TWAS hub - SRSF12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2010	0.0410	3.8e-13	0.118	0.133	0.139	0.143	0.136	3.6e-14	6.2e-16	1.5e-16	5.1e-17	3.0e-16
2	GTEx	Artery Aorta	0.1190	0.0440	4.5e-04	0.022	NA	0.003	NA	0.025	2.1e-02	NA	2.1e-01	NA	1.5e-02
3	GTEx	Artery Tibial	0.1155	0.0484	6.5e-03	0.059	NA	0.060	NA	0.039	2.1e-05	NA	1.7e-05	NA	4.5e-04
4	GTEx	Cells Transformed fibroblasts	0.1130	0.0320	3.3e-06	0.162	NA	0.156	NA	0.158	3.4e-12	NA	9.3e-12	NA	6.1e-12
5	GTEx	Esophagus Mucosa	0.1280	0.0540	8.0e-03	0.066	NA	0.042	NA	0.082	3.3e-05	NA	8.3e-04	NA	3.9e-06
6	GTEx	Esophagus Muscularis	0.0670	0.0300	7.1e-03	0.032	NA	0.029	NA	0.034	4.5e-03	NA	7.2e-03	NA	3.9e-03
7	GTEx	Skin Not Sun Exposed Suprapubic	0.1860	0.0610	1.7e-04	0.022	NA	0.053	NA	0.058	2.1e-02	NA	7.0e-04	NA	4.3e-04
8	ROSMAP	Brain Pre-frontal Cortex	0.0971	0.0256	1.1e-08	0.083	0.071	0.084	0.076	0.083	8.5e-11	1.7e-09	6.2e-11	4.9e-10	8.9e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Alcohol intake versus 10 years previously	9.7	14.5	26.3	-4.5	-5.1	-3.7	-4.7	-0.7	-2.0	-3.4	-4.3
Ever had stillbirth, spontaneous miscarriage or termination	3.6	3.8	10.0	-3.2	-1.8	-1.0	-2.1	-1.1	0.8	-2.5	-1.8
Nervous feelings	3.5	6.6	26.9	2.9	1.5	-0.1	2.2	1.5	1.9	5.2	2.1
Hearing difficulty/problems: Yes	3.2	4.8	8.2	1.0	2.3	0.9	2.8	1.7	2.9	2.5	2.4
Hearing difficulty/problems with background noise	3.2	5.2	11.8	1.1	2.0	1.2	2.4	1.4	3.3	3.4	2.0
Average weekly beer plus cider intake	3.2	4.6	10.6	-1.2	-0.5	-2.2	-2.5	-2.0	-3.2	-2.5	-2.0
Worry too long after embarrassment	2.9	4.8	10.6	3.0	2.2	1.4	2.3	1.1	0.5	3.3	2.3
Handedness (chirality/laterality): Left-handed	2.9	3.4	8.6	1.5	2.9	1.5	2.1	0.4	1.5	1.0	2.6
Ever depressed for a whole week	2.6	3.3	6.5	2.3	2.1	1.0	2.6	-0.2	1.5	1.4	2.1
Schizophrenia vs Biploar Disorder	2.5	3.3	8.5	2.5	2.9	1.3	2.2	0.3	-1.6	0.3	1.7
Neuroticism	2.5	6.1	20.8	2.7	1.3	-0.6	2.3	1.7	2.0	4.6	2.4
Health satisfaction	2.5	3.2	6.0	2.1	1.9	0.2	2.4	1.3	-0.0	2.4	2.1
Guilty feelings	2.5	3.7	7.7	2.4	1.3	0.3	2.6	1.3	1.2	2.8	2.2
Qualifications: None of the above	2.4	5.0	22.6	-0.2	-2.6	-1.0	-2.1	-1.5	-4.8	-0.7	-1.7
Exposure to tobacco smoke outside home	2.4	3.2	7.2	-1.3	-2.0	-1.8	-2.7	-0.5	-2.1	-1.3	-1.8
Eye problems/disorders: Cataract	2.4	2.8	13.1	1.7	1.7	3.6	1.5	-0.2	-0.2	0.4	0.7
Neuroticism (Nagel 2018)	2.3	5.4	16.2	2.9	1.9	0.2	2.5	1.9	0.7	4.0	2.2
Hypothyroidism (self reported)	2.3	5.3	14.2	0.6	3.1	2.5	2.5	-0.1	3.8	0.1	2.4
Alcohol usually taken with meals	2.3	3.8	7.9	1.0	1.8	0.8	2.8	0.0	1.9	2.6	2.6
Ever unenthusiastic/disinterested for a whole week	2.3	2.9	5.7	2.3	1.5	0.2	2.1	1.0	0.5	2.4	1.9
Birth weight	2.3	5.0	10.6	1.2	3.0	2.3	2.6	1.8	3.3	1.1	1.7
Number of full brothers	2.3	2.9	6.4	-2.5	-2.0	0.1	-2.1	0.5	-1.2	-1.9	-1.8
Commuting to job workplace: Walk	2.2	2.3	4.3	-2.1	-1.7	-1.5	-1.9	0.9	1.3	-0.2	-1.6
Waist circumference	2.1	7.7	23.8	-3.1	-3.3	-0.7	-2.7	-1.5	-1.4	-4.9	-2.3
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.4	5.0	1.5	1.9	1.9	2.2	-0.4	0.7	0.5	2.0
Pulse wave peak to peak time	2.1	2.5	7.2	0.9	2.1	0.3	1.5	2.1	2.7	0.6	0.5
Bipolar Disorder (2018)	2.0	3.2	7.3	-2.4	-2.7	-1.0	-2.3	-0.6	0.7	-1.2	-1.9
Worry (Nagel 2018)	2.0	4.3	16.2	1.9	1.1	-1.0	1.6	1.6	2.1	4.0	1.6
Chronotype (morning person)	2.0	4.7	15.8	1.2	0.8	1.5	2.3	2.3	0.8	4.0	2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.6	12.5	-0.5	0.7	0.4	1.3	2.1	3.5	0.5	1.1
Bipolar Disorder or Schizophrenia	1.9	4.6	7.6	-2.6	-2.5	-2.1	-2.8	-0.3	0.1	-2.3	-2.4
Wears glasses or contact lenses	1.9	2.2	6.0	1.6	1.1	-0.6	1.7	-1.2	0.8	2.5	1.6
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	3.9	-1.1	-1.6	-1.3	-1.3	1.4	-2.0	-1.3	-1.1
Pulse wave Arterial Stiffness index	1.8	2.1	4.6	-1.0	-2.1	0.1	-1.4	-2.1	-2.1	-0.7	-0.5
Mouth/teeth dental problems: Loose teeth	1.8	2.1	5.1	2.1	2.3	-0.6	1.4	1.7	0.1	0.5	1.3
Illnesses of father: High blood pressure	1.8	2.2	5.5	-1.1	-1.7	-0.8	-2.4	0.3	-1.0	-1.0	-2.2
Happiness	1.7	2.0	7.0	1.3	0.6	0.0	1.5	2.6	-0.1	2.1	0.9
Mouth/teeth dental problems: Mouth ulcers	1.7	2.7	8.0	0.8	2.1	1.4	1.6	1.9	2.8	0.5	0.7
Depression (self-reported)	1.6	1.9	4.2	-1.2	-1.5	-1.5	-0.5	1.8	2.1	0.2	-1.0
Qualifications: O levels/GCSEs or equivalent	1.6	2.5	6.8	-2.0	-0.8	-0.2	-1.7	0.2	2.6	-1.7	-1.7
Depressed Affect (Nagel 2018)	1.5	3.2	7.7	2.0	1.3	0.6	1.9	2.2	0.0	2.8	1.7
Ovarian Cancer	1.5	2.0	5.4	1.2	0.8	-1.4	1.4	1.4	0.1	2.3	1.5
Neuroticism (2016)	1.5	2.1	5.9	1.2	0.8	0.5	1.5	0.5	2.4	2.1	1.3
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	9.7	1.8	0.8	0.8	1.2	1.3	0.4	3.1	1.1
Noisy workplace	1.5	1.9	3.7	-1.3	-1.2	-1.3	-1.6	-1.6	-0.7	-1.9	-1.0
Miserableness	1.5	2.7	5.5	2.2	1.2	0.5	1.9	1.8	-0.1	2.3	1.5
Tinnitus: Yes, now most or all of the time	1.5	1.8	4.1	1.4	1.1	-0.4	2.0	-0.1	-0.1	1.7	2.0
Neuroticism score	1.4	3.0	13.3	1.9	0.9	-0.9	1.4	0.8	1.0	3.6	1.4
Tense / ‘highly strung’	1.4	2.2	7.7	0.7	0.8	0.2	0.7	1.5	2.4	2.8	0.7
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	8.6	0.2	1.8	2.2	1.5	-0.3	2.9	0.4	1.4
Arm fat percentage (left)	1.4	5.6	16.6	-2.2	-2.7	-0.3	-2.5	-1.6	-1.9	-4.1	-1.9
Leg fat percentage (left)	1.4	4.9	11.0	-1.5	-2.6	-0.3	-2.2	-1.6	-3.1	-3.3	-1.7
Qualifications: A levels/AS levels or equivalent	1.3	2.8	9.1	0.4	2.3	1.6	1.3	0.2	3.0	1.4	1.2
Birth weight of first child	1.3	2.4	9.0	0.7	-0.2	1.1	1.8	0.7	3.0	1.6	1.6
Leg fat percentage (right)	1.3	4.7	10.6	-1.5	-2.5	-0.5	-2.2	-1.4	-2.9	-3.3	-1.8
Medication: Allopurinol	1.3	1.7	8.9	1.2	-0.2	0.4	0.6	0.5	0.0	3.0	1.5
Arm fat mass (left)	1.3	5.2	19.5	-2.2	-2.4	0.2	-2.0	-1.6	-1.2	-4.4	-1.8
Type 2 Diabetes (T2D) (2012)	1.2	1.3	2.7	1.3	1.1	-0.9	1.6	-0.2	1.1	1.1	1.4
Bilateral oophorectomy (both ovaries removed)	1.2	1.3	2.9	-1.7	-1.7	0.5	-1.4	0.7	-1.1	-0.1	-1.1
Medication: Atenolol	1.2	1.5	4.2	1.6	0.7	0.4	0.6	-2.0	-1.8	1.0	0.5
Body mass index (BMI)	1.2	5.3	21.4	-1.7	-1.8	-0.2	-1.9	-2.1	-2.0	-4.6	-1.7
Trunk fat mass	1.2	5.1	19.5	-2.1	-2.3	-0.1	-2.0	-1.8	-0.8	-4.4	-1.8
Weight	1.2	5.8	28.5	-2.4	-1.7	0.8	-1.6	-1.9	0.4	-5.3	-1.7
Worrier / anxious feelings	1.2	2.3	11.5	1.5	0.4	-1.1	1.1	-0.3	0.6	3.4	1.4
Arm fat mass (right)	1.2	5.0	22.0	-2.0	-2.1	0.3	-1.8	-1.6	-0.9	-4.7	-1.6
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.1	-1.2	-0.8	0.3	-1.1	0.9	-1.5	-1.8	-1.2
Comparative body size at age 10	1.2	3.4	7.1	1.7	2.7	0.3	2.2	2.1	1.8	-1.5	1.6
Eye problems/disorders: None of the above	1.2	1.4	4.0	-1.5	-0.5	-2.0	-0.9	0.4	1.9	0.2	-0.2
Friendships satisfaction	1.2	1.5	5.1	1.0	0.1	0.4	1.2	1.4	-0.6	2.2	1.3
Hearing aid user	1.2	1.4	2.9	0.3	1.1	0.4	1.5	0.3	1.6	1.5	1.7
Alcohol drinker status: Never	1.2	1.5	3.6	0.2	0.5	1.9	1.3	1.3	1.4	0.7	1.4
Depression (Nagel 2018)	1.1	1.7	6.8	1.1	0.7	1.2	0.9	2.6	0.6	1.5	0.1
Ever used hormone-replacement therapy (HRT)	1.1	1.4	2.5	0.9	0.4	-1.2	1.6	1.5	0.8	1.3	1.4
Maternal smoking around birth	1.1	1.6	3.2	-1.2	-1.3	0.7	-1.6	0.9	-1.7	-0.5	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	4.5	0.2	-1.2	-0.2	-0.8	2.1	-1.3	1.5	-0.9
Arm fat percentage (right)	1.1	4.5	16.0	-1.9	-2.2	-0.2	-2.1	-1.4	-1.5	-4.0	-1.7
Time employed in main current job	1.1	1.2	7.1	1.3	-0.5	-0.1	-0.2	0.2	-2.7	0.7	0.1
Glaucoma (self-reported)	1.1	1.3	8.2	1.1	0.8	0.3	-0.1	-0.1	-2.9	-0.2	-0.3
Number of children fathered	1.1	1.3	2.3	1.0	0.8	1.0	1.2	1.5	0.4	1.5	1.2
Shortness of breath walking on level ground	1.1	1.3	2.4	-0.1	0.9	1.0	1.5	0.9	1.4	1.2	1.5
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	3.5	0.7	0.4	-1.9	1.2	0.0	0.2	1.4	1.6
Commuting to job workplace: Car/motor vehicle	1.1	1.2	7.6	-0.2	-0.3	2.8	-0.1	-0.6	-0.3	-1.1	0.4
Ever had prostate specific antigen (PSA) test	1.1	1.3	6.1	-0.1	-0.0	-1.8	0.5	0.2	2.5	0.9	0.2
Basal cell carcinoma (self-reported)	1.1	1.3	8.3	-1.1	0.5	-0.1	0.5	-0.3	2.9	-0.3	0.7
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	4.5	0.7	0.7	1.7	1.5	0.7	0.5	0.7	2.1
Leg fat mass (left)	1.1	4.1	17.1	-1.6	-1.9	0.3	-1.6	-1.6	-1.6	-4.1	-1.4
Schizophrenia (2018)	1.0	2.0	4.2	-1.3	-1.1	-2.0	-1.7	0.1	-0.4	-2.0	-1.6
Major Depression (MDD)	1.0	1.2	2.2	1.5	1.2	-1.1	1.4	-0.2	0.4	0.8	1.1
Primary Biliary Cirrhosis	1.0	1.4	4.6	-1.3	-0.7	-0.4	-0.9	1.4	2.1	-0.8	-1.2
Ulcerative Colitis	1.0	1.5	4.9	-0.1	-2.2	-0.9	-1.0	1.0	-1.2	1.1	-1.2
BMI	1.0	5.6	27.7	-2.0	-1.2	0.2	-1.6	-2.5	-0.6	-5.3	-1.5
Diabetes (father)	1.0	1.3	2.6	-0.1	-1.1	-1.4	-1.6	-0.2	-0.8	-1.2	-1.5
Leg fat-free mass (left)	1.0	5.1	25.6	-2.2	-0.5	1.5	-0.8	-1.2	2.1	-5.1	-1.3
Trunk fat percentage	1.0	3.8	11.8	-1.7	-2.2	-0.6	-1.9	-1.5	-1.5	-3.4	-1.6
Townsend deprivation index at recruitment	1.0	1.3	2.7	-1.1	-1.1	-1.3	-1.4	-0.5	-0.9	-1.6	-1.0
Fed-up feelings	1.0	1.8	7.3	1.7	1.0	-0.6	0.9	1.0	-0.6	2.7	0.7
Medication: Ramipril	1.0	1.3	3.4	-1.8	-0.8	0.1	-1.6	-0.8	0.9	-0.7	-1.4
Prospective memory result	1.0	1.2	3.1	0.1	0.9	0.7	1.1	1.7	1.8	-0.8	0.9
Medication: Amlodipine	1.0	1.5	4.4	-0.0	-2.0	-0.9	-1.2	-0.9	-2.1	0.0	-0.6
Body fat percentage	1.0	4.1	12.5	-1.6	-2.3	-0.5	-2.0	-1.5	-1.9	-3.5	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	5.9	-0.3	-2.4	-0.6	-0.7	0.4	-1.3	0.4	-0.5
Whole body fat mass	1.0	4.3	17.6	-1.8	-2.1	0.1	-1.8	-1.6	-1.1	-4.2	-1.5
Leg fat mass (right)	1.0	3.7	16.6	-1.5	-1.8	0.2	-1.5	-1.3	-1.4	-4.1	-1.3
Breast cancer (self-reported)	1.0	1.2	3.3	0.9	0.9	0.3	1.3	-0.9	0.9	1.8	1.2
Ever taken oral contraceptive pill	1.0	1.1	3.1	0.6	0.8	-0.1	1.1	1.8	0.9	1.4	0.9
Eye problems/disorders: Glaucoma	1.0	1.2	6.8	0.3	-0.4	-0.9	-0.6	-0.8	-2.6	-0.6	-0.5
Fasting Glucose	0.9	1.1	6.2	0.0	-0.1	-2.5	0.1	0.7	-0.4	1.4	0.1
HDL Cholesterol	0.9	1.6	3.8	0.3	0.2	0.2	1.3	-0.5	1.9	1.9	1.7
Hand grip strength (left)	0.9	2.4	8.4	-1.1	1.3	1.5	0.3	0.9	2.9	-2.1	-0.4
Hand grip strength (right)	0.9	2.5	11.8	-0.9	1.2	1.3	0.9	1.1	3.4	-1.6	0.3
Age when periods started (menarche)	0.9	2.2	10.0	-2.0	-0.4	-0.5	-0.4	1.1	3.2	1.4	-0.4
Leg predicted mass (left)	0.9	5.0	24.7	-2.1	-0.4	1.6	-0.8	-1.2	2.1	-5.0	-1.2
Had other major operations	0.9	1.1	2.0	-1.4	-1.3	-0.1	-1.4	-0.9	0.8	-0.4	-1.2
Hip circumference	0.9	4.0	17.2	-1.4	-1.4	0.7	-1.2	-2.5	-1.2	-4.2	-1.0
Falls in the last year	0.9	1.2	3.0	-1.7	-1.3	0.1	-0.7	-1.0	1.2	-1.4	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	2.6	-1.5	-0.7	-0.5	-0.7	0.7	1.6	-1.2	-0.7
Hair/balding pattern: Pattern 4	0.9	2.3	10.1	0.2	0.5	-0.6	-0.3	-0.1	-2.5	-3.2	-1.1
Blood clot in the leg (DVT)	0.9	1.1	3.7	0.6	0.6	1.4	1.3	0.8	0.4	0.6	1.9
Medication: Paracetamol	0.9	1.5	3.4	-1.0	-1.9	-1.9	-1.2	0.3	1.0	1.3	-0.6
Mean time to correctly identify matches	0.9	1.7	4.3	2.1	1.0	-1.4	1.0	0.2	-0.7	1.9	1.3
Supplements: Vitamin C	0.9	1.1	3.4	0.3	0.7	-0.1	1.4	0.2	0.8	1.4	1.9
Leg fat-free mass (right)	0.9	4.8	23.6	-2.1	-0.3	1.7	-0.6	-1.2	2.1	-4.9	-1.1
Ever had bowel cancer screening	0.9	1.0	3.1	0.2	0.7	0.2	1.1	-0.1	1.8	1.1	1.5
Leg predicted mass (right)	0.9	4.8	23.1	-2.1	-0.3	1.8	-0.6	-1.2	2.1	-4.8	-1.1
Commuting to job workplace: Public transport	0.9	1.1	4.8	-1.3	0.3	0.3	-0.2	-1.2	2.2	-0.7	-0.4
Basal metabolic rate	0.9	5.0	24.1	-2.2	-0.8	1.6	-0.8	-1.3	2.0	-4.9	-1.3
Diastolic blood pressure, automated reading	0.9	2.7	13.0	0.4	-0.4	0.4	-1.1	-2.5	-3.6	-0.9	-0.2
Arm predicted mass (left)	0.9	4.3	20.4	-2.0	-0.7	2.0	-0.6	-1.3	1.6	-4.5	-1.1
Alzheimer’s Disease (in mother)	0.8	1.0	4.0	-0.2	-0.6	-1.2	-0.8	-0.5	-2.0	-1.1	-0.1
Alzheimer’s Disease (including proxy)	0.8	1.2	4.3	-0.3	-1.1	-0.6	-1.1	-0.3	-2.1	-1.4	-0.5
Bipolar Disorder (2011)	0.8	0.8	1.8	-0.8	-1.2	-0.3	-1.4	-0.3	0.8	-0.1	-1.2
Mean Putamen Volume	0.8	1.0	3.9	1.3	0.8	-0.3	0.7	-0.6	-0.1	2.0	0.7
Triglycerides	0.8	1.2	2.1	-1.3	-1.1	0.2	-1.4	0.8	-0.8	-1.3	-1.3
Waist Hip Ratio (WHR)	0.8	3.4	6.6	-2.6	-2.4	-2.2	-2.1	1.6	0.5	-0.6	-1.7
Systolic blood pressure, automated reading	0.8	2.5	8.6	0.7	-0.2	1.5	-0.3	-2.9	-2.9	0.3	0.1
Medication: Co-codamol	0.8	0.9	5.1	0.3	0.4	2.3	-0.3	0.8	-1.0	-0.5	0.1
Diabetes (mother)	0.8	1.0	2.2	-0.5	-0.2	1.4	-0.7	-0.9	-1.1	-1.5	-1.0
Pack years adult smoking proportion	0.8	1.2	3.0	-1.2	-0.9	-0.4	-1.2	-0.2	-1.0	-1.7	-1.3
Hair/balding pattern: Pattern 2	0.8	1.0	5.1	0.2	0.4	-0.8	0.1	0.7	1.1	2.3	0.4
Breastfed as a baby	0.8	1.0	1.8	-1.2	-0.7	-1.4	-0.9	-1.0	1.0	-0.4	-0.9
Arm fat-free mass (right)	0.8	4.1	19.2	-2.0	-1.0	1.8	-0.8	-1.1	1.4	-4.4	-1.2
Medication: Seretide 50 evohaler	0.8	0.9	2.3	-1.1	-1.5	0.2	-1.2	0.6	-0.1	-0.9	-0.9
Arm predicted mass (right)	0.8	4.2	19.7	-2.1	-0.8	1.9	-0.8	-1.2	1.4	-4.4	-1.1
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.3	1.2	1.5	1.0	0.7	-1.2	-0.8	0.7	0.6
Knee pain experienced in last month	0.8	1.3	4.3	0.5	1.3	-1.3	0.8	-1.1	-0.4	-2.1	0.4
Whole body fat-free mass	0.8	4.5	20.9	-2.0	-0.4	1.8	-0.5	-1.1	2.3	-4.6	-1.0
Medication for cholesterol	0.8	1.2	3.5	1.1	1.6	0.4	1.5	0.2	0.0	0.3	1.9
Whole body water mass	0.8	4.7	21.3	-2.0	-0.6	1.8	-0.5	-1.2	2.3	-4.6	-1.1
Average weekly champagne plus white wine intake	0.8	1.1	1.9	1.4	1.1	0.5	1.2	-1.2	-0.0	1.3	1.1
Supplements: Fish oil (including cod liver oil)	0.8	1.1	4.2	2.0	0.1	-0.5	1.0	0.6	-1.4	0.8	0.5
High cholesterol (Self-reported)	0.8	1.5	5.6	0.9	0.5	2.4	1.3	0.1	0.5	1.1	1.5
Ever smoked	0.8	1.3	4.9	1.0	0.5	-0.4	1.2	2.2	1.4	0.6	0.7
Arm fat-free mass (left)	0.8	4.0	19.3	-1.9	-0.7	1.9	-0.5	-1.4	1.4	-4.4	-1.0
Pack years of smoking	0.8	1.1	2.4	-1.0	-0.7	-0.5	-1.2	-0.7	-1.2	-1.5	-1.3
Age at First Birth	0.7	1.0	6.5	-0.7	0.3	0.4	-0.0	-0.3	2.5	-0.4	-0.3
Crohns Disease (2012)	0.7	1.2	5.1	1.3	-0.4	-1.0	0.8	0.6	0.8	2.3	0.5
Lupus	0.7	1.0	2.3	0.8	1.5	1.4	1.0	0.6	0.5	-0.5	1.2
Average weekly spirits intake	0.7	0.8	3.3	-0.2	-0.5	-0.5	-0.3	-1.8	1.3	0.9	-0.5
Sensitivity / hurt feelings	0.7	1.1	4.1	0.5	-0.4	-1.7	0.1	0.4	1.1	2.0	0.6
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	3.9	0.4	0.2	0.0	0.9	0.3	2.0	1.4	1.0
Angina	0.7	1.0	3.7	0.9	0.5	1.0	0.4	1.2	-1.9	0.5	0.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	3.1	0.0	0.3	-1.8	-0.4	0.9	-1.2	-0.1	-0.6
Number of incorrect matches in round	0.7	1.2	4.3	1.0	-0.0	-0.2	0.7	1.6	0.7	2.1	0.7
Had menopause	0.7	0.8	1.8	0.4	0.6	1.2	1.2	-0.5	0.7	0.8	1.4
Medication: Simvastatin	0.7	1.1	2.8	0.0	-0.6	1.6	-0.3	-1.7	-1.5	0.0	-0.4
Fluid intelligence score	0.7	1.4	8.2	-1.0	0.9	0.7	0.3	-0.1	2.9	-0.8	-0.2
Trunk fat-free mass	0.7	3.9	16.1	-1.9	-0.5	1.9	-0.2	-1.0	2.6	-4.0	-0.8
Hair/balding pattern: Pattern 3	0.7	1.0	2.7	1.1	0.2	0.1	1.5	-0.3	0.8	1.6	1.2
Pulse rate	0.7	1.2	4.0	-0.7	-0.6	-2.0	-0.6	1.3	-1.0	-0.0	-1.1
Lung cancer (father)	0.7	0.8	2.6	0.3	0.4	-0.5	-0.5	1.6	1.2	0.5	-1.2
Trunk predicted mass	0.7	4.0	16.2	-1.9	-0.5	1.9	-0.3	-1.0	2.5	-4.0	-0.9
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.5	-1.1	-0.3	-0.8	-1.5	0.4	-0.5	-1.2	-1.9
Medication: Omeprazole	0.7	0.8	2.9	0.3	-0.1	1.3	-0.4	1.7	-1.3	-0.2	-0.1
Qualifications: nursing, teaching	0.7	1.2	4.1	0.3	0.6	-0.2	1.0	-0.9	2.0	1.3	1.1
Mineral and other dietary supplements	0.7	1.0	3.1	-1.8	-0.3	0.2	-1.0	-0.0	1.4	-0.8	-1.1
Medication: Gliclazide	0.7	0.8	4.7	-0.4	0.2	1.1	0.2	2.2	0.4	0.1	-0.0
Medication: Paracetamol	0.7	1.1	1.9	-1.1	-1.4	-1.1	-1.1	0.8	1.1	1.0	-0.7
Intelligence (Savage-Jansen 2018)	0.6	2.0	8.2	-1.2	-0.7	-0.8	-0.7	-1.8	2.9	-1.0	-0.6
Blood Eosinophil Count	0.6	4.3	19.0	-1.1	-0.3	0.5	-1.8	-2.5	0.3	-4.4	-2.0
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.7	0.1	-0.8	0.1	-0.1	1.6	1.0	1.3	-0.5
Impedance of leg (right)	0.6	2.8	15.0	1.4	-0.0	-0.7	0.7	2.0	-0.2	3.9	0.7
Relative age voice broke	0.6	0.9	6.0	-0.3	0.3	-0.6	0.4	0.6	2.5	0.2	0.3
Medication: Levothyroxine sodium	0.6	1.0	3.5	-0.4	0.9	1.2	0.9	-0.9	1.9	-0.5	0.7
Chronic bronchitis/emphysema (father)	0.6	0.7	2.4	-1.1	-0.4	-0.1	-0.7	0.8	0.4	-1.6	-0.5
Impedance of leg (left)	0.6	3.0	16.0	1.5	-0.1	-0.4	0.8	1.9	-0.3	4.0	0.9
Pain all over the body in last month	0.6	0.6	1.7	-0.7	-1.3	1.0	-0.2	0.4	0.5	1.2	0.2
Diabetes (self-reported)	0.6	1.0	1.8	0.9	0.5	1.0	0.7	1.3	0.3	1.2	1.3
Illnesses of siblings	0.6	0.8	2.1	-1.3	0.1	0.2	-0.9	1.4	0.0	-0.3	-1.4
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	6.1	0.1	-0.8	0.1	-0.1	2.5	-0.5	1.1	-0.2
Length of working week for main job	0.6	0.6	3.0	0.1	-0.7	1.7	0.3	-0.2	-0.9	-0.6	0.4
Exposure to tobacco smoke at home	0.6	0.7	3.2	-0.5	-0.3	0.2	-0.5	-0.1	-1.4	-1.8	-0.2
Peak expiratory flow (PEF)	0.6	1.5	5.6	-1.1	-0.1	1.4	0.3	0.0	2.4	-1.7	-0.1
Pulse wave reflection index	0.6	0.8	2.0	-0.5	-0.4	0.4	-0.8	-1.4	-1.4	-1.0	-0.0
Qualifications: College or University degree	0.6	1.9	5.9	-1.1	0.6	1.9	-0.5	-1.3	2.4	-1.4	-0.5
Medication: Ibuprofen	0.6	0.7	1.6	1.3	0.9	0.3	0.8	-1.0	0.0	1.0	0.9
Illnesses of father: Heart disease	0.6	0.8	2.8	-0.1	-1.7	-0.6	-1.0	0.3	-1.2	0.1	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.8	-1.4	-0.4	0.2	-0.4	0.5	2.0	-1.8	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.0	-0.5	-0.9	-1.4	-1.3	0.3	0.1	-0.0	-1.0
Osteoporosis (self-reported)	0.6	0.8	3.3	-0.2	0.5	-0.2	-0.6	-0.5	-0.7	-1.8	-1.2
Medication: Aspirin	0.6	0.8	4.3	0.8	0.5	2.1	0.5	-0.5	-0.6	-0.1	0.4
Number of self-reported non-cancer illnesses	0.6	1.0	3.0	0.8	-0.1	1.4	0.6	0.5	1.3	1.7	0.5
Fractured/broken bones in last 5 years	0.6	0.8	1.4	-1.0	-1.1	-0.4	-0.9	-1.1	0.4	-0.6	-1.2
Age started oral contraceptive pill	0.6	0.7	1.6	-0.9	-1.0	0.3	-0.5	-1.0	1.3	-0.7	-0.5
Commuting to job workplace: Cycle	0.6	0.7	1.8	0.1	1.2	0.0	0.7	-0.4	1.3	1.1	0.7
Alzheimer’s Disease (in father)	0.5	0.5	1.2	-0.9	-1.0	-0.1	-0.8	-0.3	-0.3	-1.1	-0.8
Ulcerative Colitis (UC)	0.5	1.0	2.5	0.2	-1.5	-0.0	-0.8	0.1	-1.6	0.7	-1.3
Verbal and Numeric Reasoning (VNR)	0.5	1.3	9.3	-0.5	0.5	-0.0	0.1	0.0	3.1	-0.4	-0.2
HbA1C	0.5	0.6	1.2	0.7	0.8	1.1	0.9	1.1	0.4	-0.1	0.6
Relative age of first facial hair	0.5	1.0	3.1	-1.2	-1.0	-0.6	-0.4	1.0	1.8	0.7	0.2
Average weekly fortified wine intake	0.5	0.5	1.8	-0.8	-1.3	0.7	-0.8	-0.1	0.4	0.5	-0.7
High blood pressure	0.5	1.5	3.2	1.6	1.4	1.8	1.4	-0.4	0.1	1.1	1.1
Stomach or abdominal pain in last month	0.5	0.6	3.1	0.2	0.6	0.6	0.5	1.0	1.8	0.3	0.3
Supplements: Glucosamine	0.5	0.7	2.6	1.2	-0.0	-0.5	0.3	0.1	-1.6	1.0	0.3
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	11.4	-1.2	-0.2	0.2	0.2	-0.6	3.4	-0.8	0.3
Asthma	0.5	0.9	5.1	0.4	-0.3	0.5	-0.4	-1.2	-2.3	-0.2	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.3	0.8	0.8	-0.6	0.8	-1.1	0.5	0.8	1.0
Standing height	0.5	4.5	24.6	-1.3	0.3	2.4	0.8	0.3	5.0	-1.8	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	4.0	-0.7	-0.7	-0.9	0.3	-0.1	2.0	0.6	0.4
Headache pain in last month	0.5	0.8	1.8	-1.2	-1.0	-0.1	-0.8	0.4	0.5	-0.9	-1.3
Age at first live birth	0.5	0.9	1.7	0.9	1.0	0.7	0.8	-1.0	1.3	1.1	0.6
Emphysema/chronic bronchitis	0.5	0.6	2.6	0.1	-0.7	-0.3	-0.5	1.0	-1.6	0.5	-0.2
Angina (self-reported)	0.5	0.7	3.0	0.7	0.4	0.9	0.3	0.9	-1.7	0.2	-0.2
Heart disease (mother)	0.5	0.6	1.6	0.0	-0.2	0.3	0.7	-1.2	1.0	0.5	1.1
Alcohol intake frequency.	0.5	1.1	3.9	-0.6	-1.0	-0.4	-0.9	0.2	-1.6	-2.0	-0.6
Suffer from ‘nerves’	0.5	0.8	2.9	1.1	0.8	-0.4	0.9	0.3	0.5	1.7	0.7
Overall health rating	0.5	1.0	2.4	-0.7	-1.6	-0.9	-1.1	1.3	-1.2	0.3	-0.5
Medication: Aspirin	0.5	0.6	4.0	0.7	0.4	2.0	0.2	-0.1	-0.7	0.1	0.2
Hypertension (Self-reported)	0.5	1.4	2.7	1.5	1.2	1.6	1.4	0.1	-0.2	1.3	1.1
Illnesses of siblings: Diabetes	0.5	0.7	1.2	0.9	-0.0	1.0	1.1	-1.0	0.5	0.5	0.9
Average weekly red wine intake	0.5	0.7	2.8	-0.6	-0.1	1.0	0.6	-0.1	1.7	0.8	0.9
Mood swings	0.5	0.8	3.2	-0.1	-0.1	-0.6	0.3	1.7	-0.2	1.8	0.2
Medication: Blood pressure	0.5	0.9	3.0	-0.8	-0.3	0.7	-1.2	-0.4	-0.4	-1.1	-1.7
Number of operations (self-reported)	0.5	0.8	2.5	-0.1	-0.7	1.3	0.0	-0.5	1.2	1.6	0.2
Vascular/heart problems diagnosed by doctor	0.5	1.3	3.1	-1.6	-1.0	-1.8	-1.3	0.2	0.2	-1.1	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.7	0.3	0.1	1.3	-0.4	1.0	-1.2	-0.6	-0.3
Supplements: Calcium	0.5	0.5	1.5	-0.0	0.5	-0.2	1.2	0.1	0.7	0.4	1.2
Impedance of whole body	0.5	2.7	15.1	1.1	0.2	-0.3	0.7	1.8	0.7	3.9	0.9
Schizophrenia (2014)	0.4	0.8	2.1	-0.9	-0.5	-0.9	-1.0	0.2	-0.3	-1.4	-1.1
Blood White Count	0.4	3.0	5.8	-1.4	-2.1	-0.9	-2.0	-0.6	-1.8	-2.4	-1.7
Systolic Blood Pressure	0.4	2.1	7.7	0.8	0.2	2.8	0.2	-1.5	-2.0	1.5	0.6
Ever had hysterectomy (womb removed)	0.4	0.4	1.4	-1.2	0.2	0.1	-0.5	-0.3	-0.3	-1.2	-0.4
Medication for hormone replacement therapy	0.4	0.4	1.6	-0.4	-0.4	-0.8	-0.3	1.3	0.5	-0.2	-0.5
Vitamin and mineral supplements	0.4	0.5	1.7	-0.8	0.1	-0.5	-0.9	-0.1	0.1	-1.0	-1.3
Supplements: Zinc	0.4	0.5	1.0	1.0	0.4	-0.9	0.6	-0.4	-0.4	0.7	0.7
Current tobacco smoking	0.4	0.6	2.0	0.7	0.6	1.2	0.2	1.4	-0.7	0.1	0.3
Taking other prescription medications	0.4	0.6	2.7	0.6	-0.3	-0.4	0.5	0.5	0.8	1.7	0.4
Hayfever, allergic rhinitis or eczema	0.4	0.9	3.3	-0.6	-0.9	0.7	-0.8	-1.1	1.8	-0.3	-0.7
Multivitamins +/- minerals	0.4	0.5	1.3	1.0	0.3	0.8	1.1	0.2	0.1	0.4	0.9
Sitting height	0.4	2.8	6.5	-1.4	-0.3	2.0	-0.7	-2.0	2.1	-2.5	-1.0
High blood pressure (mother)	0.4	0.5	2.8	-0.3	0.5	0.4	-0.1	-0.7	-0.5	-1.7	0.2
Past tobacco smoking	0.4	0.8	2.1	-1.0	-0.4	0.6	-1.4	-0.7	-0.8	-0.3	-1.1
Forced vital capacity (FVC)	0.4	1.7	11.6	-0.8	0.2	0.0	0.2	-0.5	3.4	-0.7	0.3
Impedance of arm (right)	0.4	2.0	9.0	1.2	0.7	-0.2	0.9	1.5	1.1	3.0	1.0
Number of live births	0.4	0.6	1.1	0.7	0.9	1.1	0.6	0.9	-0.1	0.7	0.5
Medication: Lansoprazole	0.4	0.5	2.3	-0.6	-0.9	-1.5	-0.3	0.1	-0.1	-0.6	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	6.5	-1.4	-0.7	-0.1	-0.2	-0.7	2.5	-0.8	0.1
Impedance of arm (left)	0.4	1.7	9.5	0.5	-0.1	-0.4	0.4	1.4	1.0	3.1	0.7
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.3	0.5	0.7	0.4	0.1	1.1	-0.6	1.1	0.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.3	-0.8	-0.3	0.0	-0.3	-0.7	1.5	-0.2	-0.6
Gout (self-reported)	0.4	0.6	1.5	0.8	0.2	0.3	0.7	0.8	0.4	1.2	1.0
Medication for pain relief, constipation, heartburn	0.4	0.6	1.2	-0.9	-0.9	-0.1	-0.6	0.0	-1.0	-1.1	-0.9
Medication: Blood pressure	0.4	0.7	1.9	1.0	0.2	0.8	0.8	-0.6	-0.3	0.9	1.4
Family relationship satisfaction	0.4	0.5	1.2	0.3	-0.0	1.1	0.4	1.1	-0.5	-0.0	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.0	1.0	0.6	-0.7	0.6	0.7	-0.5	-0.6	0.4
Loneliness, isolation	0.4	0.5	1.0	0.3	0.6	-0.9	0.7	0.6	1.0	0.8	0.6
Long-standing illness, disability or infirmity	0.4	0.6	2.8	0.1	-0.9	-0.0	-0.2	1.0	0.7	1.7	-0.2
Diabetes diagnosed by doctor	0.4	0.6	2.3	-0.1	-0.7	0.5	-0.4	1.5	-0.5	1.1	0.4
Asthma (self-reported)	0.4	0.9	3.8	0.6	-0.0	0.6	-0.1	-1.5	-1.9	0.1	-0.1
Smoking status: Current	0.4	0.6	2.0	0.7	0.3	1.3	0.1	1.4	-0.7	0.2	0.3
Financial situation satisfaction	0.4	0.5	1.9	0.8	-0.1	-0.3	0.6	1.4	0.3	0.9	-0.3
Medication: Lisinopril	0.4	0.5	2.8	0.3	-1.7	0.3	-0.4	0.1	-1.0	0.4	-0.2
Medication: Atorvastatin	0.4	0.5	2.2	-0.1	-0.1	0.5	0.2	1.5	-1.0	-0.3	0.5
Irritability	0.4	0.6	2.7	0.7	1.1	0.1	0.5	0.1	0.1	1.7	0.5
Risk taking	0.4	0.5	1.2	-1.1	-0.2	-0.3	-0.6	0.2	1.0	-0.9	-0.7
Myopia	0.4	0.6	2.8	0.3	0.2	-1.3	0.0	-1.7	0.6	0.2	0.1
Alcohol drinker status: Previous	0.4	0.4	1.3	-0.2	-0.6	-1.1	-0.4	0.5	-1.0	-0.3	-0.3
Crohns Disease (2017)	0.3	0.8	2.3	1.5	0.4	0.4	0.9	-0.4	-0.7	1.3	0.6
Irritable Bowel Disease (IBD)	0.3	0.7	2.1	1.0	-0.8	0.2	-0.1	0.2	-1.4	1.3	-0.5
Reaction Time	0.3	0.6	1.9	1.2	0.8	-1.4	0.3	0.1	-0.7	0.3	0.2
Coronary Artery Disease (CAD)	0.3	0.4	2.4	-0.4	0.3	1.5	0.5	-0.4	-0.0	0.3	0.4
Rheumatoid Arthritis	0.3	0.4	1.2	0.8	0.1	0.2	0.3	-0.3	-0.2	0.9	1.1
Blood Platelet Count	0.3	3.4	9.4	-1.7	-2.2	-3.1	-2.2	-0.3	-1.4	-0.4	-1.7
Allergy or Eczema	0.3	0.8	3.6	0.2	-0.3	0.5	-0.1	-1.6	1.9	0.5	-0.2
Tanning	0.3	3.2	6.0	-1.6	-2.0	-1.7	-2.5	-0.4	-1.6	-1.4	-2.3
Number of treatments/medications taken	0.3	0.5	2.4	1.0	-0.2	-0.1	0.3	-0.0	0.7	1.6	0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.9	0.3	0.2	-0.6	-0.1	-0.1	-0.5	1.4	0.2
High blood pressure (siblings)	0.3	0.4	1.1	0.8	-0.2	-0.8	0.6	-0.5	0.1	0.3	1.1
Forced vital capacity (FVC), Best measure	0.3	1.0	6.2	-0.6	-0.1	0.2	0.1	-0.7	2.5	-0.7	0.2
Wheeze or whistling in the chest in last year	0.3	0.5	2.2	0.8	0.2	0.6	0.3	-0.2	-1.5	0.6	0.2
Pulse rate, automated reading	0.3	0.8	1.7	-1.1	-1.3	-0.6	-0.9	1.1	-0.2	-0.2	-1.0
Comparative height size at age 10	0.3	1.6	3.3	0.3	0.5	1.8	1.7	0.6	1.8	-1.2	1.2
Leg pain on walking	0.3	0.3	1.4	0.4	0.4	-0.3	0.7	-0.0	0.2	0.6	1.2
Smoking status: Previous	0.3	0.5	1.6	0.6	0.5	-0.7	1.3	-0.4	0.6	0.0	0.9
Osteoarthritis (self-reported)	0.3	0.4	2.6	-0.3	-0.3	-0.5	-0.2	0.5	-0.3	-1.6	0.0
Illnesses of father: None of the above (group 1)	0.3	0.4	2.5	-0.3	0.3	-0.4	0.4	-0.2	0.2	1.6	0.5
Mother’s age at death	0.3	0.4	0.8	0.6	0.9	-0.7	0.4	-0.6	-0.2	-0.2	-0.9
Unable to work because of sickness or disability	0.3	0.4	1.0	-0.9	-1.0	-0.4	-1.0	0.5	0.3	0.3	-0.3
Cholesterol lowering medication	0.3	0.5	3.1	-0.3	0.0	1.8	-0.4	-0.4	0.0	0.1	-0.5
Pain experienced in last month	0.3	0.5	1.3	-0.8	-0.7	-0.3	-1.1	-0.5	0.9	0.0	-0.9
Breast Cancer	0.2	0.4	2.5	0.4	-0.1	0.1	0.6	0.4	1.6	0.1	0.6
Body Mass Index (BMI) (2010)	0.2	0.2	0.8	0.4	0.9	0.0	0.5	-0.3	0.3	-0.6	0.1
LDL Cholesterol	0.2	0.3	1.1	-0.3	0.7	-0.1	0.1	-0.4	1.0	-0.2	0.7
Height	0.2	3.9	25.1	-1.2	-0.5	0.8	0.9	-0.0	5.0	-1.5	0.5
Cardiovascular Disease	0.2	0.8	4.4	-0.1	-0.4	2.1	0.3	0.1	1.0	0.1	0.7
Respiratory disease	0.2	0.4	1.3	0.4	-0.5	-0.0	-0.2	-0.7	-1.1	1.1	0.3
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.9	-0.9	-0.5	0.4	-0.9	0.9	0.1	0.2	-0.1
Lung FEV1/FVC ratio	0.2	0.8	1.8	-1.1	-1.4	-0.5	-0.5	-1.1	0.1	-1.2	-0.2
Lung FVC	0.2	0.8	2.2	1.5	0.8	-0.6	0.8	-0.9	0.4	0.7	1.1
Severe depression (siblings)	0.2	0.3	1.0	0.5	-0.0	-0.8	0.2	-0.4	0.2	1.0	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.0	-0.4	1.0	0.1	-0.5	-0.3	0.7	-0.9	-0.9
Serious illness, injury or assault to yourself	0.2	0.3	1.1	-0.4	-0.6	0.0	0.4	0.6	1.0	-0.3	0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	-0.4	-0.4	-0.7	0.3	-0.7	0.2	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	2.7	0.6	1.6	0.0	-0.1	-0.5	0.2	-0.4	-0.3
Financial difficulties in last 2 years	0.2	0.2	0.8	-0.2	-0.5	0.2	0.1	0.7	-0.4	-0.9	-0.1
Mouth/teeth dental problems	0.2	0.3	0.9	0.5	0.1	-0.4	0.3	-0.7	-1.0	0.8	0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.7	-0.1	-0.8	0.8	0.1	-0.1	0.6	-0.4	0.4
Father’s age at death	0.2	0.3	0.7	0.1	0.1	-0.8	0.4	-0.2	-0.4	0.7	0.7
Mouth/teeth dental problems: Dentures	0.2	0.3	0.6	0.4	-0.5	0.7	0.0	-0.1	-0.7	0.2	0.7
Medication: Cholesterol lowering	0.2	0.3	0.7	0.6	-0.8	0.4	0.4	0.0	-0.2	0.7	0.5
Illnesses of mother	0.2	0.3	0.6	-0.3	-0.3	0.8	-0.3	0.7	0.8	0.2	-0.5
Loud music exposure frequency	0.2	0.3	1.3	-0.4	-0.6	-0.1	-0.1	-0.5	1.1	0.1	-0.0
Neck or shoulder pain in last month	0.2	0.2	0.7	0.3	0.2	-0.8	-0.1	0.6	-0.3	-0.8	-0.1
Migraine (self-reported)	0.2	0.2	1.2	0.1	0.1	0.1	0.4	-0.5	1.1	-0.1	0.5
Chest pain or discomfort	0.2	0.3	0.6	0.2	0.7	0.7	0.7	0.1	0.7	0.1	0.8
Had major operations	0.2	0.2	1.0	0.5	0.1	-0.4	0.1	-1.0	-0.5	-0.2	0.2
Age at last live birth	0.2	0.3	0.9	0.3	0.4	0.9	-0.1	-0.2	0.9	0.4	0.1
Back pain experienced in last month	0.2	0.3	0.6	0.6	0.4	-0.3	0.8	-0.3	-0.6	-0.7	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	1.6	-0.7	-0.6	-0.1	-0.1	0.2	1.3	-0.5	0.1
Heart disease (siblings)	0.2	0.3	0.9	0.4	-0.6	0.0	-0.2	-0.9	-0.3	-0.8	-0.0
Heel T-Score	0.1	1.1	4.0	1.5	2.0	0.8	1.0	-0.3	-0.0	0.5	0.6
Smoking Status	0.1	0.3	0.5	0.2	0.3	0.7	0.7	0.5	-0.1	-0.5	0.7
Medication: Metformin	0.1	0.2	0.7	-0.2	-0.0	0.8	-0.2	0.8	-0.1	-0.4	0.3
Qualifications: CSEs or equivalent	0.1	0.2	0.6	0.2	0.2	0.8	0.3	0.1	-0.7	-0.1	0.5
Heart attack	0.1	0.2	0.5	-0.2	0.2	0.3	0.5	0.7	0.4	-0.1	0.0
Allergy	0.1	0.3	0.7	-0.6	0.4	-0.8	-0.0	0.7	-0.2	-0.7	-0.2
Number of full sisters	0.1	0.2	0.9	-0.3	0.5	0.2	0.2	0.9	-0.4	-0.0	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.4	0.0	0.4	0.1	0.2	-0.6	-0.6	-0.3	0.3
Medication: Bendroflumethiazide	0.1	0.1	0.4	0.2	-0.2	-0.4	0.3	0.0	-0.6	0.6	0.4
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.6	-0.1	0.3	0.4	0.5	0.7	0.4	-0.2	-0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.2	1.0	0.2	-0.5	-0.1	0.4	-1.0	0.4	-0.6	0.0
Hair Pigment	0.0	0.7	2.2	1.0	0.4	0.6	1.1	-0.6	0.3	0.6	1.5

Hub : Genes

SRSF12

Models

Trait associations