TWAS hub - RRP7B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1420	0.0360	9.0e-08	0.067	0.086	0.077	0.087	0.059	1.4e-08	1.2e-10	1.1e-09	9.3e-11	1.1e-07
2	GTEx	Adipose Subcutaneous	0.3270	0.0580	2.3e-11	0.182	NA	0.197	NA	0.192	8.3e-15	NA	5.2e-16	NA	1.4e-15
3	GTEx	Artery Aorta	0.1520	0.0660	4.1e-03	0.032	NA	0.015	NA	0.039	6.7e-03	NA	4.7e-02	NA	3.1e-03
4	GTEx	Artery Tibial	0.2263	0.0702	1.6e-04	0.088	NA	0.053	NA	0.081	2.2e-07	NA	5.1e-05	NA	6.8e-07
5	GTEx	Brain Cerebellar Hemisphere	0.4840	0.1070	4.1e-04	0.133	NA	0.244	NA	0.275	2.8e-04	NA	5.9e-07	NA	9.4e-08
6	GTEx	Esophagus Mucosa	0.1260	0.0450	1.8e-03	0.103	NA	0.100	NA	0.093	2.3e-07	NA	3.2e-07	NA	8.6e-07
7	GTEx	Esophagus Muscularis	0.1410	0.0510	1.1e-03	0.111	NA	0.105	NA	0.114	3.1e-07	NA	6.0e-07	NA	2.0e-07
8	GTEx	Lung	0.0993	0.0391	3.9e-03	0.108	NA	0.110	NA	0.110	1.2e-08	NA	9.4e-09	NA	1.0e-08
9	GTEx	Nerve Tibial	0.5085	0.0715	5.3e-11	0.256	NA	0.239	NA	0.255	3.5e-18	NA	5.8e-17	NA	4.1e-18
10	GTEx	Skin Sun Exposed Lower leg	0.1760	0.0500	3.9e-06	0.044	NA	0.120	NA	0.100	1.5e-04	NA	4.2e-10	NA	1.1e-08
11	GTEx	Stomach	0.2370	0.0760	4.7e-04	0.129	NA	0.089	NA	0.115	9.9e-07	NA	4.8e-05	NA	4.0e-06
12	GTEx	Testis	0.1890	0.0810	4.8e-03	0.015	NA	0.045	NA	0.009	6.8e-02	NA	4.6e-03	NA	1.2e-01
13	GTEx	Thyroid	0.3090	0.0670	1.3e-05	0.103	NA	0.073	NA	0.079	2.9e-08	NA	3.2e-06	NA	1.2e-06
14	TCGA	Glioblastoma Multiforme	0.1560	0.0790	2.1e-03	-0.008	0.059	0.026	NA	0.004	6.5e-01	7.3e-03	5.3e-02	NA	2.4e-01
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.2121	0.0717	1.9e-04	0.010	0.031	0.040	NA	0.037	2.6e-02	1.7e-04	2.4e-05	NA	4.5e-05
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.2315	0.0677	1.6e-05	0.008	0.051	0.056	NA	0.034	3.6e-02	1.8e-06	6.1e-07	NA	8.3e-05
17	TCGA	Brain Lower Grade Glioma	0.0580	0.0278	7.8e-05	0.019	0.042	0.046	NA	0.038	2.6e-03	1.3e-05	6.1e-06	NA	3.1e-05
18	TCGA	Lung Adenocarcinoma	0.2371	0.0715	1.2e-05	0.005	0.060	0.059	NA	0.018	8.0e-02	1.4e-07	2.0e-07	NA	2.9e-03
19	TCGA	Thyroid Carcinoma	0.1060	0.0530	4.7e-04	-0.002	0.030	0.012	NA	0.002	7.1e-01	6.1e-04	2.3e-02	NA	2.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Smoking Status	4.8	11.4	30.3	5.2	3.8	4.4	3.0	1.9	3.5	3.8	4.0	3.1	-0.6	3.7	1.9	2.7	5.5	-0.2	0.7	5.1	2.4	2.3
Smoking status: Current	4.7	7.4	27.9	5.3	2.8	3.0	2.3	0.9	2.5	3.0	2.4	1.9	-0.1	2.1	2.3	1.5	5.0	-1.0	-0.2	4.8	1.6	1.4
Relative age voice broke	4.6	7.0	16.1	-3.8	-2.9	-3.1	-2.6	-2.3	-2.9	-2.3	-2.8	-2.6	-0.9	-2.4	-3.9	-2.2	-3.6	1.1	0.4	-4.0	-1.2	-1.5
Financial situation satisfaction	4.6	5.7	10.8	1.3	3.0	3.0	2.6	3.1	3.3	3.2	3.1	3.0	1.2	3.0	0.8	3.0	1.7	-1.3	-1.3	2.6	0.3	0.2
Illness, injury, bereavement, stress in last 2 years	4.5	5.5	11.5	-2.0	-2.7	-3.1	-2.0	-2.7	-3.4	-3.4	-2.8	-2.8	-0.6	-2.8	-2.3	-2.6	-2.0	-0.1	0.0	-2.7	-0.8	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	4.0	5.4	8.9	1.4	3.0	2.7	2.5	2.4	2.9	2.8	2.9	3.0	0.2	2.8	3.0	2.4	2.4	-0.2	0.0	3.0	1.0	0.9
Diverticular disease/diverticulitis (self-reported)	3.9	4.6	7.5	2.6	2.2	2.7	2.1	1.1	2.4	2.6	2.5	1.8	-0.8	2.1	0.8	1.9	2.6	1.4	1.8	2.7	2.4	2.6
Qualifications: A levels/AS levels or equivalent	3.8	8.3	21.3	-3.1	-3.1	-3.6	-2.5	-2.0	-3.3	-3.5	-3.1	-2.8	0.4	-2.9	-2.7	-2.4	-4.2	-0.9	-1.1	-4.6	-2.2	-2.9
Primary Biliary Cirrhosis	3.7	5.2	10.0	2.2	2.3	2.7	2.8	1.7	2.9	2.7	2.9	2.8	0.8	2.6	0.2	2.5	2.4	0.6	0.6	3.2	1.5	2.5
Current tobacco smoking	3.7	6.1	23.9	4.9	2.5	2.8	2.1	0.7	2.2	2.7	2.2	1.5	0.0	1.8	2.3	1.3	4.5	-0.8	0.1	4.2	1.6	1.3
Qualifications: College or University degree	3.6	11.2	22.0	-3.9	-4.5	-4.7	-3.4	-2.4	-4.2	-4.1	-3.8	-3.4	-0.8	-3.3	-3.2	-3.3	-4.5	0.7	-0.0	-4.3	-1.3	-2.5
Relative age of first facial hair	3.5	7.3	20.4	-3.2	-2.2	-3.2	-2.4	-2.6	-3.1	-2.5	-2.9	-3.0	-1.0	-2.6	-3.0	-2.3	-4.1	0.1	-0.4	-4.5	-2.5	-1.4
Financial difficulties in last 2 years	3.4	4.5	8.9	2.7	2.7	2.6	2.2	2.4	3.0	2.7	2.4	2.4	1.4	2.1	1.9	2.3	1.8	-1.2	-1.0	2.1	0.5	0.6
High cholesterol (Self-reported)	3.4	6.0	11.5	0.9	2.9	3.4	2.5	2.5	2.8	3.0	3.0	3.2	-0.0	3.0	2.2	3.1	1.8	1.2	1.1	2.6	0.6	2.9
Alcohol drinker status: Never	3.4	4.0	9.2	2.7	1.8	2.0	1.9	0.9	1.9	2.3	1.5	1.4	-1.4	1.4	3.0	0.9	2.9	1.3	1.7	2.9	1.5	2.7
Pain type(s) experienced in last month: Hip pain	3.3	4.1	13.3	2.8	2.1	2.3	1.8	0.9	2.4	2.5	2.1	1.7	-0.1	1.7	3.6	1.5	2.5	0.8	1.0	2.4	2.1	0.8
Commuting to job workplace: Car/motor vehicle	3.2	3.7	8.0	2.2	2.2	2.3	1.5	1.4	2.3	2.3	2.3	2.0	-0.5	2.3	1.0	1.9	2.5	0.2	0.6	2.8	0.8	2.3
HbA1C	3.1	3.5	7.1	-0.6	-2.4	-2.1	-2.2	-2.4	-1.7	-1.7	-2.5	-2.2	-0.7	-2.7	-0.6	-2.3	-2.1	1.3	0.9	-2.4	0.2	-1.3
Migraine (self-reported)	3.1	3.8	13.4	3.7	1.0	1.2	0.6	-0.8	1.0	1.4	1.1	0.3	-3.3	0.5	0.1	-0.0	3.1	2.0	2.2	2.7	1.8	3.2
Had other major operations	3.0	3.7	9.3	1.2	2.3	2.5	0.9	2.2	1.4	1.5	2.0	1.8	2.6	2.3	3.0	1.7	1.2	-1.9	-2.4	1.5	-0.4	-1.7
Lung cancer (father)	2.9	3.4	14.2	3.8	1.2	1.1	1.2	0.1	1.6	1.6	1.2	0.9	-1.9	1.1	-0.5	0.5	2.2	2.4	2.1	2.6	1.6	3.0
Alcohol intake frequency.	2.9	6.8	17.1	3.4	2.7	3.2	2.2	1.2	3.3	3.5	2.3	2.0	-1.1	1.7	2.3	1.8	3.3	1.2	2.2	3.2	1.9	4.1
Arm fat percentage (left)	2.9	11.5	21.3	3.4	3.6	4.6	3.6	3.1	4.5	4.2	4.1	3.8	1.1	3.6	4.0	3.3	3.1	1.1	1.1	3.9	2.8	2.2
Depression (Nagel 2018)	2.8	4.2	7.5	1.9	2.4	2.3	2.0	1.8	2.5	2.7	2.3	2.3	-0.6	2.2	1.7	1.8	2.5	1.1	1.1	2.1	2.3	1.8
Birth weight of first child	2.7	5.0	10.7	-3.0	-2.9	-2.1	-2.8	-2.1	-2.6	-2.8	-2.5	-2.5	-0.9	-2.4	-0.8	-2.2	-2.5	-0.2	-0.3	-3.3	-0.5	-1.9
High blood pressure (siblings)	2.6	3.8	8.5	1.2	2.1	2.7	2.3	1.5	2.7	2.9	2.0	2.3	-0.7	1.9	2.2	1.9	1.9	-0.5	-0.6	2.6	-0.1	1.5
Chronic bronchitis/emphysema (father)	2.5	2.9	5.9	0.8	1.8	2.3	1.2	1.6	2.2	2.4	1.8	2.0	-0.1	2.0	2.1	1.7	1.4	1.4	1.1	1.4	2.2	0.9
Qualifications: None of the above	2.5	5.3	11.4	2.9	2.5	3.4	1.9	1.6	2.4	2.2	2.5	2.2	-0.8	2.2	2.6	2.0	3.0	0.8	1.3	3.3	1.4	2.5
Had major operations	2.5	2.9	14.3	1.8	1.9	1.3	1.0	1.5	1.7	1.9	1.4	1.7	0.5	1.6	3.8	1.2	2.5	0.4	0.1	2.5	0.7	0.8
Breast cancer (self-reported)	2.4	2.9	7.3	-1.5	-1.7	-2.0	-2.7	-0.7	-2.5	-2.3	-2.0	-1.8	0.4	-1.5	-0.6	-1.7	-1.3	-0.7	-1.0	-1.9	-1.6	-2.0
Average weekly fortified wine intake	2.3	2.7	9.6	-2.0	-1.1	-2.1	-1.0	-0.7	-1.7	-1.0	-1.8	-1.3	1.2	-1.3	-0.9	-1.2	-2.9	-0.9	-0.5	-3.1	-1.0	-2.4
Asthma	2.3	4.6	9.4	-0.3	2.8	2.7	2.5	2.9	2.8	2.6	2.7	3.0	0.9	3.1	1.9	3.0	0.2	0.1	-0.3	1.8	-0.2	0.6
Wheeze or whistling in the chest in last year	2.3	4.2	8.2	2.1	1.8	2.9	2.2	1.7	2.5	2.8	2.4	2.5	-0.3	2.7	2.4	1.9	2.1	0.3	-0.3	2.7	1.0	0.6
Age at first live birth	2.3	4.1	11.0	-3.1	-1.9	-2.7	-1.4	-0.7	-1.9	-2.1	-1.8	-1.5	-0.6	-1.5	-3.3	-1.2	-3.2	-0.7	-0.7	-3.1	-1.4	-1.6
Number of operations (self-reported)	2.3	3.4	18.7	2.1	2.3	2.3	1.1	1.4	1.6	1.9	1.6	1.5	1.2	1.5	4.3	1.2	2.3	-1.0	-0.8	2.2	0.4	0.1
Alzheimer’s Disease (in mother)	2.2	2.6	5.8	0.9	2.1	1.9	1.8	1.9	2.0	2.4	2.0	1.9	-0.2	2.0	1.0	1.8	1.5	-0.1	0.6	2.1	0.6	0.9
Verbal and Numeric Reasoning (VNR)	2.2	5.3	11.1	-1.2	-2.5	-2.4	-2.3	-1.4	-2.3	-3.1	-1.9	-2.3	1.9	-2.0	-2.5	-2.0	-3.3	-1.1	-1.9	-3.2	-1.5	-3.1
Lupus	2.2	3.3	6.3	0.7	2.0	2.4	2.4	2.1	2.5	2.3	2.1	2.2	0.9	2.2	1.0	2.2	1.4	0.1	0.5	2.0	1.6	1.4
Trunk fat percentage	2.2	8.6	15.3	2.6	3.1	3.9	2.8	3.0	3.9	3.8	3.5	3.4	1.1	3.4	3.5	2.9	2.4	1.0	1.2	3.0	3.1	0.9
Multivitamins +/- minerals	2.2	2.8	5.9	0.5	2.4	2.1	2.2	1.6	1.9	2.2	2.3	2.1	0.7	2.2	0.6	2.4	1.2	0.3	0.4	1.6	0.4	1.3
Arm fat percentage (right)	2.2	8.6	16.4	3.2	2.9	4.1	3.0	2.4	3.9	3.6	3.5	3.1	1.0	3.0	3.6	2.7	2.9	1.0	0.9	3.5	2.6	2.0
Body fat percentage	2.2	8.7	15.6	2.9	3.1	3.9	3.0	2.8	4.0	3.9	3.4	3.3	0.9	3.2	3.7	2.8	2.6	1.1	1.1	3.1	3.0	1.2
Asthma (self-reported)	2.2	4.5	9.1	-0.2	2.8	2.8	2.4	2.7	2.8	2.5	2.8	2.9	0.8	3.0	1.8	3.0	0.2	0.2	-0.2	1.7	-0.3	0.9
Ever smoked	2.2	3.9	7.7	1.8	2.7	2.4	1.9	2.0	2.2	2.4	2.4	2.1	1.3	2.5	0.9	2.0	2.7	-0.3	-0.0	2.8	1.0	0.8
Bipolar Disorder (2018)	2.1	3.3	8.1	0.6	-2.1	-1.9	-2.1	-2.7	-2.1	-1.9	-2.5	-2.5	-0.6	-2.8	1.2	-2.6	-0.5	0.0	0.0	-1.6	1.2	-1.2
Long-standing illness, disability or infirmity	2.1	3.2	6.8	0.5	2.5	2.6	1.3	1.8	2.2	2.4	2.2	2.2	0.4	2.3	2.5	2.3	0.9	0.0	-0.1	1.6	-0.3	1.5
Taking other prescription medications	2.0	3.1	10.4	-0.0	2.8	2.3	1.1	2.3	1.8	1.9	1.8	2.1	1.9	2.2	3.2	2.1	0.9	-0.5	-0.2	1.2	0.1	0.1
Age when periods started (menarche)	2.0	4.7	10.1	-2.6	-2.0	-3.0	-2.3	-1.6	-2.6	-2.0	-2.4	-2.1	-1.3	-1.9	-2.6	-2.0	-2.8	1.6	0.8	-3.2	-0.4	-2.0
Trunk fat mass	2.0	8.4	15.7	2.3	3.0	3.9	2.9	3.0	4.0	3.7	3.6	3.5	0.8	3.4	3.2	3.0	2.3	1.3	1.3	3.0	3.0	1.2
Exposure to tobacco smoke outside home	2.0	2.6	7.5	2.2	1.6	1.5	1.2	0.6	1.2	1.6	1.5	1.1	0.4	1.3	1.3	1.2	2.4	-2.5	-2.2	2.7	-1.2	0.0
Bipolar Disorder (2011)	1.9	1.8	6.8	0.0	-1.4	-1.3	0.0	-2.6	-1.6	-1.1	-1.9	0.0	-1.4	-2.2	2.1	-2.4	0.0	0.0	0.0	0.0	0.0	0.0
Respiratory disease	1.9	4.3	10.1	-0.5	2.6	2.6	2.3	2.6	2.5	2.4	2.7	2.8	1.1	3.2	2.3	2.8	0.1	0.0	-0.3	2.1	-0.4	0.4
Vitamin and mineral supplements	1.9	2.6	6.6	0.2	-2.0	-2.1	-1.8	-1.7	-1.9	-2.1	-2.3	-2.3	-1.2	-2.3	-0.0	-2.6	-0.4	0.0	0.6	-1.1	-0.0	-0.4
Alcohol usually taken with meals	1.9	3.1	7.6	-2.1	-2.2	-2.1	-1.3	-1.5	-1.7	-1.5	-1.5	-1.4	-2.6	-1.5	-2.8	-1.3	-1.5	2.4	1.8	-1.2	0.4	0.8
Friendships satisfaction	1.9	2.3	4.6	1.3	2.0	2.0	1.1	1.6	2.1	1.4	1.9	1.8	-0.2	1.7	0.6	1.4	1.7	0.7	1.1	1.9	1.6	1.1
Osteoarthritis (self-reported)	1.9	2.5	8.6	2.3	1.8	1.9	1.1	1.1	1.6	1.3	1.8	1.3	0.6	1.8	2.9	1.1	2.0	0.1	-0.2	2.2	0.9	0.4
Alzheimer’s Disease (including proxy)	1.8	2.5	6.3	0.2	2.2	2.2	1.1	2.5	2.0	2.4	1.8	1.9	0.2	2.0	0.8	1.9	1.2	0.2	0.8	1.7	1.0	0.7
Coronary Artery Disease (CAD)	1.8	2.1	5.0	-1.6	-1.8	-1.9	0.0	-1.0	-2.1	-2.2	-2.1	-1.9	-0.1	-1.9	-1.1	-1.7	-1.7	0.5	0.0	0.0	-0.4	-1.2
Body mass index (BMI)	1.8	7.7	16.0	2.7	2.8	4.0	3.1	2.5	3.8	3.2	3.3	3.0	0.6	2.8	3.2	2.7	2.5	1.0	0.8	3.2	2.0	2.3
Allergy	1.8	4.1	11.6	0.3	-2.7	-2.2	-1.5	-2.6	-2.5	-2.4	-2.5	-2.7	-0.4	-2.7	-3.4	-2.5	-1.1	-0.0	-0.3	-2.0	-0.7	0.0
Intelligence (Savage-Jansen 2018)	1.7	5.3	12.2	-0.9	-2.3	-3.2	-2.1	-1.0	-2.6	-3.1	-2.4	-2.4	1.5	-2.3	-1.7	-2.3	-3.3	0.6	0.1	-3.3	-0.1	-3.5
Mean Putamen Volume	1.7	1.9	5.6	2.4	1.5	1.1	1.2	0.5	1.1	2.1	1.3	1.2	-0.9	1.2	1.6	0.9	2.1	-0.5	-0.5	1.9	-0.3	1.5
Prospective memory result	1.7	2.0	6.5	1.2	-1.6	-1.4	-0.8	-2.6	-1.4	-0.9	-1.7	-1.9	-1.9	-2.0	1.0	-1.9	0.1	1.0	1.0	-0.6	-0.3	1.4
Loud music exposure frequency	1.7	1.8	8.9	2.5	0.3	0.6	0.9	-0.3	1.2	1.3	0.9	0.5	-1.9	0.4	-0.1	0.3	3.0	-0.5	-0.7	2.9	0.8	0.1
Medication: Ventolin 100micrograms inhaler	1.7	2.2	5.6	-0.9	1.4	1.6	1.6	2.3	1.7	1.7	1.8	2.2	1.4	2.4	0.8	2.0	0.2	0.4	-0.6	1.3	0.2	-0.2
Medication: Gliclazide	1.7	1.9	4.4	0.2	1.7	2.1	1.2	2.1	1.7	1.1	1.5	1.7	1.4	1.7	2.1	1.5	0.6	-0.4	-0.6	1.0	0.6	-0.9
Body Mass Index (BMI) (2010)	1.6	2.2	4.4	0.2	1.7	1.6	1.8	1.9	1.6	1.7	1.7	1.9	-0.4	1.9	1.7	1.5	1.9	-0.2	0.0	2.1	0.6	0.8
BMI	1.6	9.1	17.8	3.7	3.1	4.0	3.5	2.2	4.1	3.8	3.4	2.9	-0.3	3.0	3.3	2.8	3.1	0.7	0.6	4.2	1.7	2.8
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.6	6.5	1.1	1.9	2.2	1.4	2.1	2.1	2.2	2.2	2.3	1.1	2.5	0.4	2.0	1.9	1.3	1.4	2.1	2.4	1.6
Alcohol intake versus 10 years previously	1.6	2.4	6.6	2.2	1.1	1.5	0.6	0.6	1.7	2.2	1.1	0.9	-1.8	0.8	0.5	0.7	2.2	1.1	2.0	1.4	2.6	2.1
Noisy workplace	1.6	1.9	6.3	0.7	-0.9	-0.8	-1.4	-1.8	-0.8	-0.8	-1.1	-1.2	-2.1	-1.4	2.5	-1.7	0.8	1.8	2.1	-0.1	1.2	0.7
Mouth/teeth dental problems: Dentures	1.6	2.7	6.8	2.6	1.9	2.1	1.4	0.5	1.5	1.3	1.6	1.3	-1.0	1.5	1.4	1.2	1.8	1.2	1.4	2.3	0.8	2.5
Ever highly irritable/argumentative for 2 days	1.6	2.0	4.1	2.0	2.0	1.9	1.1	1.2	1.8	1.4	1.7	1.5	0.2	1.3	1.4	1.3	1.7	-0.9	-0.4	1.8	0.1	0.1
Gout (self-reported)	1.6	2.1	6.9	0.5	-1.9	-1.5	-0.9	-2.0	-1.5	-1.4	-1.4	-1.8	-1.9	-1.8	-2.6	-1.8	0.3	0.2	0.7	-0.9	1.3	0.2
Leg fat percentage (right)	1.6	5.6	10.4	2.9	2.2	3.2	2.5	2.0	3.2	3.2	2.6	2.5	0.3	2.2	2.8	2.0	1.9	1.4	1.4	2.4	2.6	1.6
Whole body fat mass	1.6	6.6	12.4	2.4	2.6	3.5	2.6	2.5	3.5	3.2	3.1	3.0	0.6	2.9	3.1	2.5	2.1	1.1	0.9	2.7	2.5	1.1
Mood swings	1.6	2.9	7.5	0.7	1.6	1.8	1.4	1.1	1.9	2.5	1.9	1.7	-1.1	1.8	0.1	1.5	2.2	1.2	1.7	2.0	2.7	1.4
Back pain experienced in last month	1.6	2.4	10.3	-0.3	2.2	1.7	0.8	2.0	1.5	1.2	1.7	1.7	1.6	1.8	3.2	1.8	-0.1	-0.9	-1.1	0.5	-0.4	-1.2
Arm fat mass (left)	1.6	6.6	12.7	2.6	2.6	3.6	2.7	2.3	3.5	3.0	3.1	2.8	0.5	2.8	3.3	2.5	2.4	1.0	0.8	3.0	2.3	1.6
Cholesterol lowering medication	1.6	2.4	9.5	0.3	1.8	2.2	0.8	1.9	1.4	1.9	1.5	1.7	0.8	1.9	3.1	1.6	1.1	1.1	0.7	1.1	1.3	0.5
Blood White Count	1.5	11.3	23.8	2.4	4.9	4.7	4.2	3.7	4.3	3.4	3.6	3.6	3.9	3.7	3.6	3.4	2.4	-1.6	-1.5	3.2	-0.1	0.6
Lung FEV1/FVC ratio	1.5	7.8	18.6	-1.4	-3.2	-3.5	-3.4	-2.7	-3.3	-2.9	-4.2	-3.6	-0.2	-4.3	-0.3	-3.9	-0.4	-2.0	-1.0	-2.8	-0.3	-2.9
Number of treatments/medications taken	1.5	2.7	7.1	0.0	1.9	2.4	0.6	1.6	1.6	1.7	1.8	1.9	0.0	2.1	2.7	1.7	1.3	1.3	1.3	1.7	1.5	1.5
Time employed in main current job	1.5	1.7	4.2	-1.0	-1.6	-1.4	-1.7	-1.0	-1.5	-1.2	-1.7	-1.3	0.1	-1.3	1.2	-1.5	-1.5	0.5	0.5	-2.1	0.7	-1.7
Emphysema/chronic bronchitis	1.5	1.7	6.4	1.7	1.3	1.4	0.6	0.7	1.2	1.7	1.0	1.0	0.1	1.0	1.6	0.7	2.5	0.2	0.5	2.2	1.1	1.1
Leg fat mass (right)	1.5	5.9	11.5	2.7	2.2	3.3	2.6	2.1	3.4	3.1	2.8	2.6	0.1	2.5	2.7	2.2	2.1	1.4	1.1	2.7	2.6	1.6
Qualifications: nursing, teaching	1.5	2.3	4.6	-1.3	-2.0	-1.9	-1.3	-1.6	-1.9	-1.6	-1.7	-1.6	-0.4	-1.6	-1.8	-1.6	-1.9	0.7	0.9	-2.1	-0.2	-0.1
Medication: Lisinopril	1.5	2.0	4.0	1.1	2.0	2.0	2.0	1.1	1.7	1.3	1.4	1.4	1.7	0.9	1.6	1.4	1.1	-1.4	-0.4	1.6	-0.5	0.7
Type 2 Diabetes (T2D) (2012)	1.4	1.6	3.0	1.1	0.9	1.6	1.3	0.8	1.2	1.6	1.4	1.1	-0.0	1.3	1.4	1.1	1.7	0.5	1.0	1.3	1.6	1.7
Ever used hormone-replacement therapy (HRT)	1.4	1.8	4.0	1.7	1.4	1.5	1.7	0.2	1.4	1.8	1.4	0.9	-1.5	1.1	1.8	0.9	2.0	0.3	0.1	1.9	0.7	1.0
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	4.0	1.2	0.8	1.5	1.0	0.4	1.5	0.8	1.4	0.8	-1.6	0.8	1.0	0.9	1.5	1.1	1.2	1.7	0.9	2.0
Supplements: Glucosamine	1.4	1.8	4.5	-0.4	-1.2	-1.3	-1.3	-1.0	-1.9	-2.1	-1.3	-1.5	0.6	-1.2	0.3	-1.3	-0.9	-1.4	-1.4	-1.6	-1.0	-2.1
Impedance of leg (left)	1.4	6.7	15.1	-1.3	-3.2	-3.9	-3.3	-2.8	-3.4	-2.2	-3.4	-2.9	-1.2	-3.1	-2.0	-3.1	-1.5	0.0	0.2	-2.9	0.5	-2.8
Medication: Lansoprazole	1.4	1.6	7.3	1.6	0.2	0.5	0.1	-0.4	0.5	0.9	0.4	0.1	-1.7	0.2	0.3	0.1	1.9	1.7	2.5	1.2	2.7	1.5
Arm fat mass (right)	1.4	5.7	10.9	2.6	2.2	3.3	2.4	1.9	3.2	2.8	2.8	2.5	0.3	2.4	3.0	2.1	2.3	1.3	1.1	2.7	2.5	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.2	5.6	1.6	2.0	1.8	1.1	0.8	1.9	2.4	1.4	1.3	-0.3	1.1	1.2	1.3	1.5	1.3	1.5	1.3	1.6	1.5
Headache pain in last month	1.4	2.4	6.0	2.1	1.6	1.6	1.1	-0.1	1.3	1.3	1.3	0.9	-1.7	0.9	2.3	0.4	2.5	1.2	1.5	2.3	1.2	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	3.8	0.4	-1.4	-0.9	-1.8	-2.0	-1.9	-1.8	-1.3	-1.7	-1.7	-1.3	-0.7	-1.7	-0.2	1.2	1.0	-0.3	-0.1	0.5
Leg fat mass (left)	1.4	5.3	10.6	2.5	2.1	3.1	2.4	2.0	3.3	3.0	2.7	2.6	0.0	2.4	2.6	2.2	1.8	1.5	1.1	2.4	2.5	1.4
Blood Eosinophil Count	1.3	10.4	22.0	-0.2	4.7	3.0	4.1	4.5	4.4	4.3	3.9	4.4	3.0	4.1	1.6	4.2	1.6	-0.1	0.4	1.8	1.6	1.1
Frequency of depressed mood in last 2 weeks	1.3	1.9	5.0	1.1	0.9	1.5	1.0	0.7	1.6	1.7	1.6	1.3	-1.3	1.2	0.1	1.3	0.8	1.9	1.7	0.8	2.2	1.7
Medication: Co-codamol	1.3	1.5	5.6	0.5	0.8	1.4	1.5	1.1	1.0	0.3	1.1	1.0	2.3	0.7	0.8	1.1	0.3	-2.4	-2.1	0.4	-0.8	-0.9
Diabetes (father)	1.3	1.6	4.5	1.1	1.3	1.4	1.7	0.8	1.5	2.1	1.1	1.2	-0.5	1.0	1.2	0.9	1.7	-0.9	-0.3	1.4	0.1	1.6
Past tobacco smoking	1.3	2.4	5.9	-0.9	-2.3	-2.1	-1.2	-1.8	-1.6	-1.9	-2.0	-2.0	-0.7	-2.4	-0.9	-1.8	-1.5	-0.2	0.1	-1.9	-0.6	-0.2
Worry too long after embarrassment	1.3	2.2	6.5	-2.3	-1.5	-1.7	-2.1	-0.8	-1.9	-2.1	-1.7	-1.2	0.6	-1.3	-0.5	-1.4	-0.6	-0.8	-0.8	-1.0	-0.3	-2.5
Shortness of breath walking on level ground	1.3	1.5	3.6	1.8	1.2	1.9	1.5	0.5	1.4	1.4	1.6	0.9	-0.7	1.3	0.4	1.1	1.2	0.6	0.8	1.4	1.3	1.0
Mineral and other dietary supplements	1.3	1.8	3.8	0.4	1.6	1.4	1.8	2.0	1.9	1.6	1.3	1.7	0.7	1.4	0.3	1.3	0.7	-0.2	0.7	1.7	-0.3	1.8
Illnesses of father: None of the above (group 1)	1.3	1.6	3.8	0.8	-1.9	-1.6	-1.7	-1.5	-1.6	-1.8	-1.4	-1.8	-1.0	-1.4	-1.0	-1.8	-0.2	-0.2	-0.0	-0.1	-0.2	-0.7
Number of self-reported non-cancer illnesses	1.3	2.2	12.5	1.4	1.0	1.6	0.0	0.2	0.8	0.9	0.9	0.7	-1.0	0.8	3.5	0.6	2.2	1.4	1.7	2.0	1.3	1.9
Medication: Bendroflumethiazide	1.3	1.9	6.6	1.1	0.9	1.6	2.1	0.6	1.7	1.4	1.3	1.1	0.1	0.8	-0.5	1.3	0.6	2.1	1.8	1.0	1.3	2.6
Leg fat percentage (left)	1.3	4.8	9.1	2.4	2.1	3.0	2.2	2.0	3.0	3.0	2.4	2.4	0.4	2.1	2.6	1.9	1.5	1.6	1.3	2.1	2.5	1.3
Age started oral contraceptive pill	1.3	1.6	3.5	1.9	-1.4	-1.2	-0.9	-1.7	-1.3	-1.1	-1.2	-1.6	-1.7	-1.6	-0.4	-1.8	0.4	1.1	0.8	-0.2	0.9	0.4
Pack years of smoking	1.3	1.9	9.4	3.1	0.4	0.8	0.4	-0.7	0.5	0.6	0.7	-0.1	-1.0	0.5	-0.3	0.0	2.5	1.5	1.5	2.1	2.0	1.7
Ovarian Cancer	1.2	1.5	2.5	1.6	1.3	1.5	1.5	1.3	1.4	1.0	1.4	1.5	-0.1	1.5	0.7	1.2	1.1	-1.1	-1.4	1.5	-0.8	0.3
Waist circumference	1.2	4.4	9.3	2.6	2.3	3.0	1.9	1.8	2.9	2.6	2.3	2.1	1.3	2.0	3.1	1.8	1.8	0.7	0.4	2.4	1.4	1.0
Hair/balding pattern: Pattern 2	1.2	1.5	5.4	0.5	0.5	1.2	1.3	0.4	1.2	1.1	1.0	0.9	-1.0	0.9	-0.5	0.8	0.8	1.6	2.3	0.7	1.7	2.3
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	7.1	-0.4	1.6	1.8	1.6	2.5	1.6	1.8	2.1	2.4	1.5	2.7	-0.7	2.2	1.0	0.5	0.5	1.4	1.5	0.9
Illnesses of siblings	1.2	1.7	4.6	-0.6	-0.9	-2.1	-1.5	-1.1	-1.6	-1.8	-1.5	-1.7	0.7	-1.8	-1.7	-1.4	-0.5	-0.3	0.4	-1.5	0.2	-1.2
Worrier / anxious feelings	1.2	2.2	5.9	-2.4	-1.3	-1.8	-1.5	-1.4	-1.8	-1.9	-1.7	-1.4	-0.4	-1.7	-0.9	-1.3	-1.6	0.5	0.7	-2.1	0.1	-1.3
Mouth/teeth dental problems: Loose teeth	1.2	1.5	2.9	0.1	-1.0	-1.4	-1.5	-1.6	-1.5	-1.7	-1.5	-1.6	0.4	-1.7	-0.6	-1.6	-0.9	-0.6	-0.4	-1.6	-0.5	-0.5
Medication for pain relief, constipation, heartburn	1.2	2.0	10.4	-0.7	-0.4	-1.5	-0.6	-0.7	-0.8	-1.1	-1.4	-1.1	1.5	-1.4	-0.8	-0.8	-1.7	-1.9	-1.9	-1.7	-3.2	-0.7
Illnesses of father: High blood pressure	1.2	1.5	4.3	-0.2	-2.1	-1.6	-0.9	-2.0	-1.2	-1.2	-1.4	-1.5	-0.2	-2.0	-1.3	-1.5	-0.5	-0.4	-0.1	-1.1	0.2	-0.4
Myopia	1.2	1.8	9.5	-3.1	-0.4	-0.8	0.1	1.2	-0.7	-0.8	-0.2	0.3	2.2	0.4	-2.2	0.5	-2.3	-0.5	-0.6	-1.3	-1.2	-1.4
Blood Red Count	1.1	10.2	45.6	-1.6	2.4	3.0	2.9	3.8	1.0	-1.4	2.3	2.6	6.8	2.9	1.3	2.9	-1.1	-4.8	-4.8	1.7	-4.6	-1.7
Impedance of leg (right)	1.1	5.4	12.6	-0.4	-2.9	-3.5	-2.8	-2.9	-3.2	-2.0	-3.2	-2.8	-1.2	-2.9	-1.9	-3.0	-0.9	-0.0	0.4	-2.4	0.7	-2.1
Stomach or abdominal pain in last month	1.1	1.4	4.0	0.3	2.0	1.6	1.5	1.2	1.3	1.5	1.4	1.3	1.2	1.2	1.2	1.6	0.3	-0.7	-0.5	0.5	-0.3	0.5
Mouth/teeth dental problems	1.1	1.7	6.6	-2.6	-0.5	-0.8	-0.4	0.8	-0.5	-0.8	-0.4	0.0	1.9	0.0	-1.0	0.0	-2.2	-0.8	-1.2	-1.7	-1.1	-2.5
Medication: Omeprazole	1.1	1.3	4.9	1.0	1.1	1.5	0.8	1.4	0.7	1.3	1.0	1.1	0.9	1.4	2.2	0.6	1.4	-0.5	-0.1	1.4	1.1	-0.4
Ever taken oral contraceptive pill	1.1	1.3	2.9	0.5	1.2	1.6	1.1	1.3	1.5	1.0	1.4	1.5	1.7	1.1	0.7	1.5	0.8	0.1	0.1	0.8	1.1	0.0
Qualifications: CSEs or equivalent	1.0	1.3	2.7	0.5	1.5	1.2	1.2	0.6	1.5	1.5	1.1	1.2	-0.0	1.0	0.0	1.0	0.7	1.6	1.4	1.3	0.4	1.6
Hip circumference	1.0	4.3	9.9	1.3	2.0	2.9	2.2	2.2	3.1	2.6	2.7	2.5	0.8	2.4	2.5	2.3	0.9	1.2	0.4	1.8	1.6	1.1
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	4.3	0.3	1.5	1.5	0.7	0.9	1.5	1.6	1.5	1.2	-0.5	1.4	1.2	1.0	2.1	0.5	0.6	2.0	1.3	0.9
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	6.3	-0.2	-1.2	-1.4	-0.8	-0.7	-0.6	-0.7	-0.6	-0.8	-2.1	-1.0	-1.0	-0.8	0.2	1.0	1.5	-0.6	2.5	-0.7
Illnesses of mother	1.0	1.3	5.3	1.1	0.5	0.7	1.7	0.7	0.8	0.6	1.1	1.1	0.3	1.0	-0.9	0.9	1.2	1.2	1.2	1.6	2.3	0.8
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	3.9	0.5	-1.2	-1.7	-1.4	-1.1	-1.4	-1.4	-1.4	-1.7	0.6	-1.4	-1.0	-1.7	-0.9	-0.6	-0.4	-1.8	0.2	-2.0
Medication: Ibuprofen	1.0	1.2	6.6	-0.1	-1.1	-1.0	-0.4	-0.5	-0.3	-0.3	-0.3	-0.5	-2.1	-0.7	-1.1	-0.6	0.2	1.6	1.9	-0.5	2.6	-0.2
Number of full sisters	1.0	1.3	4.8	1.6	0.6	1.0	1.2	0.2	1.0	0.8	1.3	0.8	-1.4	1.1	1.5	0.8	1.6	0.3	-0.1	2.2	1.0	0.4
Chest pain or discomfort	1.0	1.5	5.1	1.0	1.1	0.8	1.4	1.2	1.1	1.1	1.3	1.2	-0.3	1.4	2.3	0.8	1.5	0.1	0.2	1.7	1.8	-0.5
Medication: Aspirin	1.0	1.4	4.4	0.3	0.9	2.1	1.1	1.1	1.2	1.0	1.6	1.6	0.8	1.6	-0.0	1.6	0.3	1.1	0.4	1.3	0.9	0.8
Hearing aid user	1.0	1.1	4.2	0.7	1.1	0.6	1.0	0.1	0.2	0.3	0.6	0.5	0.3	0.7	2.1	0.8	1.7	-1.3	-1.6	2.0	-0.9	-0.2
Medication: Atorvastatin	1.0	1.3	3.2	-1.1	0.5	1.3	0.7	1.4	1.0	0.9	1.1	1.2	1.0	1.6	0.8	1.2	0.3	-1.4	-1.8	1.1	-1.2	-0.4
Average weekly beer plus cider intake	1.0	1.4	8.3	1.2	-0.2	0.1	-0.2	0.2	-0.3	-0.4	0.2	-0.0	0.8	0.3	1.1	-0.2	1.4	-2.3	-2.9	1.5	-0.3	-2.2
Unable to work because of sickness or disability	1.0	1.3	7.2	0.8	1.0	1.2	0.6	0.5	1.0	0.7	0.8	0.8	1.2	0.6	2.7	0.8	0.7	-1.9	-1.7	0.6	-0.8	-0.3
Heart attack/myocardial infarction (self-reported)	1.0	1.3	2.6	0.6	-1.1	-1.2	-1.1	-1.3	-1.3	-0.2	-1.4	-1.2	-0.9	-1.4	1.3	-1.6	1.5	-0.9	-0.6	0.1	0.7	-1.3
Neuroticism (2016)	0.9	1.3	4.8	-2.2	-0.9	-0.8	-1.3	-0.0	-1.3	-1.8	-1.1	-0.7	1.7	-0.7	-0.7	-0.6	-1.3	0.5	0.3	-1.3	0.4	-1.4
Pack years adult smoking proportion	0.9	1.3	8.5	2.9	0.3	0.4	0.1	-0.7	0.2	0.4	0.4	-0.3	-0.9	0.2	-0.1	-0.2	2.3	0.9	1.1	1.9	1.6	1.3
Number of incorrect matches in round	0.9	1.5	3.3	-0.5	-1.0	-1.2	-1.5	-1.5	-1.2	-0.9	-1.8	-1.4	-0.7	-1.8	1.6	-1.8	-0.1	0.9	1.5	-1.1	-0.1	0.6
Heart attack	0.9	1.1	2.7	0.6	-1.0	-1.1	-1.1	-1.2	-1.2	-0.0	-1.3	-1.1	-0.8	-1.2	1.2	-1.5	1.6	-0.8	-0.7	0.2	0.8	-1.2
Fluid intelligence score	0.9	1.9	5.2	-1.0	-1.3	-1.5	-0.9	-0.4	-1.1	-1.4	-1.0	-1.2	1.1	-0.9	-2.3	-1.1	-1.9	-1.1	-1.6	-2.1	-1.0	-2.0
Depression (self-reported)	0.9	1.1	3.4	0.9	0.9	1.2	0.7	0.8	1.0	1.6	0.9	0.8	-1.0	0.9	1.9	0.7	1.3	0.3	0.5	1.4	0.9	1.0
Peak expiratory flow (PEF)	0.9	2.1	10.1	-2.6	-0.2	-1.4	-0.2	1.2	-0.6	-1.2	-0.8	-0.4	1.5	-0.4	-0.1	-0.5	-0.3	-2.6	-2.3	-0.7	-1.4	-3.2
Number of children fathered	0.9	1.0	4.0	-0.3	-0.6	-0.8	-1.0	-1.0	-0.9	-0.5	-0.8	-0.9	-0.8	-0.6	-0.5	-0.9	-0.7	1.6	2.0	-1.4	1.3	0.4
Heart disease (mother)	0.9	1.1	3.5	-1.7	0.8	0.5	-0.2	1.4	0.5	0.4	0.4	0.7	0.8	0.9	1.7	0.9	-1.9	0.3	-1.1	-0.9	-1.6	-0.8
Leg pain on walking	0.9	1.1	4.5	2.1	1.0	1.1	0.4	0.5	0.5	0.3	0.7	0.5	0.1	0.5	2.0	0.3	2.0	-0.9	-0.4	1.5	0.7	-0.5
Medication: Aspirin	0.9	1.2	3.9	0.5	0.7	2.0	0.8	0.9	1.3	1.2	1.4	1.4	0.6	1.4	0.3	1.3	0.7	1.2	0.6	1.3	1.1	1.0
Average weekly champagne plus white wine intake	0.9	1.3	4.2	-0.8	-1.5	-1.3	-1.0	-1.1	-1.4	-1.3	-1.0	-1.3	-0.7	-1.1	-2.0	-1.0	-0.8	1.1	0.7	-1.1	1.0	-0.5
Guilty feelings	0.9	1.4	5.1	-2.3	1.0	0.7	1.3	1.7	1.0	0.8	1.0	1.5	1.3	1.3	1.2	1.6	-0.7	0.3	0.4	-0.5	0.9	-0.7
Mother’s age at death	0.9	1.2	4.3	0.2	-1.3	-1.4	-1.5	-1.2	-1.2	-1.2	-0.9	-1.3	-2.1	-1.2	-0.8	-1.1	0.3	0.5	1.0	-0.2	0.7	-0.1
Pain experienced in last month	0.9	1.6	8.9	-0.7	-1.8	-1.7	-0.4	-1.1	-1.1	-0.7	-1.4	-1.2	-0.5	-1.2	-3.0	-0.8	-1.4	-0.2	-0.3	-1.5	-0.8	0.3
Bipolar Disorder or Schizophrenia	0.8	2.0	8.7	-0.2	-0.8	-1.4	-1.7	-1.3	-1.6	-1.5	-2.1	-1.7	1.0	-2.0	2.9	-2.0	0.1	-0.2	-0.2	-0.7	-0.1	-1.0
Rheumatoid Arthritis	0.8	1.2	2.7	1.6	-0.2	-1.0	-0.8	-1.5	-1.2	-0.8	-1.2	-1.2	-0.1	-1.3	0.3	-1.6	0.3	1.5	1.3	-0.8	1.2	0.3
Blood Platelet Count	0.8	9.6	48.7	-5.1	-1.9	-0.7	2.0	1.8	1.0	1.4	2.1	1.7	-6.2	1.7	-7.0	2.2	-2.9	3.3	2.4	-1.8	3.3	0.6
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	4.0	-0.9	0.0	-0.9	-0.4	-0.4	-1.2	-0.8	-1.0	-0.7	0.5	-0.4	0.7	-1.0	-0.0	-1.6	-1.2	0.1	-2.0	-1.2
Serious illness, injury or assault to yourself	0.8	1.0	11.1	1.2	0.3	0.7	-0.6	0.2	0.6	1.0	0.3	0.4	1.3	0.6	3.3	0.2	0.7	-0.4	-0.7	0.6	-0.2	-0.2
Medication: Simvastatin	0.8	1.2	4.9	0.1	0.9	1.5	0.9	0.9	0.9	0.9	0.9	1.1	-0.2	0.6	2.2	1.0	0.6	1.1	1.6	0.5	1.3	1.4
Tense / ‘highly strung’	0.8	1.3	4.7	-0.7	-1.1	-0.7	-0.8	-1.4	-0.9	-0.4	-0.4	-0.8	-2.2	-0.6	-1.6	-0.4	-0.1	1.8	1.9	-0.6	1.6	1.0
Medication: Paracetamol	0.8	1.3	5.0	0.4	0.7	1.1	0.8	0.3	0.6	0.8	1.0	0.6	-1.1	1.2	0.8	0.5	0.9	2.2	1.9	0.8	2.1	1.2
Number of full brothers	0.8	1.0	4.6	1.3	0.5	0.3	0.2	0.5	0.7	0.7	0.5	0.4	-0.4	0.5	1.2	0.1	1.6	1.4	1.6	1.3	2.1	0.1
Medication: Blood pressure	0.8	1.4	3.5	0.5	1.2	1.6	1.5	0.6	1.5	1.5	1.3	1.4	0.1	1.0	0.9	1.3	1.1	-0.2	-0.1	1.9	-0.5	1.7
Medication: Allopurinol	0.8	1.0	3.9	2.0	-0.8	-0.4	-0.1	-1.3	-0.3	-0.3	-0.4	-0.8	-1.0	-0.8	-1.2	-1.0	0.9	1.0	1.2	0.3	1.7	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	6.2	1.0	0.9	0.9	1.2	-0.2	1.1	0.8	1.0	0.6	-0.4	0.5	-0.6	0.8	1.0	0.6	0.8	1.4	0.4	2.5
Overall health rating	0.8	1.7	12.0	1.1	1.4	1.9	0.1	0.6	1.3	1.4	1.2	0.8	1.4	1.2	3.5	0.8	0.8	-0.7	-1.1	0.9	0.2	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.0	0.3	0.8	1.1	0.9	0.8	1.2	0.8	1.2	1.0	1.1	1.2	-0.8	1.3	0.9	-0.4	-1.1	1.4	-0.3	0.6
Knee pain experienced in last month	0.8	1.3	8.5	-0.0	1.0	0.9	0.7	1.3	0.5	0.0	0.7	0.8	2.5	0.8	2.9	0.4	0.7	-0.6	-1.0	-0.2	0.6	-1.3
Illnesses of siblings: Diabetes	0.8	0.9	5.8	0.7	0.8	1.3	0.4	1.1	1.0	0.7	0.8	0.7	1.0	0.8	2.4	0.6	0.9	-1.0	-1.1	0.8	-0.3	-0.0
Average weekly red wine intake	0.8	1.2	5.6	-2.4	-0.6	-1.2	-0.3	-0.4	-1.0	-1.1	-0.7	-0.6	-1.3	-0.7	-1.3	-0.3	-1.4	1.0	0.9	-1.2	-1.0	0.9
Loneliness, isolation	0.8	1.1	4.2	-0.5	1.4	1.2	1.0	1.7	1.3	0.6	1.2	1.3	0.5	1.2	2.1	1.4	-0.1	-0.1	0.3	0.3	0.2	0.2
Ever had bowel cancer screening	0.8	0.9	4.5	-2.1	-1.2	-0.1	-0.6	0.1	-0.9	-0.5	-0.8	-0.5	-0.1	-0.3	1.5	-0.6	-1.4	1.5	1.1	-1.2	0.3	-0.3
Commuting to job workplace: Walk	0.8	0.9	1.7	-0.0	1.3	1.0	0.5	1.3	1.0	1.1	0.7	1.2	1.2	0.8	1.3	1.0	1.0	-0.6	-1.0	1.1	-0.5	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	4.2	1.9	0.1	0.7	1.0	0.0	0.9	1.5	0.7	0.6	-1.6	0.4	0.0	0.3	2.0	0.2	0.3	1.9	1.0	1.7
Medication: Paracetamol	0.8	1.3	6.4	0.6	-0.2	0.5	0.3	-0.6	0.1	0.3	0.5	-0.1	-1.9	0.4	0.4	-0.1	0.7	2.5	2.2	0.3	2.2	1.5
Commuting to job workplace: Cycle	0.8	1.0	4.8	0.5	-0.6	0.1	0.7	-0.4	0.5	0.4	0.3	0.1	-1.5	-0.3	-1.1	0.1	0.5	1.4	1.7	0.1	1.8	2.2
Fasting Glucose	0.7	0.8	2.1	1.1	0.6	0.9	0.6	0.6	0.8	0.8	1.0	1.0	-1.2	0.8	1.2	1.0	0.9	0.4	0.0	1.5	0.7	0.2
Ever had hysterectomy (womb removed)	0.7	0.8	2.3	-0.1	-1.2	-0.9	-0.8	-1.1	-1.2	-0.5	-1.3	-1.3	-0.2	-0.8	1.5	-1.4	-0.1	0.5	0.5	-0.4	0.2	-0.3
Medication: Metformin	0.7	1.0	1.8	0.4	1.0	1.3	0.5	1.1	1.1	0.9	1.1	1.0	1.1	1.3	1.2	0.9	0.6	-0.9	-1.3	1.1	-0.8	0.2
Maternal smoking around birth	0.7	1.1	2.3	1.0	0.7	1.3	0.8	0.6	0.9	1.5	1.0	1.0	-0.5	1.0	1.3	0.7	1.5	0.6	0.5	1.5	1.5	0.6
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	3.5	-0.6	0.3	-0.1	0.2	0.8	0.0	-0.4	0.2	0.4	1.3	0.2	1.2	0.5	-0.5	-1.9	-1.6	-0.4	-1.5	-0.9
Sitting height	0.7	5.3	12.2	-3.5	-2.5	-3.0	-2.3	-1.3	-2.6	-2.7	-1.9	-1.7	-1.4	-1.3	-3.2	-1.6	-2.6	2.4	1.5	-2.9	1.5	-2.2
Hearing difficulty/problems with background noise	0.7	1.1	2.8	-1.0	-1.1	-1.6	-1.3	-1.3	-1.7	-1.0	-1.3	-1.1	-0.7	-0.8	-0.3	-1.0	-0.5	-0.1	-0.5	-0.8	-0.9	-1.4
Happiness	0.7	0.8	2.0	0.2	1.3	1.1	0.3	0.8	1.4	1.3	1.2	1.0	-0.8	0.9	0.3	0.9	0.2	0.7	1.0	0.4	0.6	1.1
Pulse wave Arterial Stiffness index	0.7	0.8	4.3	-2.1	0.6	0.6	0.2	0.9	0.6	0.3	0.4	0.8	0.6	0.9	1.0	0.6	-1.8	0.4	0.3	-1.2	-0.9	-0.3
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.0	-1.3	-1.2	-1.0	-1.2	-0.7	-1.1	-1.1	-0.7	-0.8	0.9	-0.9	-1.2	-0.7	-1.4	-0.7	-0.8	-1.5	-0.2	-1.7
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	5.0	-2.0	-0.7	-1.6	-1.2	-0.4	-1.0	-1.1	-0.9	-0.6	0.3	-1.1	-1.1	-0.4	-1.5	-1.4	-1.1	-1.7	-1.0	-2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.5	-1.2	0.7	0.4	1.0	1.7	0.5	0.2	0.6	1.0	1.0	0.9	1.3	1.0	-0.8	-1.7	-2.1	0.3	-1.8	-2.1
Irritability	0.7	1.3	5.9	0.8	0.3	0.7	0.7	-0.7	0.5	0.2	0.7	0.3	-1.6	0.4	-0.8	0.3	0.8	2.4	2.0	0.8	2.0	1.6
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	3.3	0.6	0.8	1.1	0.4	1.0	0.6	1.2	0.7	0.8	1.1	1.3	1.8	0.5	0.9	-0.2	0.0	0.8	1.2	-0.5
Basal cell carcinoma (self-reported)	0.7	0.8	2.0	0.1	1.2	0.6	1.1	1.4	1.0	1.1	0.7	1.2	0.4	0.9	0.7	1.0	0.9	0.1	0.6	0.5	1.4	0.7
Schizophrenia vs Biploar Disorder	0.6	0.8	1.7	-1.3	0.8	0.4	1.3	1.3	0.7	1.0	0.6	1.2	0.4	1.0	-0.8	0.9	0.4	0.0	0.0	1.1	-1.2	-0.0
Worry (Nagel 2018)	0.6	1.3	2.5	-1.2	-1.1	-1.4	-1.2	-1.2	-1.6	-1.3	-1.5	-1.1	-0.8	-1.5	0.7	-1.4	0.2	0.8	1.2	-0.8	1.3	-0.4
Prostate Cancer	0.6	0.9	10.6	0.4	-0.7	-0.5	-0.4	-0.6	-0.4	-0.9	-0.6	-0.6	0.2	-1.0	-3.2	-0.5	-0.6	0.1	0.3	-0.6	-0.1	0.6
Chronotype (morning person)	0.6	1.4	3.0	-1.1	-1.7	-1.4	-1.2	-1.1	-1.1	-1.2	-1.5	-1.3	-1.5	-1.5	-1.3	-1.2	-0.5	0.6	1.0	-0.8	0.3	0.9
Hearing difficulty/problems: Yes	0.6	0.9	2.3	0.3	1.1	0.8	0.6	1.0	0.9	1.1	1.0	1.1	0.9	1.3	1.5	1.0	0.2	-0.5	-0.9	0.8	-0.9	-0.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	2.1	-0.7	-1.0	-0.8	-1.4	-0.4	-0.9	-0.9	-0.9	-0.9	-0.3	-0.8	0.5	-0.9	-0.6	-0.7	-0.8	-0.9	-0.6	-1.3
Supplements: Zinc	0.6	0.6	3.5	1.3	0.6	-0.1	0.3	-0.4	0.0	0.1	0.0	-0.3	-0.7	-0.3	1.7	-0.3	1.9	-0.6	-0.0	1.2	0.1	0.5
Hand grip strength (right)	0.6	1.7	8.6	-1.9	-1.3	-1.3	-0.7	-0.8	-0.9	-0.8	-1.0	-0.7	-2.0	-1.1	-2.9	-0.5	-1.8	0.9	0.5	-1.6	-0.5	-0.1
Weight	0.6	3.0	6.4	0.8	1.7	2.4	1.7	2.0	2.5	2.0	2.3	2.1	0.3	2.1	2.0	1.9	1.0	1.3	0.8	1.6	1.9	0.7
Father’s age at death	0.6	0.8	2.3	-1.5	-0.0	-0.9	-0.6	0.2	-0.6	-0.7	-0.7	-0.5	0.5	-0.5	0.2	-0.1	-1.4	-1.0	-0.7	-1.5	-1.0	-1.4
Pulse rate	0.6	1.0	2.9	1.1	-0.9	-0.9	-0.7	-1.7	-0.8	-0.4	-1.0	-1.4	-1.5	-1.3	0.7	-1.4	0.2	0.5	0.7	-0.8	0.7	0.2
Medication: Cholesterol lowering	0.6	1.0	2.9	-1.7	0.6	1.2	1.0	1.3	1.0	0.7	1.2	1.4	-0.4	1.1	0.7	1.4	0.1	0.6	0.7	0.8	0.3	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	9.9	-2.4	-0.3	-1.1	-0.3	0.7	-0.8	-1.5	-0.5	-0.3	1.1	-0.3	-0.6	0.0	-1.7	-1.8	-1.6	-1.3	-1.3	-3.2
Standing height	0.6	5.7	15.3	-3.9	-2.5	-3.3	-3.0	-1.2	-2.7	-2.6	-2.2	-1.8	-0.7	-1.6	-2.3	-1.7	-2.9	0.8	0.2	-3.3	0.0	-3.4
Glaucoma (self-reported)	0.6	0.7	1.5	0.4	0.8	0.6	1.0	0.9	1.0	0.9	0.6	1.0	1.1	0.6	-0.5	0.7	-0.2	1.1	1.0	-0.0	1.2	0.8
Medication: Amlodipine	0.6	0.8	4.6	-0.4	-0.6	-0.5	-0.9	-0.8	-0.7	-0.9	-0.9	-0.7	0.5	-1.0	0.2	-0.8	-0.0	-1.4	-1.4	0.0	-2.2	-0.2
Pulse wave peak to peak time	0.6	0.8	3.7	1.9	-0.6	-0.6	-0.3	-0.8	-0.6	-0.4	-0.4	-0.8	-0.7	-0.9	-0.9	-0.6	1.7	-0.5	-0.2	1.0	1.1	0.1
Illnesses of father: Heart disease	0.6	0.8	4.5	-1.4	0.0	-0.8	-0.4	-0.5	-1.0	-0.9	-0.6	-0.6	0.4	-0.6	-0.6	-0.1	-1.8	0.2	-0.3	-2.1	-1.0	-0.7
Medication for cholesterol	0.6	0.9	5.6	-0.5	-0.7	-1.2	-0.1	-0.7	-0.7	-0.8	-0.6	-0.7	-0.8	-0.7	-2.4	-0.6	-1.0	-1.1	-0.5	-1.2	-1.1	0.1
Alcohol drinker status: Previous	0.6	0.6	2.3	-0.7	0.6	1.3	0.3	0.7	0.9	0.2	0.7	0.5	1.5	0.2	1.1	0.7	-0.7	-1.3	-0.6	-0.4	-0.9	0.3
Schizophrenia (2018)	0.5	1.0	10.5	-0.7	0.7	-0.2	-0.5	0.6	-0.3	-0.4	-0.8	-0.2	1.7	-0.2	3.2	-0.4	0.6	-0.9	-0.9	0.4	-0.9	-0.2
Irritable Bowel Disease (IBD)	0.5	1.2	5.2	1.0	-0.0	-0.5	-0.3	-0.9	-0.3	0.4	-1.0	-0.7	-1.1	-1.0	2.3	-1.0	1.1	1.2	1.8	-0.1	2.0	0.7
Crohns Disease (2012)	0.5	0.8	2.2	0.5	-0.2	-1.2	-0.7	-1.1	-0.7	-0.4	-1.3	-1.2	-0.7	-1.5	1.2	-1.4	0.5	0.4	0.7	-0.2	0.5	0.4
HDL Cholesterol	0.5	0.8	3.2	-1.3	0.2	-0.3	-0.2	0.8	-0.1	-0.2	-0.1	0.5	1.8	0.2	0.3	0.2	-1.8	-0.4	-1.3	-1.0	-0.7	-1.8
Lung FVC	0.5	2.8	7.8	-1.1	1.6	1.3	2.4	2.8	1.1	0.1	1.9	1.9	2.6	2.0	0.2	2.4	-1.7	-0.8	-1.6	0.4	-1.4	-1.1
Neuroticism	0.5	1.2	4.5	-1.4	-0.8	-0.7	-0.9	-0.8	-1.3	-0.9	-0.9	-0.7	-0.6	-0.7	-0.4	-0.8	-0.5	2.1	1.9	-0.8	1.9	-0.0
Hand grip strength (left)	0.5	1.2	7.1	-2.7	-0.9	-1.1	-0.4	-0.4	-0.8	-0.8	-0.7	-0.5	-1.6	-0.8	-1.9	-0.3	-1.4	0.5	0.2	-1.4	-0.8	-0.1
Average weekly spirits intake	0.5	0.6	1.6	-0.7	0.4	0.8	1.2	1.3	0.4	0.3	0.9	0.8	1.3	1.3	0.3	1.0	-0.8	0.1	-0.3	0.2	0.3	-1.0
Diabetes (mother)	0.5	0.7	3.6	-0.3	-0.4	-0.6	-0.9	-0.5	-0.7	-0.7	-0.8	-0.8	0.8	-0.6	-0.0	-0.8	-0.8	-0.9	-1.2	-0.5	-1.9	-0.7
Leg fat-free mass (left)	0.5	2.7	5.9	0.1	1.8	2.2	1.9	2.2	2.4	1.6	2.4	2.2	0.3	2.3	1.3	2.2	0.7	0.6	-0.0	1.7	0.6	0.7
High blood pressure	0.5	1.3	4.4	1.4	0.5	1.4	0.9	-0.4	1.3	1.2	0.6	0.5	0.1	0.0	1.9	0.4	1.4	1.5	1.4	1.2	1.1	2.1
Leg predicted mass (left)	0.5	2.8	6.0	0.0	1.7	2.3	1.9	2.2	2.4	1.6	2.4	2.2	0.4	2.4	1.3	2.2	0.6	0.5	-0.1	1.7	0.5	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.1	0.2	0.9	0.8	0.5	1.3	1.0	1.0	0.8	1.1	0.4	0.9	0.2	1.0	0.2	0.9	1.3	0.0	1.8	1.0
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	3.9	-0.6	0.6	0.5	0.3	1.1	1.0	0.9	0.7	0.9	0.4	0.7	2.0	0.7	0.7	0.1	0.2	0.8	0.6	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.9	-0.9	-0.2	0.8	-0.1	1.3	0.7	0.0	0.9	0.9	0.2	0.9	-1.4	1.0	-0.5	-0.2	-0.8	0.1	0.2	-0.9
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.3	-1.1	-1.1	-0.9	-0.8	-0.5	-0.8	-0.7	-1.0	-0.9	-0.9	-1.1	0.7	-0.7	-0.0	0.2	0.2	-0.8	0.5	-0.2
Blood clot in the leg (DVT)	0.5	0.7	4.3	-2.1	-0.1	0.6	-0.4	0.6	-0.0	-0.1	0.2	0.4	-0.2	0.5	1.7	0.5	-1.5	0.4	0.2	-0.6	-0.8	-0.7
Forced vital capacity (FVC), Best measure	0.5	1.7	7.5	-2.2	0.2	-0.8	0.0	1.0	-0.4	-1.2	0.1	0.2	1.0	0.2	-1.4	0.6	-1.8	-1.7	-1.7	-1.0	-1.8	-2.7
Health satisfaction	0.5	0.7	2.6	0.1	0.9	1.5	-0.4	0.8	0.5	-0.1	1.0	0.7	0.6	1.0	1.6	0.8	-0.4	-0.7	-0.6	0.0	0.0	-1.1
Angina (self-reported)	0.5	0.7	3.4	0.4	-0.7	-0.9	-0.6	-0.7	-0.5	0.0	-0.4	-0.7	-1.8	-0.5	0.5	-0.8	1.3	0.2	0.8	0.5	1.6	-0.5
Mean time to correctly identify matches	0.5	0.9	2.4	0.5	-1.3	-1.3	-1.5	-0.9	-1.2	-1.0	-1.2	-1.3	0.0	-1.3	-0.5	-1.2	-0.5	-0.4	-0.5	-0.7	-0.6	-0.4
Suffer from ‘nerves’	0.5	0.7	3.6	0.5	0.3	0.2	0.2	-0.5	0.1	0.4	0.1	0.1	-1.3	-0.1	0.6	0.0	0.9	1.5	1.8	0.2	1.9	1.0
Age at last live birth	0.5	0.7	2.6	-1.4	0.4	-0.5	0.5	1.1	0.3	0.2	0.2	0.6	0.1	0.4	-1.6	0.6	-1.0	-0.9	-1.1	-0.6	-1.0	-0.7
Hypertension (Self-reported)	0.5	1.5	4.2	1.7	0.5	1.5	1.0	-0.6	1.2	1.2	0.6	0.4	0.1	0.1	2.0	0.4	1.6	1.5	1.4	1.4	1.4	1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	2.2	-0.4	-0.4	-0.2	-0.9	-0.1	-0.8	-0.8	-0.7	-0.7	-0.7	-0.7	0.2	-0.9	0.0	0.9	1.5	-0.4	1.4	-0.5
Smoking status: Previous	0.5	0.7	2.5	-1.0	1.0	1.1	0.1	1.3	0.6	0.7	1.1	1.2	0.4	1.6	0.3	1.2	-0.3	0.8	0.4	0.0	0.6	-0.3
Eye problems/disorders: Cataract	0.5	0.6	2.1	1.4	-0.3	0.2	-0.8	-0.8	-0.2	0.3	-0.2	-0.4	-0.7	-0.4	1.0	-0.5	0.7	1.3	0.9	-0.3	1.0	0.9
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	3.2	-1.8	0.2	0.9	0.0	0.8	0.3	0.3	0.6	0.9	-0.3	0.9	1.8	0.7	-1.2	0.7	0.5	-0.3	-0.5	-0.3
Impedance of whole body	0.5	2.4	7.0	-0.8	-1.6	-2.5	-2.3	-1.4	-2.0	-1.0	-2.0	-1.5	-0.0	-1.5	-0.5	-1.7	-0.9	-0.4	-0.0	-1.8	0.5	-2.6
Crohns Disease (2017)	0.4	0.9	2.5	0.4	-0.5	-1.0	-0.8	-1.0	-0.7	-0.0	-1.0	-1.0	-1.5	-1.2	1.6	-1.0	1.2	0.7	1.0	0.1	1.3	0.4
Heel T-Score	0.4	3.0	6.7	1.8	1.4	2.4	1.7	2.2	1.5	1.5	2.2	1.9	2.6	2.4	1.3	2.0	1.5	-0.1	-0.6	1.5	1.2	0.1
Waist Hip Ratio (WHR)	0.4	2.0	7.3	2.7	-0.3	-1.0	-2.0	-1.9	-1.4	-0.8	-1.8	-1.9	0.6	-1.8	0.3	-2.0	1.5	-1.1	-0.6	0.4	-0.6	-0.9
Cardiovascular Disease	0.4	1.3	3.2	1.5	0.7	1.7	0.6	0.6	1.2	1.2	0.9	0.9	-0.0	0.4	1.7	0.9	1.8	0.6	0.7	1.8	1.0	1.5
Systolic blood pressure, automated reading	0.4	1.0	4.0	0.2	-0.9	0.0	0.1	-1.4	-0.2	0.3	-0.8	-0.6	-1.4	-0.8	0.9	-0.8	0.7	1.8	1.9	0.1	0.9	2.0
Angina	0.4	0.5	2.2	0.2	-0.5	-0.7	-0.6	-0.5	-0.5	0.0	-0.4	-0.5	-1.5	-0.3	0.5	-0.7	1.3	0.1	0.7	0.5	1.5	-0.5
Medication for hormone replacement therapy	0.4	0.5	2.1	-0.5	-0.5	-0.9	-0.4	-0.7	-0.4	-0.0	-0.7	-0.6	-0.6	-0.7	0.8	-0.7	0.1	1.1	0.7	-0.2	1.5	-0.6
Townsend deprivation index at recruitment	0.4	0.6	1.4	1.0	0.8	0.8	0.6	1.0	0.8	0.2	1.1	0.8	0.4	0.7	-0.1	0.9	0.7	-0.1	0.2	1.0	1.2	0.0
Medication: Atenolol	0.4	0.5	2.4	-0.6	0.7	0.9	0.2	1.2	0.8	0.7	0.6	0.7	1.6	0.7	-0.0	1.0	0.1	0.1	0.1	-0.2	1.0	-0.3
Diabetes (self-reported)	0.4	0.6	2.7	0.4	0.6	0.5	-0.2	0.3	0.3	-0.1	0.1	-0.0	0.8	0.1	1.3	-0.1	0.2	-1.6	-1.6	0.3	-1.6	-1.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	7.5	-2.2	-0.0	-1.0	0.3	0.9	-0.5	-1.4	-0.3	-0.1	1.3	-0.2	-0.6	0.1	-1.2	-1.7	-1.5	-0.8	-1.3	-2.7
Length of working week for main job	0.4	0.4	1.3	-1.0	0.7	0.6	0.4	1.2	0.6	0.1	0.8	0.7	0.8	1.1	0.1	0.8	-0.6	0.1	-0.1	0.3	-0.6	0.3
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.7	0.8	-0.0	0.5	-0.5	-0.2	0.2	0.3	0.1	-0.2	-0.7	0.0	-0.3	-0.1	0.3	1.3	1.2	-0.0	0.9	1.6
Eye problems/disorders: None of the above	0.4	0.4	2.0	-1.0	-0.3	-0.9	-0.1	-0.1	-0.7	-1.0	-0.6	-0.5	-0.3	-0.4	-1.4	-0.4	-0.2	-0.3	0.5	-0.1	0.6	-1.0
Family relationship satisfaction	0.4	0.5	2.4	-0.4	0.6	0.7	0.0	0.8	0.7	0.4	0.7	0.6	-0.3	0.8	0.7	0.4	0.2	0.6	0.9	0.3	1.5	-0.7
Leg fat-free mass (right)	0.4	2.2	4.9	-0.5	1.6	2.0	1.7	2.1	2.1	1.3	2.2	2.0	0.5	2.2	1.0	2.1	0.3	0.6	-0.2	1.3	0.3	0.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.7	0.8	-0.6	-1.1	0.3	-0.7	-0.5	-0.4	-0.7	-0.5	-1.3	-0.8	-0.9	-0.7	0.3	0.4	0.5	-0.2	1.0	0.2
Diabetes diagnosed by doctor	0.4	0.6	1.9	0.9	0.9	0.9	0.1	0.3	0.5	0.5	0.5	0.2	0.0	0.5	1.3	0.1	1.1	-1.4	-1.2	1.0	-1.1	-0.4
Leg predicted mass (right)	0.4	1.9	4.4	-0.5	1.4	1.9	1.6	2.0	2.0	1.2	2.1	1.9	0.4	2.1	1.0	1.9	0.2	0.6	-0.1	1.2	0.3	0.4
Miserableness	0.4	0.7	2.7	0.5	-0.5	-0.5	-0.6	-1.4	-1.0	-0.7	-0.6	-0.9	-1.6	-0.9	-0.0	-1.0	0.3	1.3	1.2	-0.2	1.0	-0.0
Wears glasses or contact lenses	0.4	0.5	3.5	-1.9	-0.0	-0.5	-0.4	0.6	-0.4	0.1	-0.2	0.1	0.1	0.1	-0.1	0.2	-1.2	-0.5	-0.7	-0.8	-1.3	-0.1
Eye problems/disorders: Glaucoma	0.4	0.5	1.4	0.5	0.8	0.7	0.5	0.7	1.0	1.2	0.6	1.0	0.9	0.7	-0.3	0.6	0.1	0.5	0.3	0.5	0.4	0.8
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.4	-1.3	-0.1	-0.8	-0.3	0.7	-0.5	-0.7	-0.1	0.0	0.7	0.3	-1.5	0.1	-1.8	-1.7	-1.7	-1.2	-1.7	-1.8
Depressed Affect (Nagel 2018)	0.3	0.7	1.9	0.0	1.3	0.9	0.8	0.9	1.1	0.9	0.9	1.0	0.1	1.0	1.4	0.5	0.5	0.9	0.7	0.4	1.0	0.5
Ulcerative Colitis (UC)	0.3	0.5	2.5	0.8	0.2	-0.1	-0.3	-0.6	-0.0	0.4	-0.9	-0.3	-0.1	-0.6	1.6	-0.8	0.2	0.6	1.2	-0.6	1.2	0.2
Reaction Time	0.3	0.6	1.6	0.4	-1.1	-1.2	-1.3	-0.9	-0.9	-0.7	-1.0	-1.0	-0.1	-1.1	-0.8	-1.1	-0.3	-0.3	-0.2	-0.4	-0.4	-0.4
Breast Cancer	0.3	0.6	1.7	0.3	-0.9	-0.7	-0.2	-0.7	-0.1	0.4	-1.2	-1.0	-1.3	-1.2	-0.0	-1.1	-0.7	0.2	0.7	-1.3	0.7	-0.6
Schizophrenia (2014)	0.3	0.8	6.5	0.1	-0.0	-0.4	-0.5	-0.3	-0.8	-1.0	-1.1	-0.8	0.9	-0.7	2.6	-1.1	0.8	-0.4	-0.5	0.5	-0.4	-0.1
Height	0.3	5.7	20.3	-4.2	-2.1	-3.5	-2.8	-0.8	-2.7	-2.6	-2.2	-1.5	-1.5	-1.3	-1.5	-1.7	-2.3	0.1	-0.2	-3.1	0.1	-4.5
Systolic Blood Pressure	0.3	1.5	4.3	-0.7	-1.8	-1.4	-1.3	-1.8	-1.3	-0.7	-2.1	-1.5	-1.3	-2.0	-0.3	-1.6	0.4	0.3	0.2	-0.4	-0.2	0.1
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.0	1.3	0.1	0.5	-0.2	-0.3	0.0	0.1	-0.0	-0.5	-0.9	-0.0	1.4	-0.5	1.4	-0.9	-0.9	1.2	-1.1	0.3
Severe depression (siblings)	0.3	0.4	1.4	-0.3	0.6	0.6	1.2	0.6	0.9	0.7	0.7	0.8	0.5	0.6	-0.4	0.6	-0.4	0.3	0.4	-0.0	0.1	1.0
Fed-up feelings	0.3	0.5	1.7	0.7	0.8	0.6	0.9	0.4	1.1	1.0	0.8	0.6	-0.1	0.6	0.4	0.6	0.3	0.9	0.8	0.2	1.3	0.3
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.9	-0.8	1.3	0.5	0.5	1.2	1.2	0.9	0.9	1.0	0.3	0.7	1.4	1.1	0.0	-0.3	0.3	0.2	0.0	-0.3
Nervous feelings	0.3	0.6	2.3	-0.0	-0.7	-0.7	-0.5	-0.9	-0.9	-0.7	-0.9	-0.6	-0.1	-1.1	0.2	-0.6	0.5	0.5	1.2	-0.4	1.5	-0.4
Had menopause	0.3	0.3	1.9	1.3	0.3	0.7	0.4	0.2	0.4	0.4	0.3	0.2	1.1	0.3	1.4	0.1	0.3	-0.1	-0.2	0.3	0.1	0.5
Forced vital capacity (FVC)	0.3	1.0	3.2	-1.8	0.8	-0.2	1.0	1.6	0.3	-0.8	0.8	0.9	0.9	0.8	-0.9	1.1	-1.3	-0.6	-0.8	-0.3	-1.2	-1.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.4	0.2	1.1	0.6	-0.1	0.8	0.8	0.2	0.5	0.4	0.6	-0.0	0.4	0.4	0.4	-1.2	-1.1	0.2	-0.7	-0.5
Pain all over the body in last month	0.3	0.3	1.1	1.1	-0.2	-0.3	-0.9	-0.3	-0.5	-0.4	-0.2	-0.3	-0.5	-0.1	-0.5	-0.5	0.8	-0.1	-0.8	0.9	-0.1	-0.4
Neuroticism score	0.3	0.6	2.1	-0.8	-0.5	-0.7	-0.6	-0.9	-0.8	-0.5	-0.6	-0.4	-0.7	-0.6	-0.1	-0.5	-0.2	1.2	1.3	-0.8	1.5	-0.3
Falls in the last year	0.3	0.4	2.3	0.9	0.9	0.2	-0.4	0.3	0.4	0.3	0.4	0.1	1.1	0.4	1.5	0.3	0.0	-1.0	-0.9	-0.0	-0.5	-0.2
Exposure to tobacco smoke at home	0.3	0.3	2.1	1.4	0.3	0.5	0.5	-0.1	0.5	0.8	0.4	0.6	-0.3	0.2	-0.2	0.4	0.2	-0.7	-0.6	0.8	0.1	-0.5
Pulse wave reflection index	0.3	0.3	1.9	-1.4	-0.1	0.2	0.1	0.2	0.3	0.3	0.1	0.6	-0.2	0.3	-0.9	0.3	-0.9	0.4	-0.1	-0.2	-1.1	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.3	0.6	0.6	0.5	-0.5	0.3	0.6	1.0	0.1	0.4	0.3	0.2	1.5	0.2	0.6	0.8	0.4	0.6	0.6	0.5
Neck or shoulder pain in last month	0.3	0.4	2.7	0.2	1.0	0.9	0.3	0.6	0.6	0.1	0.7	0.5	0.2	0.3	1.6	0.5	-0.4	0.0	0.2	-0.5	0.5	-0.9
Pulse rate, automated reading	0.3	1.0	6.2	2.5	0.3	0.1	0.9	-1.0	0.2	0.2	-0.1	-0.8	-1.4	-0.4	2.3	-0.8	0.8	0.5	1.0	0.1	0.7	0.8
Supplements: Vitamin C	0.3	0.4	3.0	1.7	0.6	0.4	0.5	-0.4	0.4	0.5	0.4	0.2	-0.2	0.3	-0.2	0.2	0.8	1.0	0.2	0.8	0.5	0.2
Commuting to job workplace: Public transport	0.3	0.4	2.6	-0.5	0.0	0.3	-0.0	0.4	-0.3	-0.5	-0.1	-0.1	1.5	0.1	-0.4	0.2	-1.6	-0.0	-0.4	-1.0	-0.7	-0.6
Risk taking	0.3	0.4	1.7	0.8	-0.3	0.5	0.2	0.2	0.5	0.5	0.8	0.6	-1.3	0.8	0.4	0.4	0.3	1.0	0.3	1.0	0.4	0.9
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.5	-0.9	0.2	0.2	-0.1	0.6	0.3	0.1	0.2	0.4	-0.8	0.2	-0.1	0.4	-0.5	0.4	1.2	-0.3	0.2	1.2
Diastolic blood pressure, automated reading	0.3	1.0	4.4	0.3	-0.9	-0.0	0.6	-1.4	0.1	0.1	-0.5	-0.5	-1.2	-0.9	0.6	-0.7	0.1	1.7	1.8	-0.5	1.0	2.1
Ever depressed for a whole week	0.3	0.4	1.9	0.2	0.2	-0.3	-0.9	-0.4	0.2	0.0	-0.7	-0.7	-0.1	-1.1	-0.5	-0.8	-0.1	-0.4	-0.7	-0.6	-1.4	0.2
Neuroticism (Nagel 2018)	0.2	0.4	2.0	-1.4	0.1	-0.2	-0.1	0.1	-0.3	-0.4	-0.2	0.2	0.1	-0.1	0.8	-0.2	-0.0	1.0	0.9	-0.4	1.3	-0.5
Major Depression (MDD)	0.2	0.3	1.8	-0.1	-0.0	-0.4	-0.7	-0.6	-0.2	0.1	-0.7	-0.2	0.6	-0.5	1.3	-0.7	0.2	0.0	0.0	0.2	-0.3	-0.4
Age at First Birth	0.2	0.3	0.9	-0.3	-0.4	-1.0	-0.6	0.2	-0.4	-0.3	-0.9	-0.4	-0.1	-0.7	0.9	-0.7	-0.6	-0.5	0.0	-0.7	-0.5	-0.8
LDL Cholesterol	0.2	0.3	3.2	-0.8	-0.1	0.2	-0.3	-0.6	-0.1	0.0	-0.2	-0.3	-0.3	-0.2	-1.8	0.0	-0.9	0.1	-0.4	-0.4	-0.7	-0.1
Ulcerative Colitis	0.2	0.3	1.9	0.2	0.8	0.3	0.5	-0.2	0.3	0.0	-0.2	0.0	1.1	-0.0	1.4	-0.1	-0.5	-0.3	0.2	-0.6	0.1	0.3
Allergy or Eczema	0.2	0.6	1.8	-1.0	0.7	0.4	0.6	1.2	1.1	0.7	0.7	0.9	0.4	0.5	1.4	0.9	-0.4	0.3	0.8	0.3	0.9	-0.0
Tanning	0.2	2.6	5.0	-2.0	-2.2	-2.0	-1.3	-1.2	-1.9	-2.1	-1.7	-1.8	-0.2	-1.7	-2.0	-1.6	-1.9	-0.0	-0.2	-2.1	-0.4	-0.9
High blood pressure (mother)	0.2	0.3	1.5	0.6	-0.1	0.3	-0.3	-0.7	0.2	0.3	-0.1	0.0	0.4	-0.4	0.5	-0.2	0.2	-1.2	-1.1	0.0	-1.2	-0.1
Medication: Ramipril	0.2	0.3	0.9	0.1	0.2	0.4	0.1	-0.2	0.3	0.5	0.1	0.4	-0.5	0.1	0.9	0.2	0.9	0.9	0.7	0.9	0.4	0.9
Number of live births	0.2	0.4	1.8	1.2	-0.1	0.0	-0.7	-1.3	-0.3	0.0	-0.1	-0.6	-1.0	-0.5	0.2	-0.2	0.6	0.4	0.4	0.1	0.2	0.7
Breastfed as a baby	0.2	0.3	2.3	0.7	-0.2	-0.1	-0.3	0.1	-0.1	-0.5	0.4	-0.1	-0.4	0.5	-1.5	0.0	0.5	0.3	-0.3	0.6	0.4	0.6
Hair/balding pattern: Pattern 4	0.2	0.5	1.2	0.4	0.1	-0.9	-0.8	-0.7	-0.6	-0.4	-0.7	-0.6	1.0	-0.6	-1.1	-0.3	-0.3	-0.5	-0.7	-0.6	-1.0	-0.4
Birth weight	0.2	0.4	2.1	-1.4	-0.3	-0.2	-0.4	-0.3	-0.4	-0.7	-0.3	-0.4	0.0	-0.5	-0.0	-0.4	-0.9	-0.6	-0.7	-0.6	-0.9	-1.1
Comparative body size at age 10	0.2	0.6	2.2	-0.1	0.5	0.7	1.1	0.8	0.6	-0.1	0.3	0.5	1.5	0.4	0.6	0.3	-0.1	-1.4	-1.1	0.3	-1.1	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.0	-0.6	-0.4	-0.5	-0.2	-0.1	-0.3	-0.1	-0.1	0.0	-0.9	-0.2	-1.0	-0.0	-0.4	0.1	-0.8	-0.0	-0.6	-0.2
Osteoporosis (self-reported)	0.2	0.3	0.8	-0.8	0.7	0.3	0.9	0.4	0.2	0.4	0.3	0.3	-0.4	0.6	-0.1	0.4	0.2	0.4	0.6	0.6	-0.7	0.9
Medication: Blood pressure	0.2	0.4	2.1	0.0	-0.2	0.5	-0.2	0.0	0.2	-0.1	-0.1	-0.2	1.3	-0.2	0.6	-0.1	-0.0	1.4	0.9	-0.2	1.5	-0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.3	-0.9	0.1	0.3	-0.2	-0.0	-0.2	-0.2	0.3	0.2	0.4	0.4	0.5	0.5	-0.1	0.4	-0.3	-0.6	1.1	-0.8
Heart disease (siblings)	0.2	0.3	2.5	0.1	-0.2	0.4	0.2	-0.3	-0.0	0.4	0.2	0.2	-1.6	0.6	-0.1	0.1	-0.3	0.5	0.0	0.5	-0.9	0.4
Alzheimer’s Disease (in father)	0.1	0.1	0.8	0.4	0.1	0.3	-0.5	0.3	0.0	0.9	-0.2	0.1	-0.1	0.1	0.3	-0.0	0.1	0.1	-0.0	0.1	-0.3	0.2
Triglycerides	0.1	0.2	1.7	0.1	0.1	0.0	0.6	-0.1	0.2	0.1	0.3	0.1	-1.3	0.2	-0.6	0.1	1.0	-0.1	0.2	0.4	0.2	0.7
Hypothyroidism (self reported)	0.1	0.2	1.7	-0.2	-0.0	0.3	0.1	0.2	-0.1	0.0	0.3	0.4	-1.3	0.5	0.2	0.5	0.1	0.5	0.5	0.4	0.2	1.0
Sensitivity / hurt feelings	0.1	0.2	0.8	-0.4	0.0	-0.1	-0.0	-0.4	-0.3	-0.2	-0.0	0.0	-0.5	-0.3	-0.6	0.2	-0.9	0.7	0.9	-0.8	0.2	-0.0
Medication: Levothyroxine sodium	0.1	0.2	1.4	-0.6	-0.2	0.2	-0.5	-0.1	-0.5	-0.3	-0.3	-0.1	0.4	0.1	0.8	-0.0	-0.3	-0.6	-0.9	-0.0	-1.2	-0.3
Impedance of arm (right)	0.1	0.5	2.7	-0.3	-0.6	-1.1	-1.4	-0.4	-0.7	-0.1	-0.7	-0.3	1.0	-0.3	-0.1	-0.6	-0.3	-0.6	-0.3	-0.6	0.2	-1.6
Hair/balding pattern: Pattern 3	0.1	0.1	0.6	-0.5	-0.2	0.4	-0.2	0.1	-0.1	-0.8	0.1	-0.0	-0.4	-0.0	0.1	0.1	-0.4	0.4	0.1	0.3	0.1	-0.2
Impedance of arm (left)	0.1	0.3	1.9	-0.3	0.1	-0.6	-0.7	0.2	-0.2	0.4	-0.1	0.3	0.8	0.3	0.5	-0.0	-0.0	-0.3	0.1	-0.3	0.6	-1.4
Arm fat-free mass (right)	0.1	0.3	0.6	-0.6	0.4	0.6	0.6	0.8	0.7	0.2	0.7	0.5	-0.8	0.7	0.7	0.5	-0.0	0.8	0.3	0.2	0.3	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.7	-0.3	-0.1	-0.2	0.0	-0.3	-0.2	-0.6	-0.2	-0.1	-0.5	-0.3	0.2	-0.2	0.0	0.7	0.9	-0.0	0.3	0.4
Medication: Seretide 50 evohaler	0.1	0.2	0.6	-0.2	0.1	0.8	0.1	0.3	-0.1	0.2	0.4	0.5	0.3	0.8	-0.3	0.5	0.2	0.3	0.2	0.1	0.1	0.7
Arm predicted mass (right)	0.1	0.5	1.3	-1.1	0.5	0.7	0.7	1.1	0.8	0.2	0.8	0.7	-0.4	0.9	0.5	0.8	-0.4	0.8	0.2	0.1	0.2	0.1
Comparative height size at age 10	0.1	0.3	2.2	-0.9	-1.1	0.1	-0.8	0.3	-0.0	-0.3	0.2	0.1	0.2	0.3	-0.2	0.1	-0.5	0.4	0.5	-0.5	1.5	-0.6
Whole body fat-free mass	0.1	0.4	1.1	-1.0	0.4	0.8	0.6	1.0	0.9	0.2	1.0	0.8	-0.3	1.0	0.2	0.9	-0.3	0.7	-0.0	0.3	0.1	0.3
Whole body water mass	0.1	0.4	1.0	-1.0	0.4	0.8	0.6	1.0	0.9	0.2	1.0	0.8	-0.3	1.0	0.3	0.9	-0.2	0.8	0.0	0.3	0.1	0.3
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	-0.2	-0.0	0.2	0.0	0.2	-0.0	-0.4	0.2	0.4	0.1	0.3	0.4	0.1	-0.1	0.6	0.3	0.6	-0.2	0.6
Basal metabolic rate	0.1	0.7	1.6	-0.5	0.6	1.1	0.8	1.0	1.2	0.6	1.2	1.0	-0.4	1.2	0.5	1.1	0.1	1.0	0.3	0.6	0.7	0.5
Arm fat-free mass (left)	0.1	0.3	1.2	-1.0	-0.6	-0.2	-0.4	-0.1	-0.2	-0.6	-0.2	-0.4	-0.9	-0.2	-0.2	-0.3	-0.7	1.1	0.3	-0.6	0.3	-0.1
Fractured/broken bones in last 5 years	0.1	0.2	1.1	0.6	0.0	0.0	-0.0	-0.4	-0.3	-0.4	-0.1	-0.1	0.6	-0.0	0.6	-0.2	-0.4	-0.3	-0.3	0.4	-1.0	0.5
Supplements: Calcium	0.1	0.1	0.5	-0.7	0.2	-0.3	-0.1	-0.3	-0.1	0.1	-0.2	-0.2	-0.6	-0.6	-0.0	0.2	-0.1	-0.6	-0.1	-0.4	-0.7	0.4
Hair Pigment	0.0	0.2	0.9	0.6	-0.3	-0.0	0.2	-0.6	-0.3	-0.1	-0.1	-0.3	0.2	-0.2	0.0	-0.2	0.4	-0.1	0.0	-0.5	0.7	-1.0
Trunk fat-free mass	0.0	0.3	1.9	-1.4	-0.4	-0.1	-0.1	0.1	0.0	-0.5	0.1	-0.0	-0.9	0.2	-0.6	0.1	-0.6	0.9	0.1	-0.2	-0.1	0.3
Trunk predicted mass	0.0	0.3	2.3	-1.5	-0.4	-0.2	-0.2	0.1	-0.1	-0.6	0.1	-0.1	-0.9	0.1	-0.6	0.1	-0.7	0.8	0.1	-0.3	-0.1	0.2
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.5	-0.3	-0.1	0.2	-0.4	-0.2	-0.6	-0.4	-0.1	-0.2	-0.3	0.1	-0.0	-0.0	0.1	-0.4	-0.2	0.1	-0.7	0.3
Arm predicted mass (left)	0.0	0.2	0.9	-0.8	-0.4	-0.0	-0.3	-0.1	-0.0	-0.4	-0.1	-0.2	-0.6	-0.1	0.2	-0.2	-0.5	0.9	0.2	-0.5	0.4	-0.1

Hub : Genes

RRP7B

Models

Trait associations