[Hub]/) : Traits : Arm predicted mass (right) :

chr2:23,453,834-29,344,127

Best TWAS P=7.07e-41 · Best GWAS P=4.44e-38 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GTF3C2 0.06 0.09 lasso 8 0.08 7.2e-10 4.57 -6.8 8.2e-12 0.72 0.28 0.72 TRUE
2 CommonMind Brain Pre-frontal Cortex IFT172 0.06 0.09 enet 16 0.09 3.9e-11 4.67 7.1 1.1e-12 -0.75 0.48 0.52 FALSE
3 CommonMind Brain Pre-frontal Cortex UBXN2A 0.22 0.18 enet 28 0.24 3.0e-28 -7.08 5.9 3.0e-09 -0.03 1.00 0.00 FALSE
4 GTEx Adipose Subcutaneous AC074117.10 0.06 0.04 lasso 5 0.02 4.8e-03 6.01 -6.3 3.1e-10 0.65 0.45 0.27 FALSE
5 GTEx Adipose Visceral Omentum PPM1G 0.06 0.01 lasso 5 0.01 1.1e-01 4.86 -5.4 6.8e-08 0.64 0.11 0.28 FALSE
6 GTEx Adipose Visceral Omentum AC074117.10 0.14 0.09 lasso 3 0.08 5.0e-05 5.47 -5.3 1.2e-07 0.60 0.85 0.08 FALSE
7 GTEx Artery Aorta NCOA1 0.15 0.00 enet 15 0.01 1.4e-01 -3.16 -5.4 7.7e-08 -0.01 0.07 0.04 FALSE
8 GTEx Artery Aorta AC074117.10 0.06 0.04 lasso 3 0.03 6.8e-03 5.47 -5.5 5.1e-08 0.58 0.24 0.14 FALSE
9 GTEx Artery Aorta RP11-373D23.3 0.23 0.12 enet 12 0.06 2.5e-04 5.14 -5.2 2.2e-07 0.06 0.66 0.03 FALSE
10 GTEx Artery Tibial PPM1G 0.06 0.02 lasso 4 0.03 2.3e-03 4.48 -5.9 3.6e-09 0.66 0.29 0.12 FALSE
11 GTEx Artery Tibial AC074117.10 0.13 0.14 lasso 5 0.13 1.1e-10 5.47 -5.7 1.0e-08 0.62 0.99 0.00 FALSE
12 GTEx Breast Mammary Tissue (Female) AC074117.10 0.06 0.01 lasso 2 0.04 2.7e-02 6.81 7.5 5.2e-14 -0.23 0.04 0.05 TRUE
13 GTEx Cells EBV-transformed lymphocytes NRBP1 0.11 0.13 enet 13 0.15 1.2e-05 4.72 -5.3 1.2e-07 0.62 0.57 0.10 FALSE
14 GTEx Cells EBV-transformed lymphocytes PFN4 0.18 0.13 lasso 12 0.12 8.9e-05 -4.41 -5.8 6.2e-09 0.06 0.32 0.08 FALSE
15 GTEx Cells Transformed fibroblasts NRBP1 0.09 0.08 lasso 3 0.08 7.8e-07 5.47 -6.0 2.6e-09 0.61 0.95 0.04 FALSE
16 GTEx Cells Transformed fibroblasts AC074117.10 0.21 0.19 enet 23 0.18 1.6e-13 6.01 -5.6 2.6e-08 0.66 0.87 0.13 FALSE
17 GTEx Colon Sigmoid DNMT3A 0.19 -0.01 lasso 8 0.00 4.5e-01 -1.34 -6.0 1.5e-09 0.06 0.07 0.12 TRUE
18 GTEx Colon Sigmoid AC074117.10 0.13 0.18 lasso 3 0.14 1.1e-05 5.47 -5.3 9.8e-08 0.60 0.85 0.08 FALSE
19 GTEx Colon Transverse UBXN2A 0.11 0.01 enet 8 0.03 8.7e-03 -6.44 -6.9 5.7e-12 -0.06 0.08 0.68 FALSE
20 GTEx Esophagus Gastroesophageal Junction PFN4 0.13 0.01 lasso 12 0.01 9.7e-02 -5.78 -5.3 8.7e-08 0.08 0.11 0.06 TRUE
21 GTEx Esophagus Gastroesophageal Junction AC074117.10 0.12 0.13 enet 9 0.09 4.9e-04 4.88 -6.4 1.2e-10 0.64 0.43 0.30 TRUE
22 GTEx Esophagus Gastroesophageal Junction RP11-373D23.3 0.17 0.01 enet 15 0.04 1.2e-02 5.32 -6.1 1.1e-09 0.28 0.07 0.31 FALSE
23 GTEx Esophagus Mucosa TP53I3 0.16 0.03 enet 23 0.06 8.2e-05 1.17 -6.4 1.9e-10 0.05 0.11 0.10 FALSE
24 GTEx Esophagus Mucosa AC074117.10 0.12 0.14 lasso 8 0.14 2.1e-09 6.01 -7.9 2.3e-15 0.74 0.94 0.06 FALSE
25 GTEx Esophagus Muscularis NCOA1 0.11 0.01 enet 9 0.01 5.8e-02 -3.36 -6.2 4.5e-10 0.01 0.06 0.28 FALSE
26 GTEx Esophagus Muscularis NRBP1 0.07 0.04 lasso 6 0.04 1.3e-03 6.01 -8.3 1.1e-16 0.82 0.01 0.97 FALSE
27 GTEx Esophagus Muscularis AC074117.10 0.17 0.14 enet 5 0.09 6.6e-06 6.01 -6.3 3.1e-10 0.65 0.73 0.26 FALSE
28 GTEx Heart Atrial Appendage UBXN2A 0.08 0.02 lasso 3 0.02 5.2e-02 -6.14 -6.8 9.5e-12 0.02 0.23 0.28 FALSE
29 GTEx Heart Atrial Appendage PFN4 0.22 0.06 lasso 7 0.10 2.8e-05 1.17 -5.3 9.6e-08 0.12 0.63 0.06 FALSE
30 GTEx Heart Left Ventricle PFN4 0.23 0.28 lasso 6 0.28 4.1e-15 -4.40 -5.6 2.2e-08 0.05 1.00 0.00 FALSE
31 GTEx Lung NCOA1 0.12 0.04 lasso 7 0.06 1.9e-05 -3.86 -6.5 6.5e-11 0.01 0.52 0.02 TRUE
32 GTEx Lung RP11-373D23.3 0.08 0.00 enet 21 0.02 2.3e-02 3.94 -6.2 4.8e-10 0.23 0.13 0.43 FALSE
33 GTEx Muscle Skeletal GPN1 0.06 0.02 enet 9 0.02 2.9e-03 -1.92 -6.0 2.2e-09 0.43 0.29 0.07 FALSE
34 GTEx Nerve Tibial NRBP1 0.06 0.00 enet 9 0.02 2.0e-02 6.01 -6.1 1.4e-09 0.61 0.28 0.61 FALSE
35 GTEx Ovary AC074117.10 0.16 0.04 enet 9 0.05 2.0e-02 4.86 -7.8 7.3e-15 0.77 0.04 0.80 FALSE
36 GTEx Pituitary AC074117.10 0.23 0.23 lasso 8 0.29 5.6e-08 4.06 -5.2 2.3e-07 0.66 0.34 0.57 FALSE
37 GTEx Skin Sun Exposed Lower leg SLC4A1AP 0.04 0.01 lasso 3 0.02 1.7e-02 4.69 5.2 2.5e-07 -0.60 0.21 0.11 FALSE
38 GTEx Small Intestine Terminal Ileum UBXN2A 0.18 0.08 enet 33 0.16 2.5e-04 -6.35 -5.7 1.3e-08 -0.08 0.03 0.89 FALSE
39 GTEx Spleen UBXN2A 0.31 0.11 enet 19 0.17 4.1e-05 7.88 -7.8 6.7e-15 -0.05 0.04 0.92 TRUE
40 GTEx Stomach AC074117.10 0.06 0.01 lasso 7 0.01 7.8e-02 6.01 8.5 2.3e-17 -0.36 0.20 0.08 FALSE
41 GTEx Testis NRBP1 0.16 0.09 lasso 3 0.06 1.8e-03 6.01 -8.3 1.0e-16 0.80 0.03 0.96 FALSE
42 GTEx Testis AC074117.10 0.14 0.08 lasso 6 0.12 4.5e-06 4.92 -9.3 1.3e-20 0.85 0.05 0.94 FALSE
43 GTEx Thyroid FNDC4 0.24 0.10 enet 23 0.16 2.2e-12 7.99 11.0 6.2e-28 -0.69 0.67 0.33 FALSE
44 GTEx Thyroid AC074117.10 0.17 0.14 lasso 4 0.15 2.7e-11 4.88 -5.1 2.9e-07 0.61 1.00 0.00 FALSE
45 GTEx Thyroid RP11-373D23.3 0.16 0.07 enet 19 0.04 2.6e-04 4.88 -7.2 7.9e-13 0.15 0.50 0.16 TRUE
46 GTEx Vagina AC074117.10 0.14 0.04 enet 13 0.06 1.4e-02 4.11 -7.2 7.5e-13 0.72 0.08 0.57 FALSE
47 GTEx Whole Blood UBXN2A 0.17 0.07 lasso 8 0.09 2.1e-08 -1.03 -5.4 8.3e-08 -0.08 0.04 0.96 FALSE
48 METSIM Adipose BRE 0.03 0.00 blup 534 0.00 1.3e-01 0.19 -5.6 2.3e-08 0.30 0.10 0.05 FALSE
49 METSIM Adipose KRTCAP3 0.05 0.01 blup 288 0.03 1.6e-05 4.69 5.7 9.7e-09 -0.52 0.96 0.03 FALSE
50 METSIM Adipose NRBP1 0.06 0.09 lasso 3 0.08 1.6e-12 6.01 -6.4 1.4e-10 0.67 1.00 0.00 FALSE
51 METSIM Adipose PREB 0.04 0.01 bslmm 302 0.02 5.6e-04 3.13 5.5 4.3e-08 -0.36 0.07 0.30 FALSE
52 METSIM Adipose SLC5A6 0.03 0.02 bslmm 298 0.01 3.9e-03 2.51 -5.2 1.6e-07 0.43 0.25 0.04 FALSE
53 METSIM Adipose UBXN2A 0.07 0.03 bslmm 403 0.06 5.3e-10 -6.37 -5.4 8.5e-08 0.00 0.90 0.10 FALSE
54 ROSMAP Brain Pre-frontal Cortex IFT172 0.07 0.02 blup 287 0.03 5.8e-05 5.47 7.4 1.8e-13 -0.63 0.43 0.49 FALSE
55 ROSMAP Brain Pre-frontal Cortex KCNK3 0.24 0.15 lasso 3 0.15 6.5e-19 5.31 -5.8 9.0e-09 0.09 0.01 0.99 TRUE
56 ROSMAP Brain Pre-frontal Cortex UBXN2A 0.03 0.01 lasso 4 0.02 2.2e-03 -6.10 6.3 2.8e-10 -0.04 0.35 0.02 FALSE
57 ROSMAP Brain Pre-frontal Cortex FTH1P3 0.04 0.01 bslmm 280 0.02 2.8e-03 6.01 -6.1 9.7e-10 0.65 0.04 0.70 FALSE
58 YFS Blood EIF2B4 0.01 0.00 enet 9 0.00 8.5e-02 2.13 5.5 4.6e-08 -0.52 0.04 0.03 FALSE
59 YFS Blood MRPL33 0.02 0.01 blup 385 0.01 6.4e-05 6.27 -5.7 1.0e-08 0.22 0.97 0.00 FALSE
60 YFS Blood NRBP1 0.01 0.01 lasso 6 0.01 9.1e-06 4.92 -5.9 2.9e-09 0.61 0.99 0.00 FALSE
61 The Cancer Genome Atlas Bladder Urothelial Carcinoma PPM1G 0.03 0.02 blup 31 0.02 8.8e-03 4.79 -5.9 4.0e-09 0.66 0.03 0.51 FALSE
62 The Cancer Genome Atlas Breast Invasive Carcinoma FKBP1B 0.04 0.02 blup 41 0.02 3.6e-05 -4.41 5.5 4.5e-08 -0.08 0.43 0.06 FALSE
63 The Cancer Genome Atlas Breast Invasive Carcinoma GPN1 0.06 0.02 lasso 6 0.02 7.2e-05 -9.92 -8.4 5.3e-17 0.54 0.00 0.99 FALSE
64 The Cancer Genome Atlas Breast Invasive Carcinoma SNX17 0.08 0.01 blup 25 0.02 6.6e-05 2.94 6.5 1.0e-10 -0.55 0.02 0.34 FALSE
65 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma SUPT7L 0.06 0.03 blup 29 0.05 2.0e-03 8.25 5.8 5.5e-09 -0.04 0.04 0.04 TRUE
66 The Cancer Genome Atlas Glioblastoma Multiforme NRBP1 0.15 0.10 lasso 2 0.10 5.8e-04 6.01 -6.1 1.2e-09 0.67 0.02 0.09 FALSE
67 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC4A1AP 0.02 0.03 lasso 2 0.03 3.7e-04 -1.31 5.3 1.2e-07 -0.47 0.01 0.83 FALSE
68 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SUPT7L 0.05 0.02 blup 28 0.04 5.2e-05 8.27 10.4 2.1e-25 -0.40 0.19 0.14 TRUE
69 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FNDC4 0.13 0.06 lasso 2 0.05 1.1e-03 -12.90 13.4 7.1e-41 -0.99 0.00 0.96 TRUE
70 The Cancer Genome Atlas Brain Lower Grade Glioma UBXN2A 0.04 0.04 lasso 1 0.03 1.4e-04 -6.08 6.1 1.2e-09 -0.03 0.36 0.14 FALSE
71 The Cancer Genome Atlas Pancreatic Adenocarcinoma POMC 0.22 0.05 blup 37 0.03 2.1e-02 -4.54 -5.4 5.7e-08 0.01 0.00 0.72 FALSE
72 The Cancer Genome Atlas Prostate Adenocarcinoma NRBP1 0.03 0.03 blup 30 0.03 2.2e-04 4.11 -5.6 2.2e-08 0.64 0.67 0.08 FALSE
73 The Cancer Genome Atlas Skin Cutaneous Melanoma SLC4A1AP 0.17 0.05 blup 26 0.08 4.4e-03 -9.92 5.2 2.5e-07 -0.47 0.01 0.72 FALSE
74 The Cancer Genome Atlas Thyroid Carcinoma FNDC4 0.24 0.09 enet 9 0.17 1.9e-16 8.18 10.9 1.5e-27 -0.70 0.41 0.59 FALSE
75 The Cancer Genome Atlas Thyroid Carcinoma GCKR 0.18 0.08 enet 5 0.13 1.7e-12 7.99 10.4 2.7e-25 -0.64 0.91 0.09 FALSE
76 The Cancer Genome Atlas Thyroid Carcinoma IFT172 0.08 0.01 blup 43 0.02 6.1e-03 8.92 10.3 9.0e-25 -0.54 0.02 0.27 FALSE
77 The Cancer Genome Atlas Thyroid Carcinoma NRBP1 0.03 0.01 blup 30 0.02 5.3e-03 6.01 -5.2 1.6e-07 0.62 0.32 0.05 FALSE