TWAS hub - CMTM5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0358	0.0133	0.0013	0.013	0.010	0.015	0.027	0.012	2.3e-05	0.0003	8.6e-06	3e-09	6.4e-05
2	TCGA	Testicular Germ Cell Tumors	0.1470	0.0690	0.0041	0.055	0.034	0.003	NA	0.047	5.1e-03	0.0230	2.4e-01	NA	9.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pulse rate, automated reading	36.7	118.5	234.1	-1.7	-15.3
Pulse rate	27.4	46.3	90.8	-1.3	-9.5
Pulse wave reflection index	5.1	6.3	12.2	-0.6	3.5
Angina (self-reported)	5.1	6.7	11.3	1.5	-3.4
Angina	4.7	6.2	10.5	1.4	-3.2
Shortness of breath walking on level ground	4.2	5.0	7.2	1.7	-2.7
Ever unenthusiastic/disinterested for a whole week	4.0	4.8	7.0	2.6	1.6
Serious illness, injury or assault of a close relative in last 2 years	3.7	4.2	7.8	0.8	2.8
Chronic bronchitis/emphysema (father)	3.3	3.9	4.9	1.7	-2.2
Emphysema/chronic bronchitis	3.3	3.7	4.7	1.7	-2.2
Financial situation satisfaction	3.0	3.7	6.9	-0.8	-2.6
Serious illness, injury or assault to yourself	2.8	3.4	6.0	2.4	0.9
Medication: Seretide 50 evohaler	2.8	3.2	4.0	1.6	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.8	3.3	3.9	2.0	-1.6
Medication for pain relief, constipation, heartburn	2.7	4.6	7.0	-2.6	1.5
Ever used hormone-replacement therapy (HRT)	2.6	3.3	6.4	2.5	-0.5
Loud music exposure frequency	2.5	2.7	5.1	-0.6	2.3
Supplements: Calcium	2.5	2.8	4.8	-0.8	2.2
Exposure to tobacco smoke outside home	2.4	3.2	4.4	1.4	-2.1
Qualifications: O levels/GCSEs or equivalent	2.3	3.7	7.4	0.2	-2.7
Alzheimer’s Disease (in father)	2.2	2.4	3.5	1.9	1.1
Length of working week for main job	2.2	2.5	4.6	-2.1	0.6
Medication: Metformin	2.1	2.9	5.7	-0.4	-2.4
Neck or shoulder pain in last month	2.1	2.9	5.9	-0.1	-2.4
Schizophrenia vs Biploar Disorder	2.0	2.6	4.7	-0.7	2.2
Exposure to tobacco smoke at home	2.0	2.2	2.3	1.5	-1.5
Commuting to job workplace: Car/motor vehicle	2.0	2.2	4.3	0.4	-2.1
Systolic blood pressure, automated reading	1.9	5.4	10.6	-0.5	3.3
Tense / ‘highly strung’	1.9	3.1	6.1	-0.3	-2.5
Headache pain in last month	1.9	3.3	3.3	1.8	-1.8
Current tobacco smoking	1.8	2.9	5.8	0.3	-2.4
Prostate Cancer	1.7	2.4	4.8	-0.3	-2.2
Maternal smoking around birth	1.7	2.5	2.7	1.7	-1.5
Medication: Amlodipine	1.7	2.4	3.2	1.8	-1.2
Chest pain or discomfort	1.7	2.4	4.9	0.0	-2.2
Number of operations (self-reported)	1.7	2.5	5.1	-0.1	-2.3
Ovarian Cancer	1.6	2.2	4.3	0.0	2.1
Supplements: Zinc	1.6	1.8	3.2	-1.8	0.6
Health satisfaction	1.6	2.0	2.6	1.2	-1.6
Medication: Omeprazole	1.6	1.9	3.4	1.8	-0.6
Fractured/broken bones in last 5 years	1.6	2.1	4.2	0.3	2.0
Primary Biliary Cirrhosis	1.5	2.1	2.6	-1.6	-1.3
Medication for hormone replacement therapy	1.5	1.6	2.9	1.7	0.6
Medication: Co-codamol	1.5	1.7	3.1	1.8	-0.6
Chronic bronchitis/emphysema (mother)	1.5	1.8	2.6	1.0	-1.6
Medication: Ibuprofen	1.5	1.8	3.1	1.7	0.7
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	3.2	-0.7	-1.8
Smoking status: Previous	1.5	2.3	3.4	1.1	1.8
Breast cancer (self-reported)	1.5	1.8	2.7	1.0	-1.6
Heart disease (siblings)	1.5	1.8	3.4	-0.4	1.8
Impedance of arm (right)	1.4	6.6	13.1	-0.2	-3.6
Impedance of arm (left)	1.4	6.3	12.3	-0.5	-3.5
Smoking status: Current	1.4	2.3	4.6	0.1	-2.1
Pack years adult smoking proportion	1.3	2.0	3.3	1.8	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	3.0	-0.6	1.7
Arm fat-free mass (right)	1.3	6.8	13.5	0.3	3.7
Myopia	1.3	1.9	3.7	0.2	1.9
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	3.2	1.8	-0.1
Pack years of smoking	1.3	2.0	3.4	1.8	-0.7
Impedance of whole body	1.3	6.4	12.6	0.4	-3.5
Bipolar Disorder (2018)	1.2	1.8	3.5	-1.9	-0.4
Alzheimer’s Disease (including proxy)	1.2	1.8	3.6	0.2	1.9
Systolic Blood Pressure	1.2	6.2	11.9	0.7	3.5
Qualifications: CSEs or equivalent	1.2	1.6	2.9	0.6	-1.7
Multivitamins +/- minerals	1.2	1.5	2.9	0.2	1.7
Supplements: Glucosamine	1.2	1.5	2.4	-1.6	0.8
Sitting height	1.2	8.6	17.1	-0.3	4.1
Arm predicted mass (right)	1.2	6.3	12.4	0.3	3.5
Alcohol intake frequency.	1.2	2.9	5.5	0.4	-2.3
Commuting to job workplace: Walk	1.2	1.3	1.6	1.0	1.3
Arm fat-free mass (left)	1.2	6.1	11.8	0.6	3.4
Ever had prostate specific antigen (PSA) test	1.2	1.4	1.6	1.1	1.3
Arm predicted mass (left)	1.2	6.3	12.2	0.7	3.5
Age at First Birth	1.1	1.6	1.9	-1.4	1.2
Vitamin and mineral supplements	1.1	1.5	3.0	-0.3	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.7	6.2	1.1	2.5
Glaucoma (self-reported)	1.1	1.4	2.7	0.1	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	2.4	-0.6	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.3	-1.5	-0.5
Had major operations	1.1	1.3	1.5	1.0	-1.2
Miserableness	1.1	2.0	3.1	-1.8	0.9
Lung FEV1/FVC ratio	1.0	4.9	6.5	1.8	2.6
Hearing difficulty/problems: Yes	1.0	1.5	1.6	-1.3	1.2
Past tobacco smoking	1.0	1.8	2.4	-1.1	-1.6
Nervous feelings	1.0	1.9	3.8	0.0	-1.9
Pain all over the body in last month	1.0	1.1	1.8	-0.6	1.4
Trunk fat-free mass	1.0	5.8	11.4	0.6	3.4
Asthma	1.0	1.9	3.7	0.4	-1.9
Trunk predicted mass	1.0	5.7	11.2	0.6	3.3
Birth weight	1.0	2.1	3.7	-1.9	0.6
Medication: Gliclazide	1.0	1.2	2.2	-0.3	-1.5
Whole body water mass	1.0	5.4	10.8	0.3	3.3
Average weekly champagne plus white wine intake	1.0	1.3	1.6	-1.3	1.0
Ever had hysterectomy (womb removed)	0.9	1.1	1.5	0.8	-1.2
Happiness	0.9	1.1	1.6	0.7	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	2.3	1.5	0.1
Ever highly irritable/argumentative for 2 days	0.9	1.0	1.5	1.2	-0.7
Medication: Paracetamol	0.9	1.5	1.8	1.3	-1.1
Mouth/teeth dental problems: Loose teeth	0.9	1.1	1.3	0.9	-1.1
Supplements: Vitamin C	0.9	1.0	2.0	0.2	1.4
Whole body fat-free mass	0.9	5.1	10.1	0.1	3.2
Long-standing illness, disability or infirmity	0.9	1.4	2.2	0.8	-1.5
Commuting to job workplace: Public transport	0.9	1.1	2.1	0.1	1.5
Ever smoked	0.9	1.5	2.5	0.7	1.6
Alzheimer’s Disease (in mother)	0.8	1.0	1.7	-0.5	1.3
Major Depression (MDD)	0.8	1.0	2.0	-1.4	0.0
Mean Putamen Volume	0.8	0.9	1.3	-0.7	1.1
Overall health rating	0.8	1.6	1.9	1.1	-1.4
Loneliness, isolation	0.8	1.1	1.7	1.3	0.8
Asthma (self-reported)	0.8	1.6	2.7	0.7	-1.6
Tinnitus: Yes, now most or all of the time	0.8	1.0	1.7	-1.3	0.5
Basal metabolic rate	0.8	4.6	9.2	0.2	3.0
Unable to work because of sickness or disability	0.8	1.0	2.0	1.4	0.2
Crohns Disease (2012)	0.7	1.1	2.2	-1.5	0.4
Waist Hip Ratio (WHR)	0.7	3.2	3.8	1.6	-1.9
Respiratory disease	0.7	1.6	3.0	-0.4	-1.7
Impedance of leg (right)	0.7	3.3	5.1	1.2	-2.2
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.4	-0.0	1.2
Allergy	0.7	1.5	1.7	-1.3	1.2
Alcohol intake versus 10 years previously	0.7	1.0	1.7	0.5	-1.3
Medication: Cholesterol lowering	0.7	1.0	1.1	1.0	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	0.8	-0.9	-0.9
Leg fat-free mass (right)	0.7	3.8	7.5	-0.2	2.7
Handedness (chirality/laterality): Left-handed	0.7	0.8	1.1	0.8	1.0
Ever had bowel cancer screening	0.7	0.8	1.2	-0.6	-1.1
Mineral and other dietary supplements	0.7	1.0	1.4	1.2	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	3.1	-0.0	1.8
Leg predicted mass (right)	0.7	3.8	7.6	-0.2	2.8
Pain type(s) experienced in last month: Hip pain	0.7	0.8	1.5	1.2	-0.4
Medication: Lisinopril	0.7	1.0	1.7	1.3	-0.5
Alcohol drinker status: Never	0.7	0.9	1.3	-1.1	-0.7
Diastolic blood pressure, automated reading	0.7	2.2	4.3	-0.2	-2.1
Ever depressed for a whole week	0.7	0.9	1.5	1.2	0.5
Commuting to job workplace: Cycle	0.7	0.9	1.6	-1.2	-0.5
Neuroticism (Nagel 2018)	0.6	1.3	2.6	-1.6	-0.1
HDL Cholesterol	0.6	1.0	1.5	-0.7	1.2
Allergy or Eczema	0.6	1.5	2.9	1.7	0.2
Hand grip strength (left)	0.6	1.5	2.9	0.4	1.7
Number of treatments/medications taken	0.6	1.1	1.8	1.4	0.7
Average weekly spirits intake	0.6	0.7	1.4	-1.2	0.2
Leg fat-free mass (left)	0.6	3.0	6.0	-0.3	2.4
Average weekly fortified wine intake	0.6	0.7	1.0	-1.0	0.6
Hayfever, allergic rhinitis or eczema	0.6	1.4	2.7	1.6	-0.1
Impedance of leg (left)	0.6	2.7	4.1	1.2	-2.0
Leg predicted mass (left)	0.6	3.0	6.0	-0.2	2.4
Medication: Ramipril	0.6	0.8	1.0	1.0	-0.8
Qualifications: A levels/AS levels or equivalent	0.6	1.4	2.2	-0.8	-1.5
Depression (self-reported)	0.6	0.7	1.3	-1.2	0.3
Pulse wave Arterial Stiffness index	0.6	0.7	1.3	-0.2	1.1
Number of full sisters	0.6	0.7	1.2	-0.4	-1.1
Suffer from ‘nerves’	0.6	1.0	1.6	0.6	-1.3
Mood swings	0.6	1.1	2.2	-1.5	0.3
Qualifications: nursing, teaching	0.6	1.0	1.6	-1.3	0.6
Medication: Aspirin	0.6	0.7	1.3	0.4	-1.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.0	-0.7	-1.0
High cholesterol (Self-reported)	0.6	1.0	1.1	1.1	1.0
Average weekly beer plus cider intake	0.6	0.8	1.3	1.1	0.6
Breast Cancer	0.5	1.3	2.5	0.3	1.6
Body Mass Index (BMI) (2010)	0.5	0.7	1.4	1.2	-0.1
Coronary Artery Disease (CAD)	0.5	0.6	1.1	0.3	1.0
Height	0.5	9.6	19.2	-0.2	4.4
Hypothyroidism (self reported)	0.5	1.2	2.5	0.1	-1.6
Stomach or abdominal pain in last month	0.5	0.6	1.2	1.1	-0.1
Medication: Levothyroxine sodium	0.5	0.9	1.8	0.0	-1.3
Alcohol usually taken with meals	0.5	0.8	1.0	-1.0	0.8
Medication: Simvastatin	0.5	0.8	1.5	1.2	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.5	-0.2	1.2
Falls in the last year	0.5	0.7	0.8	0.9	0.8
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	1.7	1.3	1.3
Medication: Lansoprazole	0.5	0.6	0.7	-0.7	0.8
Peak expiratory flow (PEF)	0.5	1.1	1.9	0.6	1.4
Blood clot in the leg (DVT)	0.5	0.7	0.9	0.9	-0.7
Medication: Allopurinol	0.5	0.7	0.8	0.7	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.0	-0.4	1.0
Illnesses of siblings: Diabetes	0.5	0.6	0.6	0.8	-0.7
Mother’s age at death	0.5	0.6	0.6	0.8	0.8
Medication: Atorvastatin	0.5	0.6	1.2	0.0	-1.1
Crohns Disease (2017)	0.4	0.9	1.2	-1.1	0.8
HbA1C	0.4	0.4	0.9	0.1	-0.9
Severe depression (siblings)	0.4	0.4	0.8	0.3	0.9
Hearing difficulty/problems with background noise	0.4	0.7	1.0	-1.0	0.6
Weight	0.4	2.0	4.1	0.1	2.0
Number of live births	0.4	0.6	1.1	-0.4	-1.0
Standing height	0.4	3.9	7.8	0.2	2.8
Breastfed as a baby	0.4	0.5	1.0	-1.0	-0.1
Gout (self-reported)	0.4	0.6	1.0	1.0	-0.3
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.6	0.2	-1.3
High blood pressure (siblings)	0.4	0.6	1.0	0.5	-1.0
Forced vital capacity (FVC), Best measure	0.4	1.5	2.8	0.5	1.7
Worry too long after embarrassment	0.4	0.7	1.2	-1.1	0.5
Age at first live birth	0.4	0.7	1.3	-1.2	0.3
Mean time to correctly identify matches	0.4	0.7	1.1	-1.0	0.6
Knee pain experienced in last month	0.4	0.7	1.4	1.2	-0.1
Diabetes diagnosed by doctor	0.4	0.6	0.9	0.6	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	0.9	0.9	-0.3
Age started oral contraceptive pill	0.4	0.5	0.6	-0.6	-0.7
Cholesterol lowering medication	0.4	0.6	0.7	0.7	0.8
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	0.6	0.7	-0.8
Bipolar Disorder or Schizophrenia	0.3	0.7	1.2	-1.1	0.3
Depressed Affect (Nagel 2018)	0.3	0.7	1.3	-1.1	-0.2
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.6	0.6	1.3
Worry (Nagel 2018)	0.3	0.7	0.8	-0.7	-0.9
Irritable Bowel Disease (IBD)	0.3	0.7	1.3	-1.2	-0.2
Ulcerative Colitis (UC)	0.3	0.6	0.9	-0.6	-0.9
Lupus	0.3	0.5	0.6	-0.6	0.8
Rheumatoid Arthritis	0.3	0.4	0.8	-0.9	-0.2
Cardiovascular Disease	0.3	0.9	1.8	-0.0	1.3
Neuroticism	0.3	0.7	1.2	-0.6	-1.1
Chronotype (morning person)	0.3	0.8	1.5	1.2	-0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.6	0.7	0.5
Diabetes (father)	0.3	0.3	0.5	0.7	-0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.6	0.3	0.8
Hair/balding pattern: Pattern 2	0.3	0.4	0.5	0.7	-0.5
Prospective memory result	0.3	0.4	0.7	0.2	-0.8
Illnesses of mother	0.3	0.3	0.6	0.8	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.5	0.5	0.7
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.0	-1.0	0.0
Number of full brothers	0.3	0.3	0.4	-0.7	-0.5
Wheeze or whistling in the chest in last year	0.3	0.6	1.1	1.0	-0.4
Pulse wave peak to peak time	0.3	0.3	0.5	0.3	-0.7
Qualifications: College or University degree	0.3	0.9	1.8	-1.3	0.2
Heart disease (mother)	0.3	0.4	0.7	0.3	-0.8
Leg pain on walking	0.3	0.4	0.8	0.9	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.7	-0.4	-0.8
Medication: Aspirin	0.3	0.4	0.5	0.5	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	1.3	1.1	-0.1
Eye problems/disorders: Cataract	0.3	0.4	0.7	-0.2	-0.8
Illnesses of father: None of the above (group 1)	0.3	0.4	0.7	-0.3	0.9
Pain experienced in last month	0.3	0.4	0.9	-0.9	-0.1
Depression (Nagel 2018)	0.2	0.3	0.7	-0.8	0.1
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.0	0.3	1.0
LDL Cholesterol	0.2	0.4	0.7	-0.3	-0.8
Neuroticism (2016)	0.2	0.2	0.4	-0.6	0.3
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.4	0.6	0.2
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.5	0.2	0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.5	0.2	-0.7
Hand grip strength (right)	0.2	0.6	0.9	0.5	1.0
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.2	0.5	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	0.8	-0.1	0.9
Medication: Atenolol	0.2	0.3	0.4	-0.6	-0.3
High blood pressure (mother)	0.2	0.3	0.6	-0.8	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	0.4	-0.3	0.6
Financial difficulties in last 2 years	0.2	0.3	0.4	-0.4	0.6
Fluid intelligence score	0.2	0.4	0.7	-0.2	0.9
Neuroticism score	0.2	0.4	0.6	-0.5	-0.8
Hip circumference	0.2	1.0	2.0	-0.3	1.4
Time employed in main current job	0.2	0.2	0.4	0.1	0.7
Worrier / anxious feelings	0.2	0.3	0.7	-0.8	0.0
Noisy workplace	0.2	0.2	0.5	0.7	0.2
Mouth/teeth dental problems: Dentures	0.2	0.3	0.5	-0.7	-0.2
Lung cancer (father)	0.2	0.3	0.5	0.7	-0.0
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.6	0.1	0.7
Age at last live birth	0.2	0.3	0.5	-0.4	0.7
Illnesses of father: Heart disease	0.2	0.3	0.6	-0.7	-0.3
Average weekly red wine intake	0.2	0.3	0.5	-0.3	0.7
Friendships satisfaction	0.2	0.2	0.2	0.5	-0.4
Medication for cholesterol	0.2	0.3	0.6	-0.8	0.3
Back pain experienced in last month	0.2	0.3	0.5	0.7	-0.2
Osteoarthritis (self-reported)	0.2	0.3	0.5	0.7	-0.0
Guilty feelings	0.2	0.3	0.3	-0.6	-0.6
Hearing aid user	0.2	0.2	0.4	-0.3	-0.6
Medication: Paracetamol	0.2	0.4	0.4	0.6	-0.6
Irritability	0.2	0.3	0.6	0.3	-0.7
Risk taking	0.2	0.2	0.3	0.5	-0.4
Basal cell carcinoma (self-reported)	0.2	0.2	0.3	-0.5	-0.3
Alcohol drinker status: Previous	0.2	0.3	0.5	-0.2	0.7
Schizophrenia (2018)	0.1	0.3	0.6	0.1	0.7
Ulcerative Colitis	0.1	0.2	0.3	-0.6	-0.2
Blood Eosinophil Count	0.1	1.0	1.3	0.8	-1.2
BMI	0.1	0.6	1.2	-1.1	0.3
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.2	0.2	-0.4
Tanning	0.1	1.1	2.1	-1.5	-0.2
Relative age of first facial hair	0.1	0.2	0.3	0.3	0.5
Diabetes (mother)	0.1	0.1	0.2	-0.1	-0.4
Trunk fat percentage	0.1	0.3	0.6	0.0	-0.8
Townsend deprivation index at recruitment	0.1	0.1	0.2	0.4	-0.1
Fed-up feelings	0.1	0.2	0.4	-0.0	-0.7
Taking other prescription medications	0.1	0.1	0.2	0.5	-0.0
Waist circumference	0.1	0.2	0.2	0.5	0.4
Had menopause	0.1	0.1	0.1	0.2	0.3
Had other major operations	0.1	0.2	0.2	-0.3	-0.5
Forced vital capacity (FVC)	0.1	0.4	0.4	0.6	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.5	0.7	-0.3
Mouth/teeth dental problems	0.1	0.1	0.3	-0.1	0.5
Diabetes (self-reported)	0.1	0.2	0.4	0.1	-0.6
Illnesses of siblings	0.1	0.2	0.2	-0.4	-0.4
Father’s age at death	0.1	0.1	0.1	-0.3	-0.3
Arm fat mass (right)	0.1	0.3	0.5	0.0	0.7
Hair/balding pattern: Pattern 4	0.1	0.1	0.1	0.4	0.4
Birth weight of first child	0.1	0.1	0.2	-0.2	-0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.2	-0.3	-0.4
Leg fat percentage (right)	0.1	0.2	0.5	0.7	-0.1
Number of children fathered	0.1	0.1	0.2	0.1	0.4
Eye problems/disorders: None of the above	0.1	0.1	0.2	-0.1	0.4
Medication: Blood pressure	0.1	0.1	0.2	0.4	-0.3
Migraine (self-reported)	0.1	0.2	0.3	0.0	-0.6
Leg fat mass (right)	0.1	0.3	0.3	0.6	0.6
Comparative height size at age 10	0.1	0.6	1.0	-0.4	1.0
Family relationship satisfaction	0.1	0.1	0.2	0.5	-0.2
Osteoporosis (self-reported)	0.1	0.2	0.3	-0.2	0.5
Arm fat mass (left)	0.1	0.2	0.4	0.1	0.7
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	0.5	-0.3
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.4	0.3
Medication: Blood pressure	0.1	0.2	0.3	0.4	-0.6
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.2	-0.5	-0.1
Medication: Bendroflumethiazide	0.1	0.2	0.4	-0.1	-0.6
Leg fat percentage (left)	0.1	0.2	0.4	0.6	0.1
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.3	-0.6	0.1
Leg fat mass (left)	0.1	0.4	0.6	0.5	0.8
Reaction Time	0.0	0.0	0.1	-0.2	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.0	0.0	0.1	0.3	-0.1
Schizophrenia (2014)	0.0	0.0	0.1	-0.1	0.3
Triglycerides	0.0	0.0	0.0	0.0	0.2
Blood Platelet Count	0.0	0.1	0.2	0.1	-0.5
Blood Red Count	0.0	0.2	0.3	0.6	-0.4
Blood White Count	0.0	0.0	0.1	0.3	-0.1
Heel T-Score	0.0	0.3	0.3	0.5	0.6
Smoking Status	0.0	0.1	0.1	0.2	-0.4
Lung FVC	0.0	0.2	0.2	0.4	0.5
Hair Pigment	0.0	1.0	1.7	1.3	0.5
Sensitivity / hurt feelings	0.0	0.0	0.0	-0.0	0.2
Relative age voice broke	0.0	0.0	0.0	0.1	-0.2
Age when periods started (menarche)	0.0	0.1	0.2	-0.4	0.2
High blood pressure	0.0	0.1	0.1	0.3	0.1
Body mass index (BMI)	0.0	0.2	0.4	-0.1	0.6
Trunk fat mass	0.0	0.1	0.1	0.1	0.3
Number of incorrect matches in round	0.0	0.1	0.1	-0.1	-0.3
Qualifications: None of the above	0.0	0.0	0.0	-0.1	-0.0
Heart attack	0.0	0.0	0.0	-0.0	-0.2
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.0	-0.1	-0.2
Arm fat percentage (right)	0.0	0.2	0.4	0.0	-0.6
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	-0.1	0.1
Body fat percentage	0.0	0.2	0.3	0.1	-0.6
Comparative body size at age 10	0.0	0.0	0.1	-0.3	0.1
Whole body fat mass	0.0	0.1	0.2	0.1	0.5
Hypertension (Self-reported)	0.0	0.0	0.0	0.1	-0.0
Arm fat percentage (left)	0.0	0.1	0.2	-0.3	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.0	0.1	0.1	0.2	0.2
Wears glasses or contact lenses	0.0	0.0	0.1	0.1	-0.3
Illnesses of father: High blood pressure	0.0	0.1	0.1	-0.3	0.1
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.1	-0.0	-0.3

Hub : Genes

CMTM5

Models

Trait associations