Hub : Traits :

Ever smoked

102 significantly associated models · 39 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 2 44448632 45864710 1 1 4.0e-11 8.5e-11 1.0e+00 100 RP11-89K21.1
2 2 47224927 48727280 1 1 2.9e-09 6.3e-07 7.8e-02 88 MSH6
3 3 84317575 86808226 1 1 1.1e-08 1.7e-14 2.3e-07 55 CADM2
4 5 86867897 88427942 1 1 1.9e-07 1.1e-06 5.0e-01 98 TMEM161B-AS1
5 6 110588546 112501537 3 1 5.1e-12 1.6e-13 3.7e-03 84 REV3L
6 7 2646223 5003373 1 1 1.3e-07 3.2e-09 6.7e-03 79 SDK1
7 7 98244565 99751521 3 1 2.2e-09 3.6e-08 8.1e-01 100 CPSF4
8 7 116660803 118207833 1 1 5.3e-11 5.4e-12 5.2e-04 75 CTTNBP2
9 9 127218258 128824378 2 1 4.3e-08 4.9e-08 2.8e-03 70 PRPS1P2
10 10 103527782 105897979 12 10 1.3e-11 1.4e-10 NaN NaN ACTR1A ARL3 AS3MT CYP17A1-AS1 NT5C2 PDCD11 RP11-332O19.5 SFXN2
11 11 58247718 59659006 1 1 8.8e-09 3.6e-09 1.0e-01 92 DTX4
12 11 112135760 113846006 1 1 4.0e-10 8.0e-36 1.3e-27 24 NCAM1
13 14 88594808 90043684 1 1 1.3e-07 8.7e-06 9.2e-01 100 TTC8
14 16 86671 1417408 2 1 2.0e-07 1.6e-07 1.5e-01 92 WDR90
15 17 1508522 2923933 1 1 7.6e-08 1.8e-07 1.0e+00 100 SRR
16 17 7431014 8850460 3 1 7.4e-08 8.4e-08 2.1e-01 94 C17orf68
17 18 20413586 21863589 1 1 3.0e-07 1.1e-05 1.2e-01 88 NPC1

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Irritable Bowel Disease (IBD) 0.99 1 0 0.0 0.00 1.0e+00 ARL3
Ulcerative Colitis (UC) 1.21 1 0 0.0 0.00 1.0e+00 CADM2
Major Depression (MDD) 2.00 1 0 0.0 0.00 1.0e+00 CTTNBP2
Reaction Time 2.60 1 0 0.0 0.00 1.0e+00 CYP17A1-AS1
Verbal and Numeric Reasoning (VNR) 1.43 1 0 0.0 0.00 1.0e+00 C17orf68
Prostate Cancer 2.81 2 0 0.0 0.00 1.0e+00 CYP17A1-AS1 SFXN2
Body Mass Index (BMI) (2010) 1.97 2 0 0.0 0.00 1.0e+00 CADM2 NPC1
LDL Cholesterol 0.87 1 0 0.0 0.00 1.0e+00 C17orf68
Schizophrenia 3.42 5 3 9.1 0.98 5.2e-04 ACTR1A ARL3 AS3MT CYP17A1-AS1 RP11-332O19.5
Blood Eosinophil Count 0.40 1 0 0.0 0.00 1.0e+00 ARL3
Blood Platelet Count 1.17 8 5 15.2 -0.75 1.9e-02 ARL3 CPSF4 CYP17A1-AS1 DTX4 MSH6 NT5C2 RP11-332O19.5 WDR90
Blood Red Count 0.39 1 0 0.0 0.00 1.0e+00 NT5C2
Blood White Count 2.04 10 7 21.2 -0.99 1.3e-08 ACTR1A ARL3 AS3MT C17orf68 CPSF4 CYP17A1-AS1 NT5C2 RP11-332O19.5 SFXN2 SRR
Heel T-Score 1.18 7 1 3.0 0.11 8.2e-01 ACTR1A AS3MT MSH6 NCAM1 PDCD11 SFXN2 SRR
BMI 2.37 9 5 15.2 -0.49 1.8e-01 ACTR1A ARL3 AS3MT CADM2 CPSF4 CYP17A1-AS1 NPC1 REV3L SRR
Height 2.02 13 8 24.2 -0.38 1.6e-01 ACTR1A ARL3 C17orf68 CPSF4 CTTNBP2 CYP17A1-AS1 NCAM1 NT5C2 PRPS1P2 RP11-332O19.5 SFXN2 SRR WDR90
Waist Hip Ratio (WHR) 1.02 2 0 0.0 0.00 1.0e+00 MSH6 PRPS1P2
Systolic Blood Pressure 2.18 7 4 12.1 0.77 2.7e-02 ACTR1A ARL3 C17orf68 CADM2 CYP17A1-AS1 NCAM1 SRR
Smoking Status 20.49 23 19 57.6 -0.98 1.0e-17 ACTR1A ARL3 AS3MT C17orf68 CADM2 CPSF4 CTTNBP2 CYP17A1-AS1 DTX4 MSH6 NCAM1 NT5C2 PDCD11 PRPS1P2 REV3L RP11-332O19.5 RP11-89K21.1 SDK1 SFXN2 SRR TMEM161B-AS1 TTC8 WDR90
Allergy or Eczema 2.90 7 0 0.0 0.70 8.0e-02 ARL3 CPSF4 CYP17A1-AS1 PDCD11 RP11-332O19.5 SFXN2 SRR
Type 2 Diabetes (T2D) 2.01 3 0 0.0 0.00 1.0e+00 ARL3 CPSF4 CYP17A1-AS1
Lung FEV1/FVC ratio 1.36 6 1 3.0 -0.70 1.2e-01 ACTR1A ARL3 CADM2 CTTNBP2 MSH6 RP11-332O19.5
Lung FVC 1.22 4 1 3.0 0.13 8.7e-01 ARL3 MSH6 PRPS1P2 WDR90
Neuroticism 3.28 8 1 3.0 0.24 5.6e-01 ACTR1A ARL3 C17orf68 CADM2 CTTNBP2 CYP17A1-AS1 PRPS1P2 TMEM161B-AS1
Chronotype (morning person) 2.01 3 0 0.0 0.00 1.0e+00 CPSF4 NCAM1 TMEM161B-AS1
Hair Pigment 0.08 1 0 0.0 0.00 1.0e+00 MSH6
Tanning 0.55 5 1 3.0 0.09 8.9e-01 CADM2 CYP17A1-AS1 PDCD11 RP11-332O19.5 SFXN2
Hand grip strength (left) 4.89 7 4 12.1 0.78 2.3e-02 ACTR1A ARL3 CADM2 CYP17A1-AS1 NT5C2 PRPS1P2 RP11-332O19.5
Sensitivity / hurt feelings 1.69 1 0 0.0 0.00 1.0e+00 PRPS1P2
Hearing difficulty/problems: Yes 1.63 1 0 0.0 0.00 1.0e+00 ARL3
Systolic blood pressure, automated reading 1.96 4 1 3.0 -0.99 8.2e-04 ARL3 CYP17A1-AS1 NCAM1 SRR
Angina 1.16 1 0 0.0 0.00 1.0e+00 TMEM161B-AS1
Pack years adult smoking proportion 3.25 1 0 0.0 0.00 1.0e+00 SFXN2
Impedance of leg (right) 1.76 8 3 9.1 -0.31 4.6e-01 ACTR1A ARL3 AS3MT CADM2 CPSF4 NCAM1 PRPS1P2 SRR
Leg fat-free mass (left) 2.52 9 5 15.2 0.49 1.2e-01 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 WDR90
Trunk fat percentage 1.23 4 1 3.0 0.53 4.7e-01 ARL3 CPSF4 NPC1 REV3L
Hand grip strength (right) 3.83 6 5 15.2 0.72 1.1e-01 ACTR1A ARL3 CYP17A1-AS1 NT5C2 PRPS1P2 RP11-332O19.5
Townsend deprivation index at recruitment 4.73 3 0 0.0 0.00 1.0e+00 ACTR1A CTTNBP2 PRPS1P2
Current tobacco smoking 9.05 13 6 18.2 0.99 5.6e-11 ACTR1A ARL3 AS3MT CTTNBP2 CYP17A1-AS1 NCAM1 NT5C2 PDCD11 PRPS1P2 REV3L RP11-332O19.5 RP11-89K21.1 SFXN2
Maternal smoking around birth 7.33 8 1 3.0 0.99 5.4e-08 ACTR1A ARL3 AS3MT CYP17A1-AS1 NT5C2 REV3L RP11-332O19.5 SFXN2
Fed-up feelings 1.44 1 0 0.0 0.00 1.0e+00 CTTNBP2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.67 1 0 0.0 0.00 1.0e+00 CTTNBP2
Age when periods started (menarche) 1.95 3 1 3.0 0.00 1.0e+00 MSH6 PRPS1P2 SRR
High blood pressure 1.43 2 0 0.0 0.00 1.0e+00 ARL3 SRR
Hayfever, allergic rhinitis or eczema 2.63 5 0 0.0 -0.52 3.7e-01 ARL3 CYP17A1-AS1 RP11-332O19.5 SFXN2 SRR
Sitting height 1.73 10 3 9.1 0.10 7.8e-01 ARL3 C17orf68 CPSF4 CYP17A1-AS1 NCAM1 NT5C2 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Body mass index (BMI) 2.08 8 3 9.1 0.56 1.5e-01 ACTR1A ARL3 AS3MT CADM2 CPSF4 NPC1 REV3L SRR
Impedance of leg (left) 1.75 7 3 9.1 -0.26 5.8e-01 ACTR1A ARL3 CADM2 CPSF4 PRPS1P2 SDK1 SRR
Leg predicted mass (left) 2.50 9 5 15.2 0.49 1.2e-01 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 WDR90
Trunk fat mass 1.81 5 2 6.1 0.53 3.6e-01 ARL3 CADM2 CPSF4 CYP17A1-AS1 NPC1
Waist circumference 2.27 6 4 12.1 0.71 1.2e-01 ARL3 CADM2 CPSF4 CYP17A1-AS1 NPC1 RP11-332O19.5
Number of incorrect matches in round 3.11 4 0 0.0 -0.64 3.6e-01 AS3MT C17orf68 CYP17A1-AS1 SFXN2
Past tobacco smoking 19.30 24 19 57.6 -0.99 8.7e-24 ACTR1A ARL3 AS3MT C17orf68 CADM2 CPSF4 CTTNBP2 CYP17A1-AS1 DTX4 MSH6 NCAM1 NPC1 NT5C2 PDCD11 PRPS1P2 REV3L RP11-332O19.5 RP11-89K21.1 SDK1 SFXN2 SRR TMEM161B-AS1 TTC8 WDR90
Alcohol usually taken with meals 3.42 2 0 0.0 0.00 1.0e+00 ACTR1A CTTNBP2
Nervous feelings 5.96 8 2 6.1 -0.84 9.0e-03 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 PRPS1P2 SRR TMEM161B-AS1
Hearing difficulty/problems with background noise 3.44 3 0 0.0 0.00 1.0e+00 ARL3 NPC1 SFXN2
Forced vital capacity (FVC) 2.05 8 1 3.0 0.38 3.6e-01 CYP17A1-AS1 MSH6 NT5C2 PDCD11 PRPS1P2 REV3L RP11-332O19.5 SFXN2
Heel bone mineral density (BMD) T-score, automated (right) 1.02 1 0 0.0 0.00 1.0e+00 NCAM1
Qualifications: None of the above 2.05 2 0 0.0 0.00 1.0e+00 ACTR1A WDR90
Mouth/teeth dental problems 2.13 1 0 0.0 0.00 1.0e+00 PRPS1P2
Heart attack 1.32 1 0 0.0 0.00 1.0e+00 TMEM161B-AS1
Allergy 2.00 4 0 0.0 0.26 7.4e-01 CYP17A1-AS1 RP11-332O19.5 SFXN2 SRR
Diabetes (self-reported) 2.02 1 0 0.0 0.00 1.0e+00 ARL3
Neuroticism score 2.55 4 0 0.0 -0.34 6.6e-01 CADM2 CTTNBP2 PRPS1P2 TMEM161B-AS1
Weight 2.59 9 6 18.2 0.76 1.1e-02 ACTR1A ARL3 AS3MT CADM2 CPSF4 CYP17A1-AS1 NPC1 RP11-332O19.5 SFXN2
Impedance of arm (right) 1.73 4 2 6.1 -0.97 3.3e-02 ACTR1A ARL3 CADM2 CPSF4
Arm fat percentage (right) 1.59 5 2 6.1 0.18 7.7e-01 ARL3 CADM2 CPSF4 NPC1 SRR
Trunk fat-free mass 2.75 11 6 18.2 0.59 3.4e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 NT5C2 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Hip circumference 2.17 8 3 9.1 0.75 3.2e-02 ACTR1A ARL3 AS3MT CADM2 CPSF4 CYP17A1-AS1 NPC1 RP11-332O19.5
Alcohol intake versus 10 years previously 2.83 2 0 0.0 0.00 1.0e+00 NT5C2 RP11-332O19.5
Worrier / anxious feelings 6.98 9 5 15.2 -0.97 3.2e-06 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 REV3L RP11-332O19.5 SFXN2 TMEM161B-AS1
Frequency of tiredness / lethargy in last 2 weeks 1.66 1 0 0.0 0.00 1.0e+00 PRPS1P2
Number of live births 1.75 1 0 0.0 0.00 1.0e+00 C17orf68
Forced expiratory volume in 1-second (FEV1) 2.26 7 1 3.0 0.09 8.5e-01 CTTNBP2 NT5C2 PDCD11 PRPS1P2 REV3L RP11-332O19.5 RP11-89K21.1
Qualifications: A levels/AS levels or equivalent 1.78 1 0 0.0 0.00 1.0e+00 ACTR1A
Forced expiratory volume in 1-second (FEV1), Best measure 1.59 3 0 0.0 0.00 1.0e+00 NT5C2 PRPS1P2 RP11-332O19.5
Impedance of arm (left) 1.97 4 2 6.1 -0.98 2.4e-02 ACTR1A ARL3 CADM2 CPSF4
Arm fat mass (right) 1.89 7 3 9.1 0.45 3.2e-01 ACTR1A ARL3 CADM2 CPSF4 CYP17A1-AS1 NPC1 SRR
Trunk predicted mass 2.74 11 6 18.2 0.58 3.6e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 NT5C2 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Standing height 2.09 10 7 21.2 0.17 6.0e-01 ARL3 C17orf68 CPSF4 CYP17A1-AS1 NCAM1 NT5C2 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Exposure to tobacco smoke at home 1.94 1 0 0.0 0.00 1.0e+00 RP11-89K21.1
Tense / 'highly strung' 2.20 2 1 3.0 0.00 1.0e+00 C17orf68 CADM2
Seen doctor (GP) for nerves, anxiety, tension or depression 2.27 2 0 0.0 0.00 1.0e+00 CTTNBP2 TMEM161B-AS1
Hair/balding pattern: Pattern 4 1.17 1 1 3.0 0.00 1.0e+00 SRR
Birth weight of first child 2.31 3 0 0.0 0.00 1.0e+00 AS3MT CYP17A1-AS1 SFXN2
Peak expiratory flow (PEF) 3.44 8 2 6.1 0.75 3.3e-02 ACTR1A ARL3 CTTNBP2 CYP17A1-AS1 NT5C2 PRPS1P2 RP11-332O19.5 SFXN2
Medication: Paracetamol 1.99 1 0 0.0 0.00 1.0e+00 C17orf68
Birth weight 1.87 3 0 0.0 0.00 1.0e+00 AS3MT CYP17A1-AS1 SRR
Forced vital capacity (FVC), Best measure 1.46 4 0 0.0 0.56 4.4e-01 MSH6 NT5C2 PRPS1P2 RP11-332O19.5
Body fat percentage 1.43 4 1 3.0 0.57 4.3e-01 ARL3 CPSF4 NPC1 REV3L
Leg fat percentage (right) 1.70 6 2 6.1 0.73 9.6e-02 ARL3 CADM2 CPSF4 NPC1 REV3L WDR90
Arm fat-free mass (right) 2.97 10 5 15.2 0.54 6.8e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Exposure to tobacco smoke outside home 5.01 4 1 3.0 1.00 2.0e-03 ACTR1A CTTNBP2 CYP17A1-AS1 RP11-332O19.5
Comparative body size at age 10 2.42 3 2 6.1 0.00 1.0e+00 CADM2 NPC1 SRR
Worry too long after embarrassment 2.51 3 0 0.0 0.00 1.0e+00 CTTNBP2 PRPS1P2 TMEM161B-AS1
Seen a psychiatrist for nerves, anxiety, tension or depression 2.02 2 0 0.0 0.00 1.0e+00 PRPS1P2 TMEM161B-AS1
Number of children fathered 1.40 1 0 0.0 0.00 1.0e+00 CADM2
Pulse wave peak to peak time 2.74 2 0 0.0 0.00 1.0e+00 CYP17A1-AS1 SFXN2
Qualifications: College or University degree 2.80 8 2 6.1 -0.83 1.0e-02 ACTR1A ARL3 CTTNBP2 CYP17A1-AS1 NPC1 PRPS1P2 SDK1 WDR90
Medication for pain relief, constipation, heartburn 2.60 2 0 0.0 0.00 1.0e+00 C17orf68 REV3L
Mean time to correctly identify matches 1.82 1 0 0.0 0.00 1.0e+00 TMEM161B-AS1
Heart disease (mother) 1.76 1 0 0.0 0.00 1.0e+00 NCAM1
Whole body fat mass 2.05 7 3 9.1 0.66 1.0e-01 ACTR1A ARL3 CADM2 CPSF4 CYP17A1-AS1 NPC1 REV3L
Leg fat mass (right) 2.52 8 4 12.1 0.75 3.1e-02 ACTR1A ARL3 CADM2 CPSF4 CYP17A1-AS1 NPC1 REV3L RP11-332O19.5
Arm predicted mass (right) 2.98 11 5 15.2 0.60 3.1e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 NT5C2 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Pulse rate, automated reading 1.54 3 1 3.0 0.00 1.0e+00 CPSF4 MSH6 WDR90
Alcohol intake frequency. 3.09 3 3 9.1 0.00 1.0e+00 CADM2 NPC1 RP11-89K21.1
Comparative height size at age 10 1.45 5 3 9.1 -0.30 5.6e-01 ARL3 CYP17A1-AS1 NPC1 RP11-332O19.5 WDR90
Number of full sisters 2.07 2 0 0.0 0.00 1.0e+00 C17orf68 CADM2
Suffer from 'nerves' 3.35 1 1 3.0 0.00 1.0e+00 CADM2
Overall health rating 1.76 1 0 0.0 0.00 1.0e+00 PRPS1P2
Age at last live birth 1.30 1 0 0.0 0.00 1.0e+00 CADM2
Qualifications: NVQ or HND or HNC or equivalent 2.37 2 0 0.0 0.00 1.0e+00 ACTR1A SDK1
Illness, injury, bereavement, stress in last 2 years 1.77 1 0 0.0 0.00 1.0e+00 CTTNBP2
Knee pain experienced in last month 2.38 3 0 0.0 0.00 1.0e+00 ACTR1A ARL3 WDR90
Hypertension (Self-reported) 1.38 1 0 0.0 0.00 1.0e+00 SRR
Smoking status: Previous 12.20 20 4 12.1 0.98 3.9e-16 ACTR1A ARL3 C17orf68 CADM2 CPSF4 CYP17A1-AS1 DTX4 MSH6 NCAM1 NPC1 NT5C2 PDCD11 REV3L RP11-332O19.5 RP11-89K21.1 SDK1 SFXN2 SRR TMEM161B-AS1 WDR90
Forced expiratory volume in 1-second (FEV1), predicted 2.14 3 0 0.0 0.00 1.0e+00 CYP17A1-AS1 SDK1 SFXN2
Whole body fat-free mass 2.68 10 6 18.2 0.51 9.3e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Leg fat-free mass (right) 2.45 10 4 12.1 0.48 1.3e-01 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Arm fat percentage (left) 1.50 6 2 6.1 0.27 6.1e-01 ARL3 CADM2 CPSF4 NPC1 REV3L SRR
Average weekly red wine intake 3.51 2 1 3.0 0.00 1.0e+00 CADM2 NPC1
Mood swings 1.19 1 0 0.0 0.00 1.0e+00 CTTNBP2
Long-standing illness, disability or infirmity 2.20 2 0 0.0 0.00 1.0e+00 REV3L TMEM161B-AS1
Diabetes diagnosed by doctor 1.99 1 0 0.0 0.00 1.0e+00 ARL3
Qualifications: nursing, teaching 1.80 1 0 0.0 0.00 1.0e+00 SDK1
Mouth/teeth dental problems: Mouth ulcers 1.46 1 0 0.0 0.00 1.0e+00 CADM2
Mineral and other dietary supplements 2.81 1 0 0.0 0.00 1.0e+00 ACTR1A
Smoking status: Current 9.37 12 5 15.2 0.99 2.9e-10 ACTR1A ARL3 AS3MT CTTNBP2 CYP17A1-AS1 NCAM1 NT5C2 PRPS1P2 REV3L RP11-332O19.5 RP11-89K21.1 SFXN2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.99 3 0 0.0 0.00 1.0e+00 ARL3 PDCD11 PRPS1P2
Whole body water mass 2.66 10 6 18.2 0.51 9.3e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Leg predicted mass (right) 2.44 10 4 12.1 0.49 1.3e-01 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Arm fat mass (left) 1.98 6 4 12.1 0.68 1.4e-01 ACTR1A ARL3 CADM2 CPSF4 CYP17A1-AS1 NPC1
Average weekly champagne plus white wine intake 1.76 1 0 0.0 0.00 1.0e+00 WDR90
Miserableness 1.68 2 0 0.0 0.00 1.0e+00 CTTNBP2 NCAM1
Supplements: Fish oil (including cod liver oil) 1.58 1 0 0.0 0.00 1.0e+00 CPSF4
Medication: Bendroflumethiazide 1.58 2 0 0.0 0.00 1.0e+00 ARL3 TTC8
Medication: Paracetamol 1.63 1 0 0.0 0.00 1.0e+00 C17orf68
Medication: Lisinopril 1.50 1 0 0.0 0.00 1.0e+00 C17orf68
Basal metabolic rate 2.65 10 6 18.2 0.52 8.4e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 SFXN2 WDR90
Leg fat percentage (left) 1.76 6 1 3.0 0.74 9.2e-02 ARL3 CADM2 CPSF4 NPC1 REV3L WDR90
Arm fat-free mass (left) 2.84 9 5 15.2 0.62 4.3e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 SFXN2
Average weekly beer plus cider intake 1.86 1 0 0.0 0.00 1.0e+00 RP11-89K21.1
Risk taking 4.17 3 1 3.0 0.00 1.0e+00 CADM2 NT5C2 RP11-89K21.1
Fractured/broken bones in last 5 years 1.52 1 0 0.0 0.00 1.0e+00 CTTNBP2
Diastolic blood pressure, automated reading 1.59 3 1 3.0 0.00 1.0e+00 NPC1 NT5C2 SRR
Unable to work because of sickness or disability 2.26 1 0 0.0 0.00 1.0e+00 C17orf68
Vascular/heart problems diagnosed by doctor 1.40 1 0 0.0 0.00 1.0e+00 SRR
Pain experienced in last month 1.85 1 0 0.0 0.00 1.0e+00 PRPS1P2
Supplements: Calcium 2.00 1 0 0.0 0.00 1.0e+00 PDCD11
Basal cell carcinoma (self-reported) 1.04 1 0 0.0 0.00 1.0e+00 SRR
Heart attack/myocardial infarction (self-reported) 1.23 1 0 0.0 0.00 1.0e+00 TMEM161B-AS1
Pack years of smoking 3.19 2 0 0.0 0.00 1.0e+00 CPSF4 SFXN2
Impedance of whole body 1.90 5 3 9.1 -0.78 1.2e-01 ACTR1A ARL3 CADM2 CPSF4 PRPS1P2
Leg fat mass (left) 2.50 9 4 12.1 0.77 1.4e-02 ACTR1A ARL3 AS3MT CADM2 CPSF4 CYP17A1-AS1 NPC1 REV3L RP11-332O19.5
Arm predicted mass (left) 2.85 9 5 15.2 0.61 4.4e-02 ACTR1A ARL3 AS3MT CADM2 CYP17A1-AS1 NPC1 PRPS1P2 RP11-332O19.5 SFXN2

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 3 0.0859 1.85
GTEx Adipose Visceral Omentum 3 0.1473 1.87
GTEx Adrenal Gland 1 0.0686 1.77
GTEx Artery Aorta 2 0.0672 1.84
GTEx Artery Coronary 1 0.0845 1.92
GTEx Artery Tibial 7 0.1861 1.82
GTEx Brain Caudate basal ganglia 0 0.0000 1.85
GTEx Brain Cerebellar Hemisphere 1 0.0672 1.92
GTEx Brain Cerebellum 4 0.2018 1.95
GTEx Brain Cortex 1 0.0966 1.92
GTEx Brain Frontal Cortex BA9 0 0.0000 1.79
GTEx Brain Hippocampus 0 0.0000 1.92
GTEx Brain Hypothalamus 2 0.3390 2.00
GTEx Brain Nucleus accumbens basal ganglia 1 0.1156 1.77
GTEx Brain Putamen basal ganglia 0 0.0000 1.69
GTEx Breast Mammary Tissue 1 0.0507 1.88
GTEx Breast Mammary Tissue (Male) 0 0.0000 1.70
GTEx Breast Mammary Tissue (Female) 0 0.0000 1.81
GTEx Cells EBV-transformed lymphocytes 2 0.1405 1.83
GTEx Cells Transformed fibroblasts 4 0.0953 1.82
GTEx Colon Sigmoid 1 0.0684 1.83
GTEx Colon Transverse 2 0.0969 1.84
GTEx Esophagus Gastroesophageal Junction 2 0.1384 1.78
GTEx Esophagus Mucosa 2 0.0602 1.77
GTEx Esophagus Muscularis 3 0.0928 1.83
GTEx Heart Atrial Appendage 0 0.0000 1.79
GTEx Heart Left Ventricle 1 0.0654 1.83
GTEx Liver 1 0.1395 2.00
GTEx Lung 4 0.1392 1.92
GTEx Muscle Skeletal 3 0.1038 1.83
GTEx Nerve Tibial 2 0.0463 1.79
GTEx Ovary 0 0.0000 1.97
GTEx Pancreas 2 0.1225 1.89
GTEx Pituitary 1 0.0897 1.81
GTEx Prostate 0 0.0000 1.81
GTEx Skin Not Sun Exposed Suprapubic 0 0.0000 1.88
GTEx Skin Sun Exposed Lower leg 3 0.0824 1.85
GTEx Small Intestine Terminal Ileum 0 0.0000 1.80
GTEx Spleen 1 0.0709 1.83
GTEx Stomach 0 0.0000 1.83
GTEx Testis 0 0.0000 1.77
GTEx Thyroid 3 0.0750 1.87
GTEx Uterus 1 0.1764 1.91
GTEx Vagina 0 0.0000 1.79
GTEx Whole Blood 1 0.0502 1.85
METSIM Adipose 7 0.1518 1.73
NTR Blood 3 0.1249 1.63
ROSMAP Brain Pre-frontal Cortex 6 0.1366 1.77
YFS Blood 2 0.0433 1.67
CommonMind Brain Pre-frontal Cortex 7 0.1302 1.73
TCGA Breast Tumor 2 0.2608 1.84
TCGA Breast Normal 3 0.0713 1.63
TCGA Ovarian Tumor 2 0.0684 1.60
TCGA Prostate Tumor 4 0.1156 1.71