Hub : Traits :

Nervous feelings

627 significantly associated models · 120 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 3 49598064 51234774 6 1 9.6e-08 7.8e-08 1.0e+00 100 U73166.2
2 3 51616334 53778875 11 1 1.8e-08 8.9e-08 1.7e-01 93 GNL3
3 3 84317575 86808226 1 1 1.8e-15 3.1e-17 2.7e-05 75 CADM2
4 3 135273949 137261517 3 1 1.0e-10 5.1e-10 5.4e-01 99 RP11-85F14.5
5 5 92808753 94615316 1 1 2.4e-09 2.4e-08 1.0e+00 100 KIAA0825
6 6 25296606 26689223 1 1 9.8e-08 1.1e-06 6.1e-03 68 U91328.19
7 6 89108830 90520848 1 1 2.1e-07 1.6e-05 2.3e-01 92 SRSF12
8 7 6502367 7988091 1 1 7.0e-08 1.8e-08 5.4e-02 88 C1GALT1
9 10 103550604 105647095 5 3 9.2e-09 1.9e-10 7.9e-01 100 CNNM2 CYP17A1-AS1 NT5C2
10 11 46499874 48028343 2 2 6.7e-09 2.0e-07 6.9e-01 99 MADD PACSIN3
11 14 74424938 76089054 4 1 5.8e-11 2.4e-09 5.0e-01 99 AREL1
12 16 28825605 31860399 19 2 4.5e-11 5.5e-10 4.2e-01 98 INO80E KAT8
13 17 1263564 2939981 3 1 5.0e-10 5.5e-07 5.5e-03 69 SRR
14 17 4488884 6031861 2 1 4.2e-08 4.4e-08 1.0e+00 100 RPAIN
15 17 42607368 45796313 21 1 2.3e-11 1.3e-10 1.0e+00 100 LRRC37A4P
16 20 32594714 34225302 3 1 3.6e-09 1.5e-08 3.1e-02 85 TP53INP2
17 22 40903421 42301748 1 1 3.4e-07 1.9e-06 1.5e-01 91 L3MBTL2

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (in mother) 2.3 1 0 0.0 0.00 1.0e+00 KAT8
Alzheimer’s Disease (including proxy) 4.1 2 1 3.0 0.00 1.0e+00 KAT8 MADD
Major Depression (MDD) 3.8 1 0 0.0 0.00 1.0e+00 CNNM2
Verbal and Numeric Reasoning (VNR) 2.3 2 1 3.0 0.00 1.0e+00 GNL3 LRRC37A4P
Breast Cancer 2.1 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Ovarian Cancer 2.8 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Bipolar Disorder 4.5 1 0 0.0 0.00 1.0e+00 GNL3
Body Mass Index (BMI) (2010) 4.1 3 0 0.0 0.00 1.0e+00 CNNM2 MADD RPAIN
Coronary Artery Disease (CAD) 3.2 2 0 0.0 0.00 1.0e+00 CNNM2 CYP17A1-AS1
Fasting Glucose 3.2 2 1 3.0 0.00 1.0e+00 MADD PACSIN3
Neuroticism 6.7 4 1 3.0 -1.00 1.4e-03 AREL1 LRRC37A4P MADD U73166.2
Primary Biliary Cirrhosis 1.7 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Schizophrenia 6.3 7 5 15.2 -0.99 4.7e-05 CNNM2 CYP17A1-AS1 GNL3 INO80E L3MBTL2 NT5C2 RP11-85F14.5
Triglycerides 2.4 2 2 6.1 0.00 1.0e+00 KAT8 TP53INP2
Blood Eosinophil Count 2.0 5 4 12.1 -0.01 9.8e-01 INO80E KAT8 L3MBTL2 LRRC37A4P SRSF12
Blood Platelet Count 1.6 9 8 24.2 0.64 6.2e-02 AREL1 GNL3 LRRC37A4P MADD NT5C2 PACSIN3 RP11-85F14.5 RPAIN U73166.2
Blood Red Count 4.5 6 6 18.2 -0.90 1.4e-02 CNNM2 CYP17A1-AS1 GNL3 INO80E KAT8 LRRC37A4P
Blood White Count 1.9 6 3 9.1 0.59 2.2e-01 CNNM2 LRRC37A4P MADD NT5C2 RP11-85F14.5 RPAIN
Heel T-Score 2.6 9 6 18.2 -0.12 7.6e-01 AREL1 CNNM2 CYP17A1-AS1 INO80E KAT8 L3MBTL2 LRRC37A4P MADD PACSIN3
BMI 5.7 10 10 30.3 0.84 2.4e-03 CADM2 CNNM2 CYP17A1-AS1 GNL3 INO80E KAT8 MADD RPAIN SRR SRSF12
Height 1.8 10 8 24.2 0.46 1.8e-01 AREL1 CYP17A1-AS1 GNL3 INO80E KAT8 LRRC37A4P MADD NT5C2 TP53INP2 U73166.2
Waist Hip Ratio (WHR) 2.7 4 4 12.1 -0.54 4.6e-01 GNL3 LRRC37A4P RP11-85F14.5 U73166.2
Systolic Blood Pressure 7.2 8 7 21.2 -0.66 7.4e-02 AREL1 CADM2 CNNM2 CYP17A1-AS1 LRRC37A4P MADD NT5C2 SRR
Smoking Status 4.8 5 3 9.1 0.97 4.8e-03 CADM2 CYP17A1-AS1 GNL3 NT5C2 SRR
Allergy or Eczema 2.0 2 0 0.0 0.00 1.0e+00 L3MBTL2 SRR
Cardiovascular Disease 3.5 4 3 9.1 0.91 9.0e-02 CNNM2 CYP17A1-AS1 KAT8 RP11-85F14.5
Lung FEV1/FVC ratio 1.8 4 1 3.0 0.55 4.5e-01 AREL1 C1GALT1 INO80E LRRC37A4P
Lung FVC 3.8 5 3 9.1 0.52 3.7e-01 CYP17A1-AS1 KAT8 LRRC37A4P TP53INP2 U73166.2
Neuroticism 11.7 14 8 24.2 -0.96 2.7e-08 AREL1 CADM2 CNNM2 CYP17A1-AS1 GNL3 KAT8 L3MBTL2 LRRC37A4P MADD NT5C2 RP11-85F14.5 SRSF12 TP53INP2 U73166.2
Chronotype (morning person) 2.2 2 1 3.0 0.00 1.0e+00 SRSF12 U73166.2
Hair Pigment 7.1 3 2 6.1 0.00 1.0e+00 L3MBTL2 LRRC37A4P TP53INP2
Tanning 14.0 4 2 6.1 0.63 3.7e-01 AREL1 CADM2 GNL3 TP53INP2
Hand grip strength (left) 4.5 7 3 9.1 -0.27 5.5e-01 AREL1 CADM2 CYP17A1-AS1 INO80E KAT8 LRRC37A4P MADD
Number of treatments/medications taken 2.9 1 1 3.0 0.00 1.0e+00 AREL1
Sensitivity / hurt feelings 5.6 2 1 3.0 0.00 1.0e+00 LRRC37A4P RP11-85F14.5
Frequency of depressed mood in last 2 weeks 5.1 4 0 0.0 -0.78 2.2e-01 LRRC37A4P MADD RP11-85F14.5 U73166.2
Hearing difficulty/problems: Yes 2.0 1 0 0.0 0.00 1.0e+00 KIAA0825
Relative age of first facial hair 4.0 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Systolic blood pressure, automated reading 5.8 7 4 12.1 0.64 1.2e-01 AREL1 CNNM2 CYP17A1-AS1 LRRC37A4P MADD NT5C2 SRR
Vitamin and mineral supplements 2.4 1 0 0.0 0.00 1.0e+00 U91328.19
Diabetes (father) 1.7 1 0 0.0 0.00 1.0e+00 INO80E
Impedance of leg (right) 4.7 12 7 21.2 0.80 1.8e-03 AREL1 CADM2 CNNM2 CYP17A1-AS1 GNL3 INO80E KAT8 LRRC37A4P MADD PACSIN3 TP53INP2 U73166.2
Leg fat-free mass (left) 5.5 11 9 27.3 -0.96 3.1e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 PACSIN3 RPAIN SRSF12 TP53INP2 U91328.19
Trunk fat percentage 4.8 8 6 18.2 -0.68 6.1e-02 AREL1 INO80E KAT8 LRRC37A4P MADD RPAIN SRR U91328.19
Hand grip strength (right) 3.2 4 2 6.1 -0.55 4.5e-01 CYP17A1-AS1 INO80E LRRC37A4P MADD
Fed-up feelings 4.2 4 3 9.1 0.99 5.1e-03 AREL1 LRRC37A4P MADD RP11-85F14.5
Frequency of unenthusiasm / disinterest in last 2 weeks 3.6 2 0 0.0 0.00 1.0e+00 RP11-85F14.5 U73166.2
Relative age voice broke 3.2 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Taking other prescription medications 2.9 1 1 3.0 0.00 1.0e+00 AREL1
Age when periods started (menarche) 3.4 3 1 3.0 0.00 1.0e+00 INO80E LRRC37A4P MADD
Heel bone mineral density (BMD) T-score, automated (left) 2.5 2 1 3.0 0.00 1.0e+00 L3MBTL2 U91328.19
High blood pressure 4.1 4 4 12.1 -0.84 1.6e-01 CNNM2 CYP17A1-AS1 KAT8 MADD
Hayfever, allergic rhinitis or eczema 2.9 2 1 3.0 0.00 1.0e+00 SRR U91328.19
Medication: Levothyroxine sodium 1.8 1 1 3.0 0.00 1.0e+00 U91328.19
Sitting height 2.5 7 5 15.2 -0.49 2.7e-01 GNL3 INO80E LRRC37A4P MADD NT5C2 TP53INP2 U91328.19
High blood pressure (mother) 3.5 2 1 3.0 0.00 1.0e+00 CNNM2 CYP17A1-AS1
Body mass index (BMI) 5.6 11 7 21.2 -0.84 1.1e-03 CADM2 CNNM2 CYP17A1-AS1 GNL3 INO80E KAT8 MADD RPAIN SRR SRSF12 U91328.19
Impedance of leg (left) 4.6 12 8 24.2 0.81 1.5e-03 AREL1 CADM2 CNNM2 CYP17A1-AS1 GNL3 INO80E LRRC37A4P MADD PACSIN3 SRSF12 TP53INP2 U73166.2
Leg predicted mass (left) 5.4 11 9 27.3 -0.96 2.9e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 PACSIN3 RPAIN SRSF12 TP53INP2 U91328.19
Trunk fat mass 5.6 11 6 18.2 -0.79 4.1e-03 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 LRRC37A4P MADD RPAIN SRR SRSF12 U91328.19
Waist circumference 5.8 9 5 15.2 -0.94 1.8e-04 CADM2 CYP17A1-AS1 INO80E KAT8 MADD RP11-85F14.5 RPAIN SRSF12 U91328.19
Number of incorrect matches in round 4.0 2 1 3.0 0.00 1.0e+00 INO80E KAT8
Past tobacco smoking 4.7 4 2 6.1 1.00 3.6e-03 CADM2 CYP17A1-AS1 NT5C2 SRR
Alcohol usually taken with meals 2.2 1 0 0.0 0.00 1.0e+00 SRR
Frequency of tenseness / restlessness in last 2 weeks 7.2 5 1 3.0 0.79 1.1e-01 CNNM2 LRRC37A4P MADD RP11-85F14.5 TP53INP2
Hearing difficulty/problems with background noise 3.7 3 0 0.0 0.00 1.0e+00 KIAA0825 LRRC37A4P U91328.19
Hair/balding pattern: Pattern 2 2.5 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Forced vital capacity (FVC) 2.6 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Heel bone mineral density (BMD) T-score, automated (right) 2.3 2 0 0.0 0.00 1.0e+00 L3MBTL2 U91328.19
Ever unenthusiastic/disinterested for a whole week 3.3 2 0 0.0 0.00 1.0e+00 LRRC37A4P U73166.2
Allergy 2.4 2 1 3.0 0.00 1.0e+00 SRR U91328.19
Hayfever/allergic rhinitis (self-reported) 2.2 1 0 0.0 0.00 1.0e+00 U91328.19
Fluid intelligence score 2.2 2 0 0.0 0.00 1.0e+00 GNL3 MADD
Neuroticism score 10.8 9 6 18.2 0.95 6.8e-05 AREL1 CADM2 CYP17A1-AS1 L3MBTL2 LRRC37A4P MADD RP11-85F14.5 TP53INP2 U73166.2
Weight 6.2 11 8 24.2 -0.94 2.1e-05 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 MADD NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Impedance of arm (right) 3.7 7 6 18.2 0.71 7.3e-02 CADM2 GNL3 INO80E LRRC37A4P RPAIN TP53INP2 U73166.2
Arm fat percentage (right) 5.0 8 5 15.2 -0.81 1.5e-02 CNNM2 INO80E KAT8 MADD RPAIN SRR SRSF12 U91328.19
Trunk fat-free mass 4.5 10 8 24.2 -0.96 7.4e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Hip circumference 6.2 9 7 21.2 -0.92 5.2e-04 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 MADD RPAIN SRSF12 U91328.19
Worrier / anxious feelings 10.9 13 8 24.2 0.99 3.9e-10 AREL1 C1GALT1 CADM2 CNNM2 CYP17A1-AS1 GNL3 INO80E KAT8 L3MBTL2 LRRC37A4P NT5C2 RP11-85F14.5 U73166.2
Hair/balding pattern: Pattern 3 4.0 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Number of live births 2.0 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Forced expiratory volume in 1-second (FEV1) 2.9 2 1 3.0 0.00 1.0e+00 KAT8 LRRC37A4P
Qualifications: A levels/AS levels or equivalent 1.5 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Mouth/teeth dental problems: Dentures 3.4 2 1 3.0 0.00 1.0e+00 TP53INP2 U91328.19
Medication: Ibuprofen (e.g. Nurofen) 2.2 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Forced expiratory volume in 1-second (FEV1), Best measure 2.7 2 2 6.1 0.00 1.0e+00 KAT8 LRRC37A4P
Impedance of arm (left) 3.8 8 6 18.2 0.72 4.5e-02 CADM2 CYP17A1-AS1 GNL3 INO80E LRRC37A4P RPAIN TP53INP2 U73166.2
Arm fat mass (right) 5.9 10 6 18.2 -0.81 4.6e-03 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 MADD RPAIN SRR SRSF12 U91328.19
Trunk predicted mass 4.5 10 8 24.2 -0.96 8.1e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Standing height 1.9 8 8 24.2 -0.51 1.9e-01 CYP17A1-AS1 GNL3 INO80E LRRC37A4P MADD NT5C2 TP53INP2 U91328.19
Tense / 'highly strung' 9.2 9 3 9.1 0.99 3.8e-08 AREL1 CADM2 CNNM2 INO80E KAT8 RP11-85F14.5 RPAIN TP53INP2 U73166.2
Seen doctor (GP) for nerves, anxiety, tension or depression 2.9 1 0 0.0 0.00 1.0e+00 AREL1
Hair/balding pattern: Pattern 4 6.0 2 2 6.1 0.00 1.0e+00 LRRC37A4P SRR
Birth weight of first child 2.1 1 0 0.0 0.00 1.0e+00 NT5C2
Peak expiratory flow (PEF) 2.5 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Medication: Paracetamol 3.4 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Headache pain in last month 3.5 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Hypothyroidism/myxoedema (self-reported) 1.5 1 1 3.0 0.00 1.0e+00 U91328.19
Birth weight 3.2 4 2 6.1 -0.55 4.5e-01 CNNM2 CYP17A1-AS1 NT5C2 SRR
High blood pressure (siblings) 2.2 1 0 0.0 0.00 1.0e+00 KAT8
Forced vital capacity (FVC), Best measure 2.5 2 1 3.0 0.00 1.0e+00 KAT8 LRRC37A4P
Body fat percentage 4.7 7 5 15.2 -0.71 7.5e-02 AREL1 INO80E KAT8 MADD RPAIN SRR U91328.19
Leg fat percentage (right) 4.1 6 6 18.2 -0.74 9.2e-02 AREL1 INO80E KAT8 MADD RPAIN U91328.19
Arm fat-free mass (right) 5.1 10 8 24.2 -0.97 3.7e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Comparative body size at age 10 5.4 7 4 12.1 -0.26 5.7e-01 CADM2 KAT8 MADD PACSIN3 SRR U73166.2 U91328.19
Worry too long after embarrassment 6.1 5 1 3.0 1.00 2.8e-04 LRRC37A4P NT5C2 RP11-85F14.5 SRR TP53INP2
Seen a psychiatrist for nerves, anxiety, tension or depression 3.8 1 1 3.0 0.00 1.0e+00 U91328.19
Number of children fathered 2.0 1 0 0.0 0.00 1.0e+00 CADM2
Qualifications: College or University degree 1.9 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Medication for pain relief, constipation, heartburn 3.2 2 1 3.0 0.00 1.0e+00 AREL1 LRRC37A4P
Medication: Ibuprofen 1.8 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Whole body fat mass 5.7 10 6 18.2 -0.80 5.0e-03 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 MADD RPAIN SRR SRSF12 U91328.19
Leg fat mass (right) 5.8 9 6 18.2 -0.95 1.0e-04 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 MADD RPAIN SRSF12 U91328.19
Arm predicted mass (right) 5.1 10 8 24.2 -0.97 4.6e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Alcohol intake frequency. 3.7 5 5 15.2 -0.28 6.5e-01 CADM2 INO80E KAT8 LRRC37A4P MADD
Comparative height size at age 10 1.9 4 3 9.1 -0.66 3.4e-01 CYP17A1-AS1 GNL3 INO80E LRRC37A4P
Suffer from 'nerves' 10.1 7 2 6.1 0.97 2.5e-04 AREL1 CADM2 CYP17A1-AS1 INO80E KAT8 KIAA0825 MADD
Overall health rating 1.9 1 0 0.0 0.00 1.0e+00 KAT8
Supplements: Vitamin C 1.9 1 0 0.0 0.00 1.0e+00 U91328.19
Knee pain experienced in last month 2.2 1 0 0.0 0.00 1.0e+00 TP53INP2
Hypertension (Self-reported) 3.9 4 3 9.1 -0.85 1.5e-01 CNNM2 CYP17A1-AS1 KAT8 MADD
Smoking status: Previous 3.6 1 1 3.0 0.00 1.0e+00 CADM2
Whole body fat-free mass 5.0 10 9 27.3 -0.97 5.3e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Leg fat-free mass (right) 5.3 11 9 27.3 -0.96 2.4e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 PACSIN3 RPAIN SRSF12 TP53INP2 U91328.19
Arm fat percentage (left) 5.1 8 5 15.2 -0.81 1.5e-02 CNNM2 INO80E KAT8 MADD RPAIN SRR SRSF12 U91328.19
Average weekly red wine intake 2.1 1 0 0.0 0.00 1.0e+00 CADM2
Handedness (chirality/laterality): Left-handed 1.7 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Mood swings 6.5 4 3 9.1 0.99 7.0e-03 AREL1 L3MBTL2 LRRC37A4P MADD
Loneliness, isolation 3.8 3 1 3.0 0.00 1.0e+00 LRRC37A4P MADD RP11-85F14.5
Mouth/teeth dental problems: Mouth ulcers 2.4 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Medication for cholesterol 2.8 1 0 0.0 0.00 1.0e+00 KAT8
Smoking status: Current 2.2 1 0 0.0 0.00 1.0e+00 NT5C2
Forced expiratory volume in 1-second (FEV1), predicted percentage 4.4 3 3 9.1 0.00 1.0e+00 KAT8 LRRC37A4P U91328.19
Whole body water mass 5.0 10 9 27.3 -0.97 5.9e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Leg predicted mass (right) 5.3 11 9 27.3 -0.96 2.6e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 PACSIN3 RPAIN SRSF12 TP53INP2 U91328.19
Arm fat mass (left) 6.0 10 6 18.2 -0.82 3.6e-03 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 MADD RPAIN SRR SRSF12 U91328.19
Number of self-reported non-cancer illnesses 2.1 1 0 0.0 0.00 1.0e+00 AREL1
Average weekly champagne plus white wine intake 2.5 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Miserableness 4.6 3 2 6.1 0.00 1.0e+00 LRRC37A4P MADD RP11-85F14.5
Guilty feelings 4.9 3 2 6.1 0.00 1.0e+00 AREL1 LRRC37A4P MADD
Medication: Blood pressure 3.9 4 2 6.1 0.18 8.2e-01 C1GALT1 CNNM2 KAT8 LRRC37A4P
Medication: Bendroflumethiazide 3.0 1 0 0.0 0.00 1.0e+00 KAT8
Medication: Paracetamol 3.3 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Illnesses of father: High blood pressure 2.7 1 0 0.0 0.00 1.0e+00 MADD
Ever smoked 3.8 3 1 3.0 0.00 1.0e+00 CADM2 NT5C2 SRR
Basal metabolic rate 5.3 10 9 27.3 -0.96 7.3e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Leg fat percentage (left) 4.3 6 6 18.2 -0.75 8.3e-02 AREL1 INO80E KAT8 MADD RPAIN U91328.19
Arm fat-free mass (left) 5.1 10 8 24.2 -0.96 7.3e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19
Irritability 4.3 3 2 6.1 0.00 1.0e+00 AREL1 LRRC37A4P TP53INP2
Risk taking 3.9 2 1 3.0 0.00 1.0e+00 CADM2 RP11-85F14.5
Diastolic blood pressure, automated reading 3.5 5 3 9.1 0.51 3.8e-01 CNNM2 CYP17A1-AS1 KAT8 MADD SRR
Vascular/heart problems diagnosed by doctor 3.8 4 3 9.1 0.88 1.2e-01 CNNM2 CYP17A1-AS1 KAT8 MADD
Pain experienced in last month 1.9 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Basal cell carcinoma (self-reported) 2.4 1 1 3.0 0.00 1.0e+00 TP53INP2
Impedance of whole body 4.6 10 8 24.2 0.75 1.3e-02 AREL1 CADM2 CNNM2 CYP17A1-AS1 GNL3 INO80E KAT8 LRRC37A4P TP53INP2 U73166.2
Leg fat mass (left) 6.0 9 6 18.2 -0.94 1.2e-04 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 MADD RPAIN SRSF12 U91328.19
Arm predicted mass (left) 5.2 10 8 24.2 -0.96 7.4e-06 CADM2 CNNM2 CYP17A1-AS1 INO80E KAT8 NT5C2 RPAIN SRSF12 TP53INP2 U91328.19

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 16 0.458 1.85
GTEx Adipose Visceral Omentum 12 0.589 2.04
GTEx Adrenal Gland 9 0.618 1.91
GTEx Artery Aorta 21 0.705 2.03
GTEx Artery Coronary 12 1.014 2.11
GTEx Artery Tibial 18 0.479 1.87
GTEx Brain Caudate basal ganglia 6 0.652 1.96
GTEx Brain Cerebellar Hemisphere 9 0.604 1.96
GTEx Brain Cerebellum 8 0.404 1.95
GTEx Brain Cortex 7 0.676 2.05
GTEx Brain Frontal Cortex BA9 6 0.649 2.18
GTEx Brain Hippocampus 6 1.145 2.16
GTEx Brain Hypothalamus 4 0.678 1.89
GTEx Brain Nucleus accumbens basal ganglia 8 0.925 1.86
GTEx Brain Putamen basal ganglia 4 0.641 1.95
GTEx Breast Mammary Tissue 13 0.659 2.01
GTEx Breast Mammary Tissue (Male) 11 0.922 2.00
GTEx Breast Mammary Tissue (Female) 14 0.852 2.03
GTEx Cells EBV-transformed lymphocytes 13 0.914 2.08
GTEx Cells Transformed fibroblasts 18 0.429 1.87
GTEx Colon Sigmoid 11 0.752 2.03
GTEx Colon Transverse 16 0.775 2.06
GTEx Esophagus Gastroesophageal Junction 11 0.761 2.05
GTEx Esophagus Mucosa 17 0.512 1.88
GTEx Esophagus Muscularis 22 0.681 2.05
GTEx Heart Atrial Appendage 11 0.697 2.02
GTEx Heart Left Ventricle 12 0.784 2.06
GTEx Liver 4 0.558 2.13
GTEx Lung 17 0.592 2.02
GTEx Muscle Skeletal 14 0.484 1.87
GTEx Nerve Tibial 17 0.393 1.88
GTEx Ovary 11 1.211 2.23
GTEx Pancreas 9 0.551 2.01
GTEx Pituitary 11 0.987 2.10
GTEx Prostate 7 0.838 2.06
GTEx Skin Not Sun Exposed Suprapubic 18 0.732 1.97
GTEx Skin Sun Exposed Lower leg 17 0.467 1.89
GTEx Small Intestine Terminal Ileum 9 1.952 2.40
GTEx Spleen 9 0.638 2.10
GTEx Stomach 11 0.757 2.02
GTEx Testis 19 0.602 1.93
GTEx Thyroid 20 0.500 1.95
GTEx Uterus 8 1.411 2.21
GTEx Vagina 10 1.575 2.18
GTEx Whole Blood 9 0.452 1.87
METSIM Adipose 6 0.130 1.66
NTR Blood 7 0.291 1.80
ROSMAP Brain Pre-frontal Cortex 31 0.706 2.02
YFS Blood 5 0.108 1.65
CommonMind Brain Pre-frontal Cortex 11 0.205 1.76
TCGA Breast Tumor 3 0.391 1.84
TCGA Breast Normal 6 0.143 1.62
TCGA Ovarian Tumor 14 0.479 1.71
TCGA Prostate Tumor 9 0.260 1.75