TWAS hub - PHC3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0818	0.0187	5.6e-16	0.066	0.056	0.062	0.067	0.067	8.1e-21	8.5e-18	1.5e-19	4.9e-21	5.6e-21
2	TCGA	Breast Invasive Carcinoma	0.0427	0.0292	1.3e-03	0.014	0.007	0.004	NA	0.007	4.9e-04	9.8e-03	3.9e-02	NA	9.7e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Prostate Cancer	29.0	40.8	51.3	7.2	5.5
Heart disease (siblings)	4.9	6.1	6.4	2.5	2.4
Frequency of tenseness / restlessness in last 2 weeks	4.6	7.2	7.6	-2.6	-2.8
Loud music exposure frequency	4.6	5.0	5.2	2.3	2.2
Major Depression (MDD)	4.5	5.4	6.2	2.5	2.2
Eye problems/disorders: None of the above	4.5	5.2	6.8	-1.9	-2.6
Serious illness, injury or assault to yourself	4.4	5.3	5.6	2.2	2.4
Diabetes (mother)	4.1	5.3	6.3	2.1	2.5
Falls in the last year	4.0	5.4	5.5	2.3	2.4
Osteoarthritis (self-reported)	4.0	5.2	5.4	2.3	2.2
Guilty feelings	3.7	5.6	6.7	-2.1	-2.6
Blood Eosinophil Count	3.6	27.6	31.4	4.9	5.6
Illnesses of father: High blood pressure	3.5	4.4	5.2	-1.9	-2.3
Average weekly fortified wine intake	3.4	4.0	4.3	1.9	2.1
Illness, injury, bereavement, stress in last 2 years	3.3	4.0	4.1	-2.0	-2.0
Friendships satisfaction	3.2	4.0	4.1	2.0	1.9
Eye problems/disorders: Cataract	3.0	3.5	5.4	1.3	2.3
Medication: Levothyroxine sodium	2.9	4.9	5.5	2.1	2.3
HDL Cholesterol	2.6	4.4	5.2	-2.3	-1.9
Financial difficulties in last 2 years	2.6	3.5	3.5	1.8	1.9
Pain all over the body in last month	2.5	2.7	3.5	-1.4	-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	2.9	3.0	-1.7	-1.7
Commuting to job workplace: Walk	2.5	2.7	3.2	-1.8	-1.5
Illnesses of siblings	2.4	3.4	3.7	-1.8	-1.9
Risk taking	2.4	3.5	4.5	1.6	2.1
Heel T-Score	2.2	17.1	17.5	-4.1	-4.2
Suffer from ‘nerves’	2.2	3.4	3.7	-1.8	-1.9
Smoking status: Current	2.2	3.5	3.5	1.9	1.9
Worry too long after embarrassment	2.1	3.5	3.5	-1.9	-1.9
Emphysema/chronic bronchitis	2.1	2.4	3.1	1.8	1.3
Ever used hormone-replacement therapy (HRT)	2.0	2.6	3.7	1.2	1.9
Medication: Atenolol	2.0	2.5	3.0	1.7	1.4
Alcohol intake frequency.	2.0	4.7	4.8	2.2	2.1
Bipolar Disorder (2018)	1.9	3.1	4.0	-2.0	-1.5
Current tobacco smoking	1.9	3.2	3.3	1.8	1.8
Family relationship satisfaction	1.9	2.4	2.7	1.6	1.4
Osteoporosis (self-reported)	1.8	2.3	2.4	1.6	1.5
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	2.6	1.6	1.4
Medication: Lansoprazole	1.7	2.0	2.0	1.4	1.4
Long-standing illness, disability or infirmity	1.7	2.6	2.8	1.6	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.7	3.8	-2.0	-1.9
Had menopause	1.6	2.0	2.7	1.2	1.6
Medication: Allopurinol	1.6	2.1	2.1	-1.4	-1.5
Medication: Omeprazole	1.6	1.9	2.2	-1.5	-1.3
Lung FVC	1.5	7.6	8.4	-2.9	-2.6
Blood clot in the leg (DVT)	1.5	1.9	2.0	1.4	1.4
Back pain experienced in last month	1.5	2.2	2.4	1.4	1.6
Deep venous thrombosis (DVT) (self-reported)	1.5	2.0	2.0	1.4	1.4
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	3.9	-1.5	-2.0
Neuroticism score	1.4	3.0	3.3	-1.6	-1.8
Time employed in main current job	1.4	1.6	2.0	-1.1	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.4	4.8	-2.2	-2.0
Gout (self-reported)	1.4	1.9	2.1	-1.3	-1.5
Illnesses of father: Heart disease	1.4	1.9	2.0	1.4	1.3
Ever taken oral contraceptive pill	1.4	1.6	1.7	1.2	1.3
Number of operations (self-reported)	1.4	2.2	2.7	1.3	1.6
Myopia	1.4	2.0	2.4	-1.3	-1.5
Hayfever, allergic rhinitis or eczema	1.3	2.9	3.4	-1.9	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.3	2.9	3.2	-1.6	-1.8
Tense / ‘highly strung’	1.3	2.1	2.5	-1.3	-1.6
Hair/balding pattern: Pattern 4	1.3	3.2	4.6	-1.3	-2.1
Exposure to tobacco smoke outside home	1.3	1.7	1.8	1.3	1.3
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	2.1	1.0	1.5
Coronary Artery Disease (CAD)	1.2	1.4	1.5	-1.2	-1.1
Triglycerides	1.2	1.9	2.0	1.4	1.4
Medication for hormone replacement therapy	1.2	1.3	2.1	-1.4	-0.7
Heart attack	1.2	1.6	1.8	1.4	1.1
Forced vital capacity (FVC), Best measure	1.2	4.5	4.7	-2.2	-2.1
Medication: Blood pressure	1.2	2.1	2.1	1.4	1.5
Financial situation satisfaction	1.2	1.4	1.9	1.0	1.4
Ovarian Cancer	1.1	1.5	1.7	-1.3	-1.1
Nervous feelings	1.1	2.1	2.5	-1.6	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	2.5	1.0	1.6
Chest pain or discomfort	1.1	1.6	1.8	1.3	1.2
Wears glasses or contact lenses	1.1	1.3	1.3	1.1	1.1
Bipolar Disorder (2011)	1.0	1.0	2.0	-1.4	0.0
Average weekly spirits intake	1.0	1.2	1.6	1.3	0.9
Taking other prescription medications	1.0	1.5	2.2	0.9	1.5
Forced expiratory volume in 1-second (FEV1)	1.0	3.2	3.2	-1.8	-1.8
Happiness	1.0	1.3	1.4	1.1	1.2
Medication: Paracetamol	1.0	1.7	1.7	-1.3	-1.3
Age at first live birth	1.0	1.8	2.4	-1.1	-1.5
Father’s age at death	0.9	1.2	1.6	-1.3	-0.9
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	1.7	-1.1	-1.3
Qualifications: College or University degree	0.9	2.9	3.0	-1.7	-1.7
Knee pain experienced in last month	0.9	1.3	1.6	1.0	1.3
Qualifications: nursing, teaching	0.9	1.3	1.5	-1.2	-1.1
Heart attack/myocardial infarction (self-reported)	0.9	1.2	1.4	1.2	1.0
LDL Cholesterol	0.8	1.2	1.5	1.0	1.2
Noisy workplace	0.8	1.0	1.1	-1.1	-1.0
Glaucoma (self-reported)	0.8	1.0	1.1	-1.0	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.0	0.9	1.0
Supplements: Vitamin C	0.8	1.0	1.1	-0.9	-1.1
Handedness (chirality/laterality): Left-handed	0.8	0.9	1.1	-0.9	-1.1
Diabetes diagnosed by doctor	0.8	1.4	1.7	1.3	1.0
Unable to work because of sickness or disability	0.8	1.0	1.3	1.2	0.8
Crohns Disease (2012)	0.7	1.2	1.2	1.1	1.1
Mean Putamen Volume	0.7	0.8	0.9	-0.9	-0.9
Cardiovascular Disease	0.7	2.2	2.3	1.4	1.5
High blood pressure	0.7	2.0	2.1	1.4	1.5
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	1.7	0.9	1.3
Overall health rating	0.7	1.5	1.7	1.2	1.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	1.3	-1.1	-0.9
Medication: Bendroflumethiazide	0.7	1.0	1.7	0.6	1.3
Medication: Lisinopril	0.7	0.9	1.1	0.9	1.0
Alcohol drinker status: Never	0.7	0.9	1.4	0.5	1.2
Bipolar Disorder or Schizophrenia	0.6	1.4	1.4	-1.2	-1.2
Number of treatments/medications taken	0.6	1.1	1.5	0.8	1.2
Diabetes (father)	0.6	0.7	0.8	0.9	0.8
Qualifications: CSEs or equivalent	0.6	0.8	1.0	0.7	1.0
Forced vital capacity (FVC)	0.6	2.4	2.7	-1.5	-1.7
Qualifications: None of the above	0.6	1.2	1.8	1.3	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.0	0.7	1.0
Prospective memory result	0.6	0.7	1.2	-0.5	-1.1
Lung cancer (father)	0.6	0.7	1.0	0.6	1.0
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.2	1.1	0.4
Health satisfaction	0.6	0.7	0.8	0.8	0.9
Mean time to correctly identify matches	0.6	1.1	1.5	-1.2	-0.8
Commuting to job workplace: Public transport	0.6	0.7	0.9	0.7	1.0
Pain experienced in last month	0.6	1.0	1.1	0.9	1.1
Alcohol drinker status: Previous	0.6	0.6	0.9	0.9	0.6
Reaction Time	0.5	1.0	1.4	-1.2	-0.7
Fasting Glucose	0.5	0.6	0.6	-0.7	-0.8
Primary Biliary Cirrhosis	0.5	0.8	1.0	1.0	0.7
Allergy or Eczema	0.5	1.3	1.8	-1.3	-0.9
Neuroticism	0.5	1.3	1.3	-1.2	-1.1
Trunk fat percentage	0.5	2.1	2.1	1.5	1.5
Townsend deprivation index at recruitment	0.5	0.7	0.8	0.8	0.9
Age when periods started (menarche)	0.5	1.1	1.1	-1.1	-1.0
Alcohol intake versus 10 years previously	0.5	0.8	0.9	1.0	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.1	-0.7	-1.0
Peak expiratory flow (PEF)	0.5	1.2	1.5	-1.2	-1.0
Had major operations	0.5	0.6	0.8	0.6	0.9
Smoking status: Previous	0.5	0.7	0.9	0.7	1.0
Eye problems/disorders: Glaucoma	0.5	0.6	0.8	-0.9	-0.7
Ever smoked	0.5	0.8	1.3	0.5	1.1
Vascular/heart problems diagnosed by doctor	0.5	1.4	1.5	-1.2	-1.2
Verbal and Numeric Reasoning (VNR)	0.4	1.0	1.5	1.2	0.7
Smoking Status	0.4	0.9	1.1	0.9	1.1
Lung FEV1/FVC ratio	0.4	2.1	2.4	-1.6	-1.3
Systolic blood pressure, automated reading	0.4	1.2	1.7	1.3	0.9
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	0.8	0.9	0.4
High blood pressure (mother)	0.4	0.6	0.6	0.7	0.8
Past tobacco smoking	0.4	0.8	1.1	-0.7	-1.0
Trunk fat-free mass	0.4	2.2	2.5	-1.6	-1.4
Hair/balding pattern: Pattern 3	0.4	0.6	0.8	0.6	0.9
Trunk predicted mass	0.4	2.2	2.5	-1.6	-1.4
Breastfed as a baby	0.4	0.5	0.6	-0.6	-0.8
Number of full brothers	0.4	0.5	0.6	0.6	0.8
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.7	0.8	0.5
Hypertension (Self-reported)	0.4	1.1	1.4	1.0	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	0.9	-0.9	-0.8
Ever had bowel cancer screening	0.4	0.5	0.5	-0.7	-0.7
Irritability	0.4	0.7	0.7	-0.8	-0.8
Ever depressed for a whole week	0.4	0.5	0.8	-0.9	-0.5
Commuting to job workplace: Cycle	0.4	0.5	0.6	-0.6	-0.8
Rheumatoid Arthritis	0.3	0.4	0.5	0.7	0.5
Blood White Count	0.3	2.3	2.6	1.4	1.6
Systolic Blood Pressure	0.3	1.7	2.0	1.4	1.1
Hair Pigment	0.3	7.3	8.0	-2.6	-2.8
Medication: Co-codamol	0.3	0.4	0.4	0.6	0.6
Medication: Metformin	0.3	0.5	0.7	-0.5	-0.8
Stomach or abdominal pain in last month	0.3	0.3	0.4	0.4	0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.6	-0.4	-0.8
Medication: Simvastatin	0.3	0.4	0.5	0.7	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.6	0.2	0.8
Length of working week for main job	0.3	0.3	0.6	-0.8	-0.1
Medication: Amlodipine	0.3	0.4	0.4	0.6	0.6
Body fat percentage	0.3	1.3	1.3	1.2	1.1
Number of children fathered	0.3	0.4	0.5	-0.4	-0.7
Shortness of breath walking on level ground	0.3	0.4	0.4	-0.6	-0.5
Medication: Ibuprofen	0.3	0.3	0.5	0.3	0.7
Heart disease (mother)	0.3	0.4	0.4	0.6	0.6
Leg pain on walking	0.3	0.4	0.7	-0.8	-0.2
Medication: Aspirin	0.3	0.3	0.6	0.8	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.5	0.4	0.7
Hearing aid user	0.3	0.4	0.4	-0.6	-0.6
Medication: Blood pressure	0.3	0.6	0.6	0.7	0.8
Medication: Paracetamol	0.3	0.5	0.6	-0.8	-0.6
Intelligence (Savage-Jansen 2018)	0.2	0.5	0.7	0.9	0.6
Alzheimer’s Disease (including proxy)	0.2	0.2	0.4	0.7	0.1
Age at First Birth	0.2	0.3	0.4	-0.5	-0.6
Ulcerative Colitis	0.2	0.4	0.4	0.6	-0.5
Height	0.2	4.6	6.2	-2.5	-1.7
Hypothyroidism (self reported)	0.2	0.5	0.9	0.4	0.9
Hearing difficulty/problems: Yes	0.2	0.3	0.3	0.5	0.5
Ever had hysterectomy (womb removed)	0.2	0.2	0.3	0.1	0.6
Pack years adult smoking proportion	0.2	0.3	0.3	-0.6	-0.5
Hand grip strength (right)	0.2	0.5	0.8	-0.5	-0.9
Maternal smoking around birth	0.2	0.3	0.5	0.7	0.3
Relative age voice broke	0.2	0.3	0.5	-0.3	-0.7
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.4	0.4	0.6
Supplements: Glucosamine	0.2	0.2	0.4	-0.6	-0.2
Trunk fat mass	0.2	0.9	1.0	0.9	1.0
Alcohol usually taken with meals	0.2	0.3	0.5	-0.7	-0.3
Hair/balding pattern: Pattern 2	0.2	0.3	0.6	-0.8	-0.2
Number of live births	0.2	0.2	0.3	0.5	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.5	-0.5	-0.7
Asthma	0.2	0.4	0.5	0.5	0.7
Depression (self-reported)	0.2	0.2	0.3	-0.4	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.3	-0.5	-0.5
Arm predicted mass (right)	0.2	1.0	1.2	-1.1	-0.9
Whole body fat-free mass	0.2	1.1	1.3	-1.1	-1.0
Loneliness, isolation	0.2	0.3	0.5	-0.7	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.2	0.4	0.5
Breast cancer (self-reported)	0.2	0.3	0.3	-0.5	-0.5
Medication: Aspirin	0.2	0.2	0.4	0.6	-0.2
Whole body water mass	0.2	1.2	1.4	-1.2	-1.0
Number of self-reported non-cancer illnesses	0.2	0.4	0.6	0.4	0.8
Average weekly champagne plus white wine intake	0.2	0.3	0.4	-0.5	-0.6
Mother’s age at death	0.2	0.2	0.4	-0.7	-0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.2	0.5	0.5
Age started oral contraceptive pill	0.2	0.2	0.3	-0.6	-0.4
Depression (Nagel 2018)	0.1	0.1	0.2	0.2	0.4
Alzheimer’s Disease (in mother)	0.1	0.1	0.1	0.4	0.1
Ulcerative Colitis (UC)	0.1	0.2	0.3	-0.0	-0.6
Breast Cancer	0.1	0.3	0.5	-0.2	-0.7
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	-0.4	-0.4
Neuroticism (2016)	0.1	0.2	0.2	-0.5	-0.3
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.1	0.0	0.4
Blood Red Count	0.1	1.4	1.5	1.2	1.1
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.2	0.1	0.4
Chronotype (morning person)	0.1	0.1	0.3	-0.0	-0.5
Hand grip strength (left)	0.1	0.2	0.4	-0.3	-0.6
Sensitivity / hurt feelings	0.1	0.2	0.3	0.6	0.3
Relative age of first facial hair	0.1	0.2	0.3	-0.2	-0.6
Severe depression (siblings)	0.1	0.1	0.1	0.4	0.3
Leg fat-free mass (left)	0.1	0.4	0.5	-0.7	-0.5
Fed-up feelings	0.1	0.1	0.2	-0.2	-0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	-0.4	0.2
Multivitamins +/- minerals	0.1	0.1	0.3	-0.2	-0.5
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.1	0.4
Body mass index (BMI)	0.1	0.4	0.4	0.6	0.6
Leg predicted mass (left)	0.1	0.4	0.6	-0.8	-0.5
Had other major operations	0.1	0.1	0.1	0.3	0.3
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.1	0.1	0.4
Diabetes (self-reported)	0.1	0.1	0.2	0.5	0.2
Fluid intelligence score	0.1	0.1	0.2	0.5	0.0
Arm fat percentage (right)	0.1	0.5	0.6	0.6	0.8
Hip circumference	0.1	0.6	0.8	0.6	0.9
Pulse rate	0.1	0.2	0.5	0.0	0.7
Mouth/teeth dental problems: Dentures	0.1	0.2	0.2	-0.5	-0.5
Medication: Cholesterol lowering	0.1	0.2	0.3	0.2	0.6
Illnesses of mother	0.1	0.2	0.2	0.3	0.5
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	-0.2	-0.3
Impedance of arm (left)	0.1	0.3	0.4	0.6	0.6
Arm fat mass (right)	0.1	0.3	0.3	0.4	0.6
Standing height	0.1	0.6	0.7	-0.9	-0.7
Exposure to tobacco smoke at home	0.1	0.1	0.2	-0.4	-0.2
Birth weight of first child	0.1	0.3	0.3	-0.6	-0.4
Headache pain in last month	0.1	0.2	0.2	-0.5	-0.5
Birth weight	0.1	0.3	0.3	-0.5	-0.5
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	0.3	0.4
High blood pressure (siblings)	0.1	0.1	0.2	0.3	0.4
Leg fat percentage (right)	0.1	0.4	0.5	0.7	0.5
Arm fat-free mass (right)	0.1	0.6	0.7	-0.9	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.1	-0.4	0.2
Pulse wave peak to peak time	0.1	0.1	0.2	0.3	0.4
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	0.2	0.3
Neck or shoulder pain in last month	0.1	0.1	0.1	-0.4	-0.3
Medication: Seretide 50 evohaler	0.1	0.2	0.3	0.6	0.1
Whole body fat mass	0.1	0.6	0.6	0.7	0.8
Comparative height size at age 10	0.1	0.3	0.3	0.6	0.5
Number of full sisters	0.1	0.1	0.2	-0.4	0.1
Illnesses of siblings: Diabetes	0.1	0.2	0.2	0.4	0.4
Leg fat-free mass (right)	0.1	0.3	0.5	-0.7	-0.4
Arm fat percentage (left)	0.1	0.4	0.5	0.6	0.7
Medication for cholesterol	0.1	0.2	0.4	-0.3	-0.6
Medication: Gliclazide	0.1	0.1	0.1	0.3	0.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.1	0.0	0.4
Leg predicted mass (right)	0.1	0.4	0.5	-0.7	-0.4
Medication: Atorvastatin	0.1	0.1	0.2	-0.2	-0.4
Basal metabolic rate	0.1	0.7	0.9	-0.9	-0.8
Leg fat percentage (left)	0.1	0.3	0.5	0.7	0.5
Arm fat-free mass (left)	0.1	0.4	0.5	-0.7	-0.6
Average weekly beer plus cider intake	0.1	0.2	0.2	-0.3	-0.4
Fractured/broken bones in last 5 years	0.1	0.1	0.2	0.2	0.5
Diastolic blood pressure, automated reading	0.1	0.4	0.4	0.7	0.5
Pack years of smoking	0.1	0.2	0.2	-0.5	-0.4
Impedance of whole body	0.1	0.6	0.8	0.9	0.6
Depressed Affect (Nagel 2018)	0.0	0.1	0.1	0.3	0.4
Neuroticism (Nagel 2018)	0.0	0.1	0.1	-0.2	-0.3
Schizophrenia (2018)	0.0	0.1	0.1	0.1	-0.3
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.1	-0.1
Worry (Nagel 2018)	0.0	0.0	0.0	-0.2	-0.2
Alzheimer’s Disease (in father)	0.0	0.0	0.0	0.2	-0.1
Crohns Disease (2017)	0.0	0.1	0.1	-0.3	0.2
Irritable Bowel Disease (IBD)	0.0	0.1	0.1	-0.2	-0.3
HbA1C	0.0	0.0	0.1	0.0	0.3
Lupus	0.0	0.0	0.0	-0.0	0.0
Schizophrenia (2014)	0.0	0.1	0.1	-0.3	-0.4
Blood Platelet Count	0.0	0.0	0.1	-0.3	-0.2
BMI	0.0	0.0	0.0	-0.1	0.2
Waist Hip Ratio (WHR)	0.0	0.0	0.1	0.1	-0.3
Respiratory disease	0.0	0.1	0.1	0.1	0.3
Tanning	0.0	0.1	0.1	-0.1	-0.4
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.1	-0.1	-0.2
Angina	0.0	0.0	0.0	-0.1	0.1
Vitamin and mineral supplements	0.0	0.0	0.0	-0.2	0.1
Supplements: Zinc	0.0	0.0	0.1	-0.0	0.2
Impedance of leg (right)	0.0	0.1	0.2	0.4	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.0	-0.2	-0.0
Sitting height	0.0	0.0	0.0	0.0	0.2
Impedance of leg (left)	0.0	0.2	0.3	0.6	-0.1
Waist circumference	0.0	0.0	0.0	0.1	0.1
Number of incorrect matches in round	0.0	0.0	0.0	-0.0	0.1
Hearing difficulty/problems with background noise	0.0	0.1	0.1	0.0	0.4
Mouth/teeth dental problems	0.0	0.0	0.0	0.2	-0.0
Allergy	0.0	0.0	0.1	0.3	-0.1
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.0	-0.2	0.2
Medication: Ramipril	0.0	0.0	0.1	0.1	-0.3
Weight	0.0	0.1	0.1	0.2	0.3
Impedance of arm (right)	0.0	0.1	0.1	0.3	0.3
Worrier / anxious feelings	0.0	0.0	0.1	-0.0	-0.2
Pulse wave reflection index	0.0	0.0	0.0	0.1	0.1
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	0.2	0.0
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.0	0.2	-0.1
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.1	-0.0	0.3
Comparative body size at age 10	0.0	0.1	0.3	0.5	-0.1
Wheeze or whistling in the chest in last year	0.0	0.0	0.1	0.1	0.3
Medication for pain relief, constipation, heartburn	0.0	0.0	0.0	0.0	0.0
Angina (self-reported)	0.0	0.0	0.1	0.0	0.2
Migraine (self-reported)	0.0	0.0	0.0	-0.1	-0.0
Leg fat mass (right)	0.0	0.2	0.2	0.4	0.4
Pulse rate, automated reading	0.0	0.1	0.2	-0.2	0.4
Age at last live birth	0.0	0.0	0.0	-0.1	-0.1
Average weekly red wine intake	0.0	0.0	0.1	-0.2	0.0
Mood swings	0.0	0.0	0.0	-0.0	0.1
Mineral and other dietary supplements	0.0	0.0	0.1	0.3	-0.1
Asthma (self-reported)	0.0	0.1	0.1	0.2	0.3
Arm fat mass (left)	0.0	0.2	0.3	0.3	0.5
Miserableness	0.0	0.0	0.1	-0.3	-0.0
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.0	-0.1	-0.1
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	-0.0	-0.0
High cholesterol (Self-reported)	0.0	0.0	0.0	-0.1	0.2
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	-0.1	0.2
Cholesterol lowering medication	0.0	0.0	0.0	0.2	0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	-0.1	0.1
Supplements: Calcium	0.0	0.0	0.0	-0.2	0.2
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	0.1	0.0
Leg fat mass (left)	0.0	0.1	0.2	0.4	0.3
Arm predicted mass (left)	0.0	0.2	0.3	-0.5	-0.4

Hub : Genes

PHC3

Models

Trait associations