TWAS hub - NGDN

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Skin Sun Exposed Lower leg	0.085	0.034	0.0070	0.021	NA	0.005	NA	0.006	0.00720	NA	0.1200	NA	0.092
2	TCGA	Thyroid Carcinoma	0.046	0.023	0.0048	0.030	0.012	0.018	NA	0.011	0.00064	0.021	0.0059	NA	0.025

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pulse rate, automated reading	22.3	72.2	95.5	-7.0	9.8
Pulse rate	16.8	28.3	34.2	-4.7	5.8
Number of full sisters	6.2	7.6	10.2	-3.2	2.2
Pulse wave reflection index	5.7	7.1	8.9	2.3	-3.0
Alcohol drinker status: Never	5.2	6.3	8.8	-3.0	1.9
Qualifications: CSEs or equivalent	4.2	5.5	10.8	-0.5	3.3
Ever unenthusiastic/disinterested for a whole week	4.1	5.1	8.3	2.9	1.4
Ever had prostate specific antigen (PSA) test	4.1	4.8	6.5	2.6	-1.7
Commuting to job workplace: Public transport	4.0	4.8	6.9	2.6	1.6
Risk taking	3.4	4.9	5.8	-2.4	2.0
Financial situation satisfaction	3.3	4.1	5.6	-1.6	2.4
Medication: Omeprazole (e.g. Zanprol)	3.3	4.0	7.1	2.7	-0.9
Current tobacco smoking	3.2	5.3	9.8	-0.8	3.1
Medication: Ventolin 100micrograms inhaler	3.2	4.2	7.9	-2.8	0.7
Relative age of first facial hair	3.0	6.2	8.6	2.9	-1.9
Schizophrenia vs Biploar Disorder	2.8	3.8	7.0	-0.7	-2.6
Smoking status: Current	2.8	4.4	8.1	-0.8	2.8
Medication: Atorvastatin	2.8	3.5	6.6	-0.6	2.6
Angina (self-reported)	2.5	3.3	6.5	-0.3	2.6
Illnesses of father: Heart disease	2.5	3.5	5.4	-1.2	2.3
Medication: Omeprazole	2.4	2.9	5.7	2.4	-0.4
Angina	2.3	3.0	5.9	-0.4	2.4
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.5	3.3	-1.3	-1.8
Migraine (self-reported)	2.2	2.8	5.4	-2.3	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.2	2.6	2.7	1.6	-1.6
Primary Biliary Cirrhosis	2.1	3.0	3.7	-1.9	1.5
Tense / ‘highly strung’	2.1	3.5	6.6	-2.6	0.7
Peak expiratory flow (PEF)	2.1	4.9	9.7	3.1	-0.2
Diastolic blood pressure, automated reading	2.1	6.6	9.8	-1.8	3.1
Bipolar Disorder (2018)	2.0	3.2	3.9	-2.0	1.6
Happiness	2.0	2.4	4.0	0.8	2.0
Alzheimer’s Disease (in father)	1.9	2.0	3.7	0.6	-1.9
Fasting Glucose	1.9	2.3	2.5	1.4	1.6
Relative age voice broke	1.9	2.9	3.0	1.7	-1.7
Forced expiratory volume in 1-second (FEV1)	1.9	6.5	12.9	3.6	-0.1
Exposure to tobacco smoke at home	1.9	2.1	3.9	-0.6	2.0
Back pain experienced in last month	1.9	2.7	4.5	0.9	2.1
Shortness of breath walking on level ground	1.8	2.1	2.3	-1.4	1.5
Osteoporosis (self-reported)	1.8	2.3	4.0	0.8	-2.0
Maternal smoking around birth	1.7	2.5	3.6	-1.1	1.9
Serious illness, injury or assault to yourself	1.7	2.1	4.1	2.0	-0.3
Serious illness, injury or assault of a close relative in last 2 years	1.7	2.0	3.4	1.9	-0.7
Eye problems/disorders: Glaucoma	1.7	2.0	3.9	2.0	-0.2
Verbal and Numeric Reasoning (VNR)	1.5	3.6	5.6	1.3	-2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.2	6.3	2.5	0.3
Heart attack/myocardial infarction (self-reported)	1.5	1.9	3.2	0.8	1.8
Lupus	1.4	2.2	3.7	0.8	1.9
Ever had hysterectomy (womb removed)	1.4	1.6	3.2	-1.8	0.1
Length of working week for main job	1.4	1.5	2.9	-0.3	1.7
Alcohol intake frequency.	1.4	3.4	6.3	-0.7	2.5
Smoking status: Previous	1.4	2.1	3.6	0.7	-1.9
Medication: Blood pressure	1.4	2.6	4.6	-0.8	2.2
Intelligence (Savage-Jansen 2018)	1.3	3.9	5.5	1.5	-2.3
Hand grip strength (left)	1.3	3.5	3.9	2.0	-1.7
Average weekly fortified wine intake	1.3	1.5	3.0	-0.1	-1.7
Forced vital capacity (FVC)	1.3	4.9	9.6	3.1	-0.4
Heart attack	1.3	1.7	2.8	0.8	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.2	8.1	2.8	-0.6
Worry too long after embarrassment	1.3	2.2	3.1	1.7	-1.1
Emphysema/chronic bronchitis	1.3	1.4	2.7	-0.4	1.6
Chest pain or discomfort	1.3	1.9	2.3	-1.5	1.2
Age at last live birth	1.3	1.9	2.9	1.7	-1.0
Medication: Aspirin	1.3	1.7	2.1	1.2	1.4
Schizophrenia (2018)	1.2	2.4	4.0	-1.0	-2.0
Mean Putamen Volume	1.2	1.4	2.5	-1.6	-0.5
Alcohol usually taken with meals	1.2	1.9	2.7	1.6	-1.0
Eye problems/disorders: Cataract	1.2	1.4	2.1	-1.5	0.8
Medication: Aspirin	1.2	1.6	2.7	0.7	1.6
LDL Cholesterol	1.1	1.7	3.2	-1.8	-0.3
Height	1.1	21.1	24.6	4.2	-5.0
Medication for hormone replacement therapy	1.1	1.3	1.6	1.0	-1.2
Alzheimer’s Disease (including proxy)	1.0	1.4	2.8	0.3	-1.7
Breast Cancer	1.0	2.3	3.7	1.0	-1.9
Schizophrenia (2014)	1.0	2.3	2.6	-1.4	-1.6
Fed-up feelings	1.0	1.8	2.5	1.0	-1.6
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.2	-0.4	1.5
Medication for pain relief, constipation, heartburn	1.0	1.7	2.7	-0.8	-1.6
Miserableness	1.0	1.7	2.6	-1.0	-1.6
Alcohol drinker status: Previous	1.0	1.2	2.3	1.5	-0.3
Bipolar Disorder or Schizophrenia	0.9	2.1	4.0	-2.0	-0.6
Pain all over the body in last month	0.9	1.0	1.8	0.4	-1.3
Fluid intelligence score	0.9	1.9	3.1	0.8	-1.8
Time employed in main current job	0.9	1.0	1.9	-1.4	0.4
Alcohol intake versus 10 years previously	0.9	1.3	2.6	1.6	0.1
Forced vital capacity (FVC), Best measure	0.9	3.2	5.7	2.4	-0.8
Medication: Seretide 50 evohaler	0.9	1.0	1.1	1.1	0.9
Suffer from ‘nerves’	0.9	1.3	2.6	-0.3	1.6
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.0	2.0	-1.4	0.3
Commuting to job workplace: Car/motor vehicle	0.9	1.1	2.1	-1.4	0.3
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.2	-1.5	-0.1
Ever taken oral contraceptive pill	0.9	1.0	1.1	-0.9	1.1
Ovarian Cancer	0.8	1.0	2.0	1.4	0.0
Rheumatoid Arthritis	0.8	1.1	1.9	-0.6	1.4
Hypothyroidism (self reported)	0.8	1.8	3.2	-0.6	1.8
Lung FEV1/FVC ratio	0.8	4.1	8.1	2.8	0.4
Supplements: Zinc	0.8	0.9	1.3	-1.2	0.6
Had menopause	0.8	1.0	1.3	-1.1	-0.9
Hair/balding pattern: Pattern 3	0.8	1.2	2.3	0.3	-1.5
Medication: Cholesterol lowering	0.8	1.3	2.1	1.5	0.6
Comparative body size at age 10	0.8	2.1	4.1	2.0	0.3
Age at first live birth	0.8	1.4	2.4	1.5	-0.6
Health satisfaction	0.8	1.1	1.2	1.0	1.1
Neck or shoulder pain in last month	0.8	1.1	1.8	-1.3	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	1.1	0.8	-1.1
Average weekly red wine intake	0.8	1.2	1.3	1.0	-1.1
Arm fat-free mass (left)	0.8	3.9	7.7	2.8	-0.2
Cholesterol lowering medication	0.8	1.1	1.6	-0.8	1.2
Supplements: Calcium	0.8	0.9	1.8	0.1	-1.4
Heart disease (siblings)	0.8	1.0	1.8	0.4	-1.4
Major Depression (MDD)	0.7	0.8	1.5	-1.2	0.4
Waist Hip Ratio (WHR)	0.7	3.0	5.6	0.7	2.4
Respiratory disease	0.7	1.6	2.1	-1.0	1.5
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.6	1.3	-0.3
Medication: Metformin	0.7	0.9	1.6	-1.3	-0.5
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.3	0.5	1.1
Stomach or abdominal pain in last month	0.7	0.8	0.9	0.9	0.9
Sitting height	0.7	4.9	7.0	2.6	-1.7
Past tobacco smoking	0.7	1.2	2.0	-0.6	1.4
Falls in the last year	0.7	1.0	1.6	1.3	-0.6
Standing height	0.7	6.9	9.8	3.1	-2.0
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.5	0.4	1.2
Medication: Amlodipine	0.7	1.0	1.0	-1.0	0.9
Exposure to tobacco smoke outside home	0.7	1.0	1.4	0.7	1.2
Number of children fathered	0.7	0.8	1.5	-0.0	-1.2
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.3	-0.5	1.2
Medication: Ibuprofen	0.7	0.8	1.7	-0.2	-1.3
Overall health rating	0.7	1.4	1.9	1.0	1.4
Loneliness, isolation	0.7	1.0	1.8	1.4	-0.5
Number of operations (self-reported)	0.7	1.0	1.5	-1.2	0.8
Arm predicted mass (left)	0.7	3.8	7.4	2.7	-0.3
Prostate Cancer	0.6	0.8	1.6	-0.3	1.2
HbA1C	0.6	0.6	1.2	-0.3	-1.1
Type 2 Diabetes (T2D) (2012)	0.6	0.7	0.8	0.8	0.9
Hearing difficulty/problems: Yes	0.6	0.8	0.9	-1.0	-0.9
Hand grip strength (right)	0.6	1.6	2.2	1.5	-1.0
Age when periods started (menarche)	0.6	1.5	1.5	1.2	-1.2
Multivitamins +/- minerals	0.6	0.7	1.3	1.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	1.5	-1.2	-0.7
Hearing difficulty/problems with background noise	0.6	1.0	1.3	-1.1	-0.8
Medication: Ramipril	0.6	0.8	1.5	-0.0	1.2
Mouth/teeth dental problems: Dentures	0.6	1.1	1.5	-1.2	-0.8
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	1.9	-1.4	0.3
Birth weight	0.6	1.2	1.8	1.3	-0.8
Eye problems/disorders: None of the above	0.6	0.7	1.2	-0.4	-1.1
Wears glasses or contact lenses	0.6	0.7	0.9	-1.0	-0.6
Tinnitus: Yes, now most or all of the time	0.6	0.7	0.8	-0.8	-0.9
Illnesses of father: High blood pressure	0.6	0.7	1.4	0.3	1.2
Pack years of smoking	0.6	0.9	1.3	1.2	-0.6
Alzheimer’s Disease (in mother)	0.5	0.6	1.1	-0.1	-1.0
Reaction Time	0.5	1.0	2.0	-1.4	0.2
Age at First Birth	0.5	0.7	0.8	0.8	-0.9
Crohns Disease (2012)	0.5	0.8	1.5	-1.2	-0.1
Lung FVC	0.5	2.4	4.7	2.2	-0.1
Sensitivity / hurt feelings	0.5	0.8	1.1	0.7	-1.1
Pack years adult smoking proportion	0.5	0.8	1.5	1.2	-0.5
Taking other prescription medications	0.5	0.8	1.1	1.1	-0.6
Had other major operations	0.5	0.6	1.1	0.0	-1.1
Mouth/teeth dental problems	0.5	0.8	1.1	1.0	-0.7
Trunk fat-free mass	0.5	2.7	5.3	2.3	-0.3
Father’s age at death	0.5	0.7	0.9	-1.0	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.5	1.2	-0.2
Trunk predicted mass	0.5	2.6	5.1	2.3	-0.3
Breastfed as a baby	0.5	0.6	1.1	-0.4	1.1
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.0	-0.6	1.0
Medication: Paracetamol	0.5	0.8	1.5	-0.4	1.2
Arm fat-free mass (right)	0.5	2.5	5.0	2.2	-0.0
Arm predicted mass (right)	0.5	2.6	5.2	2.3	-0.3
Knee pain experienced in last month	0.5	0.8	1.0	-1.0	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.3	1.1	-0.6
Illnesses of father: None of the above (group 1)	0.5	0.7	1.3	0.0	-1.1
Ever smoked	0.5	0.9	1.4	0.6	-1.2
Fractured/broken bones in last 5 years	0.5	0.6	1.0	1.0	-0.5
Vascular/heart problems diagnosed by doctor	0.5	1.4	2.7	-0.2	-1.6
Irritable Bowel Disease (IBD)	0.4	0.9	1.2	-1.1	0.8
Ulcerative Colitis (UC)	0.4	0.8	0.8	-0.9	0.9
Blood White Count	0.4	2.9	5.5	-0.5	2.3
Systolic Blood Pressure	0.4	2.1	4.0	0.5	-2.0
Allergy or Eczema	0.4	0.9	1.3	-1.2	0.7
Number of treatments/medications taken	0.4	0.7	1.0	1.0	-0.6
Waist circumference	0.4	1.6	1.8	1.4	1.2
Nervous feelings	0.4	0.7	1.4	-0.0	1.2
Allergy	0.4	1.0	1.3	1.1	-0.9
Asthma	0.4	0.8	1.2	-0.5	1.1
Depression (self-reported)	0.4	0.4	0.8	-0.3	-0.9
Lung cancer (father)	0.4	0.5	0.6	0.7	0.8
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.0	-0.6	1.0
Glaucoma (self-reported)	0.4	0.4	0.8	0.9	0.3
Number of full brothers	0.4	0.5	0.5	-0.7	0.7
Qualifications: College or University degree	0.4	1.1	2.0	0.5	-1.4
Medication: Allopurinol	0.4	0.5	0.9	0.4	-1.0
Mean time to correctly identify matches	0.4	0.7	0.8	-0.9	-0.8
Had major operations	0.4	0.4	0.6	-0.5	0.8
Leg pain on walking	0.4	0.4	0.5	0.7	-0.7
Whole body fat-free mass	0.4	2.2	4.3	2.1	-0.1
Medication for cholesterol	0.4	0.5	0.9	0.4	-1.0
Osteoarthritis (self-reported)	0.4	0.5	0.9	-1.0	-0.2
Whole body water mass	0.4	2.4	4.7	2.2	-0.2
Basal metabolic rate	0.4	2.2	4.4	2.1	-0.1
Basal cell carcinoma (self-reported)	0.4	0.4	0.7	-0.8	-0.5
Neuroticism (Nagel 2018)	0.3	0.8	1.3	0.5	-1.1
HDL Cholesterol	0.3	0.5	0.5	-0.7	-0.7
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.5	-0.7	-0.6
Vitamin and mineral supplements	0.3	0.5	0.9	-0.9	0.2
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.5	-0.7	-0.2
High blood pressure	0.3	0.9	1.8	-0.0	1.3
Supplements: Glucosamine	0.3	0.4	0.7	-0.8	-0.5
Medication: Atenolol	0.3	0.4	0.8	-0.2	0.9
High blood pressure (mother)	0.3	0.4	0.8	-0.3	0.9
Medication: Simvastatin	0.3	0.4	0.7	0.8	-0.3
Illnesses of siblings	0.3	0.4	0.5	-0.7	-0.6
Weight	0.3	1.6	3.3	1.8	0.2
Hip circumference	0.3	1.2	2.4	1.6	0.0
Medication: Lansoprazole	0.3	0.3	0.6	0.8	0.1
Illnesses of mother	0.3	0.4	0.8	-0.1	-0.9
Pulse wave Arterial Stiffness index	0.3	0.3	0.6	-0.0	-0.8
High blood pressure (siblings)	0.3	0.4	0.8	0.3	0.9
Leg fat percentage (right)	0.3	1.0	2.0	-0.0	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.7	0.9	-0.3
Hypertension (Self-reported)	0.3	0.9	1.7	-0.1	1.3
Leg fat-free mass (right)	0.3	1.6	3.2	1.8	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	0.7	0.8	-0.1
Leg predicted mass (right)	0.3	1.7	3.3	1.8	-0.1
Average weekly champagne plus white wine intake	0.3	0.4	0.8	0.3	-0.9
Guilty feelings	0.3	0.5	0.9	0.9	-0.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.6	-0.5	0.7
High cholesterol (Self-reported)	0.3	0.6	0.9	-1.0	0.5
Age started oral contraceptive pill	0.3	0.3	0.7	-0.0	0.8
Ever depressed for a whole week	0.3	0.4	0.8	0.9	0.2
Leg fat mass (left)	0.3	1.1	1.4	1.2	0.9
Depressed Affect (Nagel 2018)	0.2	0.4	0.6	0.4	-0.8
Depression (Nagel 2018)	0.2	0.3	0.7	-0.8	-0.2
Crohns Disease (2017)	0.2	0.4	0.7	-0.8	0.4
Ulcerative Colitis	0.2	0.3	0.6	-0.8	0.1
Blood Eosinophil Count	0.2	1.5	2.4	-0.8	1.6
BMI	0.2	0.9	1.7	0.4	1.3
Average weekly spirits intake	0.2	0.3	0.6	0.8	-0.0
Medication: Co-codamol	0.2	0.2	0.4	-0.6	-0.3
Diabetes (father)	0.2	0.3	0.4	0.5	-0.6
Diabetes (mother)	0.2	0.3	0.5	0.7	0.3
Severe depression (siblings)	0.2	0.2	0.3	-0.5	-0.3
Leg fat-free mass (left)	0.2	1.0	1.9	1.4	0.1
Townsend deprivation index at recruitment	0.2	0.3	0.6	0.2	0.8
Medication: Levothyroxine sodium	0.2	0.4	0.5	-0.6	0.7
Chronic bronchitis/emphysema (father)	0.2	0.2	0.4	0.2	0.7
Body mass index (BMI)	0.2	0.8	1.5	0.4	1.2
Leg predicted mass (left)	0.2	1.1	2.1	1.5	0.1
Trunk fat mass	0.2	0.8	1.5	1.2	0.3
Hair/balding pattern: Pattern 2	0.2	0.3	0.3	0.5	0.6
Qualifications: None of the above	0.2	0.5	1.0	-1.0	-0.1
Diabetes (self-reported)	0.2	0.2	0.5	-0.0	-0.7
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.3	-0.3	0.6
Worrier / anxious feelings	0.2	0.4	0.4	0.6	-0.6
Noisy workplace	0.2	0.2	0.3	0.5	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.3	-0.5	-0.5
Arm fat mass (right)	0.2	0.7	1.1	1.0	0.5
Loud music exposure frequency	0.2	0.2	0.5	0.0	-0.7
Headache pain in last month	0.2	0.3	0.4	-0.4	0.6
Pulse wave peak to peak time	0.2	0.2	0.2	0.4	0.5
Heart disease (mother)	0.2	0.2	0.4	0.3	0.6
Leg fat mass (right)	0.2	0.9	1.6	0.5	1.2
Family relationship satisfaction	0.2	0.2	0.4	0.6	-0.2
Illnesses of siblings: Diabetes	0.2	0.3	0.6	-0.8	0.1
Commuting to job workplace: Walk	0.2	0.2	0.3	0.3	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.5	0.1	0.7
Asthma (self-reported)	0.2	0.5	0.8	-0.3	0.9
Arm fat mass (left)	0.2	0.6	0.8	0.9	0.7
Mother’s age at death	0.2	0.2	0.2	0.5	0.4
Medication: Paracetamol	0.2	0.3	0.4	-0.5	0.6
Medication: Lisinopril	0.2	0.3	0.5	0.3	0.7
Leg fat percentage (left)	0.2	0.9	1.3	0.7	1.2
Average weekly beer plus cider intake	0.2	0.2	0.4	-0.7	0.1
Irritability	0.2	0.3	0.6	0.8	-0.2
Worry (Nagel 2018)	0.1	0.2	0.3	-0.6	-0.2
Bipolar Disorder (2011)	0.1	0.1	0.2	0.0	0.4
Body Mass Index (BMI) (2010)	0.1	0.1	0.1	0.4	-0.0
Coronary Artery Disease (CAD)	0.1	0.1	0.2	-0.1	0.5
Neuroticism (2016)	0.1	0.1	0.2	-0.5	-0.3
Triglycerides	0.1	0.2	0.4	0.3	-0.6
Blood Platelet Count	0.1	1.2	1.4	-1.2	1.0
Blood Red Count	0.1	0.7	0.9	-0.7	0.9
Cardiovascular Disease	0.1	0.3	0.6	-0.1	0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.4	-0.1	-0.6
Chronotype (morning person)	0.1	0.3	0.6	0.8	0.1
Hair Pigment	0.1	1.9	3.3	-1.8	-0.7
Tanning	0.1	1.1	1.7	-0.6	-1.3
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.2	0.4	0.5
Systolic blood pressure, automated reading	0.1	0.4	0.6	-0.5	-0.7
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	-0.4	-0.0
Trunk fat percentage	0.1	0.3	0.6	0.8	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	0.0	-0.4
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.2	-0.3	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.2	0.3	-0.4
Neuroticism score	0.1	0.2	0.3	0.5	-0.4
Impedance of arm (right)	0.1	0.4	0.7	-0.8	-0.5
Number of live births	0.1	0.2	0.3	0.6	0.0
Impedance of arm (left)	0.1	0.7	1.2	-1.1	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	-0.1	-0.5
Birth weight of first child	0.1	0.1	0.2	0.4	0.1
Blood clot in the leg (DVT)	0.1	0.2	0.3	0.5	-0.2
Gout (self-reported)	0.1	0.2	0.2	-0.5	-0.4
Body fat percentage	0.1	0.2	0.3	0.4	0.5
Wheeze or whistling in the chest in last year	0.1	0.1	0.1	-0.3	0.3
Medication: Blood pressure	0.1	0.1	0.1	0.4	-0.3
Whole body fat mass	0.1	0.6	1.0	1.0	0.5
Comparative height size at age 10	0.1	0.7	0.7	0.8	-0.8
Supplements: Vitamin C	0.1	0.2	0.3	0.0	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.2	0.4	0.3
Arm fat percentage (left)	0.1	0.3	0.6	-0.1	0.8
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.5	-0.1
Ever had bowel cancer screening	0.1	0.1	0.2	-0.3	0.4
Diabetes diagnosed by doctor	0.1	0.2	0.4	-0.1	-0.6
Friendships satisfaction	0.1	0.1	0.2	0.4	0.1
Qualifications: nursing, teaching	0.1	0.1	0.2	0.3	-0.5
Mineral and other dietary supplements	0.1	0.2	0.2	0.4	0.5
Breast cancer (self-reported)	0.1	0.2	0.3	0.5	-0.2
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	0.3	-0.6
Hearing aid user	0.1	0.1	0.1	-0.4	-0.3
Commuting to job workplace: Cycle	0.1	0.1	0.1	-0.2	0.3
Pain experienced in last month	0.1	0.2	0.3	-0.0	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	0.2	-0.4
Heel T-Score	0.0	0.0	0.0	-0.2	-0.0
Smoking Status	0.0	0.0	0.1	0.1	0.2
Neuroticism	0.0	0.1	0.1	0.3	-0.3
Impedance of leg (right)	0.0	0.0	0.0	-0.2	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	-0.4	-0.1
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.0	0.1	0.0
Impedance of leg (left)	0.0	0.1	0.3	0.5	-0.0
Number of incorrect matches in round	0.0	0.1	0.2	-0.1	0.4
Financial difficulties in last 2 years	0.0	0.0	0.1	0.3	0.1
Arm fat percentage (right)	0.0	0.2	0.3	0.2	0.6
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.1	-0.1	-0.2
Prospective memory result	0.0	0.0	0.0	-0.2	-0.1
Hair/balding pattern: Pattern 4	0.0	0.0	0.1	0.1	0.3
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	-0.1	0.0
Mood swings	0.0	0.0	0.0	-0.1	-0.2
Long-standing illness, disability or infirmity	0.0	0.1	0.1	0.3	0.0
Medication: Gliclazide	0.0	0.0	0.1	0.0	-0.3
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	-0.1	0.0
Medication: Bendroflumethiazide	0.0	0.0	0.0	0.2	0.1
Unable to work because of sickness or disability	0.0	0.0	0.0	0.1	-0.1
Myopia	0.0	0.0	0.1	-0.1	-0.3
Impedance of whole body	0.0	0.1	0.1	-0.3	-0.3

Hub : Genes

NGDN

Models

Trait associations