Hub : Genes

UTP15

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1100 0.0410 6.7e-04 0.047 NA 0.047 NA 0.048 9.5e-05 NA 9.1e-05 NA 8.8e-05
2 GTEx Adipose Visceral Omentum 0.1270 0.0530 3.9e-03 0.015 NA -0.004 NA 0.020 5.3e-02 NA 5.7e-01 NA 3.3e-02
3 GTEx Artery Tibial 0.1537 0.0447 9.3e-05 0.063 NA 0.035 NA 0.064 1.0e-05 NA 8.8e-04 NA 1.0e-05
4 GTEx Brain Cortex 0.1880 0.0760 4.6e-03 0.010 NA -0.011 NA 0.009 1.6e-01 NA 9.6e-01 NA 1.8e-01
5 GTEx Brain Hypothalamus 0.2940 0.1030 4.5e-03 0.126 NA 0.035 NA 0.045 7.4e-04 NA 5.2e-02 NA 3.3e-02
6 GTEx Breast Mammary Tissue 0.1260 0.0490 1.9e-03 0.082 NA 0.002 NA -0.001 5.2e-05 NA 2.4e-01 NA 3.6e-01
7 GTEx Cells Transformed fibroblasts 0.0730 0.0280 1.9e-03 0.089 NA 0.067 NA 0.073 3.2e-07 NA 9.4e-06 NA 3.8e-06
8 GTEx Colon Sigmoid 0.2230 0.0870 2.0e-03 0.022 NA 0.062 NA 0.025 5.5e-02 NA 3.1e-03 NA 4.5e-02
9 GTEx Colon Transverse 0.1010 0.0440 9.0e-03 0.059 NA 0.035 NA 0.074 8.5e-04 NA 8.7e-03 NA 2.0e-04
10 GTEx Esophagus Mucosa 0.1150 0.0390 3.1e-04 0.065 NA 0.040 NA 0.065 3.8e-05 NA 1.0e-03 NA 3.7e-05
11 GTEx Esophagus Muscularis 0.2170 0.0590 1.2e-06 0.158 NA 0.101 NA 0.143 7.9e-10 NA 9.9e-07 NA 5.2e-09
12 GTEx Testis 0.3460 0.0780 7.9e-10 0.299 NA 0.206 NA 0.288 9.6e-14 NA 1.7e-09 NA 3.2e-13
13 METSIM Adipose 0.0913 0.0234 9.5e-09 0.049 0.053 0.048 0.057 0.060 7.9e-08 1.9e-08 8.8e-08 5.6e-09 2.8e-09
14 ROSMAP Brain Pre-frontal Cortex 0.0612 0.0192 6.0e-05 0.023 0.029 0.029 0.030 0.032 5.5e-04 1.0e-04 1.0e-04 9.1e-05 4.9e-05
15 YFS Blood 0.0611 0.0146 1.7e-14 0.041 0.057 0.061 0.060 0.061 2.9e-13 5.7e-18 3.4e-19 6.6e-19 2.6e-19
16 TCGA Thyroid Carcinoma 0.0450 0.0250 7.6e-04 0.049 0.032 0.049 NA 0.047 1.4e-05 4.4e-04 1.4e-05 NA 2.1e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bipolar Disorder (2018) 0.3 0.5 2.4 0.3 0.5 0.3 -0.1 0.7 1.6 0.8 1.1 0.9 0.4 0.8 0.7 0.3 0.6 -0.5 0.2
Bipolar Disorder or Schizophrenia 0.1 0.3 1.7 -0.3 -0.2 -0.4 -1.3 -0.4 0.8 -0.1 0.3 0.1 -0.5 -0.4 -0.4 -0.5 -0.6 0.6 -0.3
Depressed Affect (Nagel 2018) 0.0 0.1 0.2 -0.0 -0.1 -0.0 -0.5 -0.3 0.4 0.2 0.4 0.3 0.1 -0.3 -0.0 -0.1 -0.1 0.2 -0.4
Depression (Nagel 2018) 0.3 0.4 2.0 0.8 -0.0 1.0 0.3 -0.2 1.4 -0.3 -0.4 -0.6 0.2 -0.4 -0.4 1.0 0.2 -0.2 1.1
Intelligence (Savage-Jansen 2018) 0.8 2.5 6.7 -1.3 -1.5 -0.8 -1.7 -2.0 -2.1 -1.6 -2.6 -1.5 -0.6 -1.3 -1.9 -1.2 -1.4 1.5 -0.9
Neuroticism (Nagel 2018) 0.8 1.9 3.5 -1.2 -1.8 -1.2 -1.9 -1.7 -0.4 -1.4 -1.1 -1.4 -1.1 -1.5 -1.4 -1.3 -1.6 1.5 -1.2
Schizophrenia (2018) 0.4 0.9 2.6 -0.7 -0.7 -0.8 -1.6 -1.1 -0.1 -0.8 -0.6 -0.6 -1.0 -1.2 -1.1 -0.7 -1.2 1.2 -0.6
Schizophrenia vs Biploar Disorder 1.8 2.4 6.6 -1.9 -1.3 -1.7 -1.6 -1.2 -2.6 -1.1 -2.2 -0.6 -1.3 -0.9 -0.9 -1.5 -1.4 1.4 -1.7
Worry (Nagel 2018) 1.1 2.3 3.7 -1.0 -1.9 -1.1 -1.5 -1.6 -0.3 -1.9 -1.9 -1.8 -1.4 -1.7 -1.9 -1.2 -1.6 1.4 -0.9
Alzheimer’s Disease (in mother) 0.9 1.1 3.3 1.5 1.0 1.8 1.1 0.3 0.0 0.4 0.6 0.2 0.2 0.9 0.4 1.3 1.0 -1.4 1.8
Alzheimer’s Disease (in father) 0.3 0.3 1.0 0.3 0.3 0.5 0.7 0.5 1.0 0.3 0.6 0.3 0.2 0.9 0.6 0.3 0.5 -0.7 0.2
Alzheimer’s Disease (including proxy) 0.6 0.8 2.2 1.1 0.8 1.5 1.2 0.6 0.1 0.4 0.4 0.3 0.1 1.2 0.5 1.0 0.8 -1.3 1.4
Crohns Disease (2017) 0.8 1.8 3.6 -0.7 -1.4 -0.9 -1.0 -1.3 -0.1 -1.8 -0.2 -1.9 -1.9 -1.7 -1.7 -1.8 -1.3 1.3 -0.4
Irritable Bowel Disease (IBD) 0.7 1.7 3.3 -1.1 -1.5 -1.0 -0.8 -1.1 -0.2 -1.7 0.2 -1.7 -1.6 -1.5 -1.4 -1.8 -1.4 1.4 -0.9
Ulcerative Colitis (UC) 0.1 0.2 0.5 -0.4 -0.6 -0.1 -0.2 -0.4 0.1 -0.6 0.7 -0.6 -0.7 -0.4 -0.4 -0.6 -0.5 0.4 -0.2
Major Depression (MDD) 0.3 0.4 4.0 0.1 0.0 0.0 0.4 0.6 2.0 -0.2 1.2 -0.3 -0.1 -0.2 0.2 -0.1 0.0 -0.0 0.2
Reaction Time 0.1 0.3 1.1 -0.6 -0.4 -0.4 -0.5 -0.6 -0.2 -0.5 -1.0 -0.4 -0.8 0.0 -0.4 -0.5 -0.3 0.2 -0.6
Verbal and Numeric Reasoning (VNR) 0.3 0.7 2.2 -0.4 -0.3 -0.2 -1.3 -1.1 -1.5 -0.7 -0.6 -0.8 -0.1 -1.2 -1.2 -0.4 -0.6 0.9 -0.0
Breast Cancer 1.2 2.9 4.3 1.8 2.0 2.0 1.9 1.2 0.6 1.6 0.4 1.6 1.8 1.9 1.8 2.0 1.9 -2.1 1.6
Ovarian Cancer 0.2 0.2 0.7 -0.6 -0.2 -0.4 -0.8 -0.6 -0.4 0.1 0.6 0.2 -0.4 -0.4 -0.2 -0.6 -0.3 0.6 -0.6
Prostate Cancer 0.2 0.3 1.5 -0.7 -0.4 -0.6 0.4 0.1 -0.6 -0.1 0.7 -0.2 -1.2 0.0 0.2 -0.0 -0.1 0.4 -0.6
Age at First Birth 0.4 0.5 1.1 -0.4 -0.6 -0.5 -0.8 -0.8 -0.5 -0.8 -0.8 -0.7 -1.0 -1.0 -0.9 -0.7 -0.6 0.8 -0.1
Bipolar Disorder (2011) 0.4 0.3 1.2 -0.7 -0.4 -0.9 -1.1 -0.3 0.3 0.0 -0.5 0.4 -0.5 -0.1 -0.1 -0.8 -0.6 0.5 -0.8
Body Mass Index (BMI) (2010) 2.4 3.3 5.3 -2.1 -2.0 -2.0 -1.6 -1.3 -0.6 -1.8 -1.0 -1.8 -1.9 -2.2 -1.9 -1.9 -1.9 2.3 -1.8
Coronary Artery Disease (CAD) 0.4 0.4 1.3 0.2 0.7 0.3 0.4 1.0 -0.9 0.8 0.4 1.1 0.8 0.4 1.0 0.1 0.3 -0.3 -0.0
Crohns Disease (2012) 0.9 1.4 3.3 -1.4 -1.2 -1.7 -0.8 -0.3 -0.8 -1.0 1.0 -1.0 -1.8 -1.0 -0.7 -1.5 -1.4 1.3 -1.4
Mean Putamen Volume 0.6 0.7 3.1 0.0 0.6 0.1 1.2 1.2 -0.4 1.1 1.8 0.9 0.8 0.4 1.0 0.7 0.6 -0.2 -0.2
Fasting Glucose 0.9 1.1 2.5 1.1 0.9 1.1 0.7 0.4 0.0 1.0 1.1 0.9 1.3 1.6 0.8 1.2 1.0 -1.5 0.9
HbA1C 0.4 0.5 2.8 -0.9 -0.5 -0.9 -0.3 0.9 -1.7 0.4 -0.1 0.3 0.2 0.3 0.2 -0.2 -0.3 0.5 -1.0
HDL Cholesterol 0.2 0.4 1.3 0.4 -0.2 0.0 -0.4 -1.1 -0.7 -0.9 0.3 -0.8 -1.0 -0.7 -1.0 -0.1 -0.2 0.2 0.6
LDL Cholesterol 0.1 0.1 0.4 -0.1 0.2 -0.1 -0.3 -0.4 -0.3 0.4 -0.6 0.5 0.1 0.4 0.1 -0.1 0.1 -0.2 -0.1
Lupus 0.2 0.2 0.8 0.9 0.4 0.7 0.4 -0.4 -0.6 -0.4 -0.2 -0.4 -0.2 -0.0 -0.5 -0.0 0.0 -0.4 0.8
Neuroticism (2016) 3.4 5.0 13.3 -3.4 -2.7 -3.6 -2.0 -0.8 -1.4 -1.3 0.9 -0.8 -1.5 -1.7 -1.1 -2.3 -2.2 2.8 -3.6
Primary Biliary Cirrhosis 1.1 1.6 5.5 -1.9 -0.8 -2.3 -1.3 0.4 -0.4 0.0 0.8 0.3 -0.9 -0.4 -0.1 -1.7 -1.4 1.3 -2.3
Rheumatoid Arthritis 0.9 1.2 2.7 -0.1 -0.8 -0.2 -1.3 -1.6 -0.3 -1.5 -0.4 -1.5 -0.7 -1.6 -1.6 -1.2 -1.1 0.9 0.2
Schizophrenia (2014) 0.3 0.6 3.2 -0.5 -0.7 -0.6 -1.8 -1.0 -0.7 -0.5 -0.2 -0.0 -0.5 -0.5 -0.7 -0.7 -1.0 0.7 -0.6
Triglycerides 0.6 0.9 1.6 0.8 1.1 0.8 0.8 1.1 -0.0 1.3 -0.4 1.2 1.1 0.9 1.2 0.9 1.1 -0.9 0.6
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.7 -0.9 -0.0 -0.8 0.2 1.3 0.3 0.9 0.2 1.3 0.7 0.2 0.9 0.3 0.1 0.4 -1.1
Ulcerative Colitis 1.5 2.2 6.1 -2.2 -1.6 -2.0 -1.5 -0.6 -2.1 -0.7 0.2 -0.2 -1.2 -0.3 -0.4 -1.8 -1.5 1.4 -2.5
Blood Eosinophil Count 0.6 4.7 7.7 1.4 2.0 1.8 2.1 2.6 2.1 2.5 2.2 2.5 2.8 2.7 2.7 1.1 2.0 -2.3 1.0
Blood Platelet Count 0.3 3.3 5.7 1.6 2.3 1.2 2.4 2.0 2.4 2.1 0.9 1.6 1.3 0.9 1.7 2.2 2.3 -1.5 1.6
Blood Red Count 0.0 0.4 1.6 -0.2 -0.6 0.2 0.7 0.6 1.0 -0.2 1.3 -0.6 0.5 -0.7 -0.2 0.3 0.1 0.6 -0.1
Blood White Count 1.1 8.5 16.3 1.5 3.1 1.6 3.5 3.5 2.9 4.0 1.3 3.6 2.4 2.9 3.7 3.2 3.6 -2.4 0.8
Heel T-Score 0.3 2.3 7.2 2.0 -0.3 2.0 1.7 0.0 1.0 -1.5 -1.7 -2.6 -1.2 -0.8 -1.0 1.5 0.2 -0.7 2.7
BMI 0.5 2.6 10.1 -2.7 -1.5 -2.8 -1.2 0.3 -1.5 -0.1 0.2 0.4 -0.6 -0.3 -0.2 -2.0 -1.6 1.7 -3.2
Height 0.1 1.9 6.3 -2.3 -1.3 -1.7 -0.3 0.6 -1.7 -0.5 -1.5 -0.2 -0.5 -0.1 -0.1 -1.9 -1.5 1.2 -2.5
Waist Hip Ratio (WHR) 0.1 0.3 2.1 0.3 0.2 -0.2 0.2 0.3 1.4 0.0 -0.3 -0.2 -0.4 -0.8 -0.3 0.3 0.1 0.3 0.5
Systolic Blood Pressure 0.0 0.2 0.5 -0.6 -0.7 -0.6 0.3 -0.2 0.3 -0.4 -0.5 -0.4 -0.4 -0.3 0.0 -0.1 -0.3 0.5 -0.6
Smoking Status 0.2 0.4 1.2 -0.9 -0.2 -0.9 -0.3 0.1 0.7 0.3 1.1 0.3 -0.5 -0.6 0.2 -0.4 0.0 0.9 -0.7
Allergy or Eczema 0.1 0.4 0.9 -0.8 -0.8 -0.7 -0.6 -0.3 -0.2 -0.6 0.7 -0.5 0.0 -0.4 -0.4 -0.8 -1.0 0.7 -0.8
Cardiovascular Disease 1.1 3.7 9.4 -0.1 1.4 0.2 2.1 2.9 1.9 2.9 1.1 2.7 1.9 1.9 3.1 1.3 1.9 -0.9 -0.6
Hypothyroidism (self reported) 0.2 0.5 1.8 -0.7 -0.2 -0.9 -0.5 -0.3 -0.6 -0.3 1.3 -0.2 -0.3 -0.8 -0.3 -1.0 -0.7 0.8 -0.7
Respiratory disease 1.1 2.4 5.3 1.5 1.4 2.0 2.1 1.9 1.3 1.1 1.5 0.7 2.3 1.0 1.6 1.3 1.4 -1.3 1.6
Type 2 Diabetes (T2D) (2018) 0.3 0.6 2.2 -1.3 -0.9 -1.2 -0.3 0.1 -0.3 -0.3 -0.3 -0.3 -0.4 -0.4 -0.1 -0.6 -0.8 1.0 -1.5
Lung FEV1/FVC ratio 1.0 5.0 9.1 -2.9 -2.4 -2.9 -3.0 -1.6 -1.2 -1.5 -0.2 -0.8 -2.0 -2.2 -1.8 -2.3 -2.6 2.9 -2.8
Lung FVC 0.3 1.6 4.9 0.6 0.4 1.0 2.0 2.2 1.6 0.7 1.8 0.3 1.6 1.2 1.2 0.9 0.9 -1.1 0.4
Neuroticism 0.4 1.0 2.9 -0.6 -1.3 -0.7 -1.5 -1.7 -0.4 -1.1 -0.5 -0.9 -0.4 -1.2 -1.1 -0.8 -1.1 1.0 -0.8
Chronotype (morning person) 0.8 1.9 3.7 -1.5 -1.4 -1.9 -0.7 -0.7 -1.5 -1.4 -0.2 -1.5 -1.5 -1.7 -1.3 -1.3 -1.3 1.7 -1.4
Hair Pigment 0.2 6.7 20.5 4.2 2.7 3.9 2.4 0.7 3.1 0.8 -0.2 -0.1 1.5 0.8 0.8 3.3 2.7 -2.8 4.5
Tanning 0.0 0.5 4.0 -0.6 -0.2 -0.5 0.4 1.2 0.4 0.5 2.0 0.6 0.5 0.5 0.6 -0.4 0.0 0.1 -0.7
Hand grip strength (left) 0.1 0.1 0.8 -0.1 -0.2 -0.1 -0.0 0.4 -0.8 -0.0 0.9 0.2 0.2 0.3 -0.1 -0.5 -0.3 -0.1 -0.0
Number of treatments/medications taken 1.9 3.5 7.7 0.8 2.0 0.9 2.7 2.8 1.7 2.4 1.6 1.9 2.2 1.4 2.6 1.6 1.8 -1.2 0.5
Average weekly spirits intake 1.9 2.3 3.7 1.9 1.5 1.9 1.3 0.7 1.9 1.0 1.7 0.6 0.9 1.4 1.0 1.9 1.6 -1.9 1.9
Sensitivity / hurt feelings 0.2 0.3 0.8 -0.5 -0.9 -0.2 -0.4 -0.8 0.5 -0.7 0.2 -0.6 -0.3 -0.7 -0.6 -0.3 -0.7 0.7 -0.2
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.7 -0.2 -0.6 0.0 -0.2 0.0 0.8 -0.3 0.2 -0.5 -0.6 -0.4 -0.4 -0.0 -0.3 0.4 0.0
Hearing difficulty/problems: Yes 12.8 19.6 41.9 -5.9 -4.2 -6.3 -5.3 -2.8 -5.3 -2.2 -2.8 -0.6 -3.6 -2.0 -2.6 -6.0 -4.9 4.4 -6.5
Relative age of first facial hair 0.6 1.1 6.6 -0.1 -0.7 -0.1 -1.7 -2.6 -1.1 -1.3 -1.0 -1.1 -0.6 -0.4 -1.3 -0.6 -0.8 0.2 -0.1
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.9 -0.2 0.3 0.0 0.4 0.5 0.1 0.2 -1.0 0.1 0.2 -0.2 -0.2 0.1 0.1 0.2 -0.1
Ever used hormone-replacement therapy (HRT) 0.5 0.6 2.3 1.0 0.8 1.4 0.4 -0.7 0.4 -0.1 -1.5 -0.3 0.0 0.1 -0.1 0.5 0.5 -0.7 1.5
Ever had hysterectomy (womb removed) 0.5 0.6 2.6 0.6 0.4 0.9 1.1 0.4 1.6 0.5 -0.5 0.2 0.9 0.3 0.3 0.8 0.8 -0.6 0.8
Systolic blood pressure, automated reading 0.4 1.2 3.3 -0.5 -1.2 -0.8 -0.6 -1.3 0.3 -1.5 -0.4 -1.8 -1.8 -1.4 -1.2 -0.5 -0.9 1.0 -0.2
Eye problems/disorders: Diabetes related eye disease 1.4 1.6 3.3 0.8 1.1 1.3 1.0 0.9 1.1 1.2 -1.8 1.1 1.8 1.5 1.2 1.6 1.3 -1.2 0.6
Angina 0.6 0.8 2.5 1.5 0.9 1.6 0.3 -0.2 1.3 0.3 -0.6 0.2 0.8 0.1 0.1 0.7 0.5 -0.8 1.5
Medication for hormone replacement therapy 0.2 0.3 0.9 0.6 0.2 0.8 0.2 -0.2 -0.2 0.2 -0.2 0.3 0.8 0.9 0.3 0.6 0.4 -0.8 0.5
Vitamin and mineral supplements 1.0 1.4 2.7 -1.2 -1.2 -1.2 -0.9 -1.3 -1.0 -1.0 -1.0 -1.3 -1.4 -1.6 -1.2 -0.6 -0.8 1.6 -0.8
Supplements: Zinc 0.2 0.2 1.5 0.2 0.2 0.2 -0.1 0.5 -0.0 0.3 -0.1 0.6 1.2 0.5 0.3 0.1 0.1 -0.4 0.2
Medication: Co-codamol 1.2 1.3 2.8 1.2 1.3 1.4 1.5 0.7 1.7 0.8 0.0 0.5 1.1 0.8 0.9 1.6 1.2 -1.2 1.3
Medication: Metformin 0.2 0.3 0.9 0.6 0.7 0.5 0.9 0.5 0.4 0.3 -0.9 0.1 0.0 -0.1 0.6 0.8 0.5 -0.3 0.6
Diabetes (father) 1.4 1.8 3.9 -2.0 -1.2 -1.9 -1.3 -0.6 -1.5 -0.5 0.1 -0.3 -1.3 -1.3 -0.4 -1.7 -1.4 1.8 -1.9
Diabetes (mother) 0.8 1.1 2.1 0.8 1.1 0.7 1.1 1.3 0.8 1.4 0.0 1.4 0.9 0.8 1.4 1.1 1.2 -0.8 0.7
Severe depression (siblings) 0.1 0.1 0.4 0.1 -0.2 -0.1 -0.4 -0.3 0.4 -0.4 -0.4 -0.3 -0.4 -0.6 -0.5 -0.1 -0.3 0.3 0.5
Pack years adult smoking proportion 1.3 2.0 5.6 0.2 1.1 0.3 1.1 1.6 1.0 1.9 1.8 2.1 1.2 2.4 1.7 0.7 1.1 -1.3 -0.6
Impedance of leg (right) 0.6 2.9 4.0 1.9 1.6 1.8 1.1 1.3 2.0 1.8 0.8 1.8 1.8 2.0 1.5 1.9 1.9 -2.0 1.6
Leg fat-free mass (left) 0.4 2.4 4.9 -2.1 -1.6 -2.0 -0.8 -0.4 -2.2 -1.1 -0.6 -0.9 -1.2 -1.1 -0.8 -2.1 -1.9 1.6 -2.2
Trunk fat percentage 0.2 0.7 3.4 -1.4 -0.3 -1.5 -0.4 0.8 0.0 0.7 0.2 1.0 0.3 0.3 0.6 -0.9 -0.6 0.5 -1.9
Hand grip strength (right) 0.0 0.1 0.4 -0.2 -0.2 -0.3 -0.3 0.1 -0.7 -0.4 0.7 -0.3 -0.3 -0.2 -0.4 -0.4 -0.5 0.2 -0.2
Townsend deprivation index at recruitment 0.2 0.3 1.0 -0.6 -0.4 -0.3 -0.5 -0.3 -0.8 0.0 -0.5 0.5 -0.0 0.9 -0.1 -0.8 -0.3 -0.0 -1.0
Current tobacco smoking 0.1 0.2 0.9 -0.5 -0.0 -0.3 -0.4 0.2 0.1 0.8 0.3 1.0 0.4 0.7 0.5 -0.2 0.3 0.0 -0.8
Average weekly fortified wine intake 0.1 0.1 0.3 0.1 0.6 0.1 -0.3 -0.2 -0.6 0.4 -0.5 0.6 -0.3 0.2 0.3 0.2 0.2 -0.3 0.1
Maternal smoking around birth 0.1 0.2 0.6 -0.5 -0.2 -0.3 0.6 0.6 -0.3 0.3 0.8 0.2 -0.4 0.1 0.3 0.1 0.1 0.2 -0.6
Fed-up feelings 0.3 0.5 1.7 -0.7 -0.6 -0.7 -1.3 -1.0 -0.7 0.1 -0.4 0.7 -0.5 0.0 -0.0 -0.8 -0.5 0.4 -1.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 1.2 0.3 -0.0 0.5 0.7 0.5 1.1 0.2 0.5 0.3 0.5 0.8 0.2 0.8 0.3 -0.5 0.2
Relative age voice broke 0.6 0.9 2.4 0.7 1.0 0.8 0.3 0.1 1.4 0.9 -1.2 1.1 1.6 1.2 0.9 0.7 0.9 -1.1 0.4
Taking other prescription medications 0.8 1.2 3.0 0.8 1.3 0.8 1.4 1.4 1.4 1.1 1.7 0.8 0.8 0.3 1.3 0.7 0.8 -0.7 0.9
Age when periods started (menarche) 0.1 0.2 0.6 -0.4 -0.5 -0.1 -0.5 -0.8 -0.1 -0.4 -0.7 -0.2 -0.3 0.7 -0.2 -0.2 -0.3 -0.2 -0.4
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 4.6 0.6 0.2 0.9 1.1 -0.1 2.2 -0.5 0.2 -1.1 -0.2 -0.8 -0.5 0.6 0.4 0.0 1.3
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 2.0 0.2 -0.4 0.2 0.9 0.5 1.0 -0.5 -1.4 -0.8 0.0 -0.5 -0.6 0.7 -0.0 0.1 0.6
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.3 -0.7 -0.8 -0.6 -0.5 -0.5 0.3 -0.6 -0.2 -0.8 -0.8 -1.2 -0.8 -0.3 -0.4 1.0 -0.4
Qualifications: CSEs or equivalent 1.5 2.0 5.5 -1.3 -1.7 -1.3 -1.2 -0.8 -2.4 -1.5 1.1 -1.2 -0.8 -1.0 -1.5 -1.8 -1.5 1.3 -1.3
Serious illness, injury or assault to yourself 1.2 1.5 6.5 -1.4 -1.1 -1.0 -0.7 -0.7 -0.3 -0.8 -2.5 -0.7 -0.7 -1.9 -1.1 -0.7 -0.9 1.8 -1.0
High blood pressure 0.5 1.4 4.5 0.2 0.8 0.4 2.1 2.0 2.1 1.3 0.6 0.9 0.5 0.4 1.6 1.0 1.2 -0.4 0.3
Hayfever, allergic rhinitis or eczema 0.2 0.5 1.4 -0.7 -0.8 -0.5 -0.7 -0.6 -1.2 -0.7 1.1 -0.5 -0.0 -0.3 -0.5 -0.8 -0.9 0.5 -0.5
Multivitamins +/- minerals 2.0 2.6 5.5 1.1 1.5 1.5 1.5 1.7 1.2 1.7 1.6 1.9 2.0 2.4 2.0 1.1 1.3 -1.9 0.6
Stomach or abdominal pain in last month 0.3 0.4 1.6 1.0 0.6 0.7 0.3 -0.4 -0.2 -0.0 -0.5 -0.3 -0.9 0.1 -0.2 0.7 0.5 -0.6 1.2
Supplements: Glucosamine 0.3 0.4 1.7 1.1 0.4 0.8 0.3 -0.2 0.9 -0.1 -1.3 -0.3 0.2 0.4 0.0 0.5 0.2 -0.8 1.1
Diverticular disease/diverticulitis (self-reported) 1.6 1.9 11.4 -0.2 0.9 -0.3 1.8 1.9 0.5 1.7 3.4 1.6 0.6 0.8 1.7 0.9 1.1 -0.2 -0.5
Medication: Atenolol 0.1 0.1 0.5 -0.1 -0.1 -0.0 -0.0 0.1 0.7 0.2 0.3 0.0 0.2 0.3 0.3 0.1 -0.0 -0.1 -0.3
Medication: Levothyroxine sodium 0.4 0.7 1.8 -0.3 -0.1 -0.7 -1.1 -1.0 -0.6 -0.6 -1.3 -0.4 -1.1 -1.3 -0.6 -1.2 -0.8 0.8 -0.0
Sitting height 0.1 1.0 3.7 -1.4 -0.3 -0.8 0.7 1.9 -1.2 0.7 0.4 0.8 0.9 0.6 1.2 -0.5 -0.3 0.3 -1.6
Chronic bronchitis/emphysema (father) 0.2 0.3 2.4 -0.2 -0.1 -0.3 -0.4 -0.4 0.5 -0.2 -1.5 -0.2 -0.1 -0.7 -0.6 -0.1 -0.1 0.4 -0.1
High blood pressure (mother) 0.2 0.2 0.7 -0.2 0.5 -0.2 0.5 0.3 0.0 0.7 -0.3 0.7 0.4 0.4 0.8 0.6 0.5 -0.1 -0.3
Body mass index (BMI) 0.4 1.7 4.1 -1.9 -1.3 -2.0 -0.8 -0.2 -0.7 -0.7 -0.8 -0.6 -1.3 -1.0 -0.6 -1.6 -1.4 1.5 -2.0
Impedance of leg (left) 0.9 4.2 7.7 1.9 1.9 1.8 1.5 2.0 2.8 2.2 1.2 2.3 2.2 2.2 2.0 2.2 2.3 -2.2 1.6
Leg predicted mass (left) 0.5 2.4 5.3 -2.1 -1.6 -2.0 -0.8 -0.4 -2.3 -1.1 -0.5 -0.9 -1.2 -1.0 -0.8 -2.1 -1.9 1.6 -2.2
Trunk fat mass 0.3 1.1 5.0 -1.8 -0.6 -1.8 -0.4 0.8 -0.3 0.4 -0.1 0.6 -0.0 -0.1 0.4 -1.4 -1.0 1.0 -2.2
Waist circumference 0.6 2.3 5.2 -2.0 -1.4 -2.3 -1.1 -0.5 -0.5 -1.0 -1.3 -0.9 -1.6 -1.8 -1.1 -1.8 -1.7 2.0 -2.0
Number of incorrect matches in round 0.3 0.5 2.3 1.0 0.2 0.7 1.0 0.2 1.5 -0.2 0.3 -0.6 0.3 -0.7 -0.0 1.0 0.4 -0.2 1.3
Past tobacco smoking 0.4 0.8 2.3 1.2 0.8 1.3 0.3 0.2 0.0 0.6 -0.8 0.8 0.9 1.5 0.4 0.8 0.8 -1.5 0.9
Alcohol usually taken with meals 2.0 3.3 5.5 -1.4 -1.7 -1.4 -2.3 -2.0 -1.9 -2.2 -0.9 -2.0 -1.7 -1.6 -2.3 -1.8 -2.1 1.7 -1.2
Nervous feelings 1.5 2.7 4.5 -1.3 -2.1 -1.5 -1.7 -1.7 -0.8 -2.0 -1.6 -1.9 -1.9 -1.6 -1.8 -1.4 -1.7 1.6 -1.3
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 3.1 0.5 0.6 0.7 0.8 0.6 1.8 1.0 0.2 0.7 0.2 0.5 1.1 1.0 1.0 -0.6 0.7
Hearing difficulty/problems with background noise 8.2 13.2 25.7 -4.6 -3.5 -4.8 -4.6 -2.7 -4.4 -2.2 -2.0 -1.0 -3.0 -1.9 -2.5 -5.1 -3.9 3.5 -5.0
Hair/balding pattern: Pattern 2 0.4 0.5 1.5 -0.3 0.4 0.0 0.6 1.0 -0.4 0.9 1.2 0.9 0.6 0.9 0.8 0.4 0.6 -0.2 -0.4
Had menopause 3.8 4.8 8.1 -2.9 -2.4 -2.8 -1.5 -1.0 -1.4 -1.9 -0.4 -1.9 -2.5 -2.4 -1.7 -2.6 -2.6 2.8 -2.6
Had other major operations 0.5 0.6 1.6 -1.1 -0.8 -0.9 -0.0 0.4 0.5 -0.5 -0.4 -0.8 0.0 -1.1 -0.4 -0.5 -0.8 1.2 -0.9
Forced vital capacity (FVC) 0.6 2.2 5.6 0.5 0.9 1.1 1.6 2.3 0.6 1.6 1.6 1.7 2.4 2.0 1.8 1.0 1.2 -1.4 0.0
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 3.0 0.4 -0.1 0.4 1.0 1.0 1.2 -0.0 -1.7 -0.4 0.1 -0.2 -0.1 0.9 0.3 -0.2 0.7
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 3.0 -0.9 -0.2 -1.0 0.8 1.6 1.7 0.5 1.6 0.4 -0.3 -0.2 0.5 0.2 0.2 0.6 -1.1
Qualifications: None of the above 0.2 0.4 2.4 -0.1 -0.5 -0.2 0.2 0.0 1.3 -0.6 -0.8 -0.8 -1.6 -0.3 -0.3 -0.4 -0.5 0.2 0.2
Financial difficulties in last 2 years 0.1 0.2 1.0 -0.5 -0.4 -0.2 0.6 1.0 0.5 0.0 0.5 -0.1 0.4 0.3 -0.2 -0.1 -0.2 0.2 -0.6
Mouth/teeth dental problems 0.3 0.5 1.5 0.4 0.6 0.7 1.1 1.2 0.1 0.6 -0.1 0.4 0.8 0.3 0.9 0.9 0.8 -0.4 0.5
Heart attack 1.6 2.0 2.9 1.1 1.6 1.3 1.5 1.5 1.2 1.7 1.4 1.5 1.4 1.5 1.6 1.7 1.5 -1.4 0.9
Allergy 0.3 0.6 1.5 -0.9 -0.7 -1.0 -0.9 -0.6 -0.3 -0.3 -1.2 -0.3 -1.1 -0.7 -0.6 -0.7 -0.6 0.9 -1.0
Pain all over the body in last month 3.1 3.4 5.0 2.1 1.9 2.2 1.9 1.3 1.2 1.7 0.9 1.5 1.7 1.9 1.9 2.0 2.1 -2.2 2.2
Diabetes (self-reported) 0.4 0.6 1.1 -0.9 -0.9 -0.8 -0.1 0.1 -0.0 -0.7 -0.1 -0.9 -1.0 -1.0 -0.5 -0.6 -0.9 1.1 -0.8
Hayfever/allergic rhinitis (self-reported) 0.1 0.2 0.6 -0.3 0.0 0.1 0.2 0.4 -0.2 0.6 0.1 0.8 0.6 0.5 0.6 0.2 0.3 -0.1 -0.3
Medication: Ramipril 1.6 2.1 4.0 1.1 1.4 1.2 2.0 1.6 1.8 1.4 1.3 1.0 1.6 1.1 1.8 1.6 1.5 -1.3 1.0
Medication: Simvastatin 0.4 0.6 1.6 -1.3 -0.1 -1.2 0.0 1.2 0.2 0.8 -1.0 0.8 -0.2 -0.1 1.0 -0.7 -0.3 0.7 -1.2
Fluid intelligence score 0.8 1.6 3.2 -1.0 -1.0 -0.9 -1.8 -1.6 -1.4 -1.3 -1.3 -1.4 -0.4 -1.4 -1.6 -1.1 -1.3 1.3 -0.6
Illnesses of siblings 0.6 0.9 2.3 1.5 0.7 1.5 0.3 -0.2 0.7 0.2 -0.1 0.3 1.1 1.0 0.2 1.0 1.0 -1.4 1.5
Neuroticism score 1.7 3.6 6.3 -1.9 -2.3 -1.9 -2.5 -2.2 -1.5 -1.7 -0.8 -1.4 -1.3 -2.0 -1.8 -2.0 -2.1 2.2 -2.0
Weight 0.6 2.9 7.0 -2.6 -1.8 -2.5 -1.1 -0.3 -1.3 -1.1 -0.9 -0.9 -1.4 -1.3 -0.9 -2.3 -2.1 2.0 -2.6
Impedance of arm (right) 0.2 1.0 2.6 0.9 0.9 0.9 0.1 0.6 -0.1 1.3 1.1 1.6 1.4 1.5 1.0 0.7 0.9 -1.1 0.6
Arm fat percentage (right) 0.2 1.0 4.3 -1.7 -0.7 -1.8 -0.5 0.5 -0.4 0.2 -0.4 0.4 -0.4 -0.3 0.2 -1.2 -0.9 1.1 -2.1
Trunk fat-free mass 0.4 2.4 4.7 -2.0 -1.7 -1.9 -0.7 -0.2 -1.5 -1.5 -1.0 -1.4 -1.6 -1.4 -1.0 -2.2 -2.0 1.7 -1.9
Hip circumference 0.5 2.0 4.0 -1.8 -1.4 -1.9 -1.3 -0.7 -1.4 -1.0 -1.0 -0.8 -1.2 -1.1 -0.9 -2.0 -1.8 1.4 -1.9
Time employed in main current job 0.5 0.6 1.1 0.9 1.0 0.9 1.0 0.7 0.7 0.6 -0.0 0.4 0.4 0.2 0.6 1.0 1.0 -0.7 1.0
Alcohol intake versus 10 years previously 0.2 0.3 0.7 0.3 0.5 0.5 0.3 0.3 0.8 0.6 -0.6 0.9 0.8 0.2 0.6 0.1 0.6 -0.3 0.2
Father’s age at death 0.3 0.4 1.1 -0.2 0.4 -0.1 0.8 1.0 0.5 0.8 0.4 0.7 1.0 1.0 0.9 0.7 0.4 -0.3 -0.5
Worrier / anxious feelings 1.5 2.8 5.2 -2.3 -2.2 -1.9 -1.5 -1.2 -1.4 -1.5 -1.3 -1.3 -1.2 -1.3 -1.4 -1.8 -1.9 2.0 -2.1
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 4.0 -0.4 0.4 0.0 1.2 1.6 2.0 1.2 -0.1 1.1 0.8 0.9 1.2 0.8 0.7 -0.2 -0.6
Falls in the last year 2.0 2.7 4.2 1.8 1.8 1.8 2.0 1.5 1.7 1.3 1.1 1.2 1.0 2.0 1.5 1.8 1.6 -2.0 1.6
Hair/balding pattern: Pattern 3 0.2 0.2 1.0 0.3 -0.1 -0.1 0.0 -0.2 0.8 -0.6 0.8 -0.5 -1.0 -0.4 -0.5 -0.1 -0.4 -0.0 0.4
Number of live births 0.1 0.2 0.7 -0.2 0.3 -0.2 0.3 0.5 -0.4 0.6 -0.4 0.9 0.1 0.6 0.6 0.1 0.2 -0.3 -0.4
Forced expiratory volume in 1-second (FEV1) 0.3 0.9 3.3 -0.2 0.2 0.2 0.8 1.8 0.2 1.1 1.2 1.2 1.6 1.0 1.2 0.3 0.3 -0.4 -0.6
Pulse rate 0.3 0.5 1.7 1.0 0.8 0.8 0.9 0.2 0.5 0.4 0.2 -0.0 -0.5 -0.3 0.1 1.2 1.0 -0.4 1.3
Happiness 0.3 0.4 2.4 -0.6 -0.4 -0.6 -0.2 0.6 1.5 0.2 0.2 0.1 -0.6 -0.8 0.1 -0.1 0.2 0.9 -0.5
Noisy workplace 0.4 0.5 1.6 0.7 0.6 0.8 1.3 1.1 1.2 0.6 0.2 0.3 0.2 0.2 0.6 0.7 0.7 -0.4 0.8
Qualifications: A levels/AS levels or equivalent 0.1 0.2 1.0 -0.3 -0.1 -0.2 -0.7 -0.7 -1.0 -0.3 -0.8 -0.3 0.3 -0.1 -0.4 -0.4 -0.3 0.2 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.8 -0.0 0.1 -0.0 0.3 0.2 -0.9 -0.1 -0.2 -0.1 -0.0 -0.1 -0.0 -0.1 -0.2 0.0 -0.1
Mouth/teeth dental problems: Dentures 1.2 2.1 5.2 -1.4 -1.6 -1.8 -1.8 -1.1 -1.8 -1.1 -0.2 -0.4 -1.5 -0.1 -0.9 -2.3 -1.9 1.0 -1.9
Asthma 1.3 2.5 6.2 0.9 1.2 1.4 2.5 2.4 1.4 1.3 1.7 0.8 2.4 1.2 1.6 1.4 1.5 -1.1 1.0
Medication: Ibuprofen (e.g. Nurofen) 3.5 4.4 8.4 1.5 2.1 1.9 2.9 2.0 1.3 2.1 2.7 1.6 2.8 1.5 2.0 2.7 2.4 -1.7 1.5
Medication: Cholesterol lowering 1.4 2.1 5.9 -0.7 1.1 -0.4 0.9 2.1 0.9 2.4 0.1 2.4 2.0 1.4 2.3 0.7 1.1 -0.4 -0.9
Depression (self-reported) 0.4 0.5 2.3 0.8 0.3 0.6 -0.0 -0.5 1.5 -0.3 0.4 -0.7 -0.5 -1.2 -0.3 0.6 0.2 0.3 1.2
Medication: Lansoprazole 0.4 0.5 1.6 0.8 0.1 0.6 -0.3 -1.2 0.0 -0.7 -1.0 -0.9 -0.6 -0.6 -0.6 0.1 -0.0 -0.2 1.2
Prospective memory result 0.3 0.4 1.4 1.0 0.4 0.9 0.3 -0.1 1.2 -0.0 -0.8 -0.2 0.5 -0.2 0.0 0.3 0.4 -0.5 1.2
Lung cancer (father) 0.8 1.0 1.7 -1.3 -1.0 -1.2 -0.6 -0.2 0.2 -0.8 -0.4 -0.7 -1.0 -1.3 -0.8 -1.3 -1.1 1.3 -1.1
Illnesses of mother 0.3 0.3 2.6 -0.1 -0.6 -0.1 -0.7 -0.6 -0.5 -0.5 1.6 -0.3 0.1 -0.3 -0.7 -0.4 -0.4 0.2 -0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 4.1 0.3 0.6 0.7 1.1 2.0 0.7 1.1 1.5 1.2 1.9 1.0 1.3 0.8 0.6 -0.8 -0.0
Pulse wave Arterial Stiffness index 1.7 2.0 4.9 0.4 1.7 0.5 1.3 1.8 1.3 2.0 1.0 2.0 1.5 1.2 2.2 1.1 1.5 -0.9 0.2
Impedance of arm (left) 0.3 1.5 3.8 1.0 1.1 1.1 0.2 0.6 0.3 1.5 1.1 1.9 2.0 1.8 1.2 1.1 1.1 -1.3 0.6
Arm fat mass (right) 0.5 1.9 5.9 -2.2 -1.3 -2.3 -1.0 0.0 -0.8 -0.5 -0.8 -0.3 -1.0 -1.0 -0.5 -1.8 -1.6 1.6 -2.4
Trunk predicted mass 0.4 2.4 4.5 -2.0 -1.7 -1.9 -0.7 -0.2 -1.5 -1.4 -1.0 -1.3 -1.6 -1.4 -1.0 -2.1 -2.0 1.7 -1.9
Standing height 0.1 1.3 3.2 -1.7 -1.3 -1.4 -0.8 -0.0 -1.4 -0.9 -0.2 -0.6 -0.3 -0.7 -0.6 -1.8 -1.6 1.2 -1.6
Length of working week for main job 0.7 0.7 3.3 -0.9 -1.1 -0.7 0.6 -0.3 -0.3 -0.9 1.8 -1.2 -0.7 -0.7 -0.7 -0.6 -0.5 0.9 -0.5
Exposure to tobacco smoke at home 2.1 2.3 12.3 -1.1 -1.1 -1.1 -1.7 -2.0 -0.4 -1.2 -3.5 -1.1 -1.3 -1.3 -1.5 -1.5 -1.3 1.2 -0.9
Breastfed as a baby 0.2 0.3 1.5 0.3 0.5 0.2 0.7 1.2 1.2 0.3 0.2 0.1 -0.2 -0.3 0.5 0.3 0.1 -0.0 0.4
Tense / ‘highly strung’ 0.7 1.2 2.4 -1.4 -1.6 -1.4 -1.0 -0.5 0.5 -0.9 -1.1 -0.9 -0.7 -1.4 -0.9 -0.8 -1.2 1.5 -1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.3 -0.9 -0.2 -0.8 0.1 1.1 -0.4 0.2 0.6 0.2 -0.6 -0.2 0.3 -0.4 -0.4 0.5 -0.9
Hair/balding pattern: Pattern 4 1.0 2.5 11.4 -1.2 -1.8 -1.0 -1.3 -1.0 -0.3 -1.8 -3.4 -1.8 -1.3 -1.4 -1.7 -1.3 -1.7 1.4 -1.0
Birth weight of first child 2.9 5.2 11.5 -3.2 -2.6 -3.4 -1.8 -1.0 -2.4 -1.6 -0.2 -1.4 -2.0 -1.7 -1.6 -2.7 -2.6 2.7 -3.2
Peak expiratory flow (PEF) 0.3 0.7 2.3 -0.9 -0.3 -0.5 0.5 1.5 0.3 0.7 1.1 0.7 1.2 0.7 0.8 -0.0 -0.2 0.2 -1.4
Pulse wave reflection index 6.8 8.4 14.9 1.6 3.0 1.7 2.5 3.6 2.5 3.6 1.3 3.7 3.9 3.8 3.8 2.2 2.8 -2.9 0.7
Ever highly irritable/argumentative for 2 days 0.1 0.1 0.5 0.2 0.0 0.2 0.3 0.4 0.6 0.0 0.7 -0.1 0.0 0.3 0.1 0.0 0.0 -0.2 0.2
Loud music exposure frequency 0.2 0.2 0.8 -0.4 -0.5 -0.4 -0.0 0.6 0.4 -0.1 0.9 -0.1 -0.2 0.0 0.1 -0.5 -0.4 0.3 -0.5
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 3.6 -0.9 -0.9 -0.4 -1.4 -1.4 -1.9 -0.8 -1.7 -0.3 0.3 -0.0 -1.0 -1.3 -0.7 0.6 -0.9
Mouth/teeth dental problems: Bleeding gums 0.6 0.7 2.1 -0.4 -0.9 -0.5 -0.7 -1.4 -0.1 -1.1 -0.8 -1.2 -0.7 -0.9 -1.4 -0.3 -0.6 0.7 -0.3
Blood clot in the leg (DVT) 2.2 2.8 6.1 2.2 1.9 1.9 1.7 1.2 2.5 1.2 1.0 0.9 1.0 1.0 1.4 2.0 1.8 -1.8 2.2
Medication: Paracetamol 0.4 0.6 1.1 1.1 1.1 1.0 0.6 0.4 1.0 0.7 -0.1 0.5 0.2 0.9 0.6 0.8 0.9 -1.0 1.0
Headache pain in last month 0.9 1.5 5.4 1.1 1.2 1.0 1.6 1.5 0.5 1.0 2.3 0.9 1.0 1.0 1.0 1.4 1.2 -1.1 0.8
Medication for cholesterol, blood pressure or diabetes 2.3 3.8 9.5 0.1 -1.7 -0.2 -2.0 -3.1 -1.7 -2.9 -1.0 -2.7 -2.6 -1.9 -3.1 -1.1 -1.6 1.0 0.7
Glaucoma (self-reported) 0.7 0.9 3.9 -0.3 0.6 -0.2 0.4 1.0 -1.0 1.5 0.3 2.0 1.2 1.0 1.2 0.4 0.7 -0.3 -0.7
Gout (self-reported) 1.8 2.5 5.5 -0.2 -1.3 -0.4 -1.6 -2.2 -1.1 -2.3 -1.2 -2.3 -1.3 -2.1 -2.3 -1.4 -1.5 1.1 0.4
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.9 -0.7 -0.2 -1.0 -0.8 -0.6 -0.5 -0.4 0.6 -0.3 -0.8 -1.4 -0.4 -1.2 -0.8 1.1 -0.4
Medication: Amlodipine 0.6 0.8 2.5 0.4 0.8 0.6 1.1 0.9 1.6 0.9 0.8 0.9 1.2 1.0 0.9 0.7 0.9 -0.8 0.2
Medication: Ventolin 100micrograms inhaler 4.1 5.3 11.9 1.3 1.7 1.4 2.9 3.5 1.4 2.6 2.7 2.3 2.8 2.6 3.0 1.9 2.3 -2.0 0.9
Birth weight 0.7 1.6 2.8 -0.8 -1.1 -0.8 -1.3 -1.2 -1.5 -1.5 0.2 -1.3 -1.0 -1.7 -1.6 -1.7 -1.5 1.3 -0.4
Chronic bronchitis/emphysema (mother) 0.2 0.2 0.6 0.5 0.0 0.5 0.2 -0.5 -0.4 -0.4 -0.7 -0.5 -0.7 0.4 -0.3 0.0 0.0 -0.4 0.4
High blood pressure (siblings) 0.1 0.1 0.5 -0.4 0.2 -0.4 0.4 0.7 -0.4 0.4 -0.4 0.3 -0.4 -0.1 0.5 -0.1 -0.2 0.3 -0.4
Forced vital capacity (FVC), Best measure 0.7 2.7 6.5 0.9 1.1 1.4 2.0 2.6 1.1 1.6 1.5 1.5 2.5 1.8 1.9 1.4 1.3 -1.5 0.6
Body fat percentage 0.2 0.7 3.1 -1.3 -0.2 -1.4 -0.2 0.9 0.3 0.8 0.0 1.0 0.2 0.2 0.6 -0.8 -0.5 0.5 -1.8
Leg fat percentage (right) 0.1 0.4 1.6 -0.9 -0.2 -1.0 0.1 1.0 0.6 0.7 -0.5 0.7 -0.0 0.2 0.6 -0.6 -0.3 0.4 -1.3
Arm fat-free mass (right) 0.3 1.5 3.2 -1.8 -1.3 -1.6 -0.4 -0.1 -0.9 -1.0 -0.7 -0.9 -1.1 -1.2 -0.7 -1.6 -1.5 1.5 -1.7
Exposure to tobacco smoke outside home 0.8 1.0 3.1 -1.4 -0.9 -1.1 -0.9 -0.9 -1.8 -0.3 -1.4 0.1 -0.9 -0.2 -0.4 -1.2 -0.9 0.8 -1.3
Comparative body size at age 10 0.4 1.0 3.4 -1.3 -0.3 -1.2 -0.4 0.9 -1.0 0.9 0.9 1.6 0.5 1.2 1.2 -0.9 -0.5 0.1 -1.8
Number of full brothers 0.6 0.7 3.2 -0.7 -0.8 -0.6 -1.1 -1.3 -1.0 -0.7 -0.1 -0.6 -1.8 -0.5 -0.7 -0.5 -0.5 0.8 -0.5
Worry too long after embarrassment 1.2 1.9 3.5 -1.2 -1.9 -0.9 -1.7 -1.6 -0.7 -1.6 -0.6 -1.7 -0.5 -1.5 -1.7 -1.3 -1.7 1.5 -1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.4 3.3 0.9 1.2 1.0 1.1 1.4 0.9 1.3 1.8 1.2 0.9 0.9 1.4 1.3 1.0 -1.0 0.7
Wheeze or whistling in the chest in last year 1.0 1.9 5.6 0.5 0.7 0.8 2.0 2.4 1.7 1.5 2.3 1.0 0.8 0.8 1.7 0.9 1.2 -0.7 0.6
Number of children fathered 0.2 0.2 1.0 -0.3 -0.2 -0.3 0.0 0.2 0.9 -0.1 -0.1 -0.3 0.1 -1.0 -0.2 0.4 0.1 0.7 0.1
Reason for reducing amount of alcohol drunk: Health precaution 3.1 3.6 8.5 -0.9 -1.8 -1.1 -1.3 -2.1 -1.0 -2.7 -1.4 -2.9 -1.8 -2.7 -2.5 -1.6 -2.0 1.9 -0.4
Age at first live birth 0.3 0.6 2.7 -1.2 -0.5 -1.1 -0.3 0.8 -1.6 0.2 0.2 0.4 0.1 0.4 0.3 -0.6 -0.6 0.5 -1.5
Pulse wave peak to peak time 1.8 2.1 4.9 -0.5 -1.8 -0.5 -1.4 -1.8 -1.4 -2.1 -1.0 -2.0 -1.5 -1.1 -2.2 -1.2 -1.6 0.9 -0.3
Health satisfaction 1.1 1.4 4.7 -0.1 0.8 -0.1 1.3 2.2 1.2 1.7 1.5 1.6 0.6 0.8 1.5 1.2 1.2 -0.3 -0.2
Shortness of breath walking on level ground 0.5 0.6 3.2 0.0 0.4 0.1 0.8 1.4 1.8 0.9 1.1 0.6 0.3 0.5 0.8 0.5 0.6 -0.3 0.1
Qualifications: College or University degree 0.2 0.7 2.3 0.1 0.8 0.2 -0.2 0.9 -0.1 1.3 -0.1 1.5 1.2 1.4 0.9 0.4 0.7 -0.7 -0.3
Eye problems/disorders: None of the above 1.0 1.2 2.2 -0.7 -1.0 -0.9 -1.2 -1.5 -0.2 -1.3 -0.1 -1.3 -1.4 -1.3 -1.2 -1.4 -1.0 1.0 -0.7
Mouth/teeth dental problems: Loose teeth 0.2 0.3 0.8 -0.7 -0.2 -0.9 -0.5 -0.2 -0.5 0.0 0.7 0.1 -0.6 -0.3 -0.1 -0.6 -0.4 0.6 -0.9
Emphysema/chronic bronchitis 4.1 4.6 7.1 2.0 2.2 2.0 2.5 1.9 1.6 2.0 2.3 1.8 2.7 2.3 2.2 2.1 2.3 -2.3 1.8
Medication for pain relief, constipation, heartburn 1.2 2.1 3.7 -1.3 -1.7 -1.5 -1.9 -1.5 -1.8 -1.4 -0.9 -0.8 -1.2 -0.9 -1.4 -1.9 -1.6 1.2 -1.4
Neck or shoulder pain in last month 0.3 0.5 0.9 -0.7 -0.5 -0.5 -0.2 -0.4 -0.9 -0.7 0.5 -0.9 -0.9 -0.9 -0.7 -0.7 -0.9 0.8 -0.5
Medication: Blood pressure 2.0 3.6 7.2 1.2 1.8 1.2 2.4 2.7 2.3 2.3 1.0 1.9 2.1 1.4 2.5 1.7 2.1 -1.5 0.9
Angina (self-reported) 0.4 0.5 1.6 1.2 0.7 1.3 0.3 -0.2 1.2 0.2 -0.6 0.0 0.7 -0.1 0.0 0.6 0.3 -0.6 1.2
Migraine (self-reported) 0.9 1.1 3.4 1.1 0.9 1.2 1.8 1.5 1.6 0.3 1.2 -0.1 0.4 0.0 0.4 1.1 0.9 -0.6 1.1
Medication: Ibuprofen 2.0 2.4 5.1 1.2 1.5 1.5 2.2 1.3 0.7 1.4 2.1 1.0 2.2 0.9 1.3 2.3 1.8 -1.1 1.2
Medication: Allopurinol 0.4 0.6 1.4 0.8 0.1 0.6 -0.8 -1.2 -0.0 -1.0 -0.5 -1.0 0.0 -1.0 -1.0 -0.3 -0.3 0.1 1.1
Medication: Omeprazole 0.1 0.2 0.7 0.0 -0.4 0.0 -0.0 -0.1 -0.3 -0.6 -0.2 -0.8 -0.9 -0.4 -0.4 -0.4 -0.4 0.2 0.3
Medication: Seretide 50 evohaler 4.9 5.6 12.3 1.9 2.1 2.2 3.5 3.1 1.4 2.2 2.8 1.7 2.5 2.6 2.5 2.1 2.3 -2.4 1.7
Mean time to correctly identify matches 0.8 1.5 2.7 -1.5 -1.2 -1.5 -1.2 -1.0 -0.2 -1.2 -1.4 -1.0 -1.4 -0.8 -0.9 -1.7 -1.2 1.2 -1.5
Heart disease (mother) 0.9 1.1 3.8 -1.5 -0.4 -1.4 -1.0 0.4 -0.2 0.8 -1.7 1.3 -0.1 0.7 0.9 -1.1 -0.6 0.5 -1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.5 -0.5 -0.2 -0.3 0.4 0.4 -0.1 -0.3 0.6 -0.3 0.0 -0.2 -0.1 -0.7 -0.3 0.3 -0.6
Whole body fat mass 0.3 1.1 4.9 -1.8 -0.8 -1.9 -0.4 0.7 -0.4 0.2 -0.4 0.4 -0.2 -0.3 0.2 -1.4 -1.1 1.1 -2.2
Leg fat mass (right) 0.3 1.0 4.4 -1.7 -0.9 -1.8 -0.2 0.8 -0.1 0.1 -0.5 0.1 -0.5 -0.3 0.1 -1.3 -1.1 1.0 -2.1
Arm predicted mass (right) 0.2 0.9 2.4 -1.6 -1.0 -1.4 0.0 0.4 -0.6 -0.6 -0.4 -0.6 -0.7 -0.8 -0.2 -1.2 -1.1 1.1 -1.5
Pulse rate, automated reading 2.4 7.6 12.4 2.7 2.7 2.7 3.5 3.2 3.0 2.6 2.4 2.0 2.3 2.7 2.7 3.2 3.0 -2.8 2.3
Alcohol intake frequency. 0.2 0.5 1.6 -0.6 -0.5 -0.7 -0.0 0.0 1.2 -0.4 -1.3 -0.6 -0.6 -1.1 -0.5 -0.1 -0.5 1.0 -0.6
Comparative height size at age 10 0.9 4.7 8.5 -2.4 -2.3 -2.4 -2.1 -1.4 -2.4 -2.1 -1.7 -1.6 -1.8 -1.8 -1.8 -2.9 -2.8 2.2 -2.3
Number of full sisters 1.3 1.6 3.6 -1.3 -1.3 -1.1 -1.3 -1.3 -1.9 -1.2 0.0 -1.0 -1.3 -1.0 -1.2 -1.4 -1.4 1.3 -1.2
Suffer from ‘nerves’ 2.0 3.1 5.3 -1.5 -2.3 -1.7 -2.0 -1.6 -1.5 -2.0 -1.4 -1.8 -1.5 -1.7 -1.8 -1.6 -2.2 1.8 -1.7
Overall health rating 1.2 2.6 5.9 0.9 1.5 1.0 2.4 2.4 2.4 1.9 0.9 1.5 0.7 1.3 1.8 1.8 1.7 -1.2 1.0
Chest pain or discomfort 0.4 0.6 1.5 -0.9 -0.5 -1.1 -0.9 -0.8 0.3 -0.4 -0.3 -0.6 -1.2 -1.1 -0.6 -0.4 -0.8 1.1 -0.6
Had major operations 0.7 0.8 3.4 0.1 0.7 0.0 0.9 1.8 1.0 1.5 -0.4 1.3 0.3 0.4 1.2 0.7 1.0 -0.2 0.2
Age at last live birth 0.9 1.3 3.6 -0.6 0.6 -0.4 0.6 1.9 -0.4 1.6 1.1 1.9 1.4 1.5 1.6 0.2 0.7 -0.5 -1.1
Family relationship satisfaction 0.4 0.5 1.3 -0.2 0.3 -0.1 0.8 1.1 0.9 1.0 1.1 0.8 0.6 0.4 0.9 0.5 0.7 -0.0 -0.1
Leg pain on walking 0.5 0.6 3.3 -0.8 -0.7 -0.7 0.3 -0.1 1.8 -0.6 -0.3 -0.8 -1.2 -0.9 -0.8 0.3 -0.3 0.8 -0.4
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.5 0.0 -0.1 -0.2 -0.5 -0.7 0.3 -0.2 -0.6 -0.1 -0.2 -0.2 -0.1 -0.4 -0.0 0.1 -0.1
Commuting to job workplace: Car/motor vehicle 0.3 0.3 1.3 0.6 0.2 0.6 0.6 0.0 0.8 -0.6 -0.1 -1.1 -0.3 -0.6 -0.4 0.0 -0.0 -0.1 0.9
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 2.5 -0.7 -0.9 -0.8 -1.4 -1.5 -1.6 -1.1 -0.2 -0.9 -1.4 -0.5 -1.0 -1.2 -0.9 0.6 -0.6
Medication: Aspirin 2.4 3.2 9.5 1.7 2.1 1.9 1.8 1.5 3.1 1.8 -0.1 1.3 1.9 1.1 1.5 2.2 1.8 -1.6 1.6
Supplements: Vitamin C 0.5 0.5 1.4 0.9 0.6 0.8 0.9 1.1 1.2 0.2 -0.3 0.3 0.2 0.7 0.2 0.6 0.6 -1.0 1.0
Knee pain experienced in last month 0.4 0.6 2.1 -0.4 -0.7 -0.4 0.4 -0.1 0.8 -1.1 0.8 -1.4 -1.1 -1.2 -0.9 -0.1 -0.7 0.8 -0.2
Hypertension (Self-reported) 0.7 2.1 5.6 0.5 1.1 0.8 2.2 2.3 2.4 1.7 0.8 1.3 1.0 0.7 1.9 1.3 1.5 -0.7 0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 1.3 -0.6 -0.7 -0.4 -0.2 -0.1 -0.4 -0.2 -1.2 -0.3 -0.4 -0.3 0.0 -0.3 -0.4 0.5 -0.3
Illnesses of father: Heart disease 0.6 0.9 2.3 -0.4 0.6 -0.1 0.7 1.5 -0.8 1.3 1.5 1.4 0.4 1.0 1.4 0.3 0.6 -0.3 -0.5
Illnesses of siblings: Diabetes 0.3 0.4 1.7 -0.5 -0.3 -0.6 0.0 0.2 0.1 -0.5 0.6 -0.8 -0.8 -1.3 -0.5 -0.3 -0.4 0.9 -0.3
Smoking status: Previous 0.6 0.9 2.3 -1.2 -0.9 -1.4 -0.2 -0.1 -0.0 -0.7 0.8 -0.9 -1.2 -1.5 -0.5 -0.9 -0.9 1.5 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 0.9 0.1 -0.2 -0.0 -0.2 -0.3 -1.0 -0.6 -0.6 -0.5 -0.8 0.0 -0.4 -0.3 -0.3 -0.1 0.3
Whole body fat-free mass 0.3 2.0 3.9 -1.9 -1.5 -1.8 -0.6 -0.2 -1.7 -1.2 -0.6 -1.1 -1.4 -1.2 -0.8 -2.0 -1.8 1.5 -1.8
Leg fat-free mass (right) 0.4 2.0 4.3 -2.0 -1.4 -2.0 -0.7 -0.2 -2.0 -0.9 -0.3 -0.7 -1.1 -1.0 -0.7 -2.0 -1.7 1.6 -2.1
Arm fat percentage (left) 0.2 0.9 4.3 -1.6 -0.6 -1.7 -0.5 0.6 -0.3 0.4 -0.3 0.6 -0.1 -0.1 0.3 -1.1 -0.8 1.0 -2.1
Average weekly red wine intake 0.2 0.3 1.2 -0.1 -0.4 0.2 -0.0 -0.6 0.8 -0.6 -0.5 -1.1 -0.0 -0.3 -0.9 0.2 -0.2 0.2 0.2
Handedness (chirality/laterality): Left-handed 0.2 0.2 2.4 0.4 0.1 0.2 -0.1 -0.1 -0.1 0.0 -1.5 0.2 0.5 0.2 0.1 -0.2 -0.1 -0.4 0.3
Mood swings 0.8 1.5 5.0 -1.8 -1.2 -1.9 -1.5 -0.6 -1.5 -0.1 -0.1 0.3 -0.4 -0.7 -0.4 -1.5 -1.0 1.4 -2.2
Loneliness, isolation 0.9 1.3 2.6 -1.5 -1.2 -1.3 -1.3 -0.7 -0.3 -0.7 0.4 -0.5 -1.6 -1.1 -0.7 -1.2 -1.2 1.5 -1.5
Long-standing illness, disability or infirmity 1.0 1.6 3.8 0.3 1.4 0.6 1.5 1.9 1.8 1.9 -0.8 1.6 1.2 0.3 1.4 1.1 1.3 -0.3 0.4
Ever had bowel cancer screening 0.3 0.3 1.0 0.0 -0.2 -0.2 -0.6 -0.9 -0.5 -0.7 -0.4 -0.9 -0.1 -1.0 -0.8 -0.4 -0.5 0.5 0.1
Diabetes diagnosed by doctor 0.3 0.4 1.1 -1.0 -0.7 -0.9 0.1 0.5 -0.5 -0.4 -0.1 -0.6 -0.6 -0.8 -0.2 -0.4 -0.7 1.0 -1.0
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 2.1 0.4 0.8 0.4 0.9 1.5 0.4 1.4 1.2 1.4 1.3 1.1 1.3 0.6 0.9 -0.8 0.1
Friendships satisfaction 0.2 0.3 0.7 -0.6 -0.1 -0.8 -0.4 0.5 0.0 0.6 -0.5 0.7 -0.5 -0.1 0.5 -0.3 -0.0 0.5 -0.8
Qualifications: nursing, teaching 0.7 1.1 3.2 1.0 -0.4 0.9 -0.9 -1.8 -0.5 -1.2 -1.7 -1.2 -0.4 -0.8 -1.6 -0.1 -0.4 -0.1 1.3
Commuting to job workplace: Walk 0.2 0.2 1.3 -0.2 -0.1 0.0 -0.3 -0.6 -1.1 -0.3 -0.6 -0.2 -0.5 -0.0 -0.3 -0.3 -0.3 0.2 -0.2
Eye problems/disorders: Cataract 2.1 2.4 5.4 1.0 1.5 1.2 1.9 2.3 1.6 1.8 0.7 1.5 2.0 1.3 1.9 1.5 1.4 -1.3 1.0
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 1.7 0.9 0.8 0.9 0.6 -0.3 0.7 0.2 0.7 -0.2 -0.1 -0.1 -0.2 1.1 0.7 -0.5 1.3
Medication for cholesterol 0.6 1.0 1.8 -0.9 -1.1 -1.1 -0.9 -0.6 -0.3 -1.2 -0.1 -1.0 -1.2 -1.1 -1.3 -1.1 -1.0 1.1 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.2 0.2 0.5 -0.1 0.1 0.4 -0.1 0.2 0.4 0.2 -0.3 -0.0 0.4 0.2 0.1 -0.1 0.3
Back pain experienced in last month 0.9 1.4 3.7 -0.9 -1.1 -1.2 -0.8 -0.9 0.2 -1.2 -0.6 -1.3 -1.9 -1.6 -1.2 -1.1 -1.3 1.3 -0.7
Mineral and other dietary supplements 0.4 0.5 2.4 -0.5 0.5 -0.3 -0.1 0.7 -0.4 1.2 0.2 1.6 0.7 0.6 0.9 0.2 0.8 -0.0 -0.7
Breast cancer (self-reported) 1.7 2.0 4.4 -0.7 -1.6 -0.6 -1.6 -2.0 -0.3 -1.9 -0.6 -2.1 -0.9 -1.5 -2.0 -1.2 -1.6 1.2 -0.3
Asthma (self-reported) 1.1 2.1 6.0 0.8 1.0 1.2 2.3 2.3 1.1 1.2 1.8 0.7 2.5 1.0 1.5 1.1 1.3 -1.0 0.9
Osteoporosis (self-reported) 0.2 0.2 0.7 0.1 0.9 0.1 -0.2 0.1 -0.3 0.6 0.6 0.7 0.5 0.5 0.4 0.1 0.4 -0.4 0.2
Osteoarthritis (self-reported) 0.6 0.8 2.6 -0.3 -0.6 -0.3 -0.6 -1.5 -0.2 -0.9 -0.8 -1.0 -1.6 -1.6 -1.0 -0.2 -0.5 1.0 0.1
Medication: Aspirin 1.6 2.1 5.8 1.1 1.8 1.4 1.2 1.3 2.4 1.7 -0.5 1.3 1.8 0.8 1.4 1.7 1.5 -1.1 1.0
Medication: Gliclazide 0.2 0.3 1.1 -0.1 0.2 0.1 0.0 1.1 0.0 0.5 0.8 0.5 0.8 0.8 0.6 0.0 0.0 -0.3 -0.3
Illnesses of father: None of the above (group 1) 0.2 0.2 0.6 -0.4 -0.3 -0.6 -0.7 -0.2 -0.7 -0.3 0.2 0.0 0.2 -0.1 -0.2 -0.8 -0.5 0.3 -0.7
Smoking status: Current 0.1 0.1 0.6 -0.5 -0.3 -0.4 -0.7 -0.3 0.2 0.3 -0.3 0.4 0.1 0.3 0.0 -0.4 -0.0 0.2 -0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.2 3.8 0.5 0.7 0.9 1.3 1.9 1.5 1.1 0.7 0.9 1.7 0.9 1.2 1.1 0.8 -0.8 0.4
Whole body water mass 0.4 2.3 4.2 -2.0 -1.6 -1.9 -0.7 -0.3 -1.8 -1.2 -0.7 -1.1 -1.4 -1.3 -0.9 -2.0 -1.9 1.7 -1.9
Leg predicted mass (right) 0.3 1.8 4.2 -2.0 -1.3 -1.9 -0.6 -0.1 -1.9 -0.8 -0.3 -0.6 -1.0 -0.9 -0.5 -1.9 -1.6 1.5 -2.0
Arm fat mass (left) 0.3 1.3 4.8 -1.9 -1.0 -2.0 -0.6 0.5 -0.6 -0.1 -0.3 0.0 -0.6 -0.7 -0.1 -1.5 -1.2 1.3 -2.2
Number of self-reported non-cancer illnesses 1.2 2.1 5.6 0.1 1.2 0.4 1.9 2.4 1.4 2.0 1.2 1.8 1.2 1.3 2.1 1.1 1.3 -0.8 -0.0
Average weekly champagne plus white wine intake 1.3 1.7 4.5 -1.7 -1.4 -1.7 -1.4 -0.8 -2.1 -1.1 -0.6 -1.0 -1.0 -1.0 -1.0 -1.3 -1.3 1.4 -1.5
Miserableness 0.7 1.2 4.5 -1.3 -1.1 -1.3 -1.4 -0.9 -2.1 -0.3 0.8 0.1 -0.9 -0.6 -0.6 -1.1 -1.0 1.1 -1.5
Guilty feelings 1.4 2.0 4.6 -1.0 -1.6 -1.2 -1.8 -2.1 -1.7 -1.6 -0.6 -1.4 -1.4 -1.2 -1.5 -1.4 -1.6 1.2 -0.9
Wears glasses or contact lenses 2.0 2.4 3.7 -1.5 -1.7 -1.5 -1.3 -1.5 -0.6 -1.6 -0.8 -1.8 -1.6 -1.9 -1.8 -1.6 -1.7 1.8 -1.2
Ever taken oral contraceptive pill 1.5 1.7 5.1 -0.0 1.1 0.1 2.0 2.3 -0.3 1.6 2.1 1.4 1.0 0.8 1.7 1.2 1.2 -0.4 -0.3
Hearing aid user 19.2 21.7 33.4 -5.3 -4.9 -5.8 -4.9 -4.0 -3.8 -4.3 -2.6 -3.6 -4.7 -4.4 -4.3 -5.2 -5.3 5.2 -5.1
Mother’s age at death 1.5 1.9 4.6 -0.7 -1.2 -0.6 -1.2 -1.5 1.1 -1.8 -0.7 -2.1 -0.8 -2.1 -2.0 -1.3 -1.6 1.4 -0.2
Financial situation satisfaction 0.5 0.6 2.9 0.6 0.1 0.8 1.1 1.2 1.1 0.3 1.7 -0.1 0.3 0.1 0.1 0.8 0.7 -0.4 0.8
Tinnitus: Yes, now most or all of the time 0.2 0.2 0.9 -0.3 0.1 -0.4 -0.2 0.1 0.1 0.6 0.4 0.9 -0.5 0.6 0.4 -0.5 -0.1 -0.2 -0.3
Commuting to job workplace: Public transport 1.0 1.2 4.0 -0.9 0.4 -0.4 0.4 1.1 0.3 1.7 0.8 1.9 2.0 1.3 1.5 0.4 0.7 -0.2 -1.2
Eye problems/disorders: Glaucoma 0.3 0.4 1.8 -0.3 0.0 -0.3 -0.1 0.3 -1.1 0.8 -0.6 1.4 0.6 0.9 0.7 -0.0 0.3 -0.3 -0.5
Medication: Blood pressure 0.1 0.1 0.6 -0.1 0.2 0.1 0.5 0.4 0.8 0.3 -0.2 0.1 0.2 -0.3 0.5 0.4 0.2 0.2 -0.0
Pain type(s) experienced in last month: Hip pain 1.2 1.5 3.8 1.7 1.7 1.5 1.0 0.7 1.9 0.9 0.4 0.4 0.2 0.6 0.9 1.5 1.0 -1.3 1.6
Supplements: Fish oil (including cod liver oil) 0.6 0.8 3.9 0.9 -0.5 0.6 0.6 -0.4 1.0 -1.4 0.1 -2.0 -1.2 -0.7 -0.8 0.3 -0.4 -0.2 1.2
High cholesterol (Self-reported) 0.5 0.9 2.5 -1.4 0.2 -1.3 -0.5 0.7 -0.3 1.3 -0.5 1.5 0.6 0.5 1.3 -0.7 -0.1 0.5 -1.6
Medication: Bendroflumethiazide 0.1 0.2 0.5 0.3 0.4 0.2 0.1 0.2 0.7 0.7 -0.4 0.6 0.1 0.4 0.7 0.3 0.5 -0.4 0.3
Medication: Paracetamol 0.1 0.1 0.5 0.2 0.2 0.1 -0.5 -0.7 -0.1 -0.1 -0.6 -0.2 -0.7 -0.1 -0.3 0.1 -0.0 -0.0 0.2
Medication: Lisinopril 0.7 0.9 1.6 0.7 1.2 0.8 1.0 0.4 1.3 1.1 0.4 0.9 1.1 0.6 1.2 1.1 1.1 -0.9 0.5
Medication: Atorvastatin 4.5 5.6 11.7 1.9 2.8 2.3 2.2 1.8 1.7 2.6 2.1 2.3 3.4 2.7 2.6 2.5 2.3 -2.5 1.5
Illnesses of father: High blood pressure 0.2 0.3 1.1 0.6 0.2 0.8 -0.1 -0.8 -0.2 -0.3 0.2 -0.6 -0.7 -0.1 -0.4 0.4 0.1 -0.3 1.0
Alcohol drinker status: Never 0.2 0.2 1.2 -0.0 -0.2 -0.3 0.1 -0.1 0.0 -0.5 -1.1 -0.8 -0.8 -0.5 -0.5 -0.1 -0.7 0.3 0.1
Ever smoked 0.2 0.4 1.2 -0.9 -0.5 -1.0 -0.6 -0.4 -0.3 -0.2 0.4 -0.2 -0.1 -1.0 -0.4 -0.7 -0.5 1.1 -0.8
Basal metabolic rate 0.4 2.2 4.5 -2.1 -1.6 -2.0 -0.6 -0.1 -1.7 -1.1 -0.7 -0.9 -1.3 -1.1 -0.8 -2.0 -1.9 1.6 -2.1
Leg fat percentage (left) 0.2 0.7 2.2 -0.9 0.0 -1.1 0.4 1.5 1.1 1.0 -0.2 0.9 0.1 0.3 0.9 -0.5 -0.1 0.3 -1.4
Arm fat-free mass (left) 0.5 2.4 4.6 -2.1 -1.7 -2.1 -0.7 -0.1 -1.3 -1.2 -0.9 -1.2 -1.6 -1.5 -1.0 -2.0 -1.9 1.9 -2.0
Number of operations (self-reported) 0.4 0.7 2.0 0.1 0.4 0.2 1.2 1.4 1.4 0.8 -0.7 0.6 1.3 -0.5 0.6 0.9 0.7 0.2 0.3
Average weekly beer plus cider intake 2.1 3.1 5.7 2.2 1.7 2.1 1.6 1.4 1.4 1.4 1.2 1.3 1.9 2.2 1.5 1.4 1.8 -2.4 1.9
Irritability 0.9 1.5 2.8 -1.5 -1.3 -1.4 -1.7 -1.0 -0.7 -0.8 -0.8 -0.6 -0.8 -1.2 -0.9 -1.6 -1.4 1.5 -1.5
Risk taking 2.9 4.3 7.7 1.5 2.1 1.6 2.6 2.8 2.4 2.3 1.5 1.9 1.8 2.3 2.3 2.1 2.1 -2.0 1.3
Ever had prostate specific antigen (PSA) test 0.2 0.3 1.0 0.7 0.1 0.8 0.2 -0.3 0.6 -0.5 -0.0 -0.6 -0.3 -0.4 -0.6 0.3 0.2 -0.2 1.0
Fractured/broken bones in last 5 years 0.2 0.2 1.8 -0.3 -0.4 -0.4 -0.3 0.0 -0.4 -0.3 1.3 -0.2 -0.5 -0.4 -0.4 -0.7 -0.3 0.4 -0.1
Age started oral contraceptive pill 3.7 4.7 6.4 -2.1 -2.3 -2.3 -2.5 -2.3 -1.4 -2.0 -2.2 -1.9 -2.1 -2.2 -2.3 -2.1 -2.2 2.4 -2.0
Diastolic blood pressure, automated reading 0.9 2.6 6.1 1.5 1.6 1.4 2.5 1.7 2.0 1.4 1.4 0.8 0.7 1.2 1.7 2.2 1.9 -1.5 1.6
Ever depressed for a whole week 0.4 0.4 1.0 -0.9 -0.5 -0.9 0.6 0.8 1.0 -0.2 0.7 -0.6 -0.4 -0.6 -0.1 0.2 -0.2 0.8 -1.0
Unable to work because of sickness or disability 0.3 0.4 2.0 0.3 0.5 0.7 0.7 0.4 1.4 0.5 -0.0 0.4 -0.1 0.6 0.6 0.7 0.7 -0.5 0.4
Commuting to job workplace: Cycle 5.9 7.1 10.8 -2.0 -3.0 -1.9 -2.6 -3.1 -3.3 -3.2 -2.7 -2.8 -2.7 -2.1 -3.2 -2.7 -2.8 2.2 -1.6
Myopia 0.4 0.6 2.2 0.2 0.8 0.8 0.9 1.0 0.1 1.1 0.2 0.9 1.5 0.8 1.0 0.6 0.7 -0.6 -0.0
Vascular/heart problems diagnosed by doctor 0.9 2.6 7.1 -0.6 -1.4 -0.8 -2.4 -2.7 -2.5 -1.9 -1.0 -1.5 -1.0 -0.8 -2.2 -1.4 -1.6 0.8 -0.5
Cholesterol lowering medication 0.3 0.4 1.0 -0.7 0.2 -0.5 -0.1 0.6 -0.0 0.9 -1.0 0.9 0.7 0.5 0.8 -0.3 -0.0 0.1 -1.0
Medication: Omeprazole (e.g. Zanprol) 0.0 0.0 0.3 0.1 -0.1 0.1 0.3 0.3 -0.1 -0.0 0.1 -0.1 -0.5 0.1 0.1 -0.1 0.1 -0.1 0.3
Pain experienced in last month 0.4 0.6 1.7 -0.8 -0.3 -0.5 -1.2 -0.1 -1.3 0.5 -0.8 1.1 0.9 0.9 0.5 -0.8 -0.1 0.0 -1.1
Supplements: Calcium 1.9 2.1 3.8 1.8 1.8 1.8 1.4 1.3 1.2 1.2 0.2 1.3 1.2 1.7 1.4 1.2 1.4 -1.9 1.7
Basal cell carcinoma (self-reported) 0.1 0.1 0.3 -0.4 -0.0 -0.5 -0.2 0.3 -0.5 0.3 0.4 0.3 0.3 -0.2 0.2 0.2 0.0 0.3 -0.5
Heart attack/myocardial infarction (self-reported) 1.6 2.0 3.0 1.0 1.6 1.3 1.4 1.4 1.1 1.7 1.3 1.5 1.4 1.5 1.6 1.6 1.5 -1.4 0.8
Deep venous thrombosis (DVT) (self-reported) 1.8 2.3 5.7 2.1 1.8 1.8 1.5 0.9 2.4 1.0 0.6 0.7 0.8 0.8 1.1 1.8 1.6 -1.6 2.1
Heart disease (siblings) 0.4 0.5 1.9 -0.6 0.2 -0.3 0.7 1.4 0.3 0.8 1.2 0.8 0.5 0.5 1.0 -0.3 0.2 0.1 -0.7
Alcohol drinker status: Previous 1.1 1.2 4.9 0.9 1.3 0.8 0.9 1.4 2.2 1.1 0.6 1.1 0.6 0.9 1.2 1.1 1.1 -0.9 0.7
Pack years of smoking 0.7 1.1 3.3 0.1 0.7 0.1 0.7 1.2 0.9 1.4 1.5 1.5 0.6 1.8 1.2 0.5 0.7 -0.9 -0.6
Impedance of whole body 0.6 2.9 5.3 1.6 1.6 1.6 0.8 1.3 1.5 2.0 1.4 2.2 2.3 2.2 1.7 1.7 1.8 -1.9 1.2
Leg fat mass (left) 0.2 1.0 4.1 -1.6 -0.7 -1.7 -0.1 1.0 0.3 0.2 -0.4 0.2 -0.4 -0.4 0.2 -1.2 -0.9 1.0 -2.0
Arm predicted mass (left) 0.3 1.7 3.4 -1.8 -1.5 -1.8 -0.3 0.1 -1.1 -1.1 -0.6 -1.1 -1.4 -1.2 -0.8 -1.7 -1.6 1.5 -1.8