TWAS hub - C6orf170

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.099	0.029	2.7e-06	0.047	0.067	0.080	0.075	0.046	2.2e-06	1.3e-08	5.2e-10	2.1e-09	2.6e-06
2	TCGA	Ovarian Serous Cystadenocarcinoma	0.054	0.028	8.2e-04	0.015	0.036	0.023	NA	0.024	3.2e-02	1.7e-03	1.0e-02	NA	8.7e-03
3	TCGA	Thyroid Carcinoma	0.048	0.030	6.4e-03	0.048	0.009	0.018	NA	0.037	1.9e-05	3.6e-02	6.6e-03	NA	1.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse rate	8.2	13.9	27.2	0.6	-5.2	-3.7
Migraine (self-reported)	7.4	9.2	11.8	-2.8	-2.9	-3.4
Pulse rate, automated reading	5.8	18.8	37.1	0.7	-6.1	-4.4
Medication: Gliclazide	4.9	5.6	8.5	-0.8	-2.8	-2.9
Medication: Ramipril	4.8	6.1	12.4	3.5	0.3	2.4
Loud music exposure frequency	4.7	5.2	6.4	-2.1	-2.2	-2.5
Headache pain in last month	4.4	7.5	8.1	-2.6	-2.8	-2.9
Pulse wave reflection index	3.2	4.0	5.9	0.9	2.3	2.4
Age at last live birth	3.2	4.6	11.0	0.3	-3.3	-1.6
Tense / ‘highly strung’	3.1	5.2	8.3	-1.7	-2.9	-2.1
Family relationship satisfaction	2.8	3.4	8.6	2.9	-0.4	1.2
Basal cell carcinoma (self-reported)	2.6	3.1	6.7	1.5	0.7	2.6
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.2	6.1	-2.5	-1.3	-1.3
Hypertension (Self-reported)	2.5	7.0	13.4	3.7	1.0	2.6
Reason for reducing amount of alcohol drunk: Health precaution	2.4	2.8	5.1	-0.8	-1.6	-2.3
Mineral and other dietary supplements	2.4	3.2	7.7	2.8	-0.6	1.2
Fasting Glucose	2.3	2.8	4.6	-1.7	-1.0	-2.1
Medication: Ibuprofen	2.3	2.7	4.1	-2.0	-1.5	-1.4
Osteoporosis (self-reported)	2.3	2.8	3.6	-1.9	-1.5	-1.6
Commuting to job workplace: Cycle	2.3	2.7	6.4	-2.5	-0.4	-1.3
Time employed in main current job	2.2	2.5	4.4	0.4	2.1	1.7
Medication: Amlodipine	2.1	2.9	5.1	2.3	1.1	1.6
Number of self-reported non-cancer illnesses	2.1	3.6	7.0	2.6	-1.8	0.7
Average weekly champagne plus white wine intake	2.1	2.9	5.4	2.3	-0.5	1.7
Mean Putamen Volume	2.0	2.3	6.2	2.5	-0.9	-0.3
Vitamin and mineral supplements	2.0	2.8	5.3	2.3	1.0	1.4
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	4.2	0.4	2.0	1.6
Friendships satisfaction	2.0	2.4	5.1	2.3	-1.5	-0.2
Maternal smoking around birth	1.9	2.8	5.4	-0.2	-2.3	-1.7
Medication: Blood pressure	1.9	3.3	7.5	2.7	0.2	1.6
Number of full sisters	1.9	2.3	3.3	-1.0	-1.8	-1.7
Guilty feelings	1.9	2.9	4.2	-2.0	1.8	1.1
High blood pressure	1.8	5.1	10.4	3.2	0.8	2.0
Mouth/teeth dental problems: Mouth ulcers	1.8	2.8	4.1	-0.6	-2.0	-2.0
Multivitamins +/- minerals	1.7	2.1	6.1	-2.5	-0.4	-0.5
Supplements: Calcium	1.7	1.9	4.1	-2.0	0.4	-1.2
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	6.6	-2.6	0.5	-1.0
Ulcerative Colitis (UC)	1.5	2.8	7.6	2.8	-0.7	0.5
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	3.3	1.8	-1.1	0.8
Hair/balding pattern: Pattern 2	1.5	1.9	3.8	-1.9	1.3	0.3
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	4.0	1.7	-2.0	-0.7
Exposure to tobacco smoke at home	1.5	1.7	2.9	0.2	1.7	1.5
Age at first live birth	1.5	2.7	5.5	0.6	-2.4	-1.5
Neck or shoulder pain in last month	1.5	2.1	5.6	0.8	-2.4	-0.5
Alcohol intake frequency.	1.5	3.5	7.0	0.8	2.7	1.6
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	2.7	-1.3	-1.6	-1.1
HbA1C	1.4	1.5	2.7	1.6	0.1	1.4
Ulcerative Colitis	1.4	2.0	4.9	2.2	-0.9	0.5
Blood Red Count	1.4	13.2	26.3	0.3	5.1	3.6
BMI	1.4	8.4	15.6	4.0	0.7	3.0
Financial difficulties in last 2 years	1.4	1.9	5.6	2.4	0.2	0.5
Birth weight	1.4	3.0	4.1	-1.9	-1.2	-2.0
Commuting to job workplace: Public transport	1.4	1.6	3.4	1.0	-1.9	-0.7
Medication: Lisinopril	1.4	1.8	5.2	2.3	0.0	0.2
Illnesses of father: High blood pressure	1.4	1.7	3.1	1.8	-0.4	1.4
Vascular/heart problems diagnosed by doctor	1.4	3.7	8.4	-2.9	-0.4	-1.6
Qualifications: CSEs or equivalent	1.3	1.7	2.8	-0.6	-1.7	-1.4
Angina (self-reported)	1.3	1.7	2.3	0.8	1.5	1.5
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	3.2	1.8	-1.2	-0.5
Alcohol drinker status: Previous	1.3	1.5	4.2	-2.0	0.4	-0.3
Rheumatoid Arthritis	1.2	1.6	2.8	-0.7	-1.7	-1.3
Hearing difficulty/problems: Yes	1.2	1.9	3.8	-0.0	1.9	1.3
Hayfever, allergic rhinitis or eczema	1.2	2.6	4.5	-0.3	-2.1	-1.8
Waist circumference	1.2	4.3	6.8	2.1	1.1	2.6
Allergy	1.2	2.8	6.2	-0.3	2.5	1.5
Noisy workplace	1.2	1.5	3.6	-1.9	0.5	-0.7
Medication: Paracetamol	1.2	2.0	3.8	-0.7	-1.9	-1.2
Ever taken oral contraceptive pill	1.2	1.4	3.1	1.0	-1.8	-0.3
Irritable Bowel Disease (IBD)	1.1	2.6	6.9	2.6	-0.9	0.4
Reaction Time	1.1	2.2	4.2	1.1	-1.0	2.0
Medication: Atenolol	1.1	1.4	3.3	1.8	0.2	0.9
Back pain experienced in last month	1.1	1.6	3.8	2.0	0.2	1.0
High cholesterol (Self-reported)	1.1	1.9	4.2	-0.0	-2.0	-1.3
Alcohol drinker status: Never	1.1	1.3	2.2	1.5	0.7	1.2
Schizophrenia vs Biploar Disorder	1.0	1.4	2.1	0.6	1.4	1.3
Schizophrenia (2014)	1.0	2.3	3.3	0.6	1.8	1.8
Allergy or Eczema	1.0	2.7	4.5	-0.2	-2.1	-1.9
Cardiovascular Disease	1.0	3.3	7.3	2.7	-0.6	1.5
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	2.9	-0.5	1.7	0.5
Number of incorrect matches in round	1.0	1.7	3.2	-1.3	-0.4	-1.8
Chest pain or discomfort	1.0	1.5	2.9	1.7	-1.1	0.6
Miserableness	1.0	1.7	4.5	0.7	-2.1	-0.3
Supplements: Fish oil (including cod liver oil)	1.0	1.4	2.1	-1.4	-0.1	-1.5
Medication: Bendroflumethiazide	1.0	1.5	2.8	1.7	-1.3	-0.3
Unable to work because of sickness or disability	1.0	1.3	1.8	0.9	1.1	1.3
Number of treatments/medications taken	0.9	1.6	3.2	1.1	-1.8	-0.6
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.0	-1.4	-0.6	-1.0
Medication: Metformin	0.9	1.3	3.1	1.8	-0.9	0.1
Stomach or abdominal pain in last month	0.9	1.2	2.4	0.4	-1.5	-1.0
Impedance of arm (right)	0.9	4.0	7.8	-2.8	-0.8	-1.9
Lung cancer (father)	0.9	1.0	2.5	-0.6	1.6	0.5
Glaucoma (self-reported)	0.9	1.1	2.2	0.7	0.8	1.5
Mouth/teeth dental problems: Loose teeth	0.9	1.0	2.0	1.0	-1.4	0.0
Leg fat mass (right)	0.9	3.6	6.6	1.8	1.0	2.6
Breast cancer (self-reported)	0.9	1.1	2.6	1.6	-0.7	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	4.5	-2.1	0.9	-0.7
Wears glasses or contact lenses	0.9	1.0	1.6	-1.3	1.2	-0.2
Hearing aid user	0.9	1.0	1.6	-1.1	1.3	0.1
Leg fat mass (left)	0.9	3.5	6.5	1.7	1.0	2.5
Bipolar Disorder (2011)	0.8	0.8	1.0	-0.8	0.9	1.0
Diabetes (mother)	0.8	1.0	2.3	1.5	-0.9	-0.0
Alcohol usually taken with meals	0.8	1.3	2.9	1.7	0.3	0.9
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.4	0.7	0.3	1.6
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.9	-1.7	-0.1	-0.1
Leg fat percentage (right)	0.8	2.9	4.7	1.9	0.7	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	2.8	-0.3	1.7	0.0
Commuting to job workplace: Walk	0.8	0.8	1.9	1.4	0.3	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.2	-1.5	-0.3	-0.8
Leg fat percentage (left)	0.8	2.7	4.5	1.7	0.8	2.1
Diastolic blood pressure, automated reading	0.8	2.6	5.9	1.3	-2.4	-0.2
Ovarian Cancer	0.7	0.9	1.7	-1.3	-0.0	-1.0
Body Mass Index (BMI) (2010)	0.7	1.0	2.6	1.6	-0.3	0.7
Neuroticism (2016)	0.7	1.0	1.7	1.2	0.3	1.3
Diabetes (father)	0.7	0.9	1.4	1.2	-1.0	-0.3
Relative age voice broke	0.7	1.0	1.6	-1.3	-1.2	-0.5
High blood pressure (mother)	0.7	1.0	2.2	1.5	0.0	0.8
Impedance of arm (left)	0.7	3.4	6.8	-2.6	-0.4	-1.8
Length of working week for main job	0.7	0.8	1.1	-0.9	1.0	0.7
Arm fat-free mass (right)	0.7	3.4	5.1	1.6	1.5	2.2
Medication for pain relief, constipation, heartburn	0.7	1.2	2.9	-0.2	1.7	0.8
Overall health rating	0.7	1.6	2.4	1.4	-1.6	0.6
Mother’s age at death	0.7	0.8	1.9	-0.6	1.4	0.5
Age started oral contraceptive pill	0.7	0.9	1.4	-1.2	-0.9	-0.6
Verbal and Numeric Reasoning (VNR)	0.6	1.5	4.1	2.0	-0.4	0.6
Type 2 Diabetes (T2D) (2018)	0.6	1.2	1.7	1.3	0.8	1.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.5	0.7	-1.2	-0.5
Medication for hormone replacement therapy	0.6	0.6	1.8	1.4	-0.1	0.1
Supplements: Zinc	0.6	0.6	1.2	-1.1	0.8	-0.2
Taking other prescription medications	0.6	1.0	1.5	1.2	-1.2	-0.0
Body mass index (BMI)	0.6	2.7	4.2	2.0	0.2	2.0
Had menopause	0.6	0.8	1.4	-0.6	1.2	0.8
Qualifications: None of the above	0.6	1.4	3.4	-1.8	0.2	-0.8
Hair/balding pattern: Pattern 3	0.6	0.8	1.5	1.2	-0.5	-0.9
Qualifications: A levels/AS levels or equivalent	0.6	1.4	1.6	-1.2	-1.3	-1.1
Breastfed as a baby	0.6	0.8	1.2	-0.9	1.1	0.5
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.3	0.7	-1.1	0.6
Wheeze or whistling in the chest in last year	0.6	1.0	2.3	-0.8	-1.5	-0.4
Emphysema/chronic bronchitis	0.6	0.7	0.9	0.5	1.0	0.9
Mean time to correctly identify matches	0.6	1.1	2.4	0.7	-0.7	1.6
Arm predicted mass (right)	0.6	3.1	4.8	1.6	1.4	2.2
Leg pain on walking	0.6	0.7	1.3	-1.1	0.9	0.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.3	0.2	1.1	0.9
Asthma (self-reported)	0.6	1.2	2.0	1.4	-1.3	0.3
Medication: Blood pressure	0.6	1.2	2.5	1.6	0.7	0.7
Medication: Paracetamol	0.6	0.9	2.3	-0.1	-1.5	-0.6
Medication: Atorvastatin	0.6	0.7	1.7	0.5	-1.3	-0.4
Intelligence (Savage-Jansen 2018)	0.5	1.4	3.4	1.9	-0.8	0.3
Worry (Nagel 2018)	0.5	1.1	1.5	-1.2	-1.2	-0.7
Alzheimer’s Disease (in father)	0.5	0.6	0.9	0.8	-1.0	0.4
Crohns Disease (2012)	0.5	0.9	1.6	0.1	-1.3	-1.0
Ever had hysterectomy (womb removed)	0.5	0.5	1.1	-0.1	1.1	0.7
Average weekly fortified wine intake	0.5	0.6	1.8	1.3	-0.1	0.0
Age when periods started (menarche)	0.5	1.2	2.4	-0.4	-1.0	-1.6
Serious illness, injury or assault to yourself	0.5	0.6	1.3	-0.8	-1.1	-0.2
Chronic bronchitis/emphysema (father)	0.5	0.6	1.3	-0.5	1.1	0.4
Fluid intelligence score	0.5	1.1	2.2	1.5	0.0	1.1
Falls in the last year	0.5	0.7	1.1	-1.0	-0.7	-0.8
Happiness	0.5	0.6	0.9	0.9	0.0	1.0
Medication: Cholesterol lowering	0.5	0.7	1.2	1.1	-0.9	0.5
Birth weight of first child	0.5	0.9	2.4	-1.5	0.6	0.1
Gout (self-reported)	0.5	0.7	1.0	-0.5	1.0	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.5	1.2	0.1	0.8
Medication: Omeprazole	0.5	0.6	0.8	0.8	-0.9	-0.7
Whole body fat mass	0.5	2.1	3.8	1.5	0.5	2.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.2	0.8	-0.3	1.1
Medication: Aspirin	0.5	0.7	1.2	1.0	0.2	1.1
Supplements: Vitamin C	0.5	0.6	1.6	-1.2	0.4	-0.3
Illnesses of father: Heart disease	0.5	0.7	1.4	-1.2	-0.0	-0.8
Diabetes diagnosed by doctor	0.5	0.8	2.1	1.4	-0.1	0.4
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.5	1.2	-0.6	0.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.5	0.3	0.5	1.2
Ever depressed for a whole week	0.5	0.6	1.0	-0.4	-1.0	-0.8
Cholesterol lowering medication	0.5	0.8	1.2	-1.1	0.3	-1.1
Depressed Affect (Nagel 2018)	0.4	0.8	1.7	1.3	-0.9	0.2
Depression (Nagel 2018)	0.4	0.6	1.2	-0.0	0.7	1.1
Schizophrenia (2018)	0.4	0.9	1.5	0.3	1.2	1.1
Alzheimer’s Disease (including proxy)	0.4	0.5	1.2	0.6	-1.1	0.2
Breast Cancer	0.4	0.9	2.2	-0.6	1.5	0.2
Coronary Artery Disease (CAD)	0.4	0.4	1.2	-0.1	1.1	0.3
Systolic Blood Pressure	0.4	2.0	3.7	-0.1	1.5	1.9
Relative age of first facial hair	0.4	0.8	1.9	-1.4	0.5	-0.5
Systolic blood pressure, automated reading	0.4	1.0	1.7	-0.3	1.2	1.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	0.8	0.6	-0.4	-0.9
Angina	0.4	0.6	0.9	0.5	0.9	0.7
Leg fat-free mass (left)	0.4	2.0	4.0	1.2	0.8	2.0
Leg predicted mass (left)	0.4	2.1	4.0	1.3	0.8	2.0
Trunk fat mass	0.4	1.8	3.8	1.1	0.7	1.9
Forced vital capacity (FVC)	0.4	1.5	1.8	-1.3	-1.0	-1.3
Mouth/teeth dental problems	0.4	0.6	1.6	-1.3	0.4	0.0
Neuroticism score	0.4	0.9	1.9	-0.8	-1.4	-0.5
Weight	0.4	2.1	3.9	1.4	0.7	2.0
Father’s age at death	0.4	0.5	0.7	0.8	-0.1	0.9
Asthma	0.4	0.7	1.3	1.2	-0.8	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	2.1	-1.5	-0.6	-0.9
Pulse wave Arterial Stiffness index	0.4	0.4	0.9	0.9	-0.0	0.6
Arm fat mass (right)	0.4	1.6	2.8	1.4	0.1	1.7
High blood pressure (siblings)	0.4	0.6	1.6	1.3	-0.2	-0.3
Body fat percentage	0.4	1.4	2.9	1.1	0.5	1.7
Comparative body size at age 10	0.4	1.0	2.4	1.6	-0.8	0.3
Medication: Allopurinol	0.4	0.5	1.2	-1.1	0.7	0.2
Medication: Seretide 50 evohaler	0.4	0.5	1.4	-1.2	-0.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	0.9	-0.2	-0.9	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.7	0.2	0.9	0.7
Medication: Aspirin	0.4	0.5	0.9	0.9	0.1	0.7
Arm fat mass (left)	0.4	1.8	3.2	1.4	0.2	1.8
Ever smoked	0.4	0.7	2.1	0.1	-1.4	-0.3
Basal metabolic rate	0.4	2.0	3.3	1.4	0.8	1.8
Arm fat-free mass (left)	0.4	1.8	2.4	1.5	0.9	1.6
Myopia	0.4	0.6	1.2	-1.1	0.3	-0.7
Heart disease (siblings)	0.4	0.5	1.1	-0.2	-1.0	-0.6
Impedance of whole body	0.4	2.1	4.2	-2.0	0.3	-1.4
Arm predicted mass (left)	0.4	2.2	3.0	1.6	0.9	1.7
Bipolar Disorder or Schizophrenia	0.3	0.8	1.5	0.1	1.2	0.9
Primary Biliary Cirrhosis	0.3	0.5	1.1	0.4	-1.1	0.3
Triglycerides	0.3	0.5	1.1	0.6	0.4	1.1
Blood White Count	0.3	1.9	2.5	1.6	1.1	1.4
Waist Hip Ratio (WHR)	0.3	1.1	1.8	0.1	1.3	1.3
Hypothyroidism (self reported)	0.3	0.6	1.8	1.3	0.2	0.2
Respiratory disease	0.3	0.7	1.3	1.1	-0.5	0.7
Neuroticism	0.3	0.8	2.1	-0.2	-1.4	0.5
Sensitivity / hurt feelings	0.3	0.4	0.6	-0.8	-0.7	-0.3
Medication: Co-codamol	0.3	0.4	1.0	1.0	-0.3	0.3
Trunk fat percentage	0.3	1.2	2.6	0.8	0.5	1.6
Townsend deprivation index at recruitment	0.3	0.5	1.2	-1.1	0.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.3	0.2	0.9	1.1
Supplements: Glucosamine	0.3	0.4	0.8	-0.9	0.4	0.4
Medication: Levothyroxine sodium	0.3	0.5	1.2	1.1	0.5	-0.2
Past tobacco smoking	0.3	0.5	1.5	-0.2	1.2	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.0	0.4	-1.0	0.1
Had other major operations	0.3	0.4	0.8	-0.9	0.1	0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.6	0.8	-0.8	-0.2
Hip circumference	0.3	1.4	2.2	1.3	-0.4	1.5
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	1.0	-1.0	-0.8	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.7	0.5	0.8	0.8
Hair/balding pattern: Pattern 4	0.3	0.7	1.1	-0.8	1.1	0.6
Peak expiratory flow (PEF)	0.3	0.7	1.6	-1.3	-0.5	-0.6
Forced vital capacity (FVC), Best measure	0.3	1.2	1.7	-1.3	-0.8	-1.1
Number of full brothers	0.3	0.4	1.2	-0.1	-0.2	-1.1
Pulse wave peak to peak time	0.3	0.3	0.6	-0.8	-0.1	-0.6
Shortness of breath walking on level ground	0.3	0.3	0.9	1.0	-0.0	0.1
Eye problems/disorders: None of the above	0.3	0.4	1.0	0.1	1.0	0.2
Heart disease (mother)	0.3	0.3	0.9	0.9	-0.3	0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.7	-0.8	0.7	0.0
Smoking status: Previous	0.3	0.4	0.7	0.9	-0.6	0.3
Whole body fat-free mass	0.3	1.7	2.7	1.3	0.7	1.6
Leg fat-free mass (right)	0.3	1.5	2.9	1.0	0.7	1.7
Arm fat percentage (left)	0.3	1.1	1.9	1.2	-0.4	1.4
Long-standing illness, disability or infirmity	0.3	0.4	0.8	0.9	-0.1	0.7
Medication for cholesterol	0.3	0.5	1.4	-1.2	-0.1	0.3
Whole body water mass	0.3	1.5	2.4	1.3	0.7	1.6
Leg predicted mass (right)	0.3	1.3	2.7	1.0	0.6	1.7
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.9	-0.4	0.3	-0.9
Eye problems/disorders: Glaucoma	0.3	0.4	0.5	0.5	-0.7	0.6
Average weekly beer plus cider intake	0.3	0.4	0.7	-0.8	0.2	0.7
Irritability	0.3	0.5	1.4	0.1	-1.2	0.5
Risk taking	0.3	0.4	0.6	0.0	0.7	0.8
Heart attack/myocardial infarction (self-reported)	0.3	0.3	0.5	0.7	0.4	0.5
Crohns Disease (2017)	0.2	0.5	1.4	1.2	-0.3	0.1
Major Depression (MDD)	0.2	0.2	0.6	0.8	-0.1	0.0
Heel T-Score	0.2	1.2	3.3	-1.8	0.5	0.4
Smoking Status	0.2	0.5	1.1	0.5	-1.1	0.3
Lung FEV1/FVC ratio	0.2	0.8	1.6	-0.1	1.3	0.9
Hand grip strength (left)	0.2	0.4	1.0	-0.4	1.0	0.3
Fed-up feelings	0.2	0.3	0.9	0.3	-0.9	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.5	0.6	-0.3	0.7
Impedance of leg (left)	0.2	0.9	1.5	-1.2	0.3	-1.1
Nervous feelings	0.2	0.4	0.6	-0.8	-0.1	0.8
Heart attack	0.2	0.3	0.4	0.6	0.4	0.6
Diabetes (self-reported)	0.2	0.3	0.8	0.9	0.1	-0.0
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.8	-0.9	-0.3	0.2
Medication: Simvastatin	0.2	0.3	0.9	1.0	0.2	0.3
Arm fat percentage (right)	0.2	1.0	1.4	1.1	-0.5	1.2
Trunk fat-free mass	0.2	1.4	2.0	1.4	0.5	1.4
Alcohol intake versus 10 years previously	0.2	0.3	0.4	-0.2	0.7	0.6
Number of live births	0.2	0.2	0.3	-0.3	0.5	0.6
Mouth/teeth dental problems: Dentures	0.2	0.4	0.7	0.6	-0.3	-0.8
Depression (self-reported)	0.2	0.2	0.5	-0.7	0.4	0.2
Medication: Lansoprazole	0.2	0.2	0.4	0.5	0.6	0.0
Prospective memory result	0.2	0.2	0.5	0.2	0.7	0.1
Trunk predicted mass	0.2	1.4	1.9	1.4	0.6	1.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.5	0.7	0.3	0.5
Blood clot in the leg (DVT)	0.2	0.2	0.5	-0.3	-0.7	0.3
Exposure to tobacco smoke outside home	0.2	0.3	0.6	0.8	0.1	0.5
Worry too long after embarrassment	0.2	0.3	0.5	-0.7	-0.7	-0.2
Number of children fathered	0.2	0.2	0.6	0.4	0.8	-0.1
Qualifications: College or University degree	0.2	0.6	1.2	1.1	-0.5	0.8
Had major operations	0.2	0.3	0.7	-0.1	0.3	0.8
Average weekly red wine intake	0.2	0.3	0.6	-0.4	-0.4	-0.8
Mood swings	0.2	0.4	1.1	-0.2	-1.0	-0.5
Osteoarthritis (self-reported)	0.2	0.2	0.4	-0.6	0.6	0.1
Smoking status: Current	0.2	0.3	0.6	-0.8	-0.2	0.3
Financial situation satisfaction	0.2	0.3	0.4	0.1	-0.6	-0.6
Fractured/broken bones in last 5 years	0.2	0.2	0.3	0.5	-0.6	-0.0
Pain experienced in last month	0.2	0.4	0.6	-0.6	0.3	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.8	-0.2	-0.1	0.9
Pack years of smoking	0.2	0.3	0.9	1.0	0.2	-0.2
Bipolar Disorder (2018)	0.1	0.1	0.3	-0.3	0.5	0.2
Neuroticism (Nagel 2018)	0.1	0.2	0.5	-0.3	-0.7	0.2
Age at First Birth	0.1	0.2	0.6	-0.7	0.2	-0.1
Lupus	0.1	0.2	0.3	-0.5	0.2	-0.6
Blood Platelet Count	0.1	1.0	1.4	1.2	-1.1	0.8
Height	0.1	2.7	4.8	-2.2	1.8	-0.5
Lung FVC	0.1	0.3	0.5	-0.5	0.0	-0.7
Tanning	0.1	1.7	3.1	1.2	0.7	1.8
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.5	-0.7	0.4	-0.0
Severe depression (siblings)	0.1	0.2	0.3	-0.5	-0.0	0.5
Pack years adult smoking proportion	0.1	0.2	0.5	0.7	-0.2	-0.3
Impedance of leg (right)	0.1	0.5	0.8	-0.8	0.2	-0.9
Hand grip strength (right)	0.1	0.2	0.5	0.7	0.3	-0.1
Current tobacco smoking	0.1	0.2	0.6	-0.8	-0.3	-0.0
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.6	-0.0	-0.3
Sitting height	0.1	0.5	0.7	0.8	0.9	0.5
Hearing difficulty/problems with background noise	0.1	0.1	0.2	0.3	0.5	0.3
Pain all over the body in last month	0.1	0.1	0.2	0.2	-0.1	0.4
Illnesses of siblings	0.1	0.2	0.3	-0.4	0.1	0.5
Worrier / anxious feelings	0.1	0.2	0.6	-0.1	-0.4	-0.8
Illnesses of mother	0.1	0.1	0.3	-0.6	0.1	-0.2
Standing height	0.1	0.7	1.3	-1.1	1.0	-0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.1	0.4	0.1	0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.5	0.7	0.4	-0.4
Health satisfaction	0.1	0.2	0.5	0.0	-0.2	0.7
Suffer from ‘nerves’	0.1	0.1	0.2	-0.4	-0.5	0.2
Knee pain experienced in last month	0.1	0.2	0.4	0.5	-0.1	0.6
Illnesses of siblings: Diabetes	0.1	0.1	0.2	0.4	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.3	0.0	0.6	0.5
Ever had bowel cancer screening	0.1	0.1	0.2	-0.5	-0.1	0.1
Qualifications: nursing, teaching	0.1	0.1	0.4	-0.6	0.0	-0.2
Eye problems/disorders: Cataract	0.1	0.1	0.1	0.3	-0.4	0.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.1	-0.3	0.3	-0.3
Number of operations (self-reported)	0.1	0.2	0.5	-0.3	-0.1	0.7
Alzheimer’s Disease (in mother)	0.0	0.0	0.1	-0.3	-0.1	0.2
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.1	0.1	-0.3	0.2	-0.2
LDL Cholesterol	0.0	0.0	0.1	-0.2	0.3	-0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	0.3	-0.2	-0.0
Blood Eosinophil Count	0.0	0.3	0.6	-0.5	-0.7	-0.3
Chronotype (morning person)	0.0	0.1	0.3	-0.1	0.1	0.5
Hair Pigment	0.0	0.1	0.1	0.4	0.4	0.3
Average weekly spirits intake	0.0	0.0	0.1	0.1	0.2	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.2	-0.1	0.3	0.4
Comparative height size at age 10	0.0	0.0	0.1	-0.2	0.2	-0.0
Loneliness, isolation	0.0	0.1	0.1	0.3	-0.3	-0.1

Hub : Genes

C6orf170

Models

Trait associations