Hub : Genes

S100A14

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Breast Mammary Tissue	0.1430	0.0540	1.1e-03	0.038	NA	0.046	NA	0.037	4.9e-03	NA	2.0e-03	NA	5.5e-03
2	GTEx	Breast Mammary Tissue (Male)	0.2146	0.0992	9.8e-03	0.069	NA	0.084	NA	0.063	1.1e-02	NA	5.4e-03	NA	1.4e-02
3	GTEx	Esophagus Mucosa	0.2310	0.0510	2.1e-11	0.164	NA	0.177	NA	0.177	4.0e-11	NA	6.2e-12	NA	5.8e-12
4	GTEx	Heart Atrial Appendage	0.2210	0.0830	2.1e-04	0.010	NA	0.106	NA	0.098	1.2e-01	NA	1.8e-05	NA	3.8e-05
5	GTEx	Heart Left Ventricle	0.0965	0.0423	5.1e-03	0.066	NA	0.021	NA	0.055	2.2e-04	NA	2.5e-02	NA	7.1e-04
6	GTEx	Thyroid	0.3220	0.0690	4.3e-13	0.235	NA	0.242	NA	0.248	6.1e-18	NA	1.6e-18	NA	5.8e-19
7	TCGA	Bladder Urothelial Carcinoma	0.0510	0.0330	4.3e-04	0.051	0.022	0.046	NA	0.044	3.7e-05	5.7e-03	8.3e-05	NA	1.3e-04
8	TCGA	Breast Invasive Carcinoma	0.0275	0.0171	1.5e-06	0.023	0.025	0.016	NA	0.022	1.4e-05	5.4e-06	2.8e-04	NA	1.8e-05
9	TCGA	Colon Adenocarcinoma	0.0830	0.0690	2.5e-03	0.069	0.019	0.042	NA	0.063	7.8e-05	2.6e-02	1.9e-03	NA	1.6e-04
10	TCGA	Glioblastoma Multiforme	0.1370	0.0930	6.1e-03	0.054	0.082	0.054	NA	0.067	9.7e-03	1.8e-03	9.6e-03	NA	4.5e-03
11	TCGA	Brain Lower Grade Glioma	0.0315	0.0183	7.5e-05	0.043	0.031	0.034	NA	0.044	1.1e-05	1.7e-04	8.3e-05	NA	8.5e-06
12	TCGA	Lung Squamous Cell Carcinoma	0.0474	0.0264	2.3e-04	0.034	0.030	0.031	NA	0.028	7.9e-05	2.1e-04	1.6e-04	NA	3.4e-04
13	TCGA	Pancreatic Adenocarcinoma	0.1550	0.0740	1.4e-06	0.143	0.120	0.131	NA	0.118	1.4e-06	1.1e-05	4.1e-06	NA	1.3e-05
14	TCGA	Prostate Adenocarcinoma	0.0225	0.0142	1.6e-03	0.038	0.029	0.035	NA	0.037	7.3e-05	4.6e-04	1.4e-04	NA	8.7e-05
15	TCGA	Stomach Adenocarcinoma	0.0590	0.0380	1.6e-03	0.047	0.044	0.042	NA	0.042	2.5e-04	3.9e-04	5.2e-04	NA	5.4e-04
16	TCGA	Testicular Germ Cell Tumors	0.1540	0.0680	1.1e-07	0.237	0.176	0.233	NA	0.220	6.7e-09	8.3e-07	9.6e-09	NA	2.7e-08
17	TCGA	Thyroid Carcinoma	0.1710	0.0740	0.0e+00	0.169	0.171	0.163	NA	0.177	3.5e-16	2.1e-16	1.1e-15	NA	5.4e-17

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.5	0.8	1.4	-0.8	-1.2	0.7	-0.1	0.7	0.7	-1.2	-0.9	-1.1	-0.9	-1.0	-0.8	-1.0	0.7	-0.6	-1.2	0.8
Bipolar Disorder or Schizophrenia	0.8	2.0	2.9	-1.7	-1.6	1.3	0.5	1.3	1.4	-1.2	-1.7	-1.6	-1.6	-1.6	-1.5	-1.4	1.4	-1.2	-1.3	1.4
Depressed Affect (Nagel 2018)	0.8	1.7	2.8	0.8	1.3	-1.6	-0.1	-1.2	-1.0	1.6	1.3	1.4	1.3	1.2	1.1	1.5	-0.8	1.7	1.6	-1.4
Depression (Nagel 2018)	0.1	0.1	0.6	0.0	-0.1	-0.1	-0.1	0.4	0.5	0.4	-0.2	0.1	-0.1	-0.1	-0.2	0.2	0.8	-0.0	0.4	0.2
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.8	0.2	0.5	-0.7	-1.7	-0.3	-0.8	0.3	0.3	0.6	0.7	0.7	0.8	0.5	-0.8	0.9	0.3	-0.6
Neuroticism (Nagel 2018)	0.1	0.3	1.8	-0.8	-0.6	0.3	1.3	0.6	0.7	-0.0	-0.5	-0.2	-0.4	-0.3	-0.3	-0.2	1.0	-0.0	-0.1	0.4
Schizophrenia (2018)	0.7	1.4	2.2	-1.5	-1.1	1.2	0.9	1.1	1.3	-0.6	-1.4	-1.1	-1.4	-1.3	-1.3	-1.0	1.2	-1.1	-0.8	1.2
Schizophrenia vs Biploar Disorder	0.7	0.9	1.5	0.9	1.1	-0.9	-0.7	-1.1	-1.0	1.2	1.1	1.0	0.8	0.9	0.9	1.0	-1.1	0.4	1.1	-0.9
Worry (Nagel 2018)	3.4	7.2	9.6	-2.9	-3.1	2.6	2.4	3.0	2.8	-2.5	-2.9	-2.5	-2.8	-2.4	-2.2	-2.5	3.1	-2.3	-2.5	2.7
Alzheimer’s Disease (in mother)	1.3	1.5	2.9	-0.8	-1.2	1.1	0.7	0.9	1.2	-1.6	-0.8	-1.1	-1.5	-1.3	-1.4	-1.4	1.1	-1.7	-1.5	1.2
Alzheimer’s Disease (in father)	0.4	0.4	1.3	-0.7	-0.7	0.4	0.5	1.1	0.7	-0.6	-1.1	-0.6	-0.4	-0.5	-0.2	-0.4	0.8	0.2	-0.6	0.5
Alzheimer’s Disease (including proxy)	1.2	1.8	2.4	-1.1	-1.2	1.2	1.0	1.5	1.6	-1.5	-1.4	-1.1	-1.4	-1.3	-1.4	-1.3	1.6	-1.3	-1.4	1.4
Crohns Disease (2017)	0.1	0.2	0.6	0.8	0.7	-0.5	-0.0	-0.4	-0.1	0.3	0.7	0.5	0.3	0.3	0.2	0.5	-0.1	-0.2	0.5	-0.3
Irritable Bowel Disease (IBD)	0.0	0.1	0.6	0.1	-0.1	0.3	0.3	0.3	0.4	-0.1	-0.2	-0.4	-0.4	-0.4	-0.3	-0.1	0.4	-0.8	-0.1	0.3
Ulcerative Colitis (UC)	1.0	1.9	3.4	-1.3	-1.5	1.7	0.6	1.3	1.3	-1.2	-1.5	-1.8	-1.5	-1.6	-1.2	-1.3	1.3	-1.6	-1.3	1.3
Major Depression (MDD)	1.7	2.0	2.8	-1.1	-1.3	1.6	0.6	1.3	1.7	-1.5	-1.3	-1.6	-1.5	-1.6	-1.5	-1.5	1.4	-1.4	-1.5	1.5
Reaction Time	0.0	0.1	0.2	-0.2	0.5	-0.1	0.0	0.4	0.3	0.4	0.0	0.3	-0.1	0.1	-0.1	0.1	0.3	-0.3	0.3	0.0
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.5	-1.0	-1.1	0.7	-1.0	0.7	0.4	-1.2	-1.1	-0.9	-0.5	-0.5	-0.2	-0.8	0.5	-0.2	-1.1	0.6
Breast Cancer	0.0	0.1	0.4	-0.5	-0.3	0.3	-0.2	0.1	0.2	-0.1	-0.7	-0.3	-0.3	-0.3	-0.4	-0.2	0.0	-0.3	-0.0	0.2
Ovarian Cancer	1.8	2.3	4.4	-2.1	-1.7	1.6	1.3	1.6	1.6	-1.3	-1.8	-1.5	-1.4	-1.5	-1.5	-1.4	1.7	-0.9	-1.4	1.5
Prostate Cancer	1.3	1.8	3.9	1.4	1.6	-1.3	0.4	-0.4	-0.8	1.8	0.8	1.9	1.4	1.4	0.9	1.7	-0.5	1.4	2.0	-1.3
Age at First Birth	3.1	4.6	18.7	3.1	3.1	-3.5	-4.3	-3.6	-3.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.5	0.5	2.1	-1.2	-1.3	1.2	0.0	1.2	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.2	0.3	1.1	0.8	0.9	-1.0	-1.1	-0.7	-0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	1.0	1.1	4.8	-2.2	-1.9	2.1	0.0	1.6	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.2	0.4	1.7	-0.0	0.4	-0.8	0.0	-0.2	-0.4	0.5	0.3	0.8	0.7	0.8	0.7	0.7	-0.3	1.3	0.6	-0.6
Mean Putamen Volume	0.2	0.3	1.2	0.0	0.2	-0.5	-1.1	0.0	-0.1	0.1	0.2	0.5	0.5	0.7	0.6	0.3	0.4	1.0	0.2	-0.1
Fasting Glucose	0.5	0.6	2.1	-1.4	-1.4	1.3	0.8	1.1	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HbA1C	0.3	0.3	1.2	-0.4	-1.0	1.1	-0.4	1.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	1.9	3.2	11.1	3.3	3.1	-3.2	-2.2	-2.9	-3.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	1.1	1.7	7.4	-1.8	-2.4	2.7	1.4	2.1	2.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lupus	0.0	0.0	0.3	-0.1	0.1	0.1	-0.5	-0.1	-0.3	0.1	0.2	-0.1	0.3	0.2	0.2	0.2	-0.2	0.3	0.2	-0.1
Neuroticism (2016)	1.4	2.0	2.6	1.2	1.5	-1.6	1.3	-1.3	-1.3	1.4	1.6	1.5	1.4	1.6	1.6	1.5	-1.2	1.4	1.5	-1.3
Primary Biliary Cirrhosis	0.4	0.6	1.6	-0.7	-0.8	0.7	0.1	1.2	0.8	-0.7	-0.8	-0.7	-0.8	-0.6	-0.7	-0.8	0.8	-0.5	-0.7	0.9
Rheumatoid Arthritis	1.1	1.5	3.5	1.4	1.2	-1.3	-1.2	-1.7	-1.6	0.8	1.9	0.9	1.0	1.1	1.2	0.8	-1.7	0.1	0.7	-1.1
Schizophrenia (2014)	0.2	0.4	1.1	-1.1	-0.6	0.7	-0.4	0.6	0.6	-0.1	-0.9	-0.7	-0.7	-0.7	-0.5	-0.4	0.5	-0.4	-0.2	0.5
Triglycerides	0.8	1.3	6.4	-1.4	-2.0	2.5	1.8	1.7	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	2.8	3.2	11.2	-3.0	-3.1	3.0	2.2	3.3	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.4	0.6	0.8	-0.4	-0.8	0.9	0.3	0.7	0.8	-0.9	-0.7	-0.9	-0.8	-0.9	-0.8	-0.8	0.7	-0.7	-0.8	0.8
Blood Eosinophil Count	0.1	0.7	3.5	-1.9	-1.4	0.4	1.2	0.2	0.4	-0.5	-1.2	-0.9	-0.5	-1.0	-0.3	-0.3	0.4	1.0	-0.6	0.2
Blood Platelet Count	3.6	41.6	52.0	-7.0	-6.5	6.7	3.9	6.9	7.0	-5.8	-7.2	-6.3	-6.7	-6.6	-6.7	-6.3	7.0	-5.5	-5.8	6.8
Blood Red Count	0.0	0.4	1.7	1.3	1.0	-0.7	-0.1	-0.4	0.0	0.6	0.9	0.7	0.6	0.2	0.1	0.6	-0.1	0.2	0.7	-0.3
Blood White Count	0.8	5.9	13.1	-3.6	-3.1	2.5	1.8	2.1	2.0	-2.4	-2.8	-2.8	-2.5	-2.4	-1.8	-2.4	2.0	-1.1	-2.5	2.2
Heel T-Score	0.2	1.3	2.9	-1.1	-1.1	1.3	0.3	1.2	1.4	-0.9	-1.4	-0.9	-1.0	-1.2	-1.3	-0.9	1.7	-0.7	-0.8	1.0
BMI	0.1	0.4	1.8	0.0	0.7	-0.7	-1.3	-0.6	-0.3	1.0	0.2	0.9	0.5	0.6	0.2	0.6	-0.3	0.7	0.8	-0.4
Height	1.1	21.0	29.9	-5.5	-4.9	4.6	3.2	5.4	4.7	-4.7	-4.8	-4.6	-4.4	-4.1	-3.9	-4.7	4.9	-3.3	-4.7	4.9
Waist Hip Ratio (WHR)	1.0	4.3	7.1	1.9	2.2	-2.3	-0.4	-1.8	-2.0	2.0	2.1	2.2	2.3	2.1	2.2	2.1	-2.0	2.7	1.9	-2.1
Systolic Blood Pressure	0.1	0.5	1.8	-1.3	-0.4	0.6	1.3	0.7	0.7	-0.5	-0.6	-0.4	0.0	-0.6	-0.5	-0.4	0.8	0.7	-0.5	0.4
Smoking Status	0.2	0.4	1.1	0.9	0.8	-1.1	-0.3	-0.5	-0.7	0.3	0.6	0.8	0.6	0.7	0.6	0.5	-0.5	1.0	0.4	-0.6
Allergy or Eczema	2.2	5.8	9.6	-1.7	-3.1	2.6	1.5	2.8	2.3	-1.8	-3.1	-2.6	-2.7	-2.7	-2.5	-2.3	1.9	-2.2	-2.0	2.5
Cardiovascular Disease	0.2	0.7	4.9	-1.0	-0.6	0.5	2.2	0.8	0.6	-0.6	-0.4	-0.6	-0.6	-0.5	-0.5	-0.7	0.7	-0.3	-0.7	0.7
Hypothyroidism (self reported)	0.1	0.3	1.3	0.2	0.3	-0.2	1.2	0.4	-0.1	0.5	0.1	0.3	0.6	0.5	0.6	0.6	0.2	1.1	0.5	-0.3
Respiratory disease	1.1	2.4	4.7	-1.8	-1.9	1.6	1.3	1.5	1.5	-1.2	-1.3	-1.9	-1.5	-2.2	-1.7	-1.6	1.0	-1.0	-1.4	1.6
Type 2 Diabetes (T2D) (2018)	0.9	1.7	3.1	1.5	1.1	-1.2	-1.8	-1.6	-1.6	0.9	1.3	1.0	1.0	1.3	1.6	1.2	-1.4	0.7	0.9	-1.4
Lung FEV1/FVC ratio	0.0	0.1	1.1	-0.3	-0.3	0.2	1.1	0.3	0.1	-0.2	-0.4	-0.1	-0.0	0.1	0.2	0.2	0.5	0.4	0.1	-0.3
Lung FVC	2.1	10.9	15.9	-2.4	-3.2	3.5	1.6	3.6	3.3	-3.1	-3.1	-3.4	-3.7	-3.3	-3.4	-3.6	3.2	-4.0	-3.3	3.7
Neuroticism	0.1	0.4	1.4	-1.0	-0.5	0.5	1.2	0.7	0.7	-0.1	-0.1	-0.4	-0.5	-0.4	-0.4	-0.5	0.8	-0.2	-0.3	0.6
Chronotype (morning person)	0.0	0.1	1.2	0.1	0.1	-0.1	1.1	0.1	-0.0	0.4	-0.1	0.2	-0.2	0.1	0.0	0.3	0.1	-0.2	0.4	-0.2
Hair Pigment	0.1	1.8	3.6	-0.5	-0.8	1.6	-0.2	0.8	1.3	-1.9	0.2	-1.7	-1.0	-1.7	-1.4	-1.8	1.0	-1.6	-1.9	1.5
Tanning	0.0	0.5	1.4	-0.7	-1.2	0.7	-1.2	0.7	0.5	-0.9	-0.8	-0.9	-0.4	-0.5	-0.3	-0.7	0.7	-0.2	-0.9	0.5
Hand grip strength (left)	0.0	0.1	0.5	0.4	0.4	-0.1	-0.2	0.7	0.2	0.1	0.2	0.3	0.4	0.1	-0.0	0.2	0.2	0.1	0.2	0.1
Number of treatments/medications taken	1.7	3.0	6.6	-2.0	-1.6	1.8	1.6	2.6	2.0	-1.1	-1.9	-1.3	-1.8	-1.3	-1.6	-1.5	2.2	-1.4	-1.2	1.9
Average weekly spirits intake	0.2	0.3	1.0	0.1	0.3	-0.6	0.5	-0.0	-0.0	1.0	-0.3	0.9	0.2	0.6	0.3	0.7	-0.0	0.7	1.0	-0.2
Sensitivity / hurt feelings	0.8	1.5	3.1	1.0	1.0	-1.2	-0.9	-1.1	-1.1	1.8	1.0	1.2	1.1	1.4	1.3	1.3	-0.8	1.0	1.6	-1.3
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.7	0.2	0.4	0.0	0.6	0.5	0.4	0.8	0.1	0.2	-0.0	-0.2	-0.4	0.3	0.4	-0.0	0.8	0.2
Hearing difficulty/problems: Yes	0.3	0.4	0.6	-0.6	-0.6	0.7	-0.2	0.7	0.7	-0.6	-0.6	-0.7	-0.6	-0.6	-0.7	-0.7	0.8	-0.5	-0.6	0.7
Relative age of first facial hair	0.2	0.3	0.7	0.2	-0.4	0.6	0.5	0.8	0.6	-0.6	-0.5	-0.4	-0.7	-0.6	-0.7	-0.5	0.5	-0.8	-0.5	0.6
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	3.5	-1.1	-1.2	0.9	1.9	1.1	0.8	-1.0	-0.8	-1.1	-1.1	-0.8	-0.7	-0.9	0.8	-0.7	-1.0	0.9
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.5	-0.4	0.1	-0.3	-0.6	0.5	-0.0	0.6	-0.0	0.4	0.4	0.6	0.5	0.5	0.3	0.7	0.6	-0.3
Ever had hysterectomy (womb removed)	2.8	3.2	4.9	2.1	2.0	-1.9	-0.3	-2.2	-1.9	1.7	2.1	1.7	1.7	1.6	1.6	1.7	-2.0	1.3	1.7	-1.9
Systolic blood pressure, automated reading	0.0	0.1	0.9	-0.8	0.2	-0.1	-0.2	-0.1	0.2	0.3	-0.2	0.2	0.4	-0.0	-0.2	0.2	0.1	0.9	0.3	-0.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.2	-0.5	-0.7	0.9	-0.5	0.4	0.4	-0.7	-0.2	-0.8	-0.8	-0.7	-0.4	-0.7	0.3	-1.1	-0.8	0.6
Angina	0.2	0.2	0.7	-0.5	0.0	-0.3	-0.8	-0.3	-0.5	-0.4	0.7	0.0	0.5	0.4	0.7	0.1	-0.4	0.8	-0.3	-0.3
Medication for hormone replacement therapy	0.6	0.7	2.5	-0.7	-0.8	0.8	0.8	1.6	1.0	-0.6	-0.8	-0.5	-0.8	-0.6	-0.8	-0.7	0.9	-0.9	-0.6	0.9
Vitamin and mineral supplements	0.4	0.6	1.6	-0.2	-0.8	0.9	-0.2	0.6	0.6	-0.8	-0.5	-1.1	-0.9	-0.8	-0.5	-0.8	0.5	-1.3	-0.8	0.8
Supplements: Zinc	0.1	0.1	0.8	-0.2	-0.2	0.1	0.9	0.6	0.4	0.0	-0.7	0.1	-0.3	-0.1	-0.4	-0.1	0.4	-0.1	0.0	0.3
Medication: Co-codamol	2.9	3.3	4.7	-2.0	-1.9	2.0	2.1	1.7	1.9	-1.3	-1.8	-1.7	-2.2	-1.6	-1.6	-1.6	2.1	-1.9	-1.4	1.9
Medication: Metformin	0.7	1.0	2.4	1.2	0.8	-0.7	-0.8	-0.9	-1.1	0.6	1.3	0.7	1.1	1.2	1.5	1.1	-0.7	0.6	0.8	-1.1
Diabetes (father)	1.1	1.4	3.0	-1.7	-1.6	1.2	0.7	1.0	0.8	-1.5	-1.1	-1.4	-1.2	-1.2	-1.0	-1.3	0.5	-0.7	-1.4	1.3
Diabetes (mother)	0.5	0.7	2.9	-1.1	-1.0	0.7	1.7	0.8	0.6	-0.5	-1.2	-0.7	-0.8	-0.3	-0.1	-0.5	0.9	-0.3	-0.6	0.6
Severe depression (siblings)	0.1	0.1	0.8	0.9	0.5	-0.3	0.1	-0.3	0.1	0.3	0.3	0.7	-0.0	0.3	-0.1	0.2	0.2	-0.2	0.4	0.1
Pack years adult smoking proportion	3.0	4.6	8.7	2.9	2.9	-2.2	-0.3	-2.0	-1.7	2.6	2.7	2.5	1.8	2.1	1.7	2.2	-1.6	0.8	2.6	-1.9
Impedance of leg (right)	1.3	6.4	9.7	-1.9	-2.8	2.6	2.8	2.6	2.3	-3.1	-2.3	-2.8	-2.5	-2.6	-2.1	-2.6	2.2	-2.0	-2.9	2.4
Leg fat-free mass (left)	0.0	0.1	0.6	-0.2	0.2	-0.4	-0.7	-0.1	-0.1	0.7	-0.0	0.4	0.3	0.5	0.3	0.3	0.1	0.3	0.5	-0.1
Trunk fat percentage	0.3	1.1	3.3	-1.3	-1.4	0.9	-0.7	1.0	1.0	-0.6	-1.8	-1.0	-1.1	-0.9	-0.9	-0.9	1.1	-0.7	-0.7	1.0
Hand grip strength (right)	0.0	0.1	0.2	0.2	0.5	0.0	-0.0	0.5	0.3	0.1	0.3	0.3	0.2	0.2	-0.2	0.0	0.3	-0.0	0.1	0.2
Townsend deprivation index at recruitment	0.1	0.1	0.6	0.1	-0.2	-0.0	0.7	-0.3	-0.2	0.6	-0.0	-0.0	0.3	0.1	0.4	0.3	-0.3	0.6	0.4	-0.1
Current tobacco smoking	1.2	1.9	2.8	1.3	1.5	-1.7	-0.6	-1.3	-1.6	1.2	1.3	1.5	1.3	1.6	1.4	1.2	-1.5	1.4	1.2	-1.4
Average weekly fortified wine intake	0.1	0.1	0.4	-0.5	-0.6	0.6	0.4	0.2	0.2	-0.1	-0.4	-0.6	-0.4	-0.4	-0.2	-0.2	0.2	-0.3	-0.1	0.2
Maternal smoking around birth	4.6	6.7	10.3	-3.2	-3.0	2.7	0.6	2.6	2.5	-2.6	-2.9	-3.0	-2.6	-2.9	-2.6	-2.7	2.3	-1.6	-2.7	2.5
Fed-up feelings	1.2	2.1	4.9	1.3	1.9	-1.6	0.2	-1.4	-1.2	1.5	2.2	1.7	1.5	1.6	1.3	1.4	-1.0	1.3	1.5	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.8	0.7	0.6	-0.5	0.5	-0.3	-0.0	0.9	0.7	0.5	0.4	0.2	0.5	0.8	0.0	0.3	0.8	-0.4
Relative age voice broke	2.1	3.2	6.5	-1.0	-1.5	2.0	1.6	1.9	1.6	-1.8	-1.2	-1.8	-2.1	-1.9	-2.1	-1.9	1.4	-2.6	-1.7	1.9
Taking other prescription medications	1.2	1.8	3.8	-1.4	-1.4	1.5	1.8	1.9	1.4	-0.8	-1.2	-1.3	-1.5	-1.1	-1.0	-1.1	1.5	-1.1	-1.0	1.4
Age when periods started (menarche)	1.8	4.3	8.3	-2.0	-2.7	2.6	0.3	1.8	1.8	-2.1	-2.1	-2.9	-2.0	-2.4	-1.6	-2.1	1.5	-1.6	-2.2	2.0
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.4	-0.2	-0.5	0.4	-0.0	0.6	0.6	-0.5	-0.2	-0.5	-0.4	-0.6	-0.4	-0.5	0.6	-0.6	-0.6	0.5
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.6	4.0	-1.5	-1.5	1.7	2.0	1.4	1.6	-1.8	-1.4	-1.5	-1.7	-1.6	-1.7	-1.7	1.6	-1.4	-1.7	1.7
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.6	-0.1	-0.1	0.5	-0.8	0.2	0.2	-0.4	-0.2	-0.1	-0.1	0.1	-0.1	-0.3	0.4	0.1	-0.3	0.4
Qualifications: CSEs or equivalent	2.4	3.2	8.0	-1.4	-1.7	1.9	2.8	1.4	1.8	-1.5	-1.5	-1.8	-1.7	-2.0	-1.9	-1.7	1.7	-1.4	-1.6	1.7
Serious illness, injury or assault to yourself	0.2	0.2	0.9	0.1	-0.1	-0.4	-0.9	-0.6	-0.5	0.1	0.2	-0.0	0.5	0.2	0.7	0.4	-0.3	0.9	0.2	-0.6
High blood pressure	0.1	0.2	0.4	-0.7	-0.3	0.4	0.4	0.4	0.4	-0.1	-0.2	-0.4	-0.5	-0.4	-0.4	-0.4	0.4	-0.4	-0.2	0.4
Hayfever, allergic rhinitis or eczema	2.0	4.3	6.5	-1.2	-2.5	2.2	0.6	2.5	2.0	-1.9	-2.5	-2.1	-2.3	-2.3	-2.2	-2.2	1.5	-2.1	-2.0	2.2
Multivitamins +/- minerals	0.3	0.4	3.1	-0.8	-0.3	0.4	1.8	0.6	0.7	-0.3	-0.6	0.1	-0.2	-0.2	-0.6	-0.4	0.8	0.2	-0.3	0.5
Stomach or abdominal pain in last month	6.1	7.6	10.1	-1.8	-2.8	3.1	2.1	2.5	2.7	-2.9	-2.2	-3.1	-3.0	-3.0	-2.7	-3.0	2.6	-3.2	-3.0	2.9
Supplements: Glucosamine	0.1	0.1	0.5	-0.7	0.1	-0.3	0.5	-0.1	0.0	0.0	-0.2	0.3	-0.1	0.1	-0.3	-0.1	-0.1	0.4	0.0	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.4	0.6	0.6	-0.6	0.0	-0.1	-0.3	0.4	0.6	0.4	0.2	0.3	0.1	0.4	-0.2	-0.4	0.5	-0.5
Medication: Atenolol	0.3	0.4	1.0	-0.8	-1.0	0.7	-0.1	0.3	0.4	-0.8	-0.6	-1.0	-0.4	-0.7	-0.3	-0.4	0.6	0.1	-0.6	0.3
Medication: Levothyroxine sodium	0.2	0.3	3.3	0.2	0.5	-0.3	1.8	0.3	-0.0	0.6	0.1	0.5	0.2	0.4	0.2	0.5	0.1	0.4	0.6	-0.2
Sitting height	0.3	2.0	3.4	-1.7	-1.4	1.2	0.9	1.8	1.3	-1.8	-1.2	-1.5	-1.1	-1.1	-0.9	-1.6	1.4	-0.8	-1.8	1.5
Chronic bronchitis/emphysema (father)	0.1	0.1	0.3	-0.4	-0.5	0.2	-0.1	0.2	0.3	-0.2	-0.4	-0.4	-0.4	-0.5	-0.3	-0.2	0.4	0.0	-0.1	0.2
High blood pressure (mother)	2.3	3.3	7.6	-2.5	-2.3	1.9	2.8	1.5	1.6	-1.5	-2.1	-1.9	-1.6	-1.8	-1.4	-1.6	1.5	-0.5	-1.6	1.5
Body mass index (BMI)	0.4	1.6	3.0	0.8	1.2	-1.4	-1.1	-1.3	-1.1	1.7	0.7	1.4	1.1	1.4	1.1	1.4	-0.9	1.2	1.6	-1.2
Impedance of leg (left)	2.0	9.6	15.1	-2.6	-3.4	3.2	2.8	3.1	2.9	-3.9	-2.9	-3.4	-3.0	-3.2	-2.8	-3.2	2.8	-2.4	-3.6	3.0
Leg predicted mass (left)	0.0	0.1	0.4	-0.3	0.2	-0.3	-0.6	-0.0	-0.0	0.7	-0.1	0.3	0.2	0.4	0.2	0.2	0.1	0.3	0.5	-0.0
Trunk fat mass	0.1	0.5	1.8	-1.1	-1.0	0.6	-0.7	0.7	0.7	-0.2	-1.3	-0.6	-0.7	-0.5	-0.5	-0.5	0.8	-0.4	-0.3	0.7
Waist circumference	0.5	1.7	2.9	0.8	1.2	-1.5	-1.4	-1.2	-1.1	1.7	0.8	1.5	1.2	1.3	1.1	1.4	-1.0	1.4	1.6	-1.2
Number of incorrect matches in round	0.9	1.5	2.7	1.2	1.5	-1.0	-1.1	-1.5	-1.3	1.0	1.6	1.2	1.3	1.3	1.2	0.9	-1.3	0.5	1.0	-1.1
Past tobacco smoking	0.7	1.3	2.5	-1.6	-0.8	1.4	1.2	0.9	1.2	-0.7	-1.3	-0.8	-1.4	-1.0	-1.3	-1.0	1.2	-1.3	-0.7	1.2
Alcohol usually taken with meals	1.3	2.1	3.5	1.0	1.3	-1.2	-1.2	-0.9	-1.7	1.9	1.3	1.1	1.5	1.4	1.7	1.6	-1.8	1.3	1.7	-1.6
Nervous feelings	1.6	3.0	4.7	-1.8	-2.0	1.7	1.8	1.7	1.7	-1.4	-2.1	-1.7	-2.2	-1.8	-1.7	-1.5	1.6	-1.8	-1.4	1.6
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.1	-1.1	-0.8	0.8	1.4	1.1	1.1	-0.3	-1.2	-0.6	-0.9	-0.6	-0.7	-0.6	1.3	-0.3	-0.4	0.9
Hearing difficulty/problems with background noise	0.3	0.5	1.4	-0.7	-0.8	0.8	0.1	0.8	0.7	-0.6	-1.2	-0.7	-0.6	-0.7	-0.6	-0.7	0.8	-0.2	-0.7	0.7
Hair/balding pattern: Pattern 2	0.0	0.1	0.2	0.0	-0.0	-0.2	0.0	-0.2	-0.3	0.0	0.4	0.1	0.2	0.3	0.5	0.1	-0.4	0.1	-0.0	-0.2
Had menopause	1.7	2.1	4.8	0.1	0.8	-1.7	-1.3	-1.1	-1.5	1.9	0.2	1.3	1.4	1.4	1.4	1.7	-1.3	2.2	1.9	-1.6
Had other major operations	0.2	0.2	0.4	-0.3	-0.6	0.3	-0.6	0.5	0.3	-0.0	-0.6	-0.5	-0.7	-0.6	-0.5	-0.3	0.0	-0.5	-0.2	0.4
Forced vital capacity (FVC)	1.6	6.0	8.6	-1.4	-2.2	2.6	1.9	2.9	2.5	-2.5	-2.2	-2.4	-2.5	-2.2	-2.5	-2.6	2.6	-2.9	-2.5	2.8
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.0	6.4	-1.7	-2.1	2.0	2.4	1.6	1.7	-2.5	-1.8	-2.1	-2.1	-2.0	-1.9	-2.2	1.8	-1.8	-2.4	1.9
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.9	-0.1	0.0	-0.7	-0.7	-0.8	-1.0	0.7	-0.2	0.5	0.7	0.7	1.1	0.8	-1.0	1.7	0.7	-0.9
Qualifications: None of the above	0.1	0.1	0.5	0.4	0.6	-0.3	0.7	-0.4	-0.1	0.3	0.4	0.4	-0.1	0.1	-0.3	0.2	-0.0	-0.6	0.4	-0.2
Financial difficulties in last 2 years	0.5	0.7	1.9	0.7	0.6	-0.7	0.7	-1.3	-1.1	0.1	1.4	0.5	0.9	0.7	0.9	0.5	-0.9	1.0	0.2	-0.9
Mouth/teeth dental problems	0.6	1.0	3.7	1.0	0.8	-1.1	-1.9	-0.4	-0.6	1.1	0.3	1.2	0.9	1.0	0.6	1.0	-0.5	0.9	1.2	-0.8
Heart attack	0.6	0.8	5.5	0.3	0.3	-0.7	-2.3	-0.3	-0.7	0.5	0.0	0.6	1.0	0.8	1.0	0.8	-0.6	1.3	0.6	-0.8
Allergy	2.2	5.1	7.0	1.7	2.6	-2.3	-2.0	-2.6	-2.2	1.7	2.6	2.3	2.4	2.6	2.4	2.2	-1.8	2.1	1.9	-2.3
Pain all over the body in last month	5.8	6.2	8.6	-2.5	-2.5	2.7	0.3	2.7	2.4	-2.4	-2.3	-2.9	-2.5	-2.9	-2.8	-2.8	2.1	-2.3	-2.6	2.6
Diabetes (self-reported)	1.4	2.2	3.2	1.6	1.3	-1.5	-1.5	-1.4	-1.5	1.4	1.3	1.5	1.4	1.8	1.8	1.6	-1.2	1.1	1.5	-1.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.1	-0.2	-1.0	0.7	0.5	0.5	0.4	-0.9	-0.5	-0.8	-0.9	-0.8	-0.5	-0.7	0.2	-1.0	-0.8	0.5
Medication: Ramipril	0.2	0.2	0.6	-0.7	-0.7	0.5	0.1	0.5	0.4	-0.4	-0.6	-0.4	-0.3	-0.1	0.1	-0.2	0.8	0.1	-0.4	0.4
Medication: Simvastatin	0.0	0.0	0.2	0.4	-0.2	0.1	0.4	0.0	0.1	0.0	0.1	-0.3	0.1	-0.1	0.2	0.0	0.4	-0.2	-0.1	-0.1
Fluid intelligence score	0.9	1.8	3.5	-1.7	-1.6	1.4	-0.2	1.7	1.2	-1.4	-1.9	-1.3	-1.2	-1.2	-1.2	-1.4	1.1	-0.5	-1.4	1.4
Illnesses of siblings	0.8	1.1	5.9	1.4	1.2	-1.1	-2.4	-0.7	-0.8	0.7	1.1	1.1	0.9	1.0	0.7	0.8	-0.7	0.2	0.8	-0.8
Neuroticism score	0.0	0.0	0.3	-0.1	0.1	-0.1	0.6	-0.1	-0.0	0.2	0.4	0.1	-0.1	0.1	0.1	0.1	0.1	-0.1	0.2	-0.1
Weight	0.0	0.1	0.6	-0.3	0.1	-0.4	-0.3	-0.1	-0.1	0.7	-0.2	0.4	0.2	0.5	0.3	0.4	0.1	0.5	0.6	-0.1
Impedance of arm (right)	0.9	4.2	6.4	-1.8	-2.5	2.3	-0.1	2.0	1.9	-2.2	-2.5	-2.5	-1.9	-2.3	-2.0	-2.2	1.8	-1.6	-2.3	2.0
Arm fat percentage (right)	0.1	0.3	1.5	0.0	-0.0	-0.4	-1.2	-0.5	-0.4	0.9	-0.3	0.3	0.3	0.4	0.4	0.5	-0.3	0.5	0.7	-0.4
Trunk fat-free mass	0.1	0.6	1.3	0.2	0.7	-0.8	0.3	-0.5	-0.7	1.0	0.7	0.8	0.8	1.2	1.1	0.8	-0.4	0.8	0.9	-0.6
Hip circumference	0.1	0.4	1.0	-0.5	-0.7	0.5	-0.4	0.3	0.5	-0.3	-1.0	-0.6	-0.8	-0.6	-0.7	-0.5	0.5	-0.9	-0.3	0.6
Time employed in main current job	3.6	4.2	7.0	-2.2	-2.4	2.0	0.3	1.6	1.6	-2.3	-2.0	-2.6	-2.3	-2.4	-2.0	-2.3	1.4	-2.0	-2.4	1.9
Alcohol intake versus 10 years previously	0.4	0.6	1.7	-1.0	-1.0	0.8	0.1	1.3	0.7	-0.8	-1.1	-0.8	-0.7	-0.3	-0.3	-0.7	1.0	-0.5	-0.7	0.8
Father’s age at death	0.3	0.4	0.9	0.5	0.8	-0.6	0.1	-0.4	-0.6	1.0	0.5	0.8	0.6	0.7	0.6	0.8	-0.5	0.5	0.9	-0.7
Worrier / anxious feelings	0.5	0.9	2.1	0.3	0.7	-0.8	-0.0	0.1	-0.9	1.3	0.7	1.0	0.9	1.4	1.4	1.1	-0.5	1.0	1.2	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.4	0.0	-0.0	0.3	0.8	0.9	0.9	-0.5	0.2	-0.1	-0.1	-0.2	-0.3	-0.3	1.2	-0.4	-0.4	0.5
Falls in the last year	2.1	2.9	5.1	1.1	1.6	-1.8	-0.8	-1.8	-1.7	1.9	1.9	1.5	2.0	1.5	1.6	1.7	-1.6	2.3	1.8	-1.8
Hair/balding pattern: Pattern 3	2.5	3.8	5.7	1.8	2.4	-2.2	-0.9	-2.0	-1.7	2.3	1.4	2.3	1.9	2.0	1.6	2.1	-1.7	1.9	2.3	-1.9
Number of live births	1.1	1.6	4.7	-1.0	-1.0	1.5	2.2	0.8	1.1	-1.5	-0.7	-1.4	-1.2	-1.4	-1.3	-1.3	0.8	-1.2	-1.3	1.2
Forced expiratory volume in 1-second (FEV1)	1.5	5.0	6.6	-1.4	-2.1	2.4	1.8	2.6	2.3	-2.3	-2.1	-2.2	-2.3	-2.1	-2.2	-2.3	2.4	-2.5	-2.3	2.4
Pulse rate	0.2	0.3	1.2	-0.5	0.5	0.2	0.2	1.1	0.8	0.4	-0.5	0.7	-0.1	0.3	-0.4	0.1	0.9	0.1	0.4	0.5
Happiness	0.5	0.6	3.2	-0.3	0.1	-0.6	-1.3	0.1	-0.3	0.7	-0.3	0.7	0.9	0.9	1.0	0.8	0.0	1.8	0.7	-0.5
Noisy workplace	1.6	1.9	3.1	-1.1	-1.0	1.3	1.8	1.2	1.7	-1.4	-1.1	-1.0	-1.6	-1.3	-1.6	-1.4	1.8	-1.4	-1.3	1.6
Qualifications: A levels/AS levels or equivalent	0.7	1.7	8.7	1.3	0.8	-0.9	-3.0	-1.4	-1.6	0.3	1.4	0.5	1.1	0.9	1.2	0.6	-2.0	0.7	0.3	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.6	-0.2	-0.5	0.6	0.8	0.6	0.5	-0.6	-0.3	-0.5	-0.5	-0.3	-0.3	-0.4	0.7	-0.8	-0.5	0.4
Mouth/teeth dental problems: Dentures	0.4	0.7	1.6	-1.0	-0.6	1.0	1.2	0.8	0.7	-0.5	-0.6	-1.0	-0.8	-0.7	-0.6	-0.8	0.7	-1.0	-0.7	0.9
Asthma	0.3	0.7	1.3	-1.1	-1.1	0.7	1.0	1.2	0.8	-0.3	-1.0	-0.8	-0.6	-1.1	-0.8	-0.5	0.5	0.0	-0.5	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.6	0.0	0.3	-0.3	-0.8	-0.1	-0.3	0.6	-0.2	0.5	0.5	0.4	0.3	0.6	-0.3	0.8	0.7	-0.4
Medication: Cholesterol lowering	0.5	0.7	1.7	-0.6	-1.1	0.9	0.8	0.9	0.6	-0.9	-0.5	-1.3	-0.8	-0.8	-0.3	-0.9	0.8	-0.9	-1.1	0.8
Depression (self-reported)	0.5	0.6	1.7	0.1	0.8	-1.0	0.1	-0.4	-0.4	1.2	0.5	1.1	0.9	1.0	0.7	0.8	-0.1	1.3	1.0	-0.5
Medication: Lansoprazole	0.5	0.6	1.2	-0.8	-0.8	0.8	0.6	0.9	0.9	-0.4	-0.9	-0.8	-0.9	-0.7	-0.8	-0.6	1.1	-0.9	-0.4	0.7
Prospective memory result	0.5	0.6	4.1	-0.9	-0.5	0.8	2.0	0.4	0.6	-0.6	-0.3	-0.9	-0.7	-0.9	-0.6	-0.4	0.8	-0.4	-0.5	0.3
Lung cancer (father)	3.3	3.9	6.3	-2.5	-2.1	2.3	1.6	1.4	2.0	-1.7	-2.0	-2.1	-2.0	-2.2	-2.2	-2.0	1.8	-1.5	-1.8	2.1
Illnesses of mother	1.9	2.4	4.9	2.2	2.1	-1.6	-2.2	-1.5	-1.4	1.2	2.0	1.6	1.3	1.4	1.0	1.3	-1.4	0.1	1.4	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.2	7.1	9.0	-2.1	-2.8	2.8	1.6	3.0	2.7	-2.6	-2.9	-2.8	-2.8	-2.7	-2.7	-2.8	2.5	-2.6	-2.7	2.9
Pulse wave Arterial Stiffness index	1.5	1.8	3.8	-1.5	-1.1	1.1	1.6	1.9	1.6	-1.0	-1.6	-0.9	-1.3	-0.9	-1.0	-1.0	1.9	-0.9	-0.9	1.3
Impedance of arm (left)	1.0	4.7	6.4	-1.6	-2.5	2.4	-0.2	2.1	2.0	-2.4	-2.5	-2.5	-2.1	-2.5	-2.3	-2.3	1.9	-2.0	-2.4	2.1
Arm fat mass (right)	0.0	0.1	0.5	-0.2	-0.2	-0.2	-0.3	-0.3	-0.1	0.7	-0.4	0.2	0.0	0.2	0.2	0.3	-0.0	0.3	0.5	-0.2
Trunk predicted mass	0.1	0.7	1.5	0.3	0.8	-0.9	0.2	-0.6	-0.7	1.1	0.8	0.9	0.9	1.2	1.1	0.9	-0.4	0.9	1.0	-0.7
Standing height	0.5	5.1	7.5	-2.5	-2.4	2.2	2.1	2.7	2.3	-2.3	-2.2	-2.4	-2.1	-2.0	-1.9	-2.3	2.4	-1.7	-2.3	2.4
Length of working week for main job	0.4	0.4	1.1	1.1	0.6	-0.7	-0.5	-0.4	-0.6	0.4	0.6	0.6	0.8	0.7	0.9	0.7	-0.3	0.6	0.5	-0.8
Exposure to tobacco smoke at home	2.5	2.8	3.8	-1.6	-1.9	1.5	1.5	1.2	1.7	-1.7	-1.9	-1.5	-1.7	-1.7	-1.8	-1.7	1.7	-1.5	-1.7	1.7
Breastfed as a baby	1.3	1.7	2.7	0.4	0.9	-1.1	-1.4	-1.6	-1.5	1.3	1.2	0.8	1.4	1.3	1.6	1.2	-1.5	1.5	1.1	-1.3
Tense / ‘highly strung’	2.3	3.9	4.6	-2.0	-2.1	2.1	1.6	1.7	1.9	-2.1	-1.8	-2.0	-2.1	-2.0	-1.9	-2.0	2.0	-2.0	-2.1	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.4	0.2	0.3	-0.1	0.3	0.1	0.1	0.6	0.1	0.3	0.4	0.3	0.1	0.3	0.4	0.4	0.4	-0.0
Hair/balding pattern: Pattern 4	3.4	8.3	13.9	-3.1	-3.3	2.7	0.9	2.2	2.7	-3.7	-2.6	-3.1	-2.9	-2.9	-2.6	-3.3	2.5	-2.4	-3.7	2.9
Birth weight of first child	1.6	3.0	4.0	1.8	1.8	-2.0	-1.6	-1.5	-1.7	2.0	1.5	1.8	1.6	1.7	1.5	1.8	-1.7	1.4	2.0	-1.7
Peak expiratory flow (PEF)	2.0	4.6	6.1	-1.5	-2.2	2.5	0.3	2.3	2.2	-2.2	-2.3	-2.2	-2.2	-2.2	-2.2	-2.2	2.2	-2.4	-2.1	2.4
Pulse wave reflection index	0.1	0.1	0.8	-0.1	-0.4	-0.1	0.9	-0.1	-0.3	-0.3	-0.0	-0.1	-0.1	0.2	0.5	0.0	0.0	0.3	-0.2	-0.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.9	-0.4	-0.3	0.5	1.4	0.7	0.6	-0.4	-0.3	-0.3	-0.3	-0.2	-0.3	-0.4	0.8	-0.1	-0.4	0.5
Loud music exposure frequency	4.2	4.6	7.2	-2.7	-2.2	1.9	2.3	2.0	2.5	-2.0	-2.5	-1.8	-1.9	-1.9	-1.9	-2.1	2.4	-0.9	-2.1	2.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.0	1.1	0.6	-1.3	-1.2	-1.5	-1.6	0.7	1.2	0.6	1.1	1.0	1.6	0.9	-1.7	1.3	0.7	-1.2
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	4.4	1.2	1.2	-1.3	0.3	-2.1	-1.6	0.9	1.5	1.1	1.2	1.2	1.2	1.2	-1.8	1.0	1.1	-1.5
Blood clot in the leg (DVT)	0.1	0.1	1.2	-0.0	0.0	-0.0	1.1	-0.2	-0.3	0.3	0.6	-0.3	-0.0	-0.2	0.1	0.1	-0.4	-0.1	0.2	-0.2
Medication: Paracetamol	4.8	8.0	10.1	-2.7	-2.6	3.1	3.0	2.9	3.1	-2.3	-2.8	-2.6	-3.1	-2.8	-3.1	-2.7	3.2	-2.8	-2.4	3.0
Headache pain in last month	2.8	4.9	6.5	-1.8	-2.0	2.2	2.1	2.5	2.5	-2.2	-2.1	-2.1	-2.4	-2.2	-2.2	-2.2	2.5	-2.0	-2.1	2.3
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.3	0.1	0.2	-0.2	0.1	0.1	0.1	0.0	-0.2	0.4	0.2	0.1	-0.1	0.2	-0.0	0.5	0.2	-0.1
Glaucoma (self-reported)	0.1	0.1	1.3	0.5	-0.0	-0.1	-1.1	0.0	0.0	0.0	-0.1	0.0	-0.2	-0.2	-0.2	-0.1	-0.2	-0.4	-0.0	0.1
Gout (self-reported)	1.1	1.5	3.8	2.0	1.5	-1.3	0.4	-1.2	-1.0	1.1	1.7	1.3	1.1	1.1	0.9	1.2	-0.9	0.6	1.2	-1.1
Hypothyroidism/myxoedema (self-reported)	0.5	1.1	1.7	1.0	0.9	-1.0	0.9	-0.4	-0.9	1.2	0.8	1.0	1.1	1.1	1.3	1.3	-0.6	1.3	1.2	-1.1
Medication: Amlodipine	0.4	0.5	2.2	-0.5	0.5	-0.9	-0.5	-0.2	-0.4	0.9	0.0	0.9	0.9	0.7	0.6	0.7	-0.3	1.5	0.8	-0.6
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.9	-0.4	-0.7	0.9	0.8	0.5	0.6	-0.7	-0.6	-0.8	-0.8	-1.0	-0.9	-0.8	0.3	-0.6	-0.7	0.7
Birth weight	3.6	7.8	12.8	2.7	3.3	-3.1	0.2	-2.9	-2.9	2.7	3.6	2.8	3.0	2.8	2.8	2.6	-2.9	2.4	2.6	-2.8
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.9	-0.8	-0.9	0.7	-0.7	0.2	0.1	-0.5	-0.9	-0.7	-0.6	-0.4	-0.4	-0.6	0.0	-0.3	-0.5	0.4
High blood pressure (siblings)	0.1	0.1	0.4	-0.1	-0.5	0.2	0.6	-0.6	-0.3	-0.3	-0.1	-0.5	0.1	-0.4	0.1	-0.1	-0.5	0.5	-0.3	-0.2
Forced vital capacity (FVC), Best measure	2.5	9.1	11.6	-2.3	-3.1	3.1	1.6	3.4	3.0	-3.0	-3.2	-3.1	-3.2	-3.0	-3.1	-3.2	2.8	-3.1	-3.1	3.3
Body fat percentage	0.2	0.7	2.1	-1.2	-1.2	0.8	-0.5	0.8	0.8	-0.4	-1.5	-0.8	-0.9	-0.7	-0.7	-0.7	0.9	-0.5	-0.5	0.8
Leg fat percentage (right)	0.1	0.2	0.6	-0.7	-0.6	0.4	0.5	0.5	0.4	-0.0	-0.8	-0.3	-0.5	-0.2	-0.2	-0.2	0.7	-0.1	-0.0	0.4
Arm fat-free mass (right)	0.0	0.1	0.3	-0.3	0.2	-0.4	0.6	-0.1	-0.2	0.4	0.2	0.3	0.2	0.5	0.4	0.3	-0.0	0.3	0.4	-0.1
Exposure to tobacco smoke outside home	0.4	0.5	2.0	0.6	0.7	-0.6	1.4	-0.6	-0.2	0.8	0.3	0.9	0.6	0.9	0.7	0.8	0.1	0.7	0.8	-0.5
Comparative body size at age 10	6.4	17.7	20.4	4.4	4.5	-4.3	-2.6	-4.5	-4.2	4.5	4.2	4.5	4.3	4.3	3.9	4.3	-4.1	3.6	4.5	-4.4
Number of full brothers	0.1	0.1	0.4	0.6	0.2	-0.0	0.1	-0.5	-0.3	-0.1	0.4	-0.0	-0.0	0.1	0.1	-0.0	-0.2	-0.3	-0.1	-0.1
Worry too long after embarrassment	0.1	0.1	0.3	-0.3	-0.4	0.6	0.5	0.5	0.3	-0.3	-0.0	-0.6	-0.3	-0.3	-0.1	-0.4	0.2	-0.3	-0.4	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.5	-1.0	-0.7	0.9	0.2	1.2	0.9	-0.6	-1.2	-0.7	-0.8	-0.5	-0.6	-0.7	1.2	-0.3	-0.6	0.9
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	-0.5	-0.3	0.5	0.7	0.6	0.6	-0.2	-0.4	-0.4	-0.3	-0.7	-0.7	-0.3	0.4	0.1	-0.2	0.4
Number of children fathered	0.6	0.7	3.8	-0.7	-0.5	0.7	1.9	1.3	1.0	-0.3	-0.5	-0.2	-0.8	-0.3	-0.5	-0.5	1.1	-0.6	-0.4	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.6	0.9	1.0	-0.8	0.8	-0.6	-0.2	1.3	0.2	1.1	0.6	0.6	0.2	0.9	-0.1	0.3	1.2	-0.5
Age at first live birth	0.7	1.3	13.2	1.1	0.9	-0.8	-3.6	-0.8	-0.6	0.9	0.6	0.6	0.9	0.5	0.5	0.5	-0.8	0.3	0.7	-0.4
Pulse wave peak to peak time	0.9	1.1	2.8	1.3	0.8	-0.8	-1.5	-1.7	-1.3	0.6	1.3	0.5	1.0	0.5	0.8	0.7	-1.6	0.6	0.6	-1.0
Health satisfaction	0.2	0.3	1.0	-0.1	0.6	-0.3	-0.4	-0.0	-0.1	0.4	0.6	0.7	0.7	0.7	0.6	0.4	0.0	1.0	0.3	-0.2
Shortness of breath walking on level ground	1.3	1.5	2.7	1.3	1.6	-1.2	-1.3	-0.9	-0.9	1.5	1.2	1.5	1.1	1.2	0.9	1.4	-1.1	0.8	1.6	-1.1
Qualifications: College or University degree	0.5	1.7	2.6	1.6	1.5	-1.2	-1.1	-0.7	-1.3	1.4	1.4	1.2	1.6	1.1	1.3	1.4	-1.3	1.3	1.4	-1.3
Eye problems/disorders: None of the above	0.3	0.3	2.6	-0.6	0.1	-0.4	0.8	-0.6	-0.3	0.3	0.0	0.1	0.8	0.1	0.5	0.4	-0.3	1.6	0.1	-0.5
Mouth/teeth dental problems: Loose teeth	2.2	2.6	4.2	-1.7	-1.3	1.7	1.2	1.5	1.8	-1.5	-1.7	-1.4	-1.7	-1.8	-2.0	-1.7	1.6	-1.5	-1.5	1.7
Emphysema/chronic bronchitis	1.6	1.9	4.7	1.7	2.2	-1.3	-0.4	-1.0	-0.9	1.7	1.8	1.7	1.4	1.3	0.7	1.3	-0.9	0.9	1.6	-1.1
Medication for pain relief, constipation, heartburn	4.2	7.1	9.9	2.5	2.8	-3.0	-1.1	-3.0	-2.9	2.5	2.8	2.6	2.8	2.4	2.5	2.6	-3.1	2.6	2.4	-2.9
Neck or shoulder pain in last month	3.1	4.5	5.7	-1.8	-2.2	2.2	2.3	1.9	2.0	-2.1	-1.5	-2.3	-2.4	-2.3	-2.1	-2.1	2.0	-2.3	-2.1	2.1
Medication: Blood pressure	0.0	0.1	0.7	-0.2	0.1	-0.0	-0.8	-0.2	-0.2	0.2	0.3	-0.2	-0.1	0.2	0.2	-0.1	-0.3	-0.4	0.0	0.0
Angina (self-reported)	0.2	0.2	0.6	-0.4	-0.0	-0.3	-0.8	-0.4	-0.6	-0.5	0.7	-0.1	0.4	0.3	0.7	0.1	-0.4	0.7	-0.3	-0.4
Migraine (self-reported)	2.2	2.8	6.7	-1.6	-1.6	1.7	2.6	1.9	1.8	-1.0	-1.7	-1.5	-1.7	-1.7	-1.8	-1.3	1.8	-1.3	-1.1	1.6
Medication: Ibuprofen	0.7	0.8	1.4	0.4	0.7	-0.9	-0.8	-0.7	-0.8	1.2	0.2	1.0	0.9	0.9	0.7	1.1	-0.9	1.2	1.2	-0.9
Medication: Allopurinol	0.5	0.7	1.2	1.0	1.1	-0.8	1.1	-0.7	-0.5	0.9	1.0	0.9	0.8	0.7	0.7	0.8	-0.4	0.7	0.9	-0.7
Medication: Omeprazole	1.7	2.0	3.3	-1.4	-1.7	1.6	0.4	1.0	1.3	-1.5	-1.4	-1.8	-1.6	-1.5	-1.3	-1.5	1.4	-1.4	-1.5	1.4
Medication: Seretide 50 evohaler	0.2	0.2	0.8	-0.3	0.1	-0.2	-0.9	-0.5	-0.6	0.4	0.1	0.4	0.4	0.4	0.5	0.3	-0.7	0.9	0.3	-0.4
Mean time to correctly identify matches	0.1	0.2	1.0	-0.1	0.3	-0.4	-1.0	-0.1	-0.3	0.8	-0.0	0.5	0.1	0.3	0.2	0.5	-0.3	0.1	0.7	-0.4
Heart disease (mother)	3.3	4.0	10.6	-3.2	-2.4	2.2	1.9	2.3	2.0	-1.8	-2.2	-1.9	-1.5	-1.8	-1.3	-1.6	2.3	-0.4	-1.8	1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	2.9	1.4	0.8	-1.3	-1.7	-1.1	-1.3	1.6	1.0	1.0	1.2	1.0	1.3	1.4	-1.2	1.2	1.4	-1.3
Whole body fat mass	0.1	0.4	1.3	-1.0	-0.9	0.5	-0.3	0.6	0.6	-0.1	-1.2	-0.5	-0.7	-0.4	-0.4	-0.4	0.7	-0.2	-0.2	0.6
Leg fat mass (right)	0.0	0.1	0.7	-0.8	-0.5	0.2	0.1	0.4	0.4	0.2	-0.7	-0.2	-0.4	-0.1	-0.2	-0.1	0.5	0.1	0.1	0.4
Arm predicted mass (right)	0.0	0.2	0.6	-0.1	0.5	-0.6	0.3	-0.2	-0.3	0.6	0.4	0.6	0.4	0.7	0.6	0.5	-0.2	0.4	0.6	-0.3
Pulse rate, automated reading	0.7	2.4	4.0	-1.6	-1.1	1.6	1.2	1.7	1.8	-1.0	-1.3	-1.1	-1.9	-1.4	-1.8	-1.6	1.6	-2.0	-1.2	1.8
Alcohol intake frequency.	0.3	0.7	1.8	-0.9	-0.4	0.7	1.1	1.0	1.3	-0.1	-1.1	-0.2	-0.5	-0.7	-1.1	-0.5	1.4	-0.0	-0.2	1.0
Comparative height size at age 10	0.3	1.4	4.1	0.4	0.9	-1.5	-0.8	-1.0	-1.1	1.0	0.7	1.1	1.5	1.4	1.5	1.2	-0.8	2.0	1.0	-1.1
Number of full sisters	4.2	5.2	8.8	-1.5	-2.1	2.6	1.9	1.5	2.1	-2.7	-1.2	-2.5	-2.6	-2.6	-2.5	-2.5	1.6	-3.0	-2.6	2.3
Suffer from ‘nerves’	3.4	5.3	7.6	-2.0	-2.3	2.2	2.3	2.8	2.6	-2.0	-2.5	-2.1	-2.5	-2.3	-2.2	-2.1	2.6	-2.2	-2.0	2.4
Overall health rating	3.5	7.6	9.9	-2.3	-2.4	2.9	2.4	3.1	3.0	-2.8	-2.2	-2.7	-2.8	-2.7	-2.8	-2.9	3.1	-2.5	-2.8	3.0
Chest pain or discomfort	1.1	1.6	2.8	0.8	1.4	-1.2	-0.2	-0.7	-1.1	1.6	1.4	1.3	1.4	1.3	1.3	1.4	-1.0	1.7	1.6	-1.2
Had major operations	1.3	1.5	3.1	1.6	1.8	-1.4	0.7	-0.8	-1.0	1.5	1.6	1.5	0.9	1.3	0.9	1.1	-1.1	0.3	1.4	-1.0
Age at last live birth	0.5	0.8	2.6	-0.2	-0.6	0.6	-1.6	0.6	0.9	-1.0	-0.5	-0.8	-0.6	-1.0	-1.0	-1.0	0.7	-0.9	-1.0	0.9
Family relationship satisfaction	2.4	3.0	5.5	2.0	1.8	-1.7	-2.4	-1.3	-1.6	2.0	1.5	1.9	1.7	1.8	1.5	1.8	-1.4	1.3	2.0	-1.6
Leg pain on walking	0.4	0.5	1.1	-0.6	-0.7	0.5	0.3	0.6	0.7	-0.8	-0.8	-0.5	-1.0	-0.6	-0.7	-0.8	0.6	-1.0	-0.8	0.7
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	3.0	-0.9	-1.2	1.5	1.7	0.9	1.6	-1.5	-1.3	-1.1	-1.3	-1.4	-1.6	-1.4	1.6	-1.4	-1.4	1.4
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.6	-1.2	-0.4	0.3	0.4	1.0	0.5	0.1	-1.1	0.1	-0.2	0.2	-0.1	-0.1	0.8	0.6	0.1	0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.7	0.0	0.5	-0.4	-1.3	-0.1	-0.2	0.6	-0.1	0.7	0.4	0.5	0.2	0.4	-0.3	0.5	0.6	-0.2
Medication: Aspirin	1.8	2.4	4.4	-1.6	-1.6	1.7	0.5	2.0	1.7	-1.4	-1.8	-1.4	-1.6	-1.2	-1.3	-1.4	2.1	-1.4	-1.3	1.7
Supplements: Vitamin C	1.1	1.4	2.9	0.9	1.4	-1.3	-1.7	-1.2	-1.1	1.1	1.4	1.1	1.2	0.9	0.8	0.9	-1.3	0.8	0.9	-1.2
Knee pain experienced in last month	0.2	0.2	0.7	-0.1	0.0	-0.3	0.6	-0.6	-0.7	0.5	0.4	0.2	0.3	0.4	0.7	0.5	-0.8	0.7	0.4	-0.5
Hypertension (Self-reported)	0.2	0.6	1.1	-1.1	-0.7	0.8	0.7	0.8	0.8	-0.6	-0.6	-0.9	-0.9	-0.9	-0.9	-0.8	0.8	-0.8	-0.7	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	2.6	-1.2	-1.0	1.6	1.6	1.2	1.2	-0.5	-1.0	-1.3	-1.4	-1.5	-1.6	-1.3	0.9	-1.5	-0.8	1.4
Illnesses of father: Heart disease	1.1	1.6	3.6	-1.9	-1.1	1.4	0.4	1.8	1.5	-0.9	-1.7	-1.0	-1.0	-0.9	-1.0	-1.0	1.6	-0.4	-0.9	1.3
Illnesses of siblings: Diabetes	1.0	1.3	3.3	-1.3	-1.2	0.9	1.8	1.3	1.0	-1.4	-1.0	-1.1	-0.9	-0.8	-0.6	-1.1	1.0	-0.5	-1.4	1.1
Smoking status: Previous	0.2	0.3	1.7	0.8	0.2	-0.7	-1.3	-0.2	-0.5	0.2	0.5	0.3	0.7	0.4	0.7	0.4	-0.4	0.7	0.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	2.9	6.0	8.5	-2.4	-1.9	2.6	1.9	2.9	2.6	-2.4	-2.1	-2.4	-2.4	-2.3	-2.5	-2.8	2.5	-2.3	-2.6	2.8
Whole body fat-free mass	0.0	0.2	0.6	-0.1	0.4	-0.5	-0.1	-0.2	-0.3	0.8	0.3	0.5	0.5	0.8	0.6	0.5	-0.0	0.5	0.6	-0.3
Leg fat-free mass (right)	0.0	0.1	0.4	-0.5	-0.0	-0.1	-0.6	0.2	0.3	0.4	-0.3	0.1	-0.0	0.2	-0.1	-0.0	0.4	0.0	0.2	0.3
Arm fat percentage (left)	0.0	0.2	1.5	0.0	-0.1	-0.1	-1.2	-0.3	-0.2	0.7	-0.4	0.1	0.0	0.2	0.1	0.3	-0.1	0.1	0.5	-0.2
Average weekly red wine intake	2.2	3.3	5.4	1.8	2.1	-1.7	-2.3	-1.9	-1.6	2.0	2.0	1.8	1.9	1.6	1.4	1.7	-1.6	1.3	1.9	-1.7
Handedness (chirality/laterality): Left-handed	2.6	3.1	4.9	1.6	1.8	-1.7	-0.2	-1.6	-1.6	2.2	1.8	1.8	1.9	1.6	1.8	2.0	-1.6	1.7	2.1	-1.9
Mood swings	0.1	0.2	0.8	-0.1	-0.0	-0.2	0.9	-0.3	-0.1	0.7	0.1	-0.0	0.3	0.0	0.4	0.5	0.2	0.7	0.5	-0.4
Loneliness, isolation	0.3	0.5	1.7	1.0	1.1	-0.5	0.4	-0.7	-0.5	0.6	1.3	0.6	0.6	0.3	0.1	0.6	-0.5	-0.0	0.6	-0.7
Long-standing illness, disability or infirmity	0.1	0.1	0.4	-0.4	-0.2	0.2	0.6	0.6	0.5	-0.1	-0.3	-0.1	-0.3	-0.1	-0.3	-0.2	0.7	0.0	-0.1	0.4
Ever had bowel cancer screening	0.0	0.1	0.4	-0.3	0.1	0.0	-0.4	0.1	-0.0	0.6	-0.2	-0.1	-0.2	0.0	0.1	0.1	0.1	-0.3	0.4	-0.1
Diabetes diagnosed by doctor	0.5	0.8	2.4	1.1	0.7	-0.8	-1.5	-1.0	-0.9	0.9	0.8	0.7	0.6	0.9	1.1	1.0	-0.7	0.2	0.9	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.3	1.5	1.1	-0.4	-0.8	-0.8	-0.6	0.2	1.5	0.4	0.6	0.3	0.3	0.3	-0.9	-0.3	0.2	-0.5
Friendships satisfaction	2.2	2.7	4.9	1.9	1.5	-1.5	-0.9	-1.2	-1.5	2.2	1.4	1.6	1.7	1.9	1.8	1.9	-1.2	1.5	2.2	-1.6
Qualifications: nursing, teaching	1.7	2.7	4.3	-0.8	-1.8	2.1	-0.8	1.6	1.6	-1.9	-1.4	-2.1	-1.5	-1.7	-1.4	-1.7	1.7	-1.7	-1.8	1.6
Commuting to job workplace: Walk	3.7	4.0	6.5	2.1	1.8	-2.1	-0.8	-2.5	-2.3	2.0	2.0	1.7	2.0	1.8	2.0	1.9	-2.4	1.8	1.9	-2.2
Eye problems/disorders: Cataract	1.6	1.8	3.1	-0.9	-1.2	1.2	-0.1	1.8	1.6	-1.0	-1.4	-1.1	-1.6	-1.3	-1.6	-1.3	1.7	-1.7	-0.9	1.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.2	-0.9	-0.6	0.7	1.1	0.9	0.7	-0.6	-0.7	-0.6	-0.6	-0.6	-0.4	-0.6	0.8	-0.2	-0.7	0.6
Medication for cholesterol	0.1	0.1	0.7	0.1	0.0	-0.2	-0.6	-0.8	-0.4	0.1	-0.1	-0.0	-0.1	0.2	0.1	-0.1	-0.5	-0.1	-0.0	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.3	4.4	-1.2	-1.4	1.5	2.1	1.8	1.5	-1.5	-0.9	-1.5	-1.5	-1.3	-1.3	-1.4	1.6	-1.9	-1.5	1.4
Back pain experienced in last month	1.3	1.8	4.0	-2.0	-1.4	1.2	2.0	1.2	1.4	-1.2	-1.4	-1.4	-1.2	-1.4	-1.2	-1.2	1.4	-0.5	-1.3	1.1
Mineral and other dietary supplements	0.3	0.4	1.0	-0.1	-0.6	0.7	0.2	0.2	0.5	-0.9	-0.2	-0.9	-0.6	-0.7	-0.3	-0.7	0.5	-1.0	-0.9	0.5
Breast cancer (self-reported)	0.9	1.1	3.2	1.1	0.5	-1.1	-1.0	-1.8	-1.4	0.8	0.7	0.5	0.6	0.5	1.0	0.9	-1.7	0.5	0.7	-1.4
Asthma (self-reported)	0.7	1.4	2.4	-1.4	-1.5	1.1	1.3	1.5	1.2	-0.7	-1.4	-1.3	-1.0	-1.6	-1.3	-1.0	0.8	-0.5	-0.9	1.1
Osteoporosis (self-reported)	7.1	8.8	14.4	3.1	2.9	-3.0	-1.7	-3.8	-3.6	2.5	3.5	2.5	2.8	3.1	3.3	2.7	-3.4	2.3	2.5	-3.3
Osteoarthritis (self-reported)	0.3	0.4	1.1	-0.3	0.1	-0.6	-0.6	-0.7	-0.7	0.7	-0.1	0.4	0.5	0.5	0.6	0.6	-0.8	1.1	0.6	-0.6
Medication: Aspirin	1.2	1.6	2.9	-1.2	-1.3	1.4	0.1	1.7	1.4	-1.3	-1.3	-1.2	-1.3	-0.9	-1.1	-1.2	1.7	-1.3	-1.2	1.4
Medication: Gliclazide	0.2	0.2	0.9	-0.1	-0.7	0.5	-0.5	0.2	-0.1	-0.7	0.0	-0.9	-0.2	-0.3	0.5	-0.3	0.1	-0.1	-0.7	0.1
Illnesses of father: None of the above (group 1)	0.8	1.0	2.8	1.6	1.0	-1.0	-0.2	-1.7	-1.3	0.8	1.3	0.8	0.6	0.8	0.7	0.6	-1.5	-0.1	0.7	-0.9
Smoking status: Current	0.7	1.1	1.8	1.0	1.1	-1.4	-0.3	-1.0	-1.3	0.8	1.0	1.1	1.1	1.3	1.2	0.9	-1.2	1.2	0.9	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	2.7	-0.9	-1.3	1.4	-1.3	1.5	1.4	-0.8	-1.5	-1.3	-1.3	-1.6	-1.6	-1.3	1.1	-1.6	-1.0	1.4
Whole body water mass	0.1	0.3	0.8	0.1	0.5	-0.7	-0.1	-0.3	-0.4	0.9	0.4	0.7	0.6	0.9	0.7	0.6	-0.2	0.6	0.8	-0.4
Leg predicted mass (right)	0.0	0.1	0.4	-0.5	-0.1	0.0	-0.7	0.3	0.3	0.3	-0.4	0.1	-0.1	0.1	-0.1	-0.1	0.5	-0.0	0.2	0.3
Arm fat mass (left)	0.0	0.1	0.6	-0.1	-0.0	-0.3	-0.5	-0.3	-0.2	0.8	-0.3	0.2	0.1	0.3	0.2	0.4	-0.1	0.3	0.6	-0.3
Number of self-reported non-cancer illnesses	1.3	2.3	3.5	-1.7	-1.8	1.4	0.3	1.9	1.6	-0.9	-1.7	-1.4	-1.8	-1.6	-1.6	-1.5	1.3	-1.4	-1.2	1.6
Average weekly champagne plus white wine intake	0.8	1.1	3.8	1.1	0.3	-1.0	-2.0	-1.1	-1.5	0.8	0.7	0.3	0.8	0.6	1.2	1.0	-1.6	0.6	0.8	-1.3
Miserableness	1.4	2.3	3.1	1.4	1.6	-1.7	-0.7	-1.4	-1.6	1.7	1.8	1.5	1.6	1.5	1.6	1.6	-1.4	1.6	1.6	-1.6
Guilty feelings	0.7	1.0	3.5	-0.8	-0.9	1.1	1.9	0.6	0.9	-0.8	-0.2	-1.0	-1.1	-1.2	-1.1	-1.0	0.5	-1.2	-0.9	1.0
Wears glasses or contact lenses	0.8	0.9	2.0	0.6	0.8	-1.0	-1.2	-0.8	-0.7	1.4	0.1	1.2	0.8	1.0	0.6	1.0	-0.7	1.2	1.3	-0.8
Ever taken oral contraceptive pill	0.7	0.8	1.6	-0.9	-0.7	1.1	1.2	1.3	1.0	-0.6	-0.7	-0.9	-0.7	-1.0	-0.8	-0.8	0.8	-0.6	-0.7	1.0
Hearing aid user	0.0	0.0	0.2	0.1	-0.0	-0.3	-0.2	-0.4	-0.0	0.0	0.1	0.3	-0.2	0.1	-0.3	-0.1	-0.1	-0.3	0.0	0.0
Mother’s age at death	0.3	0.3	2.8	0.9	0.4	-0.5	-1.7	-0.6	-0.4	0.3	0.4	0.2	0.1	0.2	-0.0	0.2	-0.4	-0.7	0.3	-0.4
Financial situation satisfaction	1.2	1.4	3.5	0.6	0.6	-1.2	-1.0	-1.1	-1.1	1.4	0.6	1.1	1.3	1.4	1.6	1.3	-0.8	1.9	1.4	-1.1
Tinnitus: Yes, now most or all of the time	0.3	0.3	2.1	-0.4	-0.1	0.4	1.4	0.7	0.7	-0.1	-0.2	-0.0	-0.4	-0.3	-0.6	-0.3	0.8	-0.1	-0.0	0.5
Commuting to job workplace: Public transport	4.3	5.1	7.2	2.7	2.2	-2.2	-2.1	-2.1	-2.1	2.5	2.0	2.0	2.5	1.7	2.0	2.5	-2.2	2.2	2.5	-2.5
Eye problems/disorders: Glaucoma	0.3	0.3	0.7	-0.2	-0.9	0.4	-0.7	0.5	0.2	-0.6	-0.6	-0.7	-0.7	-0.6	-0.4	-0.6	0.1	-0.6	-0.6	0.5
Medication: Blood pressure	0.4	0.7	1.1	-1.0	-0.9	0.9	0.8	0.9	1.0	-0.9	-0.8	-0.8	-0.8	-1.0	-0.9	-0.8	1.0	-0.5	-0.9	0.7
Pain type(s) experienced in last month: Hip pain	1.6	2.0	2.8	-1.5	-1.4	1.5	1.4	1.1	1.1	-1.4	-1.1	-1.7	-1.6	-1.4	-1.3	-1.5	1.0	-1.7	-1.4	1.4
Supplements: Fish oil (including cod liver oil)	0.9	1.2	1.9	-1.2	-1.0	1.2	1.4	1.4	1.1	-0.8	-1.1	-1.0	-1.1	-1.2	-1.4	-1.1	0.9	-0.8	-0.9	1.2
High cholesterol (Self-reported)	0.6	1.0	2.0	-0.6	-1.1	1.1	1.0	1.0	1.1	-0.9	-0.7	-1.3	-1.0	-1.4	-0.9	-0.9	1.1	-1.0	-1.0	0.8
Medication: Bendroflumethiazide	0.6	0.9	1.8	-1.3	-1.0	0.9	0.7	1.3	1.1	-0.5	-1.3	-0.7	-0.9	-0.6	-0.7	-1.0	1.2	-0.7	-0.8	1.2
Medication: Paracetamol	6.0	9.3	11.6	-2.8	-2.7	3.2	3.2	3.2	3.3	-2.5	-2.9	-2.8	-3.4	-3.0	-3.4	-3.0	3.3	-3.2	-2.6	3.2
Medication: Lisinopril	0.2	0.3	1.3	0.5	0.2	0.3	1.1	0.3	0.4	-0.3	0.5	-0.1	-0.5	-0.4	-0.5	-0.3	0.3	-1.1	-0.3	0.2
Medication: Atorvastatin	0.3	0.4	1.8	-0.4	-0.9	0.3	-1.2	-0.2	-0.1	-1.4	0.0	-1.0	-0.3	-0.5	0.2	-0.5	-0.1	-0.1	-1.1	0.1
Illnesses of father: High blood pressure	0.1	0.1	0.4	0.5	0.3	-0.3	-0.3	-0.3	0.0	-0.1	0.4	0.2	0.5	0.1	0.2	0.3	0.2	0.6	0.0	-0.3
Alcohol drinker status: Never	0.2	0.2	2.4	-0.7	-0.6	0.3	1.5	-0.3	0.1	-0.3	-0.2	-0.3	-0.3	-0.2	-0.1	-0.3	0.0	0.2	-0.4	0.2
Ever smoked	3.2	5.7	8.3	2.9	2.3	-2.8	-1.5	-2.1	-2.4	2.2	2.4	2.3	2.6	2.2	2.4	2.4	-2.4	2.5	2.2	-2.5
Basal metabolic rate	0.0	0.1	0.3	-0.3	0.1	-0.3	0.1	0.0	-0.0	0.5	-0.0	0.3	0.2	0.5	0.3	0.2	0.2	0.3	0.4	-0.0
Leg fat percentage (left)	0.1	0.3	0.9	-0.9	-0.8	0.5	0.3	0.6	0.6	-0.3	-0.9	-0.4	-0.7	-0.4	-0.4	-0.4	0.8	-0.2	-0.3	0.5
Arm fat-free mass (left)	0.0	0.2	0.6	-0.6	0.0	-0.5	0.7	-0.2	-0.3	0.5	0.0	0.3	0.3	0.7	0.7	0.4	-0.0	0.8	0.4	-0.2
Number of operations (self-reported)	0.2	0.3	0.9	0.9	0.7	-0.7	-1.0	-0.1	-0.2	0.7	0.8	0.6	0.2	0.3	0.0	0.4	-0.3	-0.2	0.6	-0.3
Average weekly beer plus cider intake	2.5	3.7	6.5	-2.5	-1.6	2.1	1.1	1.9	2.2	-1.7	-1.9	-1.6	-2.0	-1.7	-2.1	-2.1	2.0	-1.6	-1.8	2.4
Irritability	0.1	0.1	1.4	-0.8	-0.1	0.1	1.2	0.1	0.0	-0.1	0.0	-0.2	-0.0	0.1	0.3	-0.0	0.3	0.3	-0.1	-0.0
Risk taking	1.2	1.8	2.5	-1.5	-1.4	1.4	1.6	1.0	1.2	-1.6	-0.8	-1.5	-1.3	-1.3	-1.1	-1.4	1.3	-1.1	-1.5	1.3
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.3	-0.5	-0.2	0.7	0.3	1.5	1.2	-0.2	-0.7	-0.2	-1.0	-0.9	-1.5	-0.7	1.1	-0.9	-0.3	1.0
Fractured/broken bones in last 5 years	2.1	2.8	3.9	1.0	1.7	-1.6	-0.4	-1.6	-1.7	1.8	2.0	1.6	1.9	1.9	1.8	1.7	-1.3	1.9	1.8	-1.7
Age started oral contraceptive pill	6.1	7.6	13.5	2.3	2.5	-2.9	-3.7	-2.5	-2.7	2.9	2.0	2.8	2.7	3.0	2.9	2.9	-2.5	2.5	2.9	-2.8
Diastolic blood pressure, automated reading	0.3	1.1	1.9	-1.1	-0.5	1.1	1.2	1.3	1.4	-0.7	-0.7	-0.6	-0.9	-1.0	-1.4	-1.0	1.1	-0.8	-0.8	1.2
Ever depressed for a whole week	0.5	0.6	2.9	-0.2	0.2	-0.6	-0.9	-0.0	-0.0	1.2	-0.8	0.9	0.6	0.6	0.5	0.9	-0.0	1.7	1.2	-0.4
Unable to work because of sickness or disability	0.1	0.2	0.5	-0.3	-0.1	0.4	-0.2	0.1	0.5	-0.3	-0.1	-0.1	-0.5	-0.3	-0.7	-0.5	0.6	-0.6	-0.3	0.5
Commuting to job workplace: Cycle	3.0	3.6	6.2	1.8	1.6	-1.7	-2.1	-2.4	-2.4	1.3	2.2	1.3	2.0	1.5	1.9	1.7	-2.5	1.5	1.4	-2.2
Myopia	0.1	0.2	1.6	0.6	-0.0	0.1	-1.3	0.0	0.1	-0.4	-0.0	-0.1	-0.2	-0.2	-0.2	-0.4	-0.1	-0.8	-0.5	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.6	0.8	0.4	-0.4	-0.5	-0.5	-0.5	0.3	0.2	0.5	0.4	0.4	0.3	0.4	-0.5	0.3	0.3	-0.5
Cholesterol lowering medication	0.2	0.3	1.1	1.0	0.9	-0.5	0.2	-0.6	-0.2	0.2	0.9	0.6	0.7	0.3	0.1	0.6	-0.0	0.5	0.5	-0.6
Medication: Omeprazole (e.g. Zanprol)	3.0	3.6	5.4	-1.8	-2.3	2.1	1.0	1.4	1.7	-2.1	-1.7	-2.3	-2.1	-1.9	-1.7	-2.1	1.8	-1.9	-2.1	1.9
Pain experienced in last month	4.0	6.6	10.0	2.4	2.7	-2.8	-3.2	-2.3	-2.3	2.4	1.8	2.9	2.9	2.8	2.6	2.6	-2.0	2.9	2.5	-2.5
Supplements: Calcium	1.1	1.2	1.8	0.4	0.7	-1.2	-0.9	-1.4	-1.2	1.1	0.8	1.0	1.2	1.2	1.1	1.1	-1.1	1.3	1.1	-1.2
Basal cell carcinoma (self-reported)	0.5	0.6	2.0	0.2	-0.6	0.9	-0.0	0.8	0.9	-0.3	-0.7	-0.8	-0.9	-1.1	-1.1	-0.5	0.9	-1.4	-0.3	0.6
Heart attack/myocardial infarction (self-reported)	0.8	1.0	6.3	0.4	0.4	-0.8	-2.5	-0.3	-0.8	0.7	0.1	0.7	1.1	0.9	1.1	0.9	-0.7	1.3	0.7	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	1.7	-0.0	0.1	-0.0	1.3	-0.2	-0.2	0.2	0.6	-0.2	0.1	-0.1	0.1	0.1	-0.3	-0.1	0.1	-0.2
Heart disease (siblings)	0.3	0.3	1.4	-1.1	-0.7	0.5	1.2	0.4	0.3	-0.1	-1.1	-0.4	-0.3	-0.1	-0.0	-0.1	0.6	0.2	-0.1	0.2
Alcohol drinker status: Previous	3.0	3.4	7.0	-1.9	-1.4	1.6	2.2	2.5	2.4	-1.2	-2.1	-1.2	-1.7	-1.6	-2.2	-1.5	2.6	-1.1	-1.1	2.0
Pack years of smoking	5.1	7.4	11.9	3.3	3.5	-2.9	-0.6	-2.6	-2.3	3.3	3.1	3.2	2.4	2.8	2.4	2.9	-2.2	1.6	3.2	-2.6
Impedance of whole body	1.8	9.2	12.7	-2.5	-3.4	3.3	1.7	3.0	3.0	-3.6	-3.2	-3.4	-3.0	-3.4	-3.0	-3.2	2.7	-2.6	-3.4	3.0
Leg fat mass (left)	0.1	0.2	0.9	-0.9	-0.6	0.3	0.0	0.4	0.5	-0.0	-0.8	-0.3	-0.5	-0.2	-0.3	-0.2	0.7	0.0	-0.1	0.5
Arm predicted mass (left)	0.0	0.1	0.4	-0.4	-0.0	-0.4	0.7	-0.3	-0.2	0.4	0.1	0.2	0.2	0.5	0.5	0.3	0.0	0.5	0.3	-0.2