Hub : Genes

LMTK2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1092	0.0369	2.5e-04	0.002	NA	0.034	NA	0.027	2.1e-01	NA	1.0e-03	NA	3.0e-03
2	GTEx	Cells EBV-transformed lymphocytes	0.3320	0.1140	7.1e-03	0.203	NA	0.108	NA	0.173	3.3e-07	NA	2.2e-04	NA	2.7e-06
3	GTEx	Esophagus Mucosa	0.1440	0.0470	1.7e-05	0.048	NA	0.012	NA	0.048	3.7e-04	NA	4.6e-02	NA	3.5e-04
4	GTEx	Heart Left Ventricle	0.1731	0.0622	5.0e-04	0.008	NA	0.062	NA	0.038	1.1e-01	NA	3.1e-04	NA	4.1e-03
5	GTEx	Thyroid	0.0780	0.0270	6.5e-05	0.062	NA	0.024	NA	0.038	1.6e-05	NA	5.7e-03	NA	6.3e-04
6	YFS	Blood	0.0251	0.0103	1.7e-03	0.011	0.007	0.020	0.011	0.018	1.1e-04	0.0018	2.7e-07	0.00015	1.1e-06
7	TCGA	Bladder Urothelial Carcinoma	0.0420	0.0280	9.1e-03	0.011	0.008	-0.001	NA	-0.001	3.9e-02	0.0630	4.1e-01	NA	3.6e-01
8	TCGA	Glioblastoma Multiforme	0.1470	0.0770	6.7e-03	-0.005	0.042	-0.004	NA	0.003	5.1e-01	0.0200	4.6e-01	NA	2.5e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.4	2.2	4.5	-0.6	0.9	1.8	-0.3	2.1	1.8	1.4	1.9
Bipolar Disorder or Schizophrenia	0.4	1.0	3.8	0.8	0.9	-0.6	-0.4	0.7	2.0	-0.7	1.3
Depressed Affect (Nagel 2018)	1.4	3.0	8.3	1.7	1.6	-2.5	0.0	-2.9	1.5	-1.0	0.7
Depression (Nagel 2018)	0.3	0.4	1.3	0.2	-0.2	-0.6	1.1	-1.1	-0.2	0.0	0.0
Intelligence (Savage-Jansen 2018)	0.9	2.7	4.5	-2.1	-2.0	0.9	0.8	2.0	-2.1	-1.0	-1.7
Neuroticism (Nagel 2018)	3.9	9.2	20.6	3.6	2.4	-4.5	-1.5	-4.4	2.6	-2.3	1.1
Schizophrenia (2018)	0.8	1.7	4.9	1.6	0.5	-2.2	-0.4	-0.8	1.1	-2.1	0.1
Schizophrenia vs Biploar Disorder	0.4	0.6	1.3	0.1	-0.4	-0.6	1.1	-1.0	-0.3	-1.1	-0.6
Worry (Nagel 2018)	4.7	9.9	21.2	4.6	1.9	-4.6	-1.9	-4.5	2.1	-2.3	0.5
Alzheimer’s Disease (in mother)	0.2	0.3	0.4	0.2	0.5	0.6	-0.6	0.5	0.5	0.6	0.6
Alzheimer’s Disease (in father)	2.3	2.5	5.7	1.0	2.0	1.3	-0.2	0.8	1.9	1.8	2.4
Alzheimer’s Disease (including proxy)	0.8	1.2	3.3	0.6	1.8	1.2	-0.7	0.6	0.8	1.2	1.2
Crohns Disease (2017)	0.9	1.9	6.2	-0.1	-0.9	-0.2	2.1	2.5	0.2	-1.9	-0.1
Irritable Bowel Disease (IBD)	0.6	1.5	4.5	-0.6	-0.8	-1.0	1.8	0.7	-0.7	-2.1	-0.9
Ulcerative Colitis (UC)	0.6	1.2	3.5	-0.3	0.4	-1.9	0.7	-1.5	-0.8	-1.3	-0.9
Major Depression (MDD)	0.1	0.2	0.6	-0.6	0.2	0.0	0.8	0.3	0.2	0.2	0.3
Reaction Time	1.9	3.7	6.8	2.5	2.6	-0.5	-2.6	-1.1	1.8	1.0	2.0
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.5	-0.9	-0.9	0.7	0.7	1.2	-0.6	-0.2	-0.2
Breast Cancer	3.7	8.8	15.4	-0.2	2.8	3.8	-1.9	3.7	2.1	3.9	3.3
Ovarian Cancer	0.8	1.1	3.6	-0.2	-0.0	1.4	-0.5	1.9	0.8	0.8	1.1
Prostate Cancer	16.3	23.0	62.6	-5.3	-2.2	7.7	2.8	7.9	-0.6	4.2	2.0
Age at First Birth	0.5	0.7	1.4	1.2	-0.3	-1.1	-1.2	-0.5	0.8	-0.8	0.1
Bipolar Disorder (2011)	1.6	1.6	3.4	-1.8	-1.1	1.7	-0.1	1.8	-0.9	1.0	-0.2
Body Mass Index (BMI) (2010)	1.7	2.4	12.1	0.2	2.0	-0.4	-3.5	-1.0	0.9	0.2	1.0
Coronary Artery Disease (CAD)	1.2	1.4	2.2	-1.5	-1.4	-0.1	1.4	0.4	-1.5	-0.7	-1.4
Crohns Disease (2012)	0.9	1.5	6.2	-1.1	-1.2	0.4	1.3	2.5	-0.2	-1.1	-0.2
Mean Putamen Volume	2.0	2.3	4.4	-1.3	-2.1	-1.1	0.8	-1.5	-1.9	-0.6	-2.0
Fasting Glucose	1.8	2.2	7.0	-1.1	-0.3	-0.1	0.8	-1.5	-2.6	-0.8	-2.3
HbA1C	0.2	0.2	0.7	-0.1	0.4	-0.4	0.2	-0.7	0.2	-0.8	-0.6
HDL Cholesterol	0.7	1.2	3.7	0.5	0.4	0.7	-0.1	1.1	1.9	1.1	1.6
LDL Cholesterol	3.8	6.0	16.7	-1.5	-2.0	-1.4	0.4	-2.3	-3.7	-2.0	-4.1
Lupus	2.5	3.8	8.9	-3.0	-1.6	2.0	2.8	1.0	-1.7	1.2	-1.2
Neuroticism (2016)	0.3	0.4	1.8	0.0	1.3	-0.5	0.1	-0.3	1.0	0.0	0.6
Primary Biliary Cirrhosis	0.7	1.1	4.4	-2.1	-0.6	0.3	1.3	0.0	-1.1	0.4	-0.7
Rheumatoid Arthritis	0.5	0.7	3.8	-0.3	-0.2	-0.4	1.9	-0.6	-0.7	0.1	-0.6
Schizophrenia (2014)	0.5	1.0	3.3	0.7	-0.9	-1.4	1.0	-0.5	0.7	-1.8	-0.0
Triglycerides	0.6	0.9	4.2	-0.6	0.5	-0.3	0.4	-0.8	-2.0	0.0	-1.3
Type 2 Diabetes (T2D) (2012)	1.3	1.5	4.2	-1.8	-0.0	1.4	0.5	0.7	-2.1	0.9	-1.1
Ulcerative Colitis	0.4	0.7	2.2	-0.6	0.6	-1.5	0.3	-0.8	0.7	-0.9	0.5
Blood Eosinophil Count	0.4	3.1	7.2	0.2	-0.6	-2.2	-1.7	-2.1	-1.2	-2.7	-1.9
Blood Platelet Count	0.2	1.8	7.5	-2.7	-1.6	-0.3	1.0	0.3	-0.9	-0.7	-1.4
Blood Red Count	0.1	0.9	2.8	-0.2	-0.9	0.4	1.1	0.4	-1.7	0.1	-1.3
Blood White Count	0.5	4.0	13.5	-3.7	-2.1	2.0	1.3	2.5	-0.9	1.1	-0.2
Heel T-Score	0.3	2.2	5.4	-0.4	0.1	1.9	-0.9	2.0	1.1	1.4	2.3
BMI	0.2	1.0	2.6	0.1	1.6	-0.7	-1.6	-1.3	-0.4	-0.3	0.0
Height	0.0	0.4	1.0	1.0	-0.5	0.2	-0.9	0.7	-0.4	-0.0	-0.6
Waist Hip Ratio (WHR)	0.7	3.3	5.8	-2.2	-1.4	-1.0	-0.2	-2.4	-2.4	-1.2	-2.4
Systolic Blood Pressure	0.4	2.0	6.2	-0.1	1.1	1.7	-0.0	0.7	1.2	2.5	1.9
Smoking Status	2.6	6.2	16.2	-2.8	0.7	4.0	0.6	3.8	0.3	2.7	1.6
Allergy or Eczema	2.8	7.4	15.8	3.2	0.3	-4.0	-2.9	-3.6	1.1	-3.2	-0.5
Cardiovascular Disease	0.6	2.1	5.8	0.9	1.7	-1.8	-1.8	-2.4	-0.0	-1.0	-0.4
Hypothyroidism (self reported)	0.2	0.4	1.6	0.2	0.1	0.2	-0.6	-1.3	-0.5	0.7	-0.4
Respiratory disease	0.4	0.9	2.6	-0.1	-0.6	-1.6	-0.3	-1.3	-0.1	-1.4	-0.4
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.1	-0.8	-0.9	-0.0	0.1	-0.4	-1.3	-0.3	-1.5
Lung FEV1/FVC ratio	0.2	1.2	3.8	-0.5	-1.4	0.7	0.6	0.5	-1.9	-0.0	-1.6
Lung FVC	0.1	0.4	2.2	1.5	0.7	-0.3	0.4	-0.0	-0.2	-0.1	-0.5
Neuroticism	2.2	5.3	11.0	2.7	2.1	-3.3	-0.9	-2.4	2.8	-1.2	1.8
Chronotype (morning person)	1.3	2.9	4.5	0.8	1.4	1.9	-1.9	1.6	1.5	2.1	2.0
Hair Pigment	0.0	0.9	3.6	0.7	0.9	-1.5	-0.4	-1.9	0.1	-0.4	-0.2
Tanning	0.6	7.3	22.7	-3.4	-0.7	3.4	2.2	4.8	0.0	2.3	1.5
Hand grip strength (left)	1.0	2.5	7.3	-1.6	-0.8	2.7	0.5	2.5	-0.2	1.7	0.4
Number of treatments/medications taken	1.0	1.8	4.2	1.4	2.1	-1.4	-1.1	-1.5	1.4	-0.7	0.9
Average weekly spirits intake	1.3	1.6	3.2	-1.8	-1.6	1.7	0.6	1.7	-0.6	1.0	0.2
Sensitivity / hurt feelings	2.6	4.5	13.3	1.9	2.1	-3.3	-0.7	-3.6	1.2	-1.3	0.6
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.1	1.0	1.5	-0.3	0.6	-1.0	0.9	1.0	1.3
Hearing difficulty/problems: Yes	0.8	1.2	3.9	1.1	1.1	-1.3	-0.9	-2.0	0.6	0.2	0.7
Relative age of first facial hair	0.2	0.5	1.5	0.4	-0.9	-1.2	-0.2	-0.9	0.2	-0.6	-0.6
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	3.4	-0.5	-0.7	-0.2	-1.9	-0.7	-1.4	-0.2	-1.3
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.0	-0.5	0.5	-0.0	1.0	-0.3	0.4	0.6	0.1
Ever had hysterectomy (womb removed)	1.1	1.3	5.7	-2.4	-0.9	0.7	-0.8	0.3	-1.3	0.5	-0.8
Systolic blood pressure, automated reading	0.8	2.4	6.2	0.4	1.6	1.3	-0.5	0.1	1.7	2.5	2.3
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.5	-1.6	-0.5	0.8	1.5	0.8	-0.8	0.3	-0.3
Angina	0.2	0.3	1.0	-0.7	1.0	-0.2	-0.5	0.3	0.6	0.1	-0.1
Medication for hormone replacement therapy	0.8	0.9	2.5	-0.3	1.6	0.7	-1.3	0.9	0.2	0.9	0.9
Vitamin and mineral supplements	3.2	4.3	10.4	1.4	-0.6	-3.2	-0.7	-2.5	-1.3	-2.8	-2.4
Supplements: Zinc	0.8	0.9	2.6	-0.6	-0.6	1.6	0.5	1.4	-0.0	1.2	0.5
Medication: Co-codamol	0.5	0.6	1.3	-0.6	0.8	0.2	-1.1	1.0	0.8	0.6	0.8
Medication: Metformin	0.9	1.2	3.6	-0.7	-1.0	-0.6	-0.3	-0.8	-1.6	-0.9	-1.9
Diabetes (father)	1.6	2.0	5.1	1.2	2.2	0.3	-0.9	0.1	1.5	1.0	2.3
Diabetes (mother)	0.9	1.2	5.2	-0.1	1.1	-0.8	-0.4	-2.3	-0.8	0.3	-1.2
Severe depression (siblings)	2.1	2.4	6.5	1.2	-0.1	-2.0	-1.3	-2.5	-1.4	-1.2	-1.3
Pack years adult smoking proportion	0.3	0.4	0.7	-0.8	0.2	0.4	0.5	0.5	0.5	0.8	0.8
Impedance of leg (right)	0.3	1.3	2.9	-0.7	-0.0	1.7	0.4	1.7	0.9	1.4	0.9
Leg fat-free mass (left)	0.1	0.4	1.2	-0.1	-0.2	-0.0	-0.9	-0.6	-1.1	-0.0	-0.7
Trunk fat percentage	0.3	1.2	3.3	0.4	0.1	-1.4	-0.6	-1.8	-0.4	-1.6	-1.0
Hand grip strength (right)	0.4	1.1	3.3	0.2	0.0	1.8	-0.4	1.7	0.6	1.3	0.6
Townsend deprivation index at recruitment	1.9	2.6	5.1	-1.1	1.1	1.7	-0.9	1.5	1.7	2.2	2.3
Current tobacco smoking	4.2	6.9	17.8	-3.6	0.3	4.2	0.8	3.5	-0.2	3.1	1.3
Average weekly fortified wine intake	0.6	0.7	1.9	-0.3	-0.6	-1.3	-0.0	-0.7	-0.2	-1.4	-0.9
Maternal smoking around birth	0.6	0.8	3.1	-0.8	-0.4	1.8	-0.2	1.0	-0.9	0.7	-0.5
Fed-up feelings	0.2	0.4	1.1	0.2	0.6	-0.8	-0.5	-0.7	1.1	-0.1	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	4.3	0.2	1.7	0.3	-0.7	-0.3	1.2	1.9	2.1
Relative age voice broke	0.4	0.5	3.2	-0.1	-0.7	-0.7	-1.8	0.2	0.2	-0.3	-0.2
Taking other prescription medications	0.6	0.9	2.6	0.8	1.3	0.5	-0.9	-0.6	0.4	1.6	1.0
Age when periods started (menarche)	0.1	0.2	0.8	-0.0	0.4	0.1	0.5	0.0	0.9	0.2	0.6
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	4.4	-2.1	-0.6	1.0	1.7	1.6	-0.8	-0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.3	0.1	1.2	0.7	-0.5	0.8	0.7	1.1	0.9
Tinnitus: Yes, but not now, but have in the past	3.4	3.7	11.5	1.3	1.5	-3.1	-0.3	-3.4	-0.0	-1.8	-0.8
Qualifications: CSEs or equivalent	1.2	1.6	4.0	-1.4	-2.0	0.1	0.7	-0.4	-1.8	-0.4	-1.7
Serious illness, injury or assault to yourself	0.3	0.4	0.8	-0.9	-0.9	-0.0	0.7	0.2	-0.9	0.0	-0.4
High blood pressure	1.4	3.9	6.7	2.5	2.5	-1.8	-2.6	-2.0	1.9	-0.7	1.0
Hayfever, allergic rhinitis or eczema	1.6	3.5	7.5	2.1	-0.0	-2.7	-2.3	-2.4	0.7	-2.2	-0.3
Multivitamins +/- minerals	1.8	2.3	4.8	-1.4	0.3	2.2	1.5	2.0	0.9	1.6	1.2
Stomach or abdominal pain in last month	1.4	1.8	3.5	1.9	1.8	0.1	-0.8	-0.5	1.5	0.9	1.8
Supplements: Glucosamine	1.2	1.5	3.6	0.2	0.8	0.9	-0.8	1.5	1.8	1.0	1.9
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.8	-0.3	-0.5	-1.4	-0.3	-0.7	-0.9	-1.7	-1.6
Medication: Atenolol	0.8	1.0	2.9	0.8	1.0	-0.5	-1.3	0.3	1.7	-0.2	1.1
Medication: Levothyroxine sodium	0.4	0.6	1.3	0.1	-0.1	-0.8	-0.7	-1.2	-0.7	-0.6	-1.2
Sitting height	0.2	1.6	4.4	-0.3	0.3	2.0	-0.7	2.1	0.5	1.7	0.8
Chronic bronchitis/emphysema (father)	0.5	0.6	2.0	-0.1	-1.4	0.2	0.4	-0.7	-0.9	-0.6	-0.8
High blood pressure (mother)	0.8	1.1	2.8	0.9	-0.3	-0.8	-0.5	-1.5	-0.8	-1.2	-1.7
Body mass index (BMI)	0.4	1.5	5.2	0.4	0.7	-1.5	-1.6	-2.3	-0.4	-1.0	-0.6
Impedance of leg (left)	0.2	1.1	2.5	-0.6	0.3	1.5	0.5	1.6	1.0	1.3	0.9
Leg predicted mass (left)	0.1	0.3	1.2	-0.1	-0.3	-0.0	-0.8	-0.5	-1.1	-0.0	-0.8
Trunk fat mass	0.2	0.8	2.1	0.1	0.3	-1.1	-1.1	-1.4	-0.4	-1.1	-0.7
Waist circumference	0.4	1.5	4.8	-0.8	0.1	-1.1	-1.3	-2.2	-1.3	-0.8	-1.2
Number of incorrect matches in round	0.4	0.7	1.9	1.1	0.5	-0.8	-1.1	-1.4	0.7	-0.2	0.4
Past tobacco smoking	1.1	2.1	4.8	-1.0	-2.1	-0.9	0.6	-1.2	-1.8	-0.9	-2.2
Alcohol usually taken with meals	0.9	1.4	3.4	1.8	1.1	-0.5	-1.1	-0.3	1.8	0.1	1.4
Nervous feelings	3.3	6.2	15.0	3.2	1.4	-3.6	-2.0	-3.9	1.4	-1.7	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	4.1	0.6	0.9	0.5	0.4	-0.2	1.5	1.3	2.0
Hearing difficulty/problems with background noise	2.2	3.6	10.2	2.0	1.3	-2.6	-2.1	-3.2	0.8	-0.8	0.7
Hair/balding pattern: Pattern 2	0.6	0.8	3.1	0.2	0.4	0.2	-0.3	0.5	1.8	0.8	1.3
Had menopause	0.5	0.6	1.2	0.8	1.1	-0.6	-1.0	-0.6	0.6	-0.7	0.6
Had other major operations	0.3	0.4	0.8	-0.3	-0.8	-0.7	-0.3	-0.9	0.3	-0.8	-0.3
Forced vital capacity (FVC)	0.4	1.6	2.8	-1.0	-0.6	1.7	0.8	1.4	-1.7	1.0	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.1	-0.1	0.6	1.1	-0.5	1.1	0.6	1.1	0.7
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	5.5	0.0	0.1	-1.6	0.6	-2.4	-0.9	-0.7	-1.5
Qualifications: None of the above	0.2	0.5	3.2	-0.1	1.8	0.4	0.2	-0.1	0.0	0.4	0.5
Financial difficulties in last 2 years	0.8	1.1	3.7	-1.3	-0.0	1.1	1.9	-0.3	-0.1	1.5	0.2
Mouth/teeth dental problems	0.2	0.4	1.8	-1.3	-0.6	0.2	0.1	0.5	-0.4	0.2	-0.5
Heart attack	0.7	0.8	2.4	0.3	1.5	-0.9	-0.6	-0.4	1.3	-0.5	1.0
Allergy	1.1	2.6	7.7	-1.4	0.3	2.8	1.1	1.8	-0.6	2.5	0.3
Pain all over the body in last month	0.6	0.7	2.2	-0.9	0.6	1.3	-0.3	-0.3	-0.4	1.5	0.3
Diabetes (self-reported)	0.2	0.4	1.0	-1.0	-0.7	0.2	-0.2	-0.0	-0.7	-0.4	-0.8
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.5	0.5	-1.0	-0.1	-1.6	0.3	0.9	0.0	0.2
Medication: Ramipril	0.3	0.3	1.4	0.7	1.2	-0.3	0.3	-0.4	0.4	0.3	0.5
Medication: Simvastatin	0.3	0.5	2.0	1.0	-0.4	-0.8	0.0	-0.4	0.1	-1.4	-0.3
Fluid intelligence score	0.4	0.7	2.1	-0.9	-1.1	0.9	0.4	1.5	-0.6	-0.1	-0.6
Illnesses of siblings	0.1	0.2	1.1	-0.2	-0.1	-0.1	-1.0	0.1	-0.1	-0.1	-0.2
Neuroticism score	2.3	4.8	7.8	2.6	2.3	-2.8	-1.2	-2.5	2.7	-0.9	1.9
Weight	0.1	0.5	1.6	-0.0	0.3	-0.6	-1.3	-1.1	-0.6	-0.2	-0.5
Impedance of arm (right)	0.2	1.0	4.0	-0.5	-1.3	0.4	2.0	0.7	-0.5	-0.1	-1.2
Arm fat percentage (right)	0.5	1.9	6.1	-0.1	-0.1	-1.8	-1.1	-2.5	-0.9	-1.5	-1.3
Trunk fat-free mass	0.1	0.8	3.5	-0.1	0.5	0.7	-1.9	0.7	0.1	1.0	0.7
Hip circumference	0.1	0.3	0.8	-0.2	0.1	-0.3	-0.9	-0.9	-0.7	-0.1	-0.5
Time employed in main current job	0.7	0.8	3.3	-0.9	-1.8	0.5	-0.5	1.4	-0.0	-0.1	-0.5
Alcohol intake versus 10 years previously	0.4	0.6	2.0	-1.0	-0.1	1.4	0.4	0.1	0.1	1.4	0.1
Father’s age at death	0.4	0.6	2.1	1.4	1.0	-0.2	-0.8	0.1	0.6	-0.1	0.6
Worrier / anxious feelings	4.1	7.8	13.7	3.7	2.9	-3.1	-3.3	-3.2	2.5	-0.3	1.7
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	5.2	1.6	2.2	-1.7	-0.8	-2.3	1.0	0.3	1.3
Falls in the last year	2.4	3.3	6.1	-0.8	1.5	1.5	-1.9	2.1	2.1	1.7	2.5
Hair/balding pattern: Pattern 3	2.6	3.9	8.8	1.8	0.5	-3.0	-1.2	-2.8	-1.0	-2.6	-1.6
Number of live births	1.0	1.5	3.6	1.0	0.9	-1.9	0.9	-1.8	-0.5	-1.4	-0.6
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	6.4	-0.8	-1.6	1.2	1.0	0.8	-2.5	0.3	-2.4
Pulse rate	0.2	0.3	0.6	-0.4	-0.1	0.5	0.6	0.8	0.5	0.7	0.7
Happiness	0.5	0.6	1.3	1.1	0.9	-1.2	0.7	-0.8	-0.0	-0.5	-0.2
Noisy workplace	1.0	1.3	4.0	-0.1	0.2	-1.3	-0.3	-2.0	-0.9	-1.2	-1.5
Qualifications: A levels/AS levels or equivalent	0.9	2.0	7.6	2.8	0.9	-1.5	-1.1	-0.9	1.5	-0.8	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.9	0.9	-0.7	-0.8	-1.4	-0.8	-0.8	-1.0	-0.7
Mouth/teeth dental problems: Dentures	0.4	0.7	1.5	1.2	1.2	-0.2	-0.2	-0.1	1.1	-0.4	1.0
Asthma	0.8	1.5	4.6	0.2	-1.1	-2.1	0.4	-1.7	-0.2	-1.8	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.7	-0.0	0.7	1.6	-1.6	0.7	0.6	0.8	0.9
Medication: Cholesterol lowering	1.0	1.6	4.3	2.1	1.6	-0.8	-0.4	-0.6	1.7	-0.6	1.2
Depression (self-reported)	1.1	1.3	3.1	1.0	-0.7	-1.1	0.9	-1.8	-1.2	-1.1	-1.1
Medication: Lansoprazole	0.3	0.3	0.5	-0.3	0.5	0.6	0.4	0.7	0.5	0.5	0.6
Prospective memory result	2.0	2.5	5.9	1.7	2.4	-1.6	0.4	-1.6	1.8	-0.4	1.4
Lung cancer (father)	0.8	0.9	1.8	-1.3	-1.2	0.4	-1.2	-0.1	-1.2	-0.3	-1.0
Illnesses of mother	2.1	2.6	8.4	1.2	1.0	0.3	0.2	1.6	2.4	1.0	2.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	3.2	0.0	-0.3	1.1	-0.2	0.8	-1.8	0.7	-1.5
Pulse wave Arterial Stiffness index	1.0	1.1	3.2	-1.8	-0.6	1.2	1.5	1.1	-0.2	0.5	0.3
Impedance of arm (left)	0.3	1.3	5.4	-0.3	-1.6	0.4	2.3	0.9	-0.2	-0.5	-1.1
Arm fat mass (right)	0.3	1.3	3.6	-0.1	0.4	-1.3	-1.7	-1.9	-0.5	-1.0	-0.7
Trunk predicted mass	0.1	0.8	3.2	-0.2	0.5	0.8	-1.8	0.8	0.0	1.1	0.7
Standing height	0.1	1.5	5.0	-0.7	-0.6	1.8	0.1	2.2	-0.1	1.6	0.1
Length of working week for main job	2.8	3.1	7.2	-2.6	0.0	2.2	-1.0	2.7	0.1	2.0	0.7
Exposure to tobacco smoke at home	2.2	2.5	13.2	0.6	1.1	-2.0	0.1	-3.6	-0.5	-0.8	-0.7
Breastfed as a baby	0.5	0.6	2.4	0.5	0.4	0.7	-0.6	1.5	0.2	0.3	1.2
Tense / ‘highly strung’	3.5	5.8	12.3	3.5	2.3	-3.3	-2.3	-2.6	1.7	-1.2	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	4.2	2.0	2.0	-1.0	-0.7	-1.4	1.5	0.7	1.7
Hair/balding pattern: Pattern 4	0.5	1.1	5.5	0.3	-0.8	-0.6	2.4	-0.6	-0.5	-1.1	-0.7
Birth weight of first child	0.9	1.6	3.2	1.6	0.6	-1.6	-1.6	-1.8	0.8	-0.9	0.2
Peak expiratory flow (PEF)	0.3	0.7	2.2	0.2	-0.9	-0.2	0.2	0.1	-1.5	-0.5	-1.4
Pulse wave reflection index	1.4	1.8	4.0	-1.6	-0.4	1.7	2.0	1.7	0.4	1.1	0.8
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.6	-0.7	0.0	0.2	-0.8	0.1	-0.3	-0.3	-0.1
Loud music exposure frequency	0.5	0.5	2.2	1.0	1.5	-0.4	-0.2	-0.2	0.7	0.1	0.7
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.5	-0.7	-0.3	0.0	-0.4	-0.4	-0.0	-0.0	0.0
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.5	0.8	0.2	-1.1	0.3	-1.2	-0.4	-1.0	-0.8
Blood clot in the leg (DVT)	0.6	0.8	1.7	0.4	0.9	-1.3	-1.2	-1.2	0.9	-0.6	0.1
Medication: Paracetamol	0.2	0.4	1.1	0.2	1.0	-0.3	0.6	-1.0	0.5	-0.3	0.3
Headache pain in last month	0.4	0.7	1.5	0.5	1.1	-0.6	-0.7	-1.2	1.2	0.1	0.7
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	7.1	-2.6	-2.7	1.2	1.2	1.2	-2.3	0.3	-1.5
Glaucoma (self-reported)	0.5	0.6	2.4	0.9	-0.7	0.2	0.1	-0.2	-1.5	-0.4	-0.8
Gout (self-reported)	1.0	1.4	4.2	0.5	0.1	-1.0	-1.4	-2.0	-1.6	-0.4	-1.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	2.2	0.1	0.4	-0.2	-1.1	-1.5	-0.1	0.2	-0.2
Medication: Amlodipine	4.1	5.7	10.4	3.2	2.9	-1.5	-3.1	-1.4	3.0	-0.2	2.1
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.8	0.1	0.0	-0.9	-0.5	-0.1	0.4	-0.4	0.3
Birth weight	1.2	2.5	9.1	-0.1	-1.8	0.6	1.5	-0.4	-3.0	-0.6	-2.2
Chronic bronchitis/emphysema (mother)	2.9	3.3	8.4	0.0	-1.6	-1.2	0.5	-0.5	-2.7	-2.5	-2.9
High blood pressure (siblings)	0.2	0.4	1.0	-0.2	0.2	0.7	1.0	0.0	0.4	0.9	0.5
Forced vital capacity (FVC), Best measure	0.2	0.9	1.7	-0.0	0.6	1.3	-0.3	1.1	-1.2	1.1	-0.9
Body fat percentage	0.3	1.2	3.8	-0.0	0.1	-1.3	-0.9	-2.0	-0.6	-1.3	-1.0
Leg fat percentage (right)	0.2	0.9	2.6	0.2	0.8	-0.9	-1.6	-1.6	0.1	-0.4	0.0
Arm fat-free mass (right)	0.1	0.7	3.2	-0.1	0.8	0.5	-1.8	0.5	0.3	0.8	0.9
Exposure to tobacco smoke outside home	0.7	0.9	2.4	-1.6	1.1	1.1	-0.1	0.1	-0.7	1.4	0.0
Comparative body size at age 10	0.3	0.9	1.9	-0.9	-0.8	0.4	1.2	-0.6	-1.4	0.4	-1.2
Number of full brothers	1.2	1.4	2.8	0.0	-0.6	-1.7	1.1	-1.7	-0.5	-1.6	-1.3
Worry too long after embarrassment	2.1	3.6	8.6	2.9	1.3	-2.2	-1.3	-1.5	2.2	-1.7	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.4	8.0	-1.1	0.8	1.7	1.7	1.1	0.2	2.8	1.5
Wheeze or whistling in the chest in last year	1.2	2.1	4.2	0.9	2.0	-1.7	-1.1	-1.9	1.6	-0.4	1.3
Number of children fathered	1.9	2.1	4.6	-1.6	1.1	1.9	-1.6	0.7	-0.3	2.1	1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.2	2.5	1.6	1.6	-0.9	-1.4	-1.3	0.6	-0.5	0.5
Age at first live birth	0.4	0.7	3.7	1.9	-0.2	-0.2	-1.1	0.8	0.1	-0.5	-0.2
Pulse wave peak to peak time	0.8	1.0	2.8	1.7	0.7	-1.0	-1.5	-0.9	0.2	-0.4	-0.2
Health satisfaction	1.2	1.5	4.3	2.1	2.1	-0.5	-0.7	-1.0	0.9	0.2	1.1
Shortness of breath walking on level ground	0.5	0.6	1.3	-0.7	0.1	-1.1	0.1	-1.1	0.5	-1.1	-0.3
Qualifications: College or University degree	0.4	1.2	4.6	0.0	-2.1	-0.5	1.5	0.1	-0.6	-0.9	-1.2
Eye problems/disorders: None of the above	0.5	0.6	1.9	0.4	-0.4	-0.9	-0.2	-0.7	-0.6	-0.9	-1.4
Mouth/teeth dental problems: Loose teeth	1.9	2.3	4.5	-0.1	0.2	2.1	-1.3	1.8	1.3	1.7	1.9
Emphysema/chronic bronchitis	1.0	1.1	4.7	-0.9	0.3	1.3	-0.4	2.2	0.3	0.7	0.8
Medication for pain relief, constipation, heartburn	1.4	2.5	5.2	-2.2	-2.3	0.8	1.0	1.0	-2.0	0.4	-1.7
Neck or shoulder pain in last month	0.1	0.2	0.5	-0.4	0.5	0.3	0.2	-0.3	0.1	0.7	0.4
Medication: Blood pressure	2.5	4.4	10.3	2.6	3.2	-1.2	-2.1	-1.2	2.8	-0.1	1.9
Angina (self-reported)	0.4	0.5	1.8	-1.4	0.6	0.5	-0.3	1.1	0.5	0.6	0.1
Migraine (self-reported)	1.1	1.4	2.9	1.2	1.2	-1.7	-1.4	-1.5	0.9	-0.5	0.3
Medication: Ibuprofen	1.1	1.3	4.7	-0.8	0.2	2.2	-1.3	1.3	-0.3	1.0	0.4
Medication: Allopurinol	1.1	1.5	4.3	-0.2	0.0	-0.5	-1.3	-2.1	-2.0	0.2	-1.2
Medication: Omeprazole	0.7	0.9	2.3	1.2	1.5	-0.5	-0.5	-0.8	1.3	-0.0	0.8
Medication: Seretide 50 evohaler	0.2	0.2	0.6	-0.1	-0.6	-0.5	-0.1	0.4	-0.7	-0.4	-0.3
Mean time to correctly identify matches	2.2	4.3	9.3	3.0	2.6	-1.5	-2.8	-1.4	1.8	-0.1	1.8
Heart disease (mother)	0.4	0.5	1.7	-1.0	0.3	-0.2	-0.3	-0.4	-1.0	-0.4	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.2	0.9	-0.1	-1.1	0.8	-1.0	0.0	-0.6	-0.1
Whole body fat mass	0.2	0.9	2.9	-0.1	0.3	-1.1	-1.2	-1.7	-0.7	-1.0	-0.8
Leg fat mass (right)	0.2	0.9	3.2	0.0	1.0	-0.6	-1.8	-1.5	-0.2	-0.0	-0.0
Arm predicted mass (right)	0.2	0.9	4.1	-0.1	1.0	0.6	-2.0	0.4	0.1	0.9	0.8
Pulse rate, automated reading	1.0	3.1	7.5	-1.8	-2.5	0.8	0.8	-0.1	-2.7	-0.2	-2.5
Alcohol intake frequency.	0.3	0.6	3.5	-0.1	0.1	-0.4	0.1	-1.9	-0.8	0.8	-0.1
Comparative height size at age 10	0.5	2.8	7.7	-0.8	0.4	2.4	-0.4	2.8	1.1	2.2	1.4
Number of full sisters	0.4	0.5	2.2	1.3	-0.4	-0.0	1.5	-0.1	0.0	0.0	0.1
Suffer from ‘nerves’	4.0	6.3	17.5	3.3	1.0	-4.2	-0.7	-3.3	0.3	-2.9	-1.2
Overall health rating	0.9	1.9	5.3	0.6	2.3	-0.5	-1.9	-1.2	1.2	1.0	1.4
Chest pain or discomfort	0.4	0.6	1.5	-0.7	1.2	0.1	0.5	-1.1	0.0	1.2	0.6
Had major operations	1.4	1.7	6.6	-1.7	-1.4	0.2	2.6	0.6	-0.8	-0.0	-1.0
Age at last live birth	0.6	0.9	4.9	2.2	-0.3	-0.4	-1.4	0.3	0.1	-0.5	-0.1
Family relationship satisfaction	0.1	0.1	0.4	0.0	-0.1	-0.3	-0.1	-0.1	-0.4	0.6	-0.2
Leg pain on walking	0.3	0.3	0.9	0.2	0.9	0.3	0.6	-0.5	0.7	0.1	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.8	-0.5	0.4	0.0	0.9	-0.5	-0.6	0.9	0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.0	-1.0	-0.3	0.4	-0.4	0.5	-0.2	-0.3	-0.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.9	1.4	1.3	-0.7	-0.5	-0.1	1.2	-0.6	0.6
Medication: Aspirin	1.9	2.4	5.5	2.3	1.7	-0.2	-1.6	0.3	2.3	0.3	1.8
Supplements: Vitamin C	1.9	2.3	5.4	-1.6	-0.6	2.3	-0.8	2.0	0.1	1.7	1.6
Knee pain experienced in last month	1.1	1.7	3.7	-1.2	1.4	1.2	-1.2	0.6	1.3	1.2	1.9
Hypertension (Self-reported)	1.5	4.1	6.6	2.6	2.5	-1.9	-2.5	-2.2	1.9	-0.8	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.7	0.6	0.8	-0.8	-0.7	-0.8	0.1	-0.5	-0.1
Illnesses of father: Heart disease	0.7	1.0	2.0	1.2	0.1	-1.4	0.6	-1.4	-0.6	-1.1	-0.9
Illnesses of siblings: Diabetes	0.8	1.0	2.0	0.6	-0.5	-0.6	1.4	-1.3	-1.1	-1.0	-1.0
Smoking status: Previous	0.7	1.1	2.6	1.0	1.4	0.4	-0.5	1.0	1.3	0.4	1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	5.7	-2.4	-0.9	1.2	0.7	1.3	-1.4	0.8	-1.1
Whole body fat-free mass	0.1	0.4	2.2	-0.2	0.2	0.4	-1.5	0.2	-0.5	0.6	0.1
Leg fat-free mass (right)	0.1	0.4	1.2	0.0	-0.1	-0.2	-0.8	-0.7	-1.1	-0.2	-0.8
Arm fat percentage (left)	0.4	1.8	5.4	-0.1	-0.1	-1.7	-0.9	-2.3	-0.8	-1.6	-1.3
Average weekly red wine intake	0.2	0.4	1.5	1.2	0.0	0.0	0.4	1.0	0.4	0.0	0.5
Handedness (chirality/laterality): Left-handed	1.6	1.9	6.1	0.7	1.2	0.5	-0.3	0.7	2.3	1.2	2.5
Mood swings	1.3	2.4	4.4	1.4	1.8	-2.0	0.6	-1.7	2.1	-0.5	1.6
Loneliness, isolation	0.3	0.5	1.0	-0.4	0.9	-0.6	-1.0	-0.7	0.7	0.3	0.8
Long-standing illness, disability or infirmity	0.3	0.4	1.2	0.6	-0.1	-0.5	-0.6	-1.1	-0.7	-0.5	-0.5
Ever had bowel cancer screening	0.6	0.7	2.2	0.9	-0.2	-1.1	-0.6	-1.5	-0.0	-0.9	-0.5
Diabetes diagnosed by doctor	0.3	0.4	1.2	-0.4	-0.4	0.0	-0.8	-0.9	-1.1	0.0	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.6	-0.1	-0.5	-0.5	-1.3	-0.4	0.1	-0.4	-0.6
Friendships satisfaction	3.0	3.7	8.3	2.9	2.6	-1.5	-0.9	-1.0	2.4	0.2	2.1
Qualifications: nursing, teaching	0.9	1.4	5.3	0.1	-0.4	-0.6	-0.8	-2.3	-1.4	-0.4	-1.6
Commuting to job workplace: Walk	1.1	1.2	4.8	-0.7	-2.2	-0.1	1.6	-0.4	-1.0	-0.3	-0.7
Eye problems/disorders: Cataract	0.8	0.9	2.7	-0.4	0.5	1.0	-0.2	1.0	0.7	1.3	1.7
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	4.2	2.0	0.4	-1.7	0.5	-1.4	0.6	-0.9	-0.3
Medication for cholesterol	0.4	0.6	1.5	-0.6	-0.6	1.2	0.9	0.6	-0.7	1.1	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	6.2	0.4	1.1	-0.2	-0.6	0.1	2.5	0.7	2.3
Back pain experienced in last month	1.2	1.7	3.5	-0.4	1.8	1.3	-0.1	0.7	1.4	1.8	1.9
Mineral and other dietary supplements	0.9	1.2	3.5	-0.2	-1.3	-0.7	0.4	-0.4	-1.4	-1.2	-1.9
Breast cancer (self-reported)	0.6	0.7	3.5	0.4	-0.9	-0.7	-0.1	-0.1	-0.2	-1.9	-0.7
Asthma (self-reported)	1.0	2.0	6.5	0.5	-0.9	-2.5	0.1	-1.9	-0.2	-2.1	-0.7
Osteoporosis (self-reported)	0.1	0.1	0.2	0.0	0.4	-0.0	0.2	0.1	0.3	-0.4	0.2
Osteoarthritis (self-reported)	1.6	2.1	4.2	0.0	0.9	1.5	-1.5	1.6	1.8	1.4	2.1
Medication: Aspirin	1.5	2.0	4.8	2.2	1.3	-0.2	-1.5	0.5	2.1	0.1	1.5
Medication: Gliclazide	4.3	4.8	10.8	-1.8	-2.9	-1.0	1.1	-0.8	-3.3	-1.8	-3.3
Illnesses of father: None of the above (group 1)	1.4	1.8	4.8	-1.7	-0.8	1.6	-0.7	2.2	0.5	1.3	0.8
Smoking status: Current	3.4	5.4	14.5	-2.8	0.7	3.8	0.6	3.1	0.0	2.9	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	3.5	1.9	1.0	-0.6	-0.0	-1.3	-0.1	-0.4	-0.4
Whole body water mass	0.1	0.4	2.4	-0.2	0.3	0.5	-1.5	0.3	-0.3	0.7	0.2
Leg predicted mass (right)	0.1	0.4	1.2	-0.0	-0.2	-0.2	-0.8	-0.6	-1.1	-0.2	-0.8
Arm fat mass (left)	0.3	1.1	3.5	-0.1	0.2	-1.3	-1.2	-1.9	-0.6	-1.2	-0.9
Number of self-reported non-cancer illnesses	1.5	2.7	5.0	1.6	1.9	-2.0	-2.2	-2.1	1.0	-0.9	0.4
Average weekly champagne plus white wine intake	0.4	0.5	1.8	1.4	0.7	-0.3	-0.1	0.1	0.9	0.2	1.0
Miserableness	1.6	2.7	7.1	1.4	1.1	-2.6	0.2	-2.7	1.7	-1.2	0.6
Guilty feelings	0.7	1.0	3.3	0.8	0.6	-0.5	-0.2	0.7	1.8	-0.2	1.7
Wears glasses or contact lenses	2.8	3.2	9.1	3.0	1.0	-2.4	0.6	-1.9	1.0	-2.2	0.1
Ever taken oral contraceptive pill	1.6	1.8	3.7	-0.2	1.2	1.0	0.3	1.6	1.9	1.2	1.9
Hearing aid user	0.5	0.6	2.8	0.2	0.2	-1.0	-0.8	-1.7	0.5	-0.2	-0.1
Mother’s age at death	1.0	1.3	3.9	2.0	-1.2	-1.3	0.5	-0.4	0.9	-1.5	-0.0
Financial situation satisfaction	1.2	1.5	3.3	1.7	1.8	-1.0	-0.8	-1.0	1.5	0.1	0.9
Tinnitus: Yes, now most or all of the time	2.0	2.4	6.7	2.1	-0.4	-2.2	-0.1	-0.6	0.1	-2.6	-1.5
Commuting to job workplace: Public transport	1.1	1.4	3.4	-0.5	-0.2	1.5	1.8	1.0	0.7	1.6	0.9
Eye problems/disorders: Glaucoma	0.8	0.9	3.3	0.8	-0.9	-0.0	0.8	-0.6	-1.8	-0.7	-1.1
Medication: Blood pressure	0.3	0.6	1.3	1.1	-0.0	-1.1	-0.5	-0.6	0.6	-1.2	-0.3
Pain type(s) experienced in last month: Hip pain	1.5	1.9	5.7	0.3	1.1	0.7	0.8	2.1	1.6	0.3	2.4
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.5	-0.2	0.6	-0.0	0.7	0.2	0.7	-0.0	0.6
High cholesterol (Self-reported)	0.5	1.0	2.1	1.5	0.8	-1.4	0.3	-0.8	1.0	-1.0	0.3
Medication: Bendroflumethiazide	1.2	1.9	3.9	1.4	1.5	-2.0	-1.1	-1.8	1.0	-1.0	0.5
Medication: Paracetamol	0.2	0.3	0.9	-0.3	0.7	-0.0	0.9	-0.9	0.3	0.1	0.2
Medication: Lisinopril	1.1	1.5	3.2	1.8	1.4	-0.6	-1.4	-0.3	1.7	-0.3	1.1
Medication: Atorvastatin	0.1	0.2	0.6	-0.1	0.8	-0.0	-0.4	-0.1	0.5	0.3	0.5
Illnesses of father: High blood pressure	0.5	0.6	3.0	0.4	0.5	-1.0	-0.1	-1.7	-0.0	-0.6	-0.6
Alcohol drinker status: Never	0.7	0.9	1.9	0.9	0.9	-0.1	-0.4	-1.2	0.3	1.4	1.3
Ever smoked	0.9	1.5	3.3	0.4	1.8	0.9	0.2	1.2	1.6	1.0	1.7
Basal metabolic rate	0.1	0.4	2.2	-0.2	0.3	0.2	-1.5	-0.1	-0.5	0.4	-0.0
Leg fat percentage (left)	0.3	0.9	3.1	0.1	0.8	-1.1	-1.4	-1.8	-0.0	-0.7	-0.2
Arm fat-free mass (left)	0.1	0.7	3.3	-0.1	0.8	0.4	-1.8	0.2	0.0	0.8	0.7
Number of operations (self-reported)	0.3	0.5	2.0	-1.4	-0.2	0.1	-0.6	-0.0	-0.6	0.7	-0.7
Average weekly beer plus cider intake	1.8	2.6	6.6	-2.3	-1.1	1.2	1.0	-0.4	-2.2	0.1	-2.6
Irritability	1.1	1.8	4.3	0.9	1.6	-0.9	-1.1	-1.1	2.1	0.0	1.8
Risk taking	2.6	3.8	7.1	-2.2	1.2	1.8	0.5	2.7	1.6	2.4	2.2
Ever had prostate specific antigen (PSA) test	1.3	1.5	2.7	1.0	1.3	0.8	-0.9	1.1	1.6	1.1	1.6
Fractured/broken bones in last 5 years	0.1	0.1	0.4	-0.3	-0.3	-0.3	0.3	0.2	0.6	-0.3	0.1
Age started oral contraceptive pill	1.1	1.3	3.1	1.6	0.7	-0.8	-1.8	0.4	1.6	-0.2	1.1
Diastolic blood pressure, automated reading	0.2	0.6	1.7	-0.8	-0.2	0.7	-0.8	-1.1	-0.0	1.3	0.2
Ever depressed for a whole week	0.8	1.0	2.9	0.6	0.2	-1.7	-0.6	-1.7	0.0	-1.2	-0.7
Unable to work because of sickness or disability	5.0	6.4	13.1	-2.6	1.0	3.6	0.5	3.2	1.1	3.6	2.5
Commuting to job workplace: Cycle	0.5	0.6	1.7	-0.2	-0.7	-0.1	1.1	1.3	0.7	-0.7	-0.1
Myopia	1.8	2.6	10.9	3.3	0.3	-1.7	-1.0	-2.0	0.9	-1.1	0.3
Vascular/heart problems diagnosed by doctor	1.3	3.6	7.2	-1.9	-2.4	1.9	2.7	2.1	-1.5	0.8	-0.7
Cholesterol lowering medication	0.5	0.7	2.2	0.6	0.1	-1.5	-0.6	-0.8	0.4	-1.2	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.5	0.9	1.2	-1.0	0.2	-1.2	0.7	-0.6	0.3
Pain experienced in last month	1.3	2.2	5.4	-0.7	-2.0	0.0	1.2	1.0	-2.0	-0.9	-2.3
Supplements: Calcium	0.4	0.4	0.9	-1.0	-0.7	0.7	0.8	0.3	-0.5	0.3	0.0
Basal cell carcinoma (self-reported)	1.3	1.5	6.8	0.2	-0.2	-1.6	-0.5	-2.6	-1.0	-0.7	-1.0
Heart attack/myocardial infarction (self-reported)	0.9	1.2	3.6	0.5	1.9	-1.0	-0.6	-0.3	1.7	-0.4	1.3
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.4	0.2	0.8	-1.5	-0.9	-1.4	0.7	-0.9	-0.1
Heart disease (siblings)	0.2	0.3	1.0	-1.0	-0.3	0.5	-0.0	0.9	0.1	0.1	-0.1
Alcohol drinker status: Previous	1.4	1.6	6.0	-0.8	0.6	1.6	-0.2	2.4	0.9	1.1	1.2
Pack years of smoking	0.1	0.1	0.3	-0.6	0.1	-0.0	0.4	0.0	0.3	0.2	0.5
Impedance of whole body	0.2	0.9	3.6	-0.5	-0.9	0.9	1.9	1.1	0.2	0.2	-0.4
Leg fat mass (left)	0.2	0.8	2.6	-0.1	1.0	-0.7	-1.6	-1.5	-0.3	-0.2	-0.1
Arm predicted mass (left)	0.2	0.9	4.3	-0.2	0.9	0.6	-2.1	0.3	0.1	1.0	0.8