Hub : Traits :

Mean time to correctly identify matches

285 significantly associated models · 82 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 43757762 45187285 1 1 3.2e-09 9.0e-07 2.1e-02 78 SLC6A9
2 1 48301764 51180660 1 1 3.3e-07 6.3e-09 5.6e-03 77 AGBL4
3 1 96492298 97978299 1 1 2.2e-07 3.3e-06 1.5e-02 72 PTBP2
4 1 182744205 184266571 1 1 3.6e-07 3.6e-07 5.4e-03 70 SMG7
5 1 204982713 206329620 5 1 2.7e-10 6.7e-10 1.0e+00 100 NUCKS1
6 2 23729232 25278723 2 1 5.7e-08 2.6e-08 1.0e+00 100 AC009228.1
7 2 174238261 175806715 1 1 3.7e-07 8.6e-08 8.2e-02 89 OLA1
8 2 200473658 202044716 1 1 7.3e-09 9.4e-10 1.4e-02 84 SPATS2L
9 3 46365783 48077701 2 1 2.2e-07 8.1e-08 2.6e-02 83 SETD2
10 5 111499732 112950045 5 1 1.2e-10 2.0e-10 8.9e-02 93 REEP5
11 5 138933151 140423473 2 1 3.4e-09 2.0e-11 1.1e-03 76 HBEGF
12 6 108183628 109704062 1 1 4.2e-09 4.4e-11 2.6e-03 79 FOXO3
13 7 44090853 45498400 1 1 1.1e-07 1.4e-08 1.2e-02 80 ZMIZ2
14 7 109603832 111895681 1 1 4.0e-07 1.1e-07 1.0e+00 100 IMMP2L
15 7 122978928 124733550 1 1 3.8e-08 3.7e-09 2.4e-04 61 RP5-921G16.1
16 9 85855600 87315117 2 1 6.2e-11 6.7e-11 3.6e-02 90 RMI1
17 10 12239118 13839729 1 1 4.0e-08 1.1e-04 1.2e-01 84 CCDC3
18 10 14555086 16102103 1 1 1.3e-07 2.1e-07 1.0e-01 90 FAM171A1
19 11 30764890 32226445 1 1 1.4e-07 4.3e-06 7.7e-06 5 IMMP1L
20 11 44691479 48285906 15 3 4.6e-13 2.7e-11 4.2e-01 99 ARHGAP1 PEX16 RP11-430H10.1
21 11 63295034 64687797 1 1 1.8e-07 5.4e-07 1.0e+00 100 TRPT1
22 12 48605088 50364707 8 1 5.2e-12 4.2e-13 4.3e-03 84 CCDC65
23 12 111154626 113517494 12 1 3.2e-12 2.1e-11 6.5e-02 92 SH2B3
24 17 6456609 7856438 1 1 2.4e-07 1.6e-07 2.3e-06 19 C17orf81
25 17 43871147 45510971 8 2 3.0e-24 1.2e-19 7.8e-01 100 ARL17A KANSL1
26 17 75309351 76804316 2 1 1.3e-08 1.5e-07 8.4e-01 100 AC021593.1
27 18 33665455 35103667 1 1 7.6e-08 3.9e-10 7.0e-04 71 TPGS2
28 19 3309021 4735663 1 1 8.0e-08 1.8e-10 1.6e-04 65 PIAS4
29 20 46840115 48410403 2 1 4.7e-08 3.8e-07 2.0e-01 94 ARFGEF2

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Reaction Time 17.40 32 23 69.7 -1.00 1.2e-32 AC009228.1 AC021593.1 AGBL4 ARFGEF2 ARHGAP1 ARL17A C17orf81 CCDC3 CCDC65 FAM171A1 FOXO3 HBEGF IMMP1L IMMP2L KANSL1 NUCKS1 OLA1 PEX16 PIAS4 PTBP2 REEP5 RMI1 RP11-430H10.1 RP5-921G16.1 SETD2 SH2B3 SLC6A9 SMG7 SPATS2L TPGS2 TRPT1 ZMIZ2
Verbal and Numeric Reasoning (VNR) 3.35 5 3 9.1 -0.30 6.2e-01 ARFGEF2 ARHGAP1 CCDC65 FOXO3 HBEGF
Breast Cancer 0.91 2 0 0.0 0.00 1.0e+00 C17orf81 SLC6A9
Prostate Cancer 1.51 1 0 0.0 0.00 1.0e+00 NUCKS1
Bipolar Disorder 2.16 1 0 0.0 0.00 1.0e+00 CCDC65
Coronary Artery Disease (CAD) 1.53 1 0 0.0 0.00 1.0e+00 SH2B3
LDL Cholesterol 1.36 1 0 0.0 0.00 1.0e+00 SH2B3
Lupus 1.26 1 0 0.0 0.00 1.0e+00 SMG7
Primary Biliary Cirrhosis 1.49 1 1 3.0 0.00 1.0e+00 SH2B3
Rheumatoid Arthritis 1.35 1 0 0.0 0.00 1.0e+00 SH2B3
Schizophrenia 2.50 3 1 3.0 0.00 1.0e+00 ARHGAP1 IMMP2L PTBP2
Blood Eosinophil Count 5.96 2 2 6.1 0.00 1.0e+00 RMI1 SH2B3
Blood Platelet Count 1.59 6 5 15.2 -0.01 9.9e-01 ARL17A C17orf81 KANSL1 RMI1 SH2B3 TRPT1
Blood Red Count 2.22 8 4 12.1 -0.13 7.5e-01 AC009228.1 ARFGEF2 ARL17A IMMP1L PIAS4 SH2B3 SLC6A9 SPATS2L
Blood White Count 3.91 6 4 12.1 -0.40 4.3e-01 AC009228.1 AGBL4 PIAS4 RMI1 SETD2 SH2B3
Heel T-Score 1.66 7 5 15.2 -0.58 1.7e-01 ARHGAP1 C17orf81 CCDC65 IMMP1L PIAS4 REEP5 SETD2
BMI 2.46 10 6 18.2 0.14 6.9e-01 AGBL4 ARFGEF2 FOXO3 HBEGF NUCKS1 OLA1 PIAS4 PTBP2 REEP5 TRPT1
Height 1.66 16 12 36.4 0.30 2.5e-01 AC009228.1 ARFGEF2 ARL17A CCDC3 FOXO3 IMMP1L KANSL1 NUCKS1 OLA1 PEX16 PIAS4 REEP5 RMI1 RP5-921G16.1 SH2B3 ZMIZ2
Waist Hip Ratio (WHR) 1.21 3 2 6.1 0.00 1.0e+00 ARL17A KANSL1 SETD2
Systolic Blood Pressure 2.93 7 3 9.1 -0.54 2.1e-01 ARFGEF2 ARL17A C17orf81 FOXO3 OLA1 SH2B3 SPATS2L
Smoking Status 2.38 3 1 3.0 0.00 1.0e+00 AGBL4 IMMP2L KANSL1
Allergy or Eczema 1.03 1 0 0.0 0.00 1.0e+00 SH2B3
Cardiovascular Disease 2.34 2 1 3.0 0.00 1.0e+00 OLA1 SH2B3
Hypothyroidism (self reported) 4.42 1 1 3.0 0.00 1.0e+00 SH2B3
Type 2 Diabetes (T2D) 1.37 1 0 0.0 0.00 1.0e+00 SH2B3
Lung FEV1/FVC ratio 1.42 3 2 6.1 0.00 1.0e+00 ARFGEF2 FOXO3 NUCKS1
Lung FVC 1.78 8 4 12.1 0.39 3.4e-01 ARFGEF2 ARL17A C17orf81 FOXO3 KANSL1 RMI1 SH2B3 SPATS2L
Neuroticism 1.55 2 0 0.0 0.00 1.0e+00 ARHGAP1 KANSL1
Chronotype (morning person) 1.87 2 1 3.0 0.00 1.0e+00 HBEGF RMI1
Hair Pigment 0.22 5 3 9.1 -0.19 7.6e-01 ARL17A CCDC65 FOXO3 NUCKS1 SH2B3
Tanning 0.20 1 0 0.0 0.00 1.0e+00 SH2B3
Hand grip strength (left) 2.43 2 1 3.0 0.00 1.0e+00 KANSL1 NUCKS1
Number of treatments/medications taken 2.04 1 1 3.0 0.00 1.0e+00 SH2B3
Frequency of depressed mood in last 2 weeks 1.88 2 1 3.0 0.00 1.0e+00 ARFGEF2 ARHGAP1
Relative age of first facial hair 1.61 1 0 0.0 0.00 1.0e+00 FOXO3
Systolic blood pressure, automated reading 2.04 3 1 3.0 0.00 1.0e+00 ARL17A C17orf81 SH2B3
Vitamin and mineral supplements 1.70 1 0 0.0 0.00 1.0e+00 SETD2
Pack years adult smoking proportion 1.45 1 0 0.0 0.00 1.0e+00 AGBL4
Impedance of leg (right) 1.50 5 1 3.0 0.30 6.2e-01 CCDC65 FOXO3 HBEGF NUCKS1 SPATS2L
Leg fat-free mass (left) 2.18 8 5 15.2 -0.72 4.5e-02 AGBL4 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Trunk fat percentage 2.11 8 3 9.1 -0.65 7.8e-02 AGBL4 ARL17A FOXO3 KANSL1 PIAS4 PTBP2 RMI1 TRPT1
Hand grip strength (right) 2.22 2 1 3.0 0.00 1.0e+00 ARFGEF2 NUCKS1
Townsend deprivation index at recruitment 1.40 1 0 0.0 0.00 1.0e+00 AGBL4
Current tobacco smoking 1.79 1 0 0.0 0.00 1.0e+00 AGBL4
Fed-up feelings 1.93 2 1 3.0 0.00 1.0e+00 ARHGAP1 SH2B3
Relative age voice broke 1.42 1 0 0.0 0.00 1.0e+00 FOXO3
Taking other prescription medications 2.00 2 1 3.0 0.00 1.0e+00 HBEGF SH2B3
Age when periods started (menarche) 1.69 2 1 3.0 0.00 1.0e+00 CCDC65 FOXO3
Heel bone mineral density (BMD) T-score, automated (left) 1.30 1 1 3.0 0.00 1.0e+00 ARHGAP1
High blood pressure 2.32 3 1 3.0 0.00 1.0e+00 OLA1 PIAS4 SH2B3
Multivitamins +/- minerals 2.04 1 0 0.0 0.00 1.0e+00 NUCKS1
Medication: Atenolol 1.65 1 1 3.0 0.00 1.0e+00 SH2B3
Medication: Levothyroxine sodium 3.91 1 1 3.0 0.00 1.0e+00 SH2B3
Sitting height 1.77 7 5 15.2 -0.08 8.6e-01 AC009228.1 ARFGEF2 CCDC3 FOXO3 NUCKS1 PEX16 REEP5
Body mass index (BMI) 2.06 6 4 12.1 -0.24 6.4e-01 AGBL4 FOXO3 HBEGF PIAS4 PTBP2 TRPT1
Impedance of leg (left) 1.44 4 0 0.0 -0.47 5.3e-01 CCDC65 HBEGF NUCKS1 SPATS2L
Leg predicted mass (left) 2.20 8 6 18.2 -0.72 4.5e-02 AGBL4 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Trunk fat mass 2.34 10 3 9.1 -0.48 1.6e-01 AGBL4 ARL17A FOXO3 KANSL1 PIAS4 PTBP2 REEP5 RMI1 TRPT1 ZMIZ2
Waist circumference 2.08 5 2 6.1 -0.31 6.1e-01 AGBL4 FOXO3 KANSL1 PIAS4 REEP5
Past tobacco smoking 2.24 1 0 0.0 0.00 1.0e+00 SH2B3
Nervous feelings 2.01 1 0 0.0 0.00 1.0e+00 AGBL4
Hearing difficulty/problems with background noise 1.98 2 0 0.0 0.00 1.0e+00 ARHGAP1 NUCKS1
Forced vital capacity (FVC) 2.14 5 3 9.1 -0.71 1.8e-01 ARFGEF2 ARL17A KANSL1 PIAS4 SPATS2L
Heel bone mineral density (BMD) T-score, automated (right) 1.37 1 1 3.0 0.00 1.0e+00 ARHGAP1
Qualifications: None of the above 2.65 4 1 3.0 0.58 4.2e-01 ARFGEF2 FOXO3 SLC6A9 SPATS2L
Heart attack 1.68 1 0 0.0 0.00 1.0e+00 SH2B3
Medication: Simvastatin 1.21 1 0 0.0 0.00 1.0e+00 PIAS4
Fluid intelligence score 2.34 4 1 3.0 0.17 8.3e-01 ARFGEF2 ARHGAP1 FOXO3 HBEGF
Illnesses of siblings 1.99 1 0 0.0 0.00 1.0e+00 SH2B3
Neuroticism score 1.20 1 0 0.0 0.00 1.0e+00 ARHGAP1
Weight 2.36 9 5 15.2 -0.70 3.4e-02 AGBL4 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 TRPT1 ZMIZ2
Impedance of arm (right) 2.53 10 4 12.1 0.22 5.4e-01 ARL17A CCDC65 FOXO3 HBEGF IMMP1L IMMP2L NUCKS1 REEP5 RMI1 SH2B3
Arm fat percentage (right) 2.10 8 3 9.1 -0.78 2.2e-02 AGBL4 ARFGEF2 ARL17A FOXO3 KANSL1 PIAS4 PTBP2 TRPT1
Trunk fat-free mass 2.11 8 4 12.1 -0.42 2.9e-01 AGBL4 ARFGEF2 FOXO3 KANSL1 NUCKS1 REEP5 SH2B3 ZMIZ2
Hip circumference 1.92 7 3 9.1 -0.63 1.3e-01 AGBL4 FOXO3 PIAS4 PTBP2 SH2B3 TRPT1 ZMIZ2
Time employed in main current job 1.70 1 0 0.0 0.00 1.0e+00 OLA1
Father's age at death 1.96 1 1 3.0 0.00 1.0e+00 SH2B3
Frequency of tiredness / lethargy in last 2 weeks 2.11 2 0 0.0 0.00 1.0e+00 ARFGEF2 ARHGAP1
Number of live births 1.29 2 0 0.0 0.00 1.0e+00 AC021593.1 TRPT1
Forced expiratory volume in 1-second (FEV1) 2.00 4 3 9.1 -0.76 2.4e-01 ARFGEF2 ARL17A KANSL1 PIAS4
Happiness 1.53 1 0 0.0 0.00 1.0e+00 ARFGEF2
Qualifications: A levels/AS levels or equivalent 2.03 3 0 0.0 0.00 1.0e+00 ARFGEF2 SLC6A9 SPATS2L
Forced expiratory volume in 1-second (FEV1), Best measure 1.62 4 3 9.1 -0.72 2.8e-01 ARFGEF2 ARL17A KANSL1 PIAS4
Impedance of arm (left) 2.39 10 3 9.1 0.36 3.0e-01 AGBL4 ARL17A FOXO3 HBEGF IMMP1L IMMP2L REEP5 RMI1 SH2B3 SPATS2L
Arm fat mass (right) 2.34 9 4 12.1 -0.55 1.2e-01 AGBL4 ARL17A FOXO3 KANSL1 PIAS4 PTBP2 REEP5 TRPT1 ZMIZ2
Trunk predicted mass 2.14 8 4 12.1 -0.43 2.9e-01 AGBL4 ARFGEF2 FOXO3 KANSL1 NUCKS1 REEP5 SH2B3 ZMIZ2
Standing height 1.68 13 9 27.3 -0.39 1.8e-01 AC009228.1 ARFGEF2 ARL17A CCDC3 FOXO3 KANSL1 NUCKS1 PEX16 PIAS4 REEP5 RMI1 SH2B3 ZMIZ2
Tense / 'highly strung' 1.42 1 0 0.0 0.00 1.0e+00 NUCKS1
Birth weight of first child 2.91 3 1 3.0 0.00 1.0e+00 ARFGEF2 HBEGF SH2B3
Peak expiratory flow (PEF) 2.75 3 1 3.0 0.00 1.0e+00 FOXO3 NUCKS1 PEX16
Pulse wave reflection index 1.64 1 0 0.0 0.00 1.0e+00 RMI1
Qualifications: O levels/GCSEs or equivalent 2.38 4 0 0.0 -0.45 5.5e-01 ARFGEF2 PIAS4 RMI1 SLC6A9
Medication for cholesterol, blood pressure or diabetes 1.37 1 1 3.0 0.00 1.0e+00 SH2B3
Gout (self-reported) 1.27 1 0 0.0 0.00 1.0e+00 SH2B3
Hypothyroidism/myxoedema (self-reported) 3.81 1 1 3.0 0.00 1.0e+00 SH2B3
Birth weight 2.92 2 2 6.1 0.00 1.0e+00 C17orf81 SH2B3
High blood pressure (siblings) 1.50 1 0 0.0 0.00 1.0e+00 SH2B3
Forced vital capacity (FVC), Best measure 1.97 4 3 9.1 -0.69 3.1e-01 ARFGEF2 ARL17A KANSL1 PIAS4
Body fat percentage 2.10 8 2 6.1 -0.74 3.5e-02 AGBL4 ARFGEF2 ARL17A FOXO3 KANSL1 PIAS4 PTBP2 TRPT1
Leg fat percentage (right) 1.96 6 2 6.1 -0.62 1.9e-01 AGBL4 ARFGEF2 FOXO3 PIAS4 PTBP2 TRPT1
Arm fat-free mass (right) 2.26 7 5 15.2 -0.71 7.4e-02 AGBL4 FOXO3 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Comparative body size at age 10 2.18 4 2 6.1 -0.54 4.6e-01 ARL17A CCDC65 KANSL1 NUCKS1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.56 1 0 0.0 0.00 1.0e+00 NUCKS1
Qualifications: College or University degree 2.03 5 2 6.1 -0.29 6.3e-01 ARFGEF2 FOXO3 HBEGF SLC6A9 SPATS2L
Medication: Blood pressure 1.87 2 1 3.0 0.00 1.0e+00 PIAS4 SH2B3
Medication: Allopurinol 1.22 1 0 0.0 0.00 1.0e+00 SH2B3
Whole body fat mass 2.32 9 4 12.1 -0.54 1.3e-01 AGBL4 ARL17A FOXO3 KANSL1 PIAS4 PTBP2 REEP5 TRPT1 ZMIZ2
Leg fat mass (right) 2.33 7 4 12.1 -0.32 4.9e-01 AGBL4 FOXO3 KANSL1 PIAS4 PTBP2 REEP5 TRPT1
Arm predicted mass (right) 2.28 8 5 15.2 -0.47 2.4e-01 AGBL4 ARFGEF2 FOXO3 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Pulse rate, automated reading 1.98 4 1 3.0 -0.53 4.7e-01 CCDC65 PIAS4 SPATS2L TRPT1
Alcohol intake frequency. 0.96 1 0 0.0 0.00 1.0e+00 AC009228.1
Comparative height size at age 10 1.82 10 5 15.2 -0.40 2.5e-01 ARFGEF2 ARL17A CCDC3 FOXO3 KANSL1 NUCKS1 PIAS4 REEP5 RMI1 SH2B3
Suffer from 'nerves' 2.36 1 0 0.0 0.00 1.0e+00 ARHGAP1
Overall health rating 1.08 1 0 0.0 0.00 1.0e+00 SPATS2L
Chest pain or discomfort 1.64 2 0 0.0 0.00 1.0e+00 C17orf81 REEP5
Family relationship satisfaction 1.41 1 0 0.0 0.00 1.0e+00 ARFGEF2
Medication: Aspirin 1.50 1 0 0.0 0.00 1.0e+00 SH2B3
Supplements: Vitamin C 1.45 1 0 0.0 0.00 1.0e+00 RMI1
Knee pain experienced in last month 1.26 1 0 0.0 0.00 1.0e+00 SMG7
Hypertension (Self-reported) 2.24 3 1 3.0 0.00 1.0e+00 OLA1 PIAS4 SH2B3
Illnesses of father: Heart disease 1.77 1 0 0.0 0.00 1.0e+00 SH2B3
Smoking status: Previous 2.16 1 0 0.0 0.00 1.0e+00 SH2B3
Whole body fat-free mass 2.22 9 5 15.2 -0.47 2.0e-01 AGBL4 ARFGEF2 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Leg fat-free mass (right) 2.15 8 3 9.1 -0.73 3.9e-02 AGBL4 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Arm fat percentage (left) 1.95 8 3 9.1 -0.75 3.1e-02 AGBL4 ARFGEF2 ARL17A FOXO3 KANSL1 PIAS4 PTBP2 TRPT1
Handedness (chirality/laterality): Left-handed 1.59 2 0 0.0 0.00 1.0e+00 ARL17A KANSL1
Loneliness, isolation 2.46 3 1 3.0 0.00 1.0e+00 ARFGEF2 ARHGAP1 SH2B3
Mouth/teeth dental problems: Mouth ulcers 1.20 1 0 0.0 0.00 1.0e+00 SH2B3
Medication for cholesterol 1.38 1 1 3.0 0.00 1.0e+00 SH2B3
Illnesses of father: None of the above (group 1) 2.27 2 0 0.0 0.00 1.0e+00 PIAS4 SH2B3
Smoking status: Current 1.83 1 0 0.0 0.00 1.0e+00 AGBL4
Whole body water mass 2.20 9 5 15.2 -0.47 2.0e-01 AGBL4 ARFGEF2 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Leg predicted mass (right) 2.14 9 3 9.1 -0.49 1.8e-01 AC009228.1 AGBL4 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Arm fat mass (left) 2.26 9 4 12.1 -0.55 1.3e-01 AGBL4 ARL17A FOXO3 KANSL1 PIAS4 PTBP2 REEP5 TRPT1 ZMIZ2
Number of self-reported non-cancer illnesses 2.30 1 1 3.0 0.00 1.0e+00 SH2B3
Medication: Blood pressure 1.94 1 1 3.0 0.00 1.0e+00 SH2B3
Medication: Bendroflumethiazide 1.63 1 0 0.0 0.00 1.0e+00 SH2B3
Medication: Lisinopril 1.92 1 0 0.0 0.00 1.0e+00 SH2B3
Illnesses of father: High blood pressure 1.43 1 0 0.0 0.00 1.0e+00 SH2B3
Ever smoked 1.74 1 0 0.0 0.00 1.0e+00 SH2B3
Basal metabolic rate 2.31 8 5 15.2 -0.72 4.5e-02 AGBL4 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Leg fat percentage (left) 1.87 6 2 6.1 -0.60 2.1e-01 AGBL4 ARFGEF2 FOXO3 PIAS4 PTBP2 TRPT1
Arm fat-free mass (left) 2.38 8 5 15.2 -0.71 4.9e-02 AGBL4 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2
Number of operations (self-reported) 1.43 1 0 0.0 0.00 1.0e+00 FAM171A1
Diastolic blood pressure, automated reading 2.79 1 1 3.0 0.00 1.0e+00 SH2B3
Ever depressed for a whole week 1.24 1 0 0.0 0.00 1.0e+00 ARFGEF2
Vascular/heart problems diagnosed by doctor 2.43 4 1 3.0 -0.96 3.9e-02 OLA1 PIAS4 SH2B3 SPATS2L
Pain experienced in last month 1.50 1 0 0.0 0.00 1.0e+00 SH2B3
Heart attack/myocardial infarction (self-reported) 1.65 1 0 0.0 0.00 1.0e+00 SH2B3
Pack years of smoking 1.46 1 0 0.0 0.00 1.0e+00 AGBL4
Impedance of whole body 1.99 8 3 9.1 0.20 6.3e-01 ARL17A CCDC65 FOXO3 HBEGF IMMP1L NUCKS1 RMI1 SPATS2L
Leg fat mass (left) 2.30 7 3 9.1 -0.31 5.0e-01 AGBL4 FOXO3 KANSL1 PIAS4 PTBP2 REEP5 TRPT1
Arm predicted mass (left) 2.34 8 5 15.2 -0.71 4.9e-02 AGBL4 FOXO3 KANSL1 NUCKS1 PTBP2 REEP5 SH2B3 ZMIZ2

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 9 0.2578 1.94
GTEx Adipose Visceral Omentum 4 0.1965 1.96
GTEx Adrenal Gland 5 0.3432 2.09
GTEx Artery Aorta 9 0.3023 1.99
GTEx Artery Coronary 2 0.1691 1.98
GTEx Artery Tibial 9 0.2393 2.00
GTEx Brain Caudate basal ganglia 1 0.1087 1.89
GTEx Brain Cerebellar Hemisphere 3 0.2015 1.97
GTEx Brain Cerebellum 4 0.2018 2.00
GTEx Brain Cortex 3 0.2899 1.96
GTEx Brain Frontal Cortex BA9 3 0.3247 2.13
GTEx Brain Hippocampus 1 0.1908 2.01
GTEx Brain Hypothalamus 1 0.1695 1.91
GTEx Brain Nucleus accumbens basal ganglia 4 0.4624 2.12
GTEx Brain Putamen basal ganglia 1 0.1603 2.11
GTEx Breast Mammary Tissue 6 0.3040 2.02
GTEx Breast Mammary Tissue (Male) 2 0.1676 1.85
GTEx Breast Mammary Tissue (Female) 2 0.1217 1.95
GTEx Cells EBV-transformed lymphocytes 4 0.2811 1.89
GTEx Cells Transformed fibroblasts 5 0.1191 1.86
GTEx Colon Sigmoid 3 0.2052 2.05
GTEx Colon Transverse 6 0.2907 2.03
GTEx Esophagus Gastroesophageal Junction 5 0.3460 2.09
GTEx Esophagus Mucosa 9 0.2711 2.00
GTEx Esophagus Muscularis 10 0.3094 2.08
GTEx Heart Atrial Appendage 3 0.1900 2.05
GTEx Heart Left Ventricle 3 0.1961 2.11
GTEx Liver 5 0.6974 2.23
GTEx Lung 7 0.2436 2.02
GTEx Muscle Skeletal 9 0.3114 2.08
GTEx Nerve Tibial 14 0.3240 2.02
GTEx Ovary 4 0.4405 1.97
GTEx Pancreas 5 0.3064 1.96
GTEx Pituitary 7 0.6278 2.26
GTEx Prostate 4 0.4790 1.93
GTEx Skin Not Sun Exposed Suprapubic 9 0.3660 1.99
GTEx Skin Sun Exposed Lower leg 13 0.3571 2.05
GTEx Small Intestine Terminal Ileum 0 0.0000 1.87
GTEx Spleen 3 0.2126 2.01
GTEx Stomach 4 0.2751 1.92
GTEx Testis 12 0.3803 2.06
GTEx Thyroid 10 0.2501 1.96
GTEx Uterus 1 0.1764 1.72
GTEx Vagina 0 0.0000 1.95
GTEx Whole Blood 1 0.0502 2.01
METSIM Adipose 10 0.2169 1.92
NTR Blood 1 0.0416 1.72
ROSMAP Brain Pre-frontal Cortex 6 0.1366 1.96
YFS Blood 9 0.1949 1.80
CommonMind Brain Pre-frontal Cortex 10 0.1860 1.91
TCGA Breast Tumor 2 0.2608 1.88
TCGA Breast Normal 5 0.1188 1.69
TCGA Ovarian Tumor 9 0.3080 1.72
TCGA Prostate Tumor 8 0.2313 1.74