TWAS hub - KIAA0825

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1010	0.0280	1.3e-06	0.068	0.027	0.047	0.045	0.058	1.0e-08	0.00024	2.0e-06	3.1e-06	1.4e-07
2	GTEx	Adipose Subcutaneous	0.1280	0.0400	2.6e-05	0.057	NA	0.069	NA	0.067	2.0e-05	NA	2.5e-06	NA	3.4e-06
3	GTEx	Whole Blood	0.1070	0.0350	3.2e-05	0.093	NA	0.075	NA	0.027	7.2e-09	NA	2.0e-07	NA	1.5e-03
4	METSIM	Adipose	0.0241	0.0125	1.7e-02	0.009	0.006	-0.001	0.006	0.001	1.5e-02	0.04000	4.2e-01	3.7e-02	2.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Hearing difficulty/problems with background noise	6.2	9.9	22.5	2.4	2.4	4.7	2.4
Nervous feelings	5.8	10.9	35.6	0.7	1.2	6.0	2.5
Mouth/teeth dental problems	5.1	7.8	11.3	-2.6	-2.3	-3.4	-2.8
Mean time to correctly identify matches	4.8	9.2	20.6	2.2	2.7	1.9	4.5
Qualifications: A levels/AS levels or equivalent	4.7	10.5	15.0	-3.7	-3.9	-2.8	-2.4
Reaction Time	4.3	8.2	14.0	2.7	3.1	1.3	3.7
Worry too long after embarrassment	4.2	7.0	14.5	2.2	1.5	3.8	2.6
Suffer from ‘nerves’	3.9	6.2	18.8	1.4	1.4	4.3	1.4
Hand grip strength (left)	3.8	10.1	20.3	-2.4	-2.9	-2.4	-4.5
Bipolar Disorder (2018)	3.5	5.6	10.2	-1.4	-0.8	-3.1	-3.2
Type 2 Diabetes (T2D) (2012)	3.5	4.1	7.5	2.7	2.0	0.9	2.0
Mouth/teeth dental problems: Dentures	3.4	5.7	9.4	2.5	3.1	2.2	1.5
Bipolar Disorder (2011)	3.3	3.2	5.6	-1.0	-1.0	-2.4	-2.3
Hearing difficulty/problems: Yes	3.3	5.0	18.0	0.9	1.0	4.2	0.5
Frequency of tenseness / restlessness in last 2 weeks	3.3	5.1	7.8	2.5	2.8	2.2	1.4
Blood clot in the leg (DVT)	3.3	4.2	7.6	2.8	2.0	1.5	1.8
Hand grip strength (right)	3.1	8.5	17.2	-2.4	-2.9	-1.6	-4.1
Medication: Simvastatin	3.1	4.5	7.9	1.3	1.0	2.8	2.8
Mouth/teeth dental problems: Bleeding gums	3.0	3.9	7.5	1.6	0.6	2.7	2.3
Commuting to job workplace: Car/motor vehicle	3.0	3.5	5.9	-1.6	-1.7	-1.6	-2.4
Back pain experienced in last month	3.0	4.3	7.7	-2.8	-2.4	-0.3	-2.0
Serious illness, injury or assault to yourself	2.9	3.5	7.5	-2.2	-2.7	0.4	-1.2
Smoking Status	2.8	6.8	15.8	-1.3	-1.5	-2.8	-4.0
Eye problems/disorders: Diabetes related eye disease	2.8	3.1	6.0	0.9	1.3	2.5	1.9
Number of full sisters	2.7	3.3	5.0	-2.1	-2.2	-1.1	-1.6
Breast cancer (self-reported)	2.7	3.2	4.4	-0.9	-2.1	-2.1	-1.7
Illnesses of father: High blood pressure	2.6	3.2	6.6	-2.0	-1.2	-0.9	-2.6
Deep venous thrombosis (DVT) (self-reported)	2.5	3.2	6.3	2.5	1.6	1.2	1.6
Average weekly spirits intake	2.4	2.9	7.5	0.1	-0.5	-2.7	-2.0
Number of live births	2.4	3.4	7.9	-0.3	-0.5	-2.8	-2.3
Sensitivity / hurt feelings	2.3	4.0	10.5	1.3	1.7	3.2	0.9
Frequency of tiredness / lethargy in last 2 weeks	2.3	3.7	10.5	1.4	1.0	3.2	1.2
Breastfed as a baby	2.2	2.7	4.3	-1.0	-1.3	-1.9	-2.1
Current tobacco smoking	2.1	3.4	6.0	-2.0	-1.8	-0.5	-2.4
Medication: Cholesterol lowering	2.1	3.3	9.4	0.6	0.3	3.1	1.8
Father’s age at death	2.0	2.7	3.3	-1.6	-1.3	-1.8	-1.8
Bipolar Disorder or Schizophrenia	1.9	4.7	11.4	-0.9	-0.8	-2.4	-3.4
Worry (Nagel 2018)	1.9	4.0	12.1	1.3	1.1	3.5	1.0
Medication: Lansoprazole	1.9	2.2	4.3	0.6	0.8	2.1	1.9
Smoking status: Previous	1.9	2.8	8.5	0.6	0.1	-2.9	-1.6
Medication for hormone replacement therapy	1.8	2.0	3.6	-1.0	-0.9	-1.6	-1.9
Number of incorrect matches in round	1.8	2.9	7.1	1.5	1.4	-0.7	2.7
Past tobacco smoking	1.8	3.2	7.3	-0.4	-0.2	2.7	2.3
Hair/balding pattern: Pattern 2	1.8	2.3	4.7	-0.3	0.4	-2.2	-2.0
Pulse wave Arterial Stiffness index	1.8	2.2	3.1	1.8	1.7	0.5	1.5
Length of working week for main job	1.8	2.0	4.3	0.9	0.2	-2.1	-1.6
Tense / ‘highly strung’	1.8	3.0	6.8	1.6	1.4	2.6	0.7
Smoking status: Current	1.8	2.9	5.6	-1.7	-1.7	-0.5	-2.4
Number of operations (self-reported)	1.8	2.7	6.2	-1.4	-1.4	-0.9	-2.5
Frequency of depressed mood in last 2 weeks	1.7	2.4	3.8	1.7	1.3	2.0	1.1
Qualifications: O levels/GCSEs or equivalent	1.7	2.6	5.5	-2.3	-1.9	-0.5	-1.2
Diabetes (mother)	1.6	2.1	3.8	-2.0	-1.4	-0.9	-1.4
Falls in the last year	1.6	2.1	6.5	0.8	1.1	2.5	-0.2
Noisy workplace	1.6	1.9	3.5	1.8	1.9	0.4	0.8
Bilateral oophorectomy (both ovaries removed)	1.5	1.8	3.0	1.4	1.7	1.4	0.5
Peak expiratory flow (PEF)	1.5	3.5	12.1	-0.4	-1.2	-0.4	-3.5
Overall health rating	1.5	3.3	12.4	-0.1	-0.5	3.5	0.7
Loneliness, isolation	1.5	2.0	4.8	2.2	1.7	0.5	0.5
Illnesses of father: None of the above (group 1)	1.5	1.8	3.3	1.8	1.2	0.5	1.5
Tinnitus: Yes, now most or all of the time	1.5	1.7	3.0	-1.7	-1.7	-0.5	-0.9
Ever smoked	1.5	2.6	7.8	0.5	-0.1	-1.6	-2.8
Pain experienced in last month	1.5	2.5	4.7	1.7	1.4	0.7	2.2
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	3.5	0.7	-0.4	-1.9	-1.6
Chronic bronchitis/emphysema (mother)	1.4	1.6	3.2	1.6	1.8	-0.1	0.7
Pulse wave peak to peak time	1.4	1.6	2.2	-1.4	-1.4	-0.6	-1.5
Qualifications: College or University degree	1.4	4.5	10.4	-1.3	-2.2	-3.2	-0.9
Knee pain experienced in last month	1.4	2.1	4.6	-2.1	-1.6	0.8	-0.8
Average weekly red wine intake	1.4	2.0	2.6	-1.2	-1.3	1.6	1.6
Average weekly champagne plus white wine intake	1.4	2.0	3.3	1.8	1.7	1.0	0.8
Mean Putamen Volume	1.3	1.5	3.3	0.4	0.9	1.4	1.8
Neuroticism (2016)	1.3	1.9	4.5	0.7	1.5	2.1	0.4
Average weekly fortified wine intake	1.3	1.5	4.6	0.9	0.2	2.1	0.8
Coronary Artery Disease (CAD)	1.2	1.4	2.4	1.5	1.2	0.9	1.1
LDL Cholesterol	1.2	2.0	3.9	2.0	1.4	0.8	1.2
Chronotype (morning person)	1.2	2.7	5.4	1.5	1.7	-2.3	-0.3
Shortness of breath walking on level ground	1.2	1.4	4.2	0.7	0.5	2.1	0.9
Qualifications: nursing, teaching	1.2	1.9	3.9	-1.5	-0.6	-2.0	-1.1
Guilty feelings	1.2	1.9	3.8	1.9	1.8	-0.1	0.5
Age started oral contraceptive pill	1.2	1.5	4.4	0.7	0.8	0.6	2.1
Crohns Disease (2012)	1.1	1.7	4.7	-2.2	-1.3	-0.3	-0.6
Angina	1.1	1.5	2.7	-0.9	-1.3	0.8	-1.6
Diabetes (father)	1.1	1.4	2.8	-0.2	-0.3	-1.6	-1.7
Hair/balding pattern: Pattern 3	1.1	1.7	3.5	-1.2	-0.9	1.9	0.9
Happiness	1.1	1.3	3.8	-0.6	-1.0	-0.1	-1.9
Ever highly irritable/argumentative for 2 days	1.1	1.3	2.7	1.6	1.5	-0.3	0.0
Migraine (self-reported)	1.1	1.4	1.9	-1.2	-1.4	-0.9	-1.2
Irritability	1.1	1.8	3.8	-0.8	-0.2	-1.7	-2.0
Risk taking	1.1	1.6	5.2	-0.2	-0.3	-2.3	-1.1
Prostate Cancer	1.0	1.4	2.2	-1.3	-1.5	-1.2	-0.6
Body Mass Index (BMI) (2010)	1.0	1.4	3.2	-0.0	-0.4	-1.5	-1.8
Number of treatments/medications taken	1.0	1.8	4.6	-1.0	-1.1	2.2	0.7
Supplements: Zinc	1.0	1.1	1.9	0.9	0.8	-0.9	-1.4
Maternal smoking around birth	1.0	1.4	4.8	0.4	0.6	-2.2	-0.7
Alcohol usually taken with meals	1.0	1.6	2.9	-1.7	-1.4	1.2	0.4
Pain all over the body in last month	1.0	1.1	2.6	0.9	0.0	1.6	1.0
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	3.9	0.4	0.3	-2.0	-1.5
Medication: Amlodipine	1.0	1.4	3.0	-0.4	-0.7	1.7	1.5
Comparative body size at age 10	1.0	2.9	5.2	-1.6	-2.3	-1.7	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	3.8	-0.1	-0.4	-1.0	-1.9
Health satisfaction	1.0	1.3	3.1	1.1	0.2	1.8	1.0
Angina (self-reported)	1.0	1.3	2.2	-0.8	-1.2	0.9	-1.5
Mouth/teeth dental problems: Mouth ulcers	1.0	1.7	3.0	1.7	1.6	0.4	0.9
Mother’s age at death	1.0	1.3	1.6	-1.0	-1.3	-1.3	-0.9
Medication: Blood pressure	1.0	1.8	4.2	-0.5	-0.4	2.0	1.6
Intelligence (Savage-Jansen 2018)	0.9	2.7	5.1	-2.2	-2.3	-0.9	-0.4
Schizophrenia vs Biploar Disorder	0.9	1.2	2.6	0.9	1.0	1.6	0.7
Taking other prescription medications	0.9	1.4	2.9	1.1	0.6	1.7	1.1
Qualifications: CSEs or equivalent	0.9	1.2	3.5	0.6	1.0	1.9	0.3
Medication: Levothyroxine sodium	0.9	1.5	2.9	0.4	-0.3	1.7	1.7
Neuroticism score	0.9	1.9	4.5	1.0	1.3	2.1	0.5
Medication: Bendroflumethiazide	0.9	1.4	4.5	0.3	0.3	1.0	2.1
Neuroticism (Nagel 2018)	0.8	1.8	2.8	1.5	1.4	1.7	-0.2
Major Depression (MDD)	0.8	1.0	1.7	0.9	1.3	0.3	-1.2
HbA1C	0.8	0.9	2.4	0.5	0.3	1.5	-0.9
Schizophrenia (2014)	0.8	1.7	5.0	-0.3	-0.3	-1.2	-2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.7	0.5	0.9	1.6	0.8
High blood pressure (mother)	0.8	1.2	3.5	0.7	0.6	1.9	0.6
Had menopause	0.8	0.9	3.2	-0.1	0.6	0.4	1.8
Financial difficulties in last 2 years	0.8	1.1	2.5	1.3	0.2	1.6	-0.4
Alcohol intake versus 10 years previously	0.8	1.1	2.6	-0.9	-0.2	-1.6	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.4	0.9	0.5	1.5	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	4.5	0.1	-0.6	-0.4	-2.1
Pulse wave reflection index	0.8	1.0	1.6	0.9	1.3	0.9	1.0
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.2	-1.2	-1.5	-0.1	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	1.6	1.2	1.3	0.9	-0.3
Illnesses of father: Heart disease	0.8	1.1	2.2	-1.5	-1.4	-0.4	-0.2
Fractured/broken bones in last 5 years	0.8	1.1	2.8	1.7	0.7	0.9	0.3
Fasting Glucose	0.7	0.8	1.1	-1.0	-0.9	1.1	-0.6
Primary Biliary Cirrhosis	0.7	1.0	2.0	0.9	0.4	1.4	0.9
Pack years adult smoking proportion	0.7	1.1	2.0	-0.9	-0.9	-0.9	-1.4
High blood pressure	0.7	2.0	4.5	-0.2	-1.0	2.1	1.5
Stomach or abdominal pain in last month	0.7	0.8	2.7	-0.5	-0.6	0.1	-1.6
Qualifications: None of the above	0.7	1.4	2.3	1.1	1.3	1.5	0.7
Allergy	0.7	1.5	4.8	-1.1	0.0	-2.2	-0.1
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.9	0.4	0.1	1.7	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	1.2	1.1	0.8	-0.9	0.8
Had major operations	0.7	0.8	2.8	0.3	0.1	-0.6	-1.7
Family relationship satisfaction	0.7	0.9	2.1	-0.8	-0.9	-0.1	-1.4
Hypertension (Self-reported)	0.7	2.1	3.8	-1.0	-1.5	2.0	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	3.4	1.8	1.6	0.1	-0.3
Miserableness	0.7	1.2	3.3	0.3	0.2	-1.2	-1.8
Financial situation satisfaction	0.7	0.9	1.8	0.2	-1.0	1.3	-0.9
Medication: Lisinopril	0.7	1.0	1.7	-1.3	-1.2	-0.9	0.1
Medication: Atorvastatin	0.7	0.8	2.6	-0.7	-0.3	-0.1	-1.6
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.6	1.2	0.8	1.1	0.1
Vascular/heart problems diagnosed by doctor	0.7	2.0	4.2	0.5	1.3	-2.0	-1.3
Depressed Affect (Nagel 2018)	0.6	1.2	2.5	1.0	0.7	-1.0	-1.6
Depression (Nagel 2018)	0.6	0.9	3.5	0.1	0.2	1.9	0.4
Alzheimer’s Disease (in mother)	0.6	0.7	1.3	1.2	0.6	-0.1	1.1
Ulcerative Colitis (UC)	0.6	1.1	2.4	-0.7	-0.9	-1.6	-0.9
Breast Cancer	0.6	1.3	2.1	-1.4	-1.1	1.4	0.2
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.2	0.7	0.4	-1.5	-0.7
Fed-up feelings	0.6	1.0	2.1	1.4	1.3	-0.2	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	4.1	-1.1	-0.4	-2.0	-0.4
Medication: Atenolol	0.6	0.8	2.7	-0.4	-0.3	1.6	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	4.7	-0.3	0.1	-2.2	-0.6
Heart attack	0.6	0.7	1.2	1.1	0.9	0.9	-0.1
Medication: Ramipril	0.6	0.8	1.1	-1.0	-1.0	1.0	-0.1
Asthma	0.6	1.2	2.7	1.4	0.3	1.6	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.3	0.1	-0.7	-0.6	-1.5
Gout (self-reported)	0.6	0.8	2.5	0.5	0.6	-1.6	0.2
Medication: Allopurinol	0.6	0.8	2.4	-0.2	-0.6	-1.5	-0.7
Medication: Seretide 50 evohaler	0.6	0.7	1.3	1.1	1.2	0.1	0.6
Heart disease (mother)	0.6	0.7	1.6	0.7	0.9	1.3	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.8	2.1	0.5	1.5	0.3	0.7
Number of self-reported non-cancer illnesses	0.6	1.1	3.8	-0.2	-0.2	1.9	0.7
Ever taken oral contraceptive pill	0.6	0.6	1.9	-0.5	-0.5	-0.3	-1.4
Unable to work because of sickness or disability	0.6	0.7	1.1	-1.0	-0.9	1.1	0.2
Myopia	0.6	0.9	2.4	0.4	1.0	1.5	-0.0
Pack years of smoking	0.6	0.9	1.5	-0.9	-0.8	-0.8	-1.2
Alzheimer’s Disease (including proxy)	0.5	0.8	1.3	1.0	0.5	1.1	0.7
Verbal and Numeric Reasoning (VNR)	0.5	1.2	2.6	-1.5	-1.6	-0.4	0.2
Ulcerative Colitis	0.5	0.7	1.4	-0.7	-0.6	-1.2	-0.8
Waist Hip Ratio (WHR)	0.5	2.1	4.4	-1.5	-2.1	-0.9	-1.0
Hypothyroidism (self reported)	0.5	1.0	2.9	-0.8	-1.7	-0.5	-0.6
Type 2 Diabetes (T2D) (2018)	0.5	0.9	1.3	-1.2	-1.0	-0.6	-0.8
Waist circumference	0.5	1.9	4.2	-1.7	-2.1	0.5	0.1
Prospective memory result	0.5	0.7	2.3	0.4	0.4	-0.3	1.5
Impedance of arm (left)	0.5	2.3	3.2	1.8	1.6	1.4	1.2
Exposure to tobacco smoke at home	0.5	0.5	1.4	1.2	0.7	0.4	0.2
Neck or shoulder pain in last month	0.5	0.7	2.1	-0.3	-0.1	-0.8	-1.5
Medication: Blood pressure	0.5	0.9	1.2	-1.0	-0.8	1.0	1.1
Chest pain or discomfort	0.5	0.8	1.8	1.0	0.4	-0.2	-1.4
Medication: Aspirin	0.5	0.6	1.7	0.1	0.6	0.6	1.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.4	0.5	0.8	-0.1	1.2
High cholesterol (Self-reported)	0.5	0.9	2.0	0.6	1.1	1.4	0.2
Alcohol drinker status: Never	0.5	0.6	1.7	0.5	0.7	0.1	1.3
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.2	0.9	0.6	1.1	-0.1
Schizophrenia (2018)	0.4	0.9	3.1	-0.1	-0.4	-0.6	-1.8
Alzheimer’s Disease (in father)	0.4	0.5	1.7	0.3	-0.1	1.3	-0.4
Lupus	0.4	0.6	1.9	0.3	-0.1	1.4	0.7
Triglycerides	0.4	0.7	1.2	1.1	0.7	0.9	0.6
Lung FEV1/FVC ratio	0.4	2.2	5.8	-0.7	-1.3	2.4	0.9
Neuroticism	0.4	1.0	2.8	0.8	0.8	1.7	-0.3
Tanning	0.4	5.0	10.5	0.1	-0.0	-3.2	-3.1
Ever had hysterectomy (womb removed)	0.4	0.4	1.2	0.4	-0.4	1.1	-0.1
Systolic blood pressure, automated reading	0.4	1.3	3.4	0.5	0.1	1.2	1.8
Impedance of leg (right)	0.4	2.0	3.6	1.9	1.4	-1.1	-1.1
Age when periods started (menarche)	0.4	0.9	2.8	-0.3	0.3	1.7	-0.8
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.8	-0.5	-1.3	0.8	-0.7
Impedance of leg (left)	0.4	2.0	3.6	1.9	1.4	-1.4	-0.9
Impedance of arm (right)	0.4	1.8	3.2	1.8	1.7	0.7	0.7
Illnesses of mother	0.4	0.4	1.7	0.0	0.0	-1.3	0.2
Headache pain in last month	0.4	0.7	1.7	0.3	1.3	0.5	-0.9
High blood pressure (siblings)	0.4	0.6	1.1	-0.9	-0.5	0.2	-1.0
Exposure to tobacco smoke outside home	0.4	0.6	1.3	0.7	0.7	0.2	1.1
Number of full brothers	0.4	0.5	1.0	0.5	0.5	-0.7	-1.0
Eye problems/disorders: None of the above	0.4	0.5	1.6	-0.3	-0.4	-0.5	-1.3
Supplements: Vitamin C	0.4	0.5	0.6	0.7	0.7	0.8	0.7
Arm fat percentage (left)	0.4	1.7	2.5	-0.8	-1.2	1.5	1.6
Ever had bowel cancer screening	0.4	0.5	0.9	-0.5	-1.0	0.7	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.0	1.0	0.5	-0.7	-0.3
Eye problems/disorders: Cataract	0.4	0.5	1.4	-0.0	0.8	0.2	1.2
Medication for cholesterol	0.4	0.7	2.1	0.3	0.0	-1.4	-0.7
Asthma (self-reported)	0.4	0.8	1.8	1.3	0.3	1.1	-0.1
Osteoporosis (self-reported)	0.4	0.5	0.7	0.4	0.8	0.6	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	1.5	-1.2	-1.1	0.4	-0.1
Hearing aid user	0.4	0.5	1.1	-0.3	-0.6	1.0	0.7
Arm fat-free mass (left)	0.4	2.0	3.5	-1.5	-1.9	-0.8	-1.2
Ever depressed for a whole week	0.4	0.5	1.5	-0.2	-0.7	0.2	-1.2
Heart disease (siblings)	0.4	0.5	1.3	0.5	0.4	-1.1	-0.4
Irritable Bowel Disease (IBD)	0.3	0.7	1.4	-0.4	-0.2	-1.2	-1.1
Ovarian Cancer	0.3	0.4	1.3	0.3	0.2	1.1	0.2
Rheumatoid Arthritis	0.3	0.4	0.5	0.6	0.5	0.7	0.7
BMI	0.3	1.5	3.4	-1.2	-1.9	0.3	1.0
Allergy or Eczema	0.3	0.9	1.4	-0.7	-1.1	1.2	-0.8
Cardiovascular Disease	0.3	1.0	1.9	-0.5	-1.3	1.4	0.6
Lung FVC	0.3	1.8	3.1	1.0	1.7	-1.8	-0.1
Relative age of first facial hair	0.3	0.6	2.1	0.0	-0.2	-0.5	-1.4
Medication: Co-codamol	0.3	0.4	0.6	0.7	0.3	0.8	0.5
Chronic bronchitis/emphysema (father)	0.3	0.4	1.1	-0.0	-0.0	-1.0	-0.7
Body mass index (BMI)	0.3	1.3	2.5	-1.3	-1.6	0.6	0.9
Had other major operations	0.3	0.4	1.2	-0.3	-0.3	-0.5	-1.1
Illnesses of siblings	0.3	0.4	0.7	0.7	0.3	0.5	0.8
Weight	0.3	1.3	3.0	-1.4	-1.7	0.4	-0.1
Arm fat percentage (right)	0.3	1.4	2.2	-0.7	-1.0	1.3	1.5
Trunk fat-free mass	0.3	1.4	2.1	-1.2	-1.5	-0.7	-1.3
Lung cancer (father)	0.3	0.3	0.7	-0.3	-0.8	0.5	-0.4
Arm fat mass (right)	0.3	1.2	2.5	-1.1	-1.6	0.6	0.8
Birth weight of first child	0.3	0.5	1.3	0.8	0.4	0.1	1.2
Loud music exposure frequency	0.3	0.4	1.0	1.0	0.5	0.2	0.3
Arm fat-free mass (right)	0.3	1.7	2.7	-1.2	-1.6	-0.9	-1.3
Emphysema/chronic bronchitis	0.3	0.3	0.7	0.9	0.7	0.4	-0.0
Medication: Ibuprofen	0.3	0.4	1.3	0.1	-0.4	0.2	-1.1
Leg fat mass (right)	0.3	1.2	3.1	-1.4	-1.8	0.0	-0.0
Arm predicted mass (right)	0.3	1.5	2.9	-1.0	-1.7	-0.7	-1.3
Whole body fat-free mass	0.3	1.6	3.0	-1.4	-1.7	-0.4	-1.1
Leg fat-free mass (right)	0.3	1.3	2.8	-1.5	-1.7	0.1	-0.5
Long-standing illness, disability or infirmity	0.3	0.4	1.1	-0.3	-0.7	1.0	-0.3
Commuting to job workplace: Walk	0.3	0.3	0.6	-0.3	-0.6	-0.6	-0.7
Whole body water mass	0.3	1.7	3.0	-1.5	-1.7	-0.6	-1.2
Arm fat mass (left)	0.3	1.2	2.1	-0.9	-1.4	0.9	1.0
Wears glasses or contact lenses	0.3	0.4	0.6	0.8	0.7	-0.3	-0.6
Commuting to job workplace: Public transport	0.3	0.4	1.1	-1.1	-0.3	-0.5	-0.0
Medication: Paracetamol	0.3	0.5	0.7	-0.8	-0.0	0.8	0.8
Cholesterol lowering medication	0.3	0.5	0.7	0.7	0.5	0.8	0.8
Supplements: Calcium	0.3	0.4	0.6	-0.3	-0.7	-0.8	0.6
Impedance of whole body	0.3	1.7	4.0	2.0	1.6	-0.1	0.0
Arm predicted mass (left)	0.3	1.5	2.0	-1.2	-1.4	-0.9	-1.3
Heel T-Score	0.2	1.2	2.7	0.3	0.5	-1.6	-1.3
Systolic Blood Pressure	0.2	1.0	2.1	0.3	-0.5	1.4	1.3
Respiratory disease	0.2	0.4	1.0	0.7	-0.1	1.0	0.1
Severe depression (siblings)	0.2	0.2	0.4	0.0	0.5	0.6	0.1
Leg fat-free mass (left)	0.2	1.2	2.6	-1.4	-1.6	0.3	-0.5
Trunk fat percentage	0.2	0.7	0.9	-0.5	-1.0	0.8	0.9
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.5	0.6	0.4	-0.7	-0.0
Sitting height	0.2	1.3	4.8	-0.4	0.1	-0.1	-2.2
Leg predicted mass (left)	0.2	1.3	2.7	-1.4	-1.6	0.2	-0.6
Trunk fat mass	0.2	0.8	1.8	-0.9	-1.4	0.5	0.3
Forced vital capacity (FVC)	0.2	0.7	2.2	-0.1	-0.1	-0.8	-1.5
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.8	-0.2	-0.9	-0.4	-0.2
Diabetes (self-reported)	0.2	0.3	0.6	0.3	0.3	0.8	0.7
Hip circumference	0.2	0.7	1.0	-0.7	-0.9	1.0	0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.9	0.1	0.0	-0.4	-1.7
Pulse rate	0.2	0.3	0.9	0.2	-0.4	1.0	0.1
Trunk predicted mass	0.2	1.2	1.8	-1.1	-1.3	-0.7	-1.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.9	0.2	-0.4	0.5	0.9
Body fat percentage	0.2	0.6	1.0	-0.6	-1.0	0.7	0.9
Leg fat percentage (right)	0.2	0.9	2.1	-1.2	-1.4	0.1	0.2
Medication for pain relief, constipation, heartburn	0.2	0.3	0.9	1.0	-0.0	-0.3	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	-0.4	-0.4	0.6	-0.4
Whole body fat mass	0.2	1.0	1.8	-0.9	-1.4	0.8	0.7
Pulse rate, automated reading	0.2	0.6	1.2	-0.5	0.0	1.1	1.0
Alcohol intake frequency.	0.2	0.5	0.8	0.9	0.6	0.8	0.5
Leg pain on walking	0.2	0.2	0.7	0.3	0.1	-0.9	-0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.4	-0.3	0.5	-0.6	0.6
Mood swings	0.2	0.4	1.1	0.4	0.3	-0.4	-1.1
Diabetes diagnosed by doctor	0.2	0.4	0.9	0.4	0.4	0.7	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	-0.4	-0.2	0.8	-0.0
Mineral and other dietary supplements	0.2	0.3	0.5	-0.3	-0.4	0.5	-0.7
Osteoarthritis (self-reported)	0.2	0.3	0.7	0.4	0.9	0.3	0.3
Medication: Aspirin	0.2	0.3	1.0	0.1	0.4	0.3	1.0
Medication: Gliclazide	0.2	0.3	0.5	-0.7	0.7	-0.1	-0.2
Leg predicted mass (right)	0.2	1.3	2.7	-1.5	-1.6	0.1	-0.5
Eye problems/disorders: Glaucoma	0.2	0.3	0.6	0.2	-0.4	0.8	0.5
Basal metabolic rate	0.2	1.4	2.9	-1.4	-1.7	-0.1	-0.8
Leg fat percentage (left)	0.2	0.8	1.7	-1.1	-1.3	-0.1	0.4
Commuting to job workplace: Cycle	0.2	0.2	0.8	-0.2	-0.2	-0.2	0.9
Basal cell carcinoma (self-reported)	0.2	0.2	0.5	-0.2	0.0	0.7	-0.6
Alcohol drinker status: Previous	0.2	0.2	0.4	-0.5	-0.5	-0.1	-0.6
Leg fat mass (left)	0.2	1.0	2.3	-1.2	-1.5	0.0	0.2
Crohns Disease (2017)	0.1	0.1	0.3	-0.3	0.1	-0.3	-0.6
Age at First Birth	0.1	0.2	0.5	0.7	0.4	0.1	0.1
HDL Cholesterol	0.1	0.2	0.3	-0.3	-0.5	0.5	0.2
Blood Platelet Count	0.1	1.1	2.8	-1.7	-1.2	-0.1	-0.5
Blood White Count	0.1	0.7	1.2	-1.0	-0.6	1.1	-0.4
Height	0.1	1.6	2.8	-1.4	-1.2	-0.2	-1.7
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.4	0.1	-0.2	-0.7	-0.4
Vitamin and mineral supplements	0.1	0.1	0.1	-0.3	-0.2	0.0	0.4
Medication: Metformin	0.1	0.1	0.3	-0.1	0.3	0.1	0.6
Townsend deprivation index at recruitment	0.1	0.2	0.6	-0.2	0.3	-0.7	-0.3
Relative age voice broke	0.1	0.2	0.7	-0.1	0.0	0.2	-0.8
Multivitamins +/- minerals	0.1	0.2	0.4	0.6	0.4	0.1	-0.2
Supplements: Glucosamine	0.1	0.2	0.3	-0.4	-0.6	-0.4	-0.3
Fluid intelligence score	0.1	0.2	0.4	-0.4	-0.6	-0.3	0.0
Worrier / anxious feelings	0.1	0.3	0.4	-0.6	-0.2	0.7	0.6
Depression (self-reported)	0.1	0.1	0.2	-0.2	-0.4	-0.3	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.7	0.6	0.7	0.1	-0.8
Standing height	0.1	0.7	2.6	0.0	-0.3	-0.3	-1.6
Medication: Paracetamol	0.1	0.2	0.3	-0.6	0.2	0.3	0.5
Glaucoma (self-reported)	0.1	0.1	0.4	0.1	-0.2	0.6	0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.6	0.1	-0.2	-0.2	-0.7
Forced vital capacity (FVC), Best measure	0.1	0.4	1.0	0.2	0.4	-0.5	-1.0
Wheeze or whistling in the chest in last year	0.1	0.2	0.6	0.4	-0.0	0.7	-0.2
Number of children fathered	0.1	0.1	0.1	0.1	-0.4	0.0	-0.3
Age at first live birth	0.1	0.2	0.5	-0.6	-0.7	0.2	0.0
Age at last live birth	0.1	0.1	0.2	-0.2	-0.4	0.4	0.0
Illnesses of siblings: Diabetes	0.1	0.1	0.5	0.0	0.7	0.1	0.3
Friendships satisfaction	0.1	0.2	0.4	-0.7	-0.4	0.2	-0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.3	0.4	-0.1	-0.3	-0.6
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.4	-0.3	0.2	-0.6	0.4
Average weekly beer plus cider intake	0.1	0.2	0.4	-0.0	0.4	-0.7	0.2
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	-0.5	0.2	0.2	-0.2
Blood Eosinophil Count	0.0	0.1	0.1	-0.0	0.3	0.4	-0.1
Blood Red Count	0.0	0.4	1.1	0.2	0.3	1.1	0.4
Hair Pigment	0.0	0.8	2.0	-1.4	-1.1	0.2	-0.1
Time employed in main current job	0.0	0.0	0.1	-0.2	-0.2	0.1	-0.3
Hair/balding pattern: Pattern 4	0.0	0.1	0.3	0.4	-0.1	0.6	0.1
Birth weight	0.0	0.1	0.2	-0.1	0.3	-0.2	-0.5
Medication: Omeprazole	0.0	0.0	0.1	-0.2	0.0	0.2	-0.0
Comparative height size at age 10	0.0	0.2	0.4	-0.0	-0.6	-0.2	0.6
Diastolic blood pressure, automated reading	0.0	0.2	0.4	0.6	0.0	0.1	0.5

Hub : Genes

KIAA0825

Models

Trait associations