Hub : Genes

UTP15

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1100	0.0410	6.7e-04	0.047	NA	0.047	NA	0.048	9.5e-05	NA	9.1e-05	NA	8.8e-05
2	GTEx	Adipose Visceral Omentum	0.1270	0.0530	3.9e-03	0.015	NA	-0.004	NA	0.020	5.3e-02	NA	5.7e-01	NA	3.3e-02
3	GTEx	Artery Tibial	0.1537	0.0447	9.3e-05	0.063	NA	0.035	NA	0.064	1.0e-05	NA	8.8e-04	NA	1.0e-05
4	GTEx	Brain Cortex	0.1880	0.0760	4.6e-03	0.010	NA	-0.011	NA	0.009	1.6e-01	NA	9.6e-01	NA	1.8e-01
5	GTEx	Brain Hypothalamus	0.2940	0.1030	4.5e-03	0.126	NA	0.035	NA	0.045	7.4e-04	NA	5.2e-02	NA	3.3e-02
6	GTEx	Breast Mammary Tissue	0.1260	0.0490	1.9e-03	0.082	NA	0.002	NA	-0.001	5.2e-05	NA	2.4e-01	NA	3.6e-01
7	GTEx	Cells Transformed fibroblasts	0.0730	0.0280	1.9e-03	0.089	NA	0.067	NA	0.073	3.2e-07	NA	9.4e-06	NA	3.8e-06
8	GTEx	Colon Sigmoid	0.2230	0.0870	2.0e-03	0.022	NA	0.062	NA	0.025	5.5e-02	NA	3.1e-03	NA	4.5e-02
9	GTEx	Colon Transverse	0.1010	0.0440	9.0e-03	0.059	NA	0.035	NA	0.074	8.5e-04	NA	8.7e-03	NA	2.0e-04
10	GTEx	Esophagus Mucosa	0.1150	0.0390	3.1e-04	0.065	NA	0.040	NA	0.065	3.8e-05	NA	1.0e-03	NA	3.7e-05
11	GTEx	Esophagus Muscularis	0.2170	0.0590	1.2e-06	0.158	NA	0.101	NA	0.143	7.9e-10	NA	9.9e-07	NA	5.2e-09
12	GTEx	Testis	0.3460	0.0780	7.9e-10	0.299	NA	0.206	NA	0.288	9.6e-14	NA	1.7e-09	NA	3.2e-13
13	METSIM	Adipose	0.0913	0.0234	9.5e-09	0.049	0.053	0.048	0.057	0.060	7.9e-08	1.9e-08	8.8e-08	5.6e-09	2.8e-09
14	ROSMAP	Brain Pre-frontal Cortex	0.0612	0.0192	6.0e-05	0.023	0.029	0.029	0.030	0.032	5.5e-04	1.0e-04	1.0e-04	9.1e-05	4.9e-05
15	YFS	Blood	0.0611	0.0146	1.7e-14	0.041	0.057	0.061	0.060	0.061	2.9e-13	5.7e-18	3.4e-19	6.6e-19	2.6e-19
16	TCGA	Thyroid Carcinoma	0.0450	0.0250	7.6e-04	0.049	0.032	0.049	NA	0.047	1.4e-05	4.4e-04	1.4e-05	NA	2.1e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	0.3	0.5	2.4	0.3	0.5	0.3	-0.1	0.7	1.6	0.8	1.1	0.9	0.4	0.8	0.7	0.3	0.6	-0.5	0.2
Bipolar Disorder or Schizophrenia	0.1	0.3	1.7	-0.3	-0.2	-0.4	-1.3	-0.4	0.8	-0.1	0.3	0.1	-0.5	-0.4	-0.4	-0.5	-0.6	0.6	-0.3
Depressed Affect (Nagel 2018)	0.0	0.1	0.2	-0.0	-0.1	-0.0	-0.5	-0.3	0.4	0.2	0.4	0.3	0.1	-0.3	-0.0	-0.1	-0.1	0.2	-0.4
Depression (Nagel 2018)	0.3	0.4	2.0	0.8	-0.0	1.0	0.3	-0.2	1.4	-0.3	-0.4	-0.6	0.2	-0.4	-0.4	1.0	0.2	-0.2	1.1
Intelligence (Savage-Jansen 2018)	0.8	2.5	6.7	-1.3	-1.5	-0.8	-1.7	-2.0	-2.1	-1.6	-2.6	-1.5	-0.6	-1.3	-1.9	-1.2	-1.4	1.5	-0.9
Neuroticism (Nagel 2018)	0.8	1.9	3.5	-1.2	-1.8	-1.2	-1.9	-1.7	-0.4	-1.4	-1.1	-1.4	-1.1	-1.5	-1.4	-1.3	-1.6	1.5	-1.2
Schizophrenia (2018)	0.4	0.9	2.6	-0.7	-0.7	-0.8	-1.6	-1.1	-0.1	-0.8	-0.6	-0.6	-1.0	-1.2	-1.1	-0.7	-1.2	1.2	-0.6
Schizophrenia vs Biploar Disorder	1.8	2.4	6.6	-1.9	-1.3	-1.7	-1.6	-1.2	-2.6	-1.1	-2.2	-0.6	-1.3	-0.9	-0.9	-1.5	-1.4	1.4	-1.7
Worry (Nagel 2018)	1.1	2.3	3.7	-1.0	-1.9	-1.1	-1.5	-1.6	-0.3	-1.9	-1.9	-1.8	-1.4	-1.7	-1.9	-1.2	-1.6	1.4	-0.9
Alzheimer’s Disease (in mother)	0.9	1.1	3.3	1.5	1.0	1.8	1.1	0.3	0.0	0.4	0.6	0.2	0.2	0.9	0.4	1.3	1.0	-1.4	1.8
Alzheimer’s Disease (in father)	0.3	0.3	1.0	0.3	0.3	0.5	0.7	0.5	1.0	0.3	0.6	0.3	0.2	0.9	0.6	0.3	0.5	-0.7	0.2
Alzheimer’s Disease (including proxy)	0.6	0.8	2.2	1.1	0.8	1.5	1.2	0.6	0.1	0.4	0.4	0.3	0.1	1.2	0.5	1.0	0.8	-1.3	1.4
Crohns Disease (2017)	0.8	1.8	3.6	-0.7	-1.4	-0.9	-1.0	-1.3	-0.1	-1.8	-0.2	-1.9	-1.9	-1.7	-1.7	-1.8	-1.3	1.3	-0.4
Irritable Bowel Disease (IBD)	0.7	1.7	3.3	-1.1	-1.5	-1.0	-0.8	-1.1	-0.2	-1.7	0.2	-1.7	-1.6	-1.5	-1.4	-1.8	-1.4	1.4	-0.9
Ulcerative Colitis (UC)	0.1	0.2	0.5	-0.4	-0.6	-0.1	-0.2	-0.4	0.1	-0.6	0.7	-0.6	-0.7	-0.4	-0.4	-0.6	-0.5	0.4	-0.2
Major Depression (MDD)	0.3	0.4	4.0	0.1	0.0	0.0	0.4	0.6	2.0	-0.2	1.2	-0.3	-0.1	-0.2	0.2	-0.1	0.0	-0.0	0.2
Reaction Time	0.1	0.3	1.1	-0.6	-0.4	-0.4	-0.5	-0.6	-0.2	-0.5	-1.0	-0.4	-0.8	0.0	-0.4	-0.5	-0.3	0.2	-0.6
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.2	-0.4	-0.3	-0.2	-1.3	-1.1	-1.5	-0.7	-0.6	-0.8	-0.1	-1.2	-1.2	-0.4	-0.6	0.9	-0.0
Breast Cancer	1.2	2.9	4.3	1.8	2.0	2.0	1.9	1.2	0.6	1.6	0.4	1.6	1.8	1.9	1.8	2.0	1.9	-2.1	1.6
Ovarian Cancer	0.2	0.2	0.7	-0.6	-0.2	-0.4	-0.8	-0.6	-0.4	0.1	0.6	0.2	-0.4	-0.4	-0.2	-0.6	-0.3	0.6	-0.6
Prostate Cancer	0.2	0.3	1.5	-0.7	-0.4	-0.6	0.4	0.1	-0.6	-0.1	0.7	-0.2	-1.2	0.0	0.2	-0.0	-0.1	0.4	-0.6
Age at First Birth	0.4	0.5	1.1	-0.4	-0.6	-0.5	-0.8	-0.8	-0.5	-0.8	-0.8	-0.7	-1.0	-1.0	-0.9	-0.7	-0.6	0.8	-0.1
Bipolar Disorder (2011)	0.4	0.3	1.2	-0.7	-0.4	-0.9	-1.1	-0.3	0.3	0.0	-0.5	0.4	-0.5	-0.1	-0.1	-0.8	-0.6	0.5	-0.8
Body Mass Index (BMI) (2010)	2.4	3.3	5.3	-2.1	-2.0	-2.0	-1.6	-1.3	-0.6	-1.8	-1.0	-1.8	-1.9	-2.2	-1.9	-1.9	-1.9	2.3	-1.8
Coronary Artery Disease (CAD)	0.4	0.4	1.3	0.2	0.7	0.3	0.4	1.0	-0.9	0.8	0.4	1.1	0.8	0.4	1.0	0.1	0.3	-0.3	-0.0
Crohns Disease (2012)	0.9	1.4	3.3	-1.4	-1.2	-1.7	-0.8	-0.3	-0.8	-1.0	1.0	-1.0	-1.8	-1.0	-0.7	-1.5	-1.4	1.3	-1.4
Mean Putamen Volume	0.6	0.7	3.1	0.0	0.6	0.1	1.2	1.2	-0.4	1.1	1.8	0.9	0.8	0.4	1.0	0.7	0.6	-0.2	-0.2
Fasting Glucose	0.9	1.1	2.5	1.1	0.9	1.1	0.7	0.4	0.0	1.0	1.1	0.9	1.3	1.6	0.8	1.2	1.0	-1.5	0.9
HbA1C	0.4	0.5	2.8	-0.9	-0.5	-0.9	-0.3	0.9	-1.7	0.4	-0.1	0.3	0.2	0.3	0.2	-0.2	-0.3	0.5	-1.0
HDL Cholesterol	0.2	0.4	1.3	0.4	-0.2	0.0	-0.4	-1.1	-0.7	-0.9	0.3	-0.8	-1.0	-0.7	-1.0	-0.1	-0.2	0.2	0.6
LDL Cholesterol	0.1	0.1	0.4	-0.1	0.2	-0.1	-0.3	-0.4	-0.3	0.4	-0.6	0.5	0.1	0.4	0.1	-0.1	0.1	-0.2	-0.1
Lupus	0.2	0.2	0.8	0.9	0.4	0.7	0.4	-0.4	-0.6	-0.4	-0.2	-0.4	-0.2	-0.0	-0.5	-0.0	0.0	-0.4	0.8
Neuroticism (2016)	3.4	5.0	13.3	-3.4	-2.7	-3.6	-2.0	-0.8	-1.4	-1.3	0.9	-0.8	-1.5	-1.7	-1.1	-2.3	-2.2	2.8	-3.6
Primary Biliary Cirrhosis	1.1	1.6	5.5	-1.9	-0.8	-2.3	-1.3	0.4	-0.4	0.0	0.8	0.3	-0.9	-0.4	-0.1	-1.7	-1.4	1.3	-2.3
Rheumatoid Arthritis	0.9	1.2	2.7	-0.1	-0.8	-0.2	-1.3	-1.6	-0.3	-1.5	-0.4	-1.5	-0.7	-1.6	-1.6	-1.2	-1.1	0.9	0.2
Schizophrenia (2014)	0.3	0.6	3.2	-0.5	-0.7	-0.6	-1.8	-1.0	-0.7	-0.5	-0.2	-0.0	-0.5	-0.5	-0.7	-0.7	-1.0	0.7	-0.6
Triglycerides	0.6	0.9	1.6	0.8	1.1	0.8	0.8	1.1	-0.0	1.3	-0.4	1.2	1.1	0.9	1.2	0.9	1.1	-0.9	0.6
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.7	-0.9	-0.0	-0.8	0.2	1.3	0.3	0.9	0.2	1.3	0.7	0.2	0.9	0.3	0.1	0.4	-1.1
Ulcerative Colitis	1.5	2.2	6.1	-2.2	-1.6	-2.0	-1.5	-0.6	-2.1	-0.7	0.2	-0.2	-1.2	-0.3	-0.4	-1.8	-1.5	1.4	-2.5
Blood Eosinophil Count	0.6	4.7	7.7	1.4	2.0	1.8	2.1	2.6	2.1	2.5	2.2	2.5	2.8	2.7	2.7	1.1	2.0	-2.3	1.0
Blood Platelet Count	0.3	3.3	5.7	1.6	2.3	1.2	2.4	2.0	2.4	2.1	0.9	1.6	1.3	0.9	1.7	2.2	2.3	-1.5	1.6
Blood Red Count	0.0	0.4	1.6	-0.2	-0.6	0.2	0.7	0.6	1.0	-0.2	1.3	-0.6	0.5	-0.7	-0.2	0.3	0.1	0.6	-0.1
Blood White Count	1.1	8.5	16.3	1.5	3.1	1.6	3.5	3.5	2.9	4.0	1.3	3.6	2.4	2.9	3.7	3.2	3.6	-2.4	0.8
Heel T-Score	0.3	2.3	7.2	2.0	-0.3	2.0	1.7	0.0	1.0	-1.5	-1.7	-2.6	-1.2	-0.8	-1.0	1.5	0.2	-0.7	2.7
BMI	0.5	2.6	10.1	-2.7	-1.5	-2.8	-1.2	0.3	-1.5	-0.1	0.2	0.4	-0.6	-0.3	-0.2	-2.0	-1.6	1.7	-3.2
Height	0.1	1.9	6.3	-2.3	-1.3	-1.7	-0.3	0.6	-1.7	-0.5	-1.5	-0.2	-0.5	-0.1	-0.1	-1.9	-1.5	1.2	-2.5
Waist Hip Ratio (WHR)	0.1	0.3	2.1	0.3	0.2	-0.2	0.2	0.3	1.4	0.0	-0.3	-0.2	-0.4	-0.8	-0.3	0.3	0.1	0.3	0.5
Systolic Blood Pressure	0.0	0.2	0.5	-0.6	-0.7	-0.6	0.3	-0.2	0.3	-0.4	-0.5	-0.4	-0.4	-0.3	0.0	-0.1	-0.3	0.5	-0.6
Smoking Status	0.2	0.4	1.2	-0.9	-0.2	-0.9	-0.3	0.1	0.7	0.3	1.1	0.3	-0.5	-0.6	0.2	-0.4	0.0	0.9	-0.7
Allergy or Eczema	0.1	0.4	0.9	-0.8	-0.8	-0.7	-0.6	-0.3	-0.2	-0.6	0.7	-0.5	0.0	-0.4	-0.4	-0.8	-1.0	0.7	-0.8
Cardiovascular Disease	1.1	3.7	9.4	-0.1	1.4	0.2	2.1	2.9	1.9	2.9	1.1	2.7	1.9	1.9	3.1	1.3	1.9	-0.9	-0.6
Hypothyroidism (self reported)	0.2	0.5	1.8	-0.7	-0.2	-0.9	-0.5	-0.3	-0.6	-0.3	1.3	-0.2	-0.3	-0.8	-0.3	-1.0	-0.7	0.8	-0.7
Respiratory disease	1.1	2.4	5.3	1.5	1.4	2.0	2.1	1.9	1.3	1.1	1.5	0.7	2.3	1.0	1.6	1.3	1.4	-1.3	1.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.2	-1.3	-0.9	-1.2	-0.3	0.1	-0.3	-0.3	-0.3	-0.3	-0.4	-0.4	-0.1	-0.6	-0.8	1.0	-1.5
Lung FEV1/FVC ratio	1.0	5.0	9.1	-2.9	-2.4	-2.9	-3.0	-1.6	-1.2	-1.5	-0.2	-0.8	-2.0	-2.2	-1.8	-2.3	-2.6	2.9	-2.8
Lung FVC	0.3	1.6	4.9	0.6	0.4	1.0	2.0	2.2	1.6	0.7	1.8	0.3	1.6	1.2	1.2	0.9	0.9	-1.1	0.4
Neuroticism	0.4	1.0	2.9	-0.6	-1.3	-0.7	-1.5	-1.7	-0.4	-1.1	-0.5	-0.9	-0.4	-1.2	-1.1	-0.8	-1.1	1.0	-0.8
Chronotype (morning person)	0.8	1.9	3.7	-1.5	-1.4	-1.9	-0.7	-0.7	-1.5	-1.4	-0.2	-1.5	-1.5	-1.7	-1.3	-1.3	-1.3	1.7	-1.4
Hair Pigment	0.2	6.7	20.5	4.2	2.7	3.9	2.4	0.7	3.1	0.8	-0.2	-0.1	1.5	0.8	0.8	3.3	2.7	-2.8	4.5
Tanning	0.0	0.5	4.0	-0.6	-0.2	-0.5	0.4	1.2	0.4	0.5	2.0	0.6	0.5	0.5	0.6	-0.4	0.0	0.1	-0.7
Hand grip strength (left)	0.1	0.1	0.8	-0.1	-0.2	-0.1	-0.0	0.4	-0.8	-0.0	0.9	0.2	0.2	0.3	-0.1	-0.5	-0.3	-0.1	-0.0
Number of treatments/medications taken	1.9	3.5	7.7	0.8	2.0	0.9	2.7	2.8	1.7	2.4	1.6	1.9	2.2	1.4	2.6	1.6	1.8	-1.2	0.5
Average weekly spirits intake	1.9	2.3	3.7	1.9	1.5	1.9	1.3	0.7	1.9	1.0	1.7	0.6	0.9	1.4	1.0	1.9	1.6	-1.9	1.9
Sensitivity / hurt feelings	0.2	0.3	0.8	-0.5	-0.9	-0.2	-0.4	-0.8	0.5	-0.7	0.2	-0.6	-0.3	-0.7	-0.6	-0.3	-0.7	0.7	-0.2
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.7	-0.2	-0.6	0.0	-0.2	0.0	0.8	-0.3	0.2	-0.5	-0.6	-0.4	-0.4	-0.0	-0.3	0.4	0.0
Hearing difficulty/problems: Yes	12.8	19.6	41.9	-5.9	-4.2	-6.3	-5.3	-2.8	-5.3	-2.2	-2.8	-0.6	-3.6	-2.0	-2.6	-6.0	-4.9	4.4	-6.5
Relative age of first facial hair	0.6	1.1	6.6	-0.1	-0.7	-0.1	-1.7	-2.6	-1.1	-1.3	-1.0	-1.1	-0.6	-0.4	-1.3	-0.6	-0.8	0.2	-0.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.9	-0.2	0.3	0.0	0.4	0.5	0.1	0.2	-1.0	0.1	0.2	-0.2	-0.2	0.1	0.1	0.2	-0.1
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.3	1.0	0.8	1.4	0.4	-0.7	0.4	-0.1	-1.5	-0.3	0.0	0.1	-0.1	0.5	0.5	-0.7	1.5
Ever had hysterectomy (womb removed)	0.5	0.6	2.6	0.6	0.4	0.9	1.1	0.4	1.6	0.5	-0.5	0.2	0.9	0.3	0.3	0.8	0.8	-0.6	0.8
Systolic blood pressure, automated reading	0.4	1.2	3.3	-0.5	-1.2	-0.8	-0.6	-1.3	0.3	-1.5	-0.4	-1.8	-1.8	-1.4	-1.2	-0.5	-0.9	1.0	-0.2
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	3.3	0.8	1.1	1.3	1.0	0.9	1.1	1.2	-1.8	1.1	1.8	1.5	1.2	1.6	1.3	-1.2	0.6
Angina	0.6	0.8	2.5	1.5	0.9	1.6	0.3	-0.2	1.3	0.3	-0.6	0.2	0.8	0.1	0.1	0.7	0.5	-0.8	1.5
Medication for hormone replacement therapy	0.2	0.3	0.9	0.6	0.2	0.8	0.2	-0.2	-0.2	0.2	-0.2	0.3	0.8	0.9	0.3	0.6	0.4	-0.8	0.5
Vitamin and mineral supplements	1.0	1.4	2.7	-1.2	-1.2	-1.2	-0.9	-1.3	-1.0	-1.0	-1.0	-1.3	-1.4	-1.6	-1.2	-0.6	-0.8	1.6	-0.8
Supplements: Zinc	0.2	0.2	1.5	0.2	0.2	0.2	-0.1	0.5	-0.0	0.3	-0.1	0.6	1.2	0.5	0.3	0.1	0.1	-0.4	0.2
Medication: Co-codamol	1.2	1.3	2.8	1.2	1.3	1.4	1.5	0.7	1.7	0.8	0.0	0.5	1.1	0.8	0.9	1.6	1.2	-1.2	1.3
Medication: Metformin	0.2	0.3	0.9	0.6	0.7	0.5	0.9	0.5	0.4	0.3	-0.9	0.1	0.0	-0.1	0.6	0.8	0.5	-0.3	0.6
Diabetes (father)	1.4	1.8	3.9	-2.0	-1.2	-1.9	-1.3	-0.6	-1.5	-0.5	0.1	-0.3	-1.3	-1.3	-0.4	-1.7	-1.4	1.8	-1.9
Diabetes (mother)	0.8	1.1	2.1	0.8	1.1	0.7	1.1	1.3	0.8	1.4	0.0	1.4	0.9	0.8	1.4	1.1	1.2	-0.8	0.7
Severe depression (siblings)	0.1	0.1	0.4	0.1	-0.2	-0.1	-0.4	-0.3	0.4	-0.4	-0.4	-0.3	-0.4	-0.6	-0.5	-0.1	-0.3	0.3	0.5
Pack years adult smoking proportion	1.3	2.0	5.6	0.2	1.1	0.3	1.1	1.6	1.0	1.9	1.8	2.1	1.2	2.4	1.7	0.7	1.1	-1.3	-0.6
Impedance of leg (right)	0.6	2.9	4.0	1.9	1.6	1.8	1.1	1.3	2.0	1.8	0.8	1.8	1.8	2.0	1.5	1.9	1.9	-2.0	1.6
Leg fat-free mass (left)	0.4	2.4	4.9	-2.1	-1.6	-2.0	-0.8	-0.4	-2.2	-1.1	-0.6	-0.9	-1.2	-1.1	-0.8	-2.1	-1.9	1.6	-2.2
Trunk fat percentage	0.2	0.7	3.4	-1.4	-0.3	-1.5	-0.4	0.8	0.0	0.7	0.2	1.0	0.3	0.3	0.6	-0.9	-0.6	0.5	-1.9
Hand grip strength (right)	0.0	0.1	0.4	-0.2	-0.2	-0.3	-0.3	0.1	-0.7	-0.4	0.7	-0.3	-0.3	-0.2	-0.4	-0.4	-0.5	0.2	-0.2
Townsend deprivation index at recruitment	0.2	0.3	1.0	-0.6	-0.4	-0.3	-0.5	-0.3	-0.8	0.0	-0.5	0.5	-0.0	0.9	-0.1	-0.8	-0.3	-0.0	-1.0
Current tobacco smoking	0.1	0.2	0.9	-0.5	-0.0	-0.3	-0.4	0.2	0.1	0.8	0.3	1.0	0.4	0.7	0.5	-0.2	0.3	0.0	-0.8
Average weekly fortified wine intake	0.1	0.1	0.3	0.1	0.6	0.1	-0.3	-0.2	-0.6	0.4	-0.5	0.6	-0.3	0.2	0.3	0.2	0.2	-0.3	0.1
Maternal smoking around birth	0.1	0.2	0.6	-0.5	-0.2	-0.3	0.6	0.6	-0.3	0.3	0.8	0.2	-0.4	0.1	0.3	0.1	0.1	0.2	-0.6
Fed-up feelings	0.3	0.5	1.7	-0.7	-0.6	-0.7	-1.3	-1.0	-0.7	0.1	-0.4	0.7	-0.5	0.0	-0.0	-0.8	-0.5	0.4	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.2	0.3	-0.0	0.5	0.7	0.5	1.1	0.2	0.5	0.3	0.5	0.8	0.2	0.8	0.3	-0.5	0.2
Relative age voice broke	0.6	0.9	2.4	0.7	1.0	0.8	0.3	0.1	1.4	0.9	-1.2	1.1	1.6	1.2	0.9	0.7	0.9	-1.1	0.4
Taking other prescription medications	0.8	1.2	3.0	0.8	1.3	0.8	1.4	1.4	1.4	1.1	1.7	0.8	0.8	0.3	1.3	0.7	0.8	-0.7	0.9
Age when periods started (menarche)	0.1	0.2	0.6	-0.4	-0.5	-0.1	-0.5	-0.8	-0.1	-0.4	-0.7	-0.2	-0.3	0.7	-0.2	-0.2	-0.3	-0.2	-0.4
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	4.6	0.6	0.2	0.9	1.1	-0.1	2.2	-0.5	0.2	-1.1	-0.2	-0.8	-0.5	0.6	0.4	0.0	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	2.0	0.2	-0.4	0.2	0.9	0.5	1.0	-0.5	-1.4	-0.8	0.0	-0.5	-0.6	0.7	-0.0	0.1	0.6
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.3	-0.7	-0.8	-0.6	-0.5	-0.5	0.3	-0.6	-0.2	-0.8	-0.8	-1.2	-0.8	-0.3	-0.4	1.0	-0.4
Qualifications: CSEs or equivalent	1.5	2.0	5.5	-1.3	-1.7	-1.3	-1.2	-0.8	-2.4	-1.5	1.1	-1.2	-0.8	-1.0	-1.5	-1.8	-1.5	1.3	-1.3
Serious illness, injury or assault to yourself	1.2	1.5	6.5	-1.4	-1.1	-1.0	-0.7	-0.7	-0.3	-0.8	-2.5	-0.7	-0.7	-1.9	-1.1	-0.7	-0.9	1.8	-1.0
High blood pressure	0.5	1.4	4.5	0.2	0.8	0.4	2.1	2.0	2.1	1.3	0.6	0.9	0.5	0.4	1.6	1.0	1.2	-0.4	0.3
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.4	-0.7	-0.8	-0.5	-0.7	-0.6	-1.2	-0.7	1.1	-0.5	-0.0	-0.3	-0.5	-0.8	-0.9	0.5	-0.5
Multivitamins +/- minerals	2.0	2.6	5.5	1.1	1.5	1.5	1.5	1.7	1.2	1.7	1.6	1.9	2.0	2.4	2.0	1.1	1.3	-1.9	0.6
Stomach or abdominal pain in last month	0.3	0.4	1.6	1.0	0.6	0.7	0.3	-0.4	-0.2	-0.0	-0.5	-0.3	-0.9	0.1	-0.2	0.7	0.5	-0.6	1.2
Supplements: Glucosamine	0.3	0.4	1.7	1.1	0.4	0.8	0.3	-0.2	0.9	-0.1	-1.3	-0.3	0.2	0.4	0.0	0.5	0.2	-0.8	1.1
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	11.4	-0.2	0.9	-0.3	1.8	1.9	0.5	1.7	3.4	1.6	0.6	0.8	1.7	0.9	1.1	-0.2	-0.5
Medication: Atenolol	0.1	0.1	0.5	-0.1	-0.1	-0.0	-0.0	0.1	0.7	0.2	0.3	0.0	0.2	0.3	0.3	0.1	-0.0	-0.1	-0.3
Medication: Levothyroxine sodium	0.4	0.7	1.8	-0.3	-0.1	-0.7	-1.1	-1.0	-0.6	-0.6	-1.3	-0.4	-1.1	-1.3	-0.6	-1.2	-0.8	0.8	-0.0
Sitting height	0.1	1.0	3.7	-1.4	-0.3	-0.8	0.7	1.9	-1.2	0.7	0.4	0.8	0.9	0.6	1.2	-0.5	-0.3	0.3	-1.6
Chronic bronchitis/emphysema (father)	0.2	0.3	2.4	-0.2	-0.1	-0.3	-0.4	-0.4	0.5	-0.2	-1.5	-0.2	-0.1	-0.7	-0.6	-0.1	-0.1	0.4	-0.1
High blood pressure (mother)	0.2	0.2	0.7	-0.2	0.5	-0.2	0.5	0.3	0.0	0.7	-0.3	0.7	0.4	0.4	0.8	0.6	0.5	-0.1	-0.3
Body mass index (BMI)	0.4	1.7	4.1	-1.9	-1.3	-2.0	-0.8	-0.2	-0.7	-0.7	-0.8	-0.6	-1.3	-1.0	-0.6	-1.6	-1.4	1.5	-2.0
Impedance of leg (left)	0.9	4.2	7.7	1.9	1.9	1.8	1.5	2.0	2.8	2.2	1.2	2.3	2.2	2.2	2.0	2.2	2.3	-2.2	1.6
Leg predicted mass (left)	0.5	2.4	5.3	-2.1	-1.6	-2.0	-0.8	-0.4	-2.3	-1.1	-0.5	-0.9	-1.2	-1.0	-0.8	-2.1	-1.9	1.6	-2.2
Trunk fat mass	0.3	1.1	5.0	-1.8	-0.6	-1.8	-0.4	0.8	-0.3	0.4	-0.1	0.6	-0.0	-0.1	0.4	-1.4	-1.0	1.0	-2.2
Waist circumference	0.6	2.3	5.2	-2.0	-1.4	-2.3	-1.1	-0.5	-0.5	-1.0	-1.3	-0.9	-1.6	-1.8	-1.1	-1.8	-1.7	2.0	-2.0
Number of incorrect matches in round	0.3	0.5	2.3	1.0	0.2	0.7	1.0	0.2	1.5	-0.2	0.3	-0.6	0.3	-0.7	-0.0	1.0	0.4	-0.2	1.3
Past tobacco smoking	0.4	0.8	2.3	1.2	0.8	1.3	0.3	0.2	0.0	0.6	-0.8	0.8	0.9	1.5	0.4	0.8	0.8	-1.5	0.9
Alcohol usually taken with meals	2.0	3.3	5.5	-1.4	-1.7	-1.4	-2.3	-2.0	-1.9	-2.2	-0.9	-2.0	-1.7	-1.6	-2.3	-1.8	-2.1	1.7	-1.2
Nervous feelings	1.5	2.7	4.5	-1.3	-2.1	-1.5	-1.7	-1.7	-0.8	-2.0	-1.6	-1.9	-1.9	-1.6	-1.8	-1.4	-1.7	1.6	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	3.1	0.5	0.6	0.7	0.8	0.6	1.8	1.0	0.2	0.7	0.2	0.5	1.1	1.0	1.0	-0.6	0.7
Hearing difficulty/problems with background noise	8.2	13.2	25.7	-4.6	-3.5	-4.8	-4.6	-2.7	-4.4	-2.2	-2.0	-1.0	-3.0	-1.9	-2.5	-5.1	-3.9	3.5	-5.0
Hair/balding pattern: Pattern 2	0.4	0.5	1.5	-0.3	0.4	0.0	0.6	1.0	-0.4	0.9	1.2	0.9	0.6	0.9	0.8	0.4	0.6	-0.2	-0.4
Had menopause	3.8	4.8	8.1	-2.9	-2.4	-2.8	-1.5	-1.0	-1.4	-1.9	-0.4	-1.9	-2.5	-2.4	-1.7	-2.6	-2.6	2.8	-2.6
Had other major operations	0.5	0.6	1.6	-1.1	-0.8	-0.9	-0.0	0.4	0.5	-0.5	-0.4	-0.8	0.0	-1.1	-0.4	-0.5	-0.8	1.2	-0.9
Forced vital capacity (FVC)	0.6	2.2	5.6	0.5	0.9	1.1	1.6	2.3	0.6	1.6	1.6	1.7	2.4	2.0	1.8	1.0	1.2	-1.4	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	3.0	0.4	-0.1	0.4	1.0	1.0	1.2	-0.0	-1.7	-0.4	0.1	-0.2	-0.1	0.9	0.3	-0.2	0.7
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	3.0	-0.9	-0.2	-1.0	0.8	1.6	1.7	0.5	1.6	0.4	-0.3	-0.2	0.5	0.2	0.2	0.6	-1.1
Qualifications: None of the above	0.2	0.4	2.4	-0.1	-0.5	-0.2	0.2	0.0	1.3	-0.6	-0.8	-0.8	-1.6	-0.3	-0.3	-0.4	-0.5	0.2	0.2
Financial difficulties in last 2 years	0.1	0.2	1.0	-0.5	-0.4	-0.2	0.6	1.0	0.5	0.0	0.5	-0.1	0.4	0.3	-0.2	-0.1	-0.2	0.2	-0.6
Mouth/teeth dental problems	0.3	0.5	1.5	0.4	0.6	0.7	1.1	1.2	0.1	0.6	-0.1	0.4	0.8	0.3	0.9	0.9	0.8	-0.4	0.5
Heart attack	1.6	2.0	2.9	1.1	1.6	1.3	1.5	1.5	1.2	1.7	1.4	1.5	1.4	1.5	1.6	1.7	1.5	-1.4	0.9
Allergy	0.3	0.6	1.5	-0.9	-0.7	-1.0	-0.9	-0.6	-0.3	-0.3	-1.2	-0.3	-1.1	-0.7	-0.6	-0.7	-0.6	0.9	-1.0
Pain all over the body in last month	3.1	3.4	5.0	2.1	1.9	2.2	1.9	1.3	1.2	1.7	0.9	1.5	1.7	1.9	1.9	2.0	2.1	-2.2	2.2
Diabetes (self-reported)	0.4	0.6	1.1	-0.9	-0.9	-0.8	-0.1	0.1	-0.0	-0.7	-0.1	-0.9	-1.0	-1.0	-0.5	-0.6	-0.9	1.1	-0.8
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.6	-0.3	0.0	0.1	0.2	0.4	-0.2	0.6	0.1	0.8	0.6	0.5	0.6	0.2	0.3	-0.1	-0.3
Medication: Ramipril	1.6	2.1	4.0	1.1	1.4	1.2	2.0	1.6	1.8	1.4	1.3	1.0	1.6	1.1	1.8	1.6	1.5	-1.3	1.0
Medication: Simvastatin	0.4	0.6	1.6	-1.3	-0.1	-1.2	0.0	1.2	0.2	0.8	-1.0	0.8	-0.2	-0.1	1.0	-0.7	-0.3	0.7	-1.2
Fluid intelligence score	0.8	1.6	3.2	-1.0	-1.0	-0.9	-1.8	-1.6	-1.4	-1.3	-1.3	-1.4	-0.4	-1.4	-1.6	-1.1	-1.3	1.3	-0.6
Illnesses of siblings	0.6	0.9	2.3	1.5	0.7	1.5	0.3	-0.2	0.7	0.2	-0.1	0.3	1.1	1.0	0.2	1.0	1.0	-1.4	1.5
Neuroticism score	1.7	3.6	6.3	-1.9	-2.3	-1.9	-2.5	-2.2	-1.5	-1.7	-0.8	-1.4	-1.3	-2.0	-1.8	-2.0	-2.1	2.2	-2.0
Weight	0.6	2.9	7.0	-2.6	-1.8	-2.5	-1.1	-0.3	-1.3	-1.1	-0.9	-0.9	-1.4	-1.3	-0.9	-2.3	-2.1	2.0	-2.6
Impedance of arm (right)	0.2	1.0	2.6	0.9	0.9	0.9	0.1	0.6	-0.1	1.3	1.1	1.6	1.4	1.5	1.0	0.7	0.9	-1.1	0.6
Arm fat percentage (right)	0.2	1.0	4.3	-1.7	-0.7	-1.8	-0.5	0.5	-0.4	0.2	-0.4	0.4	-0.4	-0.3	0.2	-1.2	-0.9	1.1	-2.1
Trunk fat-free mass	0.4	2.4	4.7	-2.0	-1.7	-1.9	-0.7	-0.2	-1.5	-1.5	-1.0	-1.4	-1.6	-1.4	-1.0	-2.2	-2.0	1.7	-1.9
Hip circumference	0.5	2.0	4.0	-1.8	-1.4	-1.9	-1.3	-0.7	-1.4	-1.0	-1.0	-0.8	-1.2	-1.1	-0.9	-2.0	-1.8	1.4	-1.9
Time employed in main current job	0.5	0.6	1.1	0.9	1.0	0.9	1.0	0.7	0.7	0.6	-0.0	0.4	0.4	0.2	0.6	1.0	1.0	-0.7	1.0
Alcohol intake versus 10 years previously	0.2	0.3	0.7	0.3	0.5	0.5	0.3	0.3	0.8	0.6	-0.6	0.9	0.8	0.2	0.6	0.1	0.6	-0.3	0.2
Father’s age at death	0.3	0.4	1.1	-0.2	0.4	-0.1	0.8	1.0	0.5	0.8	0.4	0.7	1.0	1.0	0.9	0.7	0.4	-0.3	-0.5
Worrier / anxious feelings	1.5	2.8	5.2	-2.3	-2.2	-1.9	-1.5	-1.2	-1.4	-1.5	-1.3	-1.3	-1.2	-1.3	-1.4	-1.8	-1.9	2.0	-2.1
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	4.0	-0.4	0.4	0.0	1.2	1.6	2.0	1.2	-0.1	1.1	0.8	0.9	1.2	0.8	0.7	-0.2	-0.6
Falls in the last year	2.0	2.7	4.2	1.8	1.8	1.8	2.0	1.5	1.7	1.3	1.1	1.2	1.0	2.0	1.5	1.8	1.6	-2.0	1.6
Hair/balding pattern: Pattern 3	0.2	0.2	1.0	0.3	-0.1	-0.1	0.0	-0.2	0.8	-0.6	0.8	-0.5	-1.0	-0.4	-0.5	-0.1	-0.4	-0.0	0.4
Number of live births	0.1	0.2	0.7	-0.2	0.3	-0.2	0.3	0.5	-0.4	0.6	-0.4	0.9	0.1	0.6	0.6	0.1	0.2	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.3	-0.2	0.2	0.2	0.8	1.8	0.2	1.1	1.2	1.2	1.6	1.0	1.2	0.3	0.3	-0.4	-0.6
Pulse rate	0.3	0.5	1.7	1.0	0.8	0.8	0.9	0.2	0.5	0.4	0.2	-0.0	-0.5	-0.3	0.1	1.2	1.0	-0.4	1.3
Happiness	0.3	0.4	2.4	-0.6	-0.4	-0.6	-0.2	0.6	1.5	0.2	0.2	0.1	-0.6	-0.8	0.1	-0.1	0.2	0.9	-0.5
Noisy workplace	0.4	0.5	1.6	0.7	0.6	0.8	1.3	1.1	1.2	0.6	0.2	0.3	0.2	0.2	0.6	0.7	0.7	-0.4	0.8
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.0	-0.3	-0.1	-0.2	-0.7	-0.7	-1.0	-0.3	-0.8	-0.3	0.3	-0.1	-0.4	-0.4	-0.3	0.2	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.8	-0.0	0.1	-0.0	0.3	0.2	-0.9	-0.1	-0.2	-0.1	-0.0	-0.1	-0.0	-0.1	-0.2	0.0	-0.1
Mouth/teeth dental problems: Dentures	1.2	2.1	5.2	-1.4	-1.6	-1.8	-1.8	-1.1	-1.8	-1.1	-0.2	-0.4	-1.5	-0.1	-0.9	-2.3	-1.9	1.0	-1.9
Asthma	1.3	2.5	6.2	0.9	1.2	1.4	2.5	2.4	1.4	1.3	1.7	0.8	2.4	1.2	1.6	1.4	1.5	-1.1	1.0
Medication: Ibuprofen (e.g. Nurofen)	3.5	4.4	8.4	1.5	2.1	1.9	2.9	2.0	1.3	2.1	2.7	1.6	2.8	1.5	2.0	2.7	2.4	-1.7	1.5
Medication: Cholesterol lowering	1.4	2.1	5.9	-0.7	1.1	-0.4	0.9	2.1	0.9	2.4	0.1	2.4	2.0	1.4	2.3	0.7	1.1	-0.4	-0.9
Depression (self-reported)	0.4	0.5	2.3	0.8	0.3	0.6	-0.0	-0.5	1.5	-0.3	0.4	-0.7	-0.5	-1.2	-0.3	0.6	0.2	0.3	1.2
Medication: Lansoprazole	0.4	0.5	1.6	0.8	0.1	0.6	-0.3	-1.2	0.0	-0.7	-1.0	-0.9	-0.6	-0.6	-0.6	0.1	-0.0	-0.2	1.2
Prospective memory result	0.3	0.4	1.4	1.0	0.4	0.9	0.3	-0.1	1.2	-0.0	-0.8	-0.2	0.5	-0.2	0.0	0.3	0.4	-0.5	1.2
Lung cancer (father)	0.8	1.0	1.7	-1.3	-1.0	-1.2	-0.6	-0.2	0.2	-0.8	-0.4	-0.7	-1.0	-1.3	-0.8	-1.3	-1.1	1.3	-1.1
Illnesses of mother	0.3	0.3	2.6	-0.1	-0.6	-0.1	-0.7	-0.6	-0.5	-0.5	1.6	-0.3	0.1	-0.3	-0.7	-0.4	-0.4	0.2	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	4.1	0.3	0.6	0.7	1.1	2.0	0.7	1.1	1.5	1.2	1.9	1.0	1.3	0.8	0.6	-0.8	-0.0
Pulse wave Arterial Stiffness index	1.7	2.0	4.9	0.4	1.7	0.5	1.3	1.8	1.3	2.0	1.0	2.0	1.5	1.2	2.2	1.1	1.5	-0.9	0.2
Impedance of arm (left)	0.3	1.5	3.8	1.0	1.1	1.1	0.2	0.6	0.3	1.5	1.1	1.9	2.0	1.8	1.2	1.1	1.1	-1.3	0.6
Arm fat mass (right)	0.5	1.9	5.9	-2.2	-1.3	-2.3	-1.0	0.0	-0.8	-0.5	-0.8	-0.3	-1.0	-1.0	-0.5	-1.8	-1.6	1.6	-2.4
Trunk predicted mass	0.4	2.4	4.5	-2.0	-1.7	-1.9	-0.7	-0.2	-1.5	-1.4	-1.0	-1.3	-1.6	-1.4	-1.0	-2.1	-2.0	1.7	-1.9
Standing height	0.1	1.3	3.2	-1.7	-1.3	-1.4	-0.8	-0.0	-1.4	-0.9	-0.2	-0.6	-0.3	-0.7	-0.6	-1.8	-1.6	1.2	-1.6
Length of working week for main job	0.7	0.7	3.3	-0.9	-1.1	-0.7	0.6	-0.3	-0.3	-0.9	1.8	-1.2	-0.7	-0.7	-0.7	-0.6	-0.5	0.9	-0.5
Exposure to tobacco smoke at home	2.1	2.3	12.3	-1.1	-1.1	-1.1	-1.7	-2.0	-0.4	-1.2	-3.5	-1.1	-1.3	-1.3	-1.5	-1.5	-1.3	1.2	-0.9
Breastfed as a baby	0.2	0.3	1.5	0.3	0.5	0.2	0.7	1.2	1.2	0.3	0.2	0.1	-0.2	-0.3	0.5	0.3	0.1	-0.0	0.4
Tense / ‘highly strung’	0.7	1.2	2.4	-1.4	-1.6	-1.4	-1.0	-0.5	0.5	-0.9	-1.1	-0.9	-0.7	-1.4	-0.9	-0.8	-1.2	1.5	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.3	-0.9	-0.2	-0.8	0.1	1.1	-0.4	0.2	0.6	0.2	-0.6	-0.2	0.3	-0.4	-0.4	0.5	-0.9
Hair/balding pattern: Pattern 4	1.0	2.5	11.4	-1.2	-1.8	-1.0	-1.3	-1.0	-0.3	-1.8	-3.4	-1.8	-1.3	-1.4	-1.7	-1.3	-1.7	1.4	-1.0
Birth weight of first child	2.9	5.2	11.5	-3.2	-2.6	-3.4	-1.8	-1.0	-2.4	-1.6	-0.2	-1.4	-2.0	-1.7	-1.6	-2.7	-2.6	2.7	-3.2
Peak expiratory flow (PEF)	0.3	0.7	2.3	-0.9	-0.3	-0.5	0.5	1.5	0.3	0.7	1.1	0.7	1.2	0.7	0.8	-0.0	-0.2	0.2	-1.4
Pulse wave reflection index	6.8	8.4	14.9	1.6	3.0	1.7	2.5	3.6	2.5	3.6	1.3	3.7	3.9	3.8	3.8	2.2	2.8	-2.9	0.7
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.5	0.2	0.0	0.2	0.3	0.4	0.6	0.0	0.7	-0.1	0.0	0.3	0.1	0.0	0.0	-0.2	0.2
Loud music exposure frequency	0.2	0.2	0.8	-0.4	-0.5	-0.4	-0.0	0.6	0.4	-0.1	0.9	-0.1	-0.2	0.0	0.1	-0.5	-0.4	0.3	-0.5
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.6	-0.9	-0.9	-0.4	-1.4	-1.4	-1.9	-0.8	-1.7	-0.3	0.3	-0.0	-1.0	-1.3	-0.7	0.6	-0.9
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	2.1	-0.4	-0.9	-0.5	-0.7	-1.4	-0.1	-1.1	-0.8	-1.2	-0.7	-0.9	-1.4	-0.3	-0.6	0.7	-0.3
Blood clot in the leg (DVT)	2.2	2.8	6.1	2.2	1.9	1.9	1.7	1.2	2.5	1.2	1.0	0.9	1.0	1.0	1.4	2.0	1.8	-1.8	2.2
Medication: Paracetamol	0.4	0.6	1.1	1.1	1.1	1.0	0.6	0.4	1.0	0.7	-0.1	0.5	0.2	0.9	0.6	0.8	0.9	-1.0	1.0
Headache pain in last month	0.9	1.5	5.4	1.1	1.2	1.0	1.6	1.5	0.5	1.0	2.3	0.9	1.0	1.0	1.0	1.4	1.2	-1.1	0.8
Medication for cholesterol, blood pressure or diabetes	2.3	3.8	9.5	0.1	-1.7	-0.2	-2.0	-3.1	-1.7	-2.9	-1.0	-2.7	-2.6	-1.9	-3.1	-1.1	-1.6	1.0	0.7
Glaucoma (self-reported)	0.7	0.9	3.9	-0.3	0.6	-0.2	0.4	1.0	-1.0	1.5	0.3	2.0	1.2	1.0	1.2	0.4	0.7	-0.3	-0.7
Gout (self-reported)	1.8	2.5	5.5	-0.2	-1.3	-0.4	-1.6	-2.2	-1.1	-2.3	-1.2	-2.3	-1.3	-2.1	-2.3	-1.4	-1.5	1.1	0.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.9	-0.7	-0.2	-1.0	-0.8	-0.6	-0.5	-0.4	0.6	-0.3	-0.8	-1.4	-0.4	-1.2	-0.8	1.1	-0.4
Medication: Amlodipine	0.6	0.8	2.5	0.4	0.8	0.6	1.1	0.9	1.6	0.9	0.8	0.9	1.2	1.0	0.9	0.7	0.9	-0.8	0.2
Medication: Ventolin 100micrograms inhaler	4.1	5.3	11.9	1.3	1.7	1.4	2.9	3.5	1.4	2.6	2.7	2.3	2.8	2.6	3.0	1.9	2.3	-2.0	0.9
Birth weight	0.7	1.6	2.8	-0.8	-1.1	-0.8	-1.3	-1.2	-1.5	-1.5	0.2	-1.3	-1.0	-1.7	-1.6	-1.7	-1.5	1.3	-0.4
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.6	0.5	0.0	0.5	0.2	-0.5	-0.4	-0.4	-0.7	-0.5	-0.7	0.4	-0.3	0.0	0.0	-0.4	0.4
High blood pressure (siblings)	0.1	0.1	0.5	-0.4	0.2	-0.4	0.4	0.7	-0.4	0.4	-0.4	0.3	-0.4	-0.1	0.5	-0.1	-0.2	0.3	-0.4
Forced vital capacity (FVC), Best measure	0.7	2.7	6.5	0.9	1.1	1.4	2.0	2.6	1.1	1.6	1.5	1.5	2.5	1.8	1.9	1.4	1.3	-1.5	0.6
Body fat percentage	0.2	0.7	3.1	-1.3	-0.2	-1.4	-0.2	0.9	0.3	0.8	0.0	1.0	0.2	0.2	0.6	-0.8	-0.5	0.5	-1.8
Leg fat percentage (right)	0.1	0.4	1.6	-0.9	-0.2	-1.0	0.1	1.0	0.6	0.7	-0.5	0.7	-0.0	0.2	0.6	-0.6	-0.3	0.4	-1.3
Arm fat-free mass (right)	0.3	1.5	3.2	-1.8	-1.3	-1.6	-0.4	-0.1	-0.9	-1.0	-0.7	-0.9	-1.1	-1.2	-0.7	-1.6	-1.5	1.5	-1.7
Exposure to tobacco smoke outside home	0.8	1.0	3.1	-1.4	-0.9	-1.1	-0.9	-0.9	-1.8	-0.3	-1.4	0.1	-0.9	-0.2	-0.4	-1.2	-0.9	0.8	-1.3
Comparative body size at age 10	0.4	1.0	3.4	-1.3	-0.3	-1.2	-0.4	0.9	-1.0	0.9	0.9	1.6	0.5	1.2	1.2	-0.9	-0.5	0.1	-1.8
Number of full brothers	0.6	0.7	3.2	-0.7	-0.8	-0.6	-1.1	-1.3	-1.0	-0.7	-0.1	-0.6	-1.8	-0.5	-0.7	-0.5	-0.5	0.8	-0.5
Worry too long after embarrassment	1.2	1.9	3.5	-1.2	-1.9	-0.9	-1.7	-1.6	-0.7	-1.6	-0.6	-1.7	-0.5	-1.5	-1.7	-1.3	-1.7	1.5	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.4	3.3	0.9	1.2	1.0	1.1	1.4	0.9	1.3	1.8	1.2	0.9	0.9	1.4	1.3	1.0	-1.0	0.7
Wheeze or whistling in the chest in last year	1.0	1.9	5.6	0.5	0.7	0.8	2.0	2.4	1.7	1.5	2.3	1.0	0.8	0.8	1.7	0.9	1.2	-0.7	0.6
Number of children fathered	0.2	0.2	1.0	-0.3	-0.2	-0.3	0.0	0.2	0.9	-0.1	-0.1	-0.3	0.1	-1.0	-0.2	0.4	0.1	0.7	0.1
Reason for reducing amount of alcohol drunk: Health precaution	3.1	3.6	8.5	-0.9	-1.8	-1.1	-1.3	-2.1	-1.0	-2.7	-1.4	-2.9	-1.8	-2.7	-2.5	-1.6	-2.0	1.9	-0.4
Age at first live birth	0.3	0.6	2.7	-1.2	-0.5	-1.1	-0.3	0.8	-1.6	0.2	0.2	0.4	0.1	0.4	0.3	-0.6	-0.6	0.5	-1.5
Pulse wave peak to peak time	1.8	2.1	4.9	-0.5	-1.8	-0.5	-1.4	-1.8	-1.4	-2.1	-1.0	-2.0	-1.5	-1.1	-2.2	-1.2	-1.6	0.9	-0.3
Health satisfaction	1.1	1.4	4.7	-0.1	0.8	-0.1	1.3	2.2	1.2	1.7	1.5	1.6	0.6	0.8	1.5	1.2	1.2	-0.3	-0.2
Shortness of breath walking on level ground	0.5	0.6	3.2	0.0	0.4	0.1	0.8	1.4	1.8	0.9	1.1	0.6	0.3	0.5	0.8	0.5	0.6	-0.3	0.1
Qualifications: College or University degree	0.2	0.7	2.3	0.1	0.8	0.2	-0.2	0.9	-0.1	1.3	-0.1	1.5	1.2	1.4	0.9	0.4	0.7	-0.7	-0.3
Eye problems/disorders: None of the above	1.0	1.2	2.2	-0.7	-1.0	-0.9	-1.2	-1.5	-0.2	-1.3	-0.1	-1.3	-1.4	-1.3	-1.2	-1.4	-1.0	1.0	-0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.8	-0.7	-0.2	-0.9	-0.5	-0.2	-0.5	0.0	0.7	0.1	-0.6	-0.3	-0.1	-0.6	-0.4	0.6	-0.9
Emphysema/chronic bronchitis	4.1	4.6	7.1	2.0	2.2	2.0	2.5	1.9	1.6	2.0	2.3	1.8	2.7	2.3	2.2	2.1	2.3	-2.3	1.8
Medication for pain relief, constipation, heartburn	1.2	2.1	3.7	-1.3	-1.7	-1.5	-1.9	-1.5	-1.8	-1.4	-0.9	-0.8	-1.2	-0.9	-1.4	-1.9	-1.6	1.2	-1.4
Neck or shoulder pain in last month	0.3	0.5	0.9	-0.7	-0.5	-0.5	-0.2	-0.4	-0.9	-0.7	0.5	-0.9	-0.9	-0.9	-0.7	-0.7	-0.9	0.8	-0.5
Medication: Blood pressure	2.0	3.6	7.2	1.2	1.8	1.2	2.4	2.7	2.3	2.3	1.0	1.9	2.1	1.4	2.5	1.7	2.1	-1.5	0.9
Angina (self-reported)	0.4	0.5	1.6	1.2	0.7	1.3	0.3	-0.2	1.2	0.2	-0.6	0.0	0.7	-0.1	0.0	0.6	0.3	-0.6	1.2
Migraine (self-reported)	0.9	1.1	3.4	1.1	0.9	1.2	1.8	1.5	1.6	0.3	1.2	-0.1	0.4	0.0	0.4	1.1	0.9	-0.6	1.1
Medication: Ibuprofen	2.0	2.4	5.1	1.2	1.5	1.5	2.2	1.3	0.7	1.4	2.1	1.0	2.2	0.9	1.3	2.3	1.8	-1.1	1.2
Medication: Allopurinol	0.4	0.6	1.4	0.8	0.1	0.6	-0.8	-1.2	-0.0	-1.0	-0.5	-1.0	0.0	-1.0	-1.0	-0.3	-0.3	0.1	1.1
Medication: Omeprazole	0.1	0.2	0.7	0.0	-0.4	0.0	-0.0	-0.1	-0.3	-0.6	-0.2	-0.8	-0.9	-0.4	-0.4	-0.4	-0.4	0.2	0.3
Medication: Seretide 50 evohaler	4.9	5.6	12.3	1.9	2.1	2.2	3.5	3.1	1.4	2.2	2.8	1.7	2.5	2.6	2.5	2.1	2.3	-2.4	1.7
Mean time to correctly identify matches	0.8	1.5	2.7	-1.5	-1.2	-1.5	-1.2	-1.0	-0.2	-1.2	-1.4	-1.0	-1.4	-0.8	-0.9	-1.7	-1.2	1.2	-1.5
Heart disease (mother)	0.9	1.1	3.8	-1.5	-0.4	-1.4	-1.0	0.4	-0.2	0.8	-1.7	1.3	-0.1	0.7	0.9	-1.1	-0.6	0.5	-1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.5	-0.5	-0.2	-0.3	0.4	0.4	-0.1	-0.3	0.6	-0.3	0.0	-0.2	-0.1	-0.7	-0.3	0.3	-0.6
Whole body fat mass	0.3	1.1	4.9	-1.8	-0.8	-1.9	-0.4	0.7	-0.4	0.2	-0.4	0.4	-0.2	-0.3	0.2	-1.4	-1.1	1.1	-2.2
Leg fat mass (right)	0.3	1.0	4.4	-1.7	-0.9	-1.8	-0.2	0.8	-0.1	0.1	-0.5	0.1	-0.5	-0.3	0.1	-1.3	-1.1	1.0	-2.1
Arm predicted mass (right)	0.2	0.9	2.4	-1.6	-1.0	-1.4	0.0	0.4	-0.6	-0.6	-0.4	-0.6	-0.7	-0.8	-0.2	-1.2	-1.1	1.1	-1.5
Pulse rate, automated reading	2.4	7.6	12.4	2.7	2.7	2.7	3.5	3.2	3.0	2.6	2.4	2.0	2.3	2.7	2.7	3.2	3.0	-2.8	2.3
Alcohol intake frequency.	0.2	0.5	1.6	-0.6	-0.5	-0.7	-0.0	0.0	1.2	-0.4	-1.3	-0.6	-0.6	-1.1	-0.5	-0.1	-0.5	1.0	-0.6
Comparative height size at age 10	0.9	4.7	8.5	-2.4	-2.3	-2.4	-2.1	-1.4	-2.4	-2.1	-1.7	-1.6	-1.8	-1.8	-1.8	-2.9	-2.8	2.2	-2.3
Number of full sisters	1.3	1.6	3.6	-1.3	-1.3	-1.1	-1.3	-1.3	-1.9	-1.2	0.0	-1.0	-1.3	-1.0	-1.2	-1.4	-1.4	1.3	-1.2
Suffer from ‘nerves’	2.0	3.1	5.3	-1.5	-2.3	-1.7	-2.0	-1.6	-1.5	-2.0	-1.4	-1.8	-1.5	-1.7	-1.8	-1.6	-2.2	1.8	-1.7
Overall health rating	1.2	2.6	5.9	0.9	1.5	1.0	2.4	2.4	2.4	1.9	0.9	1.5	0.7	1.3	1.8	1.8	1.7	-1.2	1.0
Chest pain or discomfort	0.4	0.6	1.5	-0.9	-0.5	-1.1	-0.9	-0.8	0.3	-0.4	-0.3	-0.6	-1.2	-1.1	-0.6	-0.4	-0.8	1.1	-0.6
Had major operations	0.7	0.8	3.4	0.1	0.7	0.0	0.9	1.8	1.0	1.5	-0.4	1.3	0.3	0.4	1.2	0.7	1.0	-0.2	0.2
Age at last live birth	0.9	1.3	3.6	-0.6	0.6	-0.4	0.6	1.9	-0.4	1.6	1.1	1.9	1.4	1.5	1.6	0.2	0.7	-0.5	-1.1
Family relationship satisfaction	0.4	0.5	1.3	-0.2	0.3	-0.1	0.8	1.1	0.9	1.0	1.1	0.8	0.6	0.4	0.9	0.5	0.7	-0.0	-0.1
Leg pain on walking	0.5	0.6	3.3	-0.8	-0.7	-0.7	0.3	-0.1	1.8	-0.6	-0.3	-0.8	-1.2	-0.9	-0.8	0.3	-0.3	0.8	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.5	0.0	-0.1	-0.2	-0.5	-0.7	0.3	-0.2	-0.6	-0.1	-0.2	-0.2	-0.1	-0.4	-0.0	0.1	-0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.3	0.6	0.2	0.6	0.6	0.0	0.8	-0.6	-0.1	-1.1	-0.3	-0.6	-0.4	0.0	-0.0	-0.1	0.9
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.5	-0.7	-0.9	-0.8	-1.4	-1.5	-1.6	-1.1	-0.2	-0.9	-1.4	-0.5	-1.0	-1.2	-0.9	0.6	-0.6
Medication: Aspirin	2.4	3.2	9.5	1.7	2.1	1.9	1.8	1.5	3.1	1.8	-0.1	1.3	1.9	1.1	1.5	2.2	1.8	-1.6	1.6
Supplements: Vitamin C	0.5	0.5	1.4	0.9	0.6	0.8	0.9	1.1	1.2	0.2	-0.3	0.3	0.2	0.7	0.2	0.6	0.6	-1.0	1.0
Knee pain experienced in last month	0.4	0.6	2.1	-0.4	-0.7	-0.4	0.4	-0.1	0.8	-1.1	0.8	-1.4	-1.1	-1.2	-0.9	-0.1	-0.7	0.8	-0.2
Hypertension (Self-reported)	0.7	2.1	5.6	0.5	1.1	0.8	2.2	2.3	2.4	1.7	0.8	1.3	1.0	0.7	1.9	1.3	1.5	-0.7	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.3	-0.6	-0.7	-0.4	-0.2	-0.1	-0.4	-0.2	-1.2	-0.3	-0.4	-0.3	0.0	-0.3	-0.4	0.5	-0.3
Illnesses of father: Heart disease	0.6	0.9	2.3	-0.4	0.6	-0.1	0.7	1.5	-0.8	1.3	1.5	1.4	0.4	1.0	1.4	0.3	0.6	-0.3	-0.5
Illnesses of siblings: Diabetes	0.3	0.4	1.7	-0.5	-0.3	-0.6	0.0	0.2	0.1	-0.5	0.6	-0.8	-0.8	-1.3	-0.5	-0.3	-0.4	0.9	-0.3
Smoking status: Previous	0.6	0.9	2.3	-1.2	-0.9	-1.4	-0.2	-0.1	-0.0	-0.7	0.8	-0.9	-1.2	-1.5	-0.5	-0.9	-0.9	1.5	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.9	0.1	-0.2	-0.0	-0.2	-0.3	-1.0	-0.6	-0.6	-0.5	-0.8	0.0	-0.4	-0.3	-0.3	-0.1	0.3
Whole body fat-free mass	0.3	2.0	3.9	-1.9	-1.5	-1.8	-0.6	-0.2	-1.7	-1.2	-0.6	-1.1	-1.4	-1.2	-0.8	-2.0	-1.8	1.5	-1.8
Leg fat-free mass (right)	0.4	2.0	4.3	-2.0	-1.4	-2.0	-0.7	-0.2	-2.0	-0.9	-0.3	-0.7	-1.1	-1.0	-0.7	-2.0	-1.7	1.6	-2.1
Arm fat percentage (left)	0.2	0.9	4.3	-1.6	-0.6	-1.7	-0.5	0.6	-0.3	0.4	-0.3	0.6	-0.1	-0.1	0.3	-1.1	-0.8	1.0	-2.1
Average weekly red wine intake	0.2	0.3	1.2	-0.1	-0.4	0.2	-0.0	-0.6	0.8	-0.6	-0.5	-1.1	-0.0	-0.3	-0.9	0.2	-0.2	0.2	0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	2.4	0.4	0.1	0.2	-0.1	-0.1	-0.1	0.0	-1.5	0.2	0.5	0.2	0.1	-0.2	-0.1	-0.4	0.3
Mood swings	0.8	1.5	5.0	-1.8	-1.2	-1.9	-1.5	-0.6	-1.5	-0.1	-0.1	0.3	-0.4	-0.7	-0.4	-1.5	-1.0	1.4	-2.2
Loneliness, isolation	0.9	1.3	2.6	-1.5	-1.2	-1.3	-1.3	-0.7	-0.3	-0.7	0.4	-0.5	-1.6	-1.1	-0.7	-1.2	-1.2	1.5	-1.5
Long-standing illness, disability or infirmity	1.0	1.6	3.8	0.3	1.4	0.6	1.5	1.9	1.8	1.9	-0.8	1.6	1.2	0.3	1.4	1.1	1.3	-0.3	0.4
Ever had bowel cancer screening	0.3	0.3	1.0	0.0	-0.2	-0.2	-0.6	-0.9	-0.5	-0.7	-0.4	-0.9	-0.1	-1.0	-0.8	-0.4	-0.5	0.5	0.1
Diabetes diagnosed by doctor	0.3	0.4	1.1	-1.0	-0.7	-0.9	0.1	0.5	-0.5	-0.4	-0.1	-0.6	-0.6	-0.8	-0.2	-0.4	-0.7	1.0	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	2.1	0.4	0.8	0.4	0.9	1.5	0.4	1.4	1.2	1.4	1.3	1.1	1.3	0.6	0.9	-0.8	0.1
Friendships satisfaction	0.2	0.3	0.7	-0.6	-0.1	-0.8	-0.4	0.5	0.0	0.6	-0.5	0.7	-0.5	-0.1	0.5	-0.3	-0.0	0.5	-0.8
Qualifications: nursing, teaching	0.7	1.1	3.2	1.0	-0.4	0.9	-0.9	-1.8	-0.5	-1.2	-1.7	-1.2	-0.4	-0.8	-1.6	-0.1	-0.4	-0.1	1.3
Commuting to job workplace: Walk	0.2	0.2	1.3	-0.2	-0.1	0.0	-0.3	-0.6	-1.1	-0.3	-0.6	-0.2	-0.5	-0.0	-0.3	-0.3	-0.3	0.2	-0.2
Eye problems/disorders: Cataract	2.1	2.4	5.4	1.0	1.5	1.2	1.9	2.3	1.6	1.8	0.7	1.5	2.0	1.3	1.9	1.5	1.4	-1.3	1.0
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.7	0.9	0.8	0.9	0.6	-0.3	0.7	0.2	0.7	-0.2	-0.1	-0.1	-0.2	1.1	0.7	-0.5	1.3
Medication for cholesterol	0.6	1.0	1.8	-0.9	-1.1	-1.1	-0.9	-0.6	-0.3	-1.2	-0.1	-1.0	-1.2	-1.1	-1.3	-1.1	-1.0	1.1	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.2	0.2	0.5	-0.1	0.1	0.4	-0.1	0.2	0.4	0.2	-0.3	-0.0	0.4	0.2	0.1	-0.1	0.3
Back pain experienced in last month	0.9	1.4	3.7	-0.9	-1.1	-1.2	-0.8	-0.9	0.2	-1.2	-0.6	-1.3	-1.9	-1.6	-1.2	-1.1	-1.3	1.3	-0.7
Mineral and other dietary supplements	0.4	0.5	2.4	-0.5	0.5	-0.3	-0.1	0.7	-0.4	1.2	0.2	1.6	0.7	0.6	0.9	0.2	0.8	-0.0	-0.7
Breast cancer (self-reported)	1.7	2.0	4.4	-0.7	-1.6	-0.6	-1.6	-2.0	-0.3	-1.9	-0.6	-2.1	-0.9	-1.5	-2.0	-1.2	-1.6	1.2	-0.3
Asthma (self-reported)	1.1	2.1	6.0	0.8	1.0	1.2	2.3	2.3	1.1	1.2	1.8	0.7	2.5	1.0	1.5	1.1	1.3	-1.0	0.9
Osteoporosis (self-reported)	0.2	0.2	0.7	0.1	0.9	0.1	-0.2	0.1	-0.3	0.6	0.6	0.7	0.5	0.5	0.4	0.1	0.4	-0.4	0.2
Osteoarthritis (self-reported)	0.6	0.8	2.6	-0.3	-0.6	-0.3	-0.6	-1.5	-0.2	-0.9	-0.8	-1.0	-1.6	-1.6	-1.0	-0.2	-0.5	1.0	0.1
Medication: Aspirin	1.6	2.1	5.8	1.1	1.8	1.4	1.2	1.3	2.4	1.7	-0.5	1.3	1.8	0.8	1.4	1.7	1.5	-1.1	1.0
Medication: Gliclazide	0.2	0.3	1.1	-0.1	0.2	0.1	0.0	1.1	0.0	0.5	0.8	0.5	0.8	0.8	0.6	0.0	0.0	-0.3	-0.3
Illnesses of father: None of the above (group 1)	0.2	0.2	0.6	-0.4	-0.3	-0.6	-0.7	-0.2	-0.7	-0.3	0.2	0.0	0.2	-0.1	-0.2	-0.8	-0.5	0.3	-0.7
Smoking status: Current	0.1	0.1	0.6	-0.5	-0.3	-0.4	-0.7	-0.3	0.2	0.3	-0.3	0.4	0.1	0.3	0.0	-0.4	-0.0	0.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	3.8	0.5	0.7	0.9	1.3	1.9	1.5	1.1	0.7	0.9	1.7	0.9	1.2	1.1	0.8	-0.8	0.4
Whole body water mass	0.4	2.3	4.2	-2.0	-1.6	-1.9	-0.7	-0.3	-1.8	-1.2	-0.7	-1.1	-1.4	-1.3	-0.9	-2.0	-1.9	1.7	-1.9
Leg predicted mass (right)	0.3	1.8	4.2	-2.0	-1.3	-1.9	-0.6	-0.1	-1.9	-0.8	-0.3	-0.6	-1.0	-0.9	-0.5	-1.9	-1.6	1.5	-2.0
Arm fat mass (left)	0.3	1.3	4.8	-1.9	-1.0	-2.0	-0.6	0.5	-0.6	-0.1	-0.3	0.0	-0.6	-0.7	-0.1	-1.5	-1.2	1.3	-2.2
Number of self-reported non-cancer illnesses	1.2	2.1	5.6	0.1	1.2	0.4	1.9	2.4	1.4	2.0	1.2	1.8	1.2	1.3	2.1	1.1	1.3	-0.8	-0.0
Average weekly champagne plus white wine intake	1.3	1.7	4.5	-1.7	-1.4	-1.7	-1.4	-0.8	-2.1	-1.1	-0.6	-1.0	-1.0	-1.0	-1.0	-1.3	-1.3	1.4	-1.5
Miserableness	0.7	1.2	4.5	-1.3	-1.1	-1.3	-1.4	-0.9	-2.1	-0.3	0.8	0.1	-0.9	-0.6	-0.6	-1.1	-1.0	1.1	-1.5
Guilty feelings	1.4	2.0	4.6	-1.0	-1.6	-1.2	-1.8	-2.1	-1.7	-1.6	-0.6	-1.4	-1.4	-1.2	-1.5	-1.4	-1.6	1.2	-0.9
Wears glasses or contact lenses	2.0	2.4	3.7	-1.5	-1.7	-1.5	-1.3	-1.5	-0.6	-1.6	-0.8	-1.8	-1.6	-1.9	-1.8	-1.6	-1.7	1.8	-1.2
Ever taken oral contraceptive pill	1.5	1.7	5.1	-0.0	1.1	0.1	2.0	2.3	-0.3	1.6	2.1	1.4	1.0	0.8	1.7	1.2	1.2	-0.4	-0.3
Hearing aid user	19.2	21.7	33.4	-5.3	-4.9	-5.8	-4.9	-4.0	-3.8	-4.3	-2.6	-3.6	-4.7	-4.4	-4.3	-5.2	-5.3	5.2	-5.1
Mother’s age at death	1.5	1.9	4.6	-0.7	-1.2	-0.6	-1.2	-1.5	1.1	-1.8	-0.7	-2.1	-0.8	-2.1	-2.0	-1.3	-1.6	1.4	-0.2
Financial situation satisfaction	0.5	0.6	2.9	0.6	0.1	0.8	1.1	1.2	1.1	0.3	1.7	-0.1	0.3	0.1	0.1	0.8	0.7	-0.4	0.8
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.9	-0.3	0.1	-0.4	-0.2	0.1	0.1	0.6	0.4	0.9	-0.5	0.6	0.4	-0.5	-0.1	-0.2	-0.3
Commuting to job workplace: Public transport	1.0	1.2	4.0	-0.9	0.4	-0.4	0.4	1.1	0.3	1.7	0.8	1.9	2.0	1.3	1.5	0.4	0.7	-0.2	-1.2
Eye problems/disorders: Glaucoma	0.3	0.4	1.8	-0.3	0.0	-0.3	-0.1	0.3	-1.1	0.8	-0.6	1.4	0.6	0.9	0.7	-0.0	0.3	-0.3	-0.5
Medication: Blood pressure	0.1	0.1	0.6	-0.1	0.2	0.1	0.5	0.4	0.8	0.3	-0.2	0.1	0.2	-0.3	0.5	0.4	0.2	0.2	-0.0
Pain type(s) experienced in last month: Hip pain	1.2	1.5	3.8	1.7	1.7	1.5	1.0	0.7	1.9	0.9	0.4	0.4	0.2	0.6	0.9	1.5	1.0	-1.3	1.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.9	0.9	-0.5	0.6	0.6	-0.4	1.0	-1.4	0.1	-2.0	-1.2	-0.7	-0.8	0.3	-0.4	-0.2	1.2
High cholesterol (Self-reported)	0.5	0.9	2.5	-1.4	0.2	-1.3	-0.5	0.7	-0.3	1.3	-0.5	1.5	0.6	0.5	1.3	-0.7	-0.1	0.5	-1.6
Medication: Bendroflumethiazide	0.1	0.2	0.5	0.3	0.4	0.2	0.1	0.2	0.7	0.7	-0.4	0.6	0.1	0.4	0.7	0.3	0.5	-0.4	0.3
Medication: Paracetamol	0.1	0.1	0.5	0.2	0.2	0.1	-0.5	-0.7	-0.1	-0.1	-0.6	-0.2	-0.7	-0.1	-0.3	0.1	-0.0	-0.0	0.2
Medication: Lisinopril	0.7	0.9	1.6	0.7	1.2	0.8	1.0	0.4	1.3	1.1	0.4	0.9	1.1	0.6	1.2	1.1	1.1	-0.9	0.5
Medication: Atorvastatin	4.5	5.6	11.7	1.9	2.8	2.3	2.2	1.8	1.7	2.6	2.1	2.3	3.4	2.7	2.6	2.5	2.3	-2.5	1.5
Illnesses of father: High blood pressure	0.2	0.3	1.1	0.6	0.2	0.8	-0.1	-0.8	-0.2	-0.3	0.2	-0.6	-0.7	-0.1	-0.4	0.4	0.1	-0.3	1.0
Alcohol drinker status: Never	0.2	0.2	1.2	-0.0	-0.2	-0.3	0.1	-0.1	0.0	-0.5	-1.1	-0.8	-0.8	-0.5	-0.5	-0.1	-0.7	0.3	0.1
Ever smoked	0.2	0.4	1.2	-0.9	-0.5	-1.0	-0.6	-0.4	-0.3	-0.2	0.4	-0.2	-0.1	-1.0	-0.4	-0.7	-0.5	1.1	-0.8
Basal metabolic rate	0.4	2.2	4.5	-2.1	-1.6	-2.0	-0.6	-0.1	-1.7	-1.1	-0.7	-0.9	-1.3	-1.1	-0.8	-2.0	-1.9	1.6	-2.1
Leg fat percentage (left)	0.2	0.7	2.2	-0.9	0.0	-1.1	0.4	1.5	1.1	1.0	-0.2	0.9	0.1	0.3	0.9	-0.5	-0.1	0.3	-1.4
Arm fat-free mass (left)	0.5	2.4	4.6	-2.1	-1.7	-2.1	-0.7	-0.1	-1.3	-1.2	-0.9	-1.2	-1.6	-1.5	-1.0	-2.0	-1.9	1.9	-2.0
Number of operations (self-reported)	0.4	0.7	2.0	0.1	0.4	0.2	1.2	1.4	1.4	0.8	-0.7	0.6	1.3	-0.5	0.6	0.9	0.7	0.2	0.3
Average weekly beer plus cider intake	2.1	3.1	5.7	2.2	1.7	2.1	1.6	1.4	1.4	1.4	1.2	1.3	1.9	2.2	1.5	1.4	1.8	-2.4	1.9
Irritability	0.9	1.5	2.8	-1.5	-1.3	-1.4	-1.7	-1.0	-0.7	-0.8	-0.8	-0.6	-0.8	-1.2	-0.9	-1.6	-1.4	1.5	-1.5
Risk taking	2.9	4.3	7.7	1.5	2.1	1.6	2.6	2.8	2.4	2.3	1.5	1.9	1.8	2.3	2.3	2.1	2.1	-2.0	1.3
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.0	0.7	0.1	0.8	0.2	-0.3	0.6	-0.5	-0.0	-0.6	-0.3	-0.4	-0.6	0.3	0.2	-0.2	1.0
Fractured/broken bones in last 5 years	0.2	0.2	1.8	-0.3	-0.4	-0.4	-0.3	0.0	-0.4	-0.3	1.3	-0.2	-0.5	-0.4	-0.4	-0.7	-0.3	0.4	-0.1
Age started oral contraceptive pill	3.7	4.7	6.4	-2.1	-2.3	-2.3	-2.5	-2.3	-1.4	-2.0	-2.2	-1.9	-2.1	-2.2	-2.3	-2.1	-2.2	2.4	-2.0
Diastolic blood pressure, automated reading	0.9	2.6	6.1	1.5	1.6	1.4	2.5	1.7	2.0	1.4	1.4	0.8	0.7	1.2	1.7	2.2	1.9	-1.5	1.6
Ever depressed for a whole week	0.4	0.4	1.0	-0.9	-0.5	-0.9	0.6	0.8	1.0	-0.2	0.7	-0.6	-0.4	-0.6	-0.1	0.2	-0.2	0.8	-1.0
Unable to work because of sickness or disability	0.3	0.4	2.0	0.3	0.5	0.7	0.7	0.4	1.4	0.5	-0.0	0.4	-0.1	0.6	0.6	0.7	0.7	-0.5	0.4
Commuting to job workplace: Cycle	5.9	7.1	10.8	-2.0	-3.0	-1.9	-2.6	-3.1	-3.3	-3.2	-2.7	-2.8	-2.7	-2.1	-3.2	-2.7	-2.8	2.2	-1.6
Myopia	0.4	0.6	2.2	0.2	0.8	0.8	0.9	1.0	0.1	1.1	0.2	0.9	1.5	0.8	1.0	0.6	0.7	-0.6	-0.0
Vascular/heart problems diagnosed by doctor	0.9	2.6	7.1	-0.6	-1.4	-0.8	-2.4	-2.7	-2.5	-1.9	-1.0	-1.5	-1.0	-0.8	-2.2	-1.4	-1.6	0.8	-0.5
Cholesterol lowering medication	0.3	0.4	1.0	-0.7	0.2	-0.5	-0.1	0.6	-0.0	0.9	-1.0	0.9	0.7	0.5	0.8	-0.3	-0.0	0.1	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.3	0.1	-0.1	0.1	0.3	0.3	-0.1	-0.0	0.1	-0.1	-0.5	0.1	0.1	-0.1	0.1	-0.1	0.3
Pain experienced in last month	0.4	0.6	1.7	-0.8	-0.3	-0.5	-1.2	-0.1	-1.3	0.5	-0.8	1.1	0.9	0.9	0.5	-0.8	-0.1	0.0	-1.1
Supplements: Calcium	1.9	2.1	3.8	1.8	1.8	1.8	1.4	1.3	1.2	1.2	0.2	1.3	1.2	1.7	1.4	1.2	1.4	-1.9	1.7
Basal cell carcinoma (self-reported)	0.1	0.1	0.3	-0.4	-0.0	-0.5	-0.2	0.3	-0.5	0.3	0.4	0.3	0.3	-0.2	0.2	0.2	0.0	0.3	-0.5
Heart attack/myocardial infarction (self-reported)	1.6	2.0	3.0	1.0	1.6	1.3	1.4	1.4	1.1	1.7	1.3	1.5	1.4	1.5	1.6	1.6	1.5	-1.4	0.8
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	5.7	2.1	1.8	1.8	1.5	0.9	2.4	1.0	0.6	0.7	0.8	0.8	1.1	1.8	1.6	-1.6	2.1
Heart disease (siblings)	0.4	0.5	1.9	-0.6	0.2	-0.3	0.7	1.4	0.3	0.8	1.2	0.8	0.5	0.5	1.0	-0.3	0.2	0.1	-0.7
Alcohol drinker status: Previous	1.1	1.2	4.9	0.9	1.3	0.8	0.9	1.4	2.2	1.1	0.6	1.1	0.6	0.9	1.2	1.1	1.1	-0.9	0.7
Pack years of smoking	0.7	1.1	3.3	0.1	0.7	0.1	0.7	1.2	0.9	1.4	1.5	1.5	0.6	1.8	1.2	0.5	0.7	-0.9	-0.6
Impedance of whole body	0.6	2.9	5.3	1.6	1.6	1.6	0.8	1.3	1.5	2.0	1.4	2.2	2.3	2.2	1.7	1.7	1.8	-1.9	1.2
Leg fat mass (left)	0.2	1.0	4.1	-1.6	-0.7	-1.7	-0.1	1.0	0.3	0.2	-0.4	0.2	-0.4	-0.4	0.2	-1.2	-0.9	1.0	-2.0
Arm predicted mass (left)	0.3	1.7	3.4	-1.8	-1.5	-1.8	-0.3	0.1	-1.1	-1.1	-0.6	-1.1	-1.4	-1.2	-0.8	-1.7	-1.6	1.5	-1.8