TWAS hub - MORF4L1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Nucleus accumbens basal ganglia	0.415	0.111	0.00078	0.044	NA	0.079	NA	0.062	0.0250	NA	0.0038	NA	0.00950
2	TCGA	Bladder Urothelial Carcinoma	0.038	0.023	0.00290	0.030	0.028	0.023	NA	0.035	0.0014	0.0019	0.0045	NA	0.00058

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pack years adult smoking proportion	19.3	29.4	42.6	-4.0	6.5
Pack years of smoking	18.2	26.7	36.8	-4.1	6.1
Angina (self-reported)	16.5	21.6	38.1	2.3	-6.2
Angina	15.6	20.5	35.5	2.4	-6.0
Coronary Artery Disease (CAD)	14.1	16.8	33.6	-0.2	-5.8
Illnesses of father: Heart disease	11.0	15.2	28.3	1.5	-5.3
Lung cancer (father)	9.8	11.4	18.5	-2.1	4.3
Heart disease (mother)	9.1	11.1	22.0	0.4	-4.7
Multivitamins +/- minerals	5.9	7.6	15.1	0.0	-3.9
Chronic bronchitis/emphysema (mother)	5.3	6.2	12.0	-0.6	3.5
Diverticular disease/diverticulitis (self-reported)	5.0	6.0	9.1	-3.0	-1.7
Heart disease (siblings)	4.6	5.7	10.8	0.7	-3.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.5	9.5	15.6	1.8	-4.0
Loud music exposure frequency	4.2	4.6	6.1	2.5	-1.8
Heart attack/myocardial infarction (self-reported)	4.2	5.4	6.6	2.1	-2.6
Alzheimer’s Disease (in mother)	4.1	4.7	8.2	-1.1	2.9
Vitamin and mineral supplements	3.9	5.3	9.2	-1.2	3.0
Heart attack	3.8	4.9	6.3	1.9	-2.5
Diabetes (mother)	3.6	4.6	4.8	2.2	-2.1
Hayfever/allergic rhinitis (self-reported)	3.6	4.8	5.1	2.3	-2.1
Illnesses of father: None of the above (group 1)	3.5	4.3	7.4	-1.1	2.7
LDL Cholesterol	3.4	5.3	8.8	3.0	1.4
Chronic bronchitis/emphysema (father)	3.4	4.0	8.0	-0.1	2.8
Myopia	3.4	4.9	5.3	2.3	-2.1
Medication: Bendroflumethiazide	3.3	5.1	9.7	-0.7	3.1
Average weekly fortified wine intake	3.2	3.7	7.0	-0.6	-2.7
Severe depression (siblings)	3.1	3.5	5.7	-1.1	-2.4
Mineral and other dietary supplements	3.0	4.0	7.0	1.0	2.6
Supplements: Glucosamine	2.9	3.8	6.6	1.0	-2.6
Diastolic blood pressure, automated reading	2.8	8.7	17.1	-0.5	4.1
Systolic Blood Pressure	2.7	13.6	26.1	-1.0	-5.1
Qualifications: NVQ or HND or HNC or equivalent	2.7	3.2	6.4	0.3	2.5
Medication: Gliclazide	2.7	3.0	5.1	-0.9	2.3
Mouth/teeth dental problems: Dentures	2.5	4.2	5.2	-1.8	2.3
Medication: Seretide 50 evohaler	2.5	2.9	5.8	2.4	0.3
Risk taking	2.5	3.6	4.5	1.7	-2.1
Ever smoked	2.4	4.1	7.8	2.8	0.7
Type 2 Diabetes (T2D) (2012)	2.3	2.6	4.2	1.0	-2.1
High blood pressure (mother)	2.3	3.2	4.5	1.3	-2.1
Smoking status: Previous	2.2	3.2	6.3	2.5	0.4
Age when periods started (menarche)	2.1	4.9	8.7	2.9	-1.1
Past tobacco smoking	2.1	3.9	6.5	-2.5	-1.2
Length of working week for main job	2.1	2.3	4.6	-0.1	-2.1
Eye problems/disorders: None of the above	2.1	2.4	4.7	-0.5	-2.2
Mood swings	2.1	3.8	7.5	0.1	-2.7
Medication: Blood pressure	2.1	4.0	4.8	-1.8	2.2
Illnesses of father: High blood pressure	2.1	2.6	2.9	-1.7	-1.5
Major Depression (MDD)	2.0	2.4	4.3	-0.7	-2.1
Birth weight	2.0	4.2	7.8	-2.8	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.2	4.1	0.5	-2.0
Systolic blood pressure, automated reading	1.9	5.5	10.8	-0.5	-3.3
Leg pain on walking	1.9	2.4	2.7	-1.4	-1.6
Ovarian Cancer	1.8	2.4	2.9	1.7	-1.4
Ever used hormone-replacement therapy (HRT)	1.8	2.3	4.4	-0.5	2.1
Supplements: Zinc	1.8	2.0	3.0	1.7	-1.0
Medication: Atenolol	1.8	2.3	4.0	0.7	-2.0
Had menopause	1.8	2.2	4.4	0.0	2.1
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.0	2.5	-1.2	-1.6
Medication: Amlodipine	1.8	2.5	4.9	0.2	2.2
Chest pain or discomfort	1.8	2.6	5.1	-0.2	-2.3
Medication: Aspirin	1.8	2.3	2.9	1.4	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	3.7	-0.6	-1.9
Pain type(s) experienced in last month: Hip pain	1.8	2.3	2.7	1.6	-1.4
Alzheimer’s Disease (including proxy)	1.7	2.5	4.5	-0.7	2.1
Smoking Status	1.7	4.1	7.5	2.7	0.9
Eye problems/disorders: Diabetes related eye disease	1.7	1.8	3.6	0.3	1.9
Sitting height	1.7	12.2	13.7	-3.3	-3.7
Waist Hip Ratio (WHR)	1.5	6.6	11.8	3.4	-1.1
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	3.6	-1.0	-1.9
Eye problems/disorders: Cataract	1.5	1.7	2.9	0.8	1.7
Commuting to job workplace: Public transport	1.5	1.8	2.9	-0.8	-1.7
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	2.2	-1.5	-1.2
Pain all over the body in last month	1.4	1.5	3.0	-0.1	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	2.5	-1.6	-1.0
Medication: Ibuprofen	1.4	1.6	3.3	0.1	-1.8
Had major operations	1.4	1.7	2.0	-1.4	-1.2
Number of operations (self-reported)	1.4	2.0	3.8	-1.9	-0.5
Townsend deprivation index at recruitment	1.3	1.8	2.0	1.4	1.3
Birth weight of first child	1.3	2.3	4.3	-2.1	-0.6
Emphysema/chronic bronchitis	1.3	1.4	2.2	-0.8	1.5
Migraine (self-reported)	1.3	1.6	2.9	-1.7	0.6
Commuting to job workplace: Car/motor vehicle	1.3	1.5	2.4	0.7	1.6
Back pain experienced in last month	1.3	1.9	3.8	-0.1	-1.9
Osteoarthritis (self-reported)	1.3	1.6	1.7	1.3	1.3
Supplements: Fish oil (including cod liver oil)	1.3	1.7	1.9	-1.4	-1.2
Qualifications: CSEs or equivalent	1.2	1.5	3.1	0.1	1.7
Illnesses of mother	1.2	1.5	3.0	-0.0	1.7
Hair/balding pattern: Pattern 4	1.2	3.0	4.3	1.3	2.1
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	2.9	-0.5	-1.7
Forced vital capacity (FVC), Best measure	1.2	4.3	8.2	0.6	-2.9
Health satisfaction	1.2	1.5	2.3	-1.5	0.8
Medication for cholesterol	1.2	1.8	2.7	1.0	-1.6
Medication: Aspirin	1.2	1.6	1.8	1.1	-1.4
Bipolar Disorder (2011)	1.1	1.1	2.1	-1.5	-0.2
Triglycerides	1.1	1.7	1.8	1.3	1.3
Worrier / anxious feelings	1.1	2.2	3.5	-0.9	-1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	2.6	-1.6	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	4.4	-0.2	-2.1
Diabetes diagnosed by doctor	1.1	1.8	3.5	-0.4	1.9
Qualifications: nursing, teaching	1.1	1.6	2.4	-1.5	-1.0
Irritability	1.1	1.9	3.7	0.3	-1.9
Unable to work because of sickness or disability	1.1	1.4	2.8	0.2	1.7
Intelligence (Savage-Jansen 2018)	1.0	3.1	5.0	2.2	-1.1
Average weekly spirits intake	1.0	1.3	2.4	1.6	0.3
Relative age voice broke	1.0	1.5	1.8	-1.4	1.1
Number of live births	1.0	1.4	1.9	-1.4	0.9
Pulse rate	1.0	1.7	2.8	-0.7	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	5.8	0.6	-2.4
Pulse rate, automated reading	1.0	3.3	6.3	0.6	2.5
Average weekly red wine intake	1.0	1.5	2.9	0.5	-1.7
High cholesterol (Self-reported)	1.0	1.8	2.1	1.5	1.2
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.4	-1.6	-0.0
Pain experienced in last month	1.0	1.7	3.3	-1.8	0.3
Supplements: Calcium	1.0	1.1	2.2	-0.0	-1.5
Schizophrenia vs Biploar Disorder	0.9	1.2	1.2	-1.1	1.1
Rheumatoid Arthritis	0.9	1.2	2.2	1.5	-0.5
Lung FVC	0.9	4.5	8.1	2.9	-1.0
Hayfever, allergic rhinitis or eczema	0.9	1.9	3.3	0.7	-1.8
Pulse wave reflection index	0.9	1.1	1.4	-1.2	0.8
Shortness of breath walking on level ground	0.9	1.0	1.3	-0.9	1.1
Breast cancer (self-reported)	0.9	1.0	2.0	-0.2	-1.4
Basal cell carcinoma (self-reported)	0.9	1.1	2.1	-0.3	1.4
Sensitivity / hurt feelings	0.8	1.3	1.5	-1.1	-1.2
Hearing difficulty/problems: Yes	0.8	1.2	1.2	-1.1	-1.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.6	0.3	1.3
Number of incorrect matches in round	0.8	1.4	2.3	-1.5	0.7
Qualifications: College or University degree	0.8	2.5	2.6	-1.6	-1.5
Medication for pain relief, constipation, heartburn	0.8	1.4	2.8	0.1	1.7
Neck or shoulder pain in last month	0.8	1.1	1.4	1.2	-0.9
Age at last live birth	0.8	1.1	1.2	1.1	1.0
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	1.8	0.3	1.4
Average weekly champagne plus white wine intake	0.8	1.1	2.1	1.5	-0.4
Fractured/broken bones in last 5 years	0.8	1.0	1.7	-0.5	-1.3
Alzheimer’s Disease (in father)	0.7	0.8	1.5	-1.2	0.3
HbA1C	0.7	0.8	1.6	1.2	-0.2
Neuroticism (2016)	0.7	1.0	1.8	-0.4	-1.4
Respiratory disease	0.7	1.6	2.4	0.9	1.5
Hand grip strength (left)	0.7	1.9	3.6	-1.9	-0.5
Hand grip strength (right)	0.7	1.9	2.0	-1.4	-1.4
Maternal smoking around birth	0.7	1.0	1.3	1.1	0.8
Serious illness, injury or assault to yourself	0.7	0.9	1.2	0.7	-1.1
Hair/balding pattern: Pattern 2	0.7	0.9	1.4	-1.2	-0.7
Forced vital capacity (FVC)	0.7	2.7	5.5	0.1	-2.3
Financial difficulties in last 2 years	0.7	0.9	1.6	0.4	-1.3
Mouth/teeth dental problems	0.7	1.0	2.0	1.4	-0.2
Medication: Simvastatin	0.7	1.0	1.1	0.9	1.1
Medication: Cholesterol lowering	0.7	1.1	2.2	1.5	-0.2
Exposure to tobacco smoke at home	0.7	0.8	1.6	0.1	-1.3
Alcohol intake frequency.	0.7	1.7	2.2	-1.5	1.0
Knee pain experienced in last month	0.7	1.1	2.2	0.2	-1.5
Mean Putamen Volume	0.6	0.7	1.2	0.3	-1.1
Primary Biliary Cirrhosis	0.6	0.8	1.3	0.5	1.1
Hypothyroidism (self reported)	0.6	1.3	1.8	-1.4	0.9
Relative age of first facial hair	0.6	1.3	2.0	0.8	-1.4
Medication: Metformin	0.6	0.8	1.6	0.3	1.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	1.4	-0.4	-1.2
Neuroticism score	0.6	1.3	2.1	-0.7	-1.5
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	4.3	-0.1	-2.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.3	-0.3	-1.2
Leg fat percentage (right)	0.6	2.0	2.3	1.3	1.5
Number of children fathered	0.6	0.6	1.2	-1.1	-0.2
Arm predicted mass (right)	0.6	2.9	5.8	-2.4	-0.0
Hypertension (Self-reported)	0.6	1.8	2.0	-1.4	1.2
Ever had bowel cancer screening	0.6	0.8	1.0	-0.7	1.0
Cholesterol lowering medication	0.6	0.9	1.0	-1.0	0.8
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	0.8	-0.9	-0.8
Verbal and Numeric Reasoning (VNR)	0.5	1.2	2.2	1.5	-0.5
Ulcerative Colitis	0.5	0.7	1.0	-0.6	1.0
Blood Platelet Count	0.5	5.6	11.3	-0.0	-3.4
Ever had hysterectomy (womb removed)	0.5	0.5	1.0	-1.0	0.2
Impedance of leg (right)	0.5	2.6	5.0	2.2	-0.4
Current tobacco smoking	0.5	0.8	0.9	0.9	1.0
Medication: Levothyroxine sodium	0.5	0.8	1.5	-0.3	1.2
Impedance of leg (left)	0.5	2.3	4.5	2.1	-0.4
Had other major operations	0.5	0.6	1.1	-0.2	-1.0
Noisy workplace	0.5	0.6	1.0	-0.5	-1.0
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.0	0.6	-1.4
Tense / ‘highly strung’	0.5	0.8	1.6	0.1	-1.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.0	-1.0	-0.8
Body fat percentage	0.5	1.8	1.9	1.4	1.3
Exposure to tobacco smoke outside home	0.5	0.7	1.1	0.5	-1.1
Wheeze or whistling in the chest in last year	0.5	0.9	1.7	-0.5	1.3
Medication: Blood pressure	0.5	0.8	1.4	0.4	1.2
Number of full sisters	0.5	0.6	1.1	-0.3	1.1
Family relationship satisfaction	0.5	0.6	0.6	0.8	-0.7
Supplements: Vitamin C	0.5	0.6	0.8	0.7	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.2	-0.2	1.1
Leg fat-free mass (right)	0.5	2.5	4.8	-2.2	-0.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	0.6	0.7	0.8
Friendships satisfaction	0.5	0.6	1.2	0.3	-1.1
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.1	-1.0	-0.4
Medication: Atorvastatin	0.5	0.6	1.2	0.2	-1.1
Leg fat percentage (left)	0.5	1.7	2.2	1.1	1.5
Prostate Cancer	0.4	0.5	1.0	1.0	-0.2
Age at First Birth	0.4	0.6	0.9	0.9	0.6
Cardiovascular Disease	0.4	1.2	2.4	0.1	1.6
Neuroticism	0.4	0.9	1.8	0.4	-1.3
Leg fat-free mass (left)	0.4	1.9	3.7	-1.9	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	0.9	1.0	0.2
High blood pressure	0.4	1.2	1.9	-1.4	0.7
Alcohol usually taken with meals	0.4	0.6	0.7	-0.7	-0.8
Allergy	0.4	0.9	1.3	-1.2	0.6
Diabetes (self-reported)	0.4	0.6	1.2	-0.1	1.1
Fluid intelligence score	0.4	0.8	1.4	1.2	-0.4
Impedance of arm (right)	0.4	2.0	4.0	2.0	0.1
Arm fat percentage (right)	0.4	1.7	2.6	0.9	1.6
Trunk fat-free mass	0.4	2.3	4.5	-2.1	-0.2
Hip circumference	0.4	1.6	1.9	-1.1	1.4
Alcohol intake versus 10 years previously	0.4	0.7	1.2	0.4	-1.1
Trunk predicted mass	0.4	2.3	4.5	-2.1	-0.2
Standing height	0.4	3.8	4.7	-2.2	-1.7
Blood clot in the leg (DVT)	0.4	0.5	0.7	-0.5	-0.8
Arm fat-free mass (right)	0.4	1.8	3.7	-1.9	0.1
Number of full brothers	0.4	0.5	1.0	0.1	1.0
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.7	0.8	0.6
Mean time to correctly identify matches	0.4	0.8	1.3	-0.5	1.2
Whole body fat-free mass	0.4	2.4	4.8	-2.2	-0.1
Whole body water mass	0.4	2.5	5.1	-2.3	-0.1
Leg predicted mass (right)	0.4	2.1	4.1	-2.0	-0.2
Guilty feelings	0.4	0.6	1.3	-0.0	-1.1
Mother’s age at death	0.4	0.5	0.9	1.0	-0.0
Medication: Lisinopril	0.4	0.6	0.6	0.8	0.8
Arm fat-free mass (left)	0.4	2.3	4.5	-2.1	0.2
Impedance of whole body	0.4	2.3	4.5	2.1	-0.3
Arm predicted mass (left)	0.4	1.8	3.5	-1.9	0.3
Depressed Affect (Nagel 2018)	0.3	0.6	0.8	0.6	-0.9
Neuroticism (Nagel 2018)	0.3	0.7	1.4	0.3	-1.2
Reaction Time	0.3	0.6	1.1	-1.0	0.3
Body Mass Index (BMI) (2010)	0.3	0.4	0.7	0.1	-0.8
Allergy or Eczema	0.3	0.9	1.1	0.8	-1.1
Number of treatments/medications taken	0.3	0.5	0.9	0.4	0.9
Medication for hormone replacement therapy	0.3	0.3	0.5	0.7	0.4
Trunk fat percentage	0.3	1.4	1.8	1.3	1.0
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.8	0.0	-0.9
Stomach or abdominal pain in last month	0.3	0.4	0.8	-0.2	-0.9
Leg predicted mass (left)	0.3	1.8	3.7	-1.9	-0.2
Waist circumference	0.3	0.9	1.1	1.1	0.9
Father’s age at death	0.3	0.4	0.8	-0.0	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.9	-0.9	-0.3
Hair/balding pattern: Pattern 3	0.3	0.5	0.7	-0.5	0.8
Depression (self-reported)	0.3	0.4	0.7	-0.3	0.9
Impedance of arm (left)	0.3	1.2	2.2	1.5	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.8	-0.9	-0.3
Gout (self-reported)	0.3	0.4	0.7	0.0	0.8
Comparative body size at age 10	0.3	0.9	1.8	-0.3	1.4
Leg fat mass (right)	0.3	1.1	1.6	0.8	1.3
Arm fat percentage (left)	0.3	1.3	2.0	0.8	1.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.0	-0.2	-1.0
Asthma (self-reported)	0.3	0.6	1.1	0.2	1.0
Smoking status: Current	0.3	0.5	0.9	0.9	0.2
Miserableness	0.3	0.5	1.0	-1.0	-0.2
Financial situation satisfaction	0.3	0.4	0.4	-0.6	-0.6
Medication: Paracetamol	0.3	0.5	0.8	0.4	-0.9
Basal metabolic rate	0.3	1.7	3.4	-1.9	-0.1
Alcohol drinker status: Previous	0.3	0.3	0.7	-0.8	-0.1
Ulcerative Colitis (UC)	0.2	0.3	0.6	0.3	0.8
Breast Cancer	0.2	0.5	0.7	0.8	-0.5
Schizophrenia (2014)	0.2	0.5	0.6	-0.8	0.6
Blood Red Count	0.2	1.7	3.0	1.7	0.7
Blood White Count	0.2	1.5	2.6	1.6	-0.7
Medication: Co-codamol	0.2	0.3	0.5	0.7	0.1
Taking other prescription medications	0.2	0.3	0.4	-0.7	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.1	-1.0	-0.1
Hearing difficulty/problems with background noise	0.2	0.4	0.6	-0.8	0.4
Qualifications: None of the above	0.2	0.5	1.0	-0.1	-1.0
Medication: Ramipril	0.2	0.2	0.3	-0.3	0.6
Illnesses of siblings	0.2	0.3	0.3	0.6	0.6
Time employed in main current job	0.2	0.2	0.2	-0.4	-0.5
Asthma	0.2	0.5	1.0	0.0	1.0
Arm fat mass (right)	0.2	1.0	1.9	0.2	1.4
Headache pain in last month	0.2	0.4	0.6	0.8	0.3
Glaucoma (self-reported)	0.2	0.2	0.3	-0.4	0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.5	-0.4	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.6	0.7	0.2
Age at first live birth	0.2	0.3	0.4	-0.6	-0.4
Whole body fat mass	0.2	0.8	1.3	0.6	1.1
Illnesses of siblings: Diabetes	0.2	0.2	0.2	-0.4	-0.5
Loneliness, isolation	0.2	0.3	0.4	0.6	0.4
Osteoporosis (self-reported)	0.2	0.2	0.3	0.6	-0.3
Arm fat mass (left)	0.2	0.8	1.7	-0.0	1.3
Number of self-reported non-cancer illnesses	0.2	0.4	0.7	-0.2	0.8
Leg fat mass (left)	0.2	1.0	1.7	0.5	1.3
Bipolar Disorder (2018)	0.1	0.1	0.2	-0.1	0.4
Bipolar Disorder or Schizophrenia	0.1	0.2	0.4	-0.1	0.7
Schizophrenia (2018)	0.1	0.1	0.3	-0.0	0.5
Worry (Nagel 2018)	0.1	0.1	0.1	0.3	-0.4
Crohns Disease (2017)	0.1	0.3	0.5	0.7	0.2
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	0.7	0.4
Crohns Disease (2012)	0.1	0.1	0.2	-0.4	0.1
Fasting Glucose	0.1	0.1	0.1	0.3	0.2
HDL Cholesterol	0.1	0.1	0.2	0.2	-0.4
Lupus	0.1	0.1	0.1	0.4	0.3
Blood Eosinophil Count	0.1	1.0	1.7	1.3	-0.6
BMI	0.1	0.6	1.1	-0.2	1.0
Height	0.1	2.5	3.7	-1.9	-1.1
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.5	0.7	0.2
Tanning	0.1	0.6	0.8	0.9	0.7
Diabetes (father)	0.1	0.1	0.2	-0.4	0.1
Body mass index (BMI)	0.1	0.6	1.2	0.1	1.1
Trunk fat mass	0.1	0.6	0.7	0.8	0.8
Nervous feelings	0.1	0.1	0.1	-0.4	0.3
Weight	0.1	0.4	0.8	-0.9	0.3
Happiness	0.1	0.1	0.2	0.5	0.1
Medication: Lansoprazole	0.1	0.2	0.2	-0.5	0.3
Prospective memory result	0.1	0.1	0.2	-0.5	-0.1
Pulse wave Arterial Stiffness index	0.1	0.1	0.2	-0.0	-0.4
Breastfed as a baby	0.1	0.1	0.1	0.4	-0.3
Peak expiratory flow (PEF)	0.1	0.2	0.4	-0.6	0.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	0.5	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.1	-0.2	0.3
High blood pressure (siblings)	0.1	0.1	0.3	-0.5	-0.1
Worry too long after embarrassment	0.1	0.2	0.4	0.1	-0.6
Pulse wave peak to peak time	0.1	0.1	0.1	-0.2	0.3
Comparative height size at age 10	0.1	0.6	0.9	-1.0	-0.5
Overall health rating	0.1	0.3	0.6	-0.1	0.8
Long-standing illness, disability or infirmity	0.1	0.2	0.3	-0.5	-0.4
Commuting to job workplace: Walk	0.1	0.1	0.2	0.4	-0.3
Wears glasses or contact lenses	0.1	0.1	0.2	0.4	0.0
Ever taken oral contraceptive pill	0.1	0.1	0.3	0.2	-0.5
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	0.3	-0.4
Average weekly beer plus cider intake	0.1	0.2	0.4	-0.6	0.1
Commuting to job workplace: Cycle	0.1	0.1	0.3	-0.5	0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.3	-0.6	0.1
Depression (Nagel 2018)	0.0	0.0	0.0	-0.0	0.0
Heel T-Score	0.0	0.2	0.3	-0.5	0.2
Lung FEV1/FVC ratio	0.0	0.2	0.2	0.5	0.5
Chronotype (morning person)	0.0	0.0	0.0	0.2	0.0
Hair Pigment	0.0	1.2	2.1	-0.5	-1.4
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.0	-0.1	-0.2
Fed-up feelings	0.0	0.0	0.0	-0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.2	-0.5	-0.1
Falls in the last year	0.0	0.0	0.1	-0.3	0.0
Qualifications: O levels/GCSEs or equivalent	0.0	0.1	0.1	-0.4	0.2
Medication: Paracetamol	0.0	0.1	0.1	0.3	-0.2
Medication: Allopurinol	0.0	0.0	0.0	0.1	0.1
Medication: Omeprazole	0.0	0.0	0.1	0.2	0.2
Suffer from ‘nerves’	0.0	0.1	0.1	-0.3	0.3
Hearing aid user	0.0	0.0	0.0	-0.0	0.1
Alcohol drinker status: Never	0.0	0.0	0.0	0.1	0.0
Age started oral contraceptive pill	0.0	0.0	0.0	-0.2	0.2
Ever depressed for a whole week	0.0	0.0	0.0	0.0	0.2
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.2	0.4	-0.1

Hub : Genes

MORF4L1

Models

Trait associations