TWAS hub - PTGER4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.054	0.0260	0.0059	0.064	NA	0.035	NA	0.042	1.5e-05	NA	1.1e-03	NA	3.9e-04
2	YFS	Blood	0.188	0.0323	0.0000	0.091	0.148	0.170	0.156	0.161	3.0e-28	4.5e-46	2.8e-53	1.6e-48	3.3e-50

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Crohns Disease (2017)	22.2	48.8	86.9	9.3	3.3
Crohns Disease (2012)	20.5	33.1	49.1	7.0	4.1
Irritable Bowel Disease (IBD)	11.6	27.6	42.9	6.5	3.5
Medication: Ramipril	6.4	8.2	12.2	-3.5	-2.1
Supplements: Zinc	4.6	5.0	9.1	-0.9	-3.0
Hayfever, allergic rhinitis or eczema	4.6	10.0	19.3	4.4	0.8
Back pain experienced in last month	3.8	5.5	6.6	-2.1	-2.6
Allergy	3.6	8.3	16.0	-4.0	-0.8
Shortness of breath walking on level ground	3.6	4.3	5.9	1.6	2.4
Supplements: Vitamin C	3.6	4.2	6.7	2.6	-1.3
Allergy or Eczema	3.4	8.9	17.6	4.2	0.4
Medication: Gliclazide	3.2	3.6	6.7	-2.6	-0.7
Alzheimer’s Disease (in father)	3.1	3.3	6.4	-0.5	-2.5
Medication: Lansoprazole	3.1	3.5	7.0	-0.2	2.6
Time employed in main current job	2.9	3.3	4.2	-2.0	-1.6
Risk taking	2.8	4.0	7.8	2.8	0.5
Serious illness, injury or assault to yourself	2.6	3.1	3.6	1.9	1.6
Ulcerative Colitis	2.5	3.7	7.1	0.5	2.7
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.1	5.9	0.6	2.4
Medication: Seretide 50 evohaler	2.5	2.9	5.7	2.4	0.1
Pain all over the body in last month	2.3	2.5	3.7	1.9	1.1
Medication: Simvastatin	2.1	3.0	4.7	-2.2	-1.2
Exposure to tobacco smoke outside home	2.1	2.7	3.7	1.9	1.3
Alcohol intake versus 10 years previously	2.0	2.9	4.7	2.2	1.1
Worry too long after embarrassment	1.9	3.2	4.3	-1.4	-2.1
Schizophrenia vs Biploar Disorder	1.8	2.4	2.8	-1.5	1.7
Severe depression (siblings)	1.8	2.1	4.0	-0.4	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	3.1	-0.8	-1.8
Friendships satisfaction	1.8	2.2	3.8	2.0	-0.8
Mean Putamen Volume	1.7	1.9	3.8	-0.1	-2.0
Respiratory disease	1.7	3.8	7.5	2.7	0.3
Medication: Metformin	1.7	2.4	2.4	-1.6	-1.5
Average weekly fortified wine intake	1.7	2.0	3.5	1.9	0.7
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	4.1	2.0	0.6
Wheeze or whistling in the chest in last year	1.7	3.0	3.5	1.9	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	3.7	-1.9	0.6
Medication: Atorvastatin	1.7	2.2	2.6	1.6	1.3
Tense / ‘highly strung’	1.6	2.7	4.3	-2.1	-1.1
Mother’s age at death	1.6	2.0	2.6	1.6	1.2
Medication for pain relief, constipation, heartburn	1.5	2.5	5.0	0.1	-2.2
Migraine (self-reported)	1.5	1.9	3.6	0.4	1.9
Medication: Ibuprofen	1.5	1.8	3.5	0.3	1.9
LDL Cholesterol	1.4	2.2	3.9	-2.0	0.7
Primary Biliary Cirrhosis	1.4	2.0	4.0	0.1	2.0
Sensitivity / hurt feelings	1.4	2.5	4.4	-0.7	-2.1
Hair/balding pattern: Pattern 2	1.4	1.8	3.5	-0.3	1.9
Peak expiratory flow (PEF)	1.4	3.2	5.9	0.8	-2.4
Eye problems/disorders: None of the above	1.4	1.6	3.1	1.8	0.4
Verbal and Numeric Reasoning (VNR)	1.3	3.2	3.3	1.8	1.7
Lupus	1.3	2.0	3.2	-0.9	-1.8
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	8.7	0.2	-3.0
Qualifications: A levels/AS levels or equivalent	1.3	2.9	3.8	2.0	1.4
Mouth/teeth dental problems: Dentures	1.3	2.1	4.2	-2.1	0.1
Pulse wave reflection index	1.3	1.7	2.4	-0.9	-1.6
Medication: Paracetamol	1.3	2.2	3.7	-0.8	1.9
Medication: Blood pressure	1.3	2.3	3.9	-2.0	-0.8
Illnesses of father: Heart disease	1.3	1.8	3.5	-0.4	1.9
Handedness (chirality/laterality): Left-handed	1.3	1.5	2.7	0.6	1.6
Osteoporosis (self-reported)	1.3	1.6	3.0	1.7	-0.4
Miserableness	1.3	2.2	3.5	1.9	1.0
Pain type(s) experienced in last month: Hip pain	1.3	1.6	2.2	1.5	-1.0
Alzheimer’s Disease (in mother)	1.2	1.4	2.7	-1.6	0.4
Ulcerative Colitis (UC)	1.2	2.3	3.2	1.2	1.8
Blood Platelet Count	1.2	14.0	19.9	4.5	2.8
Blood Red Count	1.2	11.8	23.5	-4.8	0.1
Number of children fathered	1.2	1.3	2.6	1.6	-0.3
Family relationship satisfaction	1.2	1.4	1.7	1.1	-1.3
Mineral and other dietary supplements	1.2	1.6	2.1	-1.4	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	4.4	-0.9	-2.1
Depression (Nagel 2018)	1.1	1.7	3.3	0.2	1.8
Fasting Glucose	1.1	1.4	1.7	1.3	1.0
HbA1C	1.1	1.3	1.8	1.3	-0.9
Chronotype (morning person)	1.1	2.6	2.7	-1.6	-1.6
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	2.2	0.7	1.5
Multivitamins +/- minerals	1.1	1.4	1.9	1.4	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.7	6.3	1.0	-2.5
Headache pain in last month	1.1	1.9	3.6	-0.4	1.9
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.5	1.6	-0.4
Eye problems/disorders: Cataract	1.1	1.3	2.4	-1.6	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.4	1.6	0.5
Medication: Paracetamol	1.1	1.7	3.4	-0.2	1.9
Ever had prostate specific antigen (PSA) test	1.1	1.3	1.9	0.9	1.4
Type 2 Diabetes (T2D) (2012)	1.0	1.1	1.9	-0.6	-1.4
Waist Hip Ratio (WHR)	1.0	4.7	7.8	-1.2	-2.8
Hair/balding pattern: Pattern 3	1.0	1.5	2.0	-1.0	-1.4
Length of working week for main job	1.0	1.1	1.8	1.3	0.6
Gout (self-reported)	1.0	1.4	2.5	1.6	0.5
Suffer from ‘nerves’	1.0	1.5	2.9	0.4	1.7
Supplements: Fish oil (including cod liver oil)	1.0	1.3	1.8	1.4	-0.9
Prostate Cancer	0.9	1.2	1.3	1.1	1.1
Medication for hormone replacement therapy	0.9	1.0	1.3	-0.8	-1.1
Forced vital capacity (FVC)	0.9	3.5	7.0	0.1	-2.6
Lung cancer (father)	0.9	1.1	2.0	-0.5	1.4
Birth weight	0.9	2.0	3.8	1.9	-0.3
Average weekly champagne plus white wine intake	0.9	1.2	2.4	-0.1	-1.6
Supplements: Calcium	0.9	1.0	1.2	1.1	-0.9
Hand grip strength (left)	0.8	2.0	3.2	1.8	0.9
Alcohol usually taken with meals	0.8	1.3	1.4	1.2	1.0
Mouth/teeth dental problems	0.8	1.3	2.5	1.6	-0.1
Fluid intelligence score	0.8	1.6	2.5	0.8	1.6
Number of live births	0.8	1.2	2.4	0.0	-1.5
Exposure to tobacco smoke at home	0.8	0.9	1.4	-1.2	0.6
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	2.4	1.5	0.4
Asthma (self-reported)	0.8	1.5	3.0	1.7	-0.2
Hearing aid user	0.8	0.9	1.4	1.2	0.6
Medication: Lisinopril	0.8	1.0	1.3	1.1	0.8
Cholesterol lowering medication	0.8	1.3	2.4	-1.6	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.0	-1.4	0.1
Reaction Time	0.7	1.4	2.5	0.5	1.6
Ovarian Cancer	0.7	1.0	1.8	1.3	0.4
Bipolar Disorder (2011)	0.7	0.7	1.1	1.1	-0.5
Neuroticism (2016)	0.7	1.0	1.4	1.2	0.8
Rheumatoid Arthritis	0.7	0.9	1.1	-1.1	0.8
Hearing difficulty/problems: Yes	0.7	1.1	1.8	0.6	-1.3
Relative age voice broke	0.7	1.0	2.0	1.4	0.3
Medication: Atenolol	0.7	0.8	1.0	-1.0	0.8
High blood pressure (mother)	0.7	1.0	1.1	-1.1	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	1.7	1.3	0.9
Asthma	0.7	1.4	2.6	1.6	-0.3
Mouth/teeth dental problems: Loose teeth	0.7	0.8	0.9	-0.8	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.6	-0.1	-1.3
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.7	-1.3	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.1	-1.4	-1.0
Medication for cholesterol	0.7	1.1	1.6	0.7	1.3
Myopia	0.7	1.0	1.8	-0.5	-1.3
Type 2 Diabetes (T2D) (2018)	0.6	1.2	2.4	-1.6	0.0
Vitamin and mineral supplements	0.6	0.9	1.7	-1.3	0.2
Current tobacco smoking	0.6	1.0	1.8	-0.4	1.4
Chronic bronchitis/emphysema (father)	0.6	0.7	1.4	0.0	-1.2
Number of incorrect matches in round	0.6	1.0	1.1	1.0	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.1	0.6	-1.0
Depression (self-reported)	0.6	0.8	1.0	-0.7	1.0
Breastfed as a baby	0.6	0.7	1.0	0.6	-1.0
Chronic bronchitis/emphysema (mother)	0.6	0.8	1.3	1.1	0.5
Number of full sisters	0.6	0.7	1.1	1.0	0.6
Mood swings	0.6	1.1	1.6	1.3	0.7
Diabetes diagnosed by doctor	0.6	1.0	1.8	-1.3	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.8	0.0	1.4
Breast cancer (self-reported)	0.6	0.8	1.4	-0.4	1.2
Smoking status: Current	0.6	1.0	1.7	-0.6	1.3
Medication: Bendroflumethiazide	0.6	0.9	0.9	-0.9	-1.0
Number of operations (self-reported)	0.6	0.9	1.6	0.4	-1.3
Body Mass Index (BMI) (2010)	0.5	0.6	1.2	-1.1	0.3
Blood White Count	0.5	3.6	6.8	-0.6	2.6
Lung FEV1/FVC ratio	0.5	2.4	4.8	-0.0	-2.2
Age when periods started (menarche)	0.5	1.2	2.4	0.1	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	1.3	1.2	1.0
Had menopause	0.5	0.7	1.2	1.1	0.3
Diabetes (self-reported)	0.5	0.8	1.4	-1.2	0.4
Falls in the last year	0.5	0.6	0.9	0.6	-0.9
Prospective memory result	0.5	0.6	0.7	-0.9	-0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.2	-0.1	1.1
Forced vital capacity (FVC), Best measure	0.5	1.7	3.0	0.7	-1.7
Medication: Allopurinol	0.5	0.6	1.0	1.0	0.5
Alcohol intake frequency.	0.5	1.2	2.1	1.5	0.6
Average weekly red wine intake	0.5	0.8	1.3	0.5	1.2
Osteoarthritis (self-reported)	0.5	0.7	1.3	1.1	-0.2
Number of self-reported non-cancer illnesses	0.5	0.9	1.7	-0.3	-1.3
Guilty feelings	0.5	0.8	1.3	1.1	-0.6
Age at First Birth	0.4	0.6	0.8	-0.5	0.9
Coronary Artery Disease (CAD)	0.4	0.5	0.6	-0.7	-0.6
Triglycerides	0.4	0.6	0.9	1.0	0.6
Lung FVC	0.4	2.1	4.1	0.0	-2.0
Average weekly spirits intake	0.4	0.4	0.9	0.0	0.9
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.0	0.2	1.0
Pack years adult smoking proportion	0.4	0.6	0.8	0.7	0.9
Fed-up feelings	0.4	0.6	1.2	-1.1	-0.3
Nervous feelings	0.4	0.7	1.0	-0.7	-1.0
Hearing difficulty/problems with background noise	0.4	0.6	1.3	0.0	-1.1
Happiness	0.4	0.5	0.9	-0.1	-1.0
Illnesses of mother	0.4	0.5	0.9	1.0	0.2
Pulse wave Arterial Stiffness index	0.4	0.4	0.8	0.4	-0.9
Birth weight of first child	0.4	0.7	1.3	1.1	0.3
Loud music exposure frequency	0.4	0.5	1.0	0.0	1.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.3	1.2	0.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.8	0.9	-0.4
High blood pressure (siblings)	0.4	0.6	1.0	0.4	1.0
Comparative body size at age 10	0.4	1.1	2.0	-1.4	-0.6
Qualifications: College or University degree	0.4	1.3	1.4	1.2	1.1
Medication: Omeprazole	0.4	0.5	0.9	-1.0	0.0
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.7	0.4	-0.8
Illnesses of father: None of the above (group 1)	0.4	0.5	0.9	0.2	1.0
Wears glasses or contact lenses	0.4	0.5	0.7	-0.5	-0.8
High cholesterol (Self-reported)	0.4	0.6	1.2	-1.1	-0.3
Pack years of smoking	0.4	0.6	0.7	0.7	0.8
Intelligence (Savage-Jansen 2018)	0.3	1.1	1.3	1.1	0.9
Alzheimer’s Disease (including proxy)	0.3	0.4	0.9	-0.9	0.1
Systolic Blood Pressure	0.3	1.3	1.8	-0.8	-1.4
Neuroticism	0.3	0.6	0.9	-0.6	1.0
Number of treatments/medications taken	0.3	0.5	0.9	-0.9	0.5
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.4	-0.6	-0.6
Ever had hysterectomy (womb removed)	0.3	0.3	0.6	0.0	0.8
Angina	0.3	0.4	0.7	0.4	0.8
Impedance of leg (right)	0.3	1.6	2.2	1.0	1.5
Hand grip strength (right)	0.3	0.9	1.6	1.3	0.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.4	-0.5	-0.6
High blood pressure	0.3	0.8	1.4	-0.6	-1.2
Stomach or abdominal pain in last month	0.3	0.4	0.7	0.8	-0.4
Impedance of leg (left)	0.3	1.4	1.5	1.1	1.2
Had other major operations	0.3	0.3	0.5	0.7	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.6	1.2	0.2
Qualifications: None of the above	0.3	0.5	1.1	-1.0	-0.1
Financial difficulties in last 2 years	0.3	0.4	0.7	0.4	0.8
Heart attack	0.3	0.3	0.7	-0.0	0.8
Medication: Amlodipine	0.3	0.5	0.7	0.8	0.5
Leg fat percentage (right)	0.3	1.0	2.1	0.1	1.4
Number of full brothers	0.3	0.4	0.5	0.7	-0.7
Pulse wave peak to peak time	0.3	0.4	0.7	-0.3	0.8
Neck or shoulder pain in last month	0.3	0.4	0.8	-0.1	0.9
Overall health rating	0.3	0.6	1.2	-0.2	-1.1
Knee pain experienced in last month	0.3	0.4	0.5	0.7	0.6
Long-standing illness, disability or infirmity	0.3	0.4	0.8	0.9	-0.0
Commuting to job workplace: Walk	0.3	0.3	0.6	0.2	0.8
Financial situation satisfaction	0.3	0.4	0.8	0.2	-0.9
Commuting to job workplace: Public transport	0.3	0.3	0.4	-0.5	-0.7
Unable to work because of sickness or disability	0.3	0.3	0.6	0.3	-0.8
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.4	0.3	1.2
Pain experienced in last month	0.3	0.4	0.6	0.8	0.5
Alcohol drinker status: Previous	0.3	0.3	0.7	0.8	-0.1
Bipolar Disorder (2018)	0.2	0.3	0.6	-0.3	-0.7
Worry (Nagel 2018)	0.2	0.4	0.6	-0.8	0.5
Tanning	0.2	2.6	5.1	0.3	-2.3
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.3	-0.6	0.2
Diabetes (father)	0.2	0.2	0.4	0.0	-0.7
Diabetes (mother)	0.2	0.3	0.4	-0.3	-0.6
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	0.4	-0.5
Supplements: Glucosamine	0.2	0.3	0.3	0.5	-0.5
Hip circumference	0.2	1.0	1.1	0.9	1.1
Medication: Cholesterol lowering	0.2	0.2	0.3	-0.4	0.6
Blood clot in the leg (DVT)	0.2	0.2	0.4	0.6	0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.6	-0.8	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.4	0.6	-0.1
Hypertension (Self-reported)	0.2	0.6	1.2	-0.3	-1.1
Illnesses of siblings: Diabetes	0.2	0.2	0.2	0.4	-0.5
Loneliness, isolation	0.2	0.2	0.4	-0.6	-0.3
Medication: Aspirin	0.2	0.2	0.4	0.2	0.6
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.3	-0.5	-0.4
Eye problems/disorders: Glaucoma	0.2	0.2	0.2	-0.5	0.4
Medication: Blood pressure	0.2	0.3	0.6	-0.2	-0.8
Illnesses of father: High blood pressure	0.2	0.3	0.4	0.6	-0.5
Leg fat percentage (left)	0.2	0.7	1.3	0.3	1.2
Average weekly beer plus cider intake	0.2	0.3	0.4	0.7	0.4
Fractured/broken bones in last 5 years	0.2	0.3	0.4	-0.6	0.4
Ever depressed for a whole week	0.2	0.3	0.5	-0.7	-0.3
Commuting to job workplace: Cycle	0.2	0.3	0.4	0.4	0.6
Basal cell carcinoma (self-reported)	0.2	0.3	0.4	0.7	-0.3
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.5	-0.4	0.7
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.4	0.7	-0.1
Depressed Affect (Nagel 2018)	0.1	0.3	0.5	0.7	0.4
Schizophrenia (2018)	0.1	0.2	0.3	-0.3	0.5
Major Depression (MDD)	0.1	0.1	0.1	-0.0	0.4
Breast Cancer	0.1	0.3	0.6	0.2	-0.8
HDL Cholesterol	0.1	0.1	0.3	-0.0	0.5
Schizophrenia (2014)	0.1	0.2	0.3	-0.6	0.3
Smoking Status	0.1	0.1	0.2	-0.5	0.3
Cardiovascular Disease	0.1	0.3	0.4	-0.4	-0.6
Hypothyroidism (self reported)	0.1	0.3	0.6	-0.8	-0.2
Hair Pigment	0.1	1.9	3.9	0.0	2.0
Relative age of first facial hair	0.1	0.3	0.6	0.8	-0.1
Medication: Co-codamol	0.1	0.2	0.2	0.4	0.4
Trunk fat percentage	0.1	0.3	0.6	0.1	0.8
Townsend deprivation index at recruitment	0.1	0.2	0.3	-0.5	0.1
Maternal smoking around birth	0.1	0.1	0.2	-0.1	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.5	-0.2
Taking other prescription medications	0.1	0.2	0.3	0.2	0.5
Sitting height	0.1	0.8	1.6	-0.1	1.3
Trunk fat mass	0.1	0.3	0.6	0.0	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.2	0.3	-0.5
Neuroticism score	0.1	0.3	0.5	-0.7	-0.2
Weight	0.1	0.3	0.4	0.3	0.7
Worrier / anxious feelings	0.1	0.1	0.2	-0.2	-0.5
Pulse rate	0.1	0.2	0.3	-0.4	0.5
Noisy workplace	0.1	0.1	0.1	0.4	-0.1
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	0.5	-0.1
Body fat percentage	0.1	0.5	0.9	0.1	1.0
Arm fat-free mass (right)	0.1	0.3	0.5	-0.1	0.7
Health satisfaction	0.1	0.2	0.3	-0.5	-0.3
Angina (self-reported)	0.1	0.1	0.2	0.3	0.4
Mean time to correctly identify matches	0.1	0.1	0.3	-0.1	0.5
Heart disease (mother)	0.1	0.1	0.2	0.1	0.5
Whole body fat mass	0.1	0.3	0.6	0.1	0.7
Leg fat mass (right)	0.1	0.5	1.0	-0.2	1.0
Pulse rate, automated reading	0.1	0.4	0.4	0.6	0.6
Comparative height size at age 10	0.1	0.3	0.5	0.7	0.4
Chest pain or discomfort	0.1	0.1	0.3	-0.5	-0.1
Leg pain on walking	0.1	0.1	0.2	-0.4	-0.2
Medication: Aspirin	0.1	0.1	0.2	0.1	0.5
Smoking status: Previous	0.1	0.2	0.3	0.2	-0.6
Arm fat percentage (left)	0.1	0.2	0.4	-0.2	0.6
Arm fat mass (left)	0.1	0.2	0.5	0.2	0.7
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.5	-0.1
Alcohol drinker status: Never	0.1	0.2	0.3	0.5	-0.2
Arm fat-free mass (left)	0.1	0.3	0.5	0.1	0.7
Irritability	0.1	0.2	0.4	0.1	-0.7
Age started oral contraceptive pill	0.1	0.2	0.3	-0.3	-0.5
Heart disease (siblings)	0.1	0.1	0.1	0.3	0.1
Impedance of whole body	0.1	0.5	0.7	0.8	0.6
Leg fat mass (left)	0.1	0.3	0.6	-0.2	0.8
Arm predicted mass (left)	0.1	0.3	0.4	0.4	0.6
Bipolar Disorder or Schizophrenia	0.0	0.1	0.2	-0.4	0.1
Neuroticism (Nagel 2018)	0.0	0.0	0.0	-0.0	-0.1
Blood Eosinophil Count	0.0	0.3	0.3	0.6	-0.6
Heel T-Score	0.0	0.3	0.4	-0.6	0.5
BMI	0.0	0.2	0.3	-0.2	0.5
Height	0.0	0.4	0.4	0.6	0.6
Systolic blood pressure, automated reading	0.0	0.0	0.1	-0.1	-0.3
Leg fat-free mass (left)	0.0	0.1	0.1	-0.3	-0.1
Qualifications: CSEs or equivalent	0.0	0.1	0.1	-0.3	-0.2
Diverticular disease/diverticulitis (self-reported)	0.0	0.1	0.1	0.1	-0.3
Medication: Levothyroxine sodium	0.0	0.1	0.1	-0.3	-0.2
Body mass index (BMI)	0.0	0.1	0.2	0.2	0.5
Leg predicted mass (left)	0.0	0.1	0.1	-0.3	-0.1
Waist circumference	0.0	0.0	0.0	0.2	0.0
Past tobacco smoking	0.0	0.1	0.1	0.3	0.3
Ever unenthusiastic/disinterested for a whole week	0.0	0.1	0.1	-0.2	-0.2
Illnesses of siblings	0.0	0.1	0.1	0.2	0.3
Impedance of arm (right)	0.0	0.2	0.3	0.6	0.4
Arm fat percentage (right)	0.0	0.2	0.3	-0.2	0.5
Trunk fat-free mass	0.0	0.1	0.2	0.0	0.4
Father’s age at death	0.0	0.1	0.1	-0.3	-0.2
Impedance of arm (left)	0.0	0.0	0.0	0.1	0.1
Arm fat mass (right)	0.0	0.2	0.3	-0.1	0.5
Trunk predicted mass	0.0	0.1	0.3	0.1	0.5
Standing height	0.0	0.1	0.2	0.4	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.1	0.1	-0.3	0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	-0.2	-0.3
Glaucoma (self-reported)	0.0	0.0	0.0	-0.0	-0.1
Age at first live birth	0.0	0.0	0.1	-0.2	-0.0
Emphysema/chronic bronchitis	0.0	0.0	0.0	0.2	-0.2
Arm predicted mass (right)	0.0	0.1	0.2	0.0	0.4
Had major operations	0.0	0.1	0.1	0.2	-0.2
Age at last live birth	0.0	0.0	0.0	-0.1	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	-0.1	-0.1
Whole body fat-free mass	0.0	0.0	0.0	-0.2	0.2
Leg fat-free mass (right)	0.0	0.2	0.2	-0.3	-0.5
Ever had bowel cancer screening	0.0	0.0	0.1	-0.3	0.0
Qualifications: nursing, teaching	0.0	0.0	0.1	0.2	0.1
Whole body water mass	0.0	0.1	0.1	-0.3	0.2
Leg predicted mass (right)	0.0	0.1	0.2	-0.3	-0.4
Ever smoked	0.0	0.0	0.0	-0.2	0.0
Basal metabolic rate	0.0	0.1	0.1	-0.1	0.3
Diastolic blood pressure, automated reading	0.0	0.0	0.1	-0.1	-0.3

Hub : Genes

PTGER4

Models

Trait associations