TWAS hub - GPR160

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.0780	0.0340	5.5e-03	0.052	NA	-0.002	NA	0.029	1.1e-03	NA	4.1e-01	NA	1.2e-02
2	GTEx	Breast Mammary Tissue	0.1150	0.0570	9.6e-03	0.000	NA	0.001	NA	0.007	3.3e-01	NA	2.7e-01	NA	1.3e-01
3	GTEx	Breast Mammary Tissue (Male)	0.1143	0.0744	6.8e-02	-0.013	NA	0.001	NA	-0.001	8.8e-01	NA	3.0e-01	NA	3.3e-01
4	GTEx	Breast Mammary Tissue (Female)	0.1238	0.0824	7.5e-02	0.044	NA	0.019	NA	0.015	1.8e-02	NA	8.9e-02	NA	1.1e-01
5	GTEx	Esophagus Mucosa	0.2140	0.0520	1.5e-08	0.119	NA	0.062	NA	0.065	2.6e-08	NA	5.3e-05	NA	3.7e-05
6	GTEx	Spleen	0.2090	0.0770	1.0e-03	0.099	NA	0.077	NA	0.097	1.6e-03	NA	5.0e-03	NA	1.8e-03
7	GTEx	Stomach	0.1980	0.0590	2.6e-05	0.113	NA	0.132	NA	0.115	4.6e-06	NA	7.1e-07	NA	3.7e-06
8	GTEx	Testis	0.1580	0.0570	2.9e-04	0.077	NA	0.021	NA	0.051	2.7e-04	NA	3.8e-02	NA	2.6e-03
9	GTEx	Whole Blood	0.1840	0.0390	8.8e-13	0.165	NA	0.175	NA	0.168	5.3e-15	NA	6.7e-16	NA	2.6e-15
10	METSIM	Adipose	0.0720	0.0209	4.2e-11	0.099	0.085	0.099	0.084	0.092	1.5e-14	1.1e-12	1.2e-14	1.3e-12	1.3e-13
11	NTR	Blood	0.0204	0.0081	8.5e-04	0.020	0.006	0.012	0.008	0.017	3.7e-07	5.0e-03	7.9e-05	8.9e-04	2.3e-06
12	YFS	Blood	0.1999	0.0297	0.0e+00	0.197	0.250	0.273	0.256	0.271	2.0e-62	3.4e-81	1.1e-89	4.0e-83	8.5e-89
13	TCGA	Brain Lower Grade Glioma	0.0432	0.0203	3.0e-06	0.057	0.044	0.041	NA	0.044	4.2e-07	8.9e-06	1.9e-05	NA	7.8e-06
14	TCGA	Testicular Germ Cell Tumors	0.1280	0.0610	1.8e-04	0.160	0.121	0.133	NA	0.147	2.8e-06	4.9e-05	2.1e-05	NA	7.0e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	4	5	6	7	8	9	10	11	12	13	14
Prostate Cancer	8.0	11.2	43.8	-1.0	1.6	1.7	4.1	-0.9	-6.6	-0.9	-6.0	-0.5	-6.4	-3.1	-0.6	-0.8
Had menopause	5.5	6.9	11.6	-3.3	-2.8	-1.4	-2.4	-2.8	-2.0	-3.4	-1.9	-3.0	-1.7	-3.1	-3.4	-3.3
Diabetes (mother)	4.5	5.7	12.8	-3.2	-2.7	-0.8	-1.4	-3.6	-2.8	-2.5	-2.9	-1.6	-2.6	-2.8	-2.0	-1.9
Eye problems/disorders: Cataract	4.2	4.9	10.1	-2.9	-0.5	-1.0	-1.6	-3.2	-2.1	-3.1	-2.3	-2.3	-2.1	-2.5	-2.3	-2.3
Eye problems/disorders: None of the above	3.5	4.0	8.2	2.5	-0.2	-0.6	0.7	2.7	1.9	2.9	2.7	1.7	2.4	2.5	2.0	2.1
Chest pain or discomfort	3.1	4.4	8.2	-2.5	-1.2	0.6	-1.5	-2.2	-2.0	-2.5	-1.9	-2.9	-1.5	-2.7	-2.7	-2.7
Reason for reducing amount of alcohol drunk: Health precaution	2.8	3.3	7.3	-2.7	-0.0	-0.5	-1.8	-2.3	-1.2	-2.3	-1.4	-2.2	-1.0	-2.1	-2.3	-2.4
Falls in the last year	2.7	3.6	7.4	-2.5	-1.5	0.3	-0.7	-2.7	-2.2	-2.1	-2.5	-1.8	-2.1	-2.1	-1.8	-1.8
Wears glasses or contact lenses	2.6	3.0	9.1	-2.0	-3.0	-1.2	-1.7	-2.2	-1.0	-2.0	-1.5	-1.9	-1.2	-1.5	-1.8	-1.6
Risk taking	2.6	3.8	6.4	-2.5	-1.1	0.2	-1.7	-2.4	-1.8	-2.5	-2.0	-2.0	-1.6	-2.2	-2.4	-2.5
Myopia	2.6	3.8	6.0	2.3	-1.4	-1.7	0.1	2.2	2.3	2.3	2.0	2.4	1.8	2.4	1.9	2.2
Worry too long after embarrassment	2.4	4.0	8.9	2.2	0.0	0.1	1.2	2.1	3.0	2.2	2.5	2.2	2.5	2.5	2.1	1.9
Illness, injury, bereavement, stress in last 2 years	2.4	3.0	15.7	-1.8	-0.7	-1.0	-4.0	-2.0	1.3	-1.8	1.5	-1.8	1.7	-0.3	-1.5	-1.3
Crohns Disease (2012)	2.3	3.7	7.2	-2.6	-0.1	0.6	-0.8	-2.6	-1.9	-2.4	-1.6	-2.7	-1.4	-2.2	-2.2	-2.4
Medication: Levothyroxine sodium	2.3	4.0	7.9	-2.3	-1.1	-0.7	-1.1	-1.9	-2.1	-2.2	-2.4	-2.4	-2.1	-2.8	-2.4	-2.4
Taking other prescription medications	2.2	3.4	6.6	-2.3	-2.6	-0.4	-1.4	-2.0	-1.2	-2.2	-1.5	-2.5	-1.2	-2.0	-2.1	-2.1
Hypothyroidism (self reported)	2.1	4.7	10.2	-2.7	-1.4	-1.2	-2.7	-2.0	-1.0	-2.7	-0.9	-3.2	-0.4	-2.4	-3.0	-3.1
Bipolar Disorder (2011)	2.0	2.0	5.7	-1.9	-1.0	-0.5	-2.4	-1.9	0.3	-1.8	0.6	-1.7	1.1	-0.7	-1.6	-1.6
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.1	10.0	1.3	0.5	1.4	-0.2	0.9	2.7	1.0	2.8	1.5	3.2	2.7	1.4	1.1
Hypothyroidism/myxoedema (self-reported)	2.0	3.8	7.0	-2.5	-1.0	-1.4	-2.0	-2.1	-1.2	-2.5	-1.4	-2.6	-0.9	-2.4	-2.6	-2.6
Illnesses of father: High blood pressure	2.0	2.5	5.8	1.9	-1.0	0.3	-0.3	1.8	2.4	1.5	2.3	1.3	2.0	2.0	1.3	1.4
Blood Eosinophil Count	1.9	14.9	33.6	-3.8	-0.7	0.5	0.6	-3.3	-5.1	-3.8	-5.5	-4.2	-5.0	-5.8	-4.1	-4.2
Qualifications: College or University degree	1.9	5.8	15.9	2.5	4.0	1.5	1.6	2.2	1.6	2.7	2.1	2.7	1.9	2.7	3.0	2.8
Family relationship satisfaction	1.9	2.3	4.2	-2.0	0.3	0.5	-0.1	-2.0	-1.4	-1.9	-1.9	-1.4	-1.6	-1.9	-1.7	-2.0
Friendships satisfaction	1.9	2.3	9.7	-0.6	2.1	3.1	1.4	-0.7	-1.6	-0.7	-2.3	0.1	-2.2	-1.4	-0.5	-0.7
Number of self-reported non-cancer illnesses	1.9	3.3	6.7	-2.4	-2.6	0.3	-2.6	-2.4	-0.8	-2.1	-0.7	-2.3	-0.4	-1.2	-2.1	-1.9
Number of treatments/medications taken	1.8	3.2	6.9	-2.6	-2.4	-1.0	-2.2	-2.5	-0.9	-2.2	-1.1	-2.2	-0.7	-1.2	-1.8	-1.7
Fed-up feelings	1.8	3.3	5.9	2.3	1.7	1.5	2.0	1.9	0.8	2.0	1.0	2.4	0.6	2.3	2.4	2.4
Birth weight	1.8	3.9	8.1	2.9	0.1	0.3	2.0	2.8	1.1	2.8	1.2	2.2	0.8	2.1	2.7	2.6
Long-standing illness, disability or infirmity	1.8	2.7	7.9	-2.1	-1.6	-1.8	-1.5	-2.8	-1.3	-2.2	-1.8	-1.2	-1.3	-1.4	-1.2	-1.2
Qualifications: CSEs or equivalent	1.7	2.2	9.2	1.7	-0.5	-0.1	3.0	1.2	-0.4	1.6	-0.7	2.2	-1.3	0.8	1.9	1.9
Time employed in main current job	1.7	2.0	11.5	0.3	-3.1	-3.4	-0.3	0.5	1.7	0.6	1.1	0.1	0.8	0.5	0.4	0.5
Age at first live birth	1.7	3.1	5.6	2.0	2.1	0.5	1.2	1.3	1.6	1.8	1.5	2.4	1.5	2.1	2.4	2.4
Ever used hormone-replacement therapy (HRT)	1.6	2.1	4.2	-2.0	-1.1	0.3	-1.5	-2.0	-1.2	-1.9	-1.3	-1.5	-1.2	-1.4	-1.6	-1.6
Medication: Omeprazole	1.6	1.9	6.2	1.0	-2.5	-1.5	-0.0	0.8	1.6	1.0	1.6	0.9	1.8	1.7	1.4	1.3
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	4.2	-1.5	-1.2	0.8	-2.0	-1.6	0.6	-1.8	-0.3	-1.6	-0.3	-1.1	-1.3	-1.3
Noisy workplace	1.5	1.9	3.2	1.7	0.5	0.3	0.4	1.8	0.9	1.6	1.7	1.7	1.4	1.8	1.6	1.7
Mouth/teeth dental problems: Dentures	1.5	2.5	8.6	-1.9	-1.7	-1.7	-2.9	-1.9	-0.6	-1.9	0.1	-2.1	0.3	-0.8	-1.6	-1.5
Loud music exposure frequency	1.5	1.6	4.6	0.2	1.5	2.1	2.1	0.1	-1.7	0.2	-1.8	1.2	-1.8	-0.7	0.5	0.5
Overall health rating	1.5	3.2	8.1	-2.6	-0.9	-0.6	-1.4	-2.8	-1.3	-2.6	-1.8	-1.8	-1.2	-1.9	-1.9	-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	4.5	0.8	-1.8	-1.3	-1.4	0.8	2.1	0.7	2.0	0.7	1.9	1.4	0.7	0.7
Back pain experienced in last month	1.5	2.2	6.7	-1.5	-2.6	-1.8	-1.1	-2.0	-1.2	-1.9	-1.6	-1.0	-1.1	-1.3	-1.0	-1.0
Major Depression (MDD)	1.3	1.6	5.2	-0.8	-0.3	0.6	0.8	-0.6	-1.6	-1.2	-2.3	-0.7	-2.3	-2.0	-1.0	-1.0
Type 2 Diabetes (T2D) (2012)	1.3	1.5	3.9	-1.8	-0.7	-1.0	-1.4	-1.7	-0.6	-1.6	-0.6	-2.0	-0.1	-1.0	-1.3	-1.4
Pain all over the body in last month	1.3	1.4	4.1	0.8	1.2	-0.5	-0.1	0.7	2.0	0.9	1.8	1.2	1.6	1.7	0.9	0.9
Had major operations	1.3	1.5	4.7	-1.7	-0.4	0.4	-1.2	-2.2	-1.5	-1.8	-1.2	-1.0	-1.0	-1.2	-1.0	-1.0
Illnesses of father: Heart disease	1.3	1.8	3.3	-1.1	-1.2	-1.5	-1.0	-0.9	-1.1	-1.2	-1.4	-1.8	-1.5	-1.7	-1.6	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	2.9	-1.7	-1.4	-0.3	-1.4	-1.6	-0.9	-1.5	-0.7	-1.4	-0.7	-1.3	-1.4	-1.4
Osteoporosis (self-reported)	1.3	1.6	5.3	0.9	2.3	1.8	2.0	0.8	-1.2	0.9	-1.2	0.7	-1.4	-0.2	1.1	1.0
Osteoarthritis (self-reported)	1.3	1.7	4.5	-0.9	2.0	0.1	0.2	-0.9	-1.8	-1.2	-2.1	-0.2	-2.1	-1.5	-1.1	-1.0
Schizophrenia vs Biploar Disorder	1.2	1.6	4.6	-1.2	-1.2	-2.0	-2.1	-1.0	0.5	-1.6	0.2	-1.2	0.5	-0.7	-1.6	-1.6
Ulcerative Colitis	1.2	1.7	6.4	1.7	0.9	-0.4	2.5	1.7	0.3	1.5	0.2	1.8	-0.0	1.0	1.6	1.4
Average weekly fortified wine intake	1.2	1.5	4.8	0.6	0.1	1.6	2.1	0.3	-1.3	0.8	-1.5	1.2	-2.2	-0.2	1.1	1.0
High blood pressure	1.2	3.4	8.2	-2.4	-2.9	-2.1	-1.1	-2.4	-1.5	-2.3	-1.5	-1.3	-1.4	-1.5	-1.9	-1.9
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	2.6	1.2	1.2	1.4	1.0	1.0	0.6	1.5	0.8	1.4	0.6	1.4	1.6	1.5
Hayfever/allergic rhinitis (self-reported)	1.2	1.5	3.8	-1.7	-0.2	-0.1	-1.9	-1.6	-0.2	-1.7	-0.2	-1.9	0.2	-1.0	-1.5	-1.5
Neuroticism score	1.2	2.5	4.8	1.9	0.1	1.2	0.9	2.0	2.2	1.7	2.2	1.3	2.0	2.1	1.3	1.2
Exposure to tobacco smoke outside home	1.2	1.6	5.1	-0.8	-2.3	-0.8	0.5	-0.6	-1.3	-0.8	-1.7	-1.4	-1.8	-1.9	-1.2	-1.0
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	3.7	-1.2	-0.5	-1.1	-0.4	-0.5	-1.1	-0.8	-1.2	-1.3	-1.0	-1.8	-1.9	-1.9
Supplements: Vitamin C	1.2	1.4	2.8	1.6	-0.6	-0.6	0.7	1.7	1.1	1.2	1.2	1.4	1.2	1.6	1.3	1.4
Guilty feelings	1.2	1.9	6.9	1.2	-0.6	-0.3	-0.1	1.4	1.7	0.9	2.5	0.9	2.6	1.8	0.8	0.7
Unable to work because of sickness or disability	1.2	1.6	3.2	-1.7	0.8	0.0	-1.2	-1.8	-0.8	-1.8	-1.2	-1.7	-1.0	-1.3	-1.5	-1.3
Heart disease (siblings)	1.2	1.5	5.2	0.8	1.1	0.9	2.1	1.0	-0.8	1.0	-1.9	0.9	-2.3	-0.8	0.2	0.2
Medication: Paracetamol	1.1	1.7	3.2	1.2	0.7	0.5	1.0	1.0	1.8	1.4	1.5	1.4	1.3	1.7	1.8	1.8
Comparative body size at age 10	1.1	3.0	8.5	1.9	1.9	2.9	2.2	1.5	-0.1	1.9	-0.1	2.0	-0.3	1.1	2.3	2.2
Mouth/teeth dental problems: Loose teeth	1.1	1.3	4.2	-0.7	-2.0	-1.7	-0.2	-0.1	-1.0	-0.7	-0.8	-1.2	-1.0	-1.4	-1.4	-1.3
Commuting to job workplace: Car/motor vehicle	1.1	1.3	4.1	1.2	0.8	-0.0	2.0	1.4	-0.7	1.5	-0.4	1.6	-0.6	0.4	1.3	1.4
Hypertension (Self-reported)	1.1	3.1	9.4	-2.2	-3.1	-2.3	-1.4	-2.2	-1.1	-2.1	-1.1	-1.2	-0.9	-1.2	-1.8	-1.8
Smoking status: Current	1.1	1.7	4.9	-0.7	-1.1	-2.2	0.9	-0.2	-1.4	-0.5	-2.0	-0.8	-2.2	-1.6	-1.1	-1.1
Crohns Disease (2017)	1.0	2.2	5.5	-2.3	0.7	0.7	-0.9	-2.4	-0.8	-1.9	-0.3	-2.3	0.0	-1.4	-1.7	-1.9
Heel T-Score	1.0	7.9	21.1	3.1	-0.9	-0.9	-0.8	3.1	4.6	2.7	4.4	1.2	4.1	3.4	2.4	2.4
Smoking Status	1.0	2.3	3.9	-1.7	-1.9	-1.4	-1.2	-1.6	-0.8	-2.0	-1.3	-1.7	-1.0	-1.5	-1.9	-2.0
Systolic blood pressure, automated reading	1.0	2.8	5.1	-2.1	-2.2	-0.8	-0.8	-1.6	-1.7	-1.8	-1.3	-1.7	-1.4	-1.8	-2.2	-2.3
Hand grip strength (right)	1.0	2.6	4.9	2.2	1.3	0.2	1.2	2.0	1.5	2.0	1.3	1.9	1.2	1.9	2.1	1.9
Multivitamins +/- minerals	1.0	1.2	3.5	1.2	0.0	0.6	1.3	0.7	-0.0	1.1	0.6	1.7	0.6	1.4	1.9	1.7
Age at last live birth	1.0	1.4	4.0	1.4	2.0	1.1	1.3	0.9	0.3	1.1	0.5	1.6	0.6	1.4	1.5	1.4
Smoking status: Previous	1.0	1.5	3.4	-1.5	-0.8	0.6	-1.1	-1.4	-0.9	-1.8	-0.9	-1.4	-0.6	-1.1	-1.6	-1.7
Miserableness	1.0	1.8	3.3	1.7	1.1	1.7	1.8	1.6	0.3	1.6	0.5	1.6	0.1	1.3	1.6	1.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	5.6	1.1	-2.4	-1.7	0.9	1.0	0.7	1.0	0.4	0.8	0.5	1.0	1.2	1.1
Ovarian Cancer	0.9	1.1	3.2	0.7	-1.1	-1.6	-1.2	0.4	1.2	0.6	1.4	0.6	1.8	1.3	0.7	0.8
Average weekly spirits intake	0.9	1.1	6.2	-0.1	1.5	2.5	1.0	-0.1	-1.5	0.2	-1.1	0.2	-1.3	-0.7	0.1	0.2
Medication for hormone replacement therapy	0.9	1.0	3.3	-1.1	0.0	-0.9	-1.8	-0.9	1.5	-1.0	1.0	-0.8	1.3	-0.1	-0.8	-0.7
Current tobacco smoking	0.9	1.4	4.5	-0.5	-0.8	-1.8	0.9	-0.1	-1.2	-0.4	-1.9	-0.7	-2.1	-1.5	-1.0	-1.0
Serious illness, injury or assault to yourself	0.9	1.1	4.7	-0.7	-0.2	0.0	0.5	-1.4	-1.6	-0.6	-2.0	0.2	-2.2	-0.7	0.2	0.2
Past tobacco smoking	0.9	1.6	3.5	1.6	0.9	-0.0	1.1	1.5	0.8	1.9	1.0	1.4	0.7	1.3	1.8	1.9
Financial difficulties in last 2 years	0.9	1.2	3.0	-0.3	-0.8	1.5	1.3	0.1	-1.4	-0.4	-1.7	-0.7	-1.7	-1.4	-0.7	-0.7
Happiness	0.9	1.1	2.9	1.0	1.2	1.5	1.7	0.9	-0.4	0.9	-0.8	1.3	-1.0	0.3	1.0	0.8
Number of children fathered	0.9	1.0	3.3	-1.0	-0.7	-1.8	-1.8	-0.8	0.5	-1.1	0.3	-0.6	0.5	-0.5	-1.2	-1.1
Emphysema/chronic bronchitis	0.9	1.0	3.1	0.3	0.3	1.4	1.5	0.0	-1.5	0.4	-1.6	0.4	-1.8	-0.4	0.6	0.7
Commuting to job workplace: Walk	0.9	1.0	3.6	0.7	-0.9	0.7	-0.4	0.5	1.3	0.6	1.8	0.5	1.9	1.4	0.8	0.6
Alcohol drinker status: Never	0.9	1.1	3.3	-1.6	0.6	-0.0	-0.5	-1.8	-1.6	-1.2	-1.1	-1.0	-0.8	-0.9	-0.9	-1.0
Vascular/heart problems diagnosed by doctor	0.9	2.4	6.2	2.0	2.5	2.0	1.0	2.1	1.5	1.8	1.1	0.8	1.0	1.0	1.4	1.4
Bipolar Disorder or Schizophrenia	0.8	1.9	9.3	-1.4	-1.9	0.3	-3.0	-2.0	0.7	-1.5	1.1	-0.8	1.5	0.4	-0.7	-0.6
Schizophrenia (2018)	0.8	1.6	7.6	-1.4	-1.8	-0.5	-2.8	-2.2	0.4	-1.7	0.3	-0.6	0.8	0.1	-0.7	-0.6
Schizophrenia (2014)	0.8	1.7	7.1	-1.5	-1.5	-1.3	-2.7	-2.3	0.4	-1.8	0.3	-0.6	0.7	0.1	-0.7	-0.6
Cardiovascular Disease	0.8	2.6	8.4	-1.9	-2.9	-1.9	-0.9	-2.4	-1.3	-1.9	-1.3	-0.8	-1.2	-1.2	-1.3	-1.3
Relative age voice broke	0.8	1.2	2.2	1.4	0.2	1.0	1.0	1.4	1.5	1.5	1.0	1.2	0.5	1.2	1.2	1.3
Medication: Atenolol	0.8	1.0	3.5	-1.0	-0.9	-0.3	-0.1	-1.2	-1.9	-1.1	-1.5	-0.2	-1.5	-0.9	-0.6	-0.7
Mouth/teeth dental problems	0.8	1.2	3.5	1.4	1.5	1.2	1.9	1.6	0.6	1.4	0.1	1.1	-0.2	0.4	0.9	0.7
Hair/balding pattern: Pattern 3	0.8	1.2	3.6	-1.4	-0.4	-0.9	-1.1	-1.9	-0.4	-1.5	-0.9	-1.1	-0.5	-1.0	-1.1	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	4.0	1.2	0.6	0.7	2.0	1.6	-0.2	1.4	-0.4	0.5	-0.7	0.1	0.8	0.6
Length of working week for main job	0.8	0.9	4.1	-0.6	-2.0	-0.8	-1.0	-0.1	-0.8	-0.4	-0.2	-1.2	-0.3	-1.2	-1.2	-0.9
Peak expiratory flow (PEF)	0.8	1.9	3.4	1.8	1.6	0.1	0.4	1.5	1.2	1.5	1.5	1.6	1.4	1.7	1.5	1.5
Health satisfaction	0.8	1.0	2.2	-1.0	-0.5	-1.0	-0.4	-0.8	-0.5	-1.0	-1.1	-1.3	-0.9	-1.3	-1.4	-1.5
Medication: Allopurinol	0.8	1.1	5.5	-0.8	0.4	-0.2	-2.3	-0.9	1.3	-1.1	1.2	-0.9	1.3	0.6	-0.5	-0.4
Eye problems/disorders: Glaucoma	0.8	1.0	5.1	-0.7	-0.9	-0.3	-2.3	-0.6	1.1	-1.1	0.8	-0.7	0.9	0.2	-1.0	-0.9
Ever smoked	0.8	1.3	2.8	-1.5	-0.7	-0.2	-0.9	-1.5	-0.7	-1.7	-1.1	-1.2	-0.7	-1.2	-1.5	-1.6
Fractured/broken bones in last 5 years	0.8	1.0	2.5	-1.6	0.8	-0.3	-0.7	-1.4	-0.8	-1.2	-0.6	-0.7	-0.5	-1.1	-1.3	-1.4
Cholesterol lowering medication	0.8	1.2	8.0	-1.1	-2.8	-1.5	-1.4	-1.1	0.4	-1.0	0.2	-0.6	0.2	-0.3	-0.7	-0.6
Alcohol drinker status: Previous	0.8	0.9	3.8	-0.4	-1.9	-1.8	-0.3	-0.1	-1.1	-0.6	-0.9	-0.1	-1.0	-0.9	-0.7	-0.6
Coronary Artery Disease (CAD)	0.7	0.9	2.7	-0.2	-0.1	1.1	-0.8	-0.4	1.3	0.2	1.4	0.9	1.6	1.4	0.9	0.7
Mean Putamen Volume	0.7	0.8	3.0	0.8	0.5	0.4	-0.6	0.6	1.7	0.6	1.3	0.4	1.2	1.3	0.7	0.7
HDL Cholesterol	0.7	1.1	3.5	1.1	0.2	-0.9	-0.6	0.9	1.9	1.0	1.9	0.5	1.5	1.2	0.7	0.7
Medication: Co-codamol	0.7	0.8	1.7	-1.2	-0.5	0.3	-0.6	-1.3	-1.0	-1.1	-1.0	-0.7	-1.1	-0.9	-1.0	-0.9
Nervous feelings	0.7	1.3	5.0	0.1	2.2	2.0	-0.4	0.0	1.2	0.2	1.6	0.1	1.8	1.1	0.1	0.0
Medication: Ramipril	0.7	0.9	2.6	-1.5	-0.8	-0.8	-1.5	-1.6	-0.5	-1.4	-0.2	-0.7	0.2	-0.3	-0.9	-0.8
Depression (self-reported)	0.7	0.8	2.2	-1.1	0.4	1.4	-0.8	-0.6	-0.3	-0.8	-0.1	-1.0	-0.2	-1.0	-1.5	-1.4
Medication: Lansoprazole	0.7	0.8	3.0	-0.6	-1.7	-0.4	-0.4	-0.3	-1.0	-0.7	-1.1	-0.8	-1.3	-0.9	-1.0	-1.0
Prospective memory result	0.7	0.9	2.2	1.2	-0.3	-0.5	1.1	1.5	1.1	1.3	0.7	1.3	0.3	0.8	0.8	0.7
Birth weight of first child	0.7	1.3	3.1	1.6	1.8	0.5	0.6	1.7	0.8	1.5	1.0	0.9	0.7	1.3	1.0	1.0
Pulse wave peak to peak time	0.7	0.8	2.0	-1.1	0.1	-0.5	-1.0	-1.2	-0.6	-1.4	-0.6	-0.8	-0.3	-0.8	-1.1	-1.2
Neck or shoulder pain in last month	0.7	1.0	9.1	-0.6	-3.0	-1.2	-0.7	-0.7	0.8	-0.4	-0.1	-1.0	0.1	-0.2	-0.5	-0.4
Medication: Blood pressure	0.7	1.2	3.8	-1.2	-0.7	-1.4	0.0	-1.2	-1.9	-1.1	-1.6	-0.4	-1.4	-1.1	-0.8	-0.8
Alcohol intake frequency.	0.7	1.5	6.8	-0.8	-1.2	-0.5	1.2	-0.7	-2.6	-0.3	-2.1	0.2	-2.0	-1.2	-0.3	-0.4
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.5	0.4	1.5	1.6	-0.1	0.2	1.1	0.6	1.1	0.9	1.0	1.1	0.5	0.4
Diabetes diagnosed by doctor	0.7	1.1	2.5	-0.9	-1.6	-1.6	-0.2	-0.9	-1.6	-0.6	-1.3	-0.6	-1.1	-1.0	-0.8	-0.8
Medication for cholesterol	0.7	1.1	5.6	1.1	2.4	1.5	1.4	1.4	-0.2	1.3	0.2	0.6	0.1	0.3	0.5	0.4
Financial situation satisfaction	0.7	0.8	2.0	-0.2	-0.9	1.3	0.9	0.1	-1.2	-0.4	-1.3	-0.8	-1.4	-1.2	-0.6	-0.7
High cholesterol (Self-reported)	0.7	1.2	4.5	-1.9	-0.7	0.1	-1.7	-2.1	-0.4	-1.4	-0.2	-0.9	0.0	-0.6	-0.8	-0.9
Pain experienced in last month	0.7	1.2	2.0	-1.1	0.4	1.4	-0.4	-0.9	-1.4	-1.3	-1.1	-1.2	-1.1	-1.3	-1.2	-1.3
Fasting Glucose	0.6	0.8	3.3	0.6	-1.4	-1.8	-0.6	0.6	0.5	0.8	1.1	0.3	0.9	0.9	0.5	0.6
LDL Cholesterol	0.6	0.9	2.5	-0.7	-0.5	-0.2	0.2	-0.2	-1.5	-0.4	-1.2	-0.9	-1.2	-1.6	-1.3	-1.3
Neuroticism	0.6	1.5	4.9	1.1	0.3	2.2	0.9	1.2	1.7	1.0	1.5	0.8	1.4	1.7	1.0	0.9
Ever had hysterectomy (womb removed)	0.6	0.7	2.4	-0.9	-1.5	-0.8	-1.5	-1.4	0.2	-1.0	-0.1	-0.8	0.1	-0.1	-0.6	-0.3
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.5	0.8	0.3	0.0	0.4	0.0	1.0	0.8	0.1	1.4	-0.0	1.3	1.3	1.6
High blood pressure (mother)	0.6	0.8	1.8	-1.1	-0.8	0.4	-0.6	-1.4	-1.0	-1.0	-0.9	-0.6	-1.1	-1.0	-1.0	-0.8
Had other major operations	0.6	0.7	5.6	0.7	-2.4	-0.4	0.6	0.7	-0.2	0.7	-0.2	0.2	-0.4	0.4	1.0	1.1
Exposure to tobacco smoke at home	0.6	0.6	2.6	-0.9	-0.4	-0.5	-1.6	-1.1	-0.5	-0.9	-0.0	-0.9	0.2	-0.5	-1.0	-0.9
Hair/balding pattern: Pattern 4	0.6	1.4	3.1	1.5	0.1	-1.4	0.8	1.8	1.3	1.6	1.6	0.8	1.3	1.1	1.0	0.9
Blood clot in the leg (DVT)	0.6	0.8	2.3	-0.6	-1.5	-1.1	-0.5	-1.1	-1.2	-1.0	-1.2	-0.6	-1.0	-0.5	0.0	0.1
Glaucoma (self-reported)	0.6	0.7	2.6	-0.1	-1.0	-0.3	-1.6	-0.0	1.6	-0.4	1.2	0.1	1.4	0.9	-0.2	-0.2
Knee pain experienced in last month	0.6	0.9	1.9	-1.0	-0.5	-0.7	-0.1	-1.0	-0.9	-1.1	-1.2	-0.8	-0.8	-1.3	-1.4	-1.3
Illnesses of siblings: Diabetes	0.6	0.8	2.0	0.8	0.1	-0.1	1.4	0.7	0.1	1.1	0.2	1.4	-0.0	0.9	1.4	1.3
Ever had bowel cancer screening	0.6	0.7	3.9	-0.0	-1.6	-2.0	-1.0	0.1	0.8	0.1	0.8	-0.4	0.7	0.5	-0.1	0.2
Qualifications: nursing, teaching	0.6	1.0	2.2	0.9	0.1	-0.1	0.4	0.4	0.9	0.9	1.0	1.5	1.1	1.5	1.5	1.3
Ever taken oral contraceptive pill	0.6	0.7	1.6	-0.6	-0.9	-0.1	-0.2	-0.9	-0.9	-0.8	-1.0	-1.3	-0.9	-0.9	-0.8	-0.9
Number of operations (self-reported)	0.6	0.9	2.7	-0.7	-1.3	-0.8	-0.6	-1.0	-1.4	-0.7	-1.6	-0.5	-1.6	-0.8	-0.3	-0.1
Alzheimer’s Disease (in mother)	0.5	0.6	1.5	-0.9	0.3	-0.3	-0.6	-0.6	-0.7	-1.0	-0.6	-1.2	-0.5	-1.0	-1.0	-0.9
Ulcerative Colitis (UC)	0.5	0.9	3.6	0.7	1.9	-0.3	1.0	0.7	1.2	0.7	0.9	1.2	1.0	0.9	0.8	0.6
Breast Cancer	0.5	1.2	3.1	1.1	-0.7	1.6	0.3	0.6	1.2	1.4	0.6	0.8	0.6	1.5	1.6	1.8
HbA1C	0.5	0.6	3.4	-0.4	-1.8	-1.2	-1.2	-1.0	-0.1	-0.3	0.1	-0.2	0.5	0.5	0.2	0.3
Systolic Blood Pressure	0.5	2.5	8.6	-1.6	-2.9	-1.1	-0.7	-1.8	-1.9	-1.7	-1.5	-1.0	-1.6	-1.4	-1.4	-1.4
Hand grip strength (left)	0.5	1.3	2.7	1.6	0.9	-0.0	0.8	1.6	0.9	1.6	0.9	1.4	0.8	1.3	1.2	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	4.2	1.0	-0.5	-1.4	-0.6	1.4	2.1	0.9	1.5	-0.3	1.4	0.6	0.4	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	3.4	0.8	-0.9	-1.7	-0.8	0.9	1.9	0.9	1.7	-0.2	1.6	1.0	0.7	0.6
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	3.5	-0.9	0.3	1.9	-0.5	-0.7	-0.9	-0.7	-0.4	-0.6	-0.4	-0.5	-0.8	-0.8
Father’s age at death	0.5	0.7	3.5	-0.5	-1.9	-1.5	-1.1	-0.6	0.1	-0.3	0.8	-0.3	0.8	0.2	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	8.1	0.7	2.8	-0.1	-0.9	0.1	1.2	0.4	1.5	1.8	1.5	1.5	0.9	0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.0	3.5	1.0	1.9	0.8	1.1	1.1	0.6	1.1	0.8	1.1	0.7	0.8	1.1	0.8
Pulse wave Arterial Stiffness index	0.5	0.5	1.4	0.9	-0.2	0.3	0.9	0.9	0.6	1.2	0.5	0.6	0.2	0.6	0.9	1.1
Tense / ‘highly strung’	0.5	0.8	2.7	-0.9	-0.6	0.5	-1.6	-1.0	0.7	-0.8	1.2	-0.7	1.6	0.4	-0.7	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.5	-1.0	0.1	0.3	0.7	-0.9	-1.1	-0.9	-1.2	-0.6	-1.2	-0.9	-0.7	-1.0
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.6	1.1	0.2	1.0	0.4	1.2	1.6	0.8	1.3	0.3	1.0	0.8	0.5	0.5
Gout (self-reported)	0.5	0.7	2.0	0.2	1.2	-0.6	-1.0	0.2	1.3	0.1	1.4	0.0	1.4	1.1	0.3	0.3
Number of full brothers	0.5	0.7	2.0	1.0	-0.0	0.6	1.4	0.9	0.0	1.1	-0.2	1.1	-0.7	0.3	1.0	1.0
Mean time to correctly identify matches	0.5	0.9	4.5	-1.1	-2.1	0.6	-1.2	-1.1	0.8	-0.7	0.7	-0.9	0.8	-0.2	-0.9	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.7	1.2	0.1	0.8	0.5	1.6	0.8	1.1	0.6	0.5	0.5	0.1	0.4	0.4
Suffer from ‘nerves’	0.5	0.8	3.6	-0.1	0.4	1.6	-0.1	-0.1	1.3	0.1	1.7	-0.4	1.9	0.8	0.0	-0.1
Average weekly red wine intake	0.5	0.7	2.0	0.9	1.3	0.1	1.1	0.5	-0.1	0.8	0.0	1.4	-0.0	0.5	1.2	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.4	0.4	-0.2	1.5	1.0	0.2	-0.2	0.4	-0.0	1.4	0.2	0.7	0.9	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	6.2	0.2	2.5	0.0	-1.3	-0.2	1.0	0.0	1.4	0.9	1.4	0.8	0.3	0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.1	0.9	1.0	-0.7	1.0	0.8	1.0	0.8	0.3	0.7	0.2	0.8	0.9	0.8
Medication: Paracetamol	0.5	0.7	2.0	0.7	0.5	1.0	0.8	0.7	1.4	0.8	0.9	0.7	0.7	0.9	0.9	0.9
Irritability	0.5	0.8	1.7	0.9	0.4	0.7	0.8	0.7	1.0	1.0	1.3	0.9	1.1	1.3	1.0	0.9
Supplements: Calcium	0.5	0.5	1.4	-0.9	-1.1	-0.8	-0.4	-1.2	0.0	-1.1	-0.4	-0.7	-0.1	-0.7	-0.5	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.6	-0.6	-1.2	-0.7	-0.3	-0.9	-1.3	-0.8	-1.1	-0.5	-1.1	-0.5	-0.0	0.1
Bipolar Disorder (2018)	0.4	0.6	2.2	-0.5	-0.7	1.0	-1.4	-0.4	0.6	-0.4	1.3	-0.5	1.5	0.5	-0.2	-0.3
Reaction Time	0.4	0.8	3.1	-1.0	-1.8	0.6	-0.9	-1.4	0.8	-0.7	0.6	-1.0	0.7	-0.2	-0.6	-0.6
Primary Biliary Cirrhosis	0.4	0.5	3.4	-0.0	1.9	1.1	0.7	0.1	-0.9	-0.1	-0.8	-0.2	-0.8	-0.5	-0.2	-0.1
Blood White Count	0.4	3.2	5.2	-2.2	1.8	0.5	-0.4	-2.3	-1.7	-2.2	-1.9	-1.6	-1.6	-2.3	-2.1	-2.2
Lung FVC	0.4	2.0	7.3	-0.7	0.2	-2.6	-2.7	-1.0	1.5	-0.5	2.0	-0.1	2.1	0.7	-0.7	-0.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	1.8	-0.5	-0.4	-0.9	1.0	-0.7	-1.2	-0.1	-1.3	0.4	-1.3	-0.3	0.3	0.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.6	0.3	-0.0	1.6	1.3	0.2	-0.3	0.3	-0.6	0.3	-0.5	0.1	0.4	0.3
Supplements: Zinc	0.4	0.4	1.0	0.8	0.7	-1.0	0.2	0.6	0.7	0.5	0.2	0.7	0.2	0.8	0.9	1.0
Maternal smoking around birth	0.4	0.6	1.4	-1.0	0.9	0.0	-0.3	-1.1	0.1	-0.8	-0.8	-0.5	-0.8	-1.2	-0.9	-0.9
Hayfever, allergic rhinitis or eczema	0.4	0.9	4.3	-0.0	-0.1	0.5	-1.2	0.0	1.9	-0.1	1.8	-0.1	2.1	0.8	-0.1	-0.2
Supplements: Glucosamine	0.4	0.6	6.3	-0.0	2.5	0.3	0.1	0.1	0.8	0.2	0.5	0.3	0.4	0.4	0.2	0.1
Hearing difficulty/problems with background noise	0.4	0.6	3.6	-0.6	-1.9	-1.6	-0.5	-0.5	0.0	-0.4	-0.2	-0.7	-0.2	-0.4	-0.5	-0.4
Heart attack	0.4	0.5	1.1	-0.8	-0.5	-0.8	-0.5	-0.9	-1.0	-0.7	-1.1	-0.5	-0.8	-0.4	-0.4	-0.3
Diabetes (self-reported)	0.4	0.5	2.1	-0.9	-1.2	-1.5	-0.6	-0.9	-0.8	-0.5	-0.5	-0.4	-0.2	-0.4	-0.6	-0.5
Illnesses of siblings	0.4	0.5	3.0	-0.4	0.4	-0.3	-0.9	0.0	0.8	-0.4	1.3	-0.5	1.7	0.3	-0.3	-0.6
Number of live births	0.4	0.6	2.0	1.0	-0.7	1.4	1.1	1.3	-0.7	0.8	-0.3	0.4	-0.4	0.1	0.4	0.4
Asthma	0.4	0.8	1.8	-1.0	-0.7	1.0	-0.8	-0.7	-0.2	-1.1	-0.6	-1.1	-0.5	-1.1	-1.3	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	4.3	0.0	2.1	-0.6	-1.3	-0.7	1.1	-0.0	1.6	1.3	1.6	1.3	0.5	0.5
Medication: Amlodipine	0.4	0.5	1.8	0.8	-0.0	-0.3	0.5	0.5	-0.3	0.8	-0.2	1.4	-0.2	0.8	1.0	1.2
Wheeze or whistling in the chest in last year	0.4	0.6	5.5	-0.2	-2.4	-1.5	-0.2	-0.1	0.3	0.0	-0.1	-0.8	-0.0	-0.5	-0.5	-0.3
Angina (self-reported)	0.4	0.5	1.1	0.7	1.0	0.8	0.1	0.8	-0.1	0.9	0.3	0.8	0.3	0.8	0.8	0.8
Migraine (self-reported)	0.4	0.5	3.0	0.7	0.4	0.6	1.7	0.7	0.1	1.0	0.0	0.8	-0.2	0.3	0.7	0.7
Comparative height size at age 10	0.4	2.1	5.5	-2.0	0.1	-1.1	-2.0	-2.3	-0.7	-2.3	-1.0	-1.3	-0.5	-1.2	-1.4	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.9	0.5	1.3	0.9	0.2	0.1	1.4	0.4	0.9	0.8	1.0	1.4	1.1	0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	3.3	-0.5	-0.1	0.2	-1.8	-0.8	0.5	-0.7	0.9	-0.7	1.4	0.3	-0.4	-0.2
Medication: Aspirin	0.4	0.5	1.2	0.6	-0.7	0.2	-0.1	0.6	0.9	0.8	0.3	1.1	0.2	0.9	0.8	1.0
Illnesses of father: None of the above (group 1)	0.4	0.5	3.1	0.1	1.8	0.1	0.6	-0.3	0.5	0.3	-0.0	0.9	0.1	0.5	1.0	0.9
Commuting to job workplace: Public transport	0.4	0.4	1.9	-0.1	1.4	1.0	0.1	-0.3	-0.9	-0.5	-0.7	-0.5	-0.9	-0.5	-0.4	-0.4
Medication: Blood pressure	0.4	0.8	4.2	-0.7	-2.1	-1.5	-0.8	-1.4	-0.5	-0.9	-0.5	0.1	-0.5	0.2	-0.1	0.1
Medication: Lisinopril	0.4	0.5	1.6	-0.2	-0.4	-1.0	0.9	-0.3	-1.1	-0.6	-1.2	0.2	-1.3	-0.8	-0.1	-0.2
Medication: Atorvastatin	0.4	0.4	0.9	0.7	-0.2	-0.8	-0.5	0.5	0.5	0.6	0.7	0.7	0.8	0.8	0.9	1.0
Diastolic blood pressure, automated reading	0.4	1.2	3.9	-1.1	-2.0	1.1	-0.3	-1.0	-1.0	-1.1	-0.7	-0.8	-0.8	-1.1	-1.4	-1.4
Commuting to job workplace: Cycle	0.4	0.5	1.7	0.2	-0.5	-0.5	-1.3	-0.5	1.1	-0.6	0.8	-0.1	1.3	0.6	0.2	0.2
Depressed Affect (Nagel 2018)	0.3	0.7	5.3	0.6	0.9	2.3	1.0	0.8	0.2	0.5	-0.0	0.2	-0.4	0.6	0.7	0.7
Lupus	0.3	0.4	1.2	-1.1	0.8	-0.5	-0.5	-1.1	-0.2	-0.9	-0.0	-0.5	0.1	-0.3	-0.7	-0.7
Rheumatoid Arthritis	0.3	0.4	1.3	0.7	-0.1	-0.9	1.2	1.1	-1.0	0.8	-0.4	0.1	-0.6	-0.2	0.1	0.0
Triglycerides	0.3	0.5	1.4	0.7	-0.4	0.8	1.2	0.8	-0.5	0.7	-0.7	1.0	-0.7	0.3	0.7	0.8
Blood Platelet Count	0.3	3.2	8.8	1.9	3.0	1.5	2.3	1.6	0.5	1.8	0.5	2.7	0.1	1.6	2.1	2.1
Hearing difficulty/problems: Yes	0.3	0.5	3.0	-0.8	-0.9	-1.7	-0.2	-0.4	-0.8	-0.2	-0.3	-0.8	-0.3	-0.6	-0.6	-0.6
Angina	0.3	0.4	1.4	0.6	1.2	0.7	-0.2	0.7	-0.1	0.7	0.4	0.6	0.4	0.7	0.6	0.7
Sitting height	0.3	2.1	6.2	-1.8	-0.0	-0.6	-2.5	-2.5	-0.5	-2.1	-0.6	-2.0	0.1	-1.0	-1.3	-1.4
Waist circumference	0.3	0.9	5.0	0.9	-2.2	-0.9	0.9	1.0	0.7	1.0	0.4	1.1	0.2	0.8	0.7	0.8
Alcohol usually taken with meals	0.3	0.4	1.0	0.7	0.7	0.7	0.2	0.4	0.4	0.7	0.5	1.0	0.1	0.6	0.8	1.0
Hair/balding pattern: Pattern 2	0.3	0.4	2.4	0.9	-0.4	-0.2	0.3	1.5	0.6	1.0	0.6	0.1	0.2	0.4	0.2	0.2
Forced vital capacity (FVC)	0.3	1.0	4.4	0.4	2.1	-0.3	-0.8	-0.0	1.0	0.3	1.2	1.4	1.2	1.3	0.7	0.5
Fluid intelligence score	0.3	0.7	1.5	1.1	0.3	-0.7	1.0	1.0	-0.2	1.1	-0.0	1.2	-0.0	0.6	1.2	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	1.1	0.7	-0.1	0.8	0.4	0.8	1.0	0.9	1.1	0.4	1.1	0.9	0.7	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.4	-0.1	0.8	-1.0	0.3	-0.1	-0.2	-0.5	-0.9	-0.2	-1.2	-0.7	-0.2	-0.1
Breastfed as a baby	0.3	0.4	1.4	0.9	-0.6	-0.2	-0.2	1.2	0.3	0.9	0.6	0.6	0.5	0.8	0.5	0.7
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.0	-1.0	-0.6	-0.7	-0.6	-0.9	0.4	-0.7	-0.2	-0.5	0.2	-0.4	-0.6	-0.7
Forced vital capacity (FVC), Best measure	0.3	1.2	2.8	-0.2	1.6	-0.9	-1.4	-0.9	1.4	-0.1	1.6	1.1	1.7	1.2	0.4	0.3
Shortness of breath walking on level ground	0.3	0.4	1.6	0.2	0.4	0.5	-1.3	0.2	1.0	0.1	1.0	-0.5	1.0	0.7	0.1	0.3
Medication for pain relief, constipation, heartburn	0.3	0.5	1.3	-0.3	1.2	0.9	-0.3	-0.0	-1.1	-0.5	-0.4	-0.7	-0.2	-0.9	-1.1	-1.0
Pulse rate, automated reading	0.3	0.9	4.2	-1.4	-0.1	0.4	-1.3	-2.1	-0.2	-1.5	-0.2	-0.7	-0.1	-0.6	-0.7	-0.5
Asthma (self-reported)	0.3	0.7	1.7	-0.9	-0.7	1.3	-1.1	-0.7	0.1	-1.0	-0.2	-0.9	-0.1	-0.7	-1.2	-1.0
Mother’s age at death	0.3	0.4	2.5	0.1	-1.6	-0.6	-1.3	0.0	-0.3	0.1	0.6	0.0	0.7	0.3	0.3	0.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.8	0.7	-0.7	-0.5	0.4	0.6	0.8	0.9	0.4	-0.0	0.4	0.6	0.6	0.6
Age started oral contraceptive pill	0.3	0.3	1.1	0.7	-0.9	-1.0	-0.1	0.7	-0.3	0.7	0.7	0.3	0.4	0.3	0.2	0.3
Neuroticism (Nagel 2018)	0.2	0.6	4.3	0.2	1.1	2.1	0.9	0.4	0.5	0.1	0.5	0.1	0.4	0.6	0.4	0.2
Worry (Nagel 2018)	0.2	0.5	1.1	-1.1	1.0	1.0	0.1	-1.0	-0.1	-0.9	0.0	-0.9	0.1	-0.1	-0.5	-0.7
Alzheimer’s Disease (in father)	0.2	0.2	1.1	-0.7	-0.2	-0.2	-0.7	-1.1	0.7	-0.5	-0.3	-0.3	-0.0	-0.1	-0.2	-0.2
Irritable Bowel Disease (IBD)	0.2	0.4	1.8	-0.8	1.3	0.2	0.2	-0.8	0.4	-0.5	0.3	-0.6	0.4	-0.2	-0.5	-0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.4	0.7	0.2	0.1	1.0	0.9	-1.2	1.0	-0.7	0.7	-0.7	0.3	0.7	0.6
Body Mass Index (BMI) (2010)	0.2	0.3	1.5	-0.0	-1.1	-1.2	-0.3	-0.2	0.6	-0.1	0.4	-0.3	0.4	0.2	0.0	-0.0
Height	0.2	4.7	23.1	-2.3	1.2	-1.8	-4.8	-2.8	1.7	-2.9	1.4	-1.3	2.2	0.2	-1.5	-1.5
Allergy or Eczema	0.2	0.6	1.3	-0.6	-0.3	0.5	-1.1	-0.2	1.1	-0.6	1.0	-1.1	1.1	-0.3	-0.8	-1.0
Respiratory disease	0.2	0.4	2.7	-0.4	-0.9	1.6	-0.6	-0.2	0.5	-0.6	-0.0	-0.4	0.0	-0.2	-0.5	-0.5
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.7	-0.7	-1.6	-0.7	-0.5	-0.7	-0.6	-0.4	-0.4	-0.3	-0.2	-0.3	-0.3	-0.3
Hair Pigment	0.2	5.9	9.7	3.1	-1.3	-1.0	0.7	3.0	2.7	2.7	2.9	2.5	2.7	3.0	2.7	2.8
Sensitivity / hurt feelings	0.2	0.3	2.1	0.3	-1.0	0.3	1.4	0.3	0.3	0.1	-0.1	0.1	-0.3	-0.1	0.2	0.1
Relative age of first facial hair	0.2	0.4	1.4	0.5	1.2	0.5	0.1	0.7	1.2	0.6	0.6	0.5	0.5	0.2	0.1	0.2
Diabetes (father)	0.2	0.2	0.8	0.2	-0.5	0.3	0.9	0.1	-0.9	0.4	-0.5	0.6	-0.6	-0.1	0.3	0.2
Pack years adult smoking proportion	0.2	0.3	1.0	0.6	0.7	0.3	0.6	1.0	0.2	0.8	0.5	0.3	0.5	0.0	0.3	0.4
Townsend deprivation index at recruitment	0.2	0.3	1.5	-0.7	-0.5	-1.2	-0.1	-0.5	-0.4	-0.5	-0.6	-0.5	-0.3	-0.4	-0.6	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.5	0.0	-1.2	0.7	-0.4	-0.2	0.4	-0.3	0.4	0.1	0.4	0.3	-0.0	0.0
Chronic bronchitis/emphysema (father)	0.2	0.3	1.4	-0.2	-0.3	1.2	0.1	0.1	-0.9	-0.0	-0.5	-0.8	-0.4	-0.5	-0.3	-0.3
Body mass index (BMI)	0.2	0.9	3.7	1.1	-1.9	-0.6	1.5	1.2	0.0	1.3	-0.1	0.9	-0.3	0.5	0.7	0.8
Number of incorrect matches in round	0.2	0.4	2.4	-1.1	-0.3	0.8	-0.1	-1.6	0.1	-0.8	-0.2	0.2	-0.1	-0.1	-0.1	-0.3
Qualifications: None of the above	0.2	0.5	2.2	-0.4	-1.5	0.1	0.3	-0.2	-0.6	-0.2	-1.0	-0.7	-1.1	-0.7	-0.6	-0.6
Allergy	0.2	0.5	1.4	0.6	1.0	-1.0	1.2	0.7	-0.4	0.8	-0.3	0.7	-0.6	0.0	0.5	0.5
Arm fat percentage (right)	0.2	0.6	3.0	0.8	-1.7	-0.4	1.4	1.1	-0.1	1.1	-0.2	0.4	-0.4	0.1	0.5	0.4
Trunk fat-free mass	0.2	1.4	4.7	-0.2	-0.9	-2.2	-1.7	-0.7	1.5	-0.7	1.5	0.2	2.0	1.1	0.0	-0.1
Alcohol intake versus 10 years previously	0.2	0.3	1.9	0.0	-0.2	0.3	0.9	0.1	-1.4	0.1	-0.7	0.7	-0.7	-0.1	0.1	-0.0
Lung cancer (father)	0.2	0.2	0.7	-0.1	0.8	0.8	0.3	-0.2	-0.6	0.2	-0.6	0.3	-0.5	0.1	0.3	0.3
Illnesses of mother	0.2	0.3	1.2	0.8	0.9	-0.1	0.7	1.1	-0.2	0.4	-0.3	-0.0	-0.4	0.1	0.3	0.3
Trunk predicted mass	0.2	1.4	4.5	-0.3	-0.8	-2.1	-1.8	-0.8	1.5	-0.8	1.5	0.1	2.0	1.0	-0.1	-0.2
Standing height	0.2	1.8	7.9	-1.4	1.1	-1.6	-2.8	-2.1	0.8	-2.0	0.6	-0.3	1.1	0.3	-0.6	-0.9
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.0	0.0	0.4	1.0	0.2	0.1	-0.8	-0.2	-0.9	-0.1	-0.9	-0.4	-0.4	-0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	0.6	-0.6	-0.3	0.7	0.2	0.2	0.5	0.2	1.0	-0.0	0.6	0.9	0.9
Headache pain in last month	0.2	0.3	1.8	0.2	0.8	1.4	0.2	-0.2	0.2	0.3	0.3	0.4	0.1	0.4	0.7	0.8
High blood pressure (siblings)	0.2	0.3	1.4	0.5	-1.2	-0.4	-0.0	-0.2	0.5	0.3	-0.1	0.5	-0.4	0.8	0.8	1.0
Leg fat percentage (right)	0.2	0.6	2.4	0.7	-1.5	-0.6	1.3	0.8	-0.1	0.8	-0.1	0.6	-0.3	0.5	0.6	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	2.0	-0.5	0.0	-1.4	-0.5	-0.4	0.7	-0.3	0.6	0.1	0.7	0.4	-0.2	-0.4
Medication: Ibuprofen	0.2	0.2	0.6	-0.3	0.8	-0.1	-0.1	-0.4	-0.1	-0.6	-0.6	-0.5	-0.7	-0.5	-0.3	-0.2
Heart disease (mother)	0.2	0.2	0.8	-0.3	-0.2	-0.3	0.2	-0.4	-0.9	-0.2	-0.6	-0.1	-0.6	-0.6	-0.4	-0.5
Leg fat mass (right)	0.2	0.6	2.6	0.8	-1.6	-0.7	1.1	0.8	0.2	0.8	0.1	0.8	0.0	0.7	0.7	0.6
Number of full sisters	0.2	0.2	0.8	-0.2	-0.9	0.1	-0.0	-0.5	-0.9	-0.1	0.5	0.4	0.6	0.6	0.4	0.3
Leg pain on walking	0.2	0.3	0.7	-0.5	-0.1	0.1	-0.8	-0.5	0.2	-0.4	0.4	-0.7	0.5	-0.3	-0.8	-0.8
Whole body fat-free mass	0.2	1.0	3.9	-0.1	-1.2	-2.0	-1.4	-0.5	1.2	-0.5	1.2	0.4	1.6	0.9	0.1	-0.1
Arm fat percentage (left)	0.2	0.6	2.7	0.9	-1.6	-0.4	1.2	1.2	0.0	1.1	-0.1	0.5	-0.4	0.3	0.5	0.6
Mood swings	0.2	0.4	4.0	-0.1	0.7	2.0	-0.2	-0.3	0.3	-0.5	0.3	-0.1	0.5	0.4	0.1	-0.1
Loneliness, isolation	0.2	0.2	0.6	0.1	-0.3	0.8	-0.7	0.4	-0.1	-0.0	0.7	-0.6	0.7	0.1	-0.5	-0.3
Mineral and other dietary supplements	0.2	0.3	2.0	-0.1	-0.9	1.4	0.0	-0.1	-0.3	-0.1	-0.5	0.0	-0.6	-0.3	-0.1	-0.1
Breast cancer (self-reported)	0.2	0.3	1.6	-0.1	1.2	-0.7	-0.5	-0.1	0.8	-0.4	0.3	-0.3	0.5	0.4	0.2	0.3
Medication: Gliclazide	0.2	0.2	0.8	-0.3	-0.6	0.1	-0.8	-0.9	-0.2	-0.3	-0.2	0.3	-0.1	0.1	0.2	0.4
Whole body water mass	0.2	1.0	4.1	-0.1	-1.2	-2.0	-1.5	-0.5	1.2	-0.5	1.2	0.4	1.6	0.9	0.0	-0.1
Arm fat mass (left)	0.2	0.7	2.9	1.0	-1.7	-0.9	0.9	1.1	0.4	1.0	0.2	0.8	0.0	0.6	0.7	0.7
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.5	-0.5	-0.2	-0.2	-0.3	-0.6	-0.7	-0.5	-0.6	-0.5	-0.4	-0.4	-0.3	-0.2
Basal metabolic rate	0.2	0.9	3.7	0.2	-1.3	-1.9	-1.0	-0.2	1.1	-0.2	1.1	0.5	1.4	1.0	0.2	0.1
Average weekly beer plus cider intake	0.2	0.3	0.8	-0.7	-0.5	-0.4	-0.2	-0.6	0.6	-0.8	0.0	-0.7	0.3	-0.5	-0.8	-0.9
Ever depressed for a whole week	0.2	0.3	1.6	-0.1	0.6	1.3	-0.1	-0.1	0.4	0.1	0.6	0.6	0.6	0.6	0.5	0.4
Basal cell carcinoma (self-reported)	0.2	0.2	1.2	0.2	0.6	1.1	0.6	0.3	-0.2	0.5	0.1	0.7	0.0	0.4	0.2	0.1
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	-0.6	-0.3	-0.5	-0.3	-0.7	-0.9	-0.5	-0.9	-0.3	-0.7	-0.2	-0.1	-0.1
Impedance of whole body	0.2	0.9	5.2	-0.8	2.3	1.1	-0.2	-0.5	-0.6	-0.7	-1.0	-0.5	-1.2	-0.9	-0.6	-0.6
Leg fat mass (left)	0.2	0.6	3.0	0.8	-1.7	-0.9	1.0	0.9	0.3	0.8	0.2	0.8	0.1	0.5	0.5	0.4
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.0	0.6	-0.3	-0.2	0.7	0.4	-1.0	0.6	-0.6	0.1	-0.5	0.1	0.7	0.6
Alzheimer’s Disease (including proxy)	0.1	0.2	0.6	-0.6	0.3	0.1	-0.1	-0.4	-0.0	-0.4	-0.5	-0.8	-0.5	-0.8	-0.4	-0.1
Age at First Birth	0.1	0.2	1.3	-0.2	0.0	-1.1	-0.7	-0.2	0.5	-0.1	0.4	-0.1	0.4	0.0	-0.3	-0.1
Neuroticism (2016)	0.1	0.2	0.7	-0.5	-0.8	-0.4	-0.4	-0.2	-0.3	-0.5	0.4	-0.1	0.6	-0.1	-0.5	-0.5
Blood Red Count	0.1	0.5	2.1	-0.9	-0.0	0.7	-0.0	-0.9	-1.5	-0.3	-1.0	-0.2	-0.8	-0.6	-0.7	-0.8
BMI	0.1	0.8	4.3	1.0	-2.1	-0.3	0.5	0.9	0.8	1.1	0.6	0.7	0.5	0.9	0.6	0.7
Waist Hip Ratio (WHR)	0.1	0.6	2.5	0.9	0.4	1.6	0.8	1.1	0.7	0.7	0.2	1.0	-0.1	0.6	0.8	0.9
Lung FEV1/FVC ratio	0.1	0.5	1.8	0.0	0.4	-0.3	-0.9	-0.3	0.8	-0.0	1.4	1.3	1.2	0.7	0.2	0.3
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.8	0.3	-0.9	0.2	0.2	0.5	0.7	0.1	0.5	-0.0	0.5	0.5	0.1	-0.0
Vitamin and mineral supplements	0.1	0.1	0.4	0.0	0.4	0.6	-0.5	0.2	0.6	0.3	0.1	-0.3	-0.0	-0.1	-0.5	-0.4
Medication: Metformin	0.1	0.2	0.8	0.2	-0.5	-0.9	-0.3	0.2	-0.3	0.5	0.6	0.5	0.6	0.5	0.3	0.4
Severe depression (siblings)	0.1	0.1	0.7	-0.0	0.3	0.8	0.4	0.2	0.6	-0.0	-0.2	0.3	-0.3	-0.3	-0.2	-0.4
Impedance of leg (right)	0.1	0.7	6.2	-0.5	2.5	1.5	0.1	-0.5	-0.1	-0.6	-0.4	-0.3	-0.5	-0.2	-0.2	-0.3
Leg fat-free mass (left)	0.1	0.7	2.3	0.3	-1.5	-1.5	-0.8	-0.0	0.9	0.1	0.9	0.7	1.1	0.9	0.4	0.3
Trunk fat percentage	0.1	0.5	1.7	0.2	-1.1	-0.2	1.1	0.6	-0.8	0.5	-1.0	0.2	-1.3	-0.4	-0.0	-0.0
Age when periods started (menarche)	0.1	0.4	1.2	0.1	0.8	-0.2	-0.8	0.4	0.9	0.2	1.1	0.4	1.0	0.6	-0.1	-0.0
Stomach or abdominal pain in last month	0.1	0.1	0.7	-0.7	-0.6	0.1	-0.5	-0.8	-0.0	-0.2	-0.1	-0.1	-0.1	-0.1	-0.2	-0.2
Impedance of leg (left)	0.1	0.6	5.3	-0.7	2.3	1.0	-0.1	-0.4	-0.1	-0.7	-0.5	-0.4	-0.6	-0.6	-0.5	-0.6
Leg predicted mass (left)	0.1	0.7	2.5	0.3	-1.5	-1.6	-0.8	-0.1	0.9	0.1	0.9	0.7	1.1	0.9	0.4	0.3
Trunk fat mass	0.1	0.3	1.3	0.3	-1.2	-0.5	0.7	0.5	-0.3	0.4	-0.4	0.5	-0.6	0.1	0.2	0.1
Medication: Simvastatin	0.1	0.2	2.2	-0.3	-1.5	-0.4	-0.2	-0.2	-0.1	0.3	-0.2	0.3	-0.2	0.1	0.2	0.4
Weight	0.1	0.4	1.8	0.5	-1.3	-1.3	0.2	0.4	0.5	0.4	0.2	0.8	0.2	0.7	0.5	0.4
Impedance of arm (right)	0.1	0.4	2.0	-0.8	1.4	0.4	-0.6	-0.6	-0.1	-0.5	-0.5	-0.7	-0.6	-0.7	-0.5	-0.7
Hip circumference	0.1	0.6	3.6	0.4	-1.8	-1.9	0.5	0.2	-0.0	0.3	-0.2	0.6	-0.3	0.1	0.3	0.3
Worrier / anxious feelings	0.1	0.2	0.5	-0.4	-0.1	0.6	0.5	-0.1	0.3	-0.4	0.1	-0.6	0.3	-0.2	-0.5	-0.7
Pulse rate	0.1	0.2	1.2	-0.5	0.1	0.1	-0.2	-1.1	-0.1	-0.8	-0.0	0.2	-0.1	0.0	0.3	0.4
Medication: Cholesterol lowering	0.1	0.2	0.7	0.1	0.2	-0.3	-0.2	0.1	-0.4	0.7	-0.2	0.4	0.0	0.3	0.6	0.8
Impedance of arm (left)	0.1	0.7	3.6	-0.7	1.9	1.0	-0.7	-0.5	-0.5	-0.5	-0.8	-0.6	-0.9	-0.8	-0.5	-0.6
Arm fat mass (right)	0.1	0.5	3.5	0.6	-1.9	-0.9	0.8	0.8	0.2	0.8	0.0	0.4	-0.1	0.3	0.3	0.3
Pulse wave reflection index	0.1	0.1	0.6	0.2	0.1	0.8	0.5	0.5	-0.7	0.4	0.0	-0.1	0.0	0.0	0.2	0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	1.1	0.0	-0.2	1.0	0.6	0.1	-0.3	-0.1	-0.2	0.1	-0.1	-0.2	-0.1	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.8	0.3	-0.9	0.8	-0.6	0.3	0.2	0.2	0.1	-0.2	0.1	-0.1	0.1	0.1
Body fat percentage	0.1	0.5	1.8	0.5	-1.3	-0.3	1.2	0.8	-0.5	0.7	-0.6	0.4	-0.9	-0.0	0.3	0.3
Arm fat-free mass (right)	0.1	0.6	2.4	-0.0	-0.9	-1.6	-1.1	-0.3	0.6	-0.5	1.0	0.4	1.2	0.7	-0.0	-0.1
Medication: Seretide 50 evohaler	0.1	0.1	0.3	0.4	-0.5	0.1	-0.1	0.4	-0.5	0.0	-0.3	-0.2	-0.2	0.1	0.0	0.0
Whole body fat mass	0.1	0.5	1.9	0.7	-1.4	-0.7	1.0	0.8	-0.1	0.8	-0.2	0.8	-0.3	0.5	0.6	0.5
Arm predicted mass (right)	0.1	0.7	2.0	0.1	-1.0	-1.4	-1.2	-0.2	0.9	-0.4	1.2	0.4	1.4	0.9	0.1	0.0
Medication: Aspirin	0.1	0.2	0.6	0.1	-0.8	0.2	-0.5	0.0	0.4	0.3	-0.1	0.6	-0.1	0.4	0.4	0.6
Leg fat-free mass (right)	0.1	0.7	3.2	0.2	-1.6	-1.8	-0.8	0.0	0.9	0.1	0.8	0.6	1.0	0.7	0.2	0.1
Leg predicted mass (right)	0.1	0.7	3.3	0.2	-1.5	-1.8	-0.9	-0.1	0.9	0.0	0.8	0.5	1.0	0.7	0.2	0.1
Average weekly champagne plus white wine intake	0.1	0.2	1.7	-0.3	-0.3	0.2	-1.3	-0.4	-0.0	-0.3	0.5	-0.0	0.3	0.1	-0.1	0.1
Hearing aid user	0.1	0.1	0.7	-0.1	0.5	-0.9	-0.5	-0.1	-0.0	-0.3	0.5	-0.1	0.5	0.2	0.0	0.0
Medication: Bendroflumethiazide	0.1	0.2	1.3	0.1	-0.0	-1.1	-0.2	-0.2	-0.8	0.2	-0.3	0.5	-0.4	0.3	0.1	0.3
Leg fat percentage (left)	0.1	0.5	2.5	0.6	-1.6	-1.1	1.1	0.8	0.1	0.7	-0.1	0.5	-0.3	0.3	0.4	0.4
Arm fat-free mass (left)	0.1	0.7	3.7	0.0	-1.3	-1.9	-0.9	-0.3	0.8	-0.4	0.9	0.5	1.1	0.8	0.1	0.0
Pack years of smoking	0.1	0.2	1.0	0.5	0.3	0.4	0.6	1.0	-0.0	0.7	0.4	0.2	0.4	-0.0	0.3	0.4
Arm predicted mass (left)	0.1	0.6	3.9	0.0	-1.3	-2.0	-0.7	-0.2	0.7	-0.3	0.7	0.4	0.9	0.6	0.1	-0.1
Depression (Nagel 2018)	0.0	0.0	0.2	0.1	0.1	0.4	0.4	0.1	0.3	-0.2	-0.1	-0.2	-0.4	-0.1	-0.0	-0.0
Chronotype (morning person)	0.0	0.1	0.3	-0.3	-0.5	-0.1	0.4	-0.1	-0.2	0.0	-0.0	-0.3	-0.0	-0.5	-0.1	-0.2
Tanning	0.0	0.1	0.6	0.2	-0.8	-0.6	-0.5	0.1	0.8	0.0	0.1	0.2	0.1	0.4	-0.0	0.2
Supplements: Fish oil (including cod liver oil)	0.0	0.1	0.2	0.2	0.2	-0.5	-0.1	0.2	0.2	0.1	0.3	-0.2	0.5	0.2	0.0	-0.0

Hub : Genes

GPR160

Models

Trait associations