TWAS hub - CMTR2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1600	0.0620	2.7e-04	0.051	NA	0.021	NA	0.024	5.1e-05	NA	7.3e-03	NA	0.0041
2	GTEx	Adipose Visceral Omentum	0.2040	0.0750	9.2e-05	0.040	NA	0.125	NA	0.041	3.9e-03	NA	4.8e-07	NA	0.0034
3	GTEx	Artery Aorta	0.1630	0.0650	2.5e-04	0.044	NA	0.028	NA	0.026	1.8e-03	NA	1.1e-02	NA	0.0140
4	GTEx	Artery Tibial	0.0799	0.0369	1.5e-03	0.007	NA	0.006	NA	0.007	9.2e-02	NA	1.0e-01	NA	0.0850
5	GTEx	Cells EBV-transformed lymphocytes	0.1440	0.0700	9.9e-03	0.077	NA	0.074	NA	0.065	1.7e-03	NA	2.1e-03	NA	0.0038
6	GTEx	Cells Transformed fibroblasts	0.1170	0.0480	1.1e-03	0.006	NA	0.031	NA	0.017	1.0e-01	NA	2.2e-03	NA	0.0190
7	GTEx	Liver	0.1900	0.0930	7.6e-03	0.052	NA	0.019	NA	0.015	1.5e-02	NA	9.8e-02	NA	0.1200
8	GTEx	Lung	0.0924	0.0373	1.4e-04	0.003	NA	0.010	NA	0.014	1.8e-01	NA	5.6e-02	NA	0.0300
9	GTEx	Nerve Tibial	0.1053	0.0479	6.3e-04	0.001	NA	0.001	NA	0.004	2.6e-01	NA	2.7e-01	NA	0.1600
10	GTEx	Skin Not Sun Exposed Suprapubic	0.1030	0.0530	4.6e-03	-0.005	NA	-0.005	NA	-0.004	9.6e-01	NA	9.9e-01	NA	0.5900
11	METSIM	Adipose	0.0433	0.0191	3.5e-04	0.010	0.014	0.014	0.016	0.015	8.8e-03	0.0027	2.7e-03	0.0014	0.0019

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Irritability	9.6	16.2	30.8	-1.5	-3.9	-4.0	-4.3	-3.4	-4.0	-0.8	-5.1	-5.1	-4.0	-5.5
Mood swings	7.0	12.7	24.4	-3.0	-3.2	-3.1	-4.3	-3.6	-2.7	-2.1	-3.6	-3.9	-4.0	-4.9
Depressed Affect (Nagel 2018)	6.2	13.1	26.8	-2.5	-3.2	-3.7	-4.1	-4.0	-2.2	-2.9	-3.3	-3.9	-3.8	-5.2
Fractured/broken bones in last 5 years	5.8	7.4	17.1	-1.5	-2.8	-3.1	-2.9	-2.0	-0.2	-2.2	-4.1	-3.6	-1.9	-3.3
Risk taking	5.5	8.0	17.4	-1.3	-1.5	-2.4	-3.8	-2.9	0.3	-2.8	-3.8	-4.2	-2.3	-3.1
Depression (Nagel 2018)	5.3	8.0	17.2	-2.2	-2.5	-2.8	-3.0	-3.5	-1.6	-2.0	-2.3	-2.3	-3.7	-4.1
LDL Cholesterol	5.2	8.2	16.3	2.1	2.9	1.9	3.4	2.1	3.5	0.9	3.6	2.9	2.6	4.0
Neuroticism (Nagel 2018)	5.1	11.9	24.1	-2.0	-3.3	-2.5	-3.7	-3.0	-3.5	-2.4	-3.9	-3.8	-4.0	-4.9
Neck or shoulder pain in last month	4.6	6.5	15.7	-1.9	-3.2	-1.1	-3.2	-2.5	-0.9	-1.4	-1.7	-2.7	-3.4	-4.0
Tense / ‘highly strung’	4.4	7.3	16.8	-0.3	-2.3	-0.7	-2.4	-0.2	-2.7	-0.6	-3.6	-4.1	-4.0	-3.9
Fed-up feelings	4.3	7.8	16.1	-1.4	-2.9	-2.3	-2.8	-2.9	-2.8	-1.0	-2.8	-3.6	-2.8	-4.0
Neuroticism	4.2	10.2	19.1	-1.9	-2.9	-2.4	-3.7	-2.2	-3.3	-1.7	-4.0	-3.7	-3.6	-4.4
Osteoporosis (self-reported)	4.2	5.2	9.9	-2.6	-2.2	-2.7	-3.1	-2.2	0.1	-2.0	-3.0	-1.9	-1.5	-2.0
Neuroticism (2016)	4.0	5.8	11.2	-0.6	-1.9	-1.7	-2.4	-1.9	-3.3	0.1	-3.3	-3.4	-2.6	-2.7
Loneliness, isolation	3.9	5.4	10.0	-1.8	-1.5	-2.6	-2.6	-2.5	-1.2	-1.9	-2.3	-2.1	-3.0	-3.2
Illnesses of father: Heart disease	3.6	4.9	11.8	-2.2	-1.9	-3.4	-2.3	-3.1	-2.0	-2.3	-2.1	-1.4	-0.3	-2.0
Health satisfaction	3.4	4.4	8.7	-1.8	-1.9	-1.1	-2.3	-1.7	-2.5	-1.1	-2.6	-2.2	-2.1	-2.9
Age at First Birth	3.3	4.8	10.1	0.5	2.4	1.4	1.9	1.2	3.2	0.6	2.5	3.0	2.3	2.8
Age at first live birth	3.3	5.9	14.7	1.1	2.2	1.3	2.8	2.8	2.9	1.6	2.4	2.8	1.9	3.8
Commuting to job workplace: Car/motor vehicle	3.3	3.8	7.2	-2.2	-2.7	-1.6	-2.1	-2.1	-0.4	-2.2	-0.6	-0.7	-2.5	-2.5
Relative age voice broke	3.2	4.9	14.2	-0.8	-2.5	-0.7	-2.4	-1.4	-1.6	-0.6	-2.8	-3.8	-2.3	-2.9
Qualifications: O levels/GCSEs or equivalent	3.2	5.0	9.7	2.3	1.7	1.4	3.0	2.7	2.5	1.9	2.1	1.5	1.5	3.1
Neuroticism score	3.1	6.5	14.3	-0.9	-1.9	-1.7	-2.6	-1.4	-2.7	-0.8	-3.2	-3.3	-3.5	-3.8
Guilty feelings	3.1	4.7	14.2	-1.2	-1.7	-1.4	-2.5	-1.6	-3.8	-0.8	-2.4	-1.9	-2.4	-2.7
Falls in the last year	3.0	4.1	7.6	-1.8	-2.8	-2.6	-2.2	-2.6	-1.1	-0.9	-2.4	-2.6	0.7	-1.0
Systolic Blood Pressure	2.9	14.7	28.2	5.3	4.0	4.2	4.4	4.5	1.8	2.6	3.2	2.7	3.4	4.7
Smoking Status	2.8	6.7	13.9	-2.4	-2.7	-3.7	-3.0	-3.3	-0.9	-1.8	-3.0	-2.9	0.2	-2.4
Back pain experienced in last month	2.8	4.1	9.7	-2.3	-2.5	-1.8	-2.6	-2.5	-1.6	-0.8	-1.3	-0.6	-1.5	-3.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.7	3.6	9.4	-1.1	-1.4	-1.4	-2.3	-2.0	-0.3	-1.8	-2.0	-1.5	-2.5	-3.1
Chest pain or discomfort	2.6	3.8	11.5	-0.2	-1.5	-0.5	-1.6	-0.6	-2.7	-2.2	-3.4	-2.6	-1.2	-2.1
Commuting to job workplace: Walk	2.6	2.8	5.8	1.0	1.1	2.1	1.6	2.3	1.9	2.4	1.6	0.4	0.2	1.9
Age started oral contraceptive pill	2.6	3.3	7.2	2.0	1.4	1.7	2.7	1.6	-0.3	1.3	2.2	1.6	1.4	2.5
Relative age of first facial hair	2.5	5.1	10.0	-1.2	-3.2	-1.9	-2.0	-2.5	-3.0	-1.8	-2.3	-3.0	-1.0	-2.0
Commuting to job workplace: Cycle	2.5	3.1	9.9	1.6	1.6	-0.2	1.2	1.1	3.0	-0.3	1.3	1.5	3.1	1.9
Medication: Aspirin	2.4	3.2	7.0	-1.1	-1.8	-2.6	-1.9	-1.9	-0.6	-2.3	-2.1	-1.9	0.0	-1.7
Happiness	2.2	2.6	4.6	-0.7	-1.2	-1.8	-1.3	-1.8	-2.0	-0.2	-1.9	-2.1	-1.5	-2.1
Frequency of depressed mood in last 2 weeks	2.1	2.9	6.2	-1.0	-1.4	-1.6	-1.7	-2.0	-0.8	-0.3	-1.7	-1.9	-2.5	-2.5
Had major operations	2.1	2.5	4.8	1.9	1.0	2.0	1.8	1.7	1.7	2.2	1.5	-0.3	-0.1	1.5
Friendships satisfaction	2.1	2.6	8.9	-1.3	-1.0	-1.8	-1.1	-2.0	-3.0	-1.9	-1.7	-0.2	-0.1	-1.5
Medication: Atorvastatin	2.1	2.6	6.7	0.7	1.4	1.2	1.8	1.0	1.9	0.6	1.6	1.9	1.9	2.6
Schizophrenia (2014)	2.0	4.5	13.3	-3.2	-2.3	-1.6	-1.7	-3.6	-2.5	-2.1	-0.2	-0.3	-0.9	-1.8
Systolic blood pressure, automated reading	2.0	5.9	12.4	3.3	2.4	3.1	2.4	3.5	1.0	1.3	1.7	1.7	1.9	2.8
Medication: Cholesterol lowering	2.0	3.1	10.4	1.2	1.5	0.8	1.5	1.0	3.2	-0.0	1.3	1.4	2.5	2.6
Had other major operations	1.9	2.3	6.3	-0.4	-1.2	0.8	-1.3	-1.0	-2.5	-0.3	-1.5	-2.1	-2.2	-1.7
Overall health rating	1.9	4.2	10.7	-0.9	-1.4	-1.4	-2.4	-2.3	-2.9	-1.4	-2.5	-1.4	-0.9	-3.3
Supplements: Vitamin C	1.9	2.3	9.4	-0.2	-1.2	-0.4	-1.0	-0.4	-0.6	0.8	-1.3	-3.1	-2.8	-1.5
Medication: Gliclazide	1.9	2.1	5.2	-1.3	-1.1	-0.8	-1.9	-0.9	-1.2	-1.1	-1.4	-1.4	-1.8	-2.3
Financial situation satisfaction	1.9	2.3	5.2	-1.6	-0.5	-2.3	-1.7	-1.9	-0.8	-2.0	-1.5	-0.9	-0.4	-1.8
Schizophrenia (2018)	1.8	3.7	13.8	-2.6	-2.3	-1.6	-1.4	-3.7	-2.4	-1.5	-0.1	-0.5	-0.5	-1.5
Diabetes (father)	1.8	2.3	6.5	1.2	1.5	1.1	1.8	1.0	1.1	2.6	1.5	1.2	1.3	1.6
Chronic bronchitis/emphysema (father)	1.8	2.1	10.5	0.8	1.0	2.0	1.1	1.6	0.7	3.2	0.8	0.6	-1.1	0.4
Qualifications: None of the above	1.8	3.8	9.1	-2.7	-1.2	-1.1	-2.4	-3.0	-0.5	-2.6	-0.2	0.5	-1.6	-2.7
Loud music exposure frequency	1.7	1.8	4.0	-1.9	0.1	-1.2	-2.0	-1.2	1.3	-1.8	-0.9	0.7	-0.8	-1.6
Medication: Paracetamol	1.7	2.8	6.1	-0.7	-1.6	-2.0	-2.5	-1.5	-0.6	-0.9	-2.2	-1.8	-0.8	-2.2
Smoking status: Current	1.7	2.7	5.3	-0.2	-1.2	-2.3	-1.9	-2.0	-0.0	-1.5	-2.3	-2.0	0.6	-1.8
Illnesses of father: High blood pressure	1.7	2.1	5.4	2.0	1.3	1.2	1.7	1.3	0.4	-0.2	0.8	1.3	2.3	1.7
Intelligence (Savage-Jansen 2018)	1.6	4.9	10.4	3.0	2.1	0.9	3.0	1.0	0.6	2.5	2.2	0.6	2.9	3.2
Schizophrenia vs Biploar Disorder	1.6	2.2	5.8	-1.5	-1.2	0.1	-1.2	-1.2	-1.7	-2.4	-0.6	-0.4	-1.7	-2.2
Qualifications: CSEs or equivalent	1.6	2.1	6.0	0.1	-0.4	-0.3	-1.5	-0.0	0.9	-0.7	-2.5	-2.2	-2.2	-1.9
Nervous feelings	1.6	2.9	6.2	-0.5	-1.5	-0.8	-1.9	-0.3	-1.9	-0.7	-2.4	-1.9	-2.5	-2.5
Blood clot in the leg (DVT)	1.6	2.0	7.0	-0.4	-0.2	0.1	-1.8	-0.3	-0.1	0.1	-2.2	-1.9	-2.7	-1.8
Number of children fathered	1.6	1.8	4.9	-1.9	-0.4	-1.4	-1.3	-1.2	-1.1	-2.2	-0.7	0.7	-0.9	-1.7
Shortness of breath walking on level ground	1.6	1.8	5.9	-0.8	-1.2	-2.0	-0.9	-1.3	-0.9	-0.8	-1.7	-0.8	-0.8	-2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	4.9	-1.0	-1.3	-2.1	-0.7	-1.2	-2.2	-0.7	-1.2	-1.3	-1.2	-1.4
Age at last live birth	1.6	2.3	6.1	0.9	1.2	0.4	2.0	1.1	1.7	1.0	1.3	1.5	1.9	2.5
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	6.8	-0.2	0.1	0.2	-1.8	-0.3	-0.0	0.5	-2.3	-1.9	-2.6	-1.9
Chronic bronchitis/emphysema (mother)	1.5	1.8	4.7	1.1	1.9	2.2	1.3	1.4	1.6	0.9	0.9	0.9	-1.1	0.8
Illnesses of siblings: Diabetes	1.5	1.9	7.0	0.1	0.7	0.9	1.0	0.2	1.0	-0.9	1.1	2.3	2.6	1.8
Medication: Aspirin	1.5	1.9	5.6	-1.2	-1.2	-2.2	-1.3	-1.6	-0.7	-2.4	-1.2	-0.7	0.4	-1.0
Current tobacco smoking	1.4	2.4	4.5	-0.1	-0.9	-2.1	-1.9	-2.0	0.5	-1.7	-2.0	-1.6	1.0	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	4.6	1.4	2.1	0.9	1.4	1.1	-0.4	0.5	0.9	2.1	1.1	1.2
Miserableness	1.4	2.5	5.1	-1.4	-1.1	-1.7	-1.7	-2.3	-0.4	-1.5	-1.4	-1.6	-1.5	-2.0
Commuting to job workplace: Public transport	1.4	1.7	4.5	2.1	1.0	1.2	1.4	1.6	-1.4	1.1	-0.8	-0.5	1.3	1.3
Ever smoked	1.4	2.5	9.2	-0.8	-1.8	-3.0	-1.3	-2.3	-0.6	-0.8	-1.8	-1.5	0.9	-0.8
Alzheimer’s Disease (in father)	1.3	1.4	3.8	-0.4	-0.7	-0.9	-1.4	-1.9	-0.1	-1.4	-0.7	-1.1	-1.2	-2.0
Townsend deprivation index at recruitment	1.3	1.9	5.2	-1.4	-1.0	-1.1	-1.8	-2.3	1.4	-1.3	-0.8	-1.4	-0.1	-1.4
Multivitamins +/- minerals	1.3	1.7	4.6	-0.1	-0.5	-2.1	-0.5	-1.4	-1.2	-1.8	-1.0	-1.7	-1.5	-0.9
Had menopause	1.3	1.6	5.1	-1.5	-2.3	-0.8	-1.2	-1.4	-1.6	-0.6	-0.0	-0.4	-1.5	-0.9
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	4.6	-2.2	-1.5	-0.9	-1.3	-2.0	0.3	-0.9	-0.2	-0.6	-1.2	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.5	0.9	1.2	1.1	1.5	0.7	0.8	1.3	1.5	1.4	1.0	1.6
Eye problems/disorders: None of the above	1.3	1.6	7.7	-1.8	1.1	0.4	0.3	-0.5	0.7	-0.7	1.6	2.8	0.3	0.9
Medication: Allopurinol	1.3	1.7	2.8	-0.2	-1.4	-1.2	-1.5	-1.6	-1.4	0.4	-1.7	-1.6	-0.1	-1.6
Handedness (chirality/laterality): Left-handed	1.3	1.5	3.3	-0.9	-0.4	-1.1	-1.2	-0.9	-1.8	-0.8	-1.5	-1.0	-1.6	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	6.5	1.9	-0.6	-0.2	-0.1	0.6	1.0	0.4	-1.1	-2.5	-1.3	-0.8
Medication: Paracetamol	1.3	2.0	4.7	-0.1	-1.2	-1.6	-1.9	-0.9	-0.8	-1.2	-2.2	-1.6	-0.2	-1.9
Chronotype (morning person)	1.2	2.7	12.0	2.1	1.0	2.4	1.8	3.5	-0.9	1.2	-0.2	-0.6	-0.5	0.4
Medication: Co-codamol	1.2	1.4	3.4	0.5	-1.0	-1.5	-0.6	-1.7	-1.8	0.2	-1.2	-1.6	-0.2	-1.1
Stomach or abdominal pain in last month	1.2	1.5	4.1	-0.4	-1.8	0.2	-0.8	-0.5	-2.0	-1.6	-0.6	-1.0	-0.6	-1.8
Qualifications: A levels/AS levels or equivalent	1.2	2.8	6.2	1.2	1.2	0.9	2.2	1.5	1.4	0.9	1.6	1.5	2.4	2.5
Alcohol drinker status: Never	1.2	1.5	2.8	0.7	0.7	1.7	1.3	1.5	1.3	1.3	1.6	1.1	0.4	1.1
Alcohol drinker status: Previous	1.2	1.4	3.9	0.3	0.2	-0.4	-0.9	-1.0	0.5	1.6	-1.2	-2.0	-1.8	-1.3
Bipolar Disorder or Schizophrenia	1.1	2.7	14.3	-2.1	-1.6	-2.1	-1.1	-3.8	-0.7	-0.9	0.5	-0.0	0.3	-0.7
Blood Red Count	1.1	10.5	34.5	1.3	4.0	2.6	3.0	1.2	2.2	0.7	3.9	5.9	2.4	4.5
Sensitivity / hurt feelings	1.1	1.9	5.0	-1.0	-1.1	-0.4	-1.1	-0.5	-2.2	-0.9	-1.9	-1.0	-1.7	-1.9
Hearing difficulty/problems: Yes	1.1	1.6	6.9	-1.3	0.1	0.1	-0.5	-1.0	1.7	-0.9	1.5	2.6	1.4	-0.5
Vitamin and mineral supplements	1.1	1.4	5.3	-0.2	0.2	1.0	0.2	0.2	1.4	0.6	1.0	2.2	2.3	1.0
Hearing difficulty/problems with background noise	1.1	1.7	5.0	-0.5	-1.7	-0.7	-1.8	-1.6	-0.2	-1.9	-0.7	-0.2	0.3	-2.2
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	5.4	-0.5	-1.3	-0.5	-1.2	-0.9	-1.7	-0.7	-1.4	-1.4	-1.4	-2.3
Exposure to tobacco smoke at home	1.1	1.2	4.2	1.4	2.0	1.4	0.8	1.1	1.2	0.3	0.5	0.8	0.6	0.7
Gout (self-reported)	1.1	1.5	3.4	-0.2	-1.7	-1.3	-1.5	-1.5	-0.7	-0.2	-1.8	-1.1	0.4	-1.5
Exposure to tobacco smoke outside home	1.1	1.5	4.4	2.1	0.8	1.2	2.0	1.1	0.3	-0.9	0.9	0.2	1.5	1.2
Number of full sisters	1.1	1.3	3.0	-0.8	-1.2	0.0	-1.6	-0.7	-0.8	0.5	-1.6	-1.7	-1.0	-1.4
Eye problems/disorders: Cataract	1.1	1.3	3.5	1.9	-0.4	-0.1	0.1	1.6	1.0	1.0	-1.4	-1.8	0.8	0.7
Mother’s age at death	1.1	1.4	6.9	-0.8	0.2	0.2	1.0	0.5	0.2	0.1	2.2	2.6	0.5	1.3
Number of operations (self-reported)	1.1	1.7	4.8	2.2	-0.2	1.3	0.3	0.7	-0.7	1.8	-0.9	-2.2	-1.4	-0.7
Average weekly beer plus cider intake	1.1	1.6	3.7	-0.3	-0.9	-1.9	-1.0	-1.9	-1.4	-1.4	-1.0	-0.6	-0.3	-1.6
Verbal and Numeric Reasoning (VNR)	1.0	2.4	5.3	2.2	1.3	0.2	2.1	0.4	-0.2	2.3	1.8	-0.0	1.6	2.2
Medication: Atenolol	1.0	1.2	5.7	-0.3	-0.7	-1.3	0.4	-1.0	-0.5	-1.7	0.6	0.6	2.4	0.8
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	7.2	-0.9	-0.6	-0.2	-1.2	-0.4	-0.9	-1.2	-1.4	-0.8	-2.7	-1.5
Prospective memory result	1.0	1.3	4.6	-0.9	-0.5	-1.4	-1.2	-0.9	-0.1	-1.1	-0.8	-0.2	-1.4	-2.1
Birth weight of first child	1.0	1.8	5.9	-0.9	-1.3	-2.4	-1.3	-1.6	-1.4	-0.0	-1.2	-1.5	-0.3	-1.2
Comparative height size at age 10	1.0	5.2	15.8	-1.8	-2.3	-1.9	-2.7	-1.8	-1.5	0.3	-1.8	-2.6	-2.5	-4.0
Eye problems/disorders: Glaucoma	1.0	1.1	3.0	1.6	0.6	1.3	1.7	1.3	-0.0	-0.1	1.3	0.6	0.3	1.0
Pain type(s) experienced in last month: Hip pain	1.0	1.2	3.2	-0.1	-1.8	-1.5	-1.1	-1.0	-1.0	0.1	-1.3	-0.8	-0.2	-1.6
Pain experienced in last month	1.0	1.7	4.8	0.6	2.1	-0.5	1.3	0.4	1.2	0.6	0.7	1.2	1.8	2.2
Worry (Nagel 2018)	0.9	1.8	5.5	0.3	-0.9	0.5	-1.0	0.9	-1.1	0.1	-2.0	-1.8	-2.4	-1.8
Prostate Cancer	0.9	1.3	3.3	-1.8	-0.4	-0.9	-1.2	-1.5	-0.9	-1.3	-0.0	1.0	-0.8	-1.3
Mean Putamen Volume	0.9	1.0	3.0	1.2	0.7	0.8	0.9	1.6	-0.9	1.7	-0.8	-0.0	0.2	0.9
Fasting Glucose	0.9	1.1	3.3	0.2	0.6	0.9	1.4	0.6	-0.6	-1.5	1.5	1.8	-0.1	0.7
Severe depression (siblings)	0.9	1.0	4.5	0.4	-0.7	0.3	-0.4	0.0	-0.5	1.4	-1.1	-2.1	-1.3	-1.0
Age when periods started (menarche)	0.9	2.2	7.8	1.7	1.5	1.3	2.4	2.8	-1.1	0.7	0.7	0.6	0.2	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	8.4	0.6	0.7	1.4	1.7	0.9	0.1	1.2	2.9	1.7	0.7	2.0
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	4.7	-0.9	-0.9	-0.4	-0.7	-0.1	-1.9	0.6	-0.9	-1.0	-2.2	-1.7
Glaucoma (self-reported)	0.9	1.0	2.0	1.0	0.6	1.4	1.3	0.9	1.0	-0.2	1.4	0.9	0.7	1.1
Medication for pain relief, constipation, heartburn	0.9	1.5	5.2	0.0	1.0	1.0	1.6	0.3	-2.3	1.1	1.4	1.6	0.2	1.2
Migraine (self-reported)	0.9	1.1	3.4	1.8	1.3	0.5	0.6	1.7	1.3	-0.2	-1.0	-0.6	0.5	0.7
Breast Cancer	0.8	2.0	6.5	1.5	0.6	1.8	1.1	2.0	0.5	1.0	0.2	-2.6	-0.2	1.7
Primary Biliary Cirrhosis	0.8	1.2	3.1	0.8	0.7	1.3	1.8	1.3	-0.2	0.0	0.9	1.1	1.0	1.6
Lung FEV1/FVC ratio	0.8	4.3	7.9	-1.5	-1.9	-1.8	-2.8	-2.5	-1.0	0.1	-1.8	-2.7	-2.3	-2.8
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	4.1	2.0	1.3	0.9	1.1	0.6	0.1	-0.4	0.5	0.1	0.9	0.5
Diabetes (mother)	0.8	1.1	5.6	1.1	0.2	1.5	-0.1	0.8	-2.4	-0.8	-1.0	0.0	-0.0	-0.6
Impedance of leg (left)	0.8	3.7	12.0	0.8	-0.8	1.6	0.7	2.5	-3.3	1.6	-1.2	-1.8	-3.5	-0.4
Past tobacco smoking	0.8	1.5	7.3	0.9	1.4	2.7	0.9	1.6	0.3	0.0	1.0	1.1	-0.8	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	10.4	0.3	-0.2	-0.1	-0.4	0.5	3.2	-0.3	-0.6	-0.2	0.2	-0.1
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.2	-1.4	-0.1	-1.3	-1.0	-0.4	1.4	-1.5	-0.0	0.6	-0.6	-1.0
Leg pain on walking	0.8	1.1	2.6	-0.1	-1.1	-0.2	-0.8	-0.6	-0.4	-1.3	-1.1	-1.6	-1.3	-1.3
Wears glasses or contact lenses	0.8	0.9	2.5	-0.2	-0.9	-0.8	0.5	-1.1	-1.6	-1.5	0.6	-0.7	0.7	0.7
High cholesterol (Self-reported)	0.8	1.4	3.7	0.4	1.3	-0.1	0.8	0.5	1.3	-0.9	1.1	1.9	1.6	1.9
Medication: Lisinopril	0.8	1.0	8.6	0.6	-0.3	-0.3	0.4	0.1	0.0	-0.5	0.4	0.4	2.9	1.3
Reaction Time	0.7	1.3	5.5	-1.5	0.7	-0.7	-0.6	-1.4	0.3	-1.7	-0.6	2.4	0.5	0.1
HDL Cholesterol	0.7	1.2	3.2	1.8	0.6	0.5	1.0	1.4	-1.3	1.2	-0.8	-1.5	0.3	0.8
Respiratory disease	0.7	1.6	4.8	0.1	-0.7	-0.6	-0.8	-0.0	-2.0	0.5	-1.4	-1.7	-1.6	-2.2
Ever used hormone-replacement therapy (HRT)	0.7	0.8	2.0	0.5	-1.4	-0.9	-0.8	-1.3	-0.4	0.2	-1.2	-1.3	-0.0	-0.8
Supplements: Zinc	0.7	0.8	2.7	-0.4	-0.6	-0.8	-1.1	-0.6	-0.0	-0.3	-0.8	-1.1	-1.7	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	6.2	0.4	0.6	0.8	1.4	0.5	0.5	0.7	2.5	1.6	0.5	1.8
Alcohol usually taken with meals	0.7	1.2	4.1	0.1	0.7	1.8	1.2	2.0	-0.5	0.8	0.2	0.1	-0.1	1.8
Alcohol intake versus 10 years previously	0.7	1.0	4.7	2.2	1.2	0.3	0.5	1.4	1.1	1.1	0.3	0.1	-0.7	-0.2
Number of live births	0.7	0.9	5.9	0.2	-0.6	0.0	-0.7	-0.8	-2.4	-0.2	-0.2	-0.1	-0.8	-1.5
Lung cancer (father)	0.7	0.8	2.9	1.0	1.0	0.4	0.9	0.9	1.1	1.7	0.8	0.1	-0.4	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	2.1	-0.0	0.1	-0.9	-1.2	-1.5	-0.4	-0.6	-1.4	-1.5	-1.2	-1.3
Medication: Ibuprofen	0.7	0.8	8.1	0.4	0.2	-0.2	-0.2	0.6	2.9	-0.3	-0.6	-0.2	-0.0	-0.2
Mean time to correctly identify matches	0.7	1.3	8.0	-1.8	0.6	-0.7	-0.5	-1.4	-0.1	-0.8	0.1	2.8	0.1	0.1
Arm predicted mass (right)	0.7	3.5	9.4	-1.6	-2.1	-2.0	-2.3	-2.0	-1.3	-1.4	-1.6	-1.2	-0.9	-3.1
Alcohol intake frequency.	0.7	1.7	6.9	1.2	0.5	0.4	-0.3	0.5	0.6	2.3	-0.4	-1.2	-2.6	-1.4
Knee pain experienced in last month	0.7	1.1	3.6	-0.3	-1.9	-0.1	-1.0	-0.0	-0.6	-0.4	-0.6	-0.6	-1.5	-1.9
Mineral and other dietary supplements	0.7	0.9	3.0	-0.0	0.5	1.6	0.5	-0.0	0.9	-0.3	0.8	1.2	1.7	1.1
Osteoarthritis (self-reported)	0.7	1.0	4.2	-0.9	-1.0	-1.4	-0.9	-2.1	0.7	-0.7	0.2	0.5	0.7	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	3.9	0.8	1.5	1.5	1.3	1.0	-1.4	-0.3	1.8	2.0	-0.4	0.2
Supplements: Fish oil (including cod liver oil)	0.7	1.0	3.2	-0.1	-0.2	-1.7	-0.5	-0.1	-1.2	0.2	-0.3	-0.7	-1.8	-1.4
Medication: Bendroflumethiazide	0.7	1.0	3.4	0.0	0.2	-0.9	-0.4	-0.0	1.4	-1.3	-0.5	1.3	1.8	1.1
Diastolic blood pressure, automated reading	0.7	2.2	10.4	1.3	1.5	-0.2	1.3	0.8	1.5	-0.8	0.6	0.8	3.2	2.0
Supplements: Calcium	0.7	0.7	1.8	-0.3	-0.4	-1.3	-0.4	-0.4	-0.8	0.5	-1.0	-1.3	-1.4	-0.6
Basal cell carcinoma (self-reported)	0.7	0.8	2.7	0.6	0.7	0.2	1.0	-0.5	0.2	-0.3	1.6	1.1	1.1	1.1
Bipolar Disorder (2018)	0.6	1.0	3.0	-0.0	0.3	-1.5	-0.0	-1.4	1.7	0.4	1.0	0.6	1.2	0.7
Alzheimer’s Disease (in mother)	0.6	0.7	1.7	-0.1	0.1	1.1	0.8	0.3	1.1	0.5	0.6	1.1	1.2	1.3
Bipolar Disorder (2011)	0.6	0.6	3.1	-0.6	-0.7	-1.2	-0.4	-1.7	-0.6	0.2	0.8	0.4	0.2	-0.1
Body Mass Index (BMI) (2010)	0.6	0.8	1.7	-0.6	-0.9	-1.2	-1.0	-0.9	0.4	-0.7	-1.3	-0.6	0.7	-0.8
Coronary Artery Disease (CAD)	0.6	0.8	2.4	-0.0	0.8	0.1	1.2	1.2	0.8	1.5	0.6	-0.6	-0.5	0.9
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.4	-0.1	-0.0	1.5	1.1	0.3	-0.1	1.2	0.9	0.5	0.1	1.2
Height	0.6	11.9	27.4	-2.6	-3.8	-2.6	-2.8	-0.9	-3.9	-2.3	-3.2	-4.3	-4.1	-5.2
Waist Hip Ratio (WHR)	0.6	2.7	9.6	-0.7	-0.1	-0.2	-1.9	-0.6	-2.3	-1.9	-3.1	-1.9	-0.8	-1.7
Cardiovascular Disease	0.6	1.9	5.7	2.1	1.1	-0.4	0.8	0.9	2.3	0.6	-0.0	-0.2	2.4	1.6
Lung FVC	0.6	3.0	14.7	-0.5	1.3	0.5	1.5	0.8	-0.1	-1.1	3.0	3.8	1.0	1.4
Medication for hormone replacement therapy	0.6	0.7	3.0	0.8	-0.6	-0.8	0.6	-0.3	-0.8	1.1	0.0	-1.7	-0.8	-0.0
Maternal smoking around birth	0.6	0.8	3.6	-0.3	1.1	0.1	0.2	-0.9	1.9	-0.3	1.0	0.7	0.8	1.0
Serious illness, injury or assault to yourself	0.6	0.7	1.8	-0.0	-1.3	-0.2	-1.0	-0.2	1.0	-1.3	-0.8	-0.9	0.4	-0.5
Waist circumference	0.6	2.3	5.2	-0.8	-0.7	-1.2	-2.1	-2.3	0.5	-2.2	-1.8	0.1	1.9	-1.1
Mouth/teeth dental problems	0.6	1.0	3.8	1.2	0.3	0.9	1.1	0.8	0.9	1.9	0.8	-0.4	-0.2	0.9
Pain all over the body in last month	0.6	0.6	2.8	0.2	0.1	0.2	-0.8	0.4	0.3	-0.8	-0.9	-0.7	-1.7	-1.1
Fluid intelligence score	0.6	1.2	3.5	1.9	0.7	-0.2	1.5	0.2	-0.3	1.0	1.0	-0.4	1.2	1.7
Weight	0.6	2.9	6.8	-1.2	-1.5	-2.1	-2.2	-2.6	0.7	-2.0	-1.4	-0.6	0.7	-2.2
Arm fat mass (right)	0.6	2.4	6.6	-0.7	-0.7	-1.7	-2.0	-2.6	1.5	-2.0	-1.2	-0.1	1.7	-1.3
Forced vital capacity (FVC), Best measure	0.6	2.0	5.4	0.7	1.7	1.3	1.9	2.1	-0.2	-0.1	1.8	2.3	-0.8	0.2
Arm fat-free mass (right)	0.6	2.9	8.4	-1.5	-2.0	-1.7	-2.1	-1.8	-1.1	-1.2	-1.4	-1.2	-0.9	-2.9
Comparative body size at age 10	0.6	1.6	11.6	-0.5	0.1	-0.1	0.2	-0.8	3.4	0.6	1.4	0.7	1.2	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	4.5	-1.0	-0.7	-0.5	-0.2	-2.1	-0.2	-0.5	1.1	1.0	0.1	-0.1
Leg fat mass (right)	0.6	2.2	6.1	-1.1	-1.1	-1.3	-2.2	-2.5	0.9	-1.7	-1.4	-0.1	0.7	-1.6
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.0	0.2	0.4	1.3	0.6	0.8	-1.3	1.4	0.3	0.6	-0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.8	1.6	0.0	0.4	0.4	1.6	0.8	1.3	-0.9	-1.9	-0.2	-0.3
Arm fat percentage (left)	0.6	2.3	5.7	-0.3	-0.2	-1.3	-1.6	-2.3	2.4	-1.9	-0.9	0.3	2.2	-0.4
Long-standing illness, disability or infirmity	0.6	0.9	2.4	-0.7	-1.1	-0.3	-1.2	-1.4	-0.0	-1.6	-0.9	-0.7	0.7	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.2	-0.5	-1.1	1.0	-0.1	0.3	0.0	-0.4	0.1	-1.4	-1.8	-0.4
Arm fat mass (left)	0.6	2.6	7.4	-0.8	-0.8	-1.8	-2.1	-2.7	1.5	-2.0	-1.2	-0.1	1.5	-1.4
Arm fat-free mass (left)	0.6	3.0	7.9	-1.5	-1.9	-1.8	-2.1	-2.2	-0.9	-1.2	-1.3	-1.2	-0.8	-2.8
HbA1C	0.5	0.6	1.5	1.1	1.0	-0.1	-0.0	0.8	0.7	-1.2	-0.2	-0.8	0.9	0.2
Lupus	0.5	0.8	2.5	0.8	0.5	1.6	1.1	1.0	-0.3	1.0	1.1	-0.0	-0.2	0.7
Triglycerides	0.5	0.8	5.6	-0.4	0.3	-0.6	-0.2	-0.8	2.4	0.3	0.8	0.5	0.7	0.5
BMI	0.5	3.0	13.0	0.1	1.0	-0.8	-1.4	-2.1	3.6	-1.6	-0.6	1.2	2.9	0.1
Number of treatments/medications taken	0.5	1.0	3.3	1.3	0.2	-1.8	-0.4	-0.2	0.8	-0.9	-1.1	-0.9	1.4	-0.2
Average weekly spirits intake	0.5	0.6	3.5	0.5	-0.2	-1.0	0.5	-0.9	-0.5	-0.6	0.3	0.2	1.9	0.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.9	-0.5	0.3	0.2	-1.2	-0.8	0.2	-1.4	-1.2	0.0	-0.7	-1.1
Ever had hysterectomy (womb removed)	0.5	0.6	2.2	1.5	0.6	0.2	0.8	0.0	0.7	1.4	0.2	-0.7	0.7	0.5
Impedance of leg (right)	0.5	2.6	8.6	0.3	-0.8	1.6	0.6	2.2	-2.7	1.5	-0.8	-1.1	-2.9	-0.2
Leg fat-free mass (left)	0.5	2.8	6.1	-1.4	-1.3	-2.4	-2.0	-2.5	0.6	-1.6	-1.2	-1.1	0.6	-2.3
Body mass index (BMI)	0.5	2.3	7.5	-0.6	-0.4	-1.3	-1.8	-2.7	1.9	-1.8	-0.7	0.6	2.1	-0.9
Leg predicted mass (left)	0.5	2.8	6.1	-1.4	-1.3	-2.3	-2.0	-2.5	0.5	-1.6	-1.3	-1.1	0.7	-2.3
Trunk fat mass	0.5	2.2	5.8	-1.0	-1.0	-1.7	-1.9	-2.4	0.8	-2.1	-1.2	0.1	1.0	-1.5
Financial difficulties in last 2 years	0.5	0.7	2.6	0.6	0.6	-0.5	0.7	0.1	1.4	0.1	0.3	-0.4	1.6	1.0
Medication: Ramipril	0.5	0.7	2.0	1.0	1.4	0.7	0.3	0.2	1.2	0.3	-0.3	0.2	1.1	0.8
Arm fat percentage (right)	0.5	2.1	5.7	-0.2	0.1	-1.1	-1.5	-2.2	2.4	-1.7	-0.8	0.3	2.3	-0.2
Trunk fat-free mass	0.5	2.6	8.6	-1.2	-1.8	-1.7	-1.9	-1.5	-0.7	-0.8	-1.3	-1.8	-1.1	-2.9
Worrier / anxious feelings	0.5	1.0	2.1	-0.2	0.1	1.4	1.1	1.4	-1.3	0.7	1.0	0.9	-0.9	0.7
Trunk predicted mass	0.5	2.8	8.8	-1.2	-1.8	-1.7	-2.0	-1.5	-0.7	-0.8	-1.4	-1.8	-1.1	-3.0
Standing height	0.5	4.8	10.9	-1.3	-2.7	-1.9	-1.2	-0.3	-2.7	-0.5	-1.7	-2.9	-3.0	-3.3
Length of working week for main job	0.5	0.5	2.0	0.8	-0.7	-0.0	-0.5	-0.3	1.2	-0.1	-0.9	-1.4	0.2	-0.1
Breastfed as a baby	0.5	0.6	1.3	-0.3	-0.7	-0.7	-0.8	-0.5	-0.3	-0.5	-0.4	-1.1	-1.1	-1.1
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.3	-0.4	-1.3	-0.7	-0.3	-0.7	-0.9	1.5	-0.6	-1.8	-0.3	-0.2
Medication: Amlodipine	0.5	0.7	2.9	0.4	1.7	-0.4	0.2	-1.1	0.9	0.5	0.3	0.5	1.2	0.3
Leg fat percentage (right)	0.5	1.9	5.2	-1.4	-1.1	-0.8	-2.1	-2.3	0.8	-1.7	-1.3	0.2	0.4	-1.2
Number of full brothers	0.5	0.6	1.7	0.7	1.0	-0.7	0.9	0.4	1.3	-0.2	0.7	0.5	0.8	0.7
Wheeze or whistling in the chest in last year	0.5	0.8	2.1	-0.2	-0.6	-1.1	-0.8	-0.7	-1.0	-0.9	-1.0	-0.7	-1.0	-1.5
Medication: Seretide 50 evohaler	0.5	0.6	1.5	-0.3	-0.5	-1.0	-0.8	-0.6	-0.9	-0.4	-1.2	-0.7	-0.2	-0.9
Heart disease (mother)	0.5	0.7	4.6	-1.2	-0.7	-0.1	-0.4	-0.4	0.1	-2.2	-0.3	0.1	0.3	-0.2
Whole body fat mass	0.5	2.2	5.9	-0.9	-1.1	-1.7	-2.0	-2.4	1.1	-2.0	-1.2	-0.0	0.9	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.7	0.5	-0.0	-0.6	-0.7	0.2	-0.9	-0.5	-0.8	-1.2	-0.8	-1.3
Whole body fat-free mass	0.5	2.7	7.6	-1.3	-1.7	-2.0	-2.0	-2.0	-0.4	-1.2	-1.3	-1.5	-0.4	-2.8
Leg fat-free mass (right)	0.5	2.5	5.3	-1.1	-1.2	-2.3	-1.8	-2.3	0.2	-1.5	-1.2	-1.3	0.4	-2.3
Whole body water mass	0.5	2.8	7.7	-1.3	-1.6	-2.1	-2.0	-2.1	-0.3	-1.2	-1.4	-1.5	-0.4	-2.8
Leg predicted mass (right)	0.5	2.8	5.9	-1.2	-1.4	-2.4	-1.8	-2.4	0.0	-1.5	-1.3	-1.4	0.4	-2.4
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.2	-0.9	0.7	-0.3	-0.2	-0.1	-0.0	-1.0	0.4	1.2	1.5	0.5
Basal metabolic rate	0.5	2.7	7.1	-1.2	-1.6	-2.0	-2.1	-2.2	-0.1	-1.4	-1.4	-1.4	-0.2	-2.7
Leg fat mass (left)	0.5	2.0	5.6	-1.0	-1.1	-1.3	-2.1	-2.4	0.7	-1.8	-1.3	-0.2	0.6	-1.6
Arm predicted mass (left)	0.5	2.5	7.5	-1.3	-1.7	-1.7	-2.0	-2.0	-0.7	-1.1	-1.1	-1.1	-0.8	-2.7
Alzheimer’s Disease (including proxy)	0.4	0.6	2.7	-1.3	-0.5	-0.3	-0.7	-1.6	0.1	-0.9	-0.3	0.2	0.0	-0.6
Blood Eosinophil Count	0.4	3.3	6.2	-2.4	-1.6	-1.7	-1.6	-1.9	-1.5	-2.5	-1.2	0.6	-1.6	-2.3
Allergy or Eczema	0.4	1.1	4.1	-0.1	1.1	1.1	0.9	0.8	1.4	-0.4	1.2	2.0	-0.3	0.5
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.6	1.6	1.2	1.2	0.2	0.8	0.6	0.0	-1.0	-0.1	0.6	-0.2
Hand grip strength (left)	0.4	0.9	4.2	-0.0	0.2	-0.8	0.4	0.2	-0.6	1.6	0.5	-0.4	-2.1	-1.3
Pack years adult smoking proportion	0.4	0.7	2.5	1.6	0.9	0.8	0.3	0.4	1.0	0.0	-1.1	-0.7	0.7	0.0
Trunk fat percentage	0.4	1.7	4.8	-0.7	-0.7	-1.3	-1.6	-2.2	1.1	-1.9	-0.9	0.6	1.4	-0.8
Hand grip strength (right)	0.4	1.0	5.6	0.8	0.7	0.2	1.2	1.0	0.1	2.4	1.1	-0.0	-0.8	-0.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.5	-0.0	-0.9	-0.4	-0.7	-1.0	-0.7	-0.0	-0.5	-0.3	-0.2	-1.2
High blood pressure	0.4	1.0	6.7	1.4	0.4	-1.0	0.1	0.2	0.3	-0.5	-0.7	-0.0	2.6	0.6
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	4.3	-0.0	-0.0	2.1	0.4	-0.2	-0.7	0.0	0.6	0.5	-0.5	0.1
Medication: Levothyroxine sodium	0.4	0.7	1.9	0.0	-0.8	-1.3	-0.1	-1.0	-0.7	1.3	-0.6	-1.4	0.1	0.1
Father’s age at death	0.4	0.5	2.4	0.1	-0.1	1.6	0.1	0.8	-1.2	0.7	-0.5	0.2	0.1	0.3
Pulse wave reflection index	0.4	0.5	2.4	0.0	0.4	-0.1	-0.0	-0.7	0.7	-0.9	0.8	0.3	1.5	0.7
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.2	0.7	0.6	-0.5	1.1	0.6	-0.8	-0.9	0.9	0.7	0.5	0.2
Birth weight	0.4	0.8	3.9	0.5	0.6	0.6	0.9	0.2	-0.3	-0.4	0.3	-0.1	2.0	1.6
Body fat percentage	0.4	1.5	4.4	-0.7	-0.6	-1.1	-1.6	-2.1	1.2	-1.8	-0.9	0.5	1.2	-0.7
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.5	-0.9	0.0	-0.4	-0.8	-0.3	1.2	-1.0	-0.9	0.5	0.5	-0.2
Medication: Blood pressure	0.4	0.7	4.4	1.0	0.3	-0.5	0.2	-0.8	0.7	-0.8	0.4	0.4	2.1	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.1	-0.4	-0.9	1.4	0.3	1.0	-0.3	0.3	0.1	0.0	-0.8	0.2
Hypertension (Self-reported)	0.4	1.0	6.0	0.9	0.3	-1.3	-0.4	-0.3	0.6	-1.0	-0.8	0.0	2.5	0.3
Qualifications: nursing, teaching	0.4	0.6	2.0	0.2	-0.2	-1.2	0.4	-0.3	0.8	0.9	0.1	-0.2	1.4	1.0
Medication for cholesterol	0.4	0.6	1.6	-1.1	-0.3	0.7	-0.7	0.1	1.2	-0.5	-0.1	0.0	-1.3	-1.0
Breast cancer (self-reported)	0.4	0.5	2.6	0.5	1.1	0.7	0.3	0.2	0.2	0.3	0.6	1.6	0.6	-0.4
Asthma (self-reported)	0.4	0.7	2.2	-0.2	-0.8	-1.0	-0.6	-0.2	-0.8	0.0	-0.7	-1.0	-1.3	-1.5
Number of self-reported non-cancer illnesses	0.4	0.8	2.2	0.3	-0.4	-1.5	-0.9	-1.0	0.3	-0.3	-1.4	-1.0	0.8	-0.6
Average weekly champagne plus white wine intake	0.4	0.5	1.9	-0.2	-1.4	0.7	-0.3	0.8	-0.6	0.3	-0.7	-1.2	-0.7	-0.1
Medication: Blood pressure	0.4	0.8	3.0	-0.0	0.1	-1.7	-0.7	-0.8	-0.8	-0.3	-1.1	0.4	1.7	0.3
Leg fat percentage (left)	0.4	1.5	4.2	-1.0	-1.0	-0.8	-1.9	-2.1	0.6	-1.6	-1.3	0.0	0.2	-1.2
Ever had prostate specific antigen (PSA) test	0.4	0.5	3.1	-0.1	0.3	0.1	-0.4	0.0	1.8	0.3	0.8	1.0	-0.4	-0.1
Unable to work because of sickness or disability	0.4	0.5	3.0	0.6	0.2	-0.2	0.4	-0.5	-0.6	-1.7	0.7	0.6	0.2	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.4	0.9	0.5	0.9	1.2	0.7	0.5	0.5	0.8	0.5	0.2	0.6
Heart disease (siblings)	0.4	0.5	1.8	-0.5	0.1	0.6	0.4	-0.6	-0.5	-0.8	1.1	1.3	-0.0	-0.1
Ovarian Cancer	0.3	0.4	0.7	-0.4	-0.8	0.4	0.6	0.7	-0.7	0.7	0.1	-0.8	0.1	0.7
Rheumatoid Arthritis	0.3	0.4	1.4	-0.7	-0.3	-0.4	-0.8	-1.2	0.1	0.3	0.3	0.3	-0.4	-1.1
Ulcerative Colitis	0.3	0.4	1.1	0.0	0.4	0.8	-0.0	0.9	-0.0	-1.1	-0.6	0.8	0.6	0.3
Blood Platelet Count	0.3	3.0	14.7	-1.6	-1.1	-1.0	-1.4	-2.0	-3.8	0.5	-2.0	-0.3	-0.1	-1.9
Medication: Metformin	0.3	0.5	2.2	1.5	0.7	0.8	0.2	0.7	0.6	-0.7	-0.2	-0.0	0.6	-0.3
Average weekly fortified wine intake	0.3	0.3	1.0	-0.4	-0.2	0.2	-0.7	-0.6	0.2	0.9	0.0	-1.0	-0.6	-0.2
Hayfever, allergic rhinitis or eczema	0.3	0.8	3.2	0.1	0.8	0.6	0.8	0.9	1.3	-0.2	0.8	1.8	0.1	0.5
Supplements: Glucosamine	0.3	0.4	1.1	0.4	-0.8	0.0	-0.2	0.1	-0.2	0.8	-0.3	-1.1	-1.0	-0.7
Sitting height	0.3	2.1	7.2	-2.1	-1.6	-2.7	-0.4	-1.3	-1.4	-1.5	0.4	0.4	-0.3	-1.5
Forced vital capacity (FVC)	0.3	1.2	4.8	0.0	0.5	1.0	1.4	2.2	-0.4	0.1	1.3	1.6	-1.1	-0.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.0	-0.6	-0.1	-1.0	-0.9	-0.1	0.4	-0.1	-0.7	0.1	-0.8	-0.9
Medication: Simvastatin	0.3	0.4	1.1	-0.6	-1.0	-0.4	-0.2	-0.6	1.1	-0.6	0.2	0.1	0.8	0.8
Illnesses of siblings	0.3	0.4	1.8	0.4	0.5	-0.2	-0.4	0.2	0.6	-0.2	-0.8	-1.3	-0.6	-0.3
Hip circumference	0.3	1.2	3.2	-0.1	-0.9	-1.0	-1.3	-1.4	1.8	-0.8	-0.8	-0.0	1.8	-0.6
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.7	-0.6	0.0	0.9	0.7	1.5	-0.1	-0.1	1.1	1.2	-1.6	-0.6
Pulse rate	0.3	0.6	3.8	0.5	-0.0	0.7	0.4	-0.1	1.1	1.9	0.1	0.5	0.6	-0.0
Mouth/teeth dental problems: Dentures	0.3	0.4	1.5	-0.1	0.0	-0.4	-0.0	0.0	-0.9	-1.1	0.5	1.2	0.9	-0.1
Asthma	0.3	0.5	1.6	-0.0	-0.7	-0.7	-0.5	-0.0	-0.5	0.2	-0.6	-1.1	-1.1	-1.3
Medication: Lansoprazole	0.3	0.4	2.5	0.6	-0.1	-0.5	-0.5	-0.2	-0.2	0.1	-0.6	-1.6	0.2	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	2.8	-0.0	0.9	1.0	1.2	1.2	-0.7	-0.3	1.4	1.7	-1.1	-0.2
Hair/balding pattern: Pattern 4	0.3	0.8	2.2	1.1	-0.0	1.5	0.9	1.4	1.4	0.4	0.7	-0.3	-0.1	0.5
Peak expiratory flow (PEF)	0.3	0.6	1.7	-1.1	-0.1	-0.7	0.6	0.3	0.4	-1.3	1.0	1.1	-0.8	-0.1
Worry too long after embarrassment	0.3	0.5	1.5	-1.0	-1.2	0.3	-0.5	-0.5	-1.2	-0.2	-0.8	-0.2	-0.9	-0.4
Qualifications: College or University degree	0.3	1.0	2.7	1.0	0.4	-0.3	1.0	0.5	-0.4	1.5	-0.3	-1.7	1.1	1.5
Emphysema/chronic bronchitis	0.3	0.4	2.6	0.1	-0.0	0.1	0.0	-0.5	-1.6	-0.6	-0.1	0.5	0.3	-0.5
Pulse rate, automated reading	0.3	1.0	3.3	1.1	0.5	0.4	-0.5	-1.2	1.6	1.8	0.3	0.5	0.3	-1.0
Suffer from ‘nerves’	0.3	0.4	1.0	0.9	0.7	0.9	0.4	1.0	0.8	0.6	0.0	-0.1	-0.5	-0.2
Family relationship satisfaction	0.3	0.4	1.4	0.1	0.7	0.1	-0.1	-0.6	-1.2	-1.0	-0.4	0.9	0.1	-0.7
Average weekly red wine intake	0.3	0.4	1.1	-1.0	-1.0	-0.6	-0.2	-0.5	0.0	-0.9	-0.1	-0.3	1.0	0.1
Ever had bowel cancer screening	0.3	0.3	1.0	0.3	0.1	1.0	0.5	0.2	-0.0	0.4	1.0	0.8	-0.3	0.1
Diabetes diagnosed by doctor	0.3	0.5	1.3	1.1	0.8	0.8	0.1	0.4	0.2	-0.7	-0.7	0.3	1.2	-0.1
Ever taken oral contraceptive pill	0.3	0.3	1.0	0.2	-0.3	0.5	-0.1	0.7	1.0	0.5	-0.6	-1.0	0.2	0.1
Hearing aid user	0.3	0.3	1.1	-0.4	-0.0	-0.7	-0.4	-0.9	-0.7	-1.0	0.4	0.0	0.1	-0.4
Ever depressed for a whole week	0.3	0.4	1.3	-0.8	-0.1	-0.1	-0.4	-0.8	0.8	1.1	0.3	-0.5	-0.6	-0.7
Vascular/heart problems diagnosed by doctor	0.3	0.9	6.2	-0.9	-0.3	0.9	-0.2	0.1	-0.2	0.8	0.5	-0.1	-2.5	-0.7
Pack years of smoking	0.3	0.5	1.5	1.2	0.8	0.8	0.5	0.4	1.0	-0.1	-0.5	-0.1	0.9	0.4
Impedance of whole body	0.3	1.5	4.7	0.6	-0.6	0.9	0.8	1.7	-2.2	0.8	-0.7	-1.3	-2.1	0.1
Major Depression (MDD)	0.2	0.3	0.9	-0.0	-0.0	0.3	-0.2	-0.3	0.9	-0.6	0.6	0.1	-0.7	-0.5
Crohns Disease (2012)	0.2	0.4	1.8	0.3	-0.0	0.1	0.6	0.4	0.1	0.2	1.4	0.7	0.9	0.7
Heel T-Score	0.2	1.7	7.0	-1.3	-0.1	1.4	0.3	0.1	-0.3	0.5	2.6	2.5	-0.8	0.8
Hypothyroidism (self reported)	0.2	0.4	2.0	0.2	-1.0	-0.2	-0.3	-0.4	0.0	0.9	-0.5	-1.4	-0.1	-0.1
Tanning	0.2	2.9	8.2	-2.7	-2.9	-1.0	-0.4	-1.5	-1.6	-0.3	2.3	1.8	-0.3	-1.1
Taking other prescription medications	0.2	0.3	1.3	1.1	-0.5	-0.2	-0.0	0.5	-1.1	0.2	-0.6	-0.4	-0.0	-0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	-0.9	-0.5	-0.0	0.3	-0.2	-0.8	0.5	0.4	-0.1	-0.3	0.3
High blood pressure (mother)	0.2	0.3	1.9	0.3	0.2	-0.3	0.6	0.5	0.1	0.4	-0.3	0.5	1.4	0.7
Number of incorrect matches in round	0.2	0.3	1.0	-0.0	0.2	0.3	0.5	0.2	0.2	0.1	0.1	0.9	0.7	1.0
Hair/balding pattern: Pattern 2	0.2	0.2	0.6	0.6	-0.2	0.4	0.5	0.7	-0.1	0.5	0.8	-0.0	-0.1	0.5
Diabetes (self-reported)	0.2	0.3	0.7	0.8	0.7	0.6	-0.3	-0.2	0.8	-0.6	-0.4	0.3	0.7	-0.7
Impedance of arm (right)	0.2	1.0	2.8	1.1	0.7	0.9	1.2	1.7	-0.1	0.9	-0.2	-1.2	-0.7	1.0
Time employed in main current job	0.2	0.2	0.6	-0.0	-0.1	0.1	0.7	0.6	-0.1	-0.1	0.6	0.8	0.4	0.7
Hair/balding pattern: Pattern 3	0.2	0.3	1.7	0.1	-0.2	-1.3	-0.4	-0.3	-0.1	0.5	-0.8	-0.2	-0.1	-0.8
Noisy workplace	0.2	0.3	0.5	-0.5	-0.2	0.2	-0.7	0.3	0.1	0.7	-0.7	-0.6	-0.4	-0.7
Depression (self-reported)	0.2	0.2	0.6	0.7	0.2	-0.1	0.8	0.3	-0.2	-0.5	0.4	-0.1	0.5	0.6
Illnesses of mother	0.2	0.3	1.3	0.3	0.4	-0.5	0.3	-0.3	0.1	-0.0	1.1	0.7	0.7	0.3
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	0.7	0.3	0.1	-0.2	-0.1	0.5	0.5	-0.6	-0.7	0.5	-0.2
Impedance of arm (left)	0.2	0.7	2.0	0.8	0.1	0.7	0.9	1.4	-0.3	0.8	-0.5	-1.4	-0.9	0.7
Headache pain in last month	0.2	0.3	1.1	0.4	-1.1	0.3	-0.3	0.4	1.0	-0.2	-0.3	-0.7	0.4	-0.4
High blood pressure (siblings)	0.2	0.3	0.9	-0.3	-0.8	-0.9	-0.1	-0.4	-0.4	-0.2	-0.4	0.5	1.0	-0.1
Pulse wave peak to peak time	0.2	0.2	0.6	-0.8	-0.5	-0.1	0.1	0.2	-0.6	-0.5	0.4	0.5	-0.7	0.0
Angina (self-reported)	0.2	0.2	0.7	0.1	0.1	-0.1	-0.1	-0.9	-0.3	-0.6	-0.4	-0.2	0.9	0.4
Smoking status: Previous	0.2	0.4	1.7	-1.0	-0.6	-1.3	-0.3	-0.6	0.3	0.1	-0.1	-0.2	0.5	0.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.0	-0.6	0.4	0.0	-0.7	0.0	0.5	-1.0	-0.8	0.4	0.9	0.1
Myopia	0.2	0.4	1.1	0.7	0.2	-0.3	-0.2	-0.4	-1.1	-0.5	-0.9	-0.9	0.4	-0.3
Cholesterol lowering medication	0.2	0.3	0.7	-0.4	-0.3	-0.2	0.2	-0.7	-0.8	-0.7	0.7	0.8	0.2	0.6
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.7	-0.7	-0.7	-0.3	-0.1	-0.5	0.5	-0.1	-0.3	0.0	0.8	0.4
Crohns Disease (2017)	0.1	0.1	1.3	-0.0	-0.3	0.1	0.0	-0.2	0.3	0.0	1.1	0.1	-0.1	-0.3
Irritable Bowel Disease (IBD)	0.1	0.2	0.6	-0.5	-0.8	0.1	-0.4	-0.1	-0.5	-0.8	-0.2	-0.1	0.1	-0.5
Ulcerative Colitis (UC)	0.1	0.3	0.7	-0.5	-0.7	0.6	-0.3	0.5	-0.4	-0.6	-0.8	-0.1	0.4	0.0
Angina	0.1	0.2	0.8	0.3	0.2	0.2	0.2	-0.7	-0.4	-0.4	-0.2	-0.2	0.9	0.6
Heart attack	0.1	0.2	0.6	-0.5	-0.4	-0.1	0.1	-0.2	0.6	0.0	-0.2	0.2	0.8	0.5
Allergy	0.1	0.2	0.9	-0.1	-0.0	0.2	-0.2	-0.4	-0.1	0.4	0.1	-0.4	0.9	0.5
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.5	-0.2	0.4	-0.4	0.6	-0.3	-0.7	-0.4	-0.0	0.2	0.2	0.3
Medication: Omeprazole	0.1	0.1	0.3	0.3	-0.5	0.4	0.0	-0.0	-0.3	0.4	-0.4	-0.5	-0.3	-0.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.4	0.3	0.5	0.0	-0.1	0.6	0.0	-0.6	-0.6	-0.4	-0.2	0.1
Blood White Count	0.0	0.3	1.6	1.3	0.1	0.2	0.3	-0.1	-0.8	-0.1	-0.2	0.3	1.0	-0.0
Hair Pigment	0.0	0.8	2.0	1.2	1.4	-1.2	-0.3	0.0	-0.4	-0.5	-1.3	-1.0	0.2	0.4

Hub : Genes

CMTR2

Models

Trait associations