TWAS hub - SLC22A17

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Skin Not Sun Exposed Suprapubic	0.2090	0.060	2.2e-04	0.048	NA	0.026	NA	0.070	1.2e-03	NA	1.4e-02	NA	1.1e-04
2	METSIM	Adipose	0.0922	0.027	9.1e-06	0.091	0.039	0.070	0.086	0.077	1.9e-13	1.6e-06	1.1e-10	9e-13	1.3e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pulse rate, automated reading	61.5	198.8	353.4	18.8	6.7
Pulse rate	37.2	62.7	102.0	10.1	4.8
Pulse wave reflection index	5.7	7.1	14.0	-3.7	-0.3
Neuroticism score	5.0	10.4	20.7	4.5	0.2
Loneliness, isolation	4.7	6.5	13.0	3.6	0.2
Supplements: Calcium	4.5	5.0	5.9	-2.0	2.4
Systolic blood pressure, automated reading	4.3	12.5	24.4	-4.9	-0.8
Chronic bronchitis/emphysema (mother)	4.1	4.8	5.2	2.3	2.1
Current tobacco smoking	4.0	6.6	9.9	3.2	1.8
Suffer from ‘nerves’	3.9	6.1	11.9	3.5	-0.5
Neuroticism	3.8	9.1	18.0	4.2	0.5
Prostate Cancer	3.6	5.1	6.7	2.6	1.9
Alcohol intake frequency.	3.6	8.4	13.5	1.8	3.7
Guilty feelings	3.6	5.4	10.1	3.2	0.9
Smoking status: Current	3.5	5.5	7.8	2.8	1.8
Had menopause	3.4	4.2	8.2	-2.9	0.5
Ever had hysterectomy (womb removed)	3.2	3.6	4.0	2.0	1.8
Alcohol drinker status: Previous	3.2	3.7	6.7	2.6	0.8
Coronary Artery Disease (CAD)	3.1	3.7	6.9	-2.6	-0.8
Frequency of depressed mood in last 2 weeks	3.1	4.3	8.2	2.9	-0.7
Diabetes (father)	2.8	3.4	3.7	-1.8	-1.9
Nervous feelings	2.8	5.2	8.8	3.0	-1.3
Irritable Bowel Disease (IBD)	2.7	6.5	12.5	-0.6	3.5
Financial situation satisfaction	2.7	3.4	6.5	2.6	-0.5
Qualifications: CSEs or equivalent	2.6	3.5	6.8	2.6	0.5
High blood pressure (mother)	2.6	3.6	6.6	-2.6	-0.7
Stomach or abdominal pain in last month	2.5	3.2	5.1	2.2	-1.1
Mood swings	2.5	4.5	8.2	2.9	0.8
Maternal smoking around birth	2.4	3.4	6.8	2.6	0.1
Exposure to tobacco smoke outside home	2.4	3.1	6.0	2.5	-0.5
Ulcerative Colitis (UC)	2.3	4.3	8.3	-0.5	2.9
Waist Hip Ratio (WHR)	2.3	10.4	17.8	4.2	1.7
Financial difficulties in last 2 years	2.3	3.0	3.5	1.9	-1.6
Neuroticism (Nagel 2018)	2.2	5.2	10.3	3.2	0.1
Systolic Blood Pressure	2.2	11.2	20.7	-4.5	-1.3
Tense / ‘highly strung’	2.2	3.7	6.2	2.5	-1.1
Depressed Affect (Nagel 2018)	2.1	4.5	8.0	2.8	1.0
Crohns Disease (2012)	2.1	3.3	4.9	-1.3	2.2
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	2.8	1.7	1.5
Worry too long after embarrassment	2.1	3.6	4.4	1.7	-2.1
Friendships satisfaction	2.1	2.6	5.1	2.3	0.2
Eye problems/disorders: Cataract	2.1	2.4	3.3	1.2	1.8
Average weekly beer plus cider intake	2.1	3.1	4.2	2.0	-1.4
Diastolic blood pressure, automated reading	2.1	6.6	6.9	2.6	2.5
Pack years adult smoking proportion	2.0	3.1	4.2	2.1	1.4
Multivitamins +/- minerals	2.0	2.5	4.1	1.0	2.0
Medication: Ventolin 100micrograms inhaler	2.0	2.5	2.9	-1.7	-1.5
Medication: Omeprazole	2.0	2.3	4.5	2.1	0.4
Age started oral contraceptive pill	2.0	2.5	4.7	-2.2	0.5
Unable to work because of sickness or disability	2.0	2.6	4.7	2.2	0.7
Worry (Nagel 2018)	1.9	3.9	7.4	2.7	-0.6
Crohns Disease (2017)	1.9	4.1	7.8	-0.7	2.8
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.0	3.7	1.9	1.5
Pulse wave Arterial Stiffness index	1.9	2.3	4.2	-0.6	2.0
Hair/balding pattern: Pattern 4	1.9	4.5	6.2	-2.5	-1.7
Illnesses of father: None of the above (group 1)	1.9	2.3	3.1	1.2	1.8
Myopia	1.9	2.7	4.0	2.0	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	4.7	2.2	0.1
Medication: Ramipril	1.8	2.3	3.2	1.2	1.8
Health satisfaction	1.8	2.3	4.0	2.0	0.8
Fed-up feelings	1.7	3.1	6.0	2.4	0.4
Hair/balding pattern: Pattern 3	1.7	2.5	4.2	-2.0	1.0
Qualifications: A levels/AS levels or equivalent	1.7	3.7	5.6	-1.3	-2.4
Long-standing illness, disability or infirmity	1.7	2.6	5.2	2.3	-0.1
Lung FEV1/FVC ratio	1.6	8.2	16.3	-4.0	-0.2
Pulse wave peak to peak time	1.6	1.9	3.4	0.5	-1.9
Medication: Seretide 50 evohaler	1.6	1.9	2.0	1.3	1.4
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	3.8	-0.3	1.9
Medication: Gliclazide	1.6	1.8	3.2	1.8	0.6
Average weekly spirits intake	1.5	1.9	2.6	1.1	-1.6
Sensitivity / hurt feelings	1.5	2.5	5.0	2.2	0.3
Alcohol intake versus 10 years previously	1.5	2.3	3.4	1.1	1.8
Peak expiratory flow (PEF)	1.5	3.6	4.3	1.7	2.1
Blood clot in the leg (DVT)	1.5	1.9	3.8	0.0	1.9
Family relationship satisfaction	1.5	1.9	2.3	1.2	1.5
Supplements: Fish oil (including cod liver oil)	1.5	2.0	3.8	-2.0	-0.4
Irritability	1.5	2.6	5.0	2.2	0.4
Risk taking	1.5	2.2	3.4	-1.9	-1.0
Forced vital capacity (FVC)	1.4	5.4	6.5	2.5	2.1
Pain all over the body in last month	1.4	1.5	1.8	1.1	1.3
Medication: Allopurinol	1.4	1.9	2.1	-1.4	1.3
Number of full sisters	1.4	1.7	2.2	1.5	1.1
Overall health rating	1.4	2.9	4.8	2.2	1.0
Heart attack/myocardial infarction (self-reported)	1.4	1.8	2.2	1.5	1.2
Diabetes (mother)	1.3	1.7	2.7	0.8	-1.6
Chronic bronchitis/emphysema (father)	1.3	1.5	1.5	1.2	1.2
Qualifications: College or University degree	1.3	4.2	6.5	-2.6	-1.4
Average weekly red wine intake	1.3	1.9	3.7	-1.9	0.4
Back pain experienced in last month	1.3	1.9	3.2	0.8	1.8
Illnesses of father: High blood pressure	1.3	1.6	1.8	-1.2	-1.3
Pack years of smoking	1.3	1.9	2.1	1.3	1.4
Depression (Nagel 2018)	1.2	1.9	3.7	1.9	-0.1
Breast Cancer	1.2	2.9	3.1	-1.8	-1.7
Mouth/teeth dental problems	1.2	1.9	2.2	-1.2	-1.5
Headache pain in last month	1.2	2.0	3.1	1.8	0.9
Birth weight	1.2	2.5	3.8	1.9	1.1
Forced vital capacity (FVC), Best measure	1.2	4.2	4.6	2.1	2.0
Commuting to job workplace: Car/motor vehicle	1.2	1.3	2.6	0.0	1.6
Illnesses of father: Heart disease	1.2	1.7	1.8	-1.3	-1.3
Handedness (chirality/laterality): Left-handed	1.2	1.4	2.6	-1.6	-0.4
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	3.1	-0.1	1.8
Schizophrenia (2018)	1.1	2.4	2.7	-1.6	-1.4
Schizophrenia vs Biploar Disorder	1.1	1.4	2.7	-1.7	-0.3
Blood Eosinophil Count	1.1	8.5	16.3	-4.0	0.9
Hearing difficulty/problems: Yes	1.1	1.7	3.3	-1.8	0.3
Medication: Co-codamol	1.1	1.3	2.0	-1.4	-0.7
Townsend deprivation index at recruitment	1.1	1.6	2.7	1.6	0.7
Noisy workplace	1.1	1.3	2.6	-1.6	0.1
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	2.3	0.6	-1.5
Supplements: Vitamin C	1.1	1.3	2.2	-1.5	-0.6
Osteoporosis (self-reported)	1.1	1.4	2.7	-0.4	-1.6
Average weekly champagne plus white wine intake	1.1	1.5	3.0	-1.7	0.0
Schizophrenia (2014)	1.0	2.3	2.4	-1.5	-1.6
Type 2 Diabetes (T2D) (2018)	1.0	1.8	3.4	1.9	0.5
Alcohol usually taken with meals	1.0	1.7	3.2	-0.4	1.8
Heart attack	1.0	1.3	1.4	1.2	1.1
Illnesses of siblings	1.0	1.4	1.9	1.4	0.9
Hip circumference	1.0	4.1	4.5	-1.9	2.1
Number of live births	1.0	1.4	2.6	1.6	0.4
Impedance of arm (left)	1.0	4.7	9.3	3.1	0.2
Length of working week for main job	1.0	1.2	2.0	1.4	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	1.4	-1.2	-1.1
Shortness of breath walking on level ground	1.0	1.2	1.7	1.3	-0.9
Mouth/teeth dental problems: Loose teeth	1.0	1.2	1.9	0.7	1.4
Comparative height size at age 10	1.0	5.3	7.7	1.7	2.8
Knee pain experienced in last month	1.0	1.6	2.8	-1.7	-0.7
Pain type(s) experienced in last month: Hip pain	1.0	1.3	1.6	1.3	1.0
Fractured/broken bones in last 5 years	1.0	1.3	1.6	1.3	1.0
Ulcerative Colitis	0.9	1.3	2.5	-0.3	1.6
Waist circumference	0.9	3.3	6.3	0.6	2.5
Number of incorrect matches in round	0.9	1.5	3.0	-0.1	1.7
Happiness	0.9	1.1	2.0	1.4	0.4
Medication: Lansoprazole	0.9	1.0	2.0	-0.0	-1.4
Ever highly irritable/argumentative for 2 days	0.9	1.1	1.1	1.0	1.0
Wheeze or whistling in the chest in last year	0.9	1.7	2.0	1.4	1.2
Medication: Blood pressure	0.9	1.6	1.8	-1.2	1.3
Miserableness	0.9	1.5	2.9	1.7	0.2
Commuting to job workplace: Public transport	0.9	1.1	1.6	-1.2	-0.8
Alzheimer’s Disease (in father)	0.8	0.9	1.3	-0.7	1.1
Rheumatoid Arthritis	0.8	1.1	1.8	-1.4	-0.7
Triglycerides	0.8	1.4	2.8	0.1	1.7
Lung FVC	0.8	4.2	7.6	2.7	0.9
Chronotype (morning person)	0.8	1.8	3.3	0.5	1.8
Serious illness, injury or assault to yourself	0.8	0.9	1.8	0.2	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	2.1	1.4	-1.2
Worrier / anxious feelings	0.8	1.4	2.6	1.6	0.5
Illnesses of mother	0.8	1.0	1.7	1.3	0.5
Medication: Amlodipine	0.8	1.1	1.9	-0.4	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.4	-1.2	-0.6
Angina (self-reported)	0.8	1.0	1.9	-0.4	1.4
Medication: Ibuprofen	0.8	0.9	1.6	0.4	-1.3
Chest pain or discomfort	0.8	1.2	2.4	1.6	-0.2
Mineral and other dietary supplements	0.8	1.1	2.0	1.4	-0.3
Basal cell carcinoma (self-reported)	0.8	1.0	1.6	-1.3	-0.6
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.6	1.3	0.2
Severe depression (siblings)	0.7	0.8	0.9	0.9	0.8
Trunk fat percentage	0.7	3.0	5.4	0.7	2.3
Trunk fat mass	0.7	3.1	6.1	0.3	2.5
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.1	1.4	-0.2
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	3.0	1.4	1.7
Body fat percentage	0.7	2.8	5.4	0.4	2.3
Medication for pain relief, constipation, heartburn	0.7	1.2	2.3	-1.5	0.3
Migraine (self-reported)	0.7	0.8	1.6	0.3	-1.2
Medication: Aspirin	0.7	0.9	1.6	-0.4	1.3
Qualifications: nursing, teaching	0.7	1.0	2.1	1.4	-0.1
Medication: Aspirin	0.7	0.9	1.3	-0.7	1.1
Medication: Bendroflumethiazide	0.7	1.1	2.1	-0.2	1.4
Alcohol drinker status: Never	0.7	0.9	1.7	-0.2	1.3
Heart disease (siblings)	0.7	0.8	1.5	-1.2	-0.3
Impedance of whole body	0.7	3.8	7.6	2.8	0.2
Leg fat mass (left)	0.7	2.7	5.0	-0.6	2.2
Alzheimer’s Disease (including proxy)	0.6	0.8	1.5	0.4	1.2
HbA1C	0.6	0.7	0.9	1.0	0.7
Lupus	0.6	0.8	1.7	0.2	1.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.2	0.6	1.1
Angina	0.6	0.8	1.3	-0.6	1.2
Medication: Metformin	0.6	0.8	1.5	1.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	2.6	0.1	-1.6
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	0.8	0.8	0.9
Weight	0.6	2.8	5.4	-0.5	2.3
Mouth/teeth dental problems: Dentures	0.6	1.0	1.9	0.0	1.4
Gout (self-reported)	0.6	0.8	1.5	-1.2	0.1
Number of full brothers	0.6	0.7	1.3	-0.4	-1.1
Neck or shoulder pain in last month	0.6	0.9	1.7	1.3	-0.4
Mean time to correctly identify matches	0.6	1.1	2.1	-0.3	-1.5
Whole body fat mass	0.6	2.7	5.3	0.1	2.3
Leg fat mass (right)	0.6	2.2	4.1	-0.6	2.0
Age at last live birth	0.6	0.8	0.9	-0.9	0.9
Diabetes diagnosed by doctor	0.6	1.0	1.9	1.4	0.3
Osteoarthritis (self-reported)	0.6	0.8	1.4	-0.4	-1.2
Medication: Paracetamol	0.6	1.0	2.0	-0.1	-1.4
Cholesterol lowering medication	0.6	0.8	1.7	-0.0	1.3
Alzheimer’s Disease (in mother)	0.5	0.6	0.6	0.8	0.8
Mean Putamen Volume	0.5	0.6	1.2	0.1	-1.1
HDL Cholesterol	0.5	0.8	1.3	-1.2	-0.5
Smoking Status	0.5	1.2	2.0	1.4	0.6
Relative age of first facial hair	0.5	1.1	2.1	-0.4	1.4
Supplements: Zinc	0.5	0.5	0.9	-0.4	0.9
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.6	-0.7	0.8
Hearing difficulty/problems with background noise	0.5	0.9	1.6	-1.3	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.1	-1.0	-0.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.2	1.1	-0.0
Medication: Paracetamol	0.5	0.9	1.2	1.1	-0.8
Glaucoma (self-reported)	0.5	0.6	0.9	1.0	0.5
High blood pressure (siblings)	0.5	0.7	1.3	-1.1	0.1
Arm fat-free mass (right)	0.5	2.4	4.0	-0.9	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.0	1.0	0.5
Smoking status: Previous	0.5	0.8	0.8	-0.9	-0.8
Ever had bowel cancer screening	0.5	0.6	0.8	-0.7	0.9
Eye problems/disorders: Glaucoma	0.5	0.6	0.9	0.9	-0.5
Number of operations (self-reported)	0.5	0.8	1.6	1.3	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	0.9	1.0	0.5
Bipolar Disorder or Schizophrenia	0.4	0.9	1.2	-1.1	-0.8
Age at First Birth	0.4	0.6	1.2	-1.1	-0.1
Hair/balding pattern: Pattern 2	0.4	0.6	1.1	0.2	1.1
Had other major operations	0.4	0.5	0.8	0.9	0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	0.9	-1.0	-0.4
Impedance of arm (right)	0.4	2.0	3.9	2.0	-0.3
Falls in the last year	0.4	0.6	1.1	1.0	-0.2
Lung cancer (father)	0.4	0.4	0.7	-0.9	-0.3
Arm fat mass (right)	0.4	1.6	2.8	-0.5	1.7
Standing height	0.4	3.5	6.3	0.8	2.5
Breastfed as a baby	0.4	0.4	0.9	0.2	0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.2	0.3	-1.1
Arm predicted mass (right)	0.4	2.1	3.9	-0.4	2.0
Illnesses of siblings: Diabetes	0.4	0.5	1.0	-0.1	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.1	1.1	0.8
Arm fat percentage (left)	0.4	1.4	2.8	-0.0	1.7
Arm fat mass (left)	0.4	1.7	3.3	-0.2	1.8
Leg fat percentage (left)	0.4	1.3	2.6	-0.1	1.6
Arm fat-free mass (left)	0.4	1.9	3.1	-0.9	1.7
Arm predicted mass (left)	0.4	2.0	2.6	-1.2	1.6
Ovarian Cancer	0.3	0.4	0.7	0.8	-0.2
Blood Platelet Count	0.3	3.6	7.2	-2.7	0.1
Blood White Count	0.3	1.9	3.7	-0.4	1.9
Cardiovascular Disease	0.3	0.9	1.7	-1.3	-0.3
Leg fat-free mass (left)	0.3	1.4	2.6	-0.4	1.6
Supplements: Glucosamine	0.3	0.4	0.7	-0.9	0.0
Medication: Atenolol	0.3	0.3	0.5	-0.4	0.7
Medication: Levothyroxine sodium	0.3	0.4	0.7	-0.4	0.9
Sitting height	0.3	1.8	3.5	-1.9	0.3
Body mass index (BMI)	0.3	1.3	1.7	-1.0	1.3
Diabetes (self-reported)	0.3	0.4	0.6	0.8	0.5
Arm fat percentage (right)	0.3	1.4	2.3	-0.6	1.5
Time employed in main current job	0.3	0.3	0.6	-0.2	-0.8
Depression (self-reported)	0.3	0.4	0.7	0.1	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	1.1	0.8	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.6	0.8	-0.7
Comparative body size at age 10	0.3	0.7	1.5	-0.1	1.2
Number of children fathered	0.3	0.3	0.7	0.1	-0.8
Eye problems/disorders: None of the above	0.3	0.3	0.6	-0.2	-0.8
Emphysema/chronic bronchitis	0.3	0.4	0.6	0.8	0.3
Leg pain on walking	0.3	0.3	0.4	-0.5	-0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.7	0.4	0.8
Hypertension (Self-reported)	0.3	0.9	1.2	-1.1	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.5	-0.4	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.4	0.5	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.2	-0.2	1.1
Wears glasses or contact lenses	0.3	0.4	0.8	-0.1	0.9
Mother’s age at death	0.3	0.4	0.8	0.1	-0.9
Medication: Lisinopril	0.3	0.4	0.6	-0.8	0.4
Basal metabolic rate	0.3	1.6	2.9	-0.5	1.7
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.1	1.0	-0.6
Major Depression (MDD)	0.2	0.2	0.4	0.0	0.6
Reaction Time	0.2	0.4	0.8	-0.2	-0.9
LDL Cholesterol	0.2	0.3	0.3	-0.6	0.5
Primary Biliary Cirrhosis	0.2	0.3	0.4	0.6	0.4
Hypothyroidism (self reported)	0.2	0.5	1.0	0.3	1.0
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.3	-0.5	0.6
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	0.3	0.6
Vitamin and mineral supplements	0.2	0.2	0.5	0.0	-0.7
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.6	-0.8	-0.1
High blood pressure	0.2	0.5	0.8	-0.9	0.4
Impedance of leg (left)	0.2	1.1	2.2	1.5	-0.2
Leg predicted mass (left)	0.2	1.2	2.1	-0.4	1.5
Fluid intelligence score	0.2	0.4	0.6	0.5	0.8
Trunk fat-free mass	0.2	1.3	1.5	-1.1	1.2
Father’s age at death	0.2	0.3	0.3	-0.4	-0.6
Trunk predicted mass	0.2	1.2	1.4	-1.0	1.2
Exposure to tobacco smoke at home	0.2	0.2	0.4	0.2	0.6
Loud music exposure frequency	0.2	0.2	0.3	-0.4	0.6
Leg fat percentage (right)	0.2	0.9	1.6	-0.4	1.3
Age at first live birth	0.2	0.3	0.4	0.4	0.6
Heart disease (mother)	0.2	0.3	0.5	-0.2	-0.7
Whole body fat-free mass	0.2	1.3	2.1	-0.8	1.4
Leg fat-free mass (right)	0.2	1.1	2.1	-0.1	1.5
Commuting to job workplace: Walk	0.2	0.2	0.2	0.5	-0.3
Breast cancer (self-reported)	0.2	0.2	0.4	-0.6	0.3
Asthma (self-reported)	0.2	0.3	0.4	-0.6	-0.5
Whole body water mass	0.2	1.4	2.4	-0.7	1.5
Leg predicted mass (right)	0.2	1.1	2.3	-0.0	1.5
Hearing aid user	0.2	0.2	0.4	-0.0	0.7
High cholesterol (Self-reported)	0.2	0.3	0.6	-0.8	-0.3
Ever smoked	0.2	0.4	0.7	0.8	0.3
Commuting to job workplace: Cycle	0.2	0.2	0.4	0.0	-0.6
Bipolar Disorder (2018)	0.1	0.2	0.2	0.3	0.5
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.3	-0.6	-0.1
Body Mass Index (BMI) (2010)	0.1	0.2	0.4	-0.6	-0.1
Neuroticism (2016)	0.1	0.2	0.2	0.4	-0.4
Blood Red Count	0.1	1.2	1.3	1.0	1.2
Heel T-Score	0.1	0.7	0.9	-1.0	-0.7
Height	0.1	1.1	2.1	0.0	1.5
Allergy or Eczema	0.1	0.3	0.7	-0.8	0.1
Respiratory disease	0.1	0.2	0.2	-0.3	-0.5
Hair Pigment	0.1	2.3	2.7	1.6	1.4
Hand grip strength (left)	0.1	0.2	0.2	-0.4	0.4
Medication for hormone replacement therapy	0.1	0.1	0.2	0.4	-0.3
Impedance of leg (right)	0.1	0.6	1.0	1.0	-0.5
Hand grip strength (right)	0.1	0.4	0.8	0.9	0.2
Average weekly fortified wine intake	0.1	0.1	0.1	-0.1	0.4
Relative age voice broke	0.1	0.2	0.4	-0.6	-0.1
Taking other prescription medications	0.1	0.2	0.4	-0.2	0.6
Age when periods started (menarche)	0.1	0.4	0.7	-0.8	-0.2
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.5	-0.7	-0.3
Past tobacco smoking	0.1	0.1	0.2	-0.0	0.4
Medication: Simvastatin	0.1	0.1	0.1	-0.4	0.2
Asthma	0.1	0.2	0.4	-0.3	-0.6
Prospective memory result	0.1	0.1	0.2	-0.5	0.1
Birth weight of first child	0.1	0.1	0.2	0.5	-0.0
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.2	0.5	-0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.2	0.1	0.5
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.2	0.4	0.4
Medication for cholesterol	0.1	0.2	0.2	0.3	-0.4
Number of self-reported non-cancer illnesses	0.1	0.2	0.5	-0.1	0.7
Ever taken oral contraceptive pill	0.1	0.1	0.3	-0.0	-0.5
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	-0.3	-0.3
Ever depressed for a whole week	0.1	0.1	0.1	0.2	-0.3
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.1	-0.3	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.0	0.1	0.1	0.2	-0.3
BMI	0.0	0.2	0.4	-0.1	0.6
Tanning	0.0	0.5	0.6	-0.8	0.6
Number of treatments/medications taken	0.0	0.1	0.1	0.1	-0.3
Qualifications: None of the above	0.0	0.1	0.1	0.3	0.1
Allergy	0.0	0.1	0.2	0.4	-0.1
Medication: Cholesterol lowering	0.0	0.1	0.1	0.3	0.2
Had major operations	0.0	0.0	0.1	-0.0	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.1	-0.3	-0.1
Medication: Blood pressure	0.0	0.0	0.1	0.0	0.3
Medication: Atorvastatin	0.0	0.0	0.0	-0.2	-0.1
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.1	0.3	0.0
Pain experienced in last month	0.0	0.1	0.1	-0.2	-0.3

Hub : Genes

SLC22A17

Models

Trait associations