.3	-1.4
Medication for hormone replacement therapy	1.0	1.1	2.2	1.5	0.3
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	1.7	-0.9	1.3
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.2	-1.5	-0.4
Heart attack/myocardial infarction (self-reported)	1.0	1.3	1.6	1.2	1.0
Townsend deprivation index at recruitment	0.9	1.2	1.6	-0.9	-1.3
Maternal smoking around birth	0.9	1.4	2.7	0.2	1.6
Stomach or abdominal pain in last month	0.9	1.1	2.2	1.5	0.3
Worrier / anxious feelings	0.9	1.6	3.1	0.4	1.8
Depression (self-reported)	0.9	1.1	1.4	-0.9	-1.2
Headache pain in last month	0.9	1.5	2.3	-1.5	-0.9
Long-standing illness, disability or infirmity	0.9	1.4	1.7	-1.3	-1.0
Miserableness	0.9	1.5	2.6	0.7	1.6
Ever used hormone-replacement therapy (HRT)	0.8	1.0	1.8	1.3	0.5
Diabetes (mother)	0.8	1.0	1.7	-0.6	-1.3
Fed-up feelings	0.8	1.5	2.8	-1.7	-0.3
Age when periods started (menarche)	0.8	1.9	2.2	-1.5	-1.3
Allergy	0.8	1.8	3.4	1.8	0.4
Alcohol intake versus 10 years previously	0.8	1.2	1.7	-1.3	-0.9
Father’s age at death	0.8	1.0	1.9	0.4	1.4
Hair/balding pattern: Pattern 4	0.8	2.0	2.4	-1.2	-1.6
Medication: Paracetamol	0.8	1.4	2.8	-1.7	-0.1
Number of children fathered	0.8	0.9	1.7	-0.3	1.3
Age at first live birth	0.8	1.4	1.5	1.2	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	1.5	0.7	1.2
Supplements: Vitamin C	0.8	1.0	1.5	1.2	0.7
Guilty feelings	0.8	1.2	2.1	-0.6	-1.4
Irritable Bowel Disease (IBD)	0.7	1.7	2.0	1.1	1.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.7	-0.3	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.6	1.3	0.5
Qualifications: None of the above	0.7	1.4	2.7	-1.6	-0.4
Happiness	0.7	0.9	1.0	1.0	0.9
Medication: Amlodipine	0.7	1.0	1.1	1.0	1.0
Medication: Gliclazide	0.7	0.8	1.1	-1.0	-0.7
Bipolar Disorder or Schizophrenia	0.6	1.6	2.0	-1.1	-1.4
Age at First Birth	0.6	0.9	1.3	0.7	1.1
Coronary Artery Disease (CAD)	0.6	0.8	1.5	0.0	1.2
Neuroticism (2016)	0.6	0.8	1.2	0.6	1.1
Lung FVC	0.6	3.2	5.6	0.9	2.4
Ever had hysterectomy (womb removed)	0.6	0.6	0.7	0.8	-0.8
Exposure to tobacco smoke outside home	0.6	0.7	1.4	-0.3	-1.2
Osteoporosis (self-reported)	0.6	0.8	1.0	-0.7	-1.0
Illnesses of father: High blood pressure	0.6	0.7	1.0	1.0	0.7
Schizophrenia (2018)	0.5	1.0	1.1	-0.9	-1.0
Neuroticism	0.5	1.1	2.2	-0.1	1.5
Qualifications: A levels/AS levels or equivalent	0.5	1.1	1.3	1.1	1.0
Mouth/teeth dental problems: Dentures	0.5	0.8	1.0	-0.7	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.1	-1.1	-0.3
Medication: Cholesterol lowering	0.5	0.8	1.6	-0.1	-1.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.7	0.2	1.3
Heart disease (mother)	0.5	0.6	0.7	0.7	0.9
Average weekly red wine intake	0.5	0.7	1.1	1.0	0.5
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.0	0.4	1.0
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.0	1.0	0.5
Bipolar Disorder (2018)	0.4	0.6	1.0	-0.6	-1.0
Neuroticism (Nagel 2018)	0.4	0.9	1.7	-0.0	1.3
Chronotype (morning person)	0.4	1.0	1.0	-1.0	-1.0
Vitamin and mineral supplements	0.4	0.5	1.0	0.2	1.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	0.9	0.9	0.4
Medication: Levothyroxine sodium	0.4	0.6	0.9	0.6	-0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	0.9	-0.9	0.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	2.5	0.5	1.6
Ever highly irritable/argumentative for 2 days	0.4	0.5	0.9	0.0	1.0
Loud music exposure frequency	0.4	0.5	0.9	0.2	0.9
Birth weight	0.4	0.8	1.2	-1.1	-0.7
Medication for pain relief, constipation, heartburn	0.4	0.7	1.4	1.2	-0.0
Chest pain or discomfort	0.4	0.6	1.2	-0.1	-1.1
Mood swings	0.4	0.7	0.7	-0.8	0.9
Friendships satisfaction	0.4	0.5	1.0	-0.3	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	0.8	0.4	-0.9
Fractured/broken bones in last 5 years	0.4	0.5	0.8	-0.9	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.7	-0.8	0.6
Depressed Affect (Nagel 2018)	0.3	0.7	1.3	-1.1	0.4
Body Mass Index (BMI) (2010)	0.3	0.4	0.8	-0.9	0.1
Schizophrenia (2014)	0.3	0.7	0.8	-0.8	-0.9
Ulcerative Colitis	0.3	0.5	0.9	-1.0	0.1
Hypothyroidism (self reported)	0.3	0.7	1.3	1.1	-0.3
Hearing difficulty/problems: Yes	0.3	0.4	0.7	0.3	-0.9
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.4	0.7	0.5
Supplements: Zinc	0.3	0.3	0.5	0.3	0.7
Severe depression (siblings)	0.3	0.3	0.4	-0.6	-0.5
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.4	-0.7	-0.5
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.1	-1.1	0.2
Multivitamins +/- minerals	0.3	0.4	0.7	0.9	-0.2
Alcohol usually taken with meals	0.3	0.5	1.0	-1.0	-0.1
Hearing difficulty/problems with background noise	0.3	0.4	0.7	0.8	-0.4
Hair/balding pattern: Pattern 2	0.3	0.3	0.5	0.3	0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	0.6	-0.2	-0.8
Diabetes (self-reported)	0.3	0.5	0.6	-0.6	-0.8
Neuroticism score	0.3	0.6	1.3	-0.0	1.1
Noisy workplace	0.3	0.4	0.5	0.6	0.7
Illnesses of mother	0.3	0.4	0.8	0.1	0.9
Standing height	0.3	2.7	3.4	-1.4	-1.8
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.6	-0.8	-0.2
Medication: Seretide 50 evohaler	0.3	0.4	0.7	-0.8	0.3
Had major operations	0.3	0.3	0.6	0.8	0.1
Illnesses of siblings: Diabetes	0.3	0.3	0.6	-0.1	-0.8
Diabetes diagnosed by doctor	0.3	0.4	0.5	-0.6	-0.7
Financial situation satisfaction	0.3	0.3	0.7	-0.0	-0.8
Myopia	0.3	0.5	0.8	-0.9	-0.3
Heart disease (siblings)	0.3	0.3	0.5	0.4	-0.7
Alcohol drinker status: Previous	0.3	0.3	0.5	-0.5	-0.7
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.0	0.3	1.0
Ulcerative Colitis (UC)	0.2	0.4	0.4	-0.6	0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.9	-0.1	1.0
Mean Putamen Volume	0.2	0.2	0.5	-0.7	-0.0
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.4	0.0	0.6
Systolic Blood Pressure	0.2	0.9	1.4	0.6	-1.2
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.7	-0.1	0.8
Relative age of first facial hair	0.2	0.4	0.7	-0.8	0.0
Systolic blood pressure, automated reading	0.2	0.5	0.9	0.2	-0.9
Medication: Metformin	0.2	0.2	0.4	-0.6	-0.3
Medication: Atenolol	0.2	0.3	0.5	0.7	0.2
High blood pressure (mother)	0.2	0.3	0.5	-0.7	-0.4
Had menopause	0.2	0.2	0.4	-0.2	-0.6
Time employed in main current job	0.2	0.2	0.4	-0.1	-0.6
Number of live births	0.2	0.3	0.4	0.7	0.4
Exposure to tobacco smoke at home	0.2	0.2	0.2	-0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.5	0.7	0.1
Blood clot in the leg (DVT)	0.2	0.3	0.4	0.6	0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	0.8	-0.3
Forced vital capacity (FVC), Best measure	0.2	0.8	1.6	-0.0	1.3
Worry too long after embarrassment	0.2	0.3	0.4	0.6	0.6
Shortness of breath walking on level ground	0.2	0.2	0.3	-0.2	0.6
Migraine (self-reported)	0.2	0.2	0.2	0.5	0.5
Medication: Ibuprofen	0.2	0.2	0.5	-0.7	0.1
Medication: Omeprazole	0.2	0.2	0.3	-0.5	0.5
Family relationship satisfaction	0.2	0.2	0.3	0.6	0.3
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.6	0.0	-0.7
Loneliness, isolation	0.2	0.3	0.4	0.6	0.5
Ever had bowel cancer screening	0.2	0.3	0.5	0.3	-0.7
Qualifications: nursing, teaching	0.2	0.3	0.4	0.6	0.5
Commuting to job workplace: Walk	0.2	0.2	0.4	0.2	0.6
Osteoarthritis (self-reported)	0.2	0.3	0.4	-0.4	-0.6
Hearing aid user	0.2	0.3	0.5	0.7	0.0
Mother’s age at death	0.2	0.2	0.4	0.6	-0.3
Commuting to job workplace: Public transport	0.2	0.2	0.3	-0.6	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.3	-0.5	0.6
Medication: Paracetamol	0.2	0.4	0.6	-0.8	0.3
Risk taking	0.2	0.3	0.4	0.7	0.4
Depression (Nagel 2018)	0.1	0.2	0.2	0.4	0.4
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	-0.4	-0.1
Reaction Time	0.1	0.2	0.3	-0.5	0.3
Breast Cancer	0.1	0.3	0.5	0.7	0.4
Ovarian Cancer	0.1	0.1	0.2	-0.3	0.4
LDL Cholesterol	0.1	0.2	0.3	0.1	0.6
Waist Hip Ratio (WHR)	0.1	0.2	0.3	0.5	0.5
Allergy or Eczema	0.1	0.2	0.3	-0.6	0.2
Average weekly spirits intake	0.1	0.1	0.2	-0.4	0.1
Sensitivity / hurt feelings	0.1	0.2	0.3	0.6	0.4
Angina	0.1	0.1	0.2	0.4	-0.3
Diabetes (father)	0.1	0.1	0.3	-0.0	-0.5
Relative age voice broke	0.1	0.1	0.2	-0.3	-0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.2	-0.0	-0.4
Forced vital capacity (FVC)	0.1	0.3	0.4	-0.7	0.5
Mouth/teeth dental problems	0.1	0.1	0.2	0.4	-0.1
Fluid intelligence score	0.1	0.2	0.2	-0.4	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.2	0.4	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.1	0.3	-0.2
Prospective memory result	0.1	0.1	0.2	0.1	-0.5
Glaucoma (self-reported)	0.1	0.1	0.2	-0.4	0.3
Number of full brothers	0.1	0.1	0.2	0.5	-0.1
Angina (self-reported)	0.1	0.2	0.3	0.5	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	-0.1	-0.4
Comparative height size at age 10	0.1	0.5	1.0	-0.2	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.2	0.3	0.5
Ever taken oral contraceptive pill	0.1	0.1	0.1	0.2	0.3
Alcohol drinker status: Never	0.1	0.1	0.1	-0.2	-0.3
Ever depressed for a whole week	0.1	0.2	0.3	0.3	0.5
Commuting to job workplace: Cycle	0.1	0.2	0.2	0.4	0.4
Major Depression (MDD)	0.0	0.0	0.0	-0.1	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.1	0.0	0.3
HDL Cholesterol	0.0	0.0	0.1	0.2	0.3
Hair Pigment	0.0	0.2	0.4	0.1	0.6
Tanning	0.0	0.0	0.0	0.1	0.0
Pack years adult smoking proportion	0.0	0.0	0.1	-0.1	-0.2
Current tobacco smoking	0.0	0.1	0.1	-0.1	-0.4
Medication: Simvastatin	0.0	0.0	0.0	0.1	-0.2
Hair/balding pattern: Pattern 3	0.0	0.0	0.1	-0.3	0.1
Peak expiratory flow (PEF)	0.0	0.0	0.1	0.3	0.1
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.1	-0.0	0.2
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.0	-0.2	0.0
Gout (self-reported)	0.0	0.0	0.0	-0.1	0.1
Medication: Allopurinol	0.0	0.0	0.0	0.2	-0.1
Mean time to correctly identify matches	0.0	0.1	0.1	-0.3	0.2
Number of full sisters	0.0	0.1	0.1	-0.2	-0.3
Leg pain on walking	0.0	0.0	0.1	0.3	0.1
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.0	-0.1	0.1
Smoking status: Current	0.0	0.1	0.1	0.3	0.1
Tinnitus: Yes, now most or all of the time	0.0	0.1	0.1	0.3	-0.1
Eye problems/disorders: Glaucoma	0.0	0.0	0.0	0.2	0.2
Pack years of smoking	0.0	0.1	0.1	0.2	-0.3

Hub : Genes

PRR14

Models

Trait associations