[Hub]/) : Traits : Height :

chr1:152,817,053-157,406,190

Best TWAS P=8.96e-35 · Best GWAS P=5.69e-29 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADAR 0.12 0.13 lasso 4 0.13 3.0e-15 5.044 -5.9 4.3e-09 -0.02 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex MRPL24 0.05 0.01 enet 10 0.03 2.9e-04 6.138 -6.4 1.4e-10 -0.01 0.27 0.26 TRUE
3 GTEx Adipose Subcutaneous RP1-178F15.4 0.20 0.21 enet 16 0.25 2.3e-20 -4.992 -5.2 1.6e-07 -0.04 0.30 0.70 FALSE
4 GTEx Artery Aorta RP1-178F15.4 0.16 0.17 lasso 9 0.19 6.0e-11 -4.992 -5.2 1.8e-07 -0.05 0.35 0.65 FALSE
5 GTEx Artery Tibial MEF2D 0.17 0.10 enet 17 0.09 2.6e-07 5.790 6.0 1.6e-09 0.06 0.18 0.82 FALSE
6 GTEx Artery Tibial S100A13 0.14 0.04 lasso 8 0.08 1.2e-06 -5.028 -5.4 5.3e-08 -0.07 0.34 0.61 FALSE
7 GTEx Artery Tibial RP1-178F15.5 0.14 0.04 lasso 8 0.06 1.7e-05 -5.028 -5.5 3.4e-08 -0.06 0.30 0.53 FALSE
8 GTEx Brain Caudate basal ganglia S100A13 0.14 0.08 lasso 3 0.02 9.2e-02 -4.948 5.9 4.6e-09 0.05 0.04 0.80 FALSE
9 GTEx Brain Cerebellar Hemisphere DCST2 0.45 0.10 lasso 6 0.16 6.6e-05 -2.416 7.7 1.9e-14 0.75 0.01 0.96 FALSE
10 GTEx Brain Frontal Cortex BA9 S100A13 0.21 0.04 enet 13 0.12 3.9e-04 -4.920 5.2 2.6e-07 0.00 0.11 0.40 FALSE
11 GTEx Brain Frontal Cortex BA9 RP1-178F15.5 0.21 0.06 enet 13 0.16 4.7e-05 -5.194 5.2 2.7e-07 0.00 0.12 0.38 FALSE
12 GTEx Brain Nucleus accumbens basal ganglia DCST2 0.28 0.04 lasso 5 0.13 2.0e-04 11.171 6.5 7.6e-11 0.69 0.02 0.90 TRUE
13 GTEx Breast Mammary Tissue S100A14 0.14 0.04 enet 17 0.05 2.0e-03 -5.016 -5.5 4.4e-08 -0.03 0.27 0.61 FALSE
14 GTEx Breast Mammary Tissue (Female) FAM189B 0.05 -0.01 lasso 2 0.00 4.8e-01 -6.531 6.5 7.3e-11 0.09 0.04 0.07 FALSE
15 GTEx Cells EBV-transformed lymphocytes S100A13 0.19 0.19 lasso 6 0.19 6.2e-07 -5.194 -5.2 1.5e-07 -0.04 0.22 0.74 FALSE
16 GTEx Esophagus Mucosa ADAM15 0.11 0.02 enet 16 0.04 1.5e-03 -4.739 -7.3 3.3e-13 -0.43 0.13 0.78 FALSE
17 GTEx Esophagus Mucosa MUC1 0.17 0.20 lasso 4 0.18 5.6e-12 -6.709 -6.3 2.4e-10 -0.12 1.00 0.00 FALSE
18 GTEx Esophagus Mucosa RP1-178F15.4 0.10 0.12 lasso 6 0.11 6.1e-08 -4.992 -5.2 1.5e-07 -0.04 0.31 0.68 FALSE
19 GTEx Heart Atrial Appendage RP1-178F15.4 0.25 0.25 enet 27 0.26 7.4e-12 -4.990 -5.1 2.9e-07 -0.05 0.35 0.65 FALSE
20 GTEx Heart Left Ventricle S100A14 0.10 0.07 lasso 3 0.05 7.1e-04 -5.194 5.4 7.7e-08 0.02 0.15 0.64 FALSE
21 GTEx Liver S100A13 0.23 0.06 enet 60 0.05 1.3e-02 5.837 6.0 1.5e-09 0.02 0.03 0.78 TRUE
22 GTEx Liver RP1-178F15.4 0.16 0.20 lasso 3 0.17 1.7e-05 -5.031 -5.2 1.9e-07 -0.05 0.22 0.63 FALSE
23 GTEx Nerve Tibial S100A16 0.09 0.08 lasso 4 0.09 4.2e-07 4.366 -5.1 3.0e-07 -0.07 0.34 0.65 FALSE
24 GTEx Pancreas RRNAD1 0.22 0.05 enet 25 0.03 2.7e-02 4.062 6.2 4.9e-10 -0.03 0.03 0.72 FALSE
25 GTEx Pancreas MRPL24 0.19 0.01 enet 16 0.01 1.6e-01 4.389 6.7 2.1e-11 -0.03 0.03 0.58 TRUE
26 GTEx Pancreas THBS3 0.36 0.14 lasso 6 0.12 1.0e-05 2.000 -5.1 2.8e-07 -0.34 0.18 0.54 FALSE
27 GTEx Pancreas RP11-263K19.4 0.22 0.06 enet 23 0.05 3.1e-03 2.000 -7.5 4.6e-14 -0.43 0.06 0.49 FALSE
28 GTEx Pancreas RP1-178F15.4 0.27 0.02 enet 22 0.12 8.9e-06 -4.770 -5.3 1.2e-07 -0.02 0.22 0.44 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic GBAP1 0.15 0.06 lasso 4 0.06 3.6e-04 -6.722 5.3 9.5e-08 0.11 0.54 0.04 FALSE
30 GTEx Skin Sun Exposed Lower leg ADAM15 0.14 0.09 lasso 4 0.08 6.1e-07 11.171 -12.3 9.0e-35 -0.96 0.00 1.00 TRUE
31 GTEx Skin Sun Exposed Lower leg RP1-178F15.5 0.10 0.06 lasso 12 0.05 2.4e-05 -5.016 -5.6 1.8e-08 -0.03 0.34 0.65 FALSE
32 GTEx Spleen SHC1 0.22 0.14 lasso 2 0.08 4.0e-03 -5.582 -5.8 5.0e-09 -0.15 0.14 0.05 FALSE
33 GTEx Stomach RP1-178F15.4 0.29 0.10 enet 22 0.17 1.3e-08 -4.720 -5.3 1.0e-07 -0.04 0.39 0.60 FALSE
34 GTEx Testis MUC1 0.20 0.02 lasso 7 0.07 7.5e-04 -6.722 -7.0 2.1e-12 -0.11 0.27 0.05 TRUE
35 GTEx Thyroid RP1-178F15.4 0.13 0.03 lasso 4 0.04 6.8e-04 -5.016 -5.1 2.8e-07 -0.05 0.34 0.65 FALSE
36 METSIM Adipose S100A5 0.05 0.00 blup 422 0.02 6.5e-04 -0.064 -5.4 5.9e-08 0.04 0.10 0.07 FALSE
37 NTR Blood ZBTB7B 0.02 0.02 lasso 1 0.01 5.4e-05 6.399 6.4 1.6e-10 0.67 0.87 0.03 FALSE
38 ROSMAP Brain Pre-frontal Cortex SLC50A1 0.06 0.02 bslmm 331 0.03 4.3e-05 -6.709 -7.0 1.8e-12 -0.27 0.65 0.04 FALSE
39 YFS Blood ADAR 0.04 0.05 enet 14 0.05 4.3e-17 -7.424 8.6 8.1e-18 0.03 1.00 0.00 TRUE
40 YFS Blood LMNA 0.05 0.04 enet 8 0.05 1.1e-14 6.294 7.2 4.1e-13 -0.04 0.45 0.55 TRUE
41 YFS Blood MRPL24 0.08 0.03 enet 18 0.04 4.3e-12 4.627 -6.3 2.4e-10 -0.01 1.00 0.00 FALSE
42 YFS Blood MSTO1 0.13 0.08 blup 282 0.10 1.9e-29 6.264 -6.6 3.5e-11 -0.02 0.99 0.01 FALSE
43 The Cancer Genome Atlas Bladder Urothelial Carcinoma S100A16 0.03 0.02 blup 34 0.03 2.6e-03 -4.948 -5.2 1.7e-07 -0.05 0.02 0.86 FALSE
44 The Cancer Genome Atlas Bladder Urothelial Carcinoma S100A1 0.07 0.14 lasso 6 0.13 3.6e-11 -4.948 -5.2 2.6e-07 -0.04 0.02 0.98 FALSE
45 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM46 0.03 0.00 blup 33 0.02 3.6e-03 -6.709 -5.5 4.3e-08 -0.11 0.02 0.34 FALSE
46 The Cancer Genome Atlas Breast Invasive Carcinoma SEMA4A 0.01 0.00 blup 51 0.01 1.2e-02 3.243 7.2 5.0e-13 -0.05 0.01 0.16 FALSE
47 The Cancer Genome Atlas Colon Adenocarcinoma LMNA 0.07 0.00 blup 55 0.01 9.1e-02 2.773 5.6 2.4e-08 0.04 0.02 0.06 FALSE
48 The Cancer Genome Atlas Glioblastoma Multiforme S100A13 0.09 0.05 blup 35 0.03 3.6e-02 -4.948 5.2 2.5e-07 0.05 0.02 0.68 FALSE
49 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RAG1AP1 0.07 0.00 blup 76 0.00 2.9e-01 -2.844 -6.8 7.6e-12 -0.17 0.02 0.13 FALSE
50 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C1orf77 0.02 0.02 blup 38 0.02 1.3e-03 4.557 5.1 2.8e-07 0.04 0.02 0.80 FALSE
51 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ZBTB7B 0.05 0.06 lasso 2 0.05 1.8e-06 11.171 -11.2 5.5e-29 -1.00 0.00 1.00 FALSE
52 The Cancer Genome Atlas Prostate Adenocarcinoma GBA 0.05 0.01 lasso 2 0.01 2.3e-02 6.989 -5.8 5.8e-09 -0.07 0.00 0.76 TRUE
53 The Cancer Genome Atlas Prostate Adenocarcinoma UBQLN4 0.11 0.00 blup 33 0.04 3.8e-05 5.516 -5.8 8.7e-09 -0.01 0.00 0.97 FALSE
54 The Cancer Genome Atlas Stomach Adenocarcinoma S100A13 0.03 0.01 blup 35 0.03 3.8e-03 4.990 5.1 2.8e-07 0.05 0.02 0.73 FALSE
55 The Cancer Genome Atlas Testicular Germ Cell Tumors PMF1 0.17 0.10 blup 62 0.08 6.5e-04 3.728 -5.7 1.2e-08 0.07 0.01 0.44 TRUE