Hub : Genes

FAM171A1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0930	0.0260	1.8e-06	0.034	0.043	0.031	0.040	0.046	4.7e-05	5.5e-06	9.5e-05	9.7e-06	2.7e-06
2	GTEx	Muscle Skeletal	0.1975	0.0499	1.0e-06	0.038	NA	0.022	NA	0.025	1.1e-04	NA	3.0e-03	NA	1.6e-03
3	GTEx	Nerve Tibial	0.2845	0.0585	2.3e-08	0.096	NA	0.205	NA	0.229	2.7e-07	NA	1.6e-14	NA	3.2e-16
4	GTEx	Pituitary	0.2890	0.0970	7.9e-03	0.264	NA	0.167	NA	0.303	2.6e-07	NA	5.6e-05	NA	2.4e-08
5	GTEx	Stomach	0.1520	0.0560	2.6e-03	0.080	NA	0.078	NA	0.070	1.2e-04	NA	1.4e-04	NA	2.9e-04
6	NTR	Blood	0.0350	0.0136	3.3e-03	0.007	0.006	0.003	0.008	0.001	2.3e-03	3.4e-03	2.8e-02	8.6e-04	1.0e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.0958	0.0254	3.4e-07	0.046	0.055	0.130	0.090	0.111	1.1e-06	1.2e-07	2.2e-16	1.3e-11	4.2e-14
8	YFS	Blood	0.2541	0.0307	0.0e+00	0.093	0.169	0.193	0.196	0.181	1.2e-28	5.6e-53	5.3e-61	4.0e-62	4.9e-57
9	TCGA	Breast Invasive Carcinoma	0.0204	0.0103	4.1e-03	0.002	0.008	0.014	NA	0.005	1.1e-01	7.0e-03	5.2e-04	NA	2.8e-02
10	TCGA	Colon Adenocarcinoma	0.0680	0.0340	6.4e-03	0.004	0.022	0.007	NA	0.000	1.8e-01	1.9e-02	1.2e-01	NA	3.3e-01
11	TCGA	Prostate Adenocarcinoma	0.0341	0.0167	6.1e-03	0.013	0.015	0.016	NA	0.013	1.5e-02	8.5e-03	7.7e-03	NA	1.5e-02
12	TCGA	Thyroid Carcinoma	0.0400	0.0190	4.1e-03	0.052	0.030	0.033	NA	0.040	7.9e-06	5.5e-04	3.3e-04	NA	8.1e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	1.1	1.8	4.9	1.3	1.6	1.2	-1.7	0.2	-0.2	2.2	1.1	1.2	0.6	1.6	1.5
Bipolar Disorder or Schizophrenia	2.0	4.8	11.8	2.5	2.6	1.0	-0.9	0.7	1.0	2.8	1.8	3.0	1.9	3.4	2.5
Depressed Affect (Nagel 2018)	1.1	2.3	5.4	-1.6	-0.1	-1.7	-1.5	-0.8	2.2	-1.6	1.2	-0.9	0.4	-2.1	-2.3
Depression (Nagel 2018)	1.0	1.4	4.9	-0.6	0.7	-1.7	-2.2	-0.1	-0.8	-1.1	0.9	-0.6	0.3	-1.7	-1.5
Intelligence (Savage-Jansen 2018)	0.6	1.8	5.9	-1.4	-1.9	-0.2	-0.5	-2.4	-1.6	0.3	0.2	-1.2	-2.3	-0.6	0.2
Neuroticism (Nagel 2018)	0.7	1.7	4.7	-1.0	0.3	-1.4	-1.4	-0.5	1.4	-2.0	0.0	-0.4	1.1	-1.9	-2.2
Schizophrenia (2018)	1.7	3.6	9.7	2.1	2.1	0.3	0.2	0.6	1.4	1.9	1.4	2.9	2.0	3.1	2.0
Schizophrenia vs Biploar Disorder	0.3	0.4	2.3	0.5	-0.1	-1.1	1.0	-0.3	0.2	-0.1	0.3	0.5	0.3	1.5	-0.1
Worry (Nagel 2018)	0.4	0.8	1.9	-0.1	0.7	-0.8	-1.2	-0.5	1.2	-0.9	0.0	0.8	1.0	-0.8	-1.4
Alzheimer’s Disease (in mother)	1.0	1.2	4.0	0.8	1.3	1.5	-0.4	1.0	-1.5	1.0	-0.6	0.7	2.0	-0.7	0.4
Alzheimer’s Disease (in father)	1.5	1.6	3.2	0.6	1.0	0.9	-1.5	-0.1	1.4	1.8	1.7	1.4	-0.1	1.2	1.8
Alzheimer’s Disease (including proxy)	0.7	1.0	2.7	0.5	1.1	1.0	-1.3	-0.4	-0.5	1.7	0.5	1.0	1.2	-0.2	1.2
Crohns Disease (2017)	2.9	6.4	13.8	-3.3	-3.3	-0.9	-0.1	-1.8	-1.3	-3.7	0.8	-3.6	-3.7	-2.4	-1.5
Irritable Bowel Disease (IBD)	1.0	2.4	6.6	-1.4	-2.3	0.5	0.5	-0.6	-1.6	-2.6	-0.8	-2.2	-2.4	-0.3	0.2
Ulcerative Colitis (UC)	0.5	1.0	2.5	0.4	-0.8	1.5	1.1	0.2	-0.7	-0.8	-1.1	-0.2	-0.8	1.6	1.4
Major Depression (MDD)	0.6	0.8	6.6	-0.4	0.8	-0.0	-2.6	-0.0	0.7	0.6	0.3	0.4	0.7	-0.7	0.1
Reaction Time	4.7	8.9	20.2	4.5	4.1	3.1	0.2	3.7	0.5	3.2	-0.9	3.0	2.9	3.3	2.6
Verbal and Numeric Reasoning (VNR)	0.8	1.8	6.0	-1.1	-1.6	0.5	-2.0	-1.8	-1.5	0.5	-0.8	-0.8	-2.5	-0.4	0.5
Breast Cancer	0.5	1.2	5.1	-0.0	-1.1	-1.3	2.3	-0.8	0.3	0.9	1.8	0.4	-0.9	0.0	-0.1
Ovarian Cancer	0.8	1.0	3.3	-0.4	1.4	-0.8	-1.2	-0.3	0.6	0.0	-0.1	0.4	1.7	-1.0	-1.8
Prostate Cancer	1.5	2.1	5.2	-1.6	-1.8	-0.9	0.2	-2.2	-0.2	-0.5	0.6	-1.0	-1.6	-2.3	-1.9
Age at First Birth	1.1	1.7	3.4	1.7	0.7	1.7	1.0	1.4	1.0	0.7	-0.7	1.7	0.1	1.5	1.8
Bipolar Disorder (2011)	1.2	1.2	3.7	0.9	0.9	1.9	-1.5	0.3	0.1	0.7	1.2	1.4	0.2	1.0	1.2
Body Mass Index (BMI) (2010)	0.7	0.9	4.6	-1.3	-0.4	-0.7	-2.1	-0.9	-1.3	0.4	-0.5	-0.8	-0.8	-0.2	0.1
Coronary Artery Disease (CAD)	1.4	1.7	4.8	-2.2	-1.3	-1.0	0.6	-0.7	-0.6	-1.8	-0.4	-1.8	-1.2	-1.4	-1.5
Crohns Disease (2012)	3.6	5.8	15.2	-3.3	-2.6	-1.3	-0.8	-1.6	-2.6	-3.9	-0.3	-3.5	-2.7	-1.8	-1.7
Mean Putamen Volume	0.8	0.9	3.2	-0.5	-1.0	-1.2	0.4	-0.9	-0.4	-0.4	1.7	-0.9	-1.8	0.0	0.1
Fasting Glucose	0.4	0.5	1.4	0.6	0.1	-0.1	0.8	-0.0	-0.4	1.2	1.0	0.7	0.3	1.1	0.8
HbA1C	0.3	0.4	1.5	0.1	-0.8	0.4	0.7	-0.3	-0.1	-0.3	-0.3	-0.6	-1.2	0.3	1.1
HDL Cholesterol	1.0	1.7	4.9	1.1	-0.7	2.0	1.0	0.9	-0.6	-0.7	0.4	-0.1	-1.7	1.9	2.2
LDL Cholesterol	0.1	0.2	0.7	-0.9	-0.2	-0.4	-0.2	-0.2	0.6	-0.1	-0.3	-0.1	0.2	-0.5	-0.5
Lupus	0.4	0.5	2.0	-0.8	-0.8	-0.3	0.8	-1.0	-0.5	-0.6	-0.7	-1.4	0.2	-0.4	0.2
Neuroticism (2016)	1.0	1.4	3.8	-1.1	-0.7	-1.9	-0.9	-1.1	1.5	-1.0	1.7	-0.9	-0.8	-0.8	-1.1
Primary Biliary Cirrhosis	1.2	1.7	6.7	1.0	2.0	-0.5	-0.2	2.1	0.7	1.6	0.3	0.7	2.6	-0.8	-0.0
Rheumatoid Arthritis	0.6	0.9	2.7	0.7	1.0	-1.4	-0.8	1.0	0.2	1.4	1.6	0.4	0.5	-0.1	0.1
Schizophrenia (2014)	2.3	5.0	14.5	2.4	2.5	0.2	-0.4	0.3	1.9	2.7	1.9	3.8	2.2	3.3	1.7
Triglycerides	0.7	1.1	2.6	-1.3	-0.0	-1.1	-0.5	-1.2	-0.4	-0.7	-1.6	-1.6	0.6	-1.3	-1.2
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.2	-0.5	-0.6	0.7	0.7	-0.9	-0.9	-0.7	0.5	-0.9	-1.1	1.2	1.5
Ulcerative Colitis	0.3	0.5	2.5	0.6	-0.3	0.6	1.6	0.1	-0.1	-0.4	-0.8	-0.5	-0.1	0.9	0.9
Blood Eosinophil Count	0.0	0.3	1.0	0.3	0.4	0.9	-0.4	-0.4	1.0	0.0	-0.5	0.9	0.3	0.4	-0.1
Blood Platelet Count	0.1	0.8	2.1	0.7	0.6	0.4	1.2	1.0	0.6	0.7	-1.4	-0.5	1.4	-0.1	0.8
Blood Red Count	0.2	1.7	7.0	-1.2	-1.1	-1.2	0.7	-0.6	-1.9	-1.5	-0.6	-2.6	-0.9	-1.0	0.1
Blood White Count	0.2	1.7	6.5	-0.4	-0.1	0.4	0.4	0.8	-1.5	-1.6	-2.5	-2.5	0.3	-0.8	-0.6
Heel T-Score	0.1	1.0	3.8	0.2	0.2	-0.3	-0.5	0.1	-0.7	0.5	-1.9	-1.7	0.9	-1.3	-1.1
BMI	0.3	2.0	9.2	0.3	0.5	-0.1	-0.6	0.8	-2.4	-0.3	-3.0	-2.0	1.2	-1.2	-0.9
Height	0.1	1.9	10.6	-0.6	-0.9	-1.8	0.6	-1.3	1.6	-0.1	3.2	-0.6	-0.6	-0.6	-1.2
Waist Hip Ratio (WHR)	0.3	1.5	4.8	0.4	-0.1	0.5	1.1	1.1	-1.5	-0.9	-2.2	-1.6	-0.1	1.3	1.6
Systolic Blood Pressure	0.3	1.5	7.4	0.0	-1.0	0.1	2.7	1.0	-1.4	-1.6	-1.7	-1.0	0.2	0.3	-0.1
Smoking Status	0.7	1.7	2.4	-1.5	-1.5	-1.5	-0.6	-1.4	0.7	-1.1	1.5	-1.0	-1.4	-1.4	-1.4
Allergy or Eczema	0.4	1.0	4.2	0.6	0.7	0.9	-1.6	0.3	-2.0	1.2	-0.2	1.3	0.5	0.3	0.6
Cardiovascular Disease	0.6	2.0	9.7	-0.4	-0.3	0.3	1.0	1.1	-0.5	-0.6	-3.1	-1.7	1.9	-1.7	-1.5
Hypothyroidism (self reported)	0.7	1.6	3.9	-1.1	-1.4	-1.2	-0.2	-2.0	0.8	-1.8	0.5	-0.2	-1.7	-0.7	-1.7
Respiratory disease	0.6	1.3	5.0	1.2	1.5	-0.3	-1.0	0.3	-0.9	2.2	0.6	0.4	0.4	1.4	1.7
Type 2 Diabetes (T2D) (2018)	0.2	0.5	1.8	0.2	0.9	-0.9	-0.5	-0.3	-0.9	0.7	1.4	0.0	0.6	0.1	-0.3
Lung FEV1/FVC ratio	0.8	4.3	10.5	-1.8	-2.2	-2.2	1.6	-0.4	-3.1	-2.8	1.1	-3.2	-1.1	-1.8	-1.4
Lung FVC	1.1	5.6	11.0	-3.0	-2.7	-3.2	1.8	-2.6	0.6	-2.0	1.0	-2.5	-1.7	-3.3	-2.5
Neuroticism	1.1	2.7	8.0	-0.2	1.9	-1.3	-2.6	0.6	2.8	-0.6	1.2	0.4	2.2	-1.4	-1.9
Chronotype (morning person)	1.1	2.5	4.8	2.0	2.2	1.1	0.3	2.0	-0.5	2.1	1.1	1.4	1.8	1.8	1.2
Hair Pigment	0.0	0.7	2.9	0.9	-0.0	0.4	-0.3	0.2	-0.5	0.8	-0.3	-0.9	-1.5	0.8	1.7
Tanning	0.2	2.3	5.1	-2.1	-1.6	-1.3	-0.3	-1.2	-0.3	-2.2	0.1	-2.3	-0.1	-2.0	-1.7
Hand grip strength (left)	0.9	2.4	6.7	-2.6	-1.8	-1.0	-0.1	-1.8	0.4	-1.6	1.0	-2.2	-1.4	-1.6	-1.3
Number of treatments/medications taken	0.2	0.3	1.3	0.4	0.1	-0.8	-0.3	-0.1	0.5	1.0	-0.3	0.2	0.4	-0.4	-1.1
Average weekly spirits intake	1.4	1.7	4.3	-1.1	-0.6	-0.4	-0.1	-0.3	-1.5	-1.4	-1.9	-2.1	0.8	-2.1	-1.4
Sensitivity / hurt feelings	1.0	1.7	4.8	-0.8	0.1	-2.1	-0.8	-0.1	1.1	-0.7	2.2	-0.3	0.9	-1.9	-1.9
Frequency of depressed mood in last 2 weeks	1.2	1.7	6.2	-0.5	0.4	-1.8	-2.5	-0.8	-0.3	-0.1	2.2	-1.1	-0.6	-1.6	-0.8
Hearing difficulty/problems: Yes	0.2	0.3	1.3	-0.4	-0.5	-0.9	-0.2	-1.2	0.7	-0.3	0.3	-0.3	-0.5	-0.4	-0.3
Relative age of first facial hair	0.2	0.4	2.2	0.0	0.3	0.1	0.0	0.6	-1.5	-0.6	-0.6	-0.7	0.6	-0.5	-0.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.1	0.4	0.5	0.4	-0.2	1.0	0.9	0.3	-1.1	0.2	0.4	0.3	0.7
Ever used hormone-replacement therapy (HRT)	0.8	1.0	2.2	-0.7	-1.1	-1.3	0.3	-0.9	0.2	-0.7	0.2	-1.5	-0.4	-1.5	-1.4
Ever had hysterectomy (womb removed)	1.7	1.9	6.7	-1.9	-0.9	-2.6	-0.1	-1.7	0.6	-0.4	1.4	-0.5	-0.2	-1.5	-1.8
Systolic blood pressure, automated reading	0.4	1.2	5.9	0.7	-0.1	-0.3	2.4	1.1	-1.2	-0.5	-1.5	-1.2	1.0	0.5	0.5
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	4.3	1.0	0.7	0.3	-1.6	0.1	-0.8	1.9	0.3	1.5	0.7	1.7	2.1
Angina	0.4	0.6	1.8	-0.1	0.3	1.0	-1.1	-0.3	1.3	0.2	0.8	1.1	-0.6	0.6	0.5
Medication for hormone replacement therapy	0.3	0.3	1.4	-0.2	-0.4	-1.2	-0.5	-0.3	-0.3	-0.1	0.2	-0.8	-0.6	-0.4	-0.7
Vitamin and mineral supplements	1.9	2.6	8.7	-2.3	-1.7	-0.6	-1.8	-3.0	-0.1	-1.0	-1.8	-0.9	-1.0	-1.5	-1.5
Supplements: Zinc	2.1	2.2	4.9	2.0	1.6	0.8	0.9	1.6	0.2	1.4	0.6	1.9	0.9	2.2	2.1
Medication: Co-codamol	1.2	1.4	5.5	1.5	0.4	0.8	0.4	0.8	-1.1	1.6	0.3	0.9	-0.1	1.5	2.4
Medication: Metformin	0.2	0.3	1.5	-0.0	0.1	-0.5	-0.2	-0.6	-1.2	0.6	0.8	0.1	-0.1	0.1	-0.5
Diabetes (father)	1.2	1.5	3.8	-0.7	0.8	-0.4	-1.2	0.7	-0.1	-0.7	-1.8	-1.1	1.6	-1.9	-1.9
Diabetes (mother)	0.7	0.9	2.5	-1.5	-1.0	-0.7	1.3	-0.8	0.3	-1.6	0.2	-0.4	-0.9	0.3	-0.9
Severe depression (siblings)	0.7	0.8	5.5	0.4	1.2	-0.1	-0.2	0.6	2.3	0.1	0.2	0.3	1.4	-0.0	-0.3
Pack years adult smoking proportion	0.4	0.6	1.6	0.3	1.0	0.9	-1.2	0.5	-1.3	-0.6	0.4	0.5	0.5	1.0	0.6
Impedance of leg (right)	0.4	2.2	6.4	1.5	1.9	1.3	0.8	1.2	0.7	1.1	0.9	1.7	2.5	1.5	1.2
Leg fat-free mass (left)	0.5	2.5	6.4	-1.8	-1.4	-1.3	-1.1	-1.0	0.4	-1.5	-1.0	-2.4	-1.3	-2.5	-1.8
Trunk fat percentage	0.6	2.3	15.1	1.1	1.0	1.6	0.2	0.8	-1.7	0.0	-3.9	-0.1	1.9	0.1	-0.3
Hand grip strength (right)	1.2	3.2	8.7	-2.5	-1.5	-2.2	0.4	-0.7	0.3	-1.7	1.6	-3.0	-0.8	-2.4	-2.0
Townsend deprivation index at recruitment	3.4	4.7	10.7	3.3	2.9	2.4	-0.3	1.9	0.8	2.5	-0.6	2.7	1.8	2.2	2.4
Current tobacco smoking	0.3	0.5	2.1	0.4	-0.7	0.5	1.4	0.8	-0.4	-0.8	0.7	0.8	-0.5	0.3	0.3
Average weekly fortified wine intake	0.7	0.8	3.8	0.1	-0.4	1.0	0.0	0.1	-0.7	0.2	-0.4	-0.5	-0.7	1.7	2.0
Maternal smoking around birth	0.5	0.7	2.8	-0.3	-0.5	-1.6	0.6	-0.4	1.7	-1.2	0.6	-0.6	-0.2	0.1	-0.4
Fed-up feelings	0.9	1.6	4.6	1.0	2.0	-0.7	-1.0	1.3	1.8	0.8	1.4	-0.0	2.1	-0.8	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.5	-0.2	0.8	-1.7	-1.9	0.5	-1.3	0.0	1.4	-0.7	0.8	-1.4	-0.2
Relative age voice broke	0.3	0.4	1.8	0.1	0.4	0.9	0.5	0.4	-0.7	-0.3	-0.3	-0.0	0.2	1.2	1.3
Taking other prescription medications	0.1	0.2	0.8	0.2	0.5	0.0	-0.7	0.2	0.5	0.4	0.2	0.9	0.1	0.4	0.2
Age when periods started (menarche)	0.5	1.1	5.4	-0.8	-1.7	-0.4	2.3	-0.8	0.2	-0.5	-0.9	-0.4	-1.1	0.9	0.0
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	3.5	-1.1	-0.6	-1.5	-0.2	-0.6	-1.2	-0.9	-0.4	-0.7	0.3	-1.9	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	5.4	-0.7	-0.9	-1.4	0.2	-0.5	-1.0	-0.8	-1.7	-2.3	-0.3	-1.4	-1.1
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	5.5	1.8	2.4	0.8	-1.9	1.7	1.8	1.8	-0.1	1.4	2.1	0.4	0.8
Qualifications: CSEs or equivalent	1.6	2.1	7.1	-1.2	-0.8	-0.6	0.7	-0.1	1.1	-2.5	0.0	-2.1	0.3	-2.7	-1.9
Serious illness, injury or assault to yourself	1.3	1.5	5.0	1.5	1.9	0.4	-0.4	2.2	-0.1	1.5	-0.2	1.4	1.5	0.8	0.7
High blood pressure	0.1	0.4	2.5	-0.3	-0.4	0.4	1.1	0.1	-0.5	-0.2	-1.6	-0.2	0.4	-0.0	-0.4
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.6	-0.1	0.3	1.2	-1.6	0.4	-1.1	-0.2	-0.4	0.7	0.0	-0.8	-0.6
Multivitamins +/- minerals	1.9	2.4	7.3	2.7	1.3	1.6	1.4	2.5	0.0	0.7	1.0	0.5	0.4	1.6	2.1
Stomach or abdominal pain in last month	0.7	0.9	3.3	-0.7	-0.3	-0.4	-1.0	0.1	-0.0	-1.2	-1.8	-1.5	0.5	-1.1	-0.8
Supplements: Glucosamine	0.6	0.8	5.2	0.5	0.2	-0.5	0.4	1.4	0.8	0.7	2.3	-0.1	-0.2	-0.5	-0.0
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	4.0	-0.1	0.7	0.6	-0.2	0.7	2.0	-0.2	-0.2	-0.7	1.1	-1.1	-1.4
Medication: Atenolol	0.6	0.8	3.0	0.8	0.6	1.3	0.5	0.4	-0.7	0.7	-0.8	1.7	0.5	1.2	-0.0
Medication: Levothyroxine sodium	1.6	2.7	6.5	-2.5	-1.4	-1.0	-1.0	-2.2	0.2	-2.0	-0.9	-1.4	-1.0	-1.6	-2.5
Sitting height	0.4	3.2	9.2	-1.4	-0.4	-1.9	-2.3	-1.3	3.0	0.3	2.5	-0.6	-0.4	-2.4	-1.9
Chronic bronchitis/emphysema (father)	0.3	0.3	1.2	0.4	-0.1	0.4	0.5	0.1	0.8	0.0	-1.1	-0.1	0.6	-0.8	-0.5
High blood pressure (mother)	0.8	1.2	2.9	-1.2	-1.1	-1.7	-0.7	-1.5	-0.4	0.2	0.8	-1.0	-0.9	-1.3	-1.1
Body mass index (BMI)	0.4	1.5	7.6	-0.5	-0.6	0.1	-0.5	-0.6	-1.6	-1.1	-2.8	-1.9	-0.3	-1.2	-0.8
Impedance of leg (left)	0.5	2.5	8.7	1.7	2.3	1.3	0.3	1.3	0.5	1.2	0.7	1.8	2.9	1.7	1.3
Leg predicted mass (left)	0.5	2.4	6.3	-1.8	-1.4	-1.3	-1.1	-0.9	0.4	-1.4	-1.2	-2.5	-1.2	-2.5	-1.8
Trunk fat mass	0.4	1.6	12.1	0.3	0.4	0.8	-0.2	0.2	-1.4	-0.4	-3.5	-1.0	1.2	-0.8	-0.9
Waist circumference	0.4	1.3	9.5	0.4	0.2	0.7	-0.3	0.4	-1.8	-0.3	-3.1	-1.4	0.6	-0.4	0.1
Number of incorrect matches in round	1.1	1.9	6.2	1.7	2.2	0.9	0.3	1.5	0.3	1.3	-1.4	1.2	2.5	0.3	-0.2
Past tobacco smoking	0.4	0.7	2.8	1.0	0.3	1.7	0.5	0.6	-0.9	0.0	-0.6	0.6	0.3	0.9	1.3
Alcohol usually taken with meals	1.2	1.9	4.2	-1.7	-0.6	-1.0	-2.0	-1.3	-0.8	-1.2	-0.3	-1.8	-0.6	-1.7	-1.9
Nervous feelings	0.7	1.4	4.3	1.2	1.1	-0.4	-0.3	0.4	2.1	1.1	1.5	1.5	0.5	1.4	0.9
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.7	8.0	2.4	2.8	0.7	-1.9	1.3	-0.9	2.7	0.9	2.4	1.8	1.6	2.0
Hearing difficulty/problems with background noise	0.3	0.5	2.5	0.5	0.6	-1.3	0.0	0.0	1.6	0.9	-0.0	-0.3	0.7	-0.6	-0.1
Hair/balding pattern: Pattern 2	1.7	2.2	6.1	2.1	1.3	0.4	1.9	2.5	-0.4	0.7	-0.8	-0.8	0.9	1.8	2.1
Had menopause	0.5	0.7	1.8	-0.8	-1.0	-0.6	0.4	-0.6	-0.8	-1.3	-0.6	-1.3	-0.7	-0.3	-0.6
Had other major operations	3.2	3.9	12.5	-3.5	-2.3	-1.9	-0.9	-2.1	0.7	-1.6	0.8	-1.1	-2.0	-2.7	-2.1
Forced vital capacity (FVC)	1.3	5.2	12.0	-2.5	-1.9	-2.4	1.0	-1.3	3.0	-2.4	1.2	-3.5	-0.9	-3.2	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	6.5	-0.7	-1.1	-0.1	-0.7	-0.7	-0.9	-1.0	-2.5	-2.2	-1.0	-1.4	-0.7
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	8.6	0.0	0.3	-0.6	-2.9	-0.1	0.3	1.1	0.8	1.1	-0.3	0.1	0.3
Qualifications: None of the above	0.3	0.5	3.1	0.0	0.3	-1.8	-0.0	0.4	1.0	-0.7	-0.1	-1.1	0.4	0.3	-0.4
Financial difficulties in last 2 years	2.6	3.5	6.6	2.5	2.5	2.1	-0.9	1.7	0.2	1.7	-0.8	1.6	1.7	2.3	2.6
Mouth/teeth dental problems	1.0	1.5	5.3	-1.1	-1.1	0.0	1.0	0.5	-0.8	-1.9	-0.7	-2.3	0.0	-1.6	-1.1
Heart attack	0.8	1.0	4.6	-0.3	-0.5	-0.0	0.1	-0.3	1.6	-0.3	2.1	1.1	-1.4	0.7	-0.4
Allergy	0.3	0.7	3.6	0.5	0.2	-0.8	1.6	0.4	1.9	0.5	0.1	0.1	1.1	0.1	0.2
Pain all over the body in last month	0.3	0.3	1.4	-0.9	-0.4	-1.1	-0.2	0.0	0.4	-1.2	0.0	-0.2	-0.1	0.4	-0.2
Diabetes (self-reported)	0.5	0.8	2.6	-1.0	-0.4	-1.6	-0.6	-1.2	-0.8	0.3	0.8	-0.2	-0.6	-0.6	-1.4
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.3	-0.4	-0.4	-0.3	-0.4	0.3	-0.6	-0.4	0.6	-0.6	-0.2	-1.2	-1.0
Medication: Ramipril	1.2	1.6	5.0	-1.4	-1.3	-1.3	0.5	-1.6	1.0	-0.9	2.2	0.6	-1.4	-0.1	-1.2
Medication: Simvastatin	0.6	0.9	3.2	-1.1	-0.9	-0.2	0.5	-1.5	-0.1	-0.6	-0.3	-0.1	-0.4	-1.4	-1.8
Fluid intelligence score	0.6	1.2	5.4	-0.7	-1.4	1.6	-0.4	-1.4	-0.8	-0.2	-1.0	0.1	-2.3	0.1	0.5
Illnesses of siblings	0.3	0.4	2.9	-0.3	-0.0	0.9	-1.7	0.1	0.8	-0.6	-0.2	0.0	-0.4	0.1	0.2
Neuroticism score	1.5	3.1	9.4	0.4	2.1	-1.7	-2.4	0.7	3.1	0.2	2.1	0.4	2.3	-1.2	-1.4
Weight	0.3	1.7	5.4	-0.9	-0.6	-0.4	-0.8	-0.8	-0.7	-1.0	-2.3	-2.2	-0.2	-1.9	-1.5
Impedance of arm (right)	1.0	4.6	10.2	2.5	2.0	3.2	1.0	2.0	0.2	2.0	-0.6	3.0	2.3	2.5	2.1
Arm fat percentage (right)	0.3	1.3	10.3	0.6	-0.2	1.5	0.4	0.2	-1.3	-0.3	-3.2	-0.9	0.2	-0.2	0.1
Trunk fat-free mass	0.6	3.6	9.0	-2.3	-1.4	-1.8	-1.4	-1.6	1.2	-1.4	0.2	-2.9	-1.6	-3.0	-2.1
Hip circumference	0.1	0.5	2.9	-0.1	0.0	0.6	-0.6	-0.5	-0.3	0.2	-1.7	-0.9	0.2	-1.3	-0.3
Time employed in main current job	0.5	0.5	1.5	-0.2	0.8	-1.0	-0.7	-0.4	0.2	1.0	-0.3	0.7	0.8	0.0	-1.2
Alcohol intake versus 10 years previously	0.2	0.3	1.6	-0.5	-0.3	-0.6	0.5	-0.1	-1.3	-0.5	0.4	-0.7	-0.0	-0.3	-0.6
Father’s age at death	0.8	1.0	2.8	-1.2	-0.5	-0.2	-1.6	-1.3	-0.6	-0.9	-0.3	-1.3	-0.7	-1.7	-0.5
Worrier / anxious feelings	0.6	1.1	3.1	-0.5	-0.3	-1.0	-0.0	-0.1	1.0	-1.8	0.9	-1.3	0.4	-1.6	-1.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.0	0.9	1.7	-1.4	-1.3	0.4	-0.0	1.1	1.2	-0.1	1.3	0.3	1.1
Falls in the last year	0.4	0.6	1.8	-0.8	-0.6	-1.4	-0.8	-0.4	-0.3	-0.8	-0.2	-1.2	-0.8	-0.6	-0.8
Hair/balding pattern: Pattern 3	0.3	0.5	2.9	0.1	0.1	0.2	-0.1	-0.5	-0.4	1.0	0.7	1.7	0.6	-0.6	-0.3
Number of live births	2.2	3.2	4.8	-2.1	-1.9	-2.2	2.1	-2.2	1.5	-1.2	2.0	-0.9	-1.4	-1.6	-1.7
Forced expiratory volume in 1-second (FEV1)	2.3	7.8	19.5	-2.9	-2.0	-3.3	1.2	-1.0	2.8	-2.8	2.2	-4.3	-0.8	-4.4	-2.8
Pulse rate	1.6	2.6	4.7	2.1	1.3	0.5	1.4	2.2	-1.2	1.9	-1.4	0.3	1.9	1.9	2.1
Happiness	0.6	0.8	2.5	0.7	0.6	-0.0	-0.4	0.2	1.3	1.6	1.0	1.4	0.6	0.6	0.5
Noisy workplace	0.2	0.2	0.5	0.4	-0.4	0.1	0.6	0.3	-0.7	-0.1	-0.5	-0.7	-0.4	0.3	0.3
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.5	-0.7	-1.1	0.9	-0.1	-1.2	1.2	0.4	0.3	0.4	-1.6	-0.0	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.0	-1.4	-1.1	-0.8	0.5	-1.4	-1.0	-0.6	-0.5	-0.8	-1.1	-0.2	-0.0
Mouth/teeth dental problems: Dentures	0.6	1.0	3.6	-1.0	-0.9	-1.9	-0.1	-0.7	0.6	-0.5	0.6	-0.4	-1.1	-1.0	-1.8
Asthma	0.4	0.7	1.5	0.4	0.8	0.7	-1.1	-0.1	-1.0	1.2	0.5	0.6	-0.3	1.2	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.3	0.8	1.0	-1.0	0.1	1.0	0.5	0.9	-0.0	-0.9	1.5	-1.5	-0.5
Medication: Cholesterol lowering	0.7	1.0	5.2	-1.0	-1.2	-0.1	-0.4	-2.3	0.5	-0.3	0.1	0.6	-1.4	-0.4	-1.2
Depression (self-reported)	1.2	1.4	4.3	0.2	0.7	-1.9	-0.4	0.2	1.3	1.0	2.1	-0.8	0.8	-1.4	-1.6
Medication: Lansoprazole	2.4	2.7	8.8	2.0	2.5	0.7	0.4	1.2	-1.3	2.2	-0.7	2.0	3.0	0.8	0.0
Prospective memory result	0.5	0.6	1.9	-0.0	0.6	-1.1	-1.2	-0.1	1.4	0.1	1.2	-0.0	0.3	-0.2	-0.6
Lung cancer (father)	0.2	0.2	0.9	-0.5	0.3	-0.2	0.3	0.0	-0.7	-0.4	-0.2	-0.6	0.6	-0.5	-0.9
Illnesses of mother	0.2	0.3	2.0	0.2	-0.1	0.3	0.4	0.6	1.4	-0.7	0.1	-0.1	0.3	-0.1	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.8	17.4	-2.4	-1.5	-2.7	0.8	-0.7	2.0	-2.5	1.6	-3.9	-0.4	-4.2	-2.8
Pulse wave Arterial Stiffness index	0.4	0.5	1.6	-0.2	0.8	-0.5	-0.5	0.8	-1.3	-0.3	-0.4	-0.6	0.9	-0.5	-0.9
Impedance of arm (left)	0.9	4.0	8.4	2.6	1.8	2.6	1.2	1.9	0.2	2.0	-0.7	2.9	2.2	2.3	1.7
Arm fat mass (right)	0.3	1.2	7.0	-0.3	-0.5	0.4	-0.1	-0.4	-0.7	-0.9	-2.7	-1.8	-0.1	-1.3	-0.8
Trunk predicted mass	0.7	3.7	9.1	-2.4	-1.5	-1.8	-1.5	-1.7	1.4	-1.5	0.2	-2.9	-1.6	-3.0	-2.1
Standing height	0.1	1.1	4.2	-0.7	0.4	-1.0	-0.7	-0.1	2.1	0.2	0.7	-0.7	0.8	-1.6	-1.6
Length of working week for main job	0.4	0.4	1.3	-0.7	-0.0	0.2	-1.0	0.2	0.4	-0.3	-1.0	-0.9	0.2	-1.1	-0.4
Exposure to tobacco smoke at home	0.4	0.4	1.6	-0.0	0.8	-0.4	-1.2	0.8	0.4	-0.2	0.5	-1.0	0.3	-0.9	0.0
Breastfed as a baby	1.5	1.8	6.3	-1.0	-0.2	-2.4	0.9	-0.8	-0.8	0.2	-0.2	-1.3	1.1	-1.9	-2.5
Tense / ‘highly strung’	0.9	1.5	3.4	1.2	1.7	-0.7	-0.9	0.2	1.1	1.1	1.3	1.9	1.8	0.9	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.2	-1.1	-0.5	-1.5	-1.4	-1.1	0.7	-0.6	1.5	0.1	-1.2	-0.9	-1.5
Hair/balding pattern: Pattern 4	0.8	1.8	3.9	-1.7	-1.1	-0.7	-1.5	-1.6	-0.1	-1.5	0.4	-0.8	-1.5	-1.8	-2.0
Birth weight of first child	0.4	0.7	1.8	-0.7	-1.2	0.1	-0.7	-0.5	1.3	-1.1	-0.1	-0.8	-1.0	-0.6	-0.0
Peak expiratory flow (PEF)	2.7	6.3	14.8	-1.2	-0.6	-3.6	2.2	1.0	3.4	-0.8	3.8	-3.2	0.1	-3.7	-2.3
Pulse wave reflection index	0.8	1.0	2.5	-0.8	-0.7	-0.2	0.3	-0.2	-1.6	-1.4	-0.2	-1.6	-0.8	-1.2	-1.3
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.8	-0.2	0.1	-0.6	-0.9	0.8	0.7	0.2	0.8	-0.4	-0.0	-0.6	-0.3
Loud music exposure frequency	0.6	0.7	2.9	0.8	0.1	0.3	-0.5	-0.8	-0.0	1.2	0.0	0.8	-0.2	1.1	1.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.7	-0.4	0.2	-0.8	-0.7	-0.1	-0.7	1.1	1.4	0.9	0.2	-1.7	-1.2
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.3	0.2	1.2	0.7	-1.5	-0.3	0.5	1.5	-0.5	1.4	0.9	0.7	1.4
Blood clot in the leg (DVT)	0.4	0.5	1.5	0.6	-0.2	-1.2	1.0	-1.0	-1.0	0.7	-0.0	-0.5	-0.5	-0.0	-0.4
Medication: Paracetamol	0.4	0.6	2.0	0.7	1.0	-0.9	-0.4	0.4	1.4	0.3	0.7	0.1	1.3	-0.5	-0.5
Headache pain in last month	0.5	0.9	2.7	0.4	0.9	-1.5	-1.6	0.6	0.5	-0.0	0.8	-1.2	0.4	-0.8	-0.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.1	0.4	1.1	0.1	-1.4	1.3	-0.8	0.6	0.7	-0.1	0.8	-0.1	0.8
Glaucoma (self-reported)	0.7	0.8	2.1	0.4	-0.7	0.1	0.7	-0.6	-1.1	0.1	0.9	1.1	-1.4	1.3	1.2
Gout (self-reported)	0.4	0.6	2.0	-0.8	-0.1	0.5	-0.6	-0.2	-0.5	-1.2	-0.9	-1.0	-0.2	-1.4	-0.6
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	3.9	-1.5	-1.3	-1.0	-0.7	-2.0	0.1	-1.8	-0.5	-0.8	-1.3	-0.9	-2.0
Medication: Amlodipine	0.3	0.5	1.7	-1.0	-0.4	-0.1	-0.2	-0.5	0.6	-1.3	-0.4	-0.7	-0.3	-0.7	-1.0
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.7	-0.2	0.0	-0.6	-0.6	0.4	0.2	0.2	-0.4	-0.8	-0.4	-0.2	0.5
Birth weight	0.2	0.3	1.0	-0.5	-0.1	-0.6	-0.9	-0.3	0.1	-0.7	0.7	0.1	0.1	-1.0	-0.7
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.4	0.7	0.7	0.4	-0.4	0.2	-1.6	0.0	-0.8	1.4	0.7	1.4	-0.1
High blood pressure (siblings)	0.5	0.7	3.9	-0.1	0.1	-2.0	0.6	-0.5	-0.3	0.9	1.0	-0.4	0.6	-0.9	-0.3
Forced vital capacity (FVC), Best measure	1.1	4.2	10.5	-2.3	-1.3	-2.4	0.5	-1.2	2.3	-1.9	1.1	-3.0	-0.4	-3.2	-2.5
Body fat percentage	0.5	1.8	13.0	0.8	0.5	1.3	0.4	0.5	-2.0	-0.2	-3.6	-0.7	1.4	-0.1	-0.2
Leg fat percentage (right)	0.3	1.1	7.0	0.5	0.4	0.8	0.3	0.1	-1.8	-0.1	-2.6	-0.8	1.0	-0.2	-0.1
Arm fat-free mass (right)	0.8	3.9	9.8	-2.3	-1.3	-2.6	-1.3	-1.4	0.4	-1.9	-0.2	-3.1	-0.9	-3.1	-2.4
Exposure to tobacco smoke outside home	1.2	1.6	6.9	1.7	1.3	1.6	0.5	1.2	-0.6	0.7	-0.1	0.3	0.9	1.5	2.6
Comparative body size at age 10	0.5	1.4	8.3	1.0	1.6	0.5	-2.9	0.2	0.6	1.6	0.6	-0.1	0.7	-0.1	0.5
Number of full brothers	0.3	0.4	1.8	0.5	0.5	-0.8	-0.2	0.6	-1.4	0.8	0.2	0.2	0.8	-0.1	0.0
Worry too long after embarrassment	1.3	2.2	6.8	-1.1	0.4	-2.6	-2.0	-0.4	1.5	-0.7	0.1	-1.1	1.3	-2.2	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.8	-0.5	-0.2	-0.8	-0.3	0.2	-1.7	-0.1	1.1	-0.4	-0.8	0.2	-0.0
Wheeze or whistling in the chest in last year	0.5	0.8	3.1	0.1	0.9	-1.6	-1.2	0.1	-1.8	0.8	-0.5	-0.0	0.9	-0.6	-0.2
Number of children fathered	1.3	1.4	4.3	-0.8	0.2	-2.1	1.4	-0.4	0.3	0.4	1.3	-0.7	1.2	-1.6	-1.9
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	2.3	-0.8	-0.7	-1.1	-0.8	-1.5	0.7	0.7	1.5	-0.7	-0.5	-1.0	0.4
Age at first live birth	0.7	1.2	5.2	0.3	0.1	1.4	-0.1	0.1	-2.3	0.5	-1.5	1.0	0.2	1.5	0.9
Pulse wave peak to peak time	0.5	0.6	2.5	0.2	-0.8	0.7	0.4	-0.9	1.6	0.2	0.4	0.7	-1.1	0.5	0.9
Health satisfaction	2.0	2.7	4.6	2.2	1.7	1.9	-1.2	1.4	0.2	1.9	-1.3	1.9	1.3	1.8	1.9
Shortness of breath walking on level ground	0.8	1.0	2.2	1.0	1.3	0.2	-1.5	0.8	1.1	0.9	0.5	0.6	0.3	1.3	1.3
Qualifications: College or University degree	0.4	1.3	3.1	0.3	-0.4	1.8	-1.3	-1.1	-0.9	1.3	-0.6	1.4	-1.4	0.8	1.3
Eye problems/disorders: None of the above	0.6	0.7	2.1	-1.0	-0.5	0.7	-1.0	-1.4	0.5	-1.2	-0.1	-0.1	-1.2	0.2	0.0
Mouth/teeth dental problems: Loose teeth	1.3	1.5	5.7	0.7	0.8	0.0	-0.6	-0.2	0.5	1.9	2.4	1.7	-0.3	1.4	1.3
Emphysema/chronic bronchitis	1.5	1.6	3.1	-1.4	-0.8	-1.5	-0.8	-0.8	-1.6	-1.0	-1.8	-1.8	-0.5	-1.3	-1.3
Medication for pain relief, constipation, heartburn	0.4	0.6	3.0	0.6	0.7	1.7	-0.1	0.8	-0.7	0.0	-0.5	0.7	-0.1	0.8	1.2
Neck or shoulder pain in last month	0.4	0.6	4.8	0.0	0.3	-0.4	-2.2	-0.6	0.3	0.6	0.3	-0.5	-0.2	-0.2	0.6
Medication: Blood pressure	0.4	0.7	2.4	-0.5	-0.9	0.3	1.5	-1.0	0.7	-1.3	-0.8	-0.5	-0.4	0.4	-0.5
Angina (self-reported)	0.4	0.6	1.6	-0.3	0.2	1.0	-1.2	-0.5	1.0	0.1	0.9	0.9	-0.8	0.5	0.5
Migraine (self-reported)	0.8	1.0	3.2	-1.1	-0.8	-0.8	-1.8	-1.0	-0.7	-0.7	0.5	-1.5	-1.2	-0.3	0.6
Medication: Ibuprofen	1.1	1.3	3.8	1.0	1.4	-1.7	-0.3	1.1	0.1	1.1	-0.1	-0.6	2.0	-1.5	-1.0
Medication: Allopurinol	0.7	0.9	2.8	0.5	0.7	1.6	-1.2	0.4	-1.4	0.4	-1.7	0.9	0.6	0.1	0.4
Medication: Omeprazole	0.3	0.4	1.0	-1.0	-0.9	-0.6	0.9	-0.2	-0.0	-0.6	0.7	-0.4	-0.4	-0.6	-0.6
Medication: Seretide 50 evohaler	0.5	0.6	2.0	-0.4	0.1	0.9	-1.1	-0.3	-0.7	-0.7	-1.4	-1.1	-0.0	0.4	0.4
Mean time to correctly identify matches	7.3	14.0	27.9	5.3	5.1	3.4	-0.2	4.3	-1.1	4.2	-1.4	4.1	3.7	4.6	3.4
Heart disease (mother)	0.5	0.6	1.8	-0.6	-0.4	-1.0	-0.3	-0.2	1.0	-0.4	0.9	-1.3	-0.0	-1.2	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.5	-0.6	-0.8	-1.2	0.2	-1.6	1.0	-0.4	1.2	0.6	-1.2	0.8	-0.2
Whole body fat mass	0.3	1.4	9.4	-0.1	-0.0	0.5	-0.2	-0.1	-1.4	-0.6	-3.1	-1.6	0.7	-1.1	-0.9
Leg fat mass (right)	0.3	1.3	5.8	-0.6	-0.4	-0.1	-0.5	-0.5	-1.1	-0.9	-2.4	-1.9	0.2	-1.5	-1.2
Arm predicted mass (right)	0.8	4.1	10.6	-2.4	-1.3	-2.7	-1.3	-1.4	0.6	-1.8	-0.3	-3.1	-0.9	-3.3	-2.5
Pulse rate, automated reading	0.9	2.9	6.9	2.6	1.4	0.2	2.2	2.6	-0.9	1.8	-1.0	0.3	1.8	1.4	1.8
Alcohol intake frequency.	0.3	0.7	2.1	-0.3	-0.0	-1.4	-0.1	-0.2	-1.3	-0.8	-0.4	-1.2	0.6	-0.7	-1.4
Comparative height size at age 10	0.1	0.8	3.4	0.2	0.7	-0.9	-0.7	-1.0	0.8	1.9	-0.1	0.4	0.8	-1.0	-0.7
Number of full sisters	2.2	2.6	9.5	1.4	1.7	-1.1	-0.4	1.2	3.1	1.8	2.6	1.4	1.2	0.8	0.9
Suffer from ‘nerves’	0.8	1.2	6.6	0.2	1.3	-1.3	-2.6	-0.9	0.3	0.5	1.1	0.3	1.4	-0.2	-0.2
Overall health rating	1.2	2.5	4.4	2.1	2.1	1.6	-1.8	1.4	-0.2	1.2	-1.4	1.3	1.3	1.9	1.7
Chest pain or discomfort	0.7	1.0	3.9	1.2	1.4	-0.7	-0.8	0.5	-0.1	2.0	0.2	0.9	0.4	1.0	1.4
Had major operations	1.9	2.3	4.6	-2.1	-1.1	-0.1	-1.5	-1.7	-1.7	-1.6	-1.3	-0.8	-1.0	-1.6	-2.1
Age at last live birth	0.6	0.9	3.1	0.5	0.2	0.4	-0.9	-0.9	-0.4	1.2	0.2	1.8	-0.4	1.4	1.1
Family relationship satisfaction	0.8	1.0	2.7	1.3	0.7	0.5	-0.3	0.3	0.9	1.6	0.6	1.6	-0.1	1.3	1.2
Leg pain on walking	0.7	0.8	4.3	0.3	0.7	0.6	-2.1	-0.3	-0.8	-0.6	-1.2	0.2	0.9	-0.9	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.6	0.1	0.0	-1.6	1.6	-0.1	-0.6	-0.2	-0.2	-0.9	0.6	-1.4	-1.1
Commuting to job workplace: Car/motor vehicle	0.6	0.7	3.0	0.1	0.5	-0.2	1.0	0.8	-0.5	-0.0	-0.1	0.7	1.0	-1.3	-1.7
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	4.2	-0.5	-0.7	-1.5	1.3	-0.2	1.4	-0.3	2.1	-0.5	-0.5	-0.6	-0.6
Medication: Aspirin	0.6	0.8	3.5	-0.8	-1.6	-0.3	0.1	-1.3	-0.2	-0.3	0.8	0.1	-1.9	0.6	-0.2
Supplements: Vitamin C	0.6	0.8	2.7	1.1	0.9	0.5	0.9	1.3	1.7	0.2	0.7	0.4	0.8	0.4	-0.1
Knee pain experienced in last month	0.5	0.8	1.9	1.0	1.3	1.3	-0.6	0.6	-0.1	0.8	-0.6	1.4	1.2	0.2	0.6
Hypertension (Self-reported)	0.1	0.4	3.1	-0.1	-0.3	0.3	1.0	0.2	-0.3	0.2	-1.8	-0.0	0.7	0.1	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.3	-0.2	0.1	-0.6	1.5	0.3	0.3	0.2	1.3	0.9	0.2	0.3	-0.3
Illnesses of father: Heart disease	1.1	1.5	6.7	-1.1	-2.0	-0.1	0.8	-2.6	0.5	-1.1	0.6	-0.2	-1.9	0.3	0.3
Illnesses of siblings: Diabetes	0.7	0.8	4.4	-0.5	-0.5	1.8	0.6	0.3	0.2	-0.1	-2.1	-0.7	0.1	-0.1	0.8
Smoking status: Previous	1.2	1.8	5.8	-1.5	-0.3	-2.4	-1.4	-1.2	1.0	-0.1	0.4	-1.3	-0.2	-1.8	-2.1
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.8	3.9	-1.2	-0.5	-1.9	-1.5	-0.8	2.0	-0.4	1.0	-1.7	-0.1	-2.0	-1.1
Whole body fat-free mass	0.6	3.2	8.4	-2.1	-1.4	-1.6	-1.5	-1.3	0.9	-1.5	-0.3	-2.8	-1.4	-2.9	-2.0
Leg fat-free mass (right)	0.5	2.5	5.8	-1.8	-1.4	-1.3	-1.4	-1.0	0.3	-1.5	-1.1	-2.4	-1.3	-2.4	-1.8
Arm fat percentage (left)	0.3	1.4	10.7	0.5	-0.4	1.1	0.6	0.1	-1.5	-0.4	-3.3	-1.1	0.2	-0.4	-0.2
Average weekly red wine intake	0.3	0.4	1.6	-0.1	-0.4	0.1	-0.6	-0.4	0.7	-0.0	-0.8	-1.3	0.0	-0.9	-0.6
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.8	-1.1	-0.7	0.1	-1.7	-1.6	-0.8	-1.0	-1.2	-1.6	-1.4	-0.7	-0.9
Mood swings	1.2	2.1	9.4	-0.7	0.4	-1.9	-1.5	0.1	1.7	-0.8	3.1	-1.2	0.5	-1.5	-1.2
Loneliness, isolation	0.4	0.6	1.6	-0.7	0.0	-1.2	-0.8	-1.1	0.3	-1.1	0.2	-0.2	-0.2	-0.2	-1.3
Long-standing illness, disability or infirmity	0.3	0.5	2.3	0.6	0.3	1.1	-0.4	0.2	-0.3	0.3	-1.5	0.5	-0.2	0.9	0.8
Ever had bowel cancer screening	0.4	0.5	2.2	-0.4	0.1	-1.5	-0.3	-0.1	-0.4	1.1	1.3	0.5	0.2	-0.1	-0.2
Diabetes diagnosed by doctor	0.7	1.1	4.2	-1.0	-0.3	-2.1	-0.9	-1.5	-0.6	0.3	1.5	-0.4	-0.6	-0.6	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	2.8	3.0	8.3	2.1	2.1	1.5	-0.6	1.0	0.9	2.9	0.5	1.8	2.1	1.6	2.0
Friendships satisfaction	0.2	0.3	1.8	-0.0	0.1	0.4	0.5	0.3	1.3	0.3	0.3	0.8	0.0	0.1	0.5
Qualifications: nursing, teaching	1.0	1.6	3.6	-1.8	-1.9	-0.8	0.1	-1.6	-0.9	-1.5	-0.3	-0.6	-1.5	-1.2	-1.4
Commuting to job workplace: Walk	1.1	1.2	3.8	-0.9	-1.7	0.5	-0.7	-1.9	-0.1	-0.5	-1.1	-1.1	-2.0	-0.4	-0.2
Eye problems/disorders: Cataract	0.6	0.7	2.2	-0.4	-0.2	-0.3	1.0	1.1	-0.8	-0.7	-0.1	-1.5	0.5	-1.2	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	4.0	1.4	0.4	0.1	0.3	0.6	0.0	2.0	0.6	0.8	-0.6	1.1	1.7
Medication for cholesterol	0.7	1.1	4.6	0.7	1.0	0.3	-0.5	0.1	1.4	0.5	1.0	0.3	0.1	1.7	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.9	-1.4	-0.9	-1.7	-0.6	-1.3	1.6	0.2	0.7	-0.1	-0.5	-1.6	-1.2
Back pain experienced in last month	0.8	1.2	3.5	0.1	0.5	-1.8	-0.7	0.6	1.3	0.0	1.9	-0.8	1.0	-1.3	-1.0
Mineral and other dietary supplements	0.9	1.2	3.3	-1.8	-1.2	-0.4	-1.2	-1.8	-0.5	-0.8	-1.1	-1.3	-0.6	-0.9	-0.4
Breast cancer (self-reported)	0.7	0.8	3.3	-0.8	-0.7	0.2	-0.3	0.1	-1.8	-1.5	-0.8	-1.2	-0.3	-0.2	-0.6
Asthma (self-reported)	0.6	1.2	3.2	0.8	1.3	1.1	-1.1	0.5	-1.0	1.5	0.2	0.8	0.1	1.6	1.8
Osteoporosis (self-reported)	0.4	0.5	1.8	0.4	0.7	0.5	-0.8	0.7	0.4	0.3	-0.3	1.3	0.4	1.1	0.4
Osteoarthritis (self-reported)	1.7	2.3	3.8	1.7	1.5	1.8	-0.6	1.6	-1.9	1.3	-2.0	1.4	0.9	1.3	1.3
Medication: Aspirin	0.4	0.5	1.8	-0.3	-0.9	0.0	-0.1	-1.1	-0.2	0.3	0.4	0.9	-1.3	1.2	-0.0
Medication: Gliclazide	0.3	0.4	1.1	0.5	0.4	-0.8	-0.1	0.3	-1.1	1.1	0.3	-0.1	0.8	-0.2	0.4
Illnesses of father: None of the above (group 1)	0.3	0.4	1.6	0.6	0.4	-0.1	1.1	1.3	-0.9	0.0	0.5	-0.1	0.1	-0.1	-0.5
Smoking status: Current	0.3	0.5	1.9	0.4	-0.8	0.7	1.4	0.7	-0.3	-0.9	1.0	0.8	-0.5	0.3	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.6	9.2	-2.4	-2.4	-2.3	1.5	-1.6	-0.0	-2.8	0.4	-2.8	-1.0	-3.0	-2.7
Whole body water mass	0.6	3.4	8.6	-2.2	-1.5	-1.8	-1.3	-1.4	0.9	-1.6	-0.3	-2.8	-1.5	-2.9	-2.1
Leg predicted mass (right)	0.4	2.4	5.7	-1.8	-1.2	-1.2	-1.4	-0.9	0.4	-1.5	-1.1	-2.3	-1.2	-2.4	-1.8
Arm fat mass (left)	0.3	1.3	7.7	-0.3	-0.5	0.3	-0.3	-0.4	-0.8	-0.8	-2.8	-1.9	-0.0	-1.3	-0.8
Number of self-reported non-cancer illnesses	0.7	1.2	2.3	1.4	0.7	1.1	0.3	1.0	-0.9	1.5	-1.5	1.2	0.7	1.0	0.9
Average weekly champagne plus white wine intake	0.9	1.2	3.7	-1.6	-1.3	-0.6	-0.7	-1.0	0.6	-1.3	-0.9	-1.9	-0.4	-1.2	-0.6
Miserableness	2.1	3.6	8.5	-1.3	-0.1	-2.6	-2.1	-1.4	2.8	-0.8	2.9	-0.8	-0.2	-2.3	-2.3
Guilty feelings	0.5	0.8	6.0	-0.0	-0.0	-1.5	-0.4	-0.2	0.6	-0.3	2.4	-0.2	-0.2	-0.7	-0.4
Wears glasses or contact lenses	0.8	0.9	3.9	-1.0	-0.8	-0.5	-0.3	-0.5	-0.5	-0.4	-0.3	-0.9	-1.2	-2.0	-1.5
Ever taken oral contraceptive pill	0.4	0.5	2.3	0.0	0.3	1.5	-0.7	0.1	-1.1	-0.4	-0.9	0.2	-0.7	0.3	-0.0
Hearing aid user	0.6	0.6	2.2	-0.5	1.2	-0.7	-1.5	0.5	0.4	0.0	-0.0	-0.6	1.3	-0.5	-0.6
Mother’s age at death	0.6	0.7	2.1	0.7	0.2	0.5	0.4	-0.1	-1.4	1.4	0.6	1.3	-0.3	1.0	1.0
Financial situation satisfaction	1.6	2.0	4.8	1.2	1.7	1.6	-2.2	1.2	1.6	1.7	-1.1	1.6	1.3	0.2	0.3
Tinnitus: Yes, now most or all of the time	1.1	1.3	4.0	-1.2	-1.6	-1.1	0.6	-1.2	-2.0	-0.8	0.2	-1.3	-1.1	-1.1	-0.6
Commuting to job workplace: Public transport	2.3	2.8	6.6	1.9	1.2	1.4	-1.5	0.4	0.6	2.2	-1.0	2.4	0.1	2.2	2.6
Eye problems/disorders: Glaucoma	0.6	0.8	2.8	0.9	0.2	-0.5	1.3	0.3	-0.1	1.0	0.5	1.7	0.3	1.1	0.8
Medication: Blood pressure	0.3	0.5	1.6	-0.6	-0.9	0.0	0.5	-0.1	-0.7	-0.2	-1.2	0.4	-0.5	-0.7	-1.1
Pain type(s) experienced in last month: Hip pain	1.2	1.5	6.1	0.5	1.5	1.3	-2.5	-0.3	-0.5	1.2	-0.5	1.1	1.5	1.0	1.2
Supplements: Fish oil (including cod liver oil)	0.6	0.8	4.3	0.6	-0.4	-0.8	2.1	0.4	0.2	-0.3	1.6	0.5	-0.4	-0.4	-1.0
High cholesterol (Self-reported)	0.3	0.6	1.8	-0.5	-1.0	0.3	1.3	-0.2	0.1	-0.1	-1.4	-0.2	0.1	-1.1	-1.0
Medication: Bendroflumethiazide	0.4	0.6	1.6	-0.5	-1.0	-1.0	-0.3	-0.5	-1.1	0.0	-0.1	0.0	-0.4	-1.3	-1.2
Medication: Paracetamol	0.6	1.0	4.1	1.1	1.2	-0.9	-0.4	0.5	2.0	0.8	0.4	0.5	1.4	-0.5	-0.8
Medication: Lisinopril	0.8	1.0	3.3	-1.0	-0.9	-0.5	0.9	-0.3	-0.8	-1.4	-0.6	-0.9	0.5	-1.5	-1.8
Medication: Atorvastatin	0.1	0.2	0.6	0.0	-0.8	-0.3	0.3	-0.8	-0.5	0.3	-0.4	0.2	-0.4	0.3	-0.1
Illnesses of father: High blood pressure	0.4	0.5	3.6	-0.4	0.3	-0.3	-1.9	-0.4	-0.0	0.4	0.7	0.3	0.2	0.3	1.0
Alcohol drinker status: Never	0.9	1.1	4.7	0.8	1.4	-1.1	0.4	1.2	0.5	0.8	0.3	1.0	2.2	-0.4	-0.9
Ever smoked	0.2	0.3	1.3	0.0	0.7	-0.7	-0.2	0.2	1.2	0.6	0.5	0.3	0.6	0.0	-0.7
Basal metabolic rate	0.5	2.8	7.5	-2.0	-1.3	-1.4	-1.3	-1.3	0.7	-1.5	-0.8	-2.7	-1.2	-2.7	-2.0
Leg fat percentage (left)	0.4	1.4	8.6	0.5	0.5	0.7	-0.0	0.0	-2.0	-0.3	-2.9	-1.0	1.2	-0.3	-0.3
Arm fat-free mass (left)	0.7	3.7	9.0	-2.3	-1.3	-2.2	-1.5	-1.5	1.1	-1.7	-0.3	-2.9	-1.0	-3.0	-2.3
Number of operations (self-reported)	4.2	6.2	15.0	-3.9	-3.0	-1.3	-1.1	-2.7	-0.8	-3.1	0.0	-2.3	-2.6	-3.1	-2.9
Average weekly beer plus cider intake	0.5	0.8	4.5	0.3	-0.8	-0.6	2.1	-0.2	-0.1	0.3	0.9	-0.9	-0.5	0.2	1.1
Irritability	0.5	0.8	2.4	1.1	1.3	-0.5	-1.2	1.4	0.8	0.5	0.3	0.2	1.5	0.0	-0.1
Risk taking	0.2	0.2	0.6	-0.4	-0.5	0.5	0.2	-0.4	0.3	-0.5	-0.8	-0.7	-0.6	0.2	-0.0
Ever had prostate specific antigen (PSA) test	0.7	0.8	3.6	-0.2	0.2	-1.6	-0.6	-1.1	0.9	0.7	-0.2	0.2	-0.0	-1.0	-1.9
Fractured/broken bones in last 5 years	0.4	0.5	3.0	0.4	0.6	0.3	0.4	1.2	1.7	0.6	-0.2	-0.2	0.3	-0.7	0.5
Age started oral contraceptive pill	1.0	1.3	6.2	0.2	-0.3	0.6	2.3	0.3	-2.5	-0.4	-1.1	1.0	0.0	0.9	-0.2
Diastolic blood pressure, automated reading	0.8	2.3	10.4	0.9	0.0	-1.0	2.5	0.9	-1.8	0.0	-3.2	-1.6	1.6	0.5	0.7
Ever depressed for a whole week	0.9	1.1	4.9	0.7	0.8	0.8	-2.2	0.2	0.0	1.4	0.4	1.4	-0.1	1.2	1.1
Unable to work because of sickness or disability	0.9	1.1	4.0	0.7	1.0	0.7	-1.3	1.2	1.4	0.0	-0.6	0.2	-0.1	1.4	2.0
Commuting to job workplace: Cycle	1.0	1.2	4.5	-0.9	-0.5	-1.7	0.2	-0.8	2.1	0.1	1.5	-1.1	-0.9	-0.7	-0.8
Myopia	0.4	0.6	2.2	0.5	0.1	0.8	-1.1	0.3	0.1	0.7	0.9	1.5	-0.4	0.6	0.6
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.1	-0.1	0.2	-0.9	-0.8	-0.4	-0.0	-0.2	1.1	-0.7	-0.4	-0.6	-0.0
Cholesterol lowering medication	0.6	0.9	3.4	-0.8	-0.5	-0.0	0.6	-0.4	-0.6	-0.7	-1.2	-0.3	0.5	-1.9	-1.8
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.1	-0.9	-0.9	-0.1	1.0	-0.5	-0.3	-0.8	0.1	-0.1	-0.6	-0.1	-0.3
Pain experienced in last month	0.2	0.4	1.9	-1.0	-0.6	0.0	1.4	-1.0	-0.1	0.4	-0.0	0.3	-0.2	-0.0	-0.3
Supplements: Calcium	2.6	2.9	6.1	2.1	2.0	1.6	0.7	2.4	-1.8	1.0	-0.1	2.5	1.9	1.8	0.9
Basal cell carcinoma (self-reported)	0.7	0.8	2.3	-0.9	-0.8	0.1	0.4	-0.7	1.2	-1.0	-1.4	-1.5	-0.5	-0.3	-0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.8	3.6	-0.1	-0.2	0.2	-0.0	0.0	1.8	-0.2	1.9	1.1	-1.1	0.6	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.4	0.6	-0.1	-1.2	1.0	-1.0	-0.8	0.8	0.2	-0.3	-0.7	0.1	-0.5
Heart disease (siblings)	0.9	1.1	4.8	0.7	-0.8	-0.5	2.2	-0.6	-1.9	0.6	-0.5	0.0	-1.0	1.1	0.1
Alcohol drinker status: Previous	0.6	0.7	1.7	-0.9	-0.7	-0.8	-0.3	-0.8	0.5	-1.1	-0.5	-0.3	-0.8	-1.0	-1.3
Pack years of smoking	0.3	0.5	2.4	-0.0	0.9	0.5	-1.0	0.4	-1.6	-0.8	0.3	0.3	0.4	0.8	0.1
Impedance of whole body	0.9	4.4	10.5	2.6	2.5	2.4	0.9	2.1	0.4	1.9	-0.2	2.6	3.2	2.2	1.8
Leg fat mass (left)	0.4	1.4	6.2	-0.5	-0.2	-0.2	-0.7	-0.5	-1.2	-0.8	-2.5	-1.9	0.4	-1.5	-1.2
Arm predicted mass (left)	0.7	3.6	8.7	-2.4	-1.3	-2.1	-1.3	-1.6	0.9	-1.7	-0.4	-2.8	-1.1	-2.9	-2.3